Rattus norvegicus

30 known processes

Brca1

breast cancer 1

Brca1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.276
developmental process involved in reproductionGO:00030061590.264
response to other organismGO:00517072200.251
sex differentiationGO:00075481130.140
programmed cell deathGO:00125013920.133
Human
cellular response to oxygen containing compoundGO:19017013860.129
Human
organic acid metabolic processGO:00060822920.123
Human
multicellular organism reproductionGO:00325042330.123
cell projection organizationGO:00300303020.119
positive regulation of rna metabolic processGO:00512542030.117
Human Mouse
reproductive processGO:00224143720.109
cellular response to organonitrogen compoundGO:00714171970.104
Human
cellular amino acid metabolic processGO:00065201070.100
reproductive system developmentGO:00614581280.096
protein complex assemblyGO:00064612630.094
response to nutrient levelsGO:00316673700.093
positive regulation of cell communicationGO:00106472710.093
neuron developmentGO:00486662860.088
negative regulation of cellular component organizationGO:0051129830.085
Human Mouse
response to corticosteroidGO:00319602350.085
response to external biotic stimulusGO:00432072210.084
transcription from rna polymerase ii promoterGO:00063662520.080
Human Mouse
neuron projection developmentGO:00311752730.080
central nervous system developmentGO:00074173110.076
cell cell signalingGO:00072673350.075
cellular response to lipidGO:00713962010.075
regulation of transcription dna templatedGO:00063553740.075
Human Mouse
reproductive structure developmentGO:00486081280.074
regulation of transcription from rna polymerase ii promoterGO:00063572340.073
Human Mouse
macromolecular complex assemblyGO:00650032730.069
hormone transportGO:00099141210.069
oxoacid metabolic processGO:00434362900.067
Human
positive regulation of phosphorus metabolic processGO:00105622620.067
response to organophosphorusGO:00466831020.067
response to lipopolysaccharideGO:00324961910.067
regulation of rna metabolic processGO:00512523910.067
Human Mouse
positive regulation of cellular biosynthetic processGO:00313282950.066
Human Mouse
single organism reproductive processGO:00447022970.065
rhythmic processGO:00485111560.064
organ regenerationGO:00311001010.064
intracellular signal transductionGO:00355563140.064
Human
response to woundingGO:00096112540.061
transcription dna templatedGO:00063513770.061
Human Mouse
positive regulation of rna biosynthetic processGO:19026801970.061
Human Mouse
regulation of molecular functionGO:00650093980.060
positive regulation of macromolecule biosynthetic processGO:00105572470.060
Human Mouse
positive regulation of multicellular organismal processGO:00512403870.060
Human
regulation of rna biosynthetic processGO:20011413810.059
Human Mouse
cellular response to stressGO:00335542690.059
Human Mouse
cellular amine metabolic processGO:0044106380.059
nucleic acid templated transcriptionGO:00976593790.059
Human Mouse
positive regulation of biosynthetic processGO:00098913190.057
Human Mouse
cellular response to endogenous stimulusGO:00714953770.054
Human
regulation of nucleic acid templated transcriptionGO:19035063800.054
Human Mouse
regenerationGO:00310991630.054
reproductionGO:00000032450.052
protein complex biogenesisGO:00702712630.051
cellular component assemblyGO:00226073600.051
regulation of cell differentiationGO:00455953200.050
regulation of cell developmentGO:00602842630.050
positive regulation of phosphate metabolic processGO:00459372620.049
response to inorganic substanceGO:00100353770.049
response to growth factorGO:00708481890.049
regulation of neuron differentiationGO:00456642080.049
response to extracellular stimulusGO:00099913800.048
tissue developmentGO:00098882520.048
protein oligomerizationGO:00512591910.047
positive regulation of gene expressionGO:00106282440.047
Human Mouse
negative regulation of developmental processGO:00510931250.047
biological adhesionGO:00226101100.047
regulation of cellular amino acid metabolic processGO:000652120.046
female sex differentiationGO:0046660590.045
negative regulation of multicellular organismal processGO:00512412030.045
regulation of neurogenesisGO:00507672470.045
regulation of cell projection organizationGO:00313441750.044
agingGO:00075682410.044
cellular response to growth factor stimulusGO:00713631620.043
positive regulation of nitrogen compound metabolic processGO:00511733340.043
Human Mouse
response to biotic stimulusGO:00096072260.043
response to transition metal nanoparticleGO:19902671220.042
carboxylic acid metabolic processGO:00197522890.042
Human
gonad developmentGO:00084061040.041
response to bacteriumGO:00096172000.041
cell adhesionGO:00071551100.041
regulation of apoptotic processGO:00429813350.041
Human
carbohydrate derivative biosynthetic processGO:19011371240.041
negative regulation of rna metabolic processGO:00512531230.040
Human
positive regulation of nucleic acid templated transcriptionGO:19035081970.040
Human Mouse
response to oxidative stressGO:00069791860.040
response to metal ionGO:00100382530.040
regulation of phosphorylationGO:00423252480.040
wound healingGO:00420601220.039
head developmentGO:00603222470.039
response to carbohydrateGO:00097431830.039
peptidyl tyrosine modificationGO:0018212720.038
development of primary sexual characteristicsGO:00451371070.038
multicellular organismal reproductive processGO:00486092330.038
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
Human Mouse
cellular response to oxidative stressGO:0034599760.038
regulation of mapk cascadeGO:00434081160.037
cellular response to nitrogen compoundGO:19016992100.036
Human
response to radiationGO:00093141370.036
Human
negative regulation of metabolic processGO:00098923310.036
Human Mouse
positive regulation of developmental processGO:00510942830.036
Human
cellular catabolic processGO:00442482950.036
neurological system processGO:00508772190.036
coenzyme metabolic processGO:0006732860.036
amine metabolic processGO:0009308380.035
response to purine containing compoundGO:00140741260.035
regulation of signal transductionGO:00099663180.035
Human
response to molecule of bacterial originGO:00022371940.035
response to monosaccharideGO:00342841590.034
rna metabolic processGO:00160704060.034
Human Mouse
response to estrogenGO:00436272320.034
cell morphogenesis involved in neuron differentiationGO:00486671060.034
neuron fate commitmentGO:004866340.034
response to glucoseGO:00097491360.033
neuron projection morphogenesisGO:00488121220.033
mapk cascadeGO:00001651400.033
regulation of neuron projection developmentGO:00109751610.032
negative regulation of cell differentiationGO:0045596990.032
positive regulation of cell developmentGO:00107201760.032
cellular response to peptide hormone stimulusGO:00713751200.032
cell morphogenesisGO:00009021420.032
embryonic pattern specificationGO:000988010.031
female gonad developmentGO:0008585530.031
regulation of system processGO:00440572080.031
peptidyl amino acid modificationGO:00181931260.031
Human Mouse
positive regulation of neuron differentiationGO:00456661260.031
regulation of phosphate metabolic processGO:00192203490.031
negative regulation of cell deathGO:00605482290.031
Human
hormone secretionGO:00468791150.031
regulation of multicellular organismal developmentGO:20000263760.031
Human
gland developmentGO:00487321550.030
defense responseGO:00069521940.030
rna biosynthetic processGO:00327743800.030
Human Mouse
cellular component biogenesisGO:00440853680.030
regulation of neuron apoptotic processGO:0043523830.029
protein phosphorylationGO:00064683450.029
behaviorGO:00076102050.029
nucleotide biosynthetic processGO:0009165980.029
cell part morphogenesisGO:00329901230.029
negative regulation of gene expressionGO:00106291990.029
Human
liver developmentGO:0001889900.028
cell type specific apoptotic processGO:00972851340.028
chemical homeostasisGO:00488782920.028
glucose homeostasisGO:0042593750.028
anterior posterior pattern specificationGO:000995210.028
immune system processGO:00023762040.028
negative regulation of cellular metabolic processGO:00313242810.027
Human Mouse
positive regulation of neurogenesisGO:00507691650.027
pteridine containing compound metabolic processGO:0042558140.027
regulation of hormone levelsGO:00108171870.027
single organism behaviorGO:00447081300.027
multi organism reproductive processGO:00447032620.027
cellular response to peptideGO:19016531330.027
tetrahydrofolate metabolic processGO:004665390.026
macromolecular complex subunit organizationGO:00439333390.026
Human Mouse
signal releaseGO:00230611450.026
response to ketoneGO:19016541820.026
t cell activationGO:0042110290.026
response to temperature stimulusGO:0009266940.026
macromolecule localizationGO:00330362520.025
negative regulation of neurogenesisGO:0050768780.025
folic acid containing compound metabolic processGO:0006760100.025
cofactor metabolic processGO:0051186950.025
striated muscle tissue developmentGO:0014706580.025
regulation of cellular amine metabolic processGO:003323880.025
protein complex subunit organizationGO:00718223020.025
nucleoside phosphate metabolic processGO:00067532830.025
apoptotic processGO:00069153810.025
Human
cellular ketone metabolic processGO:0042180510.024
Human
organelle organizationGO:00069962660.024
Human Mouse
ion homeostasisGO:00508012120.024
nucleobase containing small molecule metabolic processGO:00550863160.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
Human
positive regulation of cellular amino acid metabolic processGO:004576410.024
positive regulation of response to stimulusGO:00485842850.024
Human
catabolic processGO:00090563510.023
regulation of dna metabolic processGO:0051052600.023
Human Mouse
cation transportGO:00068123820.023
regulation of body fluid levelsGO:0050878900.023
response to reactive oxygen speciesGO:00003021200.023
negative regulation of apoptotic processGO:00430661810.023
Human
regulation of nervous system developmentGO:00519602640.023
positive regulation of intracellular signal transductionGO:19025331380.023
homeostatic processGO:00425923310.023
sexual reproductionGO:00199531480.023
gamete generationGO:00072761240.023
response to glucocorticoidGO:00513842230.023
alpha amino acid metabolic processGO:1901605710.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
Human
regulation of cellular ketone metabolic processGO:0010565270.023
Human
regulation of kinase activityGO:00435491170.022
regulation of phosphorus metabolic processGO:00511743490.022
positive regulation of cellular protein metabolic processGO:00322701670.022
Human Mouse
growthGO:00400071650.022
response to peptideGO:19016522920.022
positive regulation of mapk cascadeGO:0043410920.022
metaphase anaphase transition of cell cycleGO:004478410.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.022
response to hydrogen peroxideGO:0042542890.022
nephric duct developmentGO:007217610.022
negative regulation of nervous system developmentGO:0051961790.021
negative regulation of macromolecule metabolic processGO:00106052600.021
Human Mouse
mitotic sister chromatid separationGO:005130610.021
axon developmentGO:0061564960.021
response to heatGO:0009408600.021
purine containing compound metabolic processGO:00725212530.021
positive regulation of apoptotic processGO:00430651540.021
gliogenesisGO:0042063930.020
dna metabolic processGO:0006259960.020
Human Mouse
positive regulation of protein phosphorylationGO:00019341350.020
regulation of protein modification processGO:00313991940.020
Human Mouse
positive regulation of signal transductionGO:00099671750.020
regulation of programmed cell deathGO:00430673410.020
Human
cofactor biosynthetic processGO:0051188280.019
positive regulation of protein metabolic processGO:00512471780.019
Human Mouse
positive regulation of cell deathGO:00109421840.019
gastrulationGO:000736920.019
cellular response to external stimulusGO:00714961180.019
regulation of cell morphogenesis involved in differentiationGO:0010769720.019
proteolysisGO:00065081750.019
regulation of cellular protein metabolic processGO:00322682670.019
Human Mouse
response to amino acidGO:0043200750.019
glial cell differentiationGO:0010001650.019
positive regulation of cellular component organizationGO:00511302000.019
Human Mouse
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
Human Mouse
salivary gland morphogenesisGO:000743510.018
positive regulation of transcription dna templatedGO:00458931970.018
Human Mouse
positive regulation of lipid kinase activityGO:009021820.018
localization of cellGO:00516742020.018
carbohydrate homeostasisGO:0033500750.018
positive regulation of neuron projection developmentGO:0010976990.018
cell projection morphogenesisGO:00488581230.018
ribonucleotide biosynthetic processGO:0009260850.018
regulation of intracellular signal transductionGO:19025312180.018
negative regulation of cell developmentGO:0010721820.018
neuron apoptotic processGO:0051402880.018
secretionGO:00469033070.018
peptidyl tyrosine phosphorylationGO:0018108720.018
positive regulation of phosphorylationGO:00423271770.018
carbohydrate metabolic processGO:00059751300.018
positive regulation of transportGO:00510502450.018
positive regulation of cellular amine metabolic processGO:003324030.017
response to alkaloidGO:00432791320.017
cell cycle checkpointGO:000007520.017
Human
response to estradiolGO:00323551640.017
organonitrogen compound biosynthetic processGO:19015661670.017
carbohydrate derivative metabolic processGO:19011353460.017
positive regulation of cell differentiationGO:00455972170.017
protein heterooligomerizationGO:0051291890.017
regulation of cell proliferationGO:00421273590.017
response to hexoseGO:00097461440.017
cellular homeostasisGO:00197252520.017
cellular component morphogenesisGO:00329891550.017
regulation of proteasomal protein catabolic processGO:006113640.017
positive regulation of molecular functionGO:00440932300.017
hematopoietic or lymphoid organ developmentGO:0048534360.016
male sex differentiationGO:0046661640.016
positive regulation of programmed cell deathGO:00430681570.016
response to cytokineGO:00340972150.016
Human
negative regulation of biosynthetic processGO:00098901680.016
Human
amide transportGO:00428861050.016
cellular response to glucose stimulusGO:0071333650.016
sensory perceptionGO:00076001010.016
positive regulation of neuron deathGO:1901216430.016
response to acid chemicalGO:00011012220.016
regulation of cellular localizationGO:00603412630.016
axis specificationGO:000979840.016
monosaccharide metabolic processGO:0005996610.016
cell morphogenesis involved in differentiationGO:00009041190.016
cellular response to steroid hormone stimulusGO:0071383930.015
cerebellar purkinje cell layer developmentGO:002168020.015
response to oxygen levelsGO:00704822650.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
regulation of membrane potentialGO:00423911100.015
olfactory learningGO:000835510.015
positive regulation of protein modification processGO:00314011420.015
Human Mouse
alpha amino acid biosynthetic processGO:1901607230.015
cellular chemical homeostasisGO:00550822470.015
cellular response to reactive oxygen speciesGO:0034614550.015
dendrite developmentGO:0016358720.015
regulation of metal ion transportGO:00109591180.015
regulation of cellular component organizationGO:00511283680.015
Human Mouse
ovulation cycle processGO:0022602500.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.014
purine containing compound biosynthetic processGO:0072522850.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
embryonic skeletal system developmentGO:004870630.014
regulation of protein phosphorylationGO:00019321830.014
single organism catabolic processGO:00447122830.014
negative regulation of neuron differentiationGO:0045665620.014
response to tumor necrosis factorGO:0034612560.014
Human
synaptic growth at neuromuscular junctionGO:005112410.014
small gtpase mediated signal transductionGO:0007264360.014
epithelium developmentGO:0060429960.014
anatomical structure morphogenesisGO:00096532980.014
Human
antral ovarian follicle growthGO:000154730.014
regulation of sister chromatid segregationGO:003304510.014
muscle structure developmentGO:0061061870.014
metanephric part of ureteric bud developmentGO:003550210.014
cardiac chamber developmentGO:000320510.014
protein localizationGO:00081041910.013
nitrogen compound transportGO:00717052290.013
negative regulation of molecular functionGO:00440921330.013
negative regulation of transportGO:00510511360.013
negative regulation of transcription dna templatedGO:00458921160.013
Human
ovulation cycleGO:0042698670.013
response to decreased oxygen levelsGO:00362932370.013
inorganic ion transmembrane transportGO:00986602290.013
response to ethanolGO:00454711620.013
secretion by cellGO:00329402480.013
regulation of protein kinase activityGO:00458591050.013
negative regulation of cellular biosynthetic processGO:00313271610.013
Human
ribose phosphate metabolic processGO:00196932350.013
cardiac conductionGO:006133720.013
regulation of peptide secretionGO:0002791820.013
regulation of catalytic activityGO:00507903040.013
regulation of mitotic sister chromatid separationGO:001096510.013
retinal ganglion cell axon guidanceGO:003129010.013
cellular response to organic cyclic compoundGO:00714072020.013
Human
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
Human
positive regulation of cell projection organizationGO:00313461110.013
negative regulation of signalingGO:00230571570.013
Human
negative regulation of phosphate metabolic processGO:0045936800.013
response to electrical stimulusGO:0051602560.013
organophosphate metabolic processGO:00196373700.013
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.013
negative regulation of cell cycle phase transitionGO:190198840.013
tube developmentGO:0035295890.012
hindbrain morphogenesisGO:002157520.012
cell activationGO:0001775970.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
cellular response to insulin stimulusGO:0032869810.012
muscle organ developmentGO:0007517500.012
mitotic spindle organizationGO:000705220.012
regulation of transferase activityGO:00513381230.012
nucleoside triphosphate metabolic processGO:00091411440.012
mammary gland developmentGO:0030879380.012
purine nucleotide metabolic processGO:00061632290.012
positive regulation of transferase activityGO:0051347810.012
negative regulation of catalytic activityGO:00430861030.012
chemosensory behaviorGO:000763520.012
regulation of synaptic transmissionGO:00508041410.012
heart morphogenesisGO:000300730.012
cellular response to hexose stimulusGO:0071331650.012
motor neuron axon guidanceGO:000804510.012
epithelial cell differentiationGO:0030855710.012
response to amineGO:0014075460.012
purine nucleoside metabolic processGO:00422781690.012
cellular response to extracellular stimulusGO:0031668730.012
fructose 2 6 bisphosphate metabolic processGO:000600320.012
cellular component movementGO:00069282480.012
response to zinc ionGO:0010043390.012
glucose metabolic processGO:0006006520.012
nucleoside phosphate biosynthetic processGO:19012931020.012
brain developmentGO:00074202470.011
olfactory behaviorGO:004204820.011
negative regulation of signal transductionGO:0009968830.011
Human
axonogenesisGO:0007409710.011
regulation of insulin secretionGO:0050796650.011
cytoplasmic transportGO:00164821150.011
inflammatory responseGO:00069541500.011
regulation of secretionGO:00510462240.011
dna integrity checkpointGO:003157020.011
Human
hexose metabolic processGO:0019318580.011
negative regulation of rna biosynthetic processGO:19026791180.011
Human
synaptic transmissionGO:00072682350.011
male gamete generationGO:0048232990.011
circulatory system processGO:00030131830.011
signal transduction by phosphorylationGO:00230141440.011
cellular response to hormone stimulusGO:00328702470.011
cellular protein complex assemblyGO:0043623440.011
cellular response to nutrient levelsGO:0031669600.011
cellular response to cytokine stimulusGO:00713451270.011
Human
response to campGO:0051591910.011
single organism cell adhesionGO:0098602460.011
cellular response to carbohydrate stimulusGO:0071322720.011
cerebellar purkinje cell layer morphogenesisGO:002169210.011
positive regulation of peptide secretionGO:0002793520.011
spermatogenesisGO:0007283990.011
regulation of mitotic sister chromatid segregationGO:003304710.011
metaphase anaphase transition of mitotic cell cycleGO:000709110.011
negative regulation of neuron projection developmentGO:0010977460.011
positive regulation of nervous system developmentGO:00519621780.011
response to nutrientGO:00075842480.011
ribose phosphate biosynthetic processGO:0046390870.011
developmental growthGO:00485891000.011
glycosyl compound metabolic processGO:19016571820.011
salivary gland developmentGO:000743130.011
palate developmentGO:006002120.011
leukocyte cell cell adhesionGO:000715940.010
regulation of protein metabolic processGO:00512462890.010
Human Mouse
negative regulation of cellular amine metabolic processGO:003323930.010
circadian regulation of gene expressionGO:003292230.010
nucleotide metabolic processGO:00091172790.010
negative regulation of protein phosphorylationGO:0001933440.010
cell cycleGO:00070491010.010
Human Mouse
regulation of map kinase activityGO:0043405530.010
negative regulation of protein metabolic processGO:00512481140.010
Human Mouse
cellular response to acid chemicalGO:0071229750.010
regulation of organelle organizationGO:0033043800.010
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
Human
positive regulation of dendrite developmentGO:1900006350.010
negative regulation of programmed cell deathGO:00430691830.010
Human
cellular macromolecule localizationGO:00707271220.010
response to axon injuryGO:0048678590.010
spindle organizationGO:000705120.010

Brca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.059
Human
cancerDOID:16200.059
Human
organ system cancerDOID:005068600.029
Human
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
inherited metabolic disorderDOID:65500.018
disease of metabolismDOID:001466700.018
metal metabolism disorderDOID:89600.015
gastrointestinal system cancerDOID:311900.013
central nervous system diseaseDOID:33100.011