Rattus norvegicus

42 known processes

Abcb11

ATP-binding cassette, subfamily B (MDR/TAP), member 11

(Aliases: Spgp,Bsep)

Abcb11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
fatty acid metabolic processGO:0006631990.942
organic acid metabolic processGO:00060822920.916
monocarboxylic acid metabolic processGO:00327871520.906
cellular lipid metabolic processGO:00442552080.903
carboxylic acid metabolic processGO:00197522890.815
oxoacid metabolic processGO:00434362900.808
small molecule biosynthetic processGO:00442831240.778
lipid metabolic processGO:00066292830.773
lipid biosynthetic processGO:00086101280.716
single organism biosynthetic processGO:00447113420.640
organic acid biosynthetic processGO:0016053830.618
exogenous drug catabolic processGO:004273810.600
calcitriol biosynthetic process from calciolGO:003637820.558
response to corticosteroidGO:00319602350.550
response to ketoneGO:19016541820.537
response to acid chemicalGO:00011012220.465
vascular process in circulatory systemGO:0003018960.449
carboxylic acid biosynthetic processGO:0046394830.448
organic anion transportGO:00157111320.443
cellular response to xenobiotic stimulusGO:0071466190.427
carboxylic acid transportGO:00469421150.425
response to inorganic substanceGO:00100353770.424
response to peptideGO:19016522920.417
oxidation reduction processGO:00551143040.408
organic acid transportGO:00158491160.378
organic hydroxy compound metabolic processGO:19016151150.366
monocarboxylic acid transportGO:0015718520.360
response to oxidative stressGO:00069791860.342
drug catabolic processGO:004273710.320
insecticide metabolic processGO:001714340.299
drug metabolic processGO:0017144110.281
agingGO:00075682410.280
regulation of tube sizeGO:0035150890.279
response to reactive oxygen speciesGO:00003021200.270
nitrogen compound transportGO:00717052290.268
defense responseGO:00069521940.264
response to xenobiotic stimulusGO:0009410230.259
response to glucocorticoidGO:00513842230.257
regulation of blood pressureGO:0008217830.254
multi multicellular organism processGO:00447061380.250
cellular response to organic cyclic compoundGO:00714072020.246
response to estradiolGO:00323551640.244
drug transmembrane transportGO:0006855130.244
behaviorGO:00076102050.239
rhythmic processGO:00485111560.239
unsaturated fatty acid metabolic processGO:0033559390.239
cellular catabolic processGO:00442482950.235
isoprenoid metabolic processGO:0006720450.229
icosanoid metabolic processGO:0006690380.227
lauric acid metabolic processGO:004825240.227
toxin catabolic processGO:000940710.223
multi organism reproductive processGO:00447032620.222
response to peptide hormoneGO:00434342780.219
steroid metabolic processGO:0008202730.213
single organism behaviorGO:00447081300.211
regulation of blood vessel sizeGO:0050880890.207
female pregnancyGO:00075651220.200
regulation of hormone levelsGO:00108171870.192
catabolic processGO:00090563510.192
response to insecticideGO:0017085210.188
organic substance catabolic processGO:19015753160.183
fatty acid derivative metabolic processGO:1901568380.176
terpenoid metabolic processGO:0006721370.163
response to biotic stimulusGO:00096072260.159
monocarboxylic acid biosynthetic processGO:0072330480.154
response to organophosphorusGO:00466831020.151
lipid transportGO:0006869610.149
halogenated hydrocarbon metabolic processGO:004219740.147
organic hydroxy compound biosynthetic processGO:1901617510.138
g protein coupled receptor signaling pathwayGO:00071862420.136
cellular amino acid metabolic processGO:00065201070.134
steroid biosynthetic processGO:0006694480.128
chemical homeostasisGO:00488782920.126
linoleic acid metabolic processGO:004365140.126
cellular response to corticosteroid stimulusGO:0071384690.124
response to other organismGO:00517072200.122
multicellular organism reproductionGO:00325042330.120
positive regulation of multicellular organismal processGO:00512403870.120
anion transportGO:00068201780.119
toxin metabolic processGO:000940490.116
cellular alcohol biosynthetic processGO:004410820.111
response to cesium ionGO:001016420.111
response to bacteriumGO:00096172000.111
secondary alcohol metabolic processGO:190265220.110
cellular hormone metabolic processGO:0034754490.109
response to nutrientGO:00075842480.109
response to metal ionGO:00100382530.108
amino acid transportGO:0006865700.107
chlorinated hydrocarbon metabolic processGO:004219640.106
liver developmentGO:0001889900.105
fat soluble vitamin biosynthetic processGO:004236220.104
alkaloid metabolic processGO:000982030.103
cellular response to organonitrogen compoundGO:00714171970.103
oxidative demethylationGO:007098920.102
secretionGO:00469033070.101
multicellular organismal reproductive processGO:00486092330.101
negative regulation of cellular metabolic processGO:00313242810.100
response to purine containing compoundGO:00140741260.098
reproductionGO:00000032450.097
epoxygenase p450 pathwayGO:001937310.097
hormone transportGO:00099141210.097
response to molecule of bacterial originGO:00022371940.094
single organism reproductive processGO:00447022970.094
alcohol metabolic processGO:0006066770.094
homeostatic processGO:00425923310.094
response to estrogenGO:00436272320.093
cellular response to oxygen containing compoundGO:19017013860.093
single organism catabolic processGO:00447122830.093
blood circulationGO:00080151830.092
response to vitaminGO:00332731310.092
vitamin d3 metabolic processGO:007064020.090
hormone metabolic processGO:0042445690.089
vasoconstrictionGO:0042310540.088
reproductive processGO:00224143720.087
response to toxic substanceGO:00096361330.086
secondary metabolite catabolic processGO:009048710.086
apoptotic processGO:00069153810.083
cellular response to glucocorticoid stimulusGO:0071385680.083
xenobiotic metabolic processGO:0006805190.083
naphthalene metabolic processGO:001893120.082
vitamin biosynthetic processGO:000911030.082
regenerationGO:00310991630.082
trichloroethylene metabolic processGO:001897910.079
cofactor metabolic processGO:0051186950.079
positive regulation of cellular biosynthetic processGO:00313282950.078
long chain fatty acid metabolic processGO:0001676320.077
neurological system processGO:00508772190.077
cellular ketone metabolic processGO:0042180510.076
cellular response to hormone stimulusGO:00328702470.076
vitamin d metabolic processGO:004235940.076
negative regulation of serine type peptidase activityGO:190257210.076
cellular response to stressGO:00335542690.075
response to dexamethasoneGO:0071548490.074
hepaticobiliary system developmentGO:0061008900.074
cellular response to endogenous stimulusGO:00714953770.072
catecholamine transportGO:0051937370.071
ion transmembrane transportGO:00342203650.068
response to temperature stimulusGO:0009266940.068
negative regulation of metabolic processGO:00098923310.068
fatty acid biosynthetic processGO:0006633330.068
amine transportGO:0015837570.068
regulation of cell proliferationGO:00421273590.068
phenol containing compound metabolic processGO:0018958300.066
fatty acid transportGO:0015908250.065
response to carbohydrateGO:00097431830.065
arachidonic acid metabolic processGO:0019369200.064
vitamin d biosynthetic processGO:004236820.063
positive regulation of peptide hormone secretionGO:0090277500.063
regulation of rna biosynthetic processGO:20011413810.063
response to cadmium ionGO:0046686350.063
diterpenoid metabolic processGO:0016101330.062
response to ddtGO:004668010.061
cation transportGO:00068123820.061
demethylationGO:007098870.061
circulatory system processGO:00030131830.060
cellular response to nitrogen compoundGO:19016992100.058
macromolecular complex assemblyGO:00650032730.057
aromatic compound catabolic processGO:00194391680.057
regulation of amine transportGO:0051952540.057
response to ethanolGO:00454711620.057
transmembrane transportGO:00550854120.057
xenobiotic catabolic processGO:004217870.057
regulation of programmed cell deathGO:00430673410.056
regulation of secretion by cellGO:19035302080.056
oligopeptide transportGO:000685740.056
macromolecular complex subunit organizationGO:00439333390.055
alcohol biosynthetic processGO:0046165380.055
regulation of lipid metabolic processGO:0019216680.054
c21 steroid hormone biosynthetic processGO:0006700100.054
cellular response to ketoneGO:1901655510.054
response to alkaloidGO:00432791320.053
drug transportGO:0015893180.053
response to lipopolysaccharideGO:00324961910.053
amide transportGO:00428861050.052
response to transition metal nanoparticleGO:19902671220.052
regulation of response to woundingGO:1903034690.051
coenzyme metabolic processGO:0006732860.051
regulation of anatomical structure sizeGO:00900661350.051
cellular modified amino acid metabolic processGO:0006575610.050
acylglycerol metabolic processGO:0006639210.050
response to insulinGO:00328681330.050
negative regulation of macromolecule metabolic processGO:00106052600.050
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.050
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.049
gland developmentGO:00487321550.049
cellular response to alcoholGO:0097306870.049
response to corticosteroneGO:0051412400.048
c21 steroid hormone metabolic processGO:0008207140.047
regulation of anion transportGO:0044070430.047
sexual reproductionGO:00199531480.047
inflammatory responseGO:00069541500.046
cellular component assemblyGO:00226073600.046
response to vitamin dGO:0033280340.046
reactive oxygen species metabolic processGO:0072593370.046
positive regulation of signalingGO:00230562700.045
negative regulation of cell proliferationGO:00082851190.045
programmed cell deathGO:00125013920.045
regulation of peptide transportGO:0090087870.044
positive regulation of biosynthetic processGO:00098913190.044
nicotine metabolic processGO:001893310.044
positive regulation of nitrogen compound metabolic processGO:00511733340.044
biphenyl metabolic processGO:0018879100.043
growthGO:00400071650.043
smooth muscle cell proliferationGO:0048659770.043
cellular response to lipidGO:00713962010.042
positive regulation of cell proliferationGO:00082842490.042
neutral lipid metabolic processGO:0006638210.042
organ regenerationGO:00311001010.041
regulation of serine type peptidase activityGO:190257110.041
positive regulation of cellular component organizationGO:00511302000.041
organic cyclic compound catabolic processGO:19013611750.040
response to mercury ionGO:0046689150.039
vitamin d receptor signaling pathwayGO:007056110.039
triglyceride metabolic processGO:0006641210.039
regulation of growthGO:00400081050.039
immune responseGO:00069551040.039
cellular chemical homeostasisGO:00550822470.038
signal releaseGO:00230611450.038
behavioral response to nicotineGO:003509520.038
regulation of cellular localizationGO:00603412630.038
response to cytokineGO:00340972150.038
artery smooth muscle contractionGO:001482440.038
modified amino acid transportGO:0072337120.038
positive regulation of blood circulationGO:1903524650.038
monoamine transportGO:0015844430.037
regulation of catalytic activityGO:00507903040.037
response to extracellular stimulusGO:00099913800.037
cellular response to peptide hormone stimulusGO:00713751200.037
regulation of multicellular organismal developmentGO:20000263760.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
lipid catabolic processGO:0016042460.037
positive regulation of extracellular matrix organizationGO:190305540.037
regulation of amino acid transportGO:0051955250.037
regulation of apoptotic processGO:00429813350.036
anatomical structure morphogenesisGO:00096532980.036
neuron neuron synaptic transmissionGO:0007270600.036
muscle system processGO:00030121150.036
negative regulation of response to woundingGO:1903035230.036
cellular response to peptideGO:19016531330.036
regulation of response to external stimulusGO:00321011060.035
response to methanolGO:003398610.035
alpha amino acid metabolic processGO:1901605710.035
androgen biosynthetic processGO:0006702100.034
organonitrogen compound catabolic processGO:19015651790.034
naphthalene containing compound metabolic processGO:009042020.034
angiotensin mediated drinking behaviorGO:000305120.034
sulfur compound metabolic processGO:0006790700.033
positive regulation of gene expressionGO:00106282440.033
regulation of cellular amine metabolic processGO:003323880.033
regulation of norepinephrine secretionGO:0014061150.032
regulation of response to stressGO:00801341260.032
response to campGO:0051591910.032
cellular component biogenesisGO:00440853680.032
positive regulation of nervous system developmentGO:00519621780.031
negative regulation of molecular functionGO:00440921330.031
intestinal absorptionGO:005089230.031
protein oligomerizationGO:00512591910.031
stress activated protein kinase signaling cascadeGO:0031098370.031
transcription dna templatedGO:00063513770.031
ovulationGO:0030728170.030
response to hexoseGO:00097461440.030
defecationGO:003042110.030
regulation of cellular ketone metabolic processGO:0010565270.030
macromolecule localizationGO:00330362520.030
response to retinoic acidGO:0032526630.030
pyridine containing compound metabolic processGO:0072524320.030
positive regulation of cell differentiationGO:00455972170.030
response to external biotic stimulusGO:00432072210.030
catecholamine secretionGO:0050432330.029
placenta developmentGO:0001890220.029
tonic smooth muscle contractionGO:001482040.029
peptide transportGO:0015833970.029
response to nutrient levelsGO:00316673700.029
norepinephrine secretionGO:0048243160.029
response to vitamin aGO:0033189360.029
leydig cell differentiationGO:003332780.029
regulation of nervous system developmentGO:00519602640.029
developmental process involved in reproductionGO:00030061590.028
response to activityGO:0014823730.028
positive regulation of extracellular matrix constituent secretionGO:000333120.028
negative regulation of catalytic activityGO:00430861030.028
regulation of lipid biosynthetic processGO:0046890380.028
reproductive structure developmentGO:00486081280.028
positive regulation of secretionGO:00510471400.028
regulation of peptide secretionGO:0002791820.028
intracellular signal transductionGO:00355563140.028
regulation of molecular functionGO:00650093980.027
organic hydroxy compound transportGO:0015850770.027
negative regulation of gene expressionGO:00106291990.027
positive regulation of cell developmentGO:00107201760.027
developmental growthGO:00485891000.027
regulation of defense responseGO:0031347680.027
regulation of cell developmentGO:00602842630.027
aromatic amino acid family catabolic processGO:000907470.027
androgen metabolic processGO:0008209140.027
positive regulation of developmental processGO:00510942830.027
cellular response to steroid hormone stimulusGO:0071383930.027
glycerolipid metabolic processGO:0046486670.027
regulation of system processGO:00440572080.027
sterol homeostasisGO:005509230.027
cellular nitrogen compound catabolic processGO:00442701630.027
stress activated mapk cascadeGO:0051403350.026
secretion by cellGO:00329402480.026
response to woundingGO:00096112540.026
protein complex biogenesisGO:00702712630.026
regulation of blood circulationGO:19035221100.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
glycogen metabolic processGO:0005977230.026
regulation of neurological system processGO:0031644430.026
cellular homeostasisGO:00197252520.025
regulation of epithelial cell proliferationGO:0050678490.025
transmission of nerve impulseGO:0019226420.025
negative regulation of multicellular organismal processGO:00512412030.025
response to radiationGO:00093141370.025
response to decreased oxygen levelsGO:00362932370.025
positive regulation of cell deathGO:00109421840.025
peptide hormone secretionGO:0030072840.025
amine metabolic processGO:0009308380.025
negative regulation of cell communicationGO:00106481580.025
extracellular matrix constituent secretionGO:007027840.025
organophosphate metabolic processGO:00196373700.025
ribonucleotide metabolic processGO:00092592310.025
negative regulation of pancreatic stellate cell proliferationGO:200023010.025
response to mineralocorticoidGO:0051385490.025
regulation of synaptic transmissionGO:00508041410.025
negative regulation of protein metabolic processGO:00512481140.025
negative regulation of response to stimulusGO:00485851550.024
muscle cell proliferationGO:0033002840.024
response to monosaccharideGO:00342841590.024
peptide secretionGO:0002790860.024
benzene containing compound metabolic processGO:0042537220.024
response to glucoseGO:00097491360.024
retinoid metabolic processGO:0001523240.024
response to oxygen levelsGO:00704822650.024
regulation of systemic arterial blood pressureGO:0003073300.024
vitamin a metabolic processGO:000677620.023
regulation of ion transportGO:00432692450.023
regulation of cell differentiationGO:00455953200.023
negative regulation of response to external stimulusGO:0032102370.023
negative regulation of developmental processGO:00510931250.023
regulation of inflammatory responseGO:0050727480.023
positive regulation of programmed cell deathGO:00430681570.023
protein complex assemblyGO:00064612630.023
cellular component movementGO:00069282480.023
cell projection organizationGO:00300303020.023
single organism carbohydrate metabolic processGO:00447231180.023
cholesterol homeostasisGO:004263230.022
wound healingGO:00420601220.022
bile acid and bile salt transportGO:0015721120.022
second messenger mediated signalingGO:0019932510.022
response to chromateGO:004668730.022
regulation of immune responseGO:0050776550.022
regulation of serine type endopeptidase activityGO:190000310.022
reactive nitrogen species metabolic processGO:200105710.022
positive regulation of insulin secretionGO:0032024360.022
rna biosynthetic processGO:00327743800.021
negative regulation of serine type endopeptidase activityGO:190000410.021
tissue developmentGO:00098882520.021
regulation of hormone secretionGO:00468831060.021
gonad developmentGO:00084061040.021
defense response to gram negative bacteriumGO:005082930.021
steroid catabolic processGO:000670650.021
regulation of protein maturationGO:1903317500.021
regulation of rna metabolic processGO:00512523910.021
regulation of excretionGO:0044062210.021
cellular carbohydrate metabolic processGO:0044262720.021
lipid localizationGO:0010876620.021
regulation of insulin secretionGO:0050796650.021
gamete generationGO:00072761240.021
positive regulation of hemostasisGO:190004840.021
nucleobase containing small molecule metabolic processGO:00550863160.021
response to vitamin eGO:0033197240.020
catenin import into nucleusGO:003541110.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
reproductive system developmentGO:00614581280.020
insulin secretionGO:0030073690.020
ion homeostasisGO:00508012120.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
chemosensory behaviorGO:000763520.020
negative regulation of secretionGO:0051048820.020
regulation of organic acid transportGO:0032890350.020
regulation of protein processingGO:0070613500.019
regulation of cellular amino acid metabolic processGO:000652120.019
protein processingGO:0016485680.019
central nervous system developmentGO:00074173110.019
cellular amine metabolic processGO:0044106380.019
regulation of cellular component biogenesisGO:0044087860.019
icosanoid biosynthetic processGO:0046456180.019
glutathione transportGO:003463520.019
carbohydrate derivative catabolic processGO:19011361470.019
hormone secretionGO:00468791150.019
regulation of vasoconstrictionGO:0019229440.019
carbohydrate homeostasisGO:0033500750.019
regulation of fatty acid metabolic processGO:0019217180.019
metal ion transportGO:00300012890.019
immune system processGO:00023762040.018
purine containing compound metabolic processGO:00725212530.018
regulation of peptide hormone secretionGO:0090276800.018
neuron projection developmentGO:00311752730.018
medium chain fatty acid metabolic processGO:005179150.018
acetyl coa metabolic processGO:0006084170.018
proteolysisGO:00065081750.018
fatty acid oxidationGO:0019395290.018
synaptic transmissionGO:00072682350.018
response to muscle activity involved in regulation of muscle adaptationGO:001487320.018
transcription from rna polymerase ii promoterGO:00063662520.018
sensory perception of smellGO:000760850.018
monosaccharide metabolic processGO:0005996610.018
dna metabolic processGO:0006259960.018
positive regulation of organic acid transportGO:0032892220.018
cellular response to hexose stimulusGO:0071331650.018
angiogenesisGO:0001525530.018
secondary metabolic processGO:0019748150.018
phasic smooth muscle contractionGO:001482130.018
muscle tissue developmentGO:0060537580.018
female sex differentiationGO:0046660590.018
negative regulation of nervous system developmentGO:0051961790.017
positive regulation of neurogenesisGO:00507691650.017
regulation of secretionGO:00510462240.017
heart developmentGO:0007507720.017
negative regulation of signalingGO:00230571570.017
dicarboxylic acid transportGO:0006835340.017
positive regulation of amino acid transportGO:0051957130.017
cell cell signalingGO:00072673350.017
response to calcium ionGO:0051592590.017
response to ionizing radiationGO:0010212590.017
cell migrationGO:00164771970.017
tube developmentGO:0035295890.017
maternal process involved in female pregnancyGO:0060135380.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
folic acid containing compound metabolic processGO:0006760100.017
intracellular receptor signaling pathwayGO:0030522350.017
positive regulation of blood coagulationGO:003019440.016
positive regulation of mapk cascadeGO:0043410920.016
negative regulation of cellular biosynthetic processGO:00313271610.016
catechol containing compound metabolic processGO:0009712190.016
regulation of glutamate secretionGO:0014048170.016
organic cation transportGO:0015695110.016
protein maturationGO:0051604680.016
cellular response to external stimulusGO:00714961180.016
positive regulation of cellular amine metabolic processGO:003324030.016
regulation of protein serine threonine kinase activityGO:0071900640.016
signal transduction by phosphorylationGO:00230141440.016
phenylpropanoid metabolic processGO:000969850.016
cellular response to campGO:0071320260.016
cellular response to oxidative stressGO:0034599760.016
response to nicotineGO:0035094510.016
carbohydrate metabolic processGO:00059751300.016
polyol biosynthetic processGO:0046173130.016
cell motilityGO:00488702020.016
ovulation cycleGO:0042698670.015
tetrapyrrole metabolic processGO:0033013110.015
regulation of anatomical structure morphogenesisGO:00226031410.015
regulation of angiogenesisGO:0045765390.015
glycosyl compound metabolic processGO:19016571820.015
4 nitrophenol metabolic processGO:001896010.015
negative regulation of cellular protein metabolic processGO:00322691060.015
regulation of hydrolase activityGO:00513361430.015
response to fatty acidGO:0070542650.015
lipid storageGO:001991510.015
regulation of cellular component organizationGO:00511283680.015
nucleic acid templated transcriptionGO:00976593790.015
positive regulation of cellular component biogenesisGO:0044089550.015
lipid oxidationGO:0034440300.015
dicarboxylic acid metabolic processGO:0043648420.015
response to increased oxygen levelsGO:0036296450.015
carbohydrate derivative metabolic processGO:19011353460.015
brain renin angiotensin systemGO:000203530.015
bile acid biosynthetic processGO:000669930.015
sex differentiationGO:00075481130.015
protein complex subunit organizationGO:00718223020.015
circadian rhythmGO:0007623880.015
macrophage chemotaxisGO:004824620.015
response to mechanical stimulusGO:00096121340.014
long chain fatty acid transportGO:0015909140.014
synaptic transmission glutamatergicGO:0035249330.014
protein activation cascadeGO:0072376120.014
cardiovascular system developmentGO:00723581340.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
purine ribonucleoside metabolic processGO:00461281680.014
regulation of immune system processGO:00026821230.014
digestive tract developmentGO:0048565390.014
regulation of reactive oxygen species biosynthetic processGO:190342650.014
response to fungicideGO:0060992200.014
positive regulation of apoptotic processGO:00430651540.014
organonitrogen compound biosynthetic processGO:19015661670.014
response to growth factorGO:00708481890.014
rna metabolic processGO:00160704060.014
sensory perceptionGO:00076001010.014
response to antibioticGO:0046677390.014

Abcb11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hypertensionDOID:1076300.289
artery diseaseDOID:005082800.289
cardiovascular system diseaseDOID:128700.289
vascular diseaseDOID:17800.289
disease of anatomical entityDOID:700.289
essential hypertensionDOID:1082500.118
disease of metabolismDOID:001466700.040
nervous system diseaseDOID:86300.024
inherited metabolic disorderDOID:65500.018