IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Aadac

arylacetamide deacetylase (esterase)

(Aliases: Aada)

Ensembl: ENSRNOG00000013950
Entrez: 57300
RGD: 631440
UniProtKB: Q9QZH8

Process Predictions
Disease Predictions

Aadac biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid metabolic process	GO:0019752	289	0.268
cofactor metabolic process	GO:0051186	95	0.171
cellular lipid metabolic process	GO:0044255	208	0.153	Mouse
organic anion transport	GO:0015711	132	0.131
fatty acid metabolic process	GO:0006631	99	0.130
organic acid metabolic process	GO:0006082	292	0.120
oxoacid metabolic process	GO:0043436	290	0.117
alpha amino acid metabolic process	GO:1901605	71	0.115
anion transport	GO:0006820	178	0.084
lipid metabolic process	GO:0006629	283	0.078	Mouse
coenzyme metabolic process	GO:0006732	86	0.073
cellular amino acid metabolic process	GO:0006520	107	0.069
response to metal ion	GO:0010038	253	0.067
organic acid transport	GO:0015849	116	0.064
intestinal absorption	GO:0050892	3	0.063
halogenated hydrocarbon metabolic process	GO:0042197	4	0.061
aromatic amino acid family metabolic process	GO:0009072	9	0.057
response to ethanol	GO:0045471	162	0.053
response to peptide	GO:1901652	292	0.049
organophosphate metabolic process	GO:0019637	370	0.048
isoprenoid metabolic process	GO:0006720	45	0.044
small molecule biosynthetic process	GO:0044283	124	0.043
organic hydroxy compound metabolic process	GO:1901615	115	0.041
aging	GO:0007568	241	0.040
nitrogen cycle metabolic process	GO:0071941	5	0.039
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.039
aromatic amino acid family catabolic process	GO:0009074	7	0.039
response to insulin	GO:0032868	133	0.038
carboxylic acid transport	GO:0046942	115	0.037
multi organism reproductive process	GO:0044703	262	0.036
naphthalene metabolic process	GO:0018931	2	0.036
response to inorganic substance	GO:0010035	377	0.035
cellular catabolic process	GO:0044248	295	0.034	Mouse
single organism biosynthetic process	GO:0044711	342	0.034
monocarboxylic acid metabolic process	GO:0032787	152	0.033
alpha amino acid catabolic process	GO:1901606	20	0.032
response to ketone	GO:1901654	182	0.032
cellular response to fluid shear stress	GO:0071498	4	0.032
organic acid biosynthetic process	GO:0016053	83	0.032
reproductive process	GO:0022414	372	0.032
carboxylic acid catabolic process	GO:0046395	49	0.031
response to acid chemical	GO:0001101	222	0.031
cellular hormone metabolic process	GO:0034754	49	0.031
cellular response to external stimulus	GO:0071496	118	0.031
response to peptide hormone	GO:0043434	278	0.030
indolalkylamine metabolic process	GO:0006586	5	0.029
pyridine containing compound metabolic process	GO:0072524	32	0.029
lipid biosynthetic process	GO:0008610	128	0.028
cellular amino acid catabolic process	GO:0009063	21	0.028
cellular amine metabolic process	GO:0044106	38	0.027
amine metabolic process	GO:0009308	38	0.027
multicellular organismal reproductive process	GO:0048609	233	0.026
response to nutrient levels	GO:0031667	370	0.025
transmembrane transport	GO:0055085	412	0.025
organic acid catabolic process	GO:0016054	49	0.024
response to extracellular stimulus	GO:0009991	380	0.024
monovalent inorganic cation transport	GO:0015672	172	0.024
response to transition metal nanoparticle	GO:1990267	122	0.024
response to zinc ion	GO:0010043	39	0.023
regulation of hormone levels	GO:0010817	187	0.023
cellular ketone metabolic process	GO:0042180	51	0.023
steroid metabolic process	GO:0008202	73	0.023
protein homotrimerization	GO:0070207	15	0.023
drug catabolic process	GO:0042737	1	0.022
catabolic process	GO:0009056	351	0.022	Mouse
naphthalene containing compound metabolic process	GO:0090420	2	0.022
protein homooligomerization	GO:0051260	91	0.022
response to oxidative stress	GO:0006979	186	0.022
response to insecticide	GO:0017085	21	0.022
cellular modified amino acid metabolic process	GO:0006575	61	0.021
organic hydroxy compound biosynthetic process	GO:1901617	51	0.021
nicotinamide nucleotide metabolic process	GO:0046496	28	0.021
response to hypoxia	GO:0001666	231	0.020
monocarboxylic acid transport	GO:0015718	52	0.020
cellular component assembly	GO:0022607	360	0.020
nucleobase containing small molecule metabolic process	GO:0055086	316	0.020
synaptic growth at neuromuscular junction	GO:0051124	1	0.020
liver development	GO:0001889	90	0.020
oxidation reduction process	GO:0055114	304	0.020
inner medullary collecting duct development	GO:0072061	1	0.020
cellular response to stress	GO:0033554	269	0.019
cellular component biogenesis	GO:0044085	368	0.019
single organism catabolic process	GO:0044712	283	0.019	Mouse
response to corticosteroid	GO:0031960	235	0.019
amino acid transport	GO:0006865	70	0.019
urea cycle	GO:0000050	5	0.019
terpenoid metabolic process	GO:0006721	37	0.019
lipid localization	GO:0010876	62	0.018
anion transmembrane transport	GO:0098656	77	0.018
regulation of mrna splicing via spliceosome	GO:0048024	3	0.018
macromolecule localization	GO:0033036	252	0.018
reproduction	GO:0000003	245	0.018
response to decreased oxygen levels	GO:0036293	237	0.018
response to oxygen levels	GO:0070482	265	0.018
serine family amino acid metabolic process	GO:0009069	12	0.018
phenol containing compound metabolic process	GO:0018958	30	0.018
hepaticobiliary system development	GO:0061008	90	0.017
cellular response to oxygen containing compound	GO:1901701	386	0.017
response to cadmium ion	GO:0046686	35	0.017
circadian rhythm	GO:0007623	88	0.017
xenobiotic metabolic process	GO:0006805	19	0.017
regulation of cellular amino acid metabolic process	GO:0006521	2	0.017
response to nitrosative stress	GO:0051409	2	0.016
chromosome segregation	GO:0007059	2	0.016
response to nicotine	GO:0035094	51	0.016
homeostatic process	GO:0042592	331	0.016
regulation of cellular amine metabolic process	GO:0033238	8	0.016
response to estrogen	GO:0043627	232	0.016
response to glucocorticoid	GO:0051384	223	0.016
single organism organelle organization	GO:1902589	180	0.016
macromolecular complex assembly	GO:0065003	273	0.016
positive regulation of cell projection organization	GO:0031346	111	0.016
sorbitol metabolic process	GO:0006060	1	0.015
action potential	GO:0001508	54	0.015
response to alkaloid	GO:0043279	132	0.015
hormone metabolic process	GO:0042445	69	0.015
organonitrogen compound biosynthetic process	GO:1901566	167	0.014
response to xenobiotic stimulus	GO:0009410	23	0.014
response to molecule of bacterial origin	GO:0002237	194	0.014
positive regulation of homeostatic process	GO:0032846	49	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
xenobiotic catabolic process	GO:0042178	7	0.014
regulation of cell projection organization	GO:0031344	175	0.014
ion transmembrane transport	GO:0034220	365	0.014
acrosome assembly	GO:0001675	3	0.014
regulation of response to stress	GO:0080134	126	0.014
diterpenoid metabolic process	GO:0016101	33	0.014
organelle organization	GO:0006996	266	0.014
regulation of cellular component organization	GO:0051128	368	0.013
acetyl coa metabolic process	GO:0006084	17	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
regulation of neuron projection development	GO:0010975	161	0.013
dicarboxylic acid metabolic process	GO:0043648	42	0.013
alpha amino acid biosynthetic process	GO:1901607	23	0.013
pteridine containing compound metabolic process	GO:0042558	14	0.013
single organism behavior	GO:0044708	130	0.013
behavior	GO:0007610	205	0.013
organic substance catabolic process	GO:1901575	316	0.013	Mouse
nicotinamide nucleotide biosynthetic process	GO:0019359	2	0.013
cellular response to extracellular stimulus	GO:0031668	73	0.013
necroptotic process	GO:0070266	2	0.013
lipid storage	GO:0019915	1	0.013
cation transport	GO:0006812	382	0.013
reactive oxygen species metabolic process	GO:0072593	37	0.013
sexual reproduction	GO:0019953	148	0.013
positive regulation of cellular amine metabolic process	GO:0033240	3	0.013
response to vitamin	GO:0033273	131	0.013
heterocycle catabolic process	GO:0046700	167	0.013
macromolecular complex subunit organization	GO:0043933	339	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.012
response to nutrient	GO:0007584	248	0.012
dicarboxylic acid transport	GO:0006835	34	0.012
protein oligomerization	GO:0051259	191	0.012
chemical homeostasis	GO:0048878	292	0.012
cofactor biosynthetic process	GO:0051188	28	0.012
retinoid metabolic process	GO:0001523	24	0.012
response to corticosterone	GO:0051412	40	0.012
sorbitol biosynthetic process	GO:0006061	1	0.012
single organism reproductive process	GO:0044702	297	0.012
benzene containing compound metabolic process	GO:0042537	22	0.012
regulation of anatomical structure size	GO:0090066	135	0.011
sulfur compound metabolic process	GO:0006790	70	0.011
oligopeptide transport	GO:0006857	4	0.011
positive regulation of neuron projection development	GO:0010976	99	0.011
rhythmic process	GO:0048511	156	0.011
alkaloid metabolic process	GO:0009820	3	0.011
nucleoside phosphate metabolic process	GO:0006753	283	0.011
organophosphate biosynthetic process	GO:0090407	143	0.011
nicotine metabolic process	GO:0018933	1	0.011
steroid biosynthetic process	GO:0006694	48	0.011
retinal metabolic process	GO:0042574	3	0.011
circulatory system process	GO:0003013	183	0.011
folic acid containing compound metabolic process	GO:0006760	10	0.011
response to radiation	GO:0009314	137	0.011
regulation of synaptic plasticity	GO:0048167	70	0.011
reactive nitrogen species metabolic process	GO:2001057	1	0.011
carboxylic acid biosynthetic process	GO:0046394	83	0.011
protein complex assembly	GO:0006461	263	0.011
negative regulation of metabolic process	GO:0009892	331	0.011
tripeptide transport	GO:0042939	2	0.011
cation transmembrane transport	GO:0098655	263	0.011
alcohol metabolic process	GO:0006066	77	0.011
linoleic acid metabolic process	GO:0043651	4	0.011
cellular response to nutrient levels	GO:0031669	60	0.010
establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	1	0.010
lipid transport	GO:0006869	61	0.010
calcitriol biosynthetic process from calciol	GO:0036378	2	0.010
cellular response to metal ion	GO:0071248	55	0.010
g protein coupled receptor signaling pathway	GO:0007186	242	0.010
regulation of dendrite development	GO:0050773	59	0.010
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	3	0.010
epithelial cell proliferation involved in liver morphogenesis	GO:0072575	3	0.010
regulation of blood volume by renal aldosterone	GO:0002017	1	0.010
multicellular organism growth	GO:0035264	1	0.010
fatty acid transmembrane transport	GO:1902001	3	0.010
angiotensin mediated drinking behavior	GO:0003051	2	0.010
cell projection organization	GO:0030030	302	0.010

Aadac disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
cardiovascular system disease	DOID:1287	0.025
disease of anatomical entity	DOID:7	0.025
vascular disease	DOID:178	0.025
hypertension	DOID:10763	0.011
artery disease	DOID:0050828	0.011
essential hypertension	DOID:10825	0.011

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