IMP: Integrative Multi-species Prediction

Rattus norvegicus

98 known processes

Tgfbr3

transforming growth factor, beta receptor III

(Aliases: betaglycan)

Entrez: 29610
Ensembl: ENSRNOG00000002093
RGD: 61821
UniProtKB: P26342

Process Predictions
Disease Predictions

Tgfbr3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of cell motility	GO:2000147	97	0.626
female gonad development	GO:0008585	53	0.435
regulation of phosphorus metabolic process	GO:0051174	349	0.404
cell migration	GO:0016477	197	0.395	Mouse
response to external biotic stimulus	GO:0043207	221	0.382
tissue development	GO:0009888	252	0.370	Human Mouse
positive regulation of developmental process	GO:0051094	283	0.362
response to cytokine	GO:0034097	215	0.352
transcription from rna polymerase ii promoter	GO:0006366	252	0.350	Human
tissue remodeling	GO:0048771	40	0.336
cellular response to oxygen containing compound	GO:1901701	386	0.333
regulation of cell motility	GO:2000145	131	0.325	Mouse
regulation of molecular function	GO:0065009	398	0.299
nucleic acid templated transcription	GO:0097659	379	0.294	Human Mouse
cell motility	GO:0048870	202	0.278	Mouse
regulation of nucleic acid templated transcription	GO:1903506	380	0.266	Human Mouse
epithelium development	GO:0060429	96	0.265
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.264
gonad development	GO:0008406	104	0.258
positive regulation of cellular component movement	GO:0051272	102	0.258
gland development	GO:0048732	155	0.256	Mouse
localization of cell	GO:0051674	202	0.247	Mouse
cellular response to glucocorticoid stimulus	GO:0071385	68	0.245
rna metabolic process	GO:0016070	406	0.245	Human Mouse
regulation of cell development	GO:0060284	263	0.241	Mouse
locomotion	GO:0040011	237	0.239	Mouse
reproductive process	GO:0022414	372	0.232
response to insulin	GO:0032868	133	0.231
positive regulation of biosynthetic process	GO:0009891	319	0.227
positive regulation of cell differentiation	GO:0045597	217	0.223
developmental process involved in reproduction	GO:0003006	159	0.215
cell differentiation involved in kidney development	GO:0061005	4	0.213
regulation of phosphorylation	GO:0042325	248	0.213
cell matrix adhesion	GO:0007160	19	0.212
macromolecular complex subunit organization	GO:0043933	339	0.212
protein complex assembly	GO:0006461	263	0.211
cellular response to growth factor stimulus	GO:0071363	162	0.210
aging	GO:0007568	241	0.210
response to nutrient levels	GO:0031667	370	0.210
cytokine mediated signaling pathway	GO:0019221	43	0.208
response to other organism	GO:0051707	220	0.207
neuron development	GO:0048666	286	0.205
leukocyte differentiation	GO:0002521	30	0.202
positive regulation of mapk cascade	GO:0043410	92	0.199
cellular component morphogenesis	GO:0032989	155	0.195	Human Mouse
protein complex subunit organization	GO:0071822	302	0.195
response to growth factor	GO:0070848	189	0.194
response to hypoxia	GO:0001666	231	0.192
positive regulation of multicellular organismal process	GO:0051240	387	0.192
regulation of anatomical structure morphogenesis	GO:0022603	141	0.190	Mouse
regulation of intracellular signal transduction	GO:1902531	218	0.182
regulation of transcription dna templated	GO:0006355	374	0.182	Human Mouse
tissue morphogenesis	GO:0048729	22	0.176	Mouse
response to decreased oxygen levels	GO:0036293	237	0.174
multicellular organism reproduction	GO:0032504	233	0.173
cell activation	GO:0001775	97	0.173
response to glucocorticoid	GO:0051384	223	0.169
kidney development	GO:0001822	67	0.168
regulation of phosphate metabolic process	GO:0019220	349	0.165
cellular response to endogenous stimulus	GO:0071495	377	0.164
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.159
sex differentiation	GO:0007548	113	0.157
regulation of catalytic activity	GO:0050790	304	0.156
development of primary female sexual characteristics	GO:0046545	56	0.155
rna biosynthetic process	GO:0032774	380	0.154	Human Mouse
oxoacid metabolic process	GO:0043436	290	0.154
female sex differentiation	GO:0046660	59	0.153
response to reactive oxygen species	GO:0000302	120	0.153
positive regulation of cell development	GO:0010720	176	0.152
regulation of apoptotic process	GO:0042981	335	0.149
negative regulation of cellular metabolic process	GO:0031324	281	0.148
mapk cascade	GO:0000165	140	0.145
cellular modified amino acid metabolic process	GO:0006575	61	0.145
signal transduction by phosphorylation	GO:0023014	144	0.145
regulation of smooth muscle cell proliferation	GO:0048660	75	0.144
response to inorganic substance	GO:0010035	377	0.144
secretion	GO:0046903	307	0.143
positive regulation of locomotion	GO:0040017	102	0.142
muscle structure development	GO:0061061	87	0.141	Mouse
anatomical structure morphogenesis	GO:0009653	298	0.139	Human Mouse
regulation of rna metabolic process	GO:0051252	391	0.136	Human Mouse
intracellular signal transduction	GO:0035556	314	0.136	Human
negative regulation of cell death	GO:0060548	229	0.130
regulation of multicellular organismal development	GO:2000026	376	0.128	Mouse
reproductive structure development	GO:0048608	128	0.128
regulation of ion transport	GO:0043269	245	0.128
carboxylic acid metabolic process	GO:0019752	289	0.127
positive regulation of cellular biosynthetic process	GO:0031328	295	0.126
leukocyte homeostasis	GO:0001776	7	0.123
negative regulation of programmed cell death	GO:0043069	183	0.123
positive regulation of phosphorus metabolic process	GO:0010562	262	0.122
positive regulation of cell migration	GO:0030335	96	0.120
regulation of mapk cascade	GO:0043408	116	0.120
homeostatic process	GO:0042592	331	0.118	Mouse
erk1 and erk2 cascade	GO:0070371	48	0.118
apoptotic process	GO:0006915	381	0.117
transcription dna templated	GO:0006351	377	0.117	Human Mouse
positive regulation of cell proliferation	GO:0008284	249	0.117
epithelial cell differentiation	GO:0030855	71	0.117
neuron differentiation	GO:0030182	368	0.114
macromolecular complex assembly	GO:0065003	273	0.113
response to oxidative stress	GO:0006979	186	0.113
metanephric tubule development	GO:0072170	4	0.112
negative regulation of apoptotic process	GO:0043066	181	0.112
regulation of cellular component movement	GO:0051270	150	0.112	Human Mouse
cardiovascular system development	GO:0072358	134	0.112	Human Mouse
cellular response to cytokine stimulus	GO:0071345	127	0.111
programmed cell death	GO:0012501	392	0.111
development of primary sexual characteristics	GO:0045137	107	0.111
circulatory system development	GO:0072359	134	0.111	Human Mouse
epithelial cell differentiation involved in kidney development	GO:0035850	3	0.111
regulation of cell morphogenesis	GO:0022604	77	0.110	Mouse
cell type specific apoptotic process	GO:0097285	134	0.108
cellular response to peptide hormone stimulus	GO:0071375	120	0.107
cellular component biogenesis	GO:0044085	368	0.107
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.107	Human
response to peptide	GO:1901652	292	0.106
cytoskeleton organization	GO:0007010	111	0.106
regulation of programmed cell death	GO:0043067	341	0.106
positive regulation of cell communication	GO:0010647	271	0.104
positive regulation of phosphate metabolic process	GO:0045937	262	0.103
muscle cell proliferation	GO:0033002	84	0.103	Mouse
protein oligomerization	GO:0051259	191	0.099
cation transport	GO:0006812	382	0.098
regulation of cellular ketone metabolic process	GO:0010565	27	0.095
response to heat	GO:0009408	60	0.095
leukocyte activation involved in immune response	GO:0002366	16	0.094
negative regulation of transport	GO:0051051	136	0.093
regulation of cell migration	GO:0030334	128	0.093	Mouse
action potential	GO:0001508	54	0.093
single organism intracellular transport	GO:1902582	166	0.093
brain development	GO:0007420	247	0.093
cellular response to peptide	GO:1901653	133	0.092
negative regulation of gene expression	GO:0010629	199	0.091
regulation of protein modification process	GO:0031399	194	0.091
blood vessel development	GO:0001568	69	0.091	Mouse
myeloid cell differentiation	GO:0030099	22	0.091	Mouse
regeneration	GO:0031099	163	0.090
male sex differentiation	GO:0046661	64	0.089
central nervous system development	GO:0007417	311	0.089
organic acid metabolic process	GO:0006082	292	0.087
regulation of sodium ion transmembrane transporter activity	GO:2000649	4	0.086
positive regulation of rna biosynthetic process	GO:1902680	197	0.085
regulated secretory pathway	GO:0045055	17	0.084
cell cell signaling	GO:0007267	335	0.084
renal system development	GO:0072001	67	0.084
t cell activation	GO:0042110	29	0.083
response to monosaccharide	GO:0034284	159	0.083
cellular component movement	GO:0006928	248	0.083	Human Mouse
immune system development	GO:0002520	41	0.082	Mouse
negative regulation of amine transport	GO:0051953	24	0.082
regulation of response to wounding	GO:1903034	69	0.081
regulation of secretion	GO:0051046	224	0.080
vesicle mediated transport	GO:0016192	181	0.080
multi organism reproductive process	GO:0044703	262	0.080
negative regulation of signal transduction	GO:0009968	83	0.079
protein complex biogenesis	GO:0070271	263	0.079
immune response	GO:0006955	104	0.079	Human
reproductive system development	GO:0061458	128	0.079
g protein coupled purinergic receptor signaling pathway	GO:0035588	8	0.078
positive regulation of signaling	GO:0023056	270	0.078
single organism reproductive process	GO:0044702	297	0.078
regulation of synaptic plasticity	GO:0048167	70	0.078
response to radiation	GO:0009314	137	0.078
biological adhesion	GO:0022610	110	0.078
response to wounding	GO:0009611	254	0.077
positive regulation of neurogenesis	GO:0050769	165	0.077
response to carbohydrate	GO:0009743	183	0.077
intracellular transport	GO:0046907	185	0.077
negative regulation of metabolic process	GO:0009892	331	0.076
adenosine receptor signaling pathway	GO:0001973	7	0.076
response to hydrogen peroxide	GO:0042542	89	0.076
cellular response to hormone stimulus	GO:0032870	247	0.075
calcium ion homeostasis	GO:0055074	162	0.075
leukocyte activation	GO:0045321	76	0.075
cellular response to corticosteroid stimulus	GO:0071384	69	0.075
ovulation cycle process	GO:0022602	50	0.073
single organism catabolic process	GO:0044712	283	0.073
signal release	GO:0023061	145	0.072
head development	GO:0060322	247	0.072
regulation of transforming growth factor beta3 production	GO:0032910	2	0.070
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:0097296	1	0.070
response to estradiol	GO:0032355	164	0.069
regulation of rna biosynthetic process	GO:2001141	381	0.069	Human Mouse
heart contraction	GO:0060047	57	0.069
positive regulation of leukocyte activation	GO:0002696	30	0.068
response to biotic stimulus	GO:0009607	226	0.068
nucleoside triphosphate metabolic process	GO:0009141	144	0.068
regulation of homeostatic process	GO:0032844	101	0.067
cellular response to molecule of bacterial origin	GO:0071219	56	0.067
ion homeostasis	GO:0050801	212	0.067
kidney mesenchyme development	GO:0072074	2	0.066
protein heterooligomerization	GO:0051291	89	0.066
negative regulation of cell proliferation	GO:0008285	119	0.066	Mouse
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.066
myeloid leukocyte differentiation	GO:0002573	20	0.065
positive regulation of focal adhesion assembly	GO:0051894	2	0.065
regulation of organ formation	GO:0003156	2	0.065
defense response	GO:0006952	194	0.064
positive regulation of transcription dna templated	GO:0045893	197	0.063
secretion by cell	GO:0032940	248	0.062
immune system process	GO:0002376	204	0.062	Human Mouse
cellular metal ion homeostasis	GO:0006875	172	0.062
synaptic transmission	GO:0007268	235	0.062
endothelial cell differentiation	GO:0045446	9	0.062
response to temperature stimulus	GO:0009266	94	0.062
muscle system process	GO:0003012	115	0.062
regulation of cellular localization	GO:0060341	263	0.062
regulation of epithelial cell differentiation	GO:0030856	12	0.061
multicellular organismal reproductive process	GO:0048609	233	0.061
tube morphogenesis	GO:0035239	23	0.061
regulation of membrane potential	GO:0042391	110	0.061
glomerulus morphogenesis	GO:0072102	1	0.060
response to hexose	GO:0009746	144	0.060
homeostasis of number of cells	GO:0048872	10	0.059	Mouse
response to mechanical stimulus	GO:0009612	134	0.059
actin cytoskeleton organization	GO:0030036	73	0.059
regulation of cellular amino acid metabolic process	GO:0006521	2	0.057
response to glucose	GO:0009749	136	0.057
mast cell degranulation	GO:0043303	10	0.057
hemopoiesis	GO:0030097	34	0.057	Mouse
sensory perception	GO:0007600	101	0.056
response to peptide hormone	GO:0043434	278	0.056
regulation of leukocyte activation	GO:0002694	45	0.056
lipid metabolic process	GO:0006629	283	0.056
regulation of metanephros development	GO:0072215	4	0.056
response to corticosteroid	GO:0031960	235	0.056
organelle organization	GO:0006996	266	0.055
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.055	Mouse
positive regulation of neuron projection development	GO:0010976	99	0.055
response to toxic substance	GO:0009636	133	0.055
cellular response to lipid	GO:0071396	201	0.055
positive regulation of leukocyte degranulation	GO:0043302	4	0.055
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.054
regulation of protein phosphorylation	GO:0001932	183	0.054
hormone metabolic process	GO:0042445	69	0.054
purine containing compound metabolic process	GO:0072521	253	0.053
liver development	GO:0001889	90	0.053	Mouse
cellular response to lipopolysaccharide	GO:0071222	55	0.052
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.052
blood vessel morphogenesis	GO:0048514	58	0.052
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.052
positive regulation of immune system process	GO:0002684	90	0.051
response to metal ion	GO:0010038	253	0.051
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.051
defecation	GO:0030421	1	0.051
gliogenesis	GO:0042063	93	0.051
smooth muscle cell migration	GO:0014909	36	0.051
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.050
cellular response to organonitrogen compound	GO:0071417	197	0.050
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.050
positive regulation of leukocyte migration	GO:0002687	21	0.050
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.050
negative regulation of multicellular organismal process	GO:0051241	203	0.049	Mouse
regulation of response to external stimulus	GO:0032101	106	0.049
regulation of protein metabolic process	GO:0051246	289	0.049
negative regulation of phosphate metabolic process	GO:0045936	80	0.049
regulation of nervous system development	GO:0051960	264	0.049
cellular response to insulin stimulus	GO:0032869	81	0.049
chemical homeostasis	GO:0048878	292	0.048
regulation of neutrophil apoptotic process	GO:0033029	4	0.048
cation homeostasis	GO:0055080	195	0.048
regulation of hormone levels	GO:0010817	187	0.048
organic hydroxy compound biosynthetic process	GO:1901617	51	0.048
regulation of cell differentiation	GO:0045595	320	0.047	Mouse
circulatory system process	GO:0003013	183	0.047
positive regulation of cellular component organization	GO:0051130	200	0.047
positive regulation of retinal cell programmed cell death	GO:0046670	1	0.046
peptidyl amino acid modification	GO:0018193	126	0.046
positive regulation of rna metabolic process	GO:0051254	203	0.046
peptidyl tyrosine phosphorylation	GO:0018108	72	0.046
reactive oxygen species metabolic process	GO:0072593	37	0.045
cellular response to nitrogen compound	GO:1901699	210	0.045
smooth muscle cell proliferation	GO:0048659	77	0.045
cellular protein localization	GO:0034613	122	0.045
positive regulation of transforming growth factor beta3 production	GO:0032916	2	0.045
positive regulation of gene expression	GO:0010628	244	0.045
positive regulation of mast cell activation	GO:0033005	4	0.045
macromolecule localization	GO:0033036	252	0.045
positive regulation of neuron differentiation	GO:0045666	126	0.044
carbohydrate metabolic process	GO:0005975	130	0.044
nucleotide catabolic process	GO:0009166	139	0.044
response to camp	GO:0051591	91	0.044
lymphocyte activation	GO:0046649	43	0.044
urogenital system development	GO:0001655	78	0.044
coronary vasculature morphogenesis	GO:0060977	3	0.044
signal transduction involved in regulation of gene expression	GO:0023019	4	0.044
angiogenesis	GO:0001525	53	0.044
blood circulation	GO:0008015	183	0.044
organ formation	GO:0048645	3	0.043
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.043
g protein coupled receptor signaling pathway	GO:0007186	242	0.043
positive regulation of catalytic activity	GO:0043085	184	0.043
response to molecule of bacterial origin	GO:0002237	194	0.043
neuron projection development	GO:0031175	273	0.043
taxis	GO:0042330	67	0.043
positive regulation of response to stimulus	GO:0048584	285	0.043
negative regulation of response to stimulus	GO:0048585	155	0.042
cellular amino acid metabolic process	GO:0006520	107	0.042
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.042
regulation of neurogenesis	GO:0050767	247	0.042
positive regulation of phosphorylation	GO:0042327	177	0.041
response to nutrient	GO:0007584	248	0.041
regulation of neuron apoptotic process	GO:0043523	83	0.041
positive regulation of intracellular signal transduction	GO:1902533	138	0.041
kidney epithelium development	GO:0072073	19	0.041
positive regulation of nervous system development	GO:0051962	178	0.041
positive regulation of protein metabolic process	GO:0051247	178	0.041
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.041	Mouse
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.041
negative regulation of phosphorus metabolic process	GO:0010563	80	0.040
cell adhesion	GO:0007155	110	0.040
negative regulation of rna metabolic process	GO:0051253	123	0.040
positive regulation of protein phosphorylation	GO:0001934	135	0.040
protein phosphorylation	GO:0006468	345	0.040
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.039
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	10	0.039
lymphoid progenitor cell differentiation	GO:0002320	2	0.039
positive regulation of cell death	GO:0010942	184	0.038
alpha beta t cell differentiation	GO:0046632	2	0.038
response to oxygen levels	GO:0070482	265	0.038
monovalent inorganic cation transport	GO:0015672	172	0.037
male gonad development	GO:0008584	59	0.037
regulation of immune system process	GO:0002682	123	0.037
regulation of cell proliferation	GO:0042127	359	0.037	Mouse
hormone secretion	GO:0046879	115	0.036
mast cell mediated immunity	GO:0002448	10	0.036
regulation of cellular amine metabolic process	GO:0033238	8	0.036
positive regulation of cell projection organization	GO:0031346	111	0.036
negative regulation of protein phosphorylation	GO:0001933	44	0.036
sensory perception of pain	GO:0019233	73	0.036
regulation of cellular protein metabolic process	GO:0032268	267	0.036
response to ionizing radiation	GO:0010212	59	0.036
ras protein signal transduction	GO:0007265	29	0.036
carbohydrate derivative metabolic process	GO:1901135	346	0.035
rhythmic process	GO:0048511	156	0.035
negative regulation of secretion by cell	GO:1903531	72	0.035
monosaccharide metabolic process	GO:0005996	61	0.035
negative regulation of macromolecule metabolic process	GO:0010605	260	0.035
heterocycle catabolic process	GO:0046700	167	0.035
regulation of defense response	GO:0031347	68	0.035
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.035
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.035
positive regulation of cellular amine metabolic process	GO:0033240	3	0.035
tube development	GO:0035295	89	0.034
cell projection organization	GO:0030030	302	0.034
monocarboxylic acid metabolic process	GO:0032787	152	0.034
regulation of erk1 and erk2 cascade	GO:0070372	41	0.034
metanephric epithelium development	GO:0072207	4	0.034
morphogenesis of an epithelium	GO:0002009	20	0.034
response to lipopolysaccharide	GO:0032496	191	0.034
response to extracellular stimulus	GO:0009991	380	0.034
cellular cation homeostasis	GO:0030003	180	0.034
cell substrate adhesion	GO:0031589	29	0.034
regulation of endothelial cell differentiation	GO:0045601	4	0.034
response to bacterium	GO:0009617	200	0.034
metanephric tubule morphogenesis	GO:0072173	2	0.033
positive regulation of molecular function	GO:0044093	230	0.033	Mouse
organ regeneration	GO:0031100	101	0.033
regulation of cellular component biogenesis	GO:0044087	86	0.033
cell part morphogenesis	GO:0032990	123	0.032
regulation of cell adhesion	GO:0030155	52	0.032
metanephric mesenchyme development	GO:0072075	2	0.032
cellular component assembly	GO:0022607	360	0.032
regulation of muscle cell apoptotic process	GO:0010660	26	0.032
cellular amine metabolic process	GO:0044106	38	0.032
regulation of epithelial cell differentiation involved in kidney development	GO:2000696	1	0.032
positive regulation of map kinase activity	GO:0043406	46	0.032
single organism organelle organization	GO:1902589	180	0.032
sequestering of calcium ion	GO:0051208	8	0.031
response to vitamin	GO:0033273	131	0.031
divalent inorganic cation transport	GO:0072511	134	0.031
negative regulation of neutrophil apoptotic process	GO:0033030	3	0.031
positive regulation of adherens junction organization	GO:1903393	2	0.031
organophosphate metabolic process	GO:0019637	370	0.031
amine metabolic process	GO:0009308	38	0.031
b cell differentiation	GO:0030183	2	0.031
growth	GO:0040007	165	0.031
positive regulation of serotonin secretion	GO:0014064	1	0.031
sulfur compound metabolic process	GO:0006790	70	0.031
negative regulation of biosynthetic process	GO:0009890	168	0.031
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.031
regulation of system process	GO:0044057	208	0.030
aromatic compound catabolic process	GO:0019439	168	0.030
vasculogenesis	GO:0001570	3	0.030
ensheathment of neurons	GO:0007272	40	0.030
myeloid leukocyte mediated immunity	GO:0002444	12	0.030
mesenchymal cell proliferation	GO:0010463	4	0.030
catabolic process	GO:0009056	351	0.030
regulation of mesenchymal cell proliferation	GO:0010464	4	0.030
positive regulation of synaptic transmission	GO:0050806	62	0.030
endothelium development	GO:0003158	12	0.030
cell morphogenesis involved in differentiation	GO:0000904	119	0.030	Human Mouse
regulation of signal transduction	GO:0009966	318	0.030
negative regulation of calcium ion import	GO:0090281	2	0.030
cellular homeostasis	GO:0019725	252	0.030
negative regulation of metanephros development	GO:0072217	2	0.030
regulation of regulated secretory pathway	GO:1903305	7	0.029
vesicle fusion	GO:0006906	14	0.029
proteolysis	GO:0006508	175	0.029
retinoic acid receptor signaling pathway	GO:0048384	7	0.029
heart process	GO:0003015	57	0.029
cellular chemical homeostasis	GO:0055082	247	0.029
regulation of synaptic transmission	GO:0050804	141	0.029
regulation of map kinase activity	GO:0043405	53	0.029
negative regulation of kidney development	GO:0090185	2	0.028
mononuclear cell proliferation	GO:0032943	29	0.028
regulation of vesicle mediated transport	GO:0060627	81	0.028
positive regulation of endothelial cell migration	GO:0010595	4	0.028
metal ion homeostasis	GO:0055065	186	0.028
organic hydroxy compound metabolic process	GO:1901615	115	0.028
membrane organization	GO:0061024	94	0.028
axon ensheathment	GO:0008366	40	0.028
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.028
nucleobase containing compound catabolic process	GO:0034655	152	0.027
striated muscle tissue development	GO:0014706	58	0.027	Mouse
cell junction assembly	GO:0034329	18	0.027
small molecule biosynthetic process	GO:0044283	124	0.027
negative regulation of protein metabolic process	GO:0051248	114	0.027
hematopoietic or lymphoid organ development	GO:0048534	36	0.027	Mouse
bmp signaling pathway	GO:0030509	4	0.027	Human
regulation of satellite cell proliferation	GO:0014842	1	0.027
regulation of hormone secretion	GO:0046883	106	0.027
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.027
hepaticobiliary system development	GO:0061008	90	0.027	Mouse
multi multicellular organism process	GO:0044706	138	0.027
cellular nitrogen compound catabolic process	GO:0044270	163	0.027
regulation of kinase activity	GO:0043549	117	0.026
cellular response to organic cyclic compound	GO:0071407	202	0.026
regulation of leukocyte differentiation	GO:1902105	20	0.026
inflammatory cell apoptotic process	GO:0006925	5	0.026
metal ion transport	GO:0030001	289	0.026
regulation of lipid metabolic process	GO:0019216	68	0.026
glycerolipid metabolic process	GO:0046486	67	0.026
myeloid cell activation involved in immune response	GO:0002275	13	0.026
negative regulation of intracellular signal transduction	GO:1902532	38	0.026
axon development	GO:0061564	96	0.026
negative regulation of secretion	GO:0051048	82	0.025
embryo development	GO:0009790	49	0.025	Mouse
ribose phosphate metabolic process	GO:0019693	235	0.025
mast cell chemotaxis	GO:0002551	4	0.025
regulation of neuron death	GO:1901214	115	0.025
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	41	0.025
carbohydrate homeostasis	GO:0033500	75	0.025
acylglycerol metabolic process	GO:0006639	21	0.025
exocytosis	GO:0006887	60	0.025
nucleoside phosphate metabolic process	GO:0006753	283	0.025
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0003339	2	0.025
metanephric mesenchymal cell differentiation	GO:0072162	1	0.025
neurological system process	GO:0050877	219	0.025
intracellular protein transport	GO:0006886	79	0.025
nitrogen compound transport	GO:0071705	229	0.025
regulation of leukocyte migration	GO:0002685	24	0.025
purine nucleoside metabolic process	GO:0042278	169	0.025
nucleobase containing small molecule metabolic process	GO:0055086	316	0.025
jak stat cascade	GO:0007259	26	0.025
negative regulation of transcription dna templated	GO:0045892	116	0.024
skeletal system development	GO:0001501	41	0.024
phenol containing compound metabolic process	GO:0018958	30	0.024
transmembrane transport	GO:0055085	412	0.024
single organism carbohydrate metabolic process	GO:0044723	118	0.024
response to ethanol	GO:0045471	162	0.024
neutrophil apoptotic process	GO:0001781	4	0.024
negative regulation of signaling	GO:0023057	157	0.024
response to alkaloid	GO:0043279	132	0.024
protein autophosphorylation	GO:0046777	66	0.024
angioblast cell migration	GO:0035476	1	0.024
melanocyte differentiation	GO:0030318	2	0.024
angiogenesis involved in coronary vascular morphogenesis	GO:0060978	3	0.024
vasculature development	GO:0001944	70	0.023	Mouse
cellular response to transforming growth factor beta stimulus	GO:0071560	41	0.023
wound healing	GO:0042060	122	0.023
neutral lipid metabolic process	GO:0006638	21	0.023
negative regulation of cell communication	GO:0010648	158	0.023
cellular response to oxidative stress	GO:0034599	76	0.023
cellular ketone metabolic process	GO:0042180	51	0.023
single organism behavior	GO:0044708	130	0.023
organic cyclic compound catabolic process	GO:1901361	175	0.023
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	GO:1902728	1	0.023
locomotory exploration behavior	GO:0035641	1	0.023
response to purine containing compound	GO:0014074	126	0.023
cell cell junction organization	GO:0045216	20	0.023
leukocyte mediated immunity	GO:0002443	28	0.023
positive regulation of programmed cell death	GO:0043068	157	0.023
defense response to other organism	GO:0098542	17	0.023
regulation of locomotion	GO:0040012	148	0.023	Mouse
positive regulation of secretion by cell	GO:1903532	128	0.022

Tgfbr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.053
disease of cellular proliferation	DOID:14566	0.053
nervous system disease	DOID:863	0.044
disease of anatomical entity	DOID:7	0.044
central nervous system disease	DOID:331	0.038
disease of metabolism	DOID:0014667	0.034
organ system cancer	DOID:0050686	0.032

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