IMP: Integrative Multi-species Prediction

Rattus norvegicus

13 known processes

Uso1

USO1 homolog, vesicle docking protein (yeast)

(Aliases: Vdp,TAP)

RGD: 621604
Entrez: 56042
Ensembl: ENSRNOG00000002301
UniProtKB: P41542

Process Predictions
Disease Predictions

Uso1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
intra golgi vesicle mediated transport	GO:0006891	3	0.382
golgi vesicle transport	GO:0048193	22	0.271
intracellular transport	GO:0046907	185	0.183
purine containing compound catabolic process	GO:0072523	138	0.143
regulation of ion transport	GO:0043269	245	0.140
vesicle mediated transport	GO:0016192	181	0.131
single organism intracellular transport	GO:1902582	166	0.129
cellular response to stress	GO:0033554	269	0.113
organelle organization	GO:0006996	266	0.109
cell migration	GO:0016477	197	0.096
response to biotic stimulus	GO:0009607	226	0.092
response to other organism	GO:0051707	220	0.084
cell motility	GO:0048870	202	0.084
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.083
secretion by cell	GO:0032940	248	0.080
neuron projection development	GO:0031175	273	0.078
response to extracellular stimulus	GO:0009991	380	0.076
regulation of hydrolase activity	GO:0051336	143	0.076
response to external biotic stimulus	GO:0043207	221	0.075
macromolecule localization	GO:0033036	252	0.070
response to toxic substance	GO:0009636	133	0.067
central nervous system development	GO:0007417	311	0.066
regulation of multicellular organismal development	GO:2000026	376	0.066
regulation of protein modification process	GO:0031399	194	0.066
positive regulation of catalytic activity	GO:0043085	184	0.064
single organism catabolic process	GO:0044712	283	0.064
organelle inheritance	GO:0048308	2	0.064
response to cytokine	GO:0034097	215	0.062
regulation of anatomical structure morphogenesis	GO:0022603	141	0.061
golgi organization	GO:0007030	17	0.060
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.059
response to nutrient levels	GO:0031667	370	0.058
positive regulation of phosphorus metabolic process	GO:0010562	262	0.058
metal ion transport	GO:0030001	289	0.057
anatomical structure morphogenesis	GO:0009653	298	0.057
cation transport	GO:0006812	382	0.054
single organism organelle organization	GO:1902589	180	0.052
divalent metal ion transport	GO:0070838	132	0.051
homeostatic process	GO:0042592	331	0.051
intracellular signal transduction	GO:0035556	314	0.050
cell morphogenesis	GO:0000902	142	0.050
regulation of phosphorus metabolic process	GO:0051174	349	0.050
positive regulation of cellular component organization	GO:0051130	200	0.048
endocytosis	GO:0006897	84	0.047
nucleotide metabolic process	GO:0009117	279	0.046
organophosphate metabolic process	GO:0019637	370	0.046
negative regulation of metabolic process	GO:0009892	331	0.046
positive regulation of phosphate metabolic process	GO:0045937	262	0.045
regulation of protein transport	GO:0051223	68	0.045
cellular response to endogenous stimulus	GO:0071495	377	0.044
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.043
protein phosphorylation	GO:0006468	345	0.043
regulation of catalytic activity	GO:0050790	304	0.043
microtubule based process	GO:0007017	36	0.042
cellular catabolic process	GO:0044248	295	0.040
carbohydrate derivative catabolic process	GO:1901136	147	0.038
negative regulation of multicellular organismal process	GO:0051241	203	0.038
purine ribonucleotide metabolic process	GO:0009150	227	0.038
neuron projection morphogenesis	GO:0048812	122	0.037
ribonucleotide catabolic process	GO:0009261	136	0.037
synaptic transmission	GO:0007268	235	0.037
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.036
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.036
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.036
positive regulation of biosynthetic process	GO:0009891	319	0.036
neuron development	GO:0048666	286	0.035
head development	GO:0060322	247	0.035
ras protein signal transduction	GO:0007265	29	0.035
regulation of cellular component organization	GO:0051128	368	0.034
cellular response to cytokine stimulus	GO:0071345	127	0.034
retrograde vesicle mediated transport golgi to er	GO:0006890	1	0.033
nucleoside phosphate catabolic process	GO:1901292	140	0.033
regulation of cell differentiation	GO:0045595	320	0.033
negative regulation of cell development	GO:0010721	82	0.033
secretion	GO:0046903	307	0.033
regulation of catabolic process	GO:0009894	113	0.033
response to hypoxia	GO:0001666	231	0.033
cellular component movement	GO:0006928	248	0.032
gtp metabolic process	GO:0046039	72	0.032
positive regulation of hydrolase activity	GO:0051345	86	0.032
regulation of cell morphogenesis	GO:0022604	77	0.032
toxin metabolic process	GO:0009404	9	0.031
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.031
cytoplasmic transport	GO:0016482	115	0.031
pigment biosynthetic process	GO:0046148	4	0.031
positive regulation of protein modification process	GO:0031401	142	0.030
protein transport	GO:0015031	132	0.030
cellular response to unfolded protein	GO:0034620	2	0.030
regulation of neuron differentiation	GO:0045664	208	0.030
regulation of neuron projection development	GO:0010975	161	0.030
regulation of phosphate metabolic process	GO:0019220	349	0.029
cellular amine metabolic process	GO:0044106	38	0.029
catabolic process	GO:0009056	351	0.029
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029
regulation of protein metabolic process	GO:0051246	289	0.028
cellular response to topologically incorrect protein	GO:0035967	3	0.028
muscle contraction	GO:0006936	88	0.028
cellular homeostasis	GO:0019725	252	0.028
regulation of purine nucleotide metabolic process	GO:1900542	115	0.028
chemical homeostasis	GO:0048878	292	0.028
regulation of neurogenesis	GO:0050767	247	0.028
cell projection organization	GO:0030030	302	0.028
regulation of cell motility	GO:2000145	131	0.028
locomotion	GO:0040011	237	0.028
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.027
localization of cell	GO:0051674	202	0.027
negative regulation of cell communication	GO:0010648	158	0.027
cell morphogenesis involved in differentiation	GO:0000904	119	0.027
organelle localization	GO:0051640	55	0.027
aging	GO:0007568	241	0.027
cytoskeleton organization	GO:0007010	111	0.027
synaptic vesicle transport	GO:0048489	23	0.027
negative regulation of signaling	GO:0023057	157	0.027
establishment of protein localization to organelle	GO:0072594	44	0.026
regulation of signal transduction	GO:0009966	318	0.026
maintenance of location	GO:0051235	17	0.026
establishment of protein localization	GO:0045184	141	0.026
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	3	0.026
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.026
cell cell signaling	GO:0007267	335	0.026
regulation of cellular localization	GO:0060341	263	0.026
regulation of cell projection organization	GO:0031344	175	0.025
negative regulation of signal transduction	GO:0009968	83	0.025
regulation of cellular protein metabolic process	GO:0032268	267	0.025
purine ribonucleoside catabolic process	GO:0046130	124	0.025
positive regulation of cell migration	GO:0030335	96	0.025
transmembrane transport	GO:0055085	412	0.025
cellular component morphogenesis	GO:0032989	155	0.025
reproductive process	GO:0022414	372	0.025
organophosphate catabolic process	GO:0046434	148	0.025
positive regulation of cell differentiation	GO:0045597	217	0.025
regulation of nervous system development	GO:0051960	264	0.025
synaptic vesicle endocytosis	GO:0048488	4	0.024
neuron differentiation	GO:0030182	368	0.024
axon cargo transport	GO:0008088	1	0.024
small gtpase mediated signal transduction	GO:0007264	36	0.024
cellular biogenic amine biosynthetic process	GO:0042401	4	0.024
purine containing compound metabolic process	GO:0072521	253	0.024
macroautophagy	GO:0016236	4	0.024
protein secretion	GO:0009306	34	0.023
anterograde axon cargo transport	GO:0008089	1	0.023
regulation of molecular function	GO:0065009	398	0.023
purine ribonucleotide catabolic process	GO:0009154	136	0.023
reproduction	GO:0000003	245	0.023
response to peptide	GO:1901652	292	0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.023
negative regulation of neurogenesis	GO:0050768	78	0.022
nucleoside phosphate metabolic process	GO:0006753	283	0.022
regulation of cell migration	GO:0030334	128	0.022
protein targeting	GO:0006605	61	0.022
cellular chemical homeostasis	GO:0055082	247	0.022
ribonucleotide metabolic process	GO:0009259	231	0.022
negative regulation of developmental process	GO:0051093	125	0.022
brain development	GO:0007420	247	0.022
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.021
multicellular organismal reproductive process	GO:0048609	233	0.021
purine nucleotide metabolic process	GO:0006163	229	0.021
regulation of kinase activity	GO:0043549	117	0.021
atp catabolic process	GO:0006200	54	0.021
regulation of transcription dna templated	GO:0006355	374	0.021
positive regulation of protein kinase activity	GO:0045860	73	0.020
ribose phosphate metabolic process	GO:0019693	235	0.020
regulation of membrane potential	GO:0042391	110	0.020
protein complex assembly	GO:0006461	263	0.020
cellular response to external stimulus	GO:0071496	118	0.020
cellular ion homeostasis	GO:0006873	184	0.020
positive regulation of protein phosphorylation	GO:0001934	135	0.020
nucleobase containing compound catabolic process	GO:0034655	152	0.020
neurological system process	GO:0050877	219	0.020
protein localization	GO:0008104	191	0.019
single organism membrane organization	GO:0044802	74	0.019
centrosome organization	GO:0051297	1	0.019
eye morphogenesis	GO:0048592	4	0.019
amine metabolic process	GO:0009308	38	0.019
nitrogen compound transport	GO:0071705	229	0.019
lipid storage	GO:0019915	1	0.018
multicellular organismal signaling	GO:0035637	44	0.018
cerebellar purkinje cell layer development	GO:0021680	2	0.018
cellular protein localization	GO:0034613	122	0.018
regulation of protein phosphorylation	GO:0001932	183	0.018
immune system process	GO:0002376	204	0.018
cell part morphogenesis	GO:0032990	123	0.018
negative regulation of cell death	GO:0060548	229	0.018
hindbrain morphogenesis	GO:0021575	2	0.018
organic substance catabolic process	GO:1901575	316	0.017
positive regulation of rna metabolic process	GO:0051254	203	0.017
proteolysis	GO:0006508	175	0.017
cellular nitrogen compound catabolic process	GO:0044270	163	0.017
cation homeostasis	GO:0055080	195	0.017
regulation of metal ion transport	GO:0010959	118	0.017
single organism cellular localization	GO:1902580	102	0.017
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.017
regulation of arp2 3 complex mediated actin nucleation	GO:0034315	2	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.017
anterior posterior pattern specification	GO:0009952	1	0.016
ribonucleoside catabolic process	GO:0042454	126	0.016
apoptotic process	GO:0006915	381	0.016
cellular response to starvation	GO:0009267	27	0.016
negative regulation of macromolecule metabolic process	GO:0010605	260	0.016
protein localization to organelle	GO:0033365	57	0.016
positive regulation of cellular biosynthetic process	GO:0031328	295	0.016
regulation of cell development	GO:0060284	263	0.016
negative regulation of neuron projection development	GO:0010977	46	0.016
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	5	0.016
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.016
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.016
multicellular organism reproduction	GO:0032504	233	0.016
positive regulation of gene expression	GO:0010628	244	0.016
arp2 3 complex mediated actin nucleation	GO:0034314	2	0.015
cell projection morphogenesis	GO:0048858	123	0.015
reproductive system development	GO:0061458	128	0.015
regulation of cellular catabolic process	GO:0031329	101	0.015
glycosyl compound catabolic process	GO:1901658	126	0.015
organonitrogen compound catabolic process	GO:1901565	179	0.015
organic acid metabolic process	GO:0006082	292	0.015
response to monosaccharide	GO:0034284	159	0.015
neuromuscular synaptic transmission	GO:0007274	2	0.015
carboxylic acid metabolic process	GO:0019752	289	0.015
organic cyclic compound catabolic process	GO:1901361	175	0.015
ribonucleoside metabolic process	GO:0009119	174	0.015
positive regulation of cellular protein metabolic process	GO:0032270	167	0.015
regulation of phosphorylation	GO:0042325	248	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.015
macromolecular complex subunit organization	GO:0043933	339	0.015
er associated ubiquitin dependent protein catabolic process	GO:0030433	1	0.015
regulation of locomotion	GO:0040012	148	0.015
purine nucleotide catabolic process	GO:0006195	136	0.015
muscle system process	GO:0003012	115	0.015
cellular metal ion homeostasis	GO:0006875	172	0.014
cellular response to biotic stimulus	GO:0071216	59	0.014
negative regulation of neuron differentiation	GO:0045665	62	0.014
transmission of nerve impulse	GO:0019226	42	0.014
positive regulation of transport	GO:0051050	245	0.014
negative regulation of gene expression	GO:0010629	199	0.014
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
cellular response to oxygen containing compound	GO:1901701	386	0.014
positive regulation of nucleoside metabolic process	GO:0045979	55	0.014
response to oxygen levels	GO:0070482	265	0.014
calcium ion transport	GO:0006816	131	0.014
positive regulation of phosphorylation	GO:0042327	177	0.014
regulation of dendrite development	GO:0050773	59	0.014
heterocycle catabolic process	GO:0046700	167	0.014
protein complex biogenesis	GO:0070271	263	0.014
regulation of gtpase activity	GO:0043087	57	0.014
positive regulation of protein metabolic process	GO:0051247	178	0.014
response to carbohydrate	GO:0009743	183	0.014
negative regulation of cell projection organization	GO:0031345	50	0.014
endomembrane system organization	GO:0010256	48	0.014
nucleic acid templated transcription	GO:0097659	379	0.014
nucleoside triphosphate catabolic process	GO:0009143	123	0.013
cellular response to extracellular stimulus	GO:0031668	73	0.013
amide transport	GO:0042886	105	0.013
establishment of vesicle localization	GO:0051650	31	0.013
cellular response to growth factor stimulus	GO:0071363	162	0.013
rna biosynthetic process	GO:0032774	380	0.013
nucleoside triphosphate metabolic process	GO:0009141	144	0.013
cellular component assembly	GO:0022607	360	0.013
purine nucleoside metabolic process	GO:0042278	169	0.013
regulation of intracellular signal transduction	GO:1902531	218	0.013
negative regulation of apoptotic process	GO:0043066	181	0.013
nucleotide catabolic process	GO:0009166	139	0.013
defense response	GO:0006952	194	0.013
positive regulation of multicellular organismal process	GO:0051240	387	0.013
positive regulation of neuron differentiation	GO:0045666	126	0.013
nucleoside catabolic process	GO:0009164	126	0.013
positive regulation of transcription dna templated	GO:0045893	197	0.013
divalent inorganic cation transport	GO:0072511	134	0.013
protein complex subunit organization	GO:0071822	302	0.013
cellular response to nutrient levels	GO:0031669	60	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
negative regulation of molecular function	GO:0044092	133	0.012
peptidyl amino acid modification	GO:0018193	126	0.012
negative regulation of cellular metabolic process	GO:0031324	281	0.012
regulation of postsynaptic membrane potential	GO:0060078	25	0.012
positive regulation of nucleotide metabolic process	GO:0045981	91	0.012
positive regulation of transferase activity	GO:0051347	81	0.012
endoplasmic reticulum membrane organization	GO:0090158	1	0.012
regulation of rna biosynthetic process	GO:2001141	381	0.012
negative regulation of nervous system development	GO:0051961	79	0.012
cellular calcium ion homeostasis	GO:0006874	160	0.012
centrosome cycle	GO:0007098	1	0.012
mesoderm development	GO:0007498	2	0.012
positive regulation of neuron projection development	GO:0010976	99	0.012
bmp signaling pathway	GO:0030509	4	0.012
carbohydrate derivative metabolic process	GO:1901135	346	0.012
carbohydrate homeostasis	GO:0033500	75	0.012
regulation of dendrite morphogenesis	GO:0048814	33	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012
metal ion homeostasis	GO:0055065	186	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.012
purine ribonucleoside metabolic process	GO:0046128	168	0.012
positive regulation of secretion	GO:0051047	140	0.012
negative regulation of phosphorylation	GO:0042326	57	0.011
extracellular matrix constituent secretion	GO:0070278	4	0.011
response to growth factor	GO:0070848	189	0.011
aromatic compound catabolic process	GO:0019439	168	0.011
polyamine biosynthetic process	GO:0006596	4	0.011
regulation of secretion by cell	GO:1903530	208	0.011
regulation of vesicle mediated transport	GO:0060627	81	0.011
axis specification	GO:0009798	4	0.011
response to corticosteroid	GO:0031960	235	0.011
lipid localization	GO:0010876	62	0.011
single organism carbohydrate metabolic process	GO:0044723	118	0.011
cellular macromolecular complex assembly	GO:0034622	58	0.011
response to hexose	GO:0009746	144	0.011
intracellular protein transport	GO:0006886	79	0.011
cellular component biogenesis	GO:0044085	368	0.011
protein geranylgeranylation	GO:0018344	4	0.011
response to glucose	GO:0009749	136	0.011
activation of phospholipase d activity	GO:0031584	2	0.011
positive regulation of dendrite development	GO:1900006	35	0.011
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	4	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
response to acid chemical	GO:0001101	222	0.011
vesicle organization	GO:0016050	29	0.011
rna localization	GO:0006403	4	0.011
regulation of protein kinase activity	GO:0045859	105	0.011
taxis	GO:0042330	67	0.010
oxoacid metabolic process	GO:0043436	290	0.010
negative regulation of protein metabolic process	GO:0051248	114	0.010
response to inorganic substance	GO:0010035	377	0.010
regulation of anatomical structure size	GO:0090066	135	0.010
single organism biosynthetic process	GO:0044711	342	0.010
glycerolipid metabolic process	GO:0046486	67	0.010
regulation of system process	GO:0044057	208	0.010
gonad development	GO:0008406	104	0.010
sex differentiation	GO:0007548	113	0.010
reproductive structure development	GO:0048608	128	0.010
transcription dna templated	GO:0006351	377	0.010
negative regulation of jnk cascade	GO:0046329	4	0.010
glycosyl compound metabolic process	GO:1901657	182	0.010
regulation of bmp signaling pathway	GO:0030510	2	0.010
positive regulation of molecular function	GO:0044093	230	0.010
positive regulation of neurogenesis	GO:0050769	165	0.010

Uso1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.021
	disease of anatomical entity	DOID:7	0	0.021

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