Rattus norvegicus

6 known processes

Fat2

FAT tumor suppressor homolog 2 (Drosophila)

(Aliases: Fath2)

Fat2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nucleic acid templated transcriptionGO:19035063800.556
response to estradiolGO:00323551640.552
intracellular signal transductionGO:00355563140.541
epithelium developmentGO:0060429960.523
tissue developmentGO:00098882520.444
neuron differentiationGO:00301823680.363
Worm
cellular response to organic cyclic compoundGO:00714072020.334
regulation of hormone levelsGO:00108171870.323
positive regulation of signal transductionGO:00099671750.307
response to nutrientGO:00075842480.281
cellular component assemblyGO:00226073600.281
response to estrogenGO:00436272320.267
negative regulation of nucleic acid templated transcriptionGO:19035071170.266
transcription dna templatedGO:00063513770.265
cellular response to oxygen containing compoundGO:19017013860.253
response to peptideGO:19016522920.241
response to extracellular stimulusGO:00099913800.237
reproductionGO:00000032450.230
positive regulation of cell proliferationGO:00082842490.229
single organism reproductive processGO:00447022970.222
anatomical structure morphogenesisGO:00096532980.221
Worm
reproductive processGO:00224143720.215
regulation of cell differentiationGO:00455953200.211
positive regulation of signalingGO:00230562700.201
regulation of molecular functionGO:00650093980.201
regulation of multicellular organismal developmentGO:20000263760.198
regulation of neuron differentiationGO:00456642080.196
regulation of signal transductionGO:00099663180.195
cellular response to hormone stimulusGO:00328702470.192
multi organism reproductive processGO:00447032620.189
regulation of cellular localizationGO:00603412630.189
response to inorganic substanceGO:00100353770.188
epithelial cell proliferationGO:0050673540.184
response to nutrient levelsGO:00316673700.175
g protein coupled receptor signaling pathwayGO:00071862420.174
negative regulation of cell proliferationGO:00082851190.173
regulation of rna metabolic processGO:00512523910.169
negative regulation of transcription dna templatedGO:00458921160.166
response to vitaminGO:00332731310.162
cell part morphogenesisGO:00329901230.161
Worm
localization of cellGO:00516742020.160
Human Worm
response to decreased oxygen levelsGO:00362932370.158
sexual reproductionGO:00199531480.153
central nervous system developmentGO:00074173110.151
defense responseGO:00069521940.149
response to other organismGO:00517072200.148
regulation of phosphorus metabolic processGO:00511743490.147
hormone secretionGO:00468791150.147
organ morphogenesisGO:0009887750.146
regulation of cell proliferationGO:00421273590.146
neuronal action potentialGO:0019228350.145
urogenital system developmentGO:0001655780.143
chemical homeostasisGO:00488782920.141
cellular component biogenesisGO:00440853680.141
regulation of membrane potentialGO:00423911100.133
multicellular organism reproductionGO:00325042330.131
sodium ion transmembrane transportGO:0035725670.128
regulation of transcription dna templatedGO:00063553740.128
cardiovascular system developmentGO:00723581340.128
response to peptide hormoneGO:00434342780.126
cell projection organizationGO:00300303020.126
Worm
heart morphogenesisGO:000300730.125
response to vitamin dGO:0033280340.122
head developmentGO:00603222470.121
lipid metabolic processGO:00066292830.121
ion homeostasisGO:00508012120.119
forebrain developmentGO:0030900980.113
cell migrationGO:00164771970.109
Human Worm
positive regulation of rna biosynthetic processGO:19026801970.109
striated muscle tissue developmentGO:0014706580.109
positive regulation of multicellular organismal processGO:00512403870.108
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.108
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.107
single organism biosynthetic processGO:00447113420.107
brain developmentGO:00074202470.104
response to biotic stimulusGO:00096072260.104
response to hypoxiaGO:00016662310.103
macromolecular complex subunit organizationGO:00439333390.103
regulation of phosphate metabolic processGO:00192203490.103
sodium ion transportGO:0006814820.103
cellular response to organonitrogen compoundGO:00714171970.101
negative regulation of nucleobase containing compound metabolic processGO:00459341530.101
regulation of system processGO:00440572080.100
cellular response to endogenous stimulusGO:00714953770.099
reproductive structure developmentGO:00486081280.097
glycosyl compound metabolic processGO:19016571820.095
transcription from rna polymerase ii promoterGO:00063662520.094
multicellular organismal reproductive processGO:00486092330.094
regulation of cell developmentGO:00602842630.094
rna biosynthetic processGO:00327743800.093
positive regulation of cell communicationGO:00106472710.092
locomotionGO:00400112370.091
Human Worm
regulation of intracellular signal transductionGO:19025312180.091
regulation of epithelial cell proliferationGO:0050678490.091
nucleic acid templated transcriptionGO:00976593790.089
regulation of protein metabolic processGO:00512462890.088
rna metabolic processGO:00160704060.088
developmental process involved in reproductionGO:00030061590.088
positive regulation of developmental processGO:00510942830.086
regulation of neurogenesisGO:00507672470.085
skeletal system developmentGO:0001501410.085
monocarboxylic acid metabolic processGO:00327871520.084
negative regulation of metabolic processGO:00098923310.084
negative regulation of cellular biosynthetic processGO:00313271610.084
tissue morphogenesisGO:0048729220.083
muscle system processGO:00030121150.083
negative regulation of rna metabolic processGO:00512531230.083
cation transportGO:00068123820.082
ion transmembrane transportGO:00342203650.081
response to bacteriumGO:00096172000.081
regulation of cellular component organizationGO:00511283680.080
neuron developmentGO:00486662860.080
Worm
negative regulation of biosynthetic processGO:00098901680.080
organelle organizationGO:00069962660.080
monovalent inorganic cation transportGO:00156721720.079
positive regulation of nucleobase containing compound metabolic processGO:00459353190.079
cellular response to stressGO:00335542690.078
metal ion homeostasisGO:00550651860.077
positive regulation of neurogenesisGO:00507691650.076
cellular response to lipidGO:00713962010.076
neuron projection developmentGO:00311752730.075
Worm
transmission of nerve impulseGO:0019226420.075
regulation of programmed cell deathGO:00430673410.073
regulation of ion transportGO:00432692450.073
action potentialGO:0001508540.072
nucleobase containing small molecule metabolic processGO:00550863160.071
regulation of blood circulationGO:19035221100.070
renal system developmentGO:0072001670.070
multicellular organismal signalingGO:0035637440.070
signal releaseGO:00230611450.070
positive regulation of cellular biosynthetic processGO:00313282950.069
negative regulation of signalingGO:00230571570.069
heart processGO:0003015570.069
response to external biotic stimulusGO:00432072210.067
negative regulation of response to stimulusGO:00485851550.067
cell motilityGO:00488702020.067
Human Worm
regulation of rna biosynthetic processGO:20011413810.066
positive regulation of cell differentiationGO:00455972170.065
nitrogen compound transportGO:00717052290.064
cell morphogenesisGO:00009021420.064
Worm
neurological system processGO:00508772190.063
cell cell signalingGO:00072673350.063
cellular response to nitrogen compoundGO:19016992100.063
cellular chemical homeostasisGO:00550822470.062
positive regulation of nitrogen compound metabolic processGO:00511733340.062
negative regulation of rna biosynthetic processGO:19026791180.062
response to reactive oxygen speciesGO:00003021200.061
negative regulation of nitrogen compound metabolic processGO:00511721610.059
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.059
response to insulinGO:00328681330.059
negative regulation of multicellular organismal processGO:00512412030.059
positive regulation of cell developmentGO:00107201760.059
positive regulation of gene expressionGO:00106282440.058
positive regulation of cellular protein metabolic processGO:00322701670.058
negative regulation of gene expressionGO:00106291990.057
response to hydrogen peroxideGO:0042542890.057
positive regulation of protein metabolic processGO:00512471780.057
negative regulation of cell communicationGO:00106481580.057
reproductive system developmentGO:00614581280.057
regulation of cellular protein metabolic processGO:00322682670.056
positive regulation of transcription dna templatedGO:00458931970.056
regulation of cyclic nucleotide metabolic processGO:0030799510.056
single organism catabolic processGO:00447122830.055
positive regulation of phosphate metabolic processGO:00459372620.055
response to molecule of bacterial originGO:00022371940.055
negative regulation of cellular metabolic processGO:00313242810.055
cellular component movementGO:00069282480.055
Human Worm
cell morphogenesis involved in neuron differentiationGO:00486671060.054
Worm
agingGO:00075682410.054
negative regulation of molecular functionGO:00440921330.054
mapk cascadeGO:00001651400.054
response to purine containing compoundGO:00140741260.053
purine containing compound metabolic processGO:00725212530.053
programmed cell deathGO:00125013920.053
circulatory system developmentGO:00723591340.053
vascular process in circulatory systemGO:0003018960.052
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.052
negative regulation of developmental processGO:00510931250.051
gonad developmentGO:00084061040.051
regulation of phosphorylationGO:00423252480.050
muscle cell proliferationGO:0033002840.050
gamete generationGO:00072761240.050
protein complex biogenesisGO:00702712630.050
response to woundingGO:00096112540.049
inorganic ion transmembrane transportGO:00986602290.049
regulation of nervous system developmentGO:00519602640.049
negative regulation of kidney developmentGO:009018520.049
circulatory system processGO:00030131830.049
negative regulation of cell differentiationGO:0045596990.049
protein complex assemblyGO:00064612630.048
metal ion transportGO:00300012890.048
blood circulationGO:00080151830.048
protein oligomerizationGO:00512591910.048
neuron projection morphogenesisGO:00488121220.048
Worm
cellular lipid metabolic processGO:00442552080.048
cellular response to growth factor stimulusGO:00713631620.047
cellular response to alcoholGO:0097306870.047
cellular homeostasisGO:00197252520.047
behaviorGO:00076102050.047
vesicle mediated transportGO:00161921810.046
organonitrogen compound biosynthetic processGO:19015661670.046
organic acid biosynthetic processGO:0016053830.046
negative regulation of secretionGO:0051048820.046
cellular response to external stimulusGO:00714961180.046
anion transportGO:00068201780.046
gland developmentGO:00487321550.046
epithelial cell differentiationGO:0030855710.046
apoptotic processGO:00069153810.045
learning or memoryGO:0007611900.045
regulation of blood vessel sizeGO:0050880890.045
response to glucocorticoidGO:00513842230.044
single organism organelle organizationGO:19025891800.044
rhythmic processGO:00485111560.044
kidney developmentGO:0001822670.044
positive regulation of biosynthetic processGO:00098913190.044
cellular response to peptide hormone stimulusGO:00713751200.043
positive regulation of nervous system developmentGO:00519621780.043
positive regulation of response to stimulusGO:00485842850.043
protein phosphorylationGO:00064683450.043
ovulation cycleGO:0042698670.043
negative regulation of neuron differentiationGO:0045665620.042
nucleoside phosphate metabolic processGO:00067532830.041
cellular response to cytokine stimulusGO:00713451270.041
multi multicellular organism processGO:00447061380.041
prostate gland epithelium morphogenesisGO:006074020.041
purine ribonucleotide metabolic processGO:00091502270.040
hormone metabolic processGO:0042445690.040
protein localizationGO:00081041910.040
cellular ketone metabolic processGO:0042180510.040
regulation of cellular ketone metabolic processGO:0010565270.038
response to oxygen levelsGO:00704822650.038
fatty acid metabolic processGO:0006631990.038
growthGO:00400071650.038
cell adhesionGO:00071551100.038
chemosensory behaviorGO:000763520.038
positive regulation of rna metabolic processGO:00512542030.038
gliogenesisGO:0042063930.038
morphogenesis of an epitheliumGO:0002009200.038
regulation of sodium ion transportGO:0002028210.037
amide transportGO:00428861050.037
smooth muscle cell proliferationGO:0048659770.037
small molecule biosynthetic processGO:00442831240.037
carboxylic acid biosynthetic processGO:0046394830.037
response to metal ionGO:00100382530.037
carbohydrate derivative metabolic processGO:19011353460.037
homeostatic processGO:00425923310.037
positive regulation of phosphorylationGO:00423271770.036
regulation of apoptotic processGO:00429813350.036
regulation of cell adhesionGO:0030155520.036
regulation of tube sizeGO:0035150890.036
regulation of anatomical structure sizeGO:00900661350.036
regulation of epithelial cell differentiationGO:0030856120.035
tongue morphogenesisGO:004358730.035
cell type specific apoptotic processGO:00972851340.035
biological adhesionGO:00226101100.035
intracellular transportGO:00469071850.035
regulation of neuron projection developmentGO:00109751610.035
response to ethanolGO:00454711620.034
regulation of nucleotide metabolic processGO:00061401170.034
small gtpase mediated signal transductionGO:0007264360.034
cytokine mediated signaling pathwayGO:0019221430.034
axon ensheathmentGO:0008366400.033
male sex differentiationGO:0046661640.033
positive regulation of molecular functionGO:00440932300.033
cellular catabolic processGO:00442482950.033
potassium ion transportGO:0006813970.032
regulation of peptide hormone secretionGO:0090276800.032
ribose phosphate metabolic processGO:00196932350.032
positive regulation of cell deathGO:00109421840.032
single organism intracellular transportGO:19025821660.032
odontogenesisGO:0042476320.032
negative regulation of cell developmentGO:0010721820.032
regulation of hormone secretionGO:00468831060.032
secretion by cellGO:00329402480.031
lipid biosynthetic processGO:00086101280.031
regulation of peptide transportGO:0090087870.031
synaptic transmission gabaergicGO:0051932220.031
single organism behaviorGO:00447081300.031
motor neuron axon guidanceGO:000804510.031
heart developmentGO:0007507720.031
ribonucleotide metabolic processGO:00092592310.031
cognitionGO:0050890920.031
cell projection morphogenesisGO:00488581230.031
Worm
cell morphogenesis involved in differentiationGO:00009041190.031
Worm
response to oxidative stressGO:00069791860.031
positive regulation of macromolecule biosynthetic processGO:00105572470.030
response to growth factorGO:00708481890.030
purine nucleotide biosynthetic processGO:0006164830.030
cation homeostasisGO:00550801950.030
cellular component morphogenesisGO:00329891550.030
Worm
positive regulation of cell motilityGO:2000147970.030
female pregnancyGO:00075651220.029
positive regulation of catalytic activityGO:00430851840.029
positive regulation of programmed cell deathGO:00430681570.029
muscle structure developmentGO:0061061870.029
negative regulation of macromolecule metabolic processGO:00106052600.029
chlorinated hydrocarbon metabolic processGO:004219640.029
positive regulation of intracellular signal transductionGO:19025331380.029
immune system processGO:00023762040.029
cellular response to peptideGO:19016531330.028
ensheathment of neuronsGO:0007272400.028
protein complex subunit organizationGO:00718223020.028
regulation of metal ion transportGO:00109591180.028
positive regulation of cellular amino acid metabolic processGO:004576410.028
tube developmentGO:0035295890.027
muscle tissue developmentGO:0060537580.027
axon developmentGO:0061564960.027
Worm
calcitriol biosynthetic process from calciolGO:003637820.027
secretionGO:00469033070.027
response to cytokineGO:00340972150.027
response to mechanical stimulusGO:00096121340.027
regulation of catalytic activityGO:00507903040.027
cellular response to drugGO:0035690300.027
nucleotide metabolic processGO:00091172790.027
peptide secretionGO:0002790860.027
inorganic cation transmembrane transportGO:00986622020.027
positive regulation of transportGO:00510502450.027
vesicle localizationGO:0051648330.026
ovulation cycle processGO:0022602500.026
positive regulation of cellular amine metabolic processGO:003324030.026
response to alkaloidGO:00432791320.026
negative regulation of cell deathGO:00605482290.026
development of primary sexual characteristicsGO:00451371070.026
regulation of exocytosisGO:0017157370.026
regulation of cell projection organizationGO:00313441750.026
regulation of insulin secretionGO:0050796650.026
organic acid metabolic processGO:00060822920.026
insulin secretionGO:0030073690.026
macromolecular complex assemblyGO:00650032730.026
peptide hormone secretionGO:0030072840.025
response to retinoic acidGO:0032526630.025
isoprenoid metabolic processGO:0006720450.025
multicellular organismal homeostasisGO:0048871490.025
inflammatory responseGO:00069541500.025
myelinationGO:0042552390.025
regulation of secretionGO:00510462240.025
synaptic transmission glycinergicGO:006001220.025
cellular metal ion homeostasisGO:00068751720.025
regulation of hydrolase activityGO:00513361430.025
oxidation reduction processGO:00551143040.025
single organism cellular localizationGO:19025801020.025
regulation of synaptic transmissionGO:00508041410.025
cellular macromolecule localizationGO:00707271220.025
cellular response to steroid hormone stimulusGO:0071383930.024
response to lipopolysaccharideGO:00324961910.024
wound healingGO:00420601220.024
sex differentiationGO:00075481130.024
sensory organ developmentGO:0007423740.024
neuron neuron synaptic transmissionGO:0007270600.024
cellular response to abiotic stimulusGO:0071214850.024
purine ribonucleotide biosynthetic processGO:0009152810.024
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
cellular hormone metabolic processGO:0034754490.024
ras protein signal transductionGO:0007265290.024
regulation of cellular component movementGO:00512701500.024
catabolic processGO:00090563510.023
olfactory behaviorGO:004204820.023
response to hyperoxiaGO:0055093450.023
regulation of cellular amino acid metabolic processGO:000652120.023
carboxylic acid metabolic processGO:00197522890.023
telencephalon developmentGO:0021537620.023
glial cell differentiationGO:0010001650.022
embryonic skeletal system developmentGO:004870630.022
regulation of anatomical structure morphogenesisGO:00226031410.022
development of primary female sexual characteristicsGO:0046545560.022
organophosphate metabolic processGO:00196373700.022
regulation of cellular amine metabolic processGO:003323880.022
regulation of protein phosphorylationGO:00019321830.022
negative regulation of peptide hormone secretionGO:0090278300.022
negative regulation of secretion by cellGO:1903531720.022
reactive oxygen species biosynthetic processGO:190340980.022
mammary gland morphogenesisGO:006044360.022
organic anion transportGO:00157111320.022
connective tissue developmentGO:0061448330.021
vasodilationGO:0042311440.021
negative regulation of apoptotic processGO:00430661810.021
response to acid chemicalGO:00011012220.021
erk1 and erk2 cascadeGO:0070371480.021
second messenger mediated signalingGO:0019932510.021
positive regulation of apoptotic processGO:00430651540.021
chemotaxisGO:0006935660.021
Worm
vitamin biosynthetic processGO:000911030.021
activation of jak2 kinase activityGO:004297720.021
secondary alcohol metabolic processGO:190265220.021
spermatogenesisGO:0007283990.020
regulation of kidney developmentGO:0090183150.020
proteolysisGO:00065081750.020
organic cyclic compound catabolic processGO:19013611750.020
regulation of smooth muscle cell proliferationGO:0048660750.020
cellular calcium ion homeostasisGO:00068741600.020
negative regulation of programmed cell deathGO:00430691830.020
negative regulation of cellular component organizationGO:0051129830.020
cellular response to nutrient levelsGO:0031669600.020
purine nucleoside metabolic processGO:00422781690.020
response to axon injuryGO:0048678590.020
regulation of vesicle mediated transportGO:0060627810.020
ribonucleoside metabolic processGO:00091191740.020
lipid storageGO:001991510.020
regulation of cell morphogenesis involved in differentiationGO:0010769720.020
monocarboxylic acid biosynthetic processGO:0072330480.020
neuron deathGO:00709971270.020
reactive oxygen species metabolic processGO:0072593370.020
bone developmentGO:0060348250.020
male mating behaviorGO:006017930.019
cellular ion homeostasisGO:00068731840.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
positive regulation of protein modification processGO:00314011420.019
cardiac muscle contractionGO:0060048270.019
hormone mediated signaling pathwayGO:0009755230.019
steroid metabolic processGO:0008202730.019
regulation of locomotionGO:00400121480.019
regulation of systemic arterial blood pressureGO:0003073300.019
jak stat cascadeGO:0007259260.019
regulation of jak stat cascadeGO:0046425210.019
cellular cation homeostasisGO:00300031800.019
cellular amino acid metabolic processGO:00065201070.019
response to hexoseGO:00097461440.019
regulation of heart contractionGO:0008016480.018
dendrite developmentGO:0016358720.018
positive regulation of neuron differentiationGO:00456661260.018
regulation of cell motilityGO:20001451310.018
peptidyl amino acid modificationGO:00181931260.018
dendrite morphogenesisGO:0048813430.018
hematopoietic progenitor cell differentiationGO:000224420.018
regulation of vasoconstrictionGO:0019229440.018
tissue remodelingGO:0048771400.018
heterocycle catabolic processGO:00467001670.017
cytoskeleton organizationGO:00070101110.017
regulation of stem cell proliferationGO:0072091140.017
organic substance catabolic processGO:19015753160.017
positive regulation of cellular component organizationGO:00511302000.017
response to corticosteroidGO:00319602350.017
vasoconstrictionGO:0042310540.017
single organism cell adhesionGO:0098602460.017
regulation of metanephros developmentGO:007221540.017
regulation of organelle organizationGO:0033043800.017
olfactory learningGO:000835510.017
establishment of protein localizationGO:00451841410.017
regulation of purine nucleotide metabolic processGO:19005421150.017
protein homooligomerizationGO:0051260910.017
cation transmembrane transportGO:00986552630.017
negative regulation of catalytic activityGO:00430861030.017
cellular response to hexose stimulusGO:0071331650.017
adult locomotory behaviorGO:000834440.017
ribonucleotide biosynthetic processGO:0009260850.017
regulation of homeostatic processGO:00328441010.017
response to carbohydrateGO:00097431830.016
neuron apoptotic processGO:0051402880.016
heart contractionGO:0060047570.016
male gamete generationGO:0048232990.016
cellular response to oxidative stressGO:0034599760.016
carbohydrate homeostasisGO:0033500750.016
purine nucleotide metabolic processGO:00061632290.016
fatty acid derivative metabolic processGO:1901568380.016
ossificationGO:0001503700.016
regulation of protein modification processGO:00313991940.016
sensory perceptionGO:00076001010.015
positive regulation of cell projection organizationGO:00313461110.015
acute inflammatory responseGO:0002526580.015
negative regulation of cardiac muscle tissue developmentGO:005502630.015
icosanoid metabolic processGO:0006690380.015
nucleoside metabolic processGO:00091161790.015
response to testosteroneGO:0033574550.015
response to toxic substanceGO:00096361330.015
response to ammonium ionGO:0060359710.015
peptide transportGO:0015833970.015
regulation of nucleotide biosynthetic processGO:0030808470.015
positive regulation of ion transportGO:0043270940.015
purine containing compound biosynthetic processGO:0072522850.015
autonomic nervous system developmentGO:004848330.015
macromolecule localizationGO:00330362520.015
organonitrogen compound catabolic processGO:19015651790.015
regulation of purine nucleotide biosynthetic processGO:1900371460.015
neuromuscular processGO:005090520.014
mesenchymal to epithelial transitionGO:006023130.014
regulation of muscle system processGO:0090257790.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
cellular response to glucocorticoid stimulusGO:0071385680.014
cellular response to carbohydrate stimulusGO:0071322720.014
response to increased oxygen levelsGO:0036296450.014
epibolyGO:009050420.014
regulation of growthGO:00400081050.014
cellular response to corticosteroid stimulusGO:0071384690.014
negative regulation of metanephros developmentGO:007221720.014
muscle contractionGO:0006936880.014
positive regulation of blood circulationGO:1903524650.014
calcium ion homeostasisGO:00550741620.014
cellular protein localizationGO:00346131220.014
terpenoid metabolic processGO:0006721370.014

Fat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
gastrointestinal system diseaseDOID:7700.030
musculoskeletal system diseaseDOID:1700.026
nervous system diseaseDOID:86300.019
central nervous system diseaseDOID:33100.015
disease of cellular proliferationDOID:1456600.015