IMP: Integrative Multi-species Prediction

Rattus norvegicus

26 known processes

Scpep1

serine carboxypeptidase 1

(Aliases: Risc)

RGD: 620067
Entrez: 114861
Ensembl: ENSRNOG00000002358
UniProtKB: Q920A6

Process Predictions
Disease Predictions

Scpep1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
multicellular organism reproduction	GO:0032504	233	0.080
catabolic process	GO:0009056	351	0.071
organic substance catabolic process	GO:1901575	316	0.068
regulation of cellular component organization	GO:0051128	368	0.067
apoptotic process	GO:0006915	381	0.058
reproductive process	GO:0022414	372	0.057
positive regulation of multicellular organismal process	GO:0051240	387	0.057
oxoacid metabolic process	GO:0043436	290	0.057
organic acid metabolic process	GO:0006082	292	0.055
homeostatic process	GO:0042592	331	0.055
carbohydrate derivative metabolic process	GO:1901135	346	0.052
cellular catabolic process	GO:0044248	295	0.048
response to corticosteroid	GO:0031960	235	0.042
proteolysis	GO:0006508	175	0.041
response to acid chemical	GO:0001101	222	0.041
cellular amino acid metabolic process	GO:0006520	107	0.040
multi organism reproductive process	GO:0044703	262	0.040
regulation of multicellular organismal development	GO:2000026	376	0.038
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.037
lung development	GO:0030324	43	0.034
reproductive system development	GO:0061458	128	0.033
response to extracellular stimulus	GO:0009991	380	0.033
positive regulation of developmental process	GO:0051094	283	0.032
negative regulation of multicellular organismal process	GO:0051241	203	0.032
lipid metabolic process	GO:0006629	283	0.031
protein transport	GO:0015031	132	0.031
macromolecule localization	GO:0033036	252	0.031
secretion	GO:0046903	307	0.030
cellular response to endogenous stimulus	GO:0071495	377	0.030
vasculature development	GO:0001944	70	0.030
protein localization	GO:0008104	191	0.030
respiratory system development	GO:0060541	45	0.029
positive regulation of cell development	GO:0010720	176	0.029
circulatory system development	GO:0072359	134	0.028
programmed cell death	GO:0012501	392	0.027
carboxylic acid metabolic process	GO:0019752	289	0.027
anatomical structure morphogenesis	GO:0009653	298	0.026
amine metabolic process	GO:0009308	38	0.026
response to peptide hormone	GO:0043434	278	0.025
multicellular organismal reproductive process	GO:0048609	233	0.025
vesicle mediated transport	GO:0016192	181	0.024
regulation of bmp signaling pathway	GO:0030510	2	0.024
chemical homeostasis	GO:0048878	292	0.024
response to nutrient levels	GO:0031667	370	0.024
response to estrogen	GO:0043627	232	0.024
single organism reproductive process	GO:0044702	297	0.023
reproduction	GO:0000003	245	0.023
negative regulation of cell death	GO:0060548	229	0.023
regulation of cell proliferation	GO:0042127	359	0.023
establishment of protein localization	GO:0045184	141	0.023
cardiovascular system development	GO:0072358	134	0.023
bmp signaling pathway	GO:0030509	4	0.022
ossification	GO:0001503	70	0.022
positive regulation of cell differentiation	GO:0045597	217	0.022
regulation of phosphorylation	GO:0042325	248	0.021
regulation of protein localization	GO:0032880	81	0.021
organonitrogen compound biosynthetic process	GO:1901566	167	0.021
regulation of neuron differentiation	GO:0045664	208	0.020
regulation of secretion	GO:0051046	224	0.020
regulation of molecular function	GO:0065009	398	0.019
response to monosaccharide	GO:0034284	159	0.019
regulation of cellular amine metabolic process	GO:0033238	8	0.019
intracellular signal transduction	GO:0035556	314	0.019
response to metal ion	GO:0010038	253	0.019
g protein coupled receptor signaling pathway	GO:0007186	242	0.019
cellular lipid metabolic process	GO:0044255	208	0.019
tube development	GO:0035295	89	0.019
regulation of cellular localization	GO:0060341	263	0.018
cellular amine metabolic process	GO:0044106	38	0.018
cellular amide metabolic process	GO:0043603	44	0.018
regulation of protein metabolic process	GO:0051246	289	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
positive regulation of cellular protein metabolic process	GO:0032270	167	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.018
regulation of catalytic activity	GO:0050790	304	0.018
sexual reproduction	GO:0019953	148	0.017
urogenital system development	GO:0001655	78	0.017
response to ethanol	GO:0045471	162	0.017
cellular ketone metabolic process	GO:0042180	51	0.016
transcription from rna polymerase ii promoter	GO:0006366	252	0.016
secretion by cell	GO:0032940	248	0.016
circulatory system process	GO:0003013	183	0.016
single organism catabolic process	GO:0044712	283	0.016
response to estradiol	GO:0032355	164	0.016
respiratory tube development	GO:0030323	43	0.016
regulation of body fluid levels	GO:0050878	90	0.016
negative regulation of vasculature development	GO:1901343	11	0.015
regulation of establishment of protein localization	GO:0070201	69	0.015
regulation of protein transport	GO:0051223	68	0.015
response to carbohydrate	GO:0009743	183	0.015
signal transduction by phosphorylation	GO:0023014	144	0.015
organ regeneration	GO:0031100	101	0.015
organ morphogenesis	GO:0009887	75	0.015
positive regulation of nervous system development	GO:0051962	178	0.015
steroid metabolic process	GO:0008202	73	0.014
response to radiation	GO:0009314	137	0.014
response to retinoic acid	GO:0032526	63	0.014
tissue development	GO:0009888	252	0.014
neuron projection development	GO:0031175	273	0.014
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
positive regulation of neuron differentiation	GO:0045666	126	0.014
response to inorganic substance	GO:0010035	377	0.014
positive regulation of signaling	GO:0023056	270	0.014
synaptic transmission	GO:0007268	235	0.014
response to glucocorticoid	GO:0051384	223	0.014
positive regulation of cell projection organization	GO:0031346	111	0.014
regulation of apoptotic process	GO:0042981	335	0.013
dna replication	GO:0006260	37	0.013
regulation of cell development	GO:0060284	263	0.013
negative regulation of transport	GO:0051051	136	0.013
regulation of cell differentiation	GO:0045595	320	0.013
macromolecular complex subunit organization	GO:0043933	339	0.013
positive regulation of cell proliferation	GO:0008284	249	0.013
response to peptide	GO:1901652	292	0.013
response to glucose	GO:0009749	136	0.013
regulation of phosphorus metabolic process	GO:0051174	349	0.013
response to hexose	GO:0009746	144	0.013
positive regulation of protein modification process	GO:0031401	142	0.012
monocarboxylic acid metabolic process	GO:0032787	152	0.012
cellular component assembly	GO:0022607	360	0.012
regulation of signal transduction	GO:0009966	318	0.012
positive regulation of protein metabolic process	GO:0051247	178	0.012
multicellular organism growth	GO:0035264	1	0.012
cellular component movement	GO:0006928	248	0.012
regulation of system process	GO:0044057	208	0.012
head development	GO:0060322	247	0.012
negative regulation of developmental process	GO:0051093	125	0.012
nucleobase containing small molecule metabolic process	GO:0055086	316	0.012
regulation of response to stress	GO:0080134	126	0.012
single organism biosynthetic process	GO:0044711	342	0.012
female pregnancy	GO:0007565	122	0.012
regeneration	GO:0031099	163	0.012
angiogenesis	GO:0001525	53	0.012
male gamete generation	GO:0048232	99	0.012
regulation of cellular protein metabolic process	GO:0032268	267	0.011
regulation of epithelial cell proliferation	GO:0050678	49	0.011
neuron differentiation	GO:0030182	368	0.011
kidney development	GO:0001822	67	0.011
response to fluoride	GO:1902617	3	0.011
sulfur compound catabolic process	GO:0044273	3	0.011
neuron development	GO:0048666	286	0.011
neuron death	GO:0070997	127	0.011
protein oligomerization	GO:0051259	191	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
regulation of nervous system development	GO:0051960	264	0.011
negative regulation of neuron death	GO:1901215	69	0.011
metal ion homeostasis	GO:0055065	186	0.011
positive regulation of response to stimulus	GO:0048584	285	0.011
cell cell signaling	GO:0007267	335	0.011
negative regulation of innate immune response	GO:0045824	4	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011
regulation of dendrite development	GO:0050773	59	0.011
liver development	GO:0001889	90	0.011
positive regulation of cell death	GO:0010942	184	0.011
organic acid biosynthetic process	GO:0016053	83	0.011
carbohydrate derivative biosynthetic process	GO:1901137	124	0.011
protein phosphorylation	GO:0006468	345	0.011
cell projection organization	GO:0030030	302	0.011
peptidyl amino acid modification	GO:0018193	126	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
nucleic acid templated transcription	GO:0097659	379	0.011
positive regulation of phosphorylation	GO:0042327	177	0.010
organophosphate metabolic process	GO:0019637	370	0.010
positive regulation of cellular component organization	GO:0051130	200	0.010
multi multicellular organism process	GO:0044706	138	0.010
gamete generation	GO:0007276	124	0.010
negative regulation of gene expression	GO:0010629	199	0.010
regulation of neuron death	GO:1901214	115	0.010
regulation of immune system process	GO:0002682	123	0.010
regulation of protein modification process	GO:0031399	194	0.010
mapk cascade	GO:0000165	140	0.010
regulation of neurogenesis	GO:0050767	247	0.010
regulation of hormone levels	GO:0010817	187	0.010
male mating behavior	GO:0060179	3	0.010

Scpep1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.214
disease of metabolism	DOID:0014667	0.214
lipid storage disease	DOID:9455	0.214
lysosomal storage disease	DOID:3211	0.214
nervous system disease	DOID:863	0.100
disease of anatomical entity	DOID:7	0.100
brain disease	DOID:936	0.099
central nervous system disease	DOID:331	0.099
cerebral degeneration	DOID:1443	0.099
musculoskeletal system disease	DOID:17	0.024
connective tissue disease	DOID:65	0.020
sensory system disease	DOID:0050155	0.018
eye and adnexa disease	DOID:1492	0.018
eye disease	DOID:5614	0.016

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