Rattus norvegicus

0 known processes

C4b

complement component 4B (Chido blood group)

(Aliases: C4-1,C4a,C4)

C4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
complement activationGO:0006956110.937
Mouse
immune responseGO:00069551040.244
Mouse
activation of immune responseGO:0002253260.193
Mouse
immune effector processGO:0002252530.190
Mouse
positive regulation of response to stimulusGO:00485842850.152
Mouse
positive regulation of immune system processGO:0002684900.120
Mouse
negative regulation of cell deathGO:00605482290.111
neuron deathGO:00709971270.109
macromolecule localizationGO:00330362520.103
humoral immune responseGO:0006959120.098
Mouse
immune system processGO:00023762040.097
Mouse
regulation of immune system processGO:00026821230.095
Mouse
metanephros morphogenesisGO:000333860.095
wound healingGO:00420601220.089
response to extracellular stimulusGO:00099913800.087
Rat
protein activation cascadeGO:0072376120.084
Mouse
regulation of phosphate metabolic processGO:00192203490.079
negative regulation of cellular metabolic processGO:00313242810.078
Rat
multicellular organism reproductionGO:00325042330.078
apoptotic processGO:00069153810.068
multi organism reproductive processGO:00447032620.068
regulation of hydrolase activityGO:00513361430.068
Rat
response to woundingGO:00096112540.067
regulation of protein metabolic processGO:00512462890.067
Rat
response to glucocorticoidGO:00513842230.065
Rat
reproductive processGO:00224143720.063
positive regulation of cell developmentGO:00107201760.062
regulation of immune responseGO:0050776550.062
Mouse
negative regulation of innate immune responseGO:004582440.061
homeostatic processGO:00425923310.060
metanephric glomerulus developmentGO:007222430.054
inflammatory responseGO:00069541500.052
Rat
response to corticosteroidGO:00319602350.051
Rat
intracellular signal transductionGO:00355563140.051
gland developmentGO:00487321550.049
regulation of cellular protein metabolic processGO:00322682670.048
Rat
negative regulation of b cell differentiationGO:004557810.046
single organism behaviorGO:00447081300.045
response to cytokineGO:00340972150.044
platelet derived growth factor receptor alpha signaling pathwayGO:003579010.044
positive regulation of transportGO:00510502450.044
hemostasisGO:0007599260.043
regulation of phosphorus metabolic processGO:00511743490.043
cellular chemical homeostasisGO:00550822470.043
protein maturationGO:0051604680.043
Rat
regulation of molecular functionGO:00650093980.042
Rat
positive regulation of cell projection organizationGO:00313461110.042
regulation of signal transductionGO:00099663180.042
head developmentGO:00603222470.042
calcium ion transportGO:00068161310.041
single organism reproductive processGO:00447022970.041
central nervous system developmentGO:00074173110.040
organonitrogen compound biosynthetic processGO:19015661670.040
b cell mediated immunityGO:001972440.039
Mouse
coagulationGO:0050817280.039
cellular response to lipidGO:00713962010.039
cellular response to cytokine stimulusGO:00713451270.037
myeloid progenitor cell differentiationGO:000231810.036
programmed cell deathGO:00125013920.036
growthGO:00400071650.035
pro t cell differentiationGO:000257210.035
protein localizationGO:00081041910.035
carbohydrate derivative metabolic processGO:19011353460.035
organophosphate metabolic processGO:00196373700.035
response to molecule of bacterial originGO:00022371940.034
cell growthGO:00160491040.034
negative regulation of multicellular organismal processGO:00512412030.034
peptidyl amino acid modificationGO:00181931260.034
response to nutrient levelsGO:00316673700.034
Rat
chemical homeostasisGO:00488782920.034
blood coagulationGO:0007596260.034
agingGO:00075682410.033
negative regulation of macromolecule metabolic processGO:00106052600.033
Rat
protein transportGO:00150311320.032
fibrinolysisGO:004273020.032
positive regulation of myeloid leukocyte differentiationGO:000276370.032
response to glucoseGO:00097491360.032
metanephric nephron morphogenesisGO:007227360.032
establishment of protein localizationGO:00451841410.032
kidney mesenchyme developmentGO:007207420.031
response to monosaccharideGO:00342841590.030
response to lipopolysaccharideGO:00324961910.030
response to peptide hormoneGO:00434342780.030
comma shaped body morphogenesisGO:007204920.029
metanephric mesenchymal cell migrationGO:003578920.028
cell migration involved in metanephros developmentGO:003578820.028
reproductionGO:00000032450.028
positive regulation of blood coagulationGO:003019440.028
glomerulus morphogenesisGO:007210210.028
regulation of protein localizationGO:0032880810.028
cellular response to oxygen containing compoundGO:19017013860.027
response to other organismGO:00517072200.027
regulation of fibrinolysisGO:005191720.027
response to hexoseGO:00097461440.026
regulation of body fluid levelsGO:0050878900.026
positive regulation of erk1 and erk2 cascadeGO:0070374290.026
regulation of apoptotic processGO:00429813350.026
metanephric s shaped body morphogenesisGO:007228420.026
cellular ion homeostasisGO:00068731840.026
positive regulation of neuron projection developmentGO:0010976990.026
cellular cation homeostasisGO:00300031800.026
cellular response to endogenous stimulusGO:00714953770.026
metanephric glomerulus morphogenesisGO:007227510.026
response to hypoxiaGO:00016662310.025
purine containing compound metabolic processGO:00725212530.025
positive regulation of neurogenesisGO:00507691650.025
nucleoside phosphate metabolic processGO:00067532830.025
rhythmic processGO:00485111560.025
regulation of cellular component organizationGO:00511283680.024
cellular amine metabolic processGO:0044106380.024
multi multicellular organism processGO:00447061380.024
retina development in camera type eyeGO:0060041270.024
cellular metal ion homeostasisGO:00068751720.023
positive regulation of immune responseGO:0050778420.023
Mouse
cellular catabolic processGO:00442482950.023
response to acid chemicalGO:00011012220.023
positive regulation of cell differentiationGO:00455972170.023
cellular response to hormone stimulusGO:00328702470.022
innate immune responseGO:0045087350.022
response to bacteriumGO:00096172000.022
response to biotic stimulusGO:00096072260.022
regulation of cell growthGO:0001558850.022
behaviorGO:00076102050.022
response to inorganic substanceGO:00100353770.022
regulation of cell differentiationGO:00455953200.022
regulation of programmed cell deathGO:00430673410.021
cellular homeostasisGO:00197252520.021
protein oligomerizationGO:00512591910.021
amine metabolic processGO:0009308380.021
brain developmentGO:00074202470.020
multicellular organismal reproductive processGO:00486092330.020
cellular amino acid metabolic processGO:00065201070.020
regulation of neuron deathGO:19012141150.020
negative regulation of developmental processGO:00510931250.020
nucleic acid templated transcriptionGO:00976593790.020
regulation of leukocyte differentiationGO:1902105200.019
regulation of protein transportGO:0051223680.019
protein phosphorylationGO:00064683450.019
regulation of protein modification processGO:00313991940.019
positive regulation of cellular component organizationGO:00511302000.019
cellular component assemblyGO:00226073600.019
nephron morphogenesisGO:0072028130.019
response to decreased oxygen levelsGO:00362932370.019
carbohydrate homeostasisGO:0033500750.019
nuclear transportGO:0051169490.019
transcription dna templatedGO:00063513770.019
negative regulation of proteolysisGO:0045861410.019
Rat
positive regulation of gene expressionGO:00106282440.018
nucleobase containing small molecule metabolic processGO:00550863160.018
neuron apoptotic processGO:0051402880.018
negative regulation of cellular protein metabolic processGO:00322691060.018
Rat
negative regulation of apoptotic processGO:00430661810.018
organic acid metabolic processGO:00060822920.018
response to triglycerideGO:003401430.018
kidney vasculature developmentGO:006144060.018
regulation of rna metabolic processGO:00512523910.018
positive regulation of phosphorus metabolic processGO:00105622620.018
response to peptideGO:19016522920.018
positive regulation of cellular protein metabolic processGO:00322701670.018
response to carbohydrateGO:00097431830.018
regulation of establishment of protein localizationGO:0070201690.018
cellular response to corticosteroid stimulusGO:0071384690.017
cell migration involved in kidney developmentGO:003578720.017
positive regulation of signalingGO:00230562700.017
regulation of catalytic activityGO:00507903040.017
Rat
negative regulation of molecular functionGO:00440921330.017
Rat
regulation of cellular amino acid metabolic processGO:000652120.017
positive regulation of nervous system developmentGO:00519621780.017
response to nutrientGO:00075842480.017
Rat
response to growth factorGO:00708481890.017
negative regulation of fibrinolysisGO:005191820.017
positive regulation of multicellular organismal processGO:00512403870.017
positive regulation of hormone secretionGO:0046887650.017
positive regulation of molecular functionGO:00440932300.016
cellular response to hexose stimulusGO:0071331650.016
purine nucleotide metabolic processGO:00061632290.016
cytosolic calcium ion homeostasisGO:00514801400.016
regulation of peptide hormone secretionGO:0090276800.016
positive regulation of intracellular signal transductionGO:19025331380.016
positive regulation of neuron differentiationGO:00456661260.016
glycosyl compound metabolic processGO:19016571820.016
cellular lipid metabolic processGO:00442552080.016
mitotic spindle organizationGO:000705220.016
neurological system processGO:00508772190.016
negative regulation of gene expressionGO:00106291990.016
Rat
maintenance of locationGO:0051235170.015
response to ethanolGO:00454711620.015
regulation of protein maturationGO:1903317500.015
Rat
response to retinoic acidGO:0032526630.015
cognitionGO:0050890920.015
jak stat cascadeGO:0007259260.015
positive regulation of biosynthetic processGO:00098913190.015
regulation of neuron differentiationGO:00456642080.015
sexual reproductionGO:00199531480.015
response to interleukin 1GO:0070555550.015
tissue remodelingGO:0048771400.015
regulation of intracellular signal transductionGO:19025312180.015
cellular nitrogen compound catabolic processGO:00442701630.014
ion homeostasisGO:00508012120.014
protein complex subunit organizationGO:00718223020.014
leukocyte mediated immunityGO:0002443280.014
Mouse
cellular response to platelet derived growth factor stimulusGO:003612070.014
spermatogenesisGO:0007283990.014
divalent metal ion transportGO:00708381320.014
rna metabolic processGO:00160704060.014
neuron differentiationGO:00301823680.014
kidney morphogenesisGO:0060993130.014
cellular response to organic cyclic compoundGO:00714072020.014
positive regulation of developmental processGO:00510942830.014
regulation of rna biosynthetic processGO:20011413810.014
spindle organizationGO:000705120.014
regulation of cellular localizationGO:00603412630.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
glucose homeostasisGO:0042593750.014
urogenital system developmentGO:0001655780.014
regulation of neurogenesisGO:00507672470.014
neuron developmentGO:00486662860.014
calcium ion homeostasisGO:00550741620.014
leukocyte differentiationGO:0002521300.014
response to estradiolGO:00323551640.014
cellular response to nitrogen compoundGO:19016992100.014
regulation of b cell differentiationGO:004557710.013
negative regulation of protein maturationGO:1903318470.013
Rat
carbohydrate derivative biosynthetic processGO:19011371240.013
metanephric mesenchyme developmentGO:007207520.013
nucleotide metabolic processGO:00091172790.013
gamete generationGO:00072761240.013
cytoplasmic transportGO:00164821150.013
tissue developmentGO:00098882520.013
response to ketoneGO:19016541820.013
regulation of neuron projection developmentGO:00109751610.013
metal ion homeostasisGO:00550651860.013
ras protein signal transductionGO:0007265290.013
response to reactive oxygen speciesGO:00003021200.013
female pregnancyGO:00075651220.013
cellular response to acid chemicalGO:0071229750.013
positive regulation of response to woundingGO:1903036340.013
positive regulation of hemostasisGO:190004840.013
lipid localizationGO:0010876620.013
embryonic skeletal system developmentGO:004870630.013
regulation of defense responseGO:0031347680.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
positive regulation of protein phosphorylationGO:00019341350.012
nucleocytoplasmic transportGO:0006913480.012
macromolecular complex assemblyGO:00650032730.012
negative regulation of peptidase activityGO:0010466380.012
Rat
positive regulation of apoptotic processGO:00430651540.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
macromolecular complex subunit organizationGO:00439333390.012
positive regulation of cellular biosynthetic processGO:00313282950.012
regulation of multicellular organismal developmentGO:20000263760.012
kidney developmentGO:0001822670.012
negative regulation of response to stimulusGO:00485851550.012
regulation of growthGO:00400081050.012
positive regulation of protein transportGO:0051222410.012
cellular response to carbohydrate stimulusGO:0071322720.012
positive regulation of immunoglobulin productionGO:000263940.012
regenerationGO:00310991630.012
negative regulation of metabolic processGO:00098923310.012
Rat
immunoglobulin mediated immune responseGO:001606440.012
Mouse
cellular calcium ion homeostasisGO:00068741600.012
oligopeptide transportGO:000685740.012
positive regulation of cellular amine metabolic processGO:003324030.012
negative regulation of neuron deathGO:1901215690.012
negative regulation of humoral immune responseGO:000292140.012
negative regulation of programmed cell deathGO:00430691830.011
oxidation reduction processGO:00551143040.011
organonitrogen compound catabolic processGO:19015651790.011
regulation of ion transportGO:00432692450.011
regulation of transcription dna templatedGO:00063553740.011
secretion by cellGO:00329402480.011
catabolic processGO:00090563510.011
regulation of secretion by cellGO:19035302080.011
artery smooth muscle contractionGO:001482440.011
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011
learning or memoryGO:0007611900.011
positive regulation of cell proliferationGO:00082842490.011
negative regulation of endothelial cell migrationGO:001059630.011
s shaped body morphogenesisGO:007205020.011
cellular response to cobalt ionGO:007127930.011
sequestering of calcium ionGO:005120880.011
cellular response to stressGO:00335542690.011
response to metal ionGO:00100382530.010
cell projection organizationGO:00300303020.010
sequestering of metal ionGO:005123890.010
regulation of cellular amine metabolic processGO:003323880.010
regulation of inflammatory responseGO:0050727480.010
lipid transportGO:0006869610.010
response to phGO:0009268270.010
negative regulation of immune system processGO:0002683390.010
negative regulation of catalytic activityGO:00430861030.010
Rat
multicellular organism growthGO:003526410.010
liver developmentGO:0001889900.010
regulation of endopeptidase activityGO:0052548510.010
Rat
defense response to gram negative bacteriumGO:005082930.010
organic substance catabolic processGO:19015753160.010
cellular response to metal ionGO:0071248550.010
positive regulation of growthGO:0045927550.010
regulation of cellular component movementGO:00512701500.010
regulation of system processGO:00440572080.010
negative regulation of protein processingGO:0010955470.010
Rat
negative regulation of endopeptidase activityGO:0010951360.010
Rat
regulation of cell projection organizationGO:00313441750.010

C4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
skin diseaseDOID:3700.015
integumentary system diseaseDOID:1600.015
disease of metabolismDOID:001466700.015
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010
cancerDOID:16200.010