IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Rpl6

ribosomal protein L6

(Aliases: MGC93267)

Entrez: 117042
RGD: 619826
Ensembl: ENSRNOG00000025936
UniProtKB: P21533

Process Predictions
Disease Predictions

Rpl6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
translation	GO:0006412	35	0.501
mitotic spindle organization	GO:0007052	2	0.154
cellular component biogenesis	GO:0044085	368	0.117
ribonucleoprotein complex biogenesis	GO:0022613	10	0.082
organophosphate metabolic process	GO:0019637	370	0.081
macromolecular complex subunit organization	GO:0043933	339	0.074
rna metabolic process	GO:0016070	406	0.059
cellular amino acid metabolic process	GO:0006520	107	0.045
intracellular transport	GO:0046907	185	0.045
organelle organization	GO:0006996	266	0.042
carboxylic acid metabolic process	GO:0019752	289	0.040
cellular glucan metabolic process	GO:0006073	23	0.038
nucleoside triphosphate metabolic process	GO:0009141	144	0.037
single organism carbohydrate metabolic process	GO:0044723	118	0.037
ribonucleotide metabolic process	GO:0009259	231	0.034
response to glucose	GO:0009749	136	0.034
nucleoside phosphate metabolic process	GO:0006753	283	0.033
apoptotic process	GO:0006915	381	0.032
establishment of protein localization	GO:0045184	141	0.032
cellular ketone metabolic process	GO:0042180	51	0.032
regulation of membrane potential	GO:0042391	110	0.031
single organism reproductive process	GO:0044702	297	0.031
amine metabolic process	GO:0009308	38	0.031
cellular component assembly	GO:0022607	360	0.031
regulation of growth	GO:0040008	105	0.030
cytoplasmic transport	GO:0016482	115	0.030
nucleotide metabolic process	GO:0009117	279	0.030
positive regulation of cellular component biogenesis	GO:0044089	55	0.030
carbohydrate derivative metabolic process	GO:1901135	346	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.028
single organism catabolic process	GO:0044712	283	0.028
cellular polysaccharide biosynthetic process	GO:0033692	15	0.027
positive regulation of proteasomal protein catabolic process	GO:1901800	3	0.027
purine containing compound metabolic process	GO:0072521	253	0.027
positive regulation of molecular function	GO:0044093	230	0.027
regulation of purine nucleotide metabolic process	GO:1900542	115	0.027
regulation of catalytic activity	GO:0050790	304	0.027
motor neuron axon guidance	GO:0008045	1	0.026
regulation of molecular function	GO:0065009	398	0.026
programmed cell death	GO:0012501	392	0.025
polar body extrusion after meiotic divisions	GO:0040038	1	0.025
triglyceride homeostasis	GO:0070328	2	0.024
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.024
retina development in camera type eye	GO:0060041	27	0.023
purine containing compound catabolic process	GO:0072523	138	0.023
carbohydrate metabolic process	GO:0005975	130	0.023
epithelium development	GO:0060429	96	0.023
catabolic process	GO:0009056	351	0.022
nucleotide catabolic process	GO:0009166	139	0.022
reproductive process	GO:0022414	372	0.022
organic substance catabolic process	GO:1901575	316	0.022
gastrulation	GO:0007369	2	0.022
protein localization to organelle	GO:0033365	57	0.022
response to extracellular stimulus	GO:0009991	380	0.021
g protein coupled receptor signaling pathway	GO:0007186	242	0.021
single organism organelle organization	GO:1902589	180	0.021
oxoacid metabolic process	GO:0043436	290	0.021
regulation of neuron death	GO:1901214	115	0.021
ribosomal small subunit biogenesis	GO:0042274	6	0.021
hexose metabolic process	GO:0019318	58	0.021
intracellular signal transduction	GO:0035556	314	0.020
sexual reproduction	GO:0019953	148	0.020
generation of precursor metabolites and energy	GO:0006091	62	0.020
regulation of protein localization	GO:0032880	81	0.020
regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061178	14	0.020
protein complex subunit organization	GO:0071822	302	0.019
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.019
ribonucleoside metabolic process	GO:0009119	174	0.019
negative regulation of cellular biosynthetic process	GO:0031327	161	0.019
single organism intracellular transport	GO:1902582	166	0.018
regulation of protein localization to plasma membrane	GO:1903076	1	0.018
rrna processing	GO:0006364	2	0.018
cellular homeostasis	GO:0019725	252	0.018
protein oligomerization	GO:0051259	191	0.018
ribonucleotide catabolic process	GO:0009261	136	0.018
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.018
reproductive system development	GO:0061458	128	0.018
cellular protein localization	GO:0034613	122	0.018
vesicle mediated transport	GO:0016192	181	0.017
organic acid metabolic process	GO:0006082	292	0.017
nucleobase containing small molecule metabolic process	GO:0055086	316	0.017
regulation of anatomical structure size	GO:0090066	135	0.017
regulation of phosphate metabolic process	GO:0019220	349	0.017
purine ribonucleotide catabolic process	GO:0009154	136	0.017
tube development	GO:0035295	89	0.017
positive regulation of developmental process	GO:0051094	283	0.017
regulation of cellular amine metabolic process	GO:0033238	8	0.017
positive regulation of phosphate metabolic process	GO:0045937	262	0.016
multicellular organism reproduction	GO:0032504	233	0.016
macroautophagy	GO:0016236	4	0.016
cellular nitrogen compound catabolic process	GO:0044270	163	0.016
neuron differentiation	GO:0030182	368	0.016
regulation of cellular amino acid metabolic process	GO:0006521	2	0.016
posttranscriptional regulation of gene expression	GO:0010608	37	0.016
positive regulation of catabolic process	GO:0009896	78	0.016
spliceosomal complex assembly	GO:0000245	2	0.016
ribose phosphate metabolic process	GO:0019693	235	0.016
energy derivation by oxidation of organic compounds	GO:0015980	46	0.016
regulation of kinase activity	GO:0043549	117	0.016
ncrna processing	GO:0034470	3	0.016
translational initiation	GO:0006413	8	0.016
response to nutrient levels	GO:0031667	370	0.016
protein complex assembly	GO:0006461	263	0.016
nucleoside metabolic process	GO:0009116	179	0.016
nucleoside triphosphate catabolic process	GO:0009143	123	0.016
cytoplasmic translation	GO:0002181	1	0.015
regulation of multi organism process	GO:0043900	25	0.015
regulation of catabolic process	GO:0009894	113	0.015
regulation of cellular catabolic process	GO:0031329	101	0.015
peptidyl tyrosine modification	GO:0018212	72	0.015
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.015
regulation of protein oligomerization	GO:0032459	2	0.015
organelle fission	GO:0048285	25	0.015
nucleoside phosphate catabolic process	GO:1901292	140	0.015
localization of cell	GO:0051674	202	0.014
positive regulation of apoptotic process	GO:0043065	154	0.014
glucose metabolic process	GO:0006006	52	0.014
regulation of oxidative stress induced neuron death	GO:1903203	2	0.014
neuron death	GO:0070997	127	0.014
regulation of nucleotide catabolic process	GO:0030811	65	0.014
glycogen biosynthetic process	GO:0005978	15	0.014
guanosine containing compound metabolic process	GO:1901068	74	0.014
regulation of cellular component size	GO:0032535	51	0.014
response to inorganic substance	GO:0010035	377	0.014
purine ribonucleoside metabolic process	GO:0046128	168	0.014
macrophage differentiation	GO:0030225	1	0.014
gamete generation	GO:0007276	124	0.014
heterocycle catabolic process	GO:0046700	167	0.014
regulation of cellular localization	GO:0060341	263	0.014
ribosome biogenesis	GO:0042254	8	0.014
dephosphorylation	GO:0016311	98	0.013
cellular carbohydrate metabolic process	GO:0044262	72	0.013
organonitrogen compound catabolic process	GO:1901565	179	0.013
negative regulation of catalytic activity	GO:0043086	103	0.013
cellular response to external stimulus	GO:0071496	118	0.013
negative regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061179	6	0.013
negative regulation of cellular metabolic process	GO:0031324	281	0.013
negative regulation of protein modification by small protein conjugation or removal	GO:1903321	4	0.013
multicellular organismal reproductive process	GO:0048609	233	0.013
regulation of protein phosphorylation	GO:0001932	183	0.013
positive regulation of catalytic activity	GO:0043085	184	0.013
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	3	0.013
growth	GO:0040007	165	0.013
cellular iron ion homeostasis	GO:0006879	2	0.013
multicellular organism growth	GO:0035264	1	0.012
epithelial structure maintenance	GO:0010669	2	0.012
gtp catabolic process	GO:0006184	71	0.012
purine ribonucleoside catabolic process	GO:0046130	124	0.012
regulation of ion homeostasis	GO:2000021	63	0.012
regulation of hydrolase activity	GO:0051336	143	0.012
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	6	0.012
positive regulation of cell death	GO:0010942	184	0.012
regulation of purine nucleotide catabolic process	GO:0033121	65	0.012
positive regulation of cellular catabolic process	GO:0031331	71	0.012
monosaccharide metabolic process	GO:0005996	61	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
single organism biosynthetic process	GO:0044711	342	0.012
sex differentiation	GO:0007548	113	0.012
regulation of cellular component organization	GO:0051128	368	0.012
taxis	GO:0042330	67	0.012
dorsal ventral pattern formation	GO:0009953	4	0.012
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.012
smad protein import into nucleus	GO:0007184	3	0.012
positive regulation of protein oligomerization	GO:0032461	1	0.011
reproductive structure development	GO:0048608	128	0.011
acylglycerol homeostasis	GO:0055090	2	0.011
negative regulation of autophagy	GO:0010507	1	0.011
response to yeast	GO:0001878	3	0.011
developmental growth	GO:0048589	100	0.011
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	14	0.011
glucose 6 phosphate metabolic process	GO:0051156	11	0.011
axonogenesis	GO:0007409	71	0.011
cellular polysaccharide metabolic process	GO:0044264	23	0.011
cellular response to leptin stimulus	GO:0044320	6	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.011
cellular chemical homeostasis	GO:0055082	247	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.011
negative regulation of cell death	GO:0060548	229	0.010
female genitalia development	GO:0030540	3	0.010
reproduction	GO:0000003	245	0.010
cytoskeleton organization	GO:0007010	111	0.010
locomotion	GO:0040011	237	0.010
carbohydrate biosynthetic process	GO:0016051	42	0.010
fertilization	GO:0009566	3	0.010
positive regulation of cellular biosynthetic process	GO:0031328	295	0.010
negative regulation of biosynthetic process	GO:0009890	168	0.010
positive regulation of phosphorus metabolic process	GO:0010562	262	0.010

Rpl6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.020
disease of anatomical entity	DOID:7	0.020
connective tissue disease	DOID:65	0.020
disease of cellular proliferation	DOID:14566	0.016
benign neoplasm	DOID:0060072	0.016
organ system benign neoplasm	DOID:0060085	0.016

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