IMP: Integrative Multi-species Prediction

Rattus norvegicus

233 known processes

Rara

retinoic acid receptor, alpha

Ensembl: ENSRNOG00000009972
Entrez: 24705
RGD: 3534
UniProtKB: Q499N1

Process Predictions
Disease Predictions

Rara biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of rna metabolic process	GO:0051254	203	0.860	Human Rat
rna biosynthetic process	GO:0032774	380	0.838
cellular response to insulin stimulus	GO:0032869	81	0.827
transcription dna templated	GO:0006351	377	0.819
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.812
nucleic acid templated transcription	GO:0097659	379	0.805
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.782	Human Rat
positive regulation of rna biosynthetic process	GO:1902680	197	0.775	Human Rat
positive regulation of transcription dna templated	GO:0045893	197	0.705	Human Rat
response to peptide	GO:1901652	292	0.693
regulation of multicellular organismal development	GO:2000026	376	0.657
regulation of transcription dna templated	GO:0006355	374	0.656
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.640	Human Rat
response to peptide hormone	GO:0043434	278	0.619
regulation of nucleic acid templated transcription	GO:1903506	380	0.602
tissue development	GO:0009888	252	0.600	Rat
positive regulation of signaling	GO:0023056	270	0.565
positive regulation of cellular biosynthetic process	GO:0031328	295	0.549	Human Rat
regulation of cellular component organization	GO:0051128	368	0.526
anatomical structure morphogenesis	GO:0009653	298	0.501
regulation of rna biosynthetic process	GO:2001141	381	0.501
aging	GO:0007568	241	0.479
regulation of signal transduction	GO:0009966	318	0.475
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.474	Human Rat
negative regulation of cell differentiation	GO:0045596	99	0.459	Human
single organism reproductive process	GO:0044702	297	0.459
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.457
positive regulation of biosynthetic process	GO:0009891	319	0.457	Human Rat
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.445	Human Rat
negative regulation of cell proliferation	GO:0008285	119	0.442
negative regulation of tyrosine phosphorylation of stat5 protein	GO:0042524	1	0.434
apoptotic process	GO:0006915	381	0.433
developmental process involved in reproduction	GO:0003006	159	0.412
transcription from rna polymerase ii promoter	GO:0006366	252	0.403
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.390	Human Rat
cellular response to oxygen containing compound	GO:1901701	386	0.384	Human Rat
negative regulation of response to stimulus	GO:0048585	155	0.377
cellular response to organonitrogen compound	GO:0071417	197	0.375
rna metabolic process	GO:0016070	406	0.371
regulation of rna metabolic process	GO:0051252	391	0.363
response to insulin	GO:0032868	133	0.361
regulation of intracellular signal transduction	GO:1902531	218	0.358
response to nutrient levels	GO:0031667	370	0.353
response to monosaccharide	GO:0034284	159	0.334
programmed cell death	GO:0012501	392	0.322
mammary gland morphogenesis	GO:0060443	6	0.314
negative regulation of developmental process	GO:0051093	125	0.310	Human
renal system development	GO:0072001	67	0.308	Rat
cellular component assembly	GO:0022607	360	0.299
reproductive structure development	GO:0048608	128	0.295
positive regulation of multicellular organismal process	GO:0051240	387	0.295
tube development	GO:0035295	89	0.294	Rat
circulatory system development	GO:0072359	134	0.294
reproductive system development	GO:0061458	128	0.272
reproductive process	GO:0022414	372	0.263
cellular response to peptide hormone stimulus	GO:0071375	120	0.258
response to wounding	GO:0009611	254	0.248
microvillus assembly	GO:0030033	2	0.244
negative regulation of rna metabolic process	GO:0051253	123	0.241	Human
response to nutrient	GO:0007584	248	0.239
regulation of cell migration	GO:0030334	128	0.237
positive regulation of signal transduction	GO:0009967	175	0.234
negative regulation of biosynthetic process	GO:0009890	168	0.231
positive regulation of response to stimulus	GO:0048584	285	0.231
negative regulation of transcription dna templated	GO:0045892	116	0.230	Human
epithelium development	GO:0060429	96	0.230
gland development	GO:0048732	155	0.230
macromolecular complex subunit organization	GO:0043933	339	0.228
organ regeneration	GO:0031100	101	0.226
head development	GO:0060322	247	0.226
multi multicellular organism process	GO:0044706	138	0.225
response to carbohydrate	GO:0009743	183	0.222
positive regulation of phosphate metabolic process	GO:0045937	262	0.222
female pregnancy	GO:0007565	122	0.220
response to corticosteroid	GO:0031960	235	0.218
response to oxygen levels	GO:0070482	265	0.218
protein complex biogenesis	GO:0070271	263	0.213
negative regulation of macromolecule metabolic process	GO:0010605	260	0.207
response to oxidative stress	GO:0006979	186	0.204
negative regulation of cell development	GO:0010721	82	0.202
muscle structure development	GO:0061061	87	0.199
urogenital system development	GO:0001655	78	0.198
cellular response to peptide	GO:1901653	133	0.191
brain development	GO:0007420	247	0.190
cellular amino acid metabolic process	GO:0006520	107	0.189
regulation of catalytic activity	GO:0050790	304	0.187
response to hexose	GO:0009746	144	0.187
protein complex subunit organization	GO:0071822	302	0.185
negative regulation of metabolic process	GO:0009892	331	0.184
regulation of neuron differentiation	GO:0045664	208	0.183
regulation of nervous system development	GO:0051960	264	0.183
regeneration	GO:0031099	163	0.183
cell migration	GO:0016477	197	0.179
intracellular signal transduction	GO:0035556	314	0.178
positive regulation of cell migration	GO:0030335	96	0.175
response to cytokine	GO:0034097	215	0.173
establishment of protein localization	GO:0045184	141	0.170
positive regulation of gene expression	GO:0010628	244	0.169	Human Rat
negative regulation of protein import into nucleus translocation	GO:0033159	1	0.168
cellular response to stress	GO:0033554	269	0.168
kidney development	GO:0001822	67	0.168	Rat
cellular response to endogenous stimulus	GO:0071495	377	0.167	Human
neuron differentiation	GO:0030182	368	0.165
response to glucose	GO:0009749	136	0.164
regulation of protein import into nucleus	GO:0042306	24	0.163
retinoic acid receptor signaling pathway	GO:0048384	7	0.162
response to extracellular stimulus	GO:0009991	380	0.161
locomotion	GO:0040011	237	0.160
single organism intracellular transport	GO:1902582	166	0.160
negative regulation of cell death	GO:0060548	229	0.158
regulation of transforming growth factor beta3 production	GO:0032910	2	0.158
cellular component biogenesis	GO:0044085	368	0.158
response to inorganic substance	GO:0010035	377	0.157
regulation of cell proliferation	GO:0042127	359	0.155
localization of cell	GO:0051674	202	0.155
response to hypoxia	GO:0001666	231	0.154
negative regulation of multicellular organismal process	GO:0051241	203	0.154	Human
response to glucocorticoid	GO:0051384	223	0.152
protein import into nucleus	GO:0006606	35	0.151
organ morphogenesis	GO:0009887	75	0.151
olfactory learning	GO:0008355	1	0.147
regulation of programmed cell death	GO:0043067	341	0.146
sex differentiation	GO:0007548	113	0.145
response to retinoic acid	GO:0032526	63	0.144	Human Rat
cell type specific apoptotic process	GO:0097285	134	0.143
response to vitamin d	GO:0033280	34	0.142
heart development	GO:0007507	72	0.142
neuron development	GO:0048666	286	0.140
response to decreased oxygen levels	GO:0036293	237	0.138
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.138
intracellular receptor signaling pathway	GO:0030522	35	0.136
response to reactive oxygen species	GO:0000302	120	0.136
response to vitamin	GO:0033273	131	0.136
negative regulation of apoptotic process	GO:0043066	181	0.135
activation of jak2 kinase activity	GO:0042977	2	0.135
negative regulation of nervous system development	GO:0051961	79	0.134
organic acid metabolic process	GO:0006082	292	0.132
sensory organ development	GO:0007423	74	0.128
cation transport	GO:0006812	382	0.128
cellular response to growth factor stimulus	GO:0071363	162	0.128
response to hydrogen peroxide	GO:0042542	89	0.127
regulation of cellular component biogenesis	GO:0044087	86	0.123
epithelial cell differentiation	GO:0030855	71	0.123
negative regulation of signaling	GO:0023057	157	0.122
positive regulation of phosphorus metabolic process	GO:0010562	262	0.122
cellular response to abiotic stimulus	GO:0071214	85	0.121
neurological system process	GO:0050877	219	0.120
regulation of phosphorus metabolic process	GO:0051174	349	0.119
regulation of anatomical structure morphogenesis	GO:0022603	141	0.118
secretion	GO:0046903	307	0.116
homeostatic process	GO:0042592	331	0.114
gonad development	GO:0008406	104	0.114
regulation of apoptotic process	GO:0042981	335	0.113
biological adhesion	GO:0022610	110	0.113
hepaticobiliary system development	GO:0061008	90	0.111
hair cell differentiation	GO:0035315	2	0.111
striated muscle tissue development	GO:0014706	58	0.108
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.107	Human
skeletal system development	GO:0001501	41	0.106	Rat
response to ethanol	GO:0045471	162	0.106
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.106
regulation of response to external stimulus	GO:0032101	106	0.106
positive regulation of mitochondrion organization	GO:0010822	4	0.105
heart morphogenesis	GO:0003007	3	0.105
protein phosphorylation	GO:0006468	345	0.104	Human
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.104	Human
response to camp	GO:0051591	91	0.103
positive regulation of cellular component movement	GO:0051272	102	0.103
macromolecular complex assembly	GO:0065003	273	0.102
response to purine containing compound	GO:0014074	126	0.102
response to ionizing radiation	GO:0010212	59	0.102
regulation of cellular amine metabolic process	GO:0033238	8	0.100
liver development	GO:0001889	90	0.100
embryonic pattern specification	GO:0009880	1	0.099
negative regulation of kidney development	GO:0090185	2	0.098
regulation of cell motility	GO:2000145	131	0.097
cellular ketone metabolic process	GO:0042180	51	0.097
positive regulation of cell development	GO:0010720	176	0.097
mammary gland involution	GO:0060056	5	0.096
regulation of microvillus assembly	GO:0032534	1	0.095
regulation of metanephros development	GO:0072215	4	0.095
chemosensory behavior	GO:0007635	2	0.095
cell cell junction organization	GO:0045216	20	0.094
negative regulation of rna biosynthetic process	GO:1902679	118	0.094	Human
mesenchymal to epithelial transition	GO:0060231	3	0.094
negative regulation of neurogenesis	GO:0050768	78	0.094
cellular response to nitrogen compound	GO:1901699	210	0.094
sulfur compound metabolic process	GO:0006790	70	0.093
ribonucleoside metabolic process	GO:0009119	174	0.092
protein complex assembly	GO:0006461	263	0.092
oxoacid metabolic process	GO:0043436	290	0.091
single organism nuclear import	GO:1902593	35	0.091
regulation of nucleocytoplasmic transport	GO:0046822	28	0.091
single organism behavior	GO:0044708	130	0.091
carboxylic acid metabolic process	GO:0019752	289	0.089
ribose phosphate metabolic process	GO:0019693	235	0.088
eye morphogenesis	GO:0048592	4	0.088
cell morphogenesis involved in differentiation	GO:0000904	119	0.088
muscle cell proliferation	GO:0033002	84	0.087
peptidyl tyrosine phosphorylation	GO:0018108	72	0.087
multi organism reproductive process	GO:0044703	262	0.087
regulation of cell development	GO:0060284	263	0.087
positive regulation of molecular function	GO:0044093	230	0.086	Human
cell motility	GO:0048870	202	0.084
response to estradiol	GO:0032355	164	0.083
positive regulation of cellular protein metabolic process	GO:0032270	167	0.083
neuron projection development	GO:0031175	273	0.083
response to acid chemical	GO:0001101	222	0.083	Human Rat
positive regulation of catalytic activity	GO:0043085	184	0.083
negative regulation of cell communication	GO:0010648	158	0.082
cardiac muscle tissue growth	GO:0055017	20	0.082
cell cell signaling	GO:0007267	335	0.081
regulation of smooth muscle cell proliferation	GO:0048660	75	0.081
cellular response to hormone stimulus	GO:0032870	247	0.081	Human
negative regulation of gene expression	GO:0010629	199	0.080
organelle organization	GO:0006996	266	0.080
circulatory system process	GO:0003013	183	0.080
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.080
cardiovascular system development	GO:0072358	134	0.079
nitrogen compound transport	GO:0071705	229	0.079
negative regulation of transport	GO:0051051	136	0.079
positive regulation of cell communication	GO:0010647	271	0.079
camera type eye development	GO:0043010	48	0.078
regulation of neurogenesis	GO:0050767	247	0.078
regulation of protein targeting	GO:1903533	28	0.078
regulation of apoptotic signaling pathway	GO:2001233	13	0.077
regulation of activation of jak2 kinase activity	GO:0010534	1	0.077
transmission of nerve impulse	GO:0019226	42	0.076
regulation of response to stress	GO:0080134	126	0.076
g protein coupled receptor signaling pathway	GO:0007186	242	0.075
response to biotic stimulus	GO:0009607	226	0.075
amine metabolic process	GO:0009308	38	0.075
vasculature development	GO:0001944	70	0.075
positive regulation of nervous system development	GO:0051962	178	0.075
jak stat cascade	GO:0007259	26	0.075
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.074	Human
positive regulation of intracellular signal transduction	GO:1902533	138	0.074
cellular lipid metabolic process	GO:0044255	208	0.073
negative regulation of cardiac muscle tissue development	GO:0055026	3	0.073
forebrain development	GO:0030900	98	0.073
transforming growth factor beta receptor signaling pathway	GO:0007179	18	0.073
purine containing compound metabolic process	GO:0072521	253	0.072
regulation of cellular amino acid metabolic process	GO:0006521	2	0.072
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	5	0.071
endocrine system development	GO:0035270	30	0.071	Rat
central nervous system development	GO:0007417	311	0.071
nuclear import	GO:0051170	35	0.070
female sex differentiation	GO:0046660	59	0.070
embryo development	GO:0009790	49	0.070	Rat
muscle tissue development	GO:0060537	58	0.070
neuron projection morphogenesis	GO:0048812	122	0.070
negative regulation of programmed cell death	GO:0043069	183	0.069
myelination	GO:0042552	39	0.069
regulation of activation of janus kinase activity	GO:0010533	1	0.069
gland morphogenesis	GO:0022612	12	0.069
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	3	0.069
regulation of cellular component movement	GO:0051270	150	0.069
monovalent inorganic cation transport	GO:0015672	172	0.068
regulation of protein metabolic process	GO:0051246	289	0.068
response to estrogen	GO:0043627	232	0.068
blood vessel development	GO:0001568	69	0.067
regulation of transferase activity	GO:0051338	123	0.066
response to growth factor	GO:0070848	189	0.066
cellular component movement	GO:0006928	248	0.065
axon ensheathment	GO:0008366	40	0.065
establishment of protein localization to organelle	GO:0072594	44	0.065
regulation of epithelial cell differentiation	GO:0030856	12	0.064
negative regulation of signal transduction	GO:0009968	83	0.064
regulation of phosphate metabolic process	GO:0019220	349	0.064
cellular protein localization	GO:0034613	122	0.063
negative regulation of cellular metabolic process	GO:0031324	281	0.063
positive regulation of neurogenesis	GO:0050769	165	0.063
mechanoreceptor differentiation	GO:0042490	2	0.062
regulation of locomotion	GO:0040012	148	0.062
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.061
action potential	GO:0001508	54	0.061
protein import	GO:0017038	37	0.060
nuclear transport	GO:0051169	49	0.060
immune system development	GO:0002520	41	0.060	Human
negative regulation of activation of jak2 kinase activity	GO:1902569	1	0.060
regulation of jak stat cascade	GO:0046425	21	0.060
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:0097296	1	0.059
intracellular transport	GO:0046907	185	0.059
insulin receptor signaling pathway	GO:0008286	24	0.059
protein targeting to nucleus	GO:0044744	35	0.059
regulation of behavior	GO:0050795	61	0.059
cardiac ventricle development	GO:0003231	1	0.058
positive regulation of developmental process	GO:0051094	283	0.058
regulation of purine nucleotide metabolic process	GO:1900542	115	0.058
purine ribonucleotide metabolic process	GO:0009150	227	0.058
positive regulation of protein phosphorylation	GO:0001934	135	0.058
cellular amine metabolic process	GO:0044106	38	0.057
male sex differentiation	GO:0046661	64	0.056
carbohydrate derivative catabolic process	GO:1901136	147	0.055
response to organophosphorus	GO:0046683	102	0.055
positive regulation of cell motility	GO:2000147	97	0.054
striated muscle cell proliferation	GO:0014855	9	0.054
axis specification	GO:0009798	4	0.054
regulation of organelle organization	GO:0033043	80	0.054
purine nucleoside metabolic process	GO:0042278	169	0.053
organ formation	GO:0048645	3	0.053
positive regulation of protein metabolic process	GO:0051247	178	0.053
bmp signaling pathway	GO:0030509	4	0.052
organophosphate metabolic process	GO:0019637	370	0.052
vesicle mediated transport	GO:0016192	181	0.052	Human
sexual reproduction	GO:0019953	148	0.052
regulation of vasculature development	GO:1901342	44	0.052
regulation of cellular protein metabolic process	GO:0032268	267	0.052
positive regulation of mesenchymal cell proliferation	GO:0002053	4	0.052
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.052
placenta development	GO:0001890	22	0.052
positive regulation of kinase activity	GO:0033674	77	0.051
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.051
organonitrogen compound catabolic process	GO:1901565	179	0.051
cellular component morphogenesis	GO:0032989	155	0.051
regulation of neuron projection development	GO:0010975	161	0.051
response to temperature stimulus	GO:0009266	94	0.051
cell adhesion	GO:0007155	110	0.051
single organism cellular localization	GO:1902580	102	0.050
positive regulation of nucleotide metabolic process	GO:0045981	91	0.050
signal transduction by phosphorylation	GO:0023014	144	0.050
cellular response to transforming growth factor beta stimulus	GO:0071560	41	0.050
regulation of protein transport	GO:0051223	68	0.050
peptidyl amino acid modification	GO:0018193	126	0.050
cellular response to lipid	GO:0071396	201	0.050	Human Rat
smooth muscle cell proliferation	GO:0048659	77	0.049
reactive oxygen species metabolic process	GO:0072593	37	0.049
cellular response to external stimulus	GO:0071496	118	0.048
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.048
cardiac chamber development	GO:0003205	1	0.048
hexose metabolic process	GO:0019318	58	0.048
ribonucleotide catabolic process	GO:0009261	136	0.048
response to transforming growth factor beta	GO:0071559	46	0.048
stem cell maintenance	GO:0019827	6	0.048
development of primary sexual characteristics	GO:0045137	107	0.047
regulation of establishment of protein localization	GO:0070201	69	0.047
neuron death	GO:0070997	127	0.047
cognition	GO:0050890	92	0.047
regulation of growth	GO:0040008	105	0.047
cellular response to mechanical stimulus	GO:0071260	48	0.047
mapk cascade	GO:0000165	140	0.046
positive regulation of biomineral tissue development	GO:0070169	4	0.046
regulation of cellular ketone metabolic process	GO:0010565	27	0.046
regulation of cellular localization	GO:0060341	263	0.046
cell projection morphogenesis	GO:0048858	123	0.046
response to bacterium	GO:0009617	200	0.046
response to other organism	GO:0051707	220	0.045
response to amino acid	GO:0043200	75	0.045
mammary gland development	GO:0030879	38	0.045
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.045
response to radiation	GO:0009314	137	0.045
nucleotide metabolic process	GO:0009117	279	0.045
regulation of phosphorylation	GO:0042325	248	0.045
mammary gland epithelium development	GO:0061180	1	0.045
cell projection organization	GO:0030030	302	0.045
negative regulation of metanephros development	GO:0072217	2	0.045
positive regulation of release of cytochrome c from mitochondria	GO:0090200	3	0.045
single organism organelle organization	GO:1902589	180	0.045
protein localization to nucleus	GO:0034504	39	0.044
regulation of peptide secretion	GO:0002791	82	0.044
behavior	GO:0007610	205	0.044
cellular response to organic cyclic compound	GO:0071407	202	0.044	Human
regulation of cellular catabolic process	GO:0031329	101	0.044
negative regulation of heart growth	GO:0061117	3	0.043
smad protein complex assembly	GO:0007183	1	0.043
multicellular organismal reproductive process	GO:0048609	233	0.043
peptide transport	GO:0015833	97	0.043
glycoside transport	GO:1901656	2	0.043
carbohydrate derivative metabolic process	GO:1901135	346	0.043
response to molecule of bacterial origin	GO:0002237	194	0.043
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.042
protein localization	GO:0008104	191	0.042
protein localization to organelle	GO:0033365	57	0.041
positive regulation of cellular amine metabolic process	GO:0033240	3	0.041
cytoskeleton organization	GO:0007010	111	0.040
response to mechanical stimulus	GO:0009612	134	0.040
positive regulation of hepatocyte differentiation	GO:0070368	2	0.040
regulation of microvillus organization	GO:0032530	1	0.040
response to external biotic stimulus	GO:0043207	221	0.040
cell differentiation involved in kidney development	GO:0061005	4	0.040
ovulation cycle process	GO:0022602	50	0.039
outer mitochondrial membrane organization	GO:0007008	1	0.039
negative regulation of cytokine production	GO:0001818	16	0.039	Human
mesenchymal cell proliferation	GO:0010463	4	0.039
regulation of neuron death	GO:1901214	115	0.038
regulation of carbohydrate metabolic process	GO:0006109	41	0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	10	0.038
protein transport	GO:0015031	132	0.038
regulation of cell differentiation	GO:0045595	320	0.038
positive regulation of focal adhesion assembly	GO:0051894	2	0.038
negative regulation of neuron death	GO:1901215	69	0.038
cell fate commitment involved in pattern specification	GO:0060581	2	0.038
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.038
cellular macromolecular complex assembly	GO:0034622	58	0.038
positive regulation of neuron migration	GO:2001224	2	0.037
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	5	0.037
regulation of kinase activity	GO:0043549	117	0.037
small gtpase mediated signal transduction	GO:0007264	36	0.037
protein targeting	GO:0006605	61	0.037
hematopoietic or lymphoid organ development	GO:0048534	36	0.036	Human
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	27	0.036
glycosyl compound catabolic process	GO:1901658	126	0.036
positive regulation of bone mineralization	GO:0030501	4	0.036
nucleoside metabolic process	GO:0009116	179	0.036
negative regulation of cellular biosynthetic process	GO:0031327	161	0.036
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.036
regulation of molecular function	GO:0065009	398	0.036
eye development	GO:0001654	50	0.036
regulation of synaptic plasticity	GO:0048167	70	0.036
kidney epithelium development	GO:0072073	19	0.035
positive regulation of gtpase activity	GO:0043547	47	0.035
organophosphate biosynthetic process	GO:0090407	143	0.035
regulation of system process	GO:0044057	208	0.035
axon development	GO:0061564	96	0.035
heterotypic cell cell adhesion	GO:0034113	2	0.035
response to metformin	GO:1901558	1	0.035
digestive system development	GO:0055123	41	0.034	Rat
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.034
response to lipopolysaccharide	GO:0032496	191	0.034
male gonad development	GO:0008584	59	0.034
somatic stem cell maintenance	GO:0035019	2	0.034
defense response	GO:0006952	194	0.034
regulation of homeostatic process	GO:0032844	101	0.033
single organism catabolic process	GO:0044712	283	0.033
protein oligomerization	GO:0051259	191	0.033
organic substance catabolic process	GO:1901575	316	0.033
regulation of nucleoside metabolic process	GO:0009118	66	0.033
regulation of peptide transport	GO:0090087	87	0.033
inner ear receptor cell differentiation	GO:0060113	2	0.033
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0003339	2	0.033
ras protein signal transduction	GO:0007265	29	0.032
secretion by cell	GO:0032940	248	0.032
gamete generation	GO:0007276	124	0.032
rhythmic process	GO:0048511	156	0.032	Rat
reproduction	GO:0000003	245	0.032
angiogenesis	GO:0001525	53	0.031
nucleoside triphosphate catabolic process	GO:0009143	123	0.031
organophosphate catabolic process	GO:0046434	148	0.031
response to ammonium ion	GO:0060359	71	0.031
apoptotic signaling pathway	GO:0097190	27	0.031
regulation of satellite cell proliferation	GO:0014842	1	0.031
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.031
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.031
glial cell apoptotic process	GO:0034349	8	0.031
epithelial cell differentiation involved in kidney development	GO:0035850	3	0.031
nucleobase containing small molecule metabolic process	GO:0055086	316	0.031
metanephric renal vesicle morphogenesis	GO:0072283	3	0.031
cytoplasmic transport	GO:0016482	115	0.031
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0003340	2	0.031
regulation of stem cell differentiation	GO:2000736	2	0.031
organ growth	GO:0035265	24	0.030
olfactory behavior	GO:0042048	2	0.030
cartilage development	GO:0051216	22	0.030	Rat
regulation of nucleotide metabolic process	GO:0006140	117	0.030
response to ketone	GO:1901654	182	0.030
negative regulation of cell cycle g1 s phase transition	GO:1902807	2	0.030
regulation of cell projection organization	GO:0031344	175	0.030
immune system process	GO:0002376	204	0.030	Human
lipid storage	GO:0019915	1	0.030
single organism carbohydrate metabolic process	GO:0044723	118	0.029
t cell differentiation	GO:0030217	9	0.029	Human
positive regulation of cellular component biogenesis	GO:0044089	55	0.029
cellular macromolecule localization	GO:0070727	122	0.029
blood circulation	GO:0008015	183	0.029
negative regulation of phosphate metabolic process	GO:0045936	80	0.029
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.029
regulation of cell cycle g1 s phase transition	GO:1902806	7	0.029
mitotic cell cycle	GO:0000278	49	0.029
negative regulation of intracellular signal transduction	GO:1902532	38	0.029
nucleocytoplasmic transport	GO:0006913	48	0.029
positive regulation of nucleoside metabolic process	GO:0045979	55	0.029
positive regulation of cell death	GO:0010942	184	0.029
muscle organ development	GO:0007517	50	0.029
purine ribonucleoside metabolic process	GO:0046128	168	0.029
ion homeostasis	GO:0050801	212	0.029
glycosyl compound metabolic process	GO:1901657	182	0.029
reactive oxygen species biosynthetic process	GO:1903409	8	0.029
positive regulation of transforming growth factor beta3 production	GO:0032916	2	0.029
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.028
regulation of gluconeogenesis	GO:0006111	4	0.028
regulation of cell adhesion	GO:0030155	52	0.028
response to heat	GO:0009408	60	0.028
tissue remodeling	GO:0048771	40	0.028
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	28	0.028
blood vessel morphogenesis	GO:0048514	58	0.028
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.028
response to interleukin 1	GO:0070555	55	0.028
positive regulation of jak stat cascade	GO:0046427	19	0.028
potassium ion transport	GO:0006813	97	0.027
male germ line stem cell asymmetric division	GO:0048133	1	0.027
erythrocyte differentiation	GO:0030218	1	0.027
monosaccharide metabolic process	GO:0005996	61	0.027

Rara disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.066
gastrointestinal system disease	DOID:77	0.066
disease of metabolism	DOID:0014667	0.028

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