Rattus norvegicus

84 known processes

Cd74

Cd74 molecule, major histocompatibility complex, class II invariant chain

(Aliases: INVG34)

Cd74 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.997
Mouse
antigen processing and presentation of peptide antigen via mhc class iiGO:000249510.995
Mouse
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000250410.993
Mouse
cellular response to ammonium ionGO:0071242170.990
negative regulation of t cell activationGO:005086870.985
Mouse
antigen processing and presentation of peptide antigenGO:004800220.984
Mouse
regulation of t cell proliferationGO:0042129170.955
t cell proliferationGO:0042098190.944
negative regulation of t cell proliferationGO:004213050.944
negative regulation of leukocyte proliferationGO:007066460.934
negative regulation of lymphocyte activationGO:0051250100.930
Mouse
regulation of t cell activationGO:0050863230.873
Mouse
immune system processGO:00023762040.853
Human Mouse
regulation of mononuclear cell proliferationGO:0032944260.836
Human
response to other organismGO:00517072200.828
cellular response to isoquinoline alkaloidGO:007131760.817
t cell activationGO:0042110290.817
Mouse
immunoglobulin mediated immune responseGO:001606440.809
Mouse
negative regulation of mononuclear cell proliferationGO:003294560.794
regulation of antigen processing and presentationGO:000257710.773
Mouse
b cell mediated immunityGO:001972440.729
Mouse
antigen processing and presentationGO:001988220.708
Mouse
cellular response to morphineGO:007131550.635
innate immune responseGO:0045087350.599
antigen processing and presentation of exogenous antigenGO:001988410.576
Mouse
regulation of cell proliferationGO:00421273590.569
Human
antigen processing and presentation of exogenous peptide antigenGO:000247810.556
Mouse
negative regulation of lymphocyte proliferationGO:005067260.551
cellular response to corticosteroid stimulusGO:0071384690.548
cellular response to organic cyclic compoundGO:00714072020.537
macromolecular complex assemblyGO:00650032730.510
Mouse
lymphocyte activationGO:0046649430.498
Human Mouse
negative regulation of immune system processGO:0002683390.458
Mouse
response to interferon gammaGO:0034341200.418
cellular response to dexamethasone stimulusGO:0071549360.393
programmed cell deathGO:00125013920.385
Human Mouse
response to corticosteroidGO:00319602350.380
immune responseGO:00069551040.378
Mouse
cell activationGO:0001775970.350
Human Mouse
response to dexamethasoneGO:0071548490.328
cellular response to endogenous stimulusGO:00714953770.327
response to symbiontGO:000960810.296
negative regulation of leukocyte activationGO:0002695140.293
Mouse
leukocyte activationGO:0045321760.279
Human Mouse
macromolecular complex subunit organizationGO:00439333390.273
Mouse
regulation of lymphocyte proliferationGO:0050670260.238
Human
lymphocyte proliferationGO:0046651290.223
Human
protein complex assemblyGO:00064612630.223
Mouse
regulation of cell activationGO:0050865500.223
Human Mouse
cellular response to cytokine stimulusGO:00713451270.220
Human Mouse
positive regulation of antigen processing and presentationGO:000257910.219
Mouse
response to cytokineGO:00340972150.218
Human Mouse
protein complex biogenesisGO:00702712630.215
Mouse
chemotaxisGO:0006935660.205
Mouse
regulation of leukocyte proliferationGO:0070663260.194
Human
hemopoiesisGO:0030097340.188
Mouse
cellular component assemblyGO:00226073600.188
Mouse
b cell differentiationGO:003018320.171
de novo protein foldingGO:000645820.165
Mouse
response to ammonium ionGO:0060359710.142
positive regulation of immune system processGO:0002684900.141
Human Mouse
regulation of adaptive immune responseGO:000281980.140
protein complex subunit organizationGO:00718223020.134
Mouse
regulation of immune system processGO:00026821230.115
Human Mouse
cellular response to stressGO:00335542690.113
Human Mouse
negative regulation of cell proliferationGO:00082851190.110
de novo posttranslational protein foldingGO:005108420.109
Mouse
mononuclear cell proliferationGO:0032943290.106
Human
cellular response to hormone stimulusGO:00328702470.105
cellular response to nitrogen compoundGO:19016992100.099
cellular protein complex assemblyGO:0043623440.099
cellular response to alcoholGO:0097306870.098
response to glucocorticoidGO:00513842230.088
regulation of t cell differentiationGO:004558070.087
Mouse
positive regulation of cell activationGO:0050867340.084
Human Mouse
response to external biotic stimulusGO:00432072210.081
response to ketoneGO:19016541820.080
leukocyte differentiationGO:0002521300.076
Mouse
cellular component biogenesisGO:00440853680.076
Mouse
response to biotic stimulusGO:00096072260.072
negative regulation of nitrogen compound metabolic processGO:00511721610.071
apoptotic processGO:00069153810.068
Human Mouse
response to fungusGO:000962080.066
cellular response to organonitrogen compoundGO:00714171970.065
leukocyte proliferationGO:0070661290.065
Human
response to hexoseGO:00097461440.060
positive regulation of cell proliferationGO:00082842490.059
Human
head developmentGO:00603222470.057
cellular response to steroid hormone stimulusGO:0071383930.053
regulation of programmed cell deathGO:00430673410.053
Human Mouse
cytoskeleton organizationGO:00070101110.052
negative regulation of apoptotic processGO:00430661810.051
Human Mouse
regulation of cellular ketone metabolic processGO:0010565270.050
cellular response to oxygen containing compoundGO:19017013860.049
response to inorganic substanceGO:00100353770.048
cellular response to lipidGO:00713962010.045
neuron projection developmentGO:00311752730.044
negative regulation of cellular metabolic processGO:00313242810.044
immune system developmentGO:0002520410.043
Mouse
cell junction maintenanceGO:003433110.042
cellular amino acid metabolic processGO:00065201070.041
cellular macromolecular complex assemblyGO:0034622580.041
cognitionGO:0050890920.040
cellular homeostasisGO:00197252520.039
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282280.037
defense responseGO:00069521940.036
Mouse
cellular amide metabolic processGO:0043603440.035
catabolic processGO:00090563510.035
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.034
chaperone mediated protein folding requiring cofactorGO:005108520.034
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
t helper 1 type immune responseGO:004208810.033
regulation of leukocyte activationGO:0002694450.033
Human Mouse
cell cell signalingGO:00072673350.033
response to isoquinoline alkaloidGO:0014072280.033
gland developmentGO:00487321550.032
response to starvationGO:0042594590.032
positive regulation of immunoglobulin productionGO:000263940.032
cellular response to starvationGO:0009267270.032
negative regulation of metabolic processGO:00098923310.032
positive regulation of lymphocyte differentiationGO:004562160.032
Mouse
negative regulation of cell developmentGO:0010721820.031
cellular ketone metabolic processGO:0042180510.031
response to estradiolGO:00323551640.030
negative regulation of phosphate metabolic processGO:0045936800.030
positive regulation of cell differentiationGO:00455972170.030
Mouse
cation transportGO:00068123820.029
organ regenerationGO:00311001010.029
brain developmentGO:00074202470.029
regulation of b cell mediated immunityGO:000271220.028
monovalent inorganic cation transportGO:00156721720.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282460.027
positive regulation of signalingGO:00230562700.027
regulation of neurogenesisGO:00507672470.027
regulation of cell differentiationGO:00455953200.027
Mouse
single organism catabolic processGO:00447122830.026
negative regulation of transportGO:00510511360.025
Human
positive regulation of cellular biosynthetic processGO:00313282950.025
negative regulation of biosynthetic processGO:00098901680.025
hematopoietic progenitor cell differentiationGO:000224420.024
positive regulation of leukocyte activationGO:0002696300.024
Human Mouse
cellular metal ion homeostasisGO:00068751720.024
cation homeostasisGO:00550801950.024
cellular protein catabolic processGO:0044257190.024
cell projection organizationGO:00300303020.023
regulation of homeostatic processGO:00328441010.023
Mouse
positive regulation of multicellular organismal processGO:00512403870.023
Mouse
response to peptide hormoneGO:00434342780.023
negative regulation of cellular biosynthetic processGO:00313271610.023
cellular catabolic processGO:00442482950.023
negative regulation of cell differentiationGO:0045596990.023
Mouse
organic substance catabolic processGO:19015753160.023
response to extracellular stimulusGO:00099913800.022
cell migrationGO:00164771970.022
Mouse
negative regulation of macromolecule metabolic processGO:00106052600.022
actin filament based processGO:0030029860.022
regulation of locomotionGO:00400121480.022
Mouse
response to morphineGO:0043278270.022
sodium ion transportGO:0006814820.022
regulation of cellular amino acid metabolic processGO:000652120.021
neuron differentiationGO:00301823680.021
regulatory t cell differentiationGO:004506620.021
regulation of cellular amine metabolic processGO:003323880.021
endocytosisGO:0006897840.021
cellular amine metabolic processGO:0044106380.020
negative regulation of protein metabolic processGO:00512481140.020
maintenance of locationGO:0051235170.020
ras protein signal transductionGO:0007265290.019
positive regulation of leukocyte differentiationGO:1902107130.019
Mouse
cytosolic calcium ion homeostasisGO:00514801400.019
carboxylic acid metabolic processGO:00197522890.019
Human
regulation of phosphorylationGO:00423252480.019
axis specificationGO:000979840.018
regulation of phosphate metabolic processGO:00192203490.018
positive regulation of t cell differentiationGO:004558260.018
Mouse
organelle organizationGO:00069962660.018
positive regulation of lymphocyte activationGO:0051251250.018
Human Mouse
negative regulation of neuron differentiationGO:0045665620.018
response to alkaloidGO:00432791320.018
negative regulation of protein modification processGO:0031400520.018
negative regulation of neurogenesisGO:0050768780.018
regulation of apoptotic processGO:00429813350.018
Human Mouse
reactive oxygen species biosynthetic processGO:190340980.018
response to acid chemicalGO:00011012220.018
nucleoside triphosphate catabolic processGO:00091431230.018
positive regulation of cellular component biogenesisGO:0044089550.018
peptide hormone secretionGO:0030072840.018
regulation of histone deacetylationGO:003106310.018
positive regulation of t cell mediated immunityGO:000271140.017
positive regulation of apoptotic processGO:00430651540.017
positive regulation of programmed cell deathGO:00430681570.017
response to monosaccharideGO:00342841590.017
negative regulation of viral processGO:004852540.017
signal releaseGO:00230611450.017
positive regulation of rna metabolic processGO:00512542030.016
actin filament bundle organizationGO:0061572190.016
amine metabolic processGO:0009308380.016
triglyceride homeostasisGO:007032820.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
negative regulation of innate immune responseGO:004582440.016
purine nucleotide metabolic processGO:00061632290.016
response to nutrient levelsGO:00316673700.016
positive regulation of immune responseGO:0050778420.016
Mouse
alcohol metabolic processGO:0006066770.016
positive regulation of phosphate metabolic processGO:00459372620.015
positive regulation of cell deathGO:00109421840.015
metal ion homeostasisGO:00550651860.015
transcription from rna polymerase ii promoterGO:00063662520.015
cellular response to alkaloidGO:0071312250.015
regulation of body fluid levelsGO:0050878900.015
positive regulation of phosphorus metabolic processGO:00105622620.015
reactive nitrogen species metabolic processGO:200105710.015
positive regulation of isotype switchingGO:004583010.015
single organism biosynthetic processGO:00447113420.015
Human
cellular response to abiotic stimulusGO:0071214850.015
positive regulation of gene expressionGO:00106282440.014
regulation of cellular localizationGO:00603412630.014
bone developmentGO:0060348250.014
protein phosphorylationGO:00064683450.014
phagocytosis recognitionGO:000691010.014
negative regulation of nervous system developmentGO:0051961790.014
response to growth factorGO:00708481890.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
negative regulation of phosphorus metabolic processGO:0010563800.014
carbohydrate derivative catabolic processGO:19011361470.014
regulation of immune responseGO:0050776550.014
Mouse
negative regulation of rna metabolic processGO:00512531230.014
positive regulation of response to stimulusGO:00485842850.014
oxidation reduction processGO:00551143040.013
developmental process involved in reproductionGO:00030061590.013
lipid biosynthetic processGO:00086101280.013
Human
multicellular organismal reproductive processGO:00486092330.013
single organism organelle organizationGO:19025891800.013
response to bacteriumGO:00096172000.013
negative regulation of gene expressionGO:00106291990.013
response to radiationGO:00093141370.013
response to vitaminGO:00332731310.013
cellular response to ketoneGO:1901655510.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
vesicle mediated transportGO:00161921810.013
divalent inorganic cation homeostasisGO:00725071650.013
cellular ion homeostasisGO:00068731840.012
lymphocyte differentiationGO:0030098100.012
Mouse
negative regulation of cell activationGO:0050866150.012
Mouse
leukocyte mediated cytotoxicityGO:0001909100.012
regulation of cell developmentGO:00602842630.012
response to reactive oxygen speciesGO:00003021200.012
reactive oxygen species metabolic processGO:0072593370.012
macromolecule catabolic processGO:0009057580.012
nucleoside phosphate metabolic processGO:00067532830.012
positive regulation of developmental processGO:00510942830.012
Mouse
somatic diversification of immunoglobulins involved in immune responseGO:000220810.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
skeletal system developmentGO:0001501410.012
gtp catabolic processGO:0006184710.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
positive regulation of cell motilityGO:2000147970.012
Mouse
regulation of phosphorus metabolic processGO:00511743490.012
membrane organizationGO:0061024940.011
amide transportGO:00428861050.011
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.011
cellular lipid metabolic processGO:00442552080.011
Human
regulation of t cell differentiation in thymusGO:003308110.011
sequestering of metal ionGO:005123890.011
positive regulation of signal transductionGO:00099671750.011
organic acid metabolic processGO:00060822920.011
Human
regulation of neuron projection developmentGO:00109751610.011
negative regulation of signal transductionGO:0009968830.011
Human Mouse
adaptive immune responseGO:0002250140.011
Mouse
defense response to gram negative bacteriumGO:005082930.011
regulation of cellular component organizationGO:00511283680.011
circulatory system developmentGO:00723591340.011
rna biosynthetic processGO:00327743800.011
metal ion transportGO:00300012890.011
positive regulation of protein metabolic processGO:00512471780.011
positive regulation of cellular component organizationGO:00511302000.011
regulation of arp2 3 complex mediated actin nucleationGO:003431520.011
agingGO:00075682410.010
regulation of cell morphogenesisGO:0022604770.010
positive regulation of cellular amine metabolic processGO:003324030.010
nucleic acid templated transcriptionGO:00976593790.010
spindle organizationGO:000705120.010
actin polymerization or depolymerizationGO:0008154140.010
establishment of organelle localizationGO:0051656370.010
muscle structure developmentGO:0061061870.010
localization of cellGO:00516742020.010
Mouse
cell part morphogenesisGO:00329901230.010
nucleobase containing small molecule metabolic processGO:00550863160.010
regulation of multicellular organismal developmentGO:20000263760.010
Mouse
regulation of cytoskeleton organizationGO:0051493490.010
embryonic pattern specificationGO:000988010.010
regulation of intracellular transportGO:0032386650.010
chaperone mediated protein foldingGO:006107760.010
Mouse

Cd74 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011