Rattus norvegicus

0 known processes

Nrl

neural retina leucine zipper

Nrl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
metal ion transportGO:00300012890.293
cellular response to lipidGO:00713962010.217
ion transmembrane transportGO:00342203650.201
head developmentGO:00603222470.183
behaviorGO:00076102050.180
cellular response to organic cyclic compoundGO:00714072020.169
positive regulation of phosphorylationGO:00423271770.168
neurological system processGO:00508772190.168
sensory perception of painGO:0019233730.161
organ morphogenesisGO:0009887750.149
Fly
cation transportGO:00068123820.139
cellular component biogenesisGO:00440853680.134
brain developmentGO:00074202470.132
cellular response to steroid hormone stimulusGO:0071383930.129
anatomical structure morphogenesisGO:00096532980.129
Fly
transmembrane transportGO:00550854120.128
regulation of phosphate metabolic processGO:00192203490.124
central nervous system developmentGO:00074173110.115
cation transmembrane transportGO:00986552630.115
protein complex assemblyGO:00064612630.113
inorganic cation transmembrane transportGO:00986622020.111
regulation of signal transductionGO:00099663180.105
regulation of rna metabolic processGO:00512523910.098
Rat Fly
forebrain developmentGO:0030900980.098
cellular metal ion homeostasisGO:00068751720.094
neuron differentiationGO:00301823680.085
response to radiationGO:00093141370.085
positive regulation of phosphorus metabolic processGO:00105622620.082
protein complex subunit organizationGO:00718223020.080
locomotionGO:00400112370.079
Fly
regulation of phosphorylationGO:00423252480.078
retina morphogenesis in camera type eyeGO:006004210.078
macromolecular complex assemblyGO:00650032730.077
regulation of behaviorGO:0050795610.076
eye morphogenesisGO:004859240.076
choline transportGO:001587140.071
cellular response to endogenous stimulusGO:00714953770.071
somatostatin receptor signaling pathwayGO:003816940.070
positive regulation of cellular biosynthetic processGO:00313282950.069
Rat Fly
macromolecule localizationGO:00330362520.069
regulation of phosphorus metabolic processGO:00511743490.069
cellular component assemblyGO:00226073600.066
positive regulation of nitrogen compound metabolic processGO:00511733340.065
Rat Fly
regulation of secretionGO:00510462240.063
cellular calcium ion homeostasisGO:00068741600.063
positive regulation of protein metabolic processGO:00512471780.063
neuron developmentGO:00486662860.061
positive regulation of response to stimulusGO:00485842850.061
synaptic transmissionGO:00072682350.061
regulation of ion transportGO:00432692450.061
somatostatin signaling pathwayGO:003817040.060
cellular ion homeostasisGO:00068731840.059
positive regulation of transportGO:00510502450.059
response to corticosteroidGO:00319602350.057
secretionGO:00469033070.057
tissue developmentGO:00098882520.055
Fly
nucleotide metabolic processGO:00091172790.052
detection of visible lightGO:000958430.051
homeostatic processGO:00425923310.051
macromolecular complex subunit organizationGO:00439333390.051
regulation of system processGO:00440572080.051
metestrusGO:006021010.050
regulation of cellular localizationGO:00603412630.050
gastric motilityGO:003548230.050
positive regulation of intracellular signal transductionGO:19025331380.049
lipid transportGO:0006869610.049
nitrogen compound transportGO:00717052290.049
rna biosynthetic processGO:00327743800.048
Rat Fly
hormone transportGO:00099141210.048
positive regulation of macromolecule biosynthetic processGO:00105572470.047
Rat Fly
regulation of multicellular organismal developmentGO:20000263760.047
secretion by cellGO:00329402480.047
purine nucleotide metabolic processGO:00061632290.046
positive regulation of protein kinase activityGO:0045860730.046
startle responseGO:000196420.046
response to histamineGO:003477630.045
nucleoside phosphate metabolic processGO:00067532830.045
positive regulation of nucleobase containing compound metabolic processGO:00459353190.045
Rat Fly
response to cytokineGO:00340972150.044
signal transduction by phosphorylationGO:00230141440.044
feeding behaviorGO:0007631530.044
positive regulation of cell proliferationGO:00082842490.044
tube developmentGO:0035295890.043
regulation of intracellular signal transductionGO:19025312180.043
divalent inorganic cation transportGO:00725111340.043
heart contractionGO:0060047570.042
regulation of protein metabolic processGO:00512462890.042
carbohydrate derivative biosynthetic processGO:19011371240.042
carbohydrate derivative metabolic processGO:19011353460.040
response to oxygen levelsGO:00704822650.040
regulation of cellular component movementGO:00512701500.040
single organism behaviorGO:00447081300.040
ion homeostasisGO:00508012120.040
positive regulation of cell communicationGO:00106472710.039
regulation of cell differentiationGO:00455953200.039
hormone secretionGO:00468791150.039
positive regulation of protein modification processGO:00314011420.039
muscle system processGO:00030121150.038
rhythmic processGO:00485111560.038
positive regulation of biosynthetic processGO:00098913190.038
Rat Fly
organic acid metabolic processGO:00060822920.037
intracellular signal transductionGO:00355563140.037
programmed cell deathGO:00125013920.036
response to acid chemicalGO:00011012220.036
purine ribonucleoside triphosphate catabolic processGO:00092071220.036
negative regulation of apoptotic processGO:00430661810.036
action potentialGO:0001508540.035
g protein coupled receptor signaling pathwayGO:00071862420.035
response to light stimulusGO:0009416520.035
cell cell signalingGO:00072673350.034
nucleobase containing small molecule metabolic processGO:00550863160.034
response to ethanolGO:00454711620.034
protein oligomerizationGO:00512591910.033
response to estradiolGO:00323551640.033
response to peptide hormoneGO:00434342780.033
positive regulation of gene expressionGO:00106282440.033
Rat Fly
metal ion homeostasisGO:00550651860.033
protein complex biogenesisGO:00702712630.032
response to extracellular stimulusGO:00099913800.032
regulation of protein modification processGO:00313991940.032
organonitrogen compound biosynthetic processGO:19015661670.032
single organism biosynthetic processGO:00447113420.032
regulation of mapk cascadeGO:00434081160.032
cell projection organizationGO:00300303020.031
cation homeostasisGO:00550801950.031
response to alkaloidGO:00432791320.031
phasic smooth muscle contractionGO:001482130.031
anion transportGO:00068201780.031
neuropeptide signaling pathwayGO:0007218290.031
regulation of rna biosynthetic processGO:20011413810.030
Rat Fly
cellular divalent inorganic cation homeostasisGO:00725031620.030
positive regulation of molecular functionGO:00440932300.030
regulation of nucleic acid templated transcriptionGO:19035063800.029
Rat Fly
cellular response to histamineGO:007142030.029
protein phosphorylationGO:00064683450.028
regulation of apoptotic processGO:00429813350.028
response to ketoneGO:19016541820.028
sensory perceptionGO:00076001010.028
response to peptideGO:19016522920.028
cellular response to hormone stimulusGO:00328702470.028
regulation of cellular protein metabolic processGO:00322682670.028
nucleoside phosphate biosynthetic processGO:19012931020.028
positive regulation of mapk cascadeGO:0043410920.028
positive regulation of multicellular organismal processGO:00512403870.027
cellular chemical homeostasisGO:00550822470.027
divalent metal ion transportGO:00708381320.027
signal releaseGO:00230611450.027
urogenital system developmentGO:0001655780.027
positive regulation of ion transportGO:0043270940.027
camera type eye morphogenesisGO:004859320.027
regulation of purine nucleotide metabolic processGO:19005421150.027
regulation of nucleotide metabolic processGO:00061401170.026
positive regulation of catalytic activityGO:00430851840.026
transcription dna templatedGO:00063513770.026
Rat Fly
response to estrogenGO:00436272320.026
cognitionGO:0050890920.026
positive regulation of secretionGO:00510471400.026
maintenance of locationGO:0051235170.026
gonad developmentGO:00084061040.025
Fly
ribonucleotide metabolic processGO:00092592310.025
development of primary sexual characteristicsGO:00451371070.025
Fly
apoptotic processGO:00069153810.025
calcium ion transportGO:00068161310.025
positive regulation of signalingGO:00230562700.025
cellular amine metabolic processGO:0044106380.025
positive regulation of hormone secretionGO:0046887650.025
response to decreased oxygen levelsGO:00362932370.024
nucleic acid templated transcriptionGO:00976593790.024
Rat Fly
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
Rat Fly
positive regulation of nucleotide metabolic processGO:0045981910.024
positive regulation of signal transductionGO:00099671750.024
development of primary female sexual characteristicsGO:0046545560.024
Fly
mapk cascadeGO:00001651400.023
ribose phosphate metabolic processGO:00196932350.023
peristalsisGO:003043220.023
protein homooligomerizationGO:0051260910.023
neuron projection developmentGO:00311752730.023
response to growth factorGO:00708481890.023
phenol containing compound metabolic processGO:0018958300.023
ovulation cycleGO:0042698670.023
blood circulationGO:00080151830.023
negative regulation of luteinizing hormone secretionGO:003368540.023
negative regulation of secretion by cellGO:1903531720.023
vesicle mediated transportGO:00161921810.023
establishment of protein localizationGO:00451841410.022
regulation of membrane potentialGO:00423911100.022
multicellular organismal response to stressGO:0033555250.022
cellular cation homeostasisGO:00300031800.022
regulation of hormone levelsGO:00108171870.022
negative regulation of cell deathGO:00605482290.022
single organism reproductive processGO:00447022970.022
Fly
positive regulation of kinase activityGO:0033674770.022
negative regulation of multicellular organismal processGO:00512412030.021
cellular response to oxygen containing compoundGO:19017013860.021
response to nutrient levelsGO:00316673700.021
cellular response to nitrogen compoundGO:19016992100.021
lipid metabolic processGO:00066292830.021
glycosyl compound metabolic processGO:19016571820.021
sensory organ developmentGO:0007423740.021
digestive system processGO:0022600240.021
regulation of sodium ion transmembrane transporter activityGO:200064940.021
regulation of cyclic nucleotide metabolic processGO:0030799510.021
catabolic processGO:00090563510.021
unsaturated fatty acid metabolic processGO:0033559390.021
organ regenerationGO:00311001010.020
regulation of cellular amino acid metabolic processGO:000652120.020
positive regulation of rna metabolic processGO:00512542030.020
Rat Fly
cellular component movementGO:00069282480.020
Fly
amide transportGO:00428861050.020
locomotory behaviorGO:0007626150.020
positive regulation of calcium ion transportGO:0051928360.020
positive regulation of phosphate metabolic processGO:00459372620.020
response to ammonium ionGO:0060359710.020
positive regulation of rna biosynthetic processGO:19026801970.020
Rat Fly
wnt signaling pathway planar cell polarity pathwayGO:006007120.020
inorganic ion transmembrane transportGO:00986602290.020
adult locomotory behaviorGO:000834440.019
single organism cellular localizationGO:19025801020.019
purine ribonucleoside metabolic processGO:00461281680.019
phototransduction visible lightGO:000760320.019
cellular catabolic processGO:00442482950.019
regulation of erk1 and erk2 cascadeGO:0070372410.019
regulation of establishment of planar polarityGO:009017520.019
cellular response to ammonium ionGO:0071242170.019
regulation of muscle system processGO:0090257790.019
response to transition metal nanoparticleGO:19902671220.019
cell motilityGO:00488702020.018
Fly
positive regulation of heart contractionGO:0045823150.018
reproductive system developmentGO:00614581280.018
Fly
regulation of saliva secretionGO:004687730.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
multicellular organismal reproductive processGO:00486092330.018
Fly
cytosolic calcium ion homeostasisGO:00514801400.018
trichloroethylene metabolic processGO:001897910.018
phenol containing compound biosynthetic processGO:004618990.018
neuromuscular processGO:005090520.018
synaptic transmission glycinergicGO:006001220.018
heart processGO:0003015570.018
regulation of cyclase activityGO:0031279210.018
response to testosteroneGO:0033574550.018
synaptic transmission cholinergicGO:0007271110.018
organelle organizationGO:00069962660.018
catechol containing compound biosynthetic processGO:000971390.017
ras protein signal transductionGO:0007265290.017
small gtpase mediated signal transductionGO:0007264360.017
negative regulation of transportGO:00510511360.017
regulation of cellular amine metabolic processGO:003323880.017
cell type specific apoptotic processGO:00972851340.017
purine containing compound metabolic processGO:00725212530.017
single organism catabolic processGO:00447122830.017
reproductive processGO:00224143720.017
Fly
actin filament based processGO:0030029860.017
response to oxidative stressGO:00069791860.017
long chain fatty acid metabolic processGO:0001676320.017
positive regulation of peptide secretionGO:0002793520.017
cellular response to abiotic stimulusGO:0071214850.017
cellular homeostasisGO:00197252520.016
chemical homeostasisGO:00488782920.016
agingGO:00075682410.016
regulation of homeostatic processGO:00328441010.016
non canonical wnt signaling pathwayGO:003556730.016
response to woundingGO:00096112540.016
tissue morphogenesisGO:0048729220.016
limbic system developmentGO:0021761380.016
regulation of heart contractionGO:0008016480.016
cell migrationGO:00164771970.016
Fly
regulation of transcription dna templatedGO:00063553740.016
Rat Fly
developmental process involved in reproductionGO:00030061590.016
Fly
regulation of response to foodGO:0032095110.016
neuron projection morphogenesisGO:00488121220.016
regulation of ion transmembrane transportGO:00347651210.016
positive regulation of protein phosphorylationGO:00019341350.016
cellular response to growth factor stimulusGO:00713631620.016
activation of protein kinase activityGO:0032147470.015
single organism intracellular transportGO:19025821660.015
regulation of cell developmentGO:00602842630.015
nucleoside metabolic processGO:00091161790.015
positive regulation of cellular protein metabolic processGO:00322701670.015
regulation of cellular ketone metabolic processGO:0010565270.015
negative regulation of programmed cell deathGO:00430691830.015
positive regulation of blood circulationGO:1903524650.015
regulation of protein transportGO:0051223680.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
Rat Fly
positive regulation of secretion by cellGO:19035321280.015
organic acid transportGO:00158491160.015
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.015
regulation of catalytic activityGO:00507903040.015
organic cyclic compound catabolic processGO:19013611750.015
regulation of canonical wnt signaling pathwayGO:006082840.015
neuron fate commitmentGO:004866340.015
saliva secretionGO:004654130.014
response to hypoxiaGO:00016662310.014
cellular response to alcoholGO:0097306870.014
ossificationGO:0001503700.014
oxoacid metabolic processGO:00434362900.014
regulation of synaptic transmissionGO:00508041410.014
erk1 and erk2 cascadeGO:0070371480.014
kidney developmentGO:0001822670.014
regulation of anatomical structure morphogenesisGO:00226031410.014
regulation of protein kinase activityGO:00458591050.014
morphogenesis of an epitheliumGO:0002009200.014
intracellular transportGO:00469071850.014
response to inorganic substanceGO:00100353770.014
localization of cellGO:00516742020.014
Fly
response to mechanical stimulusGO:00096121340.014
single organism organelle organizationGO:19025891800.014
organic hydroxy compound transportGO:0015850770.014
positive regulation of cell differentiationGO:00455972170.014
memoryGO:0007613540.014
cellular potassium ion transportGO:0071804720.014
epithelium developmentGO:0060429960.014
Fly
epithelial cell differentiationGO:0030855710.014
Fly
ribonucleoside metabolic processGO:00091191740.014
carboxylic acid metabolic processGO:00197522890.014
regulation of establishment of protein localizationGO:0070201690.014
potassium ion transportGO:0006813970.013
endocrine system developmentGO:0035270300.013
rna metabolic processGO:00160704060.013
Rat Fly
purine ribonucleotide catabolic processGO:00091541360.013
positive regulation of serotonin secretionGO:001406410.013
protein heterooligomerizationGO:0051291890.013
negative regulation of developmental processGO:00510931250.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
protein localizationGO:00081041910.013
learning or memoryGO:0007611900.013
purine nucleoside metabolic processGO:00422781690.013
regulation of protein phosphorylationGO:00019321830.013
sodium ion transmembrane transportGO:0035725670.013
sequestering of calcium ionGO:005120880.013
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.013
positive regulation of saliva secretionGO:004687830.013
regulation of postsynaptic membrane potentialGO:0060078250.013
urinary tract smooth muscle contractionGO:001484840.013
regulation of metal ion transportGO:00109591180.013
cell morphogenesisGO:00009021420.013
lipid localizationGO:0010876620.013
glutamate secretionGO:0014047190.013
calcium ion importGO:0070509220.013
regulation of molecular functionGO:00650093980.013
sex differentiationGO:00075481130.013
Fly
monovalent inorganic cation transportGO:00156721720.012
female sex differentiationGO:0046660590.012
Fly
negative regulation of signalingGO:00230571570.012
body fluid secretionGO:0007589410.012
positive regulation of cell motilityGO:2000147970.012
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.012
negative regulation of metabolic processGO:00098923310.012
negative regulation of neuron deathGO:1901215690.012
regulation of gtpase activityGO:0043087570.012
negative regulation of amine transportGO:0051953240.012
amine metabolic processGO:0009308380.012
serotonin receptor signaling pathwayGO:0007210100.012
regulation of neuron apoptotic processGO:0043523830.012
dopamine metabolic processGO:0042417120.012
calcium ion homeostasisGO:00550741620.012
response to external biotic stimulusGO:00432072210.012
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.012
organophosphate metabolic processGO:00196373700.012
response to monosaccharideGO:00342841590.012
response to other organismGO:00517072200.012
peptide secretionGO:0002790860.012
regulation of ion homeostasisGO:2000021630.012
peptide transportGO:0015833970.012
response to glucoseGO:00097491360.012
axis specificationGO:000979840.012
negative regulation of secretionGO:0051048820.012
cytoplasmic transportGO:00164821150.012
regulation of cell projection sizeGO:003253610.012
regulation of calcium ion transportGO:0051924770.012
reactive oxygen species metabolic processGO:0072593370.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
potassium ion transmembrane transportGO:0071805710.012
immune system processGO:00023762040.012
regulation of peptide hormone secretionGO:0090276800.012
defense responseGO:00069521940.011
cellular response to estradiol stimulusGO:0071392160.011
regulation of immune system processGO:00026821230.011
negative regulation of follicle stimulating hormone secretionGO:004688230.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
camera type eye developmentGO:0043010480.011
cyclic nucleotide biosynthetic processGO:0009190630.011
response to glucocorticoidGO:00513842230.011
amine transportGO:0015837570.011
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.011
purine ribonucleotide metabolic processGO:00091502270.011
cellular response to tumor necrosis factorGO:0071356460.011
reproductionGO:00000032450.011
Fly
positive regulation of developmental processGO:00510942830.011
sequestering of metal ionGO:005123890.011
circulatory system processGO:00030131830.011
regulation of transferase activityGO:00513381230.011
single organism carbohydrate metabolic processGO:00447231180.011
ribose phosphate biosynthetic processGO:0046390870.011
positive regulation of immune system processGO:0002684900.011
positive regulation of nucleotide biosynthetic processGO:0030810360.011
protein tetramerizationGO:0051262380.011
positive regulation of action potentialGO:004576080.011
cytoskeleton organizationGO:00070101110.011
guanosine containing compound metabolic processGO:1901068740.011
male gonad developmentGO:0008584590.011
Fly
icosanoid metabolic processGO:0006690380.011
cellular response to corticosteroid stimulusGO:0071384690.011
nucleotide biosynthetic processGO:0009165980.011
muscle contractionGO:0006936880.011
eye developmentGO:0001654500.011
retina development in camera type eyeGO:0060041270.011
response to osmotic stressGO:0006970420.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.011
positive regulation of cellular amine metabolic processGO:003324030.010
appendage morphogenesisGO:003510740.010
negative regulation of cell communicationGO:00106481580.010
regulation of muscle contractionGO:0006937530.010
regulation of endocrine processGO:0044060210.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
Rat Fly
carbohydrate derivative catabolic processGO:19011361470.010
regulation of kinase activityGO:00435491170.010
transcription from rna polymerase ii promoterGO:00063662520.010
Rat Fly
positive regulation of digestive system processGO:006045680.010
positive regulation of erk1 and erk2 cascadeGO:0070374290.010
regulation of cardiac muscle contractionGO:0055117170.010
organophosphate catabolic processGO:00464341480.010
organic substance catabolic processGO:19015753160.010
anterior posterior pattern specificationGO:000995210.010

Nrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.577
Human
nervous system diseaseDOID:86300.577
Human
disease of anatomical entityDOID:700.577
Human
eye and adnexa diseaseDOID:149200.577
Human
sensory system diseaseDOID:005015500.577
Human
retinal diseaseDOID:567900.577
Human
retinal degenerationDOID:846600.334
Human
retinitis pigmentosaDOID:1058400.265
Human
night blindnessDOID:849900.103
congenital stationary night blindnessDOID:005053400.014
central nervous system diseaseDOID:33100.013