Rattus norvegicus

0 known processes

Itch

itchy E3 ubiquitin protein ligase homolog (mouse)

Itch biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.075
oxoacid metabolic processGO:00434362900.065
cellular amino acid metabolic processGO:00065201070.056
carboxylic acid metabolic processGO:00197522890.056
carbohydrate derivative metabolic processGO:19011353460.051
organophosphate metabolic processGO:00196373700.043
nucleobase containing small molecule metabolic processGO:00550863160.041
glycosyl compound metabolic processGO:19016571820.040
cellular component assemblyGO:00226073600.040
organic substance catabolic processGO:19015753160.038
Rat
lipid metabolic processGO:00066292830.038
ribonucleoside metabolic processGO:00091191740.038
catabolic processGO:00090563510.038
Rat
purine nucleoside metabolic processGO:00422781690.038
purine containing compound metabolic processGO:00725212530.037
regulation of rna biosynthetic processGO:20011413810.034
intracellular signal transductionGO:00355563140.033
nucleoside metabolic processGO:00091161790.033
nucleic acid templated transcriptionGO:00976593790.032
rna metabolic processGO:00160704060.032
rna biosynthetic processGO:00327743800.032
cellular ketone metabolic processGO:0042180510.031
regulation of cellular amino acid metabolic processGO:000652120.031
regulation of phosphate metabolic processGO:00192203490.031
secretionGO:00469033070.031
central nervous system developmentGO:00074173110.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
nucleotide metabolic processGO:00091172790.030
regulation of nervous system developmentGO:00519602640.030
Rat
regulation of multicellular organismal developmentGO:20000263760.030
Rat
regulation of cellular ketone metabolic processGO:0010565270.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
amine metabolic processGO:0009308380.030
neuron developmentGO:00486662860.029
Rat
ribonucleotide metabolic processGO:00092592310.029
cellular catabolic processGO:00442482950.029
regulation of rna metabolic processGO:00512523910.029
vesicle mediated transportGO:00161921810.029
Rat Fly
regulation of phosphorus metabolic processGO:00511743490.028
regulation of transcription dna templatedGO:00063553740.028
regulation of cellular amine metabolic processGO:003323880.028
regulation of molecular functionGO:00650093980.027
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.027
cellular amine metabolic processGO:0044106380.027
reproductive processGO:00224143720.027
nucleoside phosphate metabolic processGO:00067532830.027
coenzyme metabolic processGO:0006732860.026
purine nucleotide metabolic processGO:00061632290.026
cellular lipid metabolic processGO:00442552080.026
protein phosphorylationGO:00064683450.025
cellular component biogenesisGO:00440853680.025
regulation of neuron projection developmentGO:00109751610.025
Rat
regulation of catalytic activityGO:00507903040.025
ribose phosphate metabolic processGO:00196932350.025
single organism catabolic processGO:00447122830.025
positive regulation of biosynthetic processGO:00098913190.024
purine ribonucleotide metabolic processGO:00091502270.024
regulation of phosphorylationGO:00423252480.024
transcription dna templatedGO:00063513770.024
response to inorganic substanceGO:00100353770.024
regulation of cell projection organizationGO:00313441750.024
Rat
multicellular organism reproductionGO:00325042330.024
neuron differentiationGO:00301823680.023
Rat
cell projection organizationGO:00300303020.023
Rat
regulation of cellular component organizationGO:00511283680.023
Rat
positive regulation of phosphorus metabolic processGO:00105622620.023
macromolecular complex subunit organizationGO:00439333390.023
regulation of apoptotic processGO:00429813350.023
cation transportGO:00068123820.022
Rat
negative regulation of metabolic processGO:00098923310.022
regulation of cell differentiationGO:00455953200.022
Rat
sulfur compound metabolic processGO:0006790700.021
homeostatic processGO:00425923310.021
regulation of signal transductionGO:00099663180.021
Fly
single organism biosynthetic processGO:00447113420.021
apoptotic processGO:00069153810.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
reproductionGO:00000032450.021
regulation of protein metabolic processGO:00512462890.021
Rat
multi organism reproductive processGO:00447032620.021
organic cyclic compound catabolic processGO:19013611750.020
cellular response to endogenous stimulusGO:00714953770.020
positive regulation of cellular biosynthetic processGO:00313282950.020
single organism reproductive processGO:00447022970.020
brain developmentGO:00074202470.020
regulation of neurogenesisGO:00507672470.020
Rat
multicellular organismal reproductive processGO:00486092330.020
positive regulation of cellular amine metabolic processGO:003324030.020
response to nutrient levelsGO:00316673700.020
purine ribonucleoside metabolic processGO:00461281680.020
response to extracellular stimulusGO:00099913800.019
regulation of programmed cell deathGO:00430673410.019
positive regulation of multicellular organismal processGO:00512403870.019
regulation of protein modification processGO:00313991940.019
positive regulation of gene expressionGO:00106282440.019
regulation of cell developmentGO:00602842630.019
Rat
response to growth factorGO:00708481890.019
heterocycle catabolic processGO:00467001670.019
cellular response to oxygen containing compoundGO:19017013860.019
regulation of system processGO:00440572080.019
Rat
positive regulation of phosphate metabolic processGO:00459372620.019
cofactor metabolic processGO:0051186950.019
nucleobase containing compound catabolic processGO:00346551520.019
programmed cell deathGO:00125013920.019
protein complex assemblyGO:00064612630.018
regulation of catabolic processGO:00098941130.018
Rat
organophosphate catabolic processGO:00464341480.018
positive regulation of molecular functionGO:00440932300.018
positive regulation of protein phosphorylationGO:00019341350.018
positive regulation of developmental processGO:00510942830.018
locomotionGO:00400112370.018
neuron projection developmentGO:00311752730.018
Rat
head developmentGO:00603222470.018
regulation of neuron differentiationGO:00456642080.018
Rat
response to nutrientGO:00075842480.018
ras protein signal transductionGO:0007265290.018
positive regulation of neurogenesisGO:00507691650.018
chemical homeostasisGO:00488782920.018
cellular homeostasisGO:00197252520.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
positive regulation of cell differentiationGO:00455972170.018
response to peptide hormoneGO:00434342780.018
positive regulation of cell developmentGO:00107201760.018
cellular response to organic cyclic compoundGO:00714072020.018
nucleotide catabolic processGO:00091661390.018
organelle organizationGO:00069962660.018
cellular response to hormone stimulusGO:00328702470.018
secretion by cellGO:00329402480.018
cellular nitrogen compound catabolic processGO:00442701630.017
ion transmembrane transportGO:00342203650.017
Rat
response to peptideGO:19016522920.017
transcription from rna polymerase ii promoterGO:00063662520.017
negative regulation of cellular metabolic processGO:00313242810.017
positive regulation of nervous system developmentGO:00519621780.017
response to acid chemicalGO:00011012220.017
small gtpase mediated signal transductionGO:0007264360.017
positive regulation of phosphorylationGO:00423271770.017
oxidation reduction processGO:00551143040.017
negative regulation of macromolecule metabolic processGO:00106052600.017
response to metal ionGO:00100382530.017
purine containing compound catabolic processGO:00725231380.017
macromolecular complex assemblyGO:00650032730.017
metal ion transportGO:00300012890.017
Rat
regulation of intracellular signal transductionGO:19025312180.017
positive regulation of signal transductionGO:00099671750.017
immune system processGO:00023762040.017
Rat
aromatic compound catabolic processGO:00194391680.017
cellular chemical homeostasisGO:00550822470.017
single organism intracellular transportGO:19025821660.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
anterior posterior pattern specificationGO:000995210.017
anatomical structure morphogenesisGO:00096532980.017
Rat Fly
purine ribonucleotide catabolic processGO:00091541360.017
carbohydrate derivative catabolic processGO:19011361470.017
neurological system processGO:00508772190.017
purine ribonucleoside catabolic processGO:00461301240.017
alpha amino acid metabolic processGO:1901605710.017
synaptic transmissionGO:00072682350.016
response to corticosteroidGO:00319602350.016
ribonucleotide catabolic processGO:00092611360.016
single organism organelle organizationGO:19025891800.016
response to woundingGO:00096112540.016
nucleoside phosphate catabolic processGO:19012921400.016
cellular response to stressGO:00335542690.016
positive regulation of rna metabolic processGO:00512542030.016
positive regulation of cellular component organizationGO:00511302000.016
Rat
chromosome segregationGO:000705920.016
response to oxidative stressGO:00069791860.016
ribonucleoside catabolic processGO:00424541260.016
cell migrationGO:00164771970.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
regulation of cell proliferationGO:00421273590.016
positive regulation of response to stimulusGO:00485842850.016
protein complex subunit organizationGO:00718223020.016
positive regulation of transcription dna templatedGO:00458931970.016
positive regulation of protein metabolic processGO:00512471780.016
Rat
regulation of protein phosphorylationGO:00019321830.015
regulation of cellular protein metabolic processGO:00322682670.015
negative regulation of transportGO:00510511360.015
Rat
nucleoside triphosphate metabolic processGO:00091411440.015
cellular component movementGO:00069282480.015
regulation of membrane potentialGO:00423911100.015
Rat
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
protein complex biogenesisGO:00702712630.015
negative regulation of cellular biosynthetic processGO:00313271610.015
organonitrogen compound catabolic processGO:19015651790.015
positive regulation of cellular protein metabolic processGO:00322701670.015
heart morphogenesisGO:000300730.015
positive regulation of cell proliferationGO:00082842490.015
transmembrane transportGO:00550854120.015
Rat
cellular response to growth factor stimulusGO:00713631620.015
cellular response to lipidGO:00713962010.015
negative regulation of cell deathGO:00605482290.015
cell morphogenesisGO:00009021420.015
Rat
regulation of neuron apoptotic processGO:0043523830.014
positive regulation of neuron projection developmentGO:0010976990.014
negative regulation of gene expressionGO:00106291990.014
response to hypoxiaGO:00016662310.014
growthGO:00400071650.014
protein oligomerizationGO:00512591910.014
muscle system processGO:00030121150.014
tissue developmentGO:00098882520.014
response to carbohydrateGO:00097431830.014
positive regulation of cell projection organizationGO:00313461110.014
positive regulation of rna biosynthetic processGO:19026801970.014
negative regulation of apoptotic processGO:00430661810.014
cell cell signalingGO:00072673350.014
regulation of kinase activityGO:00435491170.014
positive regulation of cell communicationGO:00106472710.014
cellular cation homeostasisGO:00300031800.014
negative regulation of programmed cell deathGO:00430691830.014
purine nucleoside catabolic processGO:00061521240.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
regulation of cellular catabolic processGO:00313291010.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
metal ion homeostasisGO:00550651860.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
response to bacteriumGO:00096172000.014
axis specificationGO:000979840.014
embryonic pattern specificationGO:000988010.014
response to hexoseGO:00097461440.014
regulation of transferase activityGO:00513381230.014
purine nucleotide catabolic processGO:00061951360.014
regulation of purine nucleotide metabolic processGO:19005421150.014
response to external biotic stimulusGO:00432072210.014
cellular response to external stimulusGO:00714961180.013
nucleoside triphosphate catabolic processGO:00091431230.013
leukocyte activationGO:0045321760.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
ion homeostasisGO:00508012120.013
glycosyl compound catabolic processGO:19016581260.013
negative regulation of response to stimulusGO:00485851550.013
Fly
positive regulation of neuron differentiationGO:00456661260.013
positive regulation of signalingGO:00230562700.013
organophosphate biosynthetic processGO:00904071430.013
mapk cascadeGO:00001651400.013
protein localizationGO:00081041910.013
Fly
defense responseGO:00069521940.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
carbohydrate derivative biosynthetic processGO:19011371240.013
organonitrogen compound biosynthetic processGO:19015661670.013
response to glucocorticoidGO:00513842230.013
macromolecule localizationGO:00330362520.013
Fly
cellular response to nitrogen compoundGO:19016992100.013
maintenance of locationGO:0051235170.013
Fly
regulation of hormone levelsGO:00108171870.013
lipid storageGO:001991510.013
Fly
regulation of cellular localizationGO:00603412630.013
g protein coupled receptor signaling pathwayGO:00071862420.013
nucleoside catabolic processGO:00091641260.013
response to biotic stimulusGO:00096072260.013
intracellular transportGO:00469071850.013
spindle organizationGO:000705120.012
regulation of secretion by cellGO:19035302080.012
reactive nitrogen species metabolic processGO:200105710.012
sex differentiationGO:00075481130.012
response to ketoneGO:19016541820.012
localization of cellGO:00516742020.012
negative regulation of cell communicationGO:00106481580.012
Fly
regulation of nucleotide metabolic processGO:00061401170.012
carbohydrate metabolic processGO:00059751300.012
anion transportGO:00068201780.012
response to cytokineGO:00340972150.012
circulatory system processGO:00030131830.012
negative regulation of biosynthetic processGO:00098901680.012
sexual reproductionGO:00199531480.012
response to decreased oxygen levelsGO:00362932370.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cytoplasmic transportGO:00164821150.012
negative regulation of cellular protein metabolic processGO:00322691060.012
regulation of neuron deathGO:19012141150.012
cellular response to organonitrogen compoundGO:00714171970.012
response to monosaccharideGO:00342841590.012
positive regulation of transportGO:00510502450.012
Rat
single organism carbohydrate metabolic processGO:00447231180.012
proteolysisGO:00065081750.012
gtp metabolic processGO:0046039720.012
signal transduction by phosphorylationGO:00230141440.012
male gamete generationGO:0048232990.012
inorganic ion transmembrane transportGO:00986602290.012
Rat
cellular ion homeostasisGO:00068731840.012
peptidyl amino acid modificationGO:00181931260.012
positive regulation of protein modification processGO:00314011420.012
response to vitaminGO:00332731310.011
negative regulation of innate immune responseGO:004582440.011
response to glucoseGO:00097491360.011
agingGO:00075682410.011
cellular calcium ion homeostasisGO:00068741600.011
guanosine containing compound metabolic processGO:1901068740.011
phospholipid metabolic processGO:0006644610.011
response to lipopolysaccharideGO:00324961910.011
response to oxygen levelsGO:00704822650.011
protein autophosphorylationGO:0046777660.011
cardiovascular system developmentGO:00723581340.011
rhythmic processGO:00485111560.011
salivary gland developmentGO:000743130.011
response to molecule of bacterial originGO:00022371940.011
cell morphogenesis involved in differentiationGO:00009041190.011
Rat
cell motilityGO:00488702020.011
circulatory system developmentGO:00723591340.011
negative regulation of molecular functionGO:00440921330.011
Rat
gtp catabolic processGO:0006184710.011
glycerolipid metabolic processGO:0046486670.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
reproductive system developmentGO:00614581280.011
gamete generationGO:00072761240.011
response to radiationGO:00093141370.011
cell growthGO:00160491040.011
forebrain developmentGO:0030900980.011
organic hydroxy compound metabolic processGO:19016151150.011
eye morphogenesisGO:004859240.011
nucleotide biosynthetic processGO:0009165980.011
regenerationGO:00310991630.011
positive regulation of intracellular signal transductionGO:19025331380.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
divalent metal ion transportGO:00708381320.011
salivary gland morphogenesisGO:000743510.011
gliogenesisGO:0042063930.011
negative regulation of cell cycle phase transitionGO:190198840.011
hormone secretionGO:00468791150.010
dephosphorylationGO:0016311980.010
sequestering of calcium ionGO:005120880.010
gonad developmentGO:00084061040.010
developmental growthGO:00485891000.010
regulation of hydrolase activityGO:00513361430.010
regulation of mapk cascadeGO:00434081160.010
reproductive structure developmentGO:00486081280.010
regulation of cell migrationGO:00303341280.010
chemosensory behaviorGO:000763520.010
defense response to gram negative bacteriumGO:005082930.010
cell cycle checkpointGO:000007520.010
spermatogenesisGO:0007283990.010
negative regulation of signalingGO:00230571570.010
Fly
regulation of anatomical structure sizeGO:00900661350.010
female pregnancyGO:00075651220.010
positive regulation of transferase activityGO:0051347810.010
positive regulation of catalytic activityGO:00430851840.010
multicellular organism growthGO:003526410.010
cellular macromolecule localizationGO:00707271220.010
calcium ion homeostasisGO:00550741620.010
monocarboxylic acid metabolic processGO:00327871520.010
dna metabolic processGO:0006259960.010

Itch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.026
disease of anatomical entityDOID:700.026
central nervous system diseaseDOID:33100.016
musculoskeletal system diseaseDOID:1700.016
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.012
sensory system diseaseDOID:005015500.011
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010
cancerDOID:16200.010