IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Kcnv2

potassium channel, subfamily V, member 2

Ensembl: ENSRNOG00000012566
Entrez: 294065
RGD: 1309271
UniProtKB: D3ZZR6

Process Predictions
Disease Predictions

Kcnv2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of intracellular signal transduction	GO:1902531	218	0.263
cation transport	GO:0006812	382	0.184	Rat
transmembrane transport	GO:0055085	412	0.166	Rat
cation transmembrane transport	GO:0098655	263	0.166	Rat
single organism biosynthetic process	GO:0044711	342	0.162
blood circulation	GO:0008015	183	0.144
positive regulation of multicellular organismal process	GO:0051240	387	0.143
homeostatic process	GO:0042592	331	0.137	Rat
cellular ion homeostasis	GO:0006873	184	0.132	Rat
regulation of signal transduction	GO:0009966	318	0.126
macromolecular complex assembly	GO:0065003	273	0.123	Rat
rhythmic process	GO:0048511	156	0.122
growth	GO:0040007	165	0.112
metal ion transport	GO:0030001	289	0.108	Rat
positive regulation of biosynthetic process	GO:0009891	319	0.107
multicellular organismal reproductive process	GO:0048609	233	0.106
circulatory system process	GO:0003013	183	0.099
regulation of cell proliferation	GO:0042127	359	0.091	Rat
neuron differentiation	GO:0030182	368	0.087
regulation of growth	GO:0040008	105	0.082
response to corticosteroid	GO:0031960	235	0.082
inorganic ion transmembrane transport	GO:0098660	229	0.080	Rat
positive regulation of cellular biosynthetic process	GO:0031328	295	0.079
ion homeostasis	GO:0050801	212	0.079	Rat
positive regulation of cell proliferation	GO:0008284	249	0.077	Rat
reproductive process	GO:0022414	372	0.076
regulation of blood circulation	GO:1903522	110	0.075
regulation of molecular function	GO:0065009	398	0.073
positive regulation of signal transduction	GO:0009967	175	0.072
neuron development	GO:0048666	286	0.071
divalent inorganic cation homeostasis	GO:0072507	165	0.071	Rat
cellular component assembly	GO:0022607	360	0.070	Rat
cellular metal ion homeostasis	GO:0006875	172	0.068	Rat
single organism reproductive process	GO:0044702	297	0.067
reproduction	GO:0000003	245	0.066
cellular response to endogenous stimulus	GO:0071495	377	0.065	Rat
programmed cell death	GO:0012501	392	0.064
response to oxygen levels	GO:0070482	265	0.063	Rat
regulation of multicellular organismal development	GO:2000026	376	0.062
heart development	GO:0007507	72	0.061
positive regulation of transport	GO:0051050	245	0.061
positive regulation of cell communication	GO:0010647	271	0.061
regulation of ion transport	GO:0043269	245	0.060	Rat
positive regulation of signaling	GO:0023056	270	0.060
regulation of tube size	GO:0035150	89	0.058
multicellular organism reproduction	GO:0032504	233	0.058
neurological system process	GO:0050877	219	0.056
lipid metabolic process	GO:0006629	283	0.056
g protein coupled receptor signaling pathway	GO:0007186	242	0.056
cellular component biogenesis	GO:0044085	368	0.054	Rat
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.053	Rat
cellular chemical homeostasis	GO:0055082	247	0.053	Rat
regulation of cellular localization	GO:0060341	263	0.052
cation homeostasis	GO:0055080	195	0.052	Rat
behavior	GO:0007610	205	0.050
response to molecule of bacterial origin	GO:0002237	194	0.050
steroid metabolic process	GO:0008202	73	0.049
regulation of phosphorus metabolic process	GO:0051174	349	0.049
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.048
calcium ion homeostasis	GO:0055074	162	0.047	Rat
cellular calcium ion homeostasis	GO:0006874	160	0.047	Rat
tissue development	GO:0009888	252	0.047
protein complex assembly	GO:0006461	263	0.046	Rat
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.046
protein complex subunit organization	GO:0071822	302	0.045	Rat
positive regulation of blood circulation	GO:1903524	65	0.045
peptidyl tyrosine phosphorylation	GO:0018108	72	0.044
positive regulation of phosphate metabolic process	GO:0045937	262	0.043
positive regulation of cell differentiation	GO:0045597	217	0.043
regulation of hormone levels	GO:0010817	187	0.043
developmental process involved in reproduction	GO:0003006	159	0.042
inorganic cation transmembrane transport	GO:0098662	202	0.042	Rat
feeding behavior	GO:0007631	53	0.041
positive regulation of phosphorus metabolic process	GO:0010562	262	0.040
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.039
secretion by cell	GO:0032940	248	0.039
chemical homeostasis	GO:0048878	292	0.039	Rat
positive regulation of intracellular signal transduction	GO:1902533	138	0.039
cellular response to stress	GO:0033554	269	0.039
reproductive structure development	GO:0048608	128	0.039
regulation of system process	GO:0044057	208	0.039
multi organism reproductive process	GO:0044703	262	0.038
calcium ion transport	GO:0006816	131	0.038
organic hydroxy compound metabolic process	GO:1901615	115	0.038
apoptotic process	GO:0006915	381	0.037
regulation of programmed cell death	GO:0043067	341	0.037
response to peptide hormone	GO:0043434	278	0.037
positive regulation of response to stimulus	GO:0048584	285	0.036
positive regulation of ion transport	GO:0043270	94	0.036
regulation of anatomical structure size	GO:0090066	135	0.036
negative regulation of macromolecule metabolic process	GO:0010605	260	0.036
steroid biosynthetic process	GO:0006694	48	0.036
catabolic process	GO:0009056	351	0.036
response to peptide	GO:1901652	292	0.035
regulation of cellular protein metabolic process	GO:0032268	267	0.035
regulation of apoptotic process	GO:0042981	335	0.035
cellular homeostasis	GO:0019725	252	0.035	Rat
negative regulation of molecular function	GO:0044092	133	0.035
response to extracellular stimulus	GO:0009991	380	0.035
anatomical structure morphogenesis	GO:0009653	298	0.035
nucleotide metabolic process	GO:0009117	279	0.035
positive regulation of gene expression	GO:0010628	244	0.034
multi multicellular organism process	GO:0044706	138	0.034
regulation of catalytic activity	GO:0050790	304	0.034
regulation of nervous system development	GO:0051960	264	0.034
protein complex biogenesis	GO:0070271	263	0.034	Rat
ovulation cycle	GO:0042698	67	0.034
response to cytokine	GO:0034097	215	0.034
cell cycle	GO:0007049	101	0.034	Rat
negative regulation of cellular metabolic process	GO:0031324	281	0.034
protein phosphorylation	GO:0006468	345	0.033
eye morphogenesis	GO:0048592	4	0.033
carbohydrate derivative metabolic process	GO:1901135	346	0.033
ion transmembrane transport	GO:0034220	365	0.032	Rat
sensory organ development	GO:0007423	74	0.032
axonogenesis	GO:0007409	71	0.031
regulation of cell differentiation	GO:0045595	320	0.031
regulation of phosphorylation	GO:0042325	248	0.031
macromolecular complex subunit organization	GO:0043933	339	0.031	Rat
response to ketone	GO:1901654	182	0.030
cellular response to hormone stimulus	GO:0032870	247	0.030
secretion	GO:0046903	307	0.030
positive regulation of cellular protein metabolic process	GO:0032270	167	0.030
cellular amine metabolic process	GO:0044106	38	0.029
response to decreased oxygen levels	GO:0036293	237	0.029	Rat
hormone metabolic process	GO:0042445	69	0.029
divalent inorganic cation transport	GO:0072511	134	0.029
intracellular signal transduction	GO:0035556	314	0.029
nucleoside phosphate metabolic process	GO:0006753	283	0.029
chemotaxis	GO:0006935	66	0.029
central nervous system development	GO:0007417	311	0.029
positive regulation of cell death	GO:0010942	184	0.029
brain development	GO:0007420	247	0.029
regulation of protein metabolic process	GO:0051246	289	0.028
regulation of lipid biosynthetic process	GO:0046890	38	0.028
lipid biosynthetic process	GO:0008610	128	0.028
organ morphogenesis	GO:0009887	75	0.028
positive regulation of protein kinase activity	GO:0045860	73	0.028
regulation of phosphate metabolic process	GO:0019220	349	0.028
regulation of cellular component organization	GO:0051128	368	0.028
peptidyl tyrosine modification	GO:0018212	72	0.028
organic hydroxy compound transport	GO:0015850	77	0.027
response to estradiol	GO:0032355	164	0.027
axon development	GO:0061564	96	0.027
regulation of blood pressure	GO:0008217	83	0.026
cellular response to oxygen containing compound	GO:1901701	386	0.026
monoamine transport	GO:0015844	43	0.026
cell projection organization	GO:0030030	302	0.026
regulation of rna biosynthetic process	GO:2001141	381	0.026
rna biosynthetic process	GO:0032774	380	0.025
positive regulation of lipid biosynthetic process	GO:0046889	25	0.025
muscle system process	GO:0003012	115	0.025
response to lipopolysaccharide	GO:0032496	191	0.025
ribose phosphate metabolic process	GO:0019693	235	0.025
response to bacterium	GO:0009617	200	0.025
organelle organization	GO:0006996	266	0.025
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.025
ribonucleotide metabolic process	GO:0009259	231	0.025
cellular cation homeostasis	GO:0030003	180	0.025	Rat
aging	GO:0007568	241	0.025
sodium ion transport	GO:0006814	82	0.024
negative regulation of metabolic process	GO:0009892	331	0.024
regulation of cell development	GO:0060284	263	0.024
nucleobase containing small molecule metabolic process	GO:0055086	316	0.024
positive regulation of cell development	GO:0010720	176	0.024
circadian rhythm	GO:0007623	88	0.024
cell growth	GO:0016049	104	0.024
response to ethanol	GO:0045471	162	0.023
positive regulation of growth	GO:0045927	55	0.023
response to nutrient levels	GO:0031667	370	0.023
positive regulation of transcription dna templated	GO:0045893	197	0.023
response to anoxia	GO:0034059	4	0.023
negative regulation of cell death	GO:0060548	229	0.023
tube development	GO:0035295	89	0.022
rna metabolic process	GO:0016070	406	0.022
regulation of cellular amine metabolic process	GO:0033238	8	0.022
response to wounding	GO:0009611	254	0.022
regulation of protein phosphorylation	GO:0001932	183	0.022
response to biotic stimulus	GO:0009607	226	0.022
organic substance catabolic process	GO:1901575	316	0.021
cellular ketone metabolic process	GO:0042180	51	0.021
oxidation reduction process	GO:0055114	304	0.021
small gtpase mediated signal transduction	GO:0007264	36	0.021
cellular component morphogenesis	GO:0032989	155	0.021
regulation of membrane potential	GO:0042391	110	0.021	Rat
synaptic transmission	GO:0007268	235	0.021
gonad development	GO:0008406	104	0.021
regulation of blood vessel size	GO:0050880	89	0.021
nitrogen compound transport	GO:0071705	229	0.021
anion transport	GO:0006820	178	0.020
anterior posterior pattern specification	GO:0009952	1	0.020
response to vitamin	GO:0033273	131	0.020
regulation of body fluid levels	GO:0050878	90	0.020
neuron projection development	GO:0031175	273	0.020
cellular amino acid metabolic process	GO:0006520	107	0.020
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.020
response to acid chemical	GO:0001101	222	0.020
cell cell signaling	GO:0007267	335	0.020
regulation of anatomical structure morphogenesis	GO:0022603	141	0.020
positive regulation of protein metabolic process	GO:0051247	178	0.020
proteolysis	GO:0006508	175	0.020
regulation of neurogenesis	GO:0050767	247	0.020
positive regulation of mapk cascade	GO:0043410	92	0.019
regulation of secretion	GO:0051046	224	0.019
cardiovascular system development	GO:0072358	134	0.019
response to alkaloid	GO:0043279	132	0.019
negative regulation of gene expression	GO:0010629	199	0.019
purine containing compound metabolic process	GO:0072521	253	0.019
hormone biosynthetic process	GO:0042446	25	0.019
sensory perception	GO:0007600	101	0.019
potassium ion transmembrane transport	GO:0071805	71	0.019	Rat
positive regulation of neurogenesis	GO:0050769	165	0.019
head development	GO:0060322	247	0.018
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.018
muscle tissue development	GO:0060537	58	0.018
cellular catabolic process	GO:0044248	295	0.018
positive regulation of phosphorylation	GO:0042327	177	0.018
single organism behavior	GO:0044708	130	0.018
purine nucleotide metabolic process	GO:0006163	229	0.018
regulation of protein modification process	GO:0031399	194	0.018
regulation of cellular ketone metabolic process	GO:0010565	27	0.018
protein heterooligomerization	GO:0051291	89	0.018	Rat
protein oligomerization	GO:0051259	191	0.018	Rat
muscle organ development	GO:0007517	50	0.018
activation of protein kinase activity	GO:0032147	47	0.018
regulation of epithelial cell proliferation	GO:0050678	49	0.018
regulation of erk1 and erk2 cascade	GO:0070372	41	0.017
macromolecule localization	GO:0033036	252	0.017
cell cycle process	GO:0022402	57	0.017	Rat
isoprenoid metabolic process	GO:0006720	45	0.017
lung development	GO:0030324	43	0.017
regulation of nucleic acid templated transcription	GO:1903506	380	0.017
response to histamine	GO:0034776	3	0.017
positive regulation of rna metabolic process	GO:0051254	203	0.017
response to insulin	GO:0032868	133	0.017
developmental growth	GO:0048589	100	0.017
regulation of metal ion transport	GO:0010959	118	0.017
mitotic cell cycle process	GO:1903047	35	0.016	Rat
regulation of muscle contraction	GO:0006937	53	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.016
regulation of nucleotide metabolic process	GO:0006140	117	0.016
positive regulation of developmental process	GO:0051094	283	0.016
transcription from rna polymerase ii promoter	GO:0006366	252	0.016
response to glucocorticoid	GO:0051384	223	0.016
cofactor metabolic process	GO:0051186	95	0.016
purine ribonucleotide metabolic process	GO:0009150	227	0.016
muscle structure development	GO:0061061	87	0.016
response to nutrient	GO:0007584	248	0.016
oxoacid metabolic process	GO:0043436	290	0.016
response to radiation	GO:0009314	137	0.015
amine metabolic process	GO:0009308	38	0.015
regulation of response to stress	GO:0080134	126	0.015
reproductive system development	GO:0061458	128	0.015
positive regulation of kinase activity	GO:0033674	77	0.015
vascular process in circulatory system	GO:0003018	96	0.015
response to glucose	GO:0009749	136	0.015
cell type specific apoptotic process	GO:0097285	134	0.015
regulation of cellular catabolic process	GO:0031329	101	0.015
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.015
cellular response to growth factor stimulus	GO:0071363	162	0.015	Rat
locomotion	GO:0040011	237	0.015
regulation of secretion by cell	GO:1903530	208	0.015
sex differentiation	GO:0007548	113	0.015
cellular lipid metabolic process	GO:0044255	208	0.015
regulation of transferase activity	GO:0051338	123	0.015
positive regulation of secretion by cell	GO:1903532	128	0.015
circulatory system development	GO:0072359	134	0.015
axis specification	GO:0009798	4	0.015
gamete generation	GO:0007276	124	0.015
response to hypoxia	GO:0001666	231	0.015	Rat
single organism intracellular transport	GO:1902582	166	0.014
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
non canonical wnt signaling pathway	GO:0035567	3	0.014
purine ribonucleoside metabolic process	GO:0046128	168	0.014
regulation of rna metabolic process	GO:0051252	391	0.014
epithelial cell proliferation	GO:0050673	54	0.014
response to temperature stimulus	GO:0009266	94	0.014
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.014
sexual reproduction	GO:0019953	148	0.014
cell morphogenesis	GO:0000902	142	0.014
neuropeptide signaling pathway	GO:0007218	29	0.014
organophosphate metabolic process	GO:0019637	370	0.014
vasoconstriction	GO:0042310	54	0.014
nucleic acid templated transcription	GO:0097659	379	0.014
heart process	GO:0003015	57	0.014
nucleoside metabolic process	GO:0009116	179	0.014
protein import into nucleus	GO:0006606	35	0.014
regulation of transcription dna templated	GO:0006355	374	0.014
cellular component movement	GO:0006928	248	0.014
female gonad development	GO:0008585	53	0.014
divalent metal ion transport	GO:0070838	132	0.013
response to hexose	GO:0009746	144	0.013
negative regulation of cell communication	GO:0010648	158	0.013
negative regulation of programmed cell death	GO:0043069	183	0.013
respiratory tube development	GO:0030323	43	0.013
behavioral response to nicotine	GO:0035095	2	0.013
epithelium development	GO:0060429	96	0.013
camp biosynthetic process	GO:0006171	47	0.013
male sex differentiation	GO:0046661	64	0.013
ras protein signal transduction	GO:0007265	29	0.013
spermatogenesis	GO:0007283	99	0.013
renal system process	GO:0003014	40	0.013
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.013
heart morphogenesis	GO:0003007	3	0.013
organonitrogen compound biosynthetic process	GO:1901566	167	0.013
regulation of cellular amino acid metabolic process	GO:0006521	2	0.013
response to inorganic substance	GO:0010035	377	0.013	Rat
negative regulation of multicellular organismal process	GO:0051241	203	0.013
development of primary sexual characteristics	GO:0045137	107	0.013
positive regulation of nervous system development	GO:0051962	178	0.013
epithelial cell differentiation	GO:0030855	71	0.012
embryo development	GO:0009790	49	0.012
transmission of nerve impulse	GO:0019226	42	0.012
amine transport	GO:0015837	57	0.012
cytosolic calcium ion homeostasis	GO:0051480	140	0.012	Rat
neuronal action potential	GO:0019228	35	0.012
regulation of hydrolase activity	GO:0051336	143	0.012
mitotic cell cycle	GO:0000278	49	0.012	Rat
positive regulation of protein modification process	GO:0031401	142	0.012
regulation of developmental growth	GO:0048638	45	0.012
metal ion homeostasis	GO:0055065	186	0.012	Rat
carboxylic acid metabolic process	GO:0019752	289	0.012
female sex differentiation	GO:0046660	59	0.012
carbohydrate derivative biosynthetic process	GO:1901137	124	0.012
positive regulation of catalytic activity	GO:0043085	184	0.012
regulation of response to external stimulus	GO:0032101	106	0.012
aromatic compound catabolic process	GO:0019439	168	0.012
organic cyclic compound catabolic process	GO:1901361	175	0.012
organonitrogen compound catabolic process	GO:1901565	179	0.012
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.012
striated muscle contraction	GO:0006941	44	0.012
regeneration	GO:0031099	163	0.012
positive regulation of epithelial cell proliferation	GO:0050679	32	0.012
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
transformation of host cell by virus	GO:0019087	4	0.012
regulation of mapk cascade	GO:0043408	116	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.011
single organism cellular localization	GO:1902580	102	0.011
positive regulation of secretion	GO:0051047	140	0.011
response to external biotic stimulus	GO:0043207	221	0.011
male gamete generation	GO:0048232	99	0.011
cellular response to organonitrogen compound	GO:0071417	197	0.011
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.011
positive regulation of peptide hormone secretion	GO:0090277	50	0.011
cellular potassium ion transport	GO:0071804	72	0.011	Rat
response to progesterone	GO:0032570	48	0.011
muscle cell differentiation	GO:0042692	52	0.011
negative regulation of neuron death	GO:1901215	69	0.011
carboxylic acid transport	GO:0046942	115	0.011
response to estrogen	GO:0043627	232	0.011
positive regulation of nucleotide metabolic process	GO:0045981	91	0.011
activation of janus kinase activity	GO:0042976	5	0.011
negative regulation of cell proliferation	GO:0008285	119	0.011
negative regulation of apoptotic process	GO:0043066	181	0.011
saliva secretion	GO:0046541	3	0.011
regulation of muscle organ development	GO:0048634	26	0.011
catecholamine transport	GO:0051937	37	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
development of primary female sexual characteristics	GO:0046545	56	0.011
negative regulation of transport	GO:0051051	136	0.011
eye development	GO:0001654	50	0.011
cellular response to acid chemical	GO:0071229	75	0.011
positive regulation of molecular function	GO:0044093	230	0.011
response to ammonium ion	GO:0060359	71	0.011
regulation of ion transmembrane transport	GO:0034765	121	0.011	Rat
positive regulation of erk1 and erk2 cascade	GO:0070374	29	0.011
cellular response to histamine	GO:0071420	3	0.011
response to vitamin e	GO:0033197	24	0.011
regulation of cell cycle process	GO:0010564	31	0.011	Rat
parturition	GO:0007567	10	0.010
negative regulation of ion transport	GO:0043271	51	0.010
catecholamine secretion	GO:0050432	33	0.010
digestive system process	GO:0022600	24	0.010
embryonic appendage morphogenesis	GO:0035113	4	0.010
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.010
organophosphate biosynthetic process	GO:0090407	143	0.010
regulation of cell growth	GO:0001558	85	0.010
regulation of protein localization	GO:0032880	81	0.010
organ formation	GO:0048645	3	0.010
oligopeptide transport	GO:0006857	4	0.010
regulation of necroptotic process	GO:0060544	2	0.010
cellular nitrogen compound catabolic process	GO:0044270	163	0.010
regulation of vasoconstriction	GO:0019229	44	0.010
regulation of locomotion	GO:0040012	148	0.010
camera type eye morphogenesis	GO:0048593	2	0.010
cell motility	GO:0048870	202	0.010
positive regulation of cellular amine metabolic process	GO:0033240	3	0.010
stress activated protein kinase signaling cascade	GO:0031098	37	0.010
regulation of response to wounding	GO:1903034	69	0.010
action potential	GO:0001508	54	0.010	Rat
urinary bladder smooth muscle contraction	GO:0014832	4	0.010

Kcnv2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability	Func Analog Org
eye and adnexa disease	DOID:1492	0.134	Human
eye disease	DOID:5614	0.134	Human
nervous system disease	DOID:863	0.134	Human
disease of anatomical entity	DOID:7	0.134	Human
sensory system disease	DOID:0050155	0.134	Human
retinal disease	DOID:5679	0.043	Human
retinal degeneration	DOID:8466	0.035
night blindness	DOID:8499	0.020
cardiovascular system disease	DOID:1287	0.020
retinitis pigmentosa	DOID:10584	0.015

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