Rattus norvegicus

22 known processes

Tac2

tachykinin 2

(Aliases: Tac3)

Tac2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component organizationGO:00511283680.237
synaptic transmissionGO:00072682350.218
muscle contractionGO:0006936880.198
single organism biosynthetic processGO:00447113420.192
response to glucocorticoidGO:00513842230.188
positive regulation of synaptic transmissionGO:0050806620.164
cellular component biogenesisGO:00440853680.158
regulation of intracellular signal transductionGO:19025312180.156
response to corticosteroidGO:00319602350.154
cellular component assemblyGO:00226073600.154
response to woundingGO:00096112540.154
muscle system processGO:00030121150.140
regulation of cell proliferationGO:00421273590.139
response to estrogenGO:00436272320.135
metal ion transportGO:00300012890.135
g protein coupled receptor signaling pathwayGO:00071862420.126
oxoacid metabolic processGO:00434362900.124
protein complex biogenesisGO:00702712630.104
neurological system processGO:00508772190.099
response to ketoneGO:19016541820.098
ion homeostasisGO:00508012120.098
negative regulation of metabolic processGO:00098923310.096
cellular amino acid metabolic processGO:00065201070.094
regulation of signal transductionGO:00099663180.091
positive regulation of response to stimulusGO:00485842850.090
cellular component movementGO:00069282480.089
response to inorganic substanceGO:00100353770.088
head developmentGO:00603222470.087
positive regulation of signalingGO:00230562700.086
cell cell signalingGO:00072673350.086
regulation of membrane potentialGO:00423911100.085
response to oxygen levelsGO:00704822650.083
regulation of blood circulationGO:19035221100.082
positive regulation of cytosolic calcium ion concentrationGO:00072041220.081
protein complex assemblyGO:00064612630.081
regulation of protein metabolic processGO:00512462890.080
macromolecular complex subunit organizationGO:00439333390.078
neuron projection morphogenesisGO:00488121220.077
negative regulation of cellular metabolic processGO:00313242810.076
macromolecular complex assemblyGO:00650032730.076
tissue developmentGO:00098882520.076
regulation of molecular functionGO:00650093980.076
neuron differentiationGO:00301823680.075
inflammatory responseGO:00069541500.072
positive regulation of cell communicationGO:00106472710.072
cellular response to corticosteroid stimulusGO:0071384690.071
regulation of multicellular organismal developmentGO:20000263760.070
positive regulation of secretion by cellGO:19035321280.068
organophosphate biosynthetic processGO:00904071430.067
negative regulation of growthGO:0045926370.066
cation transmembrane transportGO:00986552630.064
protein oligomerizationGO:00512591910.064
regulation of phosphorus metabolic processGO:00511743490.063
single organism reproductive processGO:00447022970.062
cellular ion homeostasisGO:00068731840.061
protein phosphorylationGO:00064683450.061
sensory perception of painGO:0019233730.060
organic anion transportGO:00157111320.060
transcription dna templatedGO:00063513770.060
wound healingGO:00420601220.060
multi organism reproductive processGO:00447032620.059
cellular response to alcoholGO:0097306870.059
circulatory system developmentGO:00723591340.058
cellular response to growth factor stimulusGO:00713631620.058
cation homeostasisGO:00550801950.057
positive regulation of developmental processGO:00510942830.057
rhythmic processGO:00485111560.057
regulation of secretionGO:00510462240.057
positive regulation of transportGO:00510502450.056
regulation of nucleic acid templated transcriptionGO:19035063800.056
organic acid metabolic processGO:00060822920.056
protein complex subunit organizationGO:00718223020.055
localization of cellGO:00516742020.055
carboxylic acid metabolic processGO:00197522890.054
regulation of cellular amine metabolic processGO:003323880.053
sensory perceptionGO:00076001010.053
positive regulation of phosphorus metabolic processGO:00105622620.053
cell morphogenesisGO:00009021420.053
cellular response to endogenous stimulusGO:00714953770.052
regulation of protein phosphorylationGO:00019321830.052
positive regulation of macromolecule biosynthetic processGO:00105572470.052
cellular response to hormone stimulusGO:00328702470.051
response to nutrient levelsGO:00316673700.051
neuron projection developmentGO:00311752730.051
regulation of cell differentiationGO:00455953200.051
regulation of phosphate metabolic processGO:00192203490.051
negative regulation of multicellular organismal processGO:00512412030.050
response to extracellular stimulusGO:00099913800.050
cell morphogenesis involved in neuron differentiationGO:00486671060.050
developmental growthGO:00485891000.050
transmembrane transportGO:00550854120.049
cell projection organizationGO:00300303020.049
neuron developmentGO:00486662860.049
cyclic nucleotide biosynthetic processGO:0009190630.049
growthGO:00400071650.049
regulation of system processGO:00440572080.048
secretion by cellGO:00329402480.048
blood circulationGO:00080151830.048
chemical homeostasisGO:00488782920.048
regulation of synaptic transmissionGO:00508041410.047
response to growth factorGO:00708481890.047
cell morphogenesis involved in differentiationGO:00009041190.046
anatomical structure morphogenesisGO:00096532980.046
cellular response to lipidGO:00713962010.046
nucleic acid templated transcriptionGO:00976593790.045
cellular response to organonitrogen compoundGO:00714171970.045
regulation of blood vessel sizeGO:0050880890.045
homeostatic processGO:00425923310.045
organonitrogen compound biosynthetic processGO:19015661670.044
negative regulation of response to stimulusGO:00485851550.044
transmission of nerve impulseGO:0019226420.043
regulation of cellular ketone metabolic processGO:0010565270.043
rna metabolic processGO:00160704060.043
secretionGO:00469033070.042
regulation of cell developmentGO:00602842630.042
positive regulation of cellular component organizationGO:00511302000.042
regulation of cell projection organizationGO:00313441750.042
multicellular organismal reproductive processGO:00486092330.042
regulation of blood pressureGO:0008217830.041
regulation of transcription from rna polymerase ii promoterGO:00063572340.041
cell part morphogenesisGO:00329901230.041
regulation of muscle system processGO:0090257790.040
positive regulation of nucleobase containing compound metabolic processGO:00459353190.040
programmed cell deathGO:00125013920.040
circulatory system processGO:00030131830.040
positive regulation of intracellular signal transductionGO:19025331380.040
reproductive processGO:00224143720.039
positive regulation of nitrogen compound metabolic processGO:00511733340.039
brain developmentGO:00074202470.039
negative regulation of phosphate metabolic processGO:0045936800.038
positive regulation of molecular functionGO:00440932300.038
action potentialGO:0001508540.038
rna biosynthetic processGO:00327743800.038
positive regulation of signal transductionGO:00099671750.038
cellular response to organic cyclic compoundGO:00714072020.037
response to hypoxiaGO:00016662310.037
regulation of transcription dna templatedGO:00063553740.037
negative regulation of cell proliferationGO:00082851190.036
positive regulation of nervous system developmentGO:00519621780.036
response to mechanical stimulusGO:00096121340.036
organic substance catabolic processGO:19015753160.036
heart morphogenesisGO:000300730.036
central nervous system developmentGO:00074173110.035
regulation of cellular amino acid metabolic processGO:000652120.035
cytosolic calcium ion homeostasisGO:00514801400.035
agingGO:00075682410.035
defense responseGO:00069521940.035
positive regulation of cell proliferationGO:00082842490.035
regulation of response to stressGO:00801341260.034
negative regulation of macromolecule metabolic processGO:00106052600.034
amine metabolic processGO:0009308380.033
organelle organizationGO:00069962660.033
nucleotide biosynthetic processGO:0009165980.033
nucleoside phosphate metabolic processGO:00067532830.033
vascular process in circulatory systemGO:0003018960.033
biological adhesionGO:00226101100.033
ribose phosphate metabolic processGO:00196932350.033
cellular response to oxygen containing compoundGO:19017013860.033
single organism behaviorGO:00447081300.033
limb morphogenesisGO:003510840.033
positive regulation of protein phosphorylationGO:00019341350.033
purine containing compound metabolic processGO:00725212530.032
regulation of kinase activityGO:00435491170.032
positive regulation of cellular protein metabolic processGO:00322701670.032
regulation of ion transportGO:00432692450.031
forebrain developmentGO:0030900980.031
positive regulation of cell differentiationGO:00455972170.031
response to nutrientGO:00075842480.031
reproductionGO:00000032450.031
regulation of rna metabolic processGO:00512523910.031
cellular divalent inorganic cation homeostasisGO:00725031620.031
metal ion homeostasisGO:00550651860.030
neuromuscular synaptic transmissionGO:000727420.030
regulation of catalytic activityGO:00507903040.030
protein homooligomerizationGO:0051260910.030
behaviorGO:00076102050.030
anterior posterior pattern specificationGO:000995210.030
regulation of protein kinase activityGO:00458591050.030
nucleobase containing small molecule metabolic processGO:00550863160.029
regulation of rna biosynthetic processGO:20011413810.029
divalent inorganic cation homeostasisGO:00725071650.029
negative regulation of developmental processGO:00510931250.029
positive regulation of catalytic activityGO:00430851840.029
cellular response to nitrogen compoundGO:19016992100.029
neuronal action potentialGO:0019228350.029
catabolic processGO:00090563510.029
mapk cascadeGO:00001651400.029
response to ethanolGO:00454711620.029
regulation of neurogenesisGO:00507672470.028
regulation of organelle organizationGO:0033043800.028
cellular response to stressGO:00335542690.028
gliogenesisGO:0042063930.028
positive regulation of multicellular organismal processGO:00512403870.028
purine ribonucleotide biosynthetic processGO:0009152810.028
negative regulation of cellular biosynthetic processGO:00313271610.028
regulation of camp biosynthetic processGO:0030817380.028
cell adhesionGO:00071551100.028
regulation of phosphorylationGO:00423252480.028
neuropeptide signaling pathwayGO:0007218290.028
multicellular organismal signalingGO:0035637440.028
heart developmentGO:0007507720.028
response to acid chemicalGO:00011012220.027
regulation of apoptotic processGO:00429813350.027
cellular response to steroid hormone stimulusGO:0071383930.027
cell growthGO:00160491040.027
cellular chemical homeostasisGO:00550822470.027
positive regulation of cell deathGO:00109421840.027
positive regulation of biosynthetic processGO:00098913190.027
response to vitaminGO:00332731310.027
ribose phosphate biosynthetic processGO:0046390870.026
transcription from rna polymerase ii promoterGO:00063662520.026
cyclic nucleotide metabolic processGO:0009187800.026
negative regulation of nervous system developmentGO:0051961790.026
positive regulation of secretionGO:00510471400.026
regulation of response to external stimulusGO:00321011060.026
glial cell differentiationGO:0010001650.026
establishment of tissue polarityGO:000716420.026
camp biosynthetic processGO:0006171470.026
cellular ketone metabolic processGO:0042180510.025
smooth muscle contractionGO:0006939370.025
single organism catabolic processGO:00447122830.025
intracellular signal transductionGO:00355563140.025
positive regulation of phosphorylationGO:00423271770.025
purine nucleotide metabolic processGO:00061632290.025
response to molecule of bacterial originGO:00022371940.025
locomotionGO:00400112370.025
embryonic appendage morphogenesisGO:003511340.025
developmental process involved in reproductionGO:00030061590.025
regulation of neurological system processGO:0031644430.025
regulation of neuron differentiationGO:00456642080.025
regulation of cellular protein metabolic processGO:00322682670.024
positive regulation of programmed cell deathGO:00430681570.024
cellular amino acid biosynthetic processGO:0008652320.024
endocytosisGO:0006897840.024
positive regulation of cellular amino acid metabolic processGO:004576410.023
regulation of nucleotide biosynthetic processGO:0030808470.023
regulation of cellular localizationGO:00603412630.023
cell projection morphogenesisGO:00488581230.023
vesicle mediated transportGO:00161921810.023
negative regulation of gene expressionGO:00106291990.023
appendage morphogenesisGO:003510740.023
negative regulation of cellular protein metabolic processGO:00322691060.023
cellular metal ion homeostasisGO:00068751720.023
regulation of nucleotide metabolic processGO:00061401170.023
multicellular organism reproductionGO:00325042330.023
positive regulation of protein modification processGO:00314011420.022
proteolysisGO:00065081750.022
protein heterooligomerizationGO:0051291890.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
small molecule biosynthetic processGO:00442831240.022
single organism organelle organizationGO:19025891800.022
cellular amine metabolic processGO:0044106380.022
negative regulation of protein metabolic processGO:00512481140.022
regulation of response to woundingGO:1903034690.022
negative regulation of transcription regulatory region dna bindingGO:200067820.022
response to lipopolysaccharideGO:00324961910.022
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
carboxylic acid biosynthetic processGO:0046394830.021
cellular component morphogenesisGO:00329891550.021
cellular catabolic processGO:00442482950.021
cellular response to external stimulusGO:00714961180.021
positive regulation of apoptotic processGO:00430651540.021
epithelium developmentGO:0060429960.021
ion transmembrane transportGO:00342203650.021
myelinationGO:0042552390.021
regulation of establishment of planar polarityGO:009017520.021
regulation of muscle contractionGO:0006937530.021
activation of protein kinase activityGO:0032147470.021
regulation of transferase activityGO:00513381230.021
regulation of programmed cell deathGO:00430673410.021
positive regulation of cellular amine metabolic processGO:003324030.021
feeding behaviorGO:0007631530.021
response to decreased oxygen levelsGO:00362932370.021
nucleoside phosphate biosynthetic processGO:19012931020.021
gland developmentGO:00487321550.021
regulation of protein modification processGO:00313991940.020
regulation of circadian sleep wake cycleGO:0042749180.020
axon developmentGO:0061564960.020
cyclic purine nucleotide metabolic processGO:0052652620.020
organophosphate metabolic processGO:00196373700.020
positive regulation of neurogenesisGO:00507691650.020
muscle tissue developmentGO:0060537580.020
cellular response to fluid shear stressGO:007149840.020
apoptotic processGO:00069153810.020
purine nucleotide biosynthetic processGO:0006164830.020
calcium ion homeostasisGO:00550741620.020
positive regulation of gene expressionGO:00106282440.020
positive regulation of phosphate metabolic processGO:00459372620.020
positive regulation of transcription dna templatedGO:00458931970.020
gamete generationGO:00072761240.020
regulation of neuron projection developmentGO:00109751610.020
monovalent inorganic cation transportGO:00156721720.019
sexual reproductionGO:00199531480.019
response to alkaloidGO:00432791320.019
regulation of cyclic nucleotide biosynthetic processGO:0030802450.019
positive regulation of rna metabolic processGO:00512542030.019
cellular calcium ion homeostasisGO:00068741600.019
negative regulation of catalytic activityGO:00430861030.019
sodium ion transmembrane transportGO:0035725670.019
positive regulation of cell developmentGO:00107201760.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
response to estradiolGO:00323551640.019
regulation of cellular component biogenesisGO:0044087860.019
purine ribonucleotide metabolic processGO:00091502270.019
regulation of cyclic nucleotide metabolic processGO:0030799510.019
cellular response to glucocorticoid stimulusGO:0071385680.019
small gtpase mediated signal transductionGO:0007264360.018
regulation of tube sizeGO:0035150890.018
regulation of cell growthGO:0001558850.018
cellular homeostasisGO:00197252520.018
lipid metabolic processGO:00066292830.018
intracellular transportGO:00469071850.018
cellular cation homeostasisGO:00300031800.018
organic acid biosynthetic processGO:0016053830.018
negative regulation of cell differentiationGO:0045596990.018
organonitrogen compound catabolic processGO:19015651790.018
axonogenesisGO:0007409710.018
regulation of cellular response to stressGO:0080135490.018
single organism carbohydrate metabolic processGO:00447231180.018
ribonucleotide biosynthetic processGO:0009260850.018
striated muscle tissue developmentGO:0014706580.018
response to foodGO:0032094270.018
positive regulation of response to external stimulusGO:0032103510.018
sensory organ developmentGO:0007423740.017
response to amino acidGO:0043200750.017
embryonic pattern specificationGO:000988010.017
negative regulation of phosphorus metabolic processGO:0010563800.017
response to ammonium ionGO:0060359710.017
cardiovascular system developmentGO:00723581340.017
regulation of cell motilityGO:20001451310.017
inorganic ion transmembrane transportGO:00986602290.017
glycerolipid metabolic processGO:0046486670.017
alcohol metabolic processGO:0006066770.017
regulation of anatomical structure sizeGO:00900661350.017
positive regulation of blood circulationGO:1903524650.017
regulation of cell migrationGO:00303341280.017
cell migrationGO:00164771970.017
negative regulation of molecular functionGO:00440921330.017
carbohydrate derivative metabolic processGO:19011353460.016
axis specificationGO:000979840.016
peptidyl amino acid modificationGO:00181931260.016
cellular response to cytokine stimulusGO:00713451270.016
protein localizationGO:00081041910.016
inorganic cation transmembrane transportGO:00986622020.016
positive regulation of cellular biosynthetic processGO:00313282950.016
regulation of mapk cascadeGO:00434081160.016
nucleotide metabolic processGO:00091172790.016
neural crest cell developmentGO:001403220.016
purine containing compound biosynthetic processGO:0072522850.016
neural crest cell differentiationGO:001403320.016
regulation of anatomical structure morphogenesisGO:00226031410.016
regulation of secretion by cellGO:19035302080.016
dendrite morphogenesisGO:0048813430.016
positive regulation of rna biosynthetic processGO:19026801970.016
response to temperature stimulusGO:0009266940.016
heart processGO:0003015570.016
synaptic transmission gabaergicGO:0051932220.016
regulation of receptor activityGO:0010469290.016
synapse assemblyGO:0007416290.016
vasodilationGO:0042311440.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
signal transduction by phosphorylationGO:00230141440.015
response to cocaineGO:0042220390.015
organ morphogenesisGO:0009887750.015
negative regulation of cell communicationGO:00106481580.015
macromolecule localizationGO:00330362520.015
negative regulation of blood pressureGO:0045776290.015
positive regulation of mapk cascadeGO:0043410920.015
spermatogenesisGO:0007283990.015
striated muscle contractionGO:0006941440.015
epithelial cell proliferationGO:0050673540.015
response to oxidative stressGO:00069791860.015
axon ensheathmentGO:0008366400.015
multi multicellular organism processGO:00447061380.015
odontogenesisGO:0042476320.014
regulation of defense responseGO:0031347680.014
response to testosteroneGO:0033574550.014
cell motilityGO:00488702020.014
organic acid transportGO:00158491160.014
phasic smooth muscle contractionGO:001482130.014
liver developmentGO:0001889900.014
nucleotide catabolic processGO:00091661390.014
renal system processGO:0003014400.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
male gamete generationGO:0048232990.014
positive regulation of protein metabolic processGO:00512471780.014
response to mineralocorticoidGO:0051385490.014
female pregnancyGO:00075651220.014
positive regulation of the force of heart contraction by chemical signalGO:000309920.014
organic hydroxy compound transportGO:0015850770.014
positive regulation of saliva secretionGO:004687830.014
protein transportGO:00150311320.013
positive regulation of ion transportGO:0043270940.013
regulation of ion homeostasisGO:2000021630.013
cellular response to oxidative stressGO:0034599760.013
hindlimb morphogenesisGO:003513720.013
ras protein signal transductionGO:0007265290.013
response to dexamethasoneGO:0071548490.013
neuron neuron synaptic transmissionGO:0007270600.013
cellular protein localizationGO:00346131220.013
response to retinoic acidGO:0032526630.013
cardiac chamber developmentGO:000320510.013
muscle structure developmentGO:0061061870.013
synaptic transmission glutamatergicGO:0035249330.013
gastrulationGO:000736920.013
single fertilizationGO:000733830.013
establishment of planar polarityGO:000173610.013
negative regulation of signal transductionGO:0009968830.013
urogenital system developmentGO:0001655780.013
asymmetric stem cell divisionGO:009872220.013
regenerationGO:00310991630.013
cellular macromolecule localizationGO:00707271220.013
regulation of circadian sleep wake cycle sleepGO:0045187180.013
peptide metabolic processGO:0006518320.013
cardiac ventricle developmentGO:000323110.013
skeletal muscle tissue regenerationGO:0043403100.012
negative regulation of neurogenesisGO:0050768780.012
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.012
ribonucleotide metabolic processGO:00092592310.012
regulation of body fluid levelsGO:0050878900.012
acid secretionGO:0046717480.012
positive regulation of cell projection organizationGO:00313461110.012
circadian sleep wake cycle sleepGO:0050802210.012
stress activated protein kinase signaling cascadeGO:0031098370.012
embryonic limb morphogenesisGO:003032640.012
positive regulation of immune system processGO:0002684900.012
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.012
ensheathment of neuronsGO:0007272400.012
rho protein signal transductionGO:0007266110.012
negative regulation of signalingGO:00230571570.012
protein homotrimerizationGO:0070207150.012
regulation of hormone levelsGO:00108171870.012
regulation of growthGO:00400081050.012
epithelial cell differentiationGO:0030855710.012
skeletal muscle tissue developmentGO:0007519310.012
receptor mediated endocytosisGO:0006898420.012
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressureGO:000202510.012
positive regulation of neuron differentiationGO:00456661260.012
regulation of dna metabolic processGO:0051052600.012
non canonical wnt signaling pathwayGO:003556730.012
negative regulation of camp metabolic processGO:0030815140.012
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.012
lipid catabolic processGO:0016042460.012
intracellular protein transportGO:0006886790.012
cation transportGO:00068123820.012
response to transition metal nanoparticleGO:19902671220.012
lipid transportGO:0006869610.012
anatomical structure formation involved in morphogenesisGO:0048646830.011
negative regulation of cell developmentGO:0010721820.011
muscle organ developmentGO:0007517500.011
neurotransmitter gated ion channel clusteringGO:007257830.011
neuron deathGO:00709971270.011
synaptic transmission cholinergicGO:0007271110.011
anion transportGO:00068201780.011
monocarboxylic acid metabolic processGO:00327871520.011
endocrine processGO:0050886320.011
positive regulation of protein kinase activityGO:0045860730.011
cellular response to ketoneGO:1901655510.011
cytoskeleton organizationGO:00070101110.011
cellular response to peptideGO:19016531330.011
jak stat cascadeGO:0007259260.011
positive regulation of response to woundingGO:1903036340.011
cellular amide metabolic processGO:0043603440.011
regulation of nervous system developmentGO:00519602640.011
cellular response to estradiol stimulusGO:0071392160.011
positive regulation of long term synaptic potentiationGO:190027340.011
regulation of neuron deathGO:19012141150.011
coagulationGO:0050817280.011
stress activated mapk cascadeGO:0051403350.011
positive regulation of transferase activityGO:0051347810.011
limbic system developmentGO:0021761380.011
synaptic growth at neuromuscular junctionGO:005112410.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
neuromuscular processGO:005090520.011
wnt signaling pathway planar cell polarity pathwayGO:006007120.011
regulation of embryonic developmentGO:004599520.011
artery smooth muscle contractionGO:001482440.011
positive regulation of homeostatic processGO:0032846490.011
regulation of notch signaling pathwayGO:000859330.011
negative regulation of biosynthetic processGO:00098901680.011
cellular nitrogen compound catabolic processGO:00442701630.011
female gonad developmentGO:0008585530.011
peristalsisGO:003043220.011
eye developmentGO:0001654500.011
fatty acid metabolic processGO:0006631990.010
response to peptide hormoneGO:00434342780.010
positive regulation of epithelial cell proliferationGO:0050679320.010
cellular response to extracellular stimulusGO:0031668730.010

Tac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.036
disease of anatomical entityDOID:700.036
sensory system diseaseDOID:005015500.035
nervous system diseaseDOID:86300.035
bone development diseaseDOID:008000600.010
bone diseaseDOID:008000100.010
connective tissue diseaseDOID:6500.010