Rattus norvegicus

0 known processes

Igfals

insulin-like growth factor binding protein, acid labile subunit

(Aliases: Als)

Igfals biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.735
cation transportGO:00068123820.630
response to other organismGO:00517072200.595
response to estrogenGO:00436272320.566
response to estradiolGO:00323551640.553
fatty acid metabolic processGO:0006631990.539
response to decreased oxygen levelsGO:00362932370.536
response to cytokineGO:00340972150.505
response to corticosteroidGO:00319602350.488
carbohydrate derivative metabolic processGO:19011353460.474
carboxylic acid metabolic processGO:00197522890.433
response to external biotic stimulusGO:00432072210.430
ion homeostasisGO:00508012120.418
regulation of calcium ion transportGO:0051924770.412
monocarboxylic acid metabolic processGO:00327871520.407
response to inorganic substanceGO:00100353770.405
response to oxygen levelsGO:00704822650.401
homeostatic processGO:00425923310.397
cell motilityGO:00488702020.373
response to acid chemicalGO:00011012220.356
response to glucocorticoidGO:00513842230.356
positive regulation of multicellular organismal processGO:00512403870.349
response to metal ionGO:00100382530.343
macromolecular complex assemblyGO:00650032730.332
protein complex biogenesisGO:00702712630.305
metal ion homeostasisGO:00550651860.298
response to campGO:0051591910.293
cation homeostasisGO:00550801950.293
brain developmentGO:00074202470.284
response to mechanical stimulusGO:00096121340.277
cellular metal ion homeostasisGO:00068751720.275
organic acid metabolic processGO:00060822920.264
apoptotic processGO:00069153810.262
cellular ketone metabolic processGO:0042180510.258
response to peptide hormoneGO:00434342780.254
response to vitaminGO:00332731310.248
cellular ion homeostasisGO:00068731840.246
pancreatic stellate cell proliferationGO:007234320.243
central nervous system developmentGO:00074173110.242
response to carbohydrateGO:00097431830.235
cellular component assemblyGO:00226073600.234
single organism biosynthetic processGO:00447113420.233
cellular response to external stimulusGO:00714961180.232
response to nutrient levelsGO:00316673700.229
macromolecular complex subunit organizationGO:00439333390.225
regulation of apoptotic processGO:00429813350.220
catabolic processGO:00090563510.217
regulation of metal ion transportGO:00109591180.213
regulation of anatomical structure sizeGO:00900661350.212
cellular response to lipidGO:00713962010.208
gland developmentGO:00487321550.204
response to extracellular stimulusGO:00099913800.203
female pregnancyGO:00075651220.202
muscle system processGO:00030121150.202
cellular cation homeostasisGO:00300031800.201
cellular divalent inorganic cation homeostasisGO:00725031620.198
carbohydrate catabolic processGO:0016052400.188
nitrogen compound transportGO:00717052290.187
protein complex subunit organizationGO:00718223020.184
response to molecule of bacterial originGO:00022371940.183
positive regulation of cell migrationGO:0030335960.183
divalent metal ion transportGO:00708381320.179
cellular homeostasisGO:00197252520.177
calcium ion transportGO:00068161310.177
localization of cellGO:00516742020.170
oxidation reduction processGO:00551143040.167
divalent inorganic cation transportGO:00725111340.166
growthGO:00400071650.166
regulation of ion transportGO:00432692450.163
chemical homeostasisGO:00488782920.163
response to hypoxiaGO:00016662310.163
liver developmentGO:0001889900.160
negative regulation of multicellular organismal processGO:00512412030.158
response to temperature stimulusGO:0009266940.156
cell migrationGO:00164771970.155
steroid metabolic processGO:0008202730.151
glycogen metabolic processGO:0005977230.148
calcium ion homeostasisGO:00550741620.148
ion transmembrane transportGO:00342203650.143
metal ion transportGO:00300012890.142
secretionGO:00469033070.141
regulation of secretion by cellGO:19035302080.141
blood circulationGO:00080151830.140
response to lipopolysaccharideGO:00324961910.137
single organism behaviorGO:00447081300.136
regulation of blood pressureGO:0008217830.136
protein complex assemblyGO:00064612630.135
naphthalene metabolic processGO:001893120.135
response to retinoic acidGO:0032526630.133
regulation of cell migrationGO:00303341280.131
cardiovascular system developmentGO:00723581340.131
regulation of glutamate secretionGO:0014048170.131
synaptic transmissionGO:00072682350.131
response to cesium ionGO:001016420.129
cellular response to steroid hormone stimulusGO:0071383930.127
response to peptideGO:19016522920.126
cellular component biogenesisGO:00440853680.125
divalent inorganic cation homeostasisGO:00725071650.125
positive regulation of cellular component organizationGO:00511302000.125
cellular amino acid metabolic processGO:00065201070.124
cellular response to oxygen containing compoundGO:19017013860.123
cation transmembrane transportGO:00986552630.122
behaviorGO:00076102050.122
glucose metabolic processGO:0006006520.122
cellular response to abiotic stimulusGO:0071214850.122
organic hydroxy compound metabolic processGO:19016151150.121
single organism catabolic processGO:00447122830.121
regulation of cellular localizationGO:00603412630.121
regulation of secretionGO:00510462240.120
positive regulation of cell deathGO:00109421840.119
multicellular organismal signalingGO:0035637440.119
nucleotide metabolic processGO:00091172790.116
transmembrane transportGO:00550854120.115
cellular calcium ion homeostasisGO:00068741600.115
cellular component movementGO:00069282480.114
organ regenerationGO:00311001010.114
response to ethanolGO:00454711620.113
organic substance catabolic processGO:19015753160.113
response to hexoseGO:00097461440.112
nucleobase containing small molecule metabolic processGO:00550863160.112
cellular response to organic cyclic compoundGO:00714072020.112
negative regulation of apoptotic processGO:00430661810.112
response to ketoneGO:19016541820.111
carbohydrate metabolic processGO:00059751300.110
rhythmic processGO:00485111560.109
hepaticobiliary system developmentGO:0061008900.109
negative regulation of response to stimulusGO:00485851550.109
response to dexamethasoneGO:0071548490.109
cell cell signalingGO:00072673350.106
sensory perceptionGO:00076001010.105
agingGO:00075682410.105
response to nutrientGO:00075842480.105
purine nucleotide metabolic processGO:00061632290.103
regulation of blood circulationGO:19035221100.101
defense responseGO:00069521940.101
response to vitamin dGO:0033280340.100
circulatory system processGO:00030131830.098
programmed cell deathGO:00125013920.097
regulation of programmed cell deathGO:00430673410.097
renal system processGO:0003014400.097
negative regulation of cell deathGO:00605482290.095
regulation of cellular component organizationGO:00511283680.094
vitamin d receptor signaling pathwayGO:007056110.094
cytosolic calcium ion homeostasisGO:00514801400.094
protein oligomerizationGO:00512591910.094
positive regulation of locomotionGO:00400171020.093
regulation of locomotionGO:00400121480.093
organic hydroxy compound transportGO:0015850770.093
multi organism reproductive processGO:00447032620.092
cellular carbohydrate metabolic processGO:0044262720.092
organonitrogen compound biosynthetic processGO:19015661670.091
cellular response to alcoholGO:0097306870.089
hexose metabolic processGO:0019318580.089
regulation of tube sizeGO:0035150890.088
lipid biosynthetic processGO:00086101280.088
regulation of homeostatic processGO:00328441010.088
positive regulation of cell motilityGO:2000147970.088
response to cocaineGO:0042220390.087
cellular catabolic processGO:00442482950.084
response to radiationGO:00093141370.084
cellular response to endogenous stimulusGO:00714953770.083
negative regulation of transportGO:00510511360.083
single organism carbohydrate catabolic processGO:0044724400.083
locomotionGO:00400112370.082
regulation of growthGO:00400081050.080
multi multicellular organism processGO:00447061380.080
regulation of cell motilityGO:20001451310.080
response to bacteriumGO:00096172000.079
smooth muscle contractionGO:0006939370.078
response to purine containing compoundGO:00140741260.077
regulation of system processGO:00440572080.077
head developmentGO:00603222470.077
response to biotic stimulusGO:00096072260.077
positive regulation of cytosolic calcium ion concentrationGO:00072041220.077
positive regulation of cellular component movementGO:00512721020.076
reproductive processGO:00224143720.076
alpha amino acid metabolic processGO:1901605710.076
protein localizationGO:00081041910.076
response to coldGO:0009409290.075
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.075
lipid localizationGO:0010876620.073
positive regulation of developmental processGO:00510942830.073
positive regulation of transportGO:00510502450.073
naphthalene containing compound metabolic processGO:009042020.072
cellular chemical homeostasisGO:00550822470.072
smooth muscle cell proliferationGO:0048659770.071
macromolecule catabolic processGO:0009057580.071
organophosphate metabolic processGO:00196373700.070
transmission of nerve impulseGO:0019226420.070
regulation of lipid metabolic processGO:0019216680.069
monoamine transportGO:0015844430.069
cellular response to stressGO:00335542690.069
muscle cell proliferationGO:0033002840.068
positive regulation of cellular biosynthetic processGO:00313282950.068
cellular response to mechanical stimulusGO:0071260480.068
striated muscle tissue developmentGO:0014706580.067
response to vitamin aGO:0033189360.067
muscle tissue developmentGO:0060537580.067
negative regulation of cell proliferationGO:00082851190.066
choline transportGO:001587140.066
macromolecule localizationGO:00330362520.065
response to woundingGO:00096112540.065
fatty acid biosynthetic processGO:0006633330.065
hormone secretionGO:00468791150.064
anion transportGO:00068201780.064
regulation of cellular component movementGO:00512701500.064
regulation of cell growthGO:0001558850.063
neurological system processGO:00508772190.063
monocarboxylic acid transportGO:0015718520.062
regulation of catalytic activityGO:00507903040.062
forebrain developmentGO:0030900980.061
response to insulinGO:00328681330.061
cyclic nucleotide metabolic processGO:0009187800.061
regulation of body fluid levelsGO:0050878900.060
regulation of phosphorus metabolic processGO:00511743490.060
positive regulation of biosynthetic processGO:00098913190.060
feeding behaviorGO:0007631530.059
phenol containing compound metabolic processGO:0018958300.059
muscle structure developmentGO:0061061870.059
catechol containing compound biosynthetic processGO:000971390.058
response to toxic substanceGO:00096361330.057
response to foodGO:0032094270.056
cell growthGO:00160491040.056
catecholamine secretionGO:0050432330.056
single organism carbohydrate metabolic processGO:00447231180.055
neuron differentiationGO:00301823680.055
positive regulation of blood circulationGO:1903524650.054
tonic smooth muscle contractionGO:001482040.054
cellular glucan metabolic processGO:0006073230.054
negative regulation of epithelial cell proliferationGO:0050680160.054
nucleoside phosphate metabolic processGO:00067532830.053
negative regulation of pancreatic stellate cell proliferationGO:200023010.053
cellular response to interleukin 1GO:0071347370.053
positive regulation of secretion by cellGO:19035321280.053
regulation of peptide hormone secretionGO:0090276800.052
catecholamine transportGO:0051937370.052
learning or memoryGO:0007611900.051
response to fluid shear stressGO:0034405160.051
regulation of lipid biosynthetic processGO:0046890380.051
cellular response to campGO:0071320260.050
acylglycerol metabolic processGO:0006639210.050
neutral lipid metabolic processGO:0006638210.049
carboxylic acid biosynthetic processGO:0046394830.049
small molecule catabolic processGO:0044282590.049
organic acid biosynthetic processGO:0016053830.048
ribonucleotide metabolic processGO:00092592310.048
cellular response to interleukin 6GO:007135490.048
negative regulation of macromolecule metabolic processGO:00106052600.047
muscle cell differentiationGO:0042692520.047
response to alkaloidGO:00432791320.047
response to activityGO:0014823730.047
inflammatory responseGO:00069541500.046
cellular lipid metabolic processGO:00442552080.046
cellular response to cytokine stimulusGO:00713451270.046
regulation of synaptic transmissionGO:00508041410.045
negative regulation of protein metabolic processGO:00512481140.045
secretion by cellGO:00329402480.045
organic cyclic compound catabolic processGO:19013611750.045
regulation of transcription from rna polymerase ii promoterGO:00063572340.044
negative regulation of signalingGO:00230571570.044
amine metabolic processGO:0009308380.044
cellular response to extracellular stimulusGO:0031668730.044
regulation of response to woundingGO:1903034690.043
response to hyperoxiaGO:0055093450.043
response to sulfur dioxideGO:001047730.043
negative regulation of programmed cell deathGO:00430691830.043
purine ribonucleotide metabolic processGO:00091502270.043
cellular nitrogen compound catabolic processGO:00442701630.043
generation of precursor metabolites and energyGO:0006091620.043
positive regulation of nucleobase containing compound metabolic processGO:00459353190.043
positive regulation of vasodilationGO:0045909290.043
positive regulation of long term synaptic potentiationGO:190027340.043
response to interleukin 1GO:0070555550.042
response to monosaccharideGO:00342841590.042
cellular response to glucocorticoid stimulusGO:0071385680.042
cellular response to vitamin dGO:0071305120.041
telencephalon developmentGO:0021537620.041
positive regulation of programmed cell deathGO:00430681570.041
cellular response to insulin stimulusGO:0032869810.041
response to starvationGO:0042594590.041
behavioral response to nicotineGO:003509520.041
regulation of cell cycleGO:0051726730.040
mrna transcriptionGO:000929920.040
signal releaseGO:00230611450.040
monocarboxylic acid biosynthetic processGO:0072330480.040
regenerationGO:00310991630.040
vitamin a metabolic processGO:000677620.040
regulation of protein localizationGO:0032880810.040
positive regulation of cell proliferationGO:00082842490.039
long chain fatty acid metabolic processGO:0001676320.039
positive regulation of gene expressionGO:00106282440.039
positive regulation of immune system processGO:0002684900.039
response to corticosteroneGO:0051412400.039
cellular sodium ion homeostasisGO:000688340.039
tissue developmentGO:00098882520.038
developmental process involved in reproductionGO:00030061590.038
carbohydrate derivative biosynthetic processGO:19011371240.038
response to nicotineGO:0035094510.038
lipid transportGO:0006869610.038
regulation of muscle system processGO:0090257790.037
organophosphate biosynthetic processGO:00904071430.037
ribose phosphate metabolic processGO:00196932350.037
positive regulation of nucleic acid templated transcriptionGO:19035081970.037
pyruvate metabolic processGO:0006090270.037
positive regulation of cell projection organizationGO:00313461110.037
potassium ion transportGO:0006813970.036
heart contractionGO:0060047570.036
glucan metabolic processGO:0044042230.036
response to organophosphorusGO:00466831020.035
glycoside transportGO:190165620.035
purine ribonucleotide biosynthetic processGO:0009152810.035
monovalent inorganic cation transportGO:00156721720.035
cell projection organizationGO:00300303020.035
response to glucoseGO:00097491360.035
regulation of phagocytosis engulfmentGO:006009940.035
myeloid leukocyte differentiationGO:0002573200.035
trichloroethylene metabolic processGO:001897910.035
positive regulation of cell differentiationGO:00455972170.035
response to increased oxygen levelsGO:0036296450.035
multicellular organism reproductionGO:00325042330.034
positive regulation of apoptotic processGO:00430651540.034
memoryGO:0007613540.034
response to testosteroneGO:0033574550.034
response to transition metal nanoparticleGO:19902671220.034
organic hydroxy compound biosynthetic processGO:1901617510.034
regulation of cell proliferationGO:00421273590.034
positive regulation of phosphorus metabolic processGO:00105622620.034
artery smooth muscle contractionGO:001482440.033
response to amphetamineGO:0001975250.033
positive regulation of phagocytosis engulfmentGO:006010040.033
organ morphogenesisGO:0009887750.033
amine transportGO:0015837570.033
vascular process in circulatory systemGO:0003018960.033
purine nucleoside catabolic processGO:00061521240.033
regulation of cellular ketone metabolic processGO:0010565270.032
cellular response to corticosteroid stimulusGO:0071384690.032
developmental growthGO:00485891000.032
regulation of amine transportGO:0051952540.032
glycosyl compound metabolic processGO:19016571820.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
maintenance of locationGO:0051235170.032
regulation of cellular protein metabolic processGO:00322682670.032
response to lead ionGO:0010288330.032
cellular polysaccharide metabolic processGO:0044264230.032
cellular amine metabolic processGO:0044106380.032
protein localization to organelleGO:0033365570.032
protein secretionGO:0009306340.031
positive regulation of secretionGO:00510471400.031
cartilage condensationGO:000150220.031
positive regulation of renin secretion into blood streamGO:190013510.031
circulatory system developmentGO:00723591340.031
regulation of cellular amino acid metabolic processGO:000652120.031
triglyceride metabolic processGO:0006641210.031
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
response to catecholamineGO:0071869160.031
regulation of blood vessel sizeGO:0050880890.031
gamma aminobutyric acid secretionGO:001405160.031
cofactor metabolic processGO:0051186950.030
regulation of muscle contractionGO:0006937530.030
regulation of fatty acid metabolic processGO:0019217180.030
embryonic cranial skeleton morphogenesisGO:004870120.030
positive regulation of cellular component biogenesisGO:0044089550.030
positive regulation of cell growthGO:0030307440.029
regulation of renal sodium excretionGO:0035813200.029
placenta developmentGO:0001890220.029
regulation of signal transductionGO:00099663180.029
regulation of intracellular signal transductionGO:19025312180.029
cellular response to organonitrogen compoundGO:00714171970.029
intracellular signal transductionGO:00355563140.028
rna metabolic processGO:00160704060.028
response to triglycerideGO:003401430.028
cellular response to retinoic acidGO:0071300270.028
muscle contractionGO:0006936880.028
heart developmentGO:0007507720.028
myeloid cell differentiationGO:0030099220.028
regulation of carbohydrate metabolic processGO:0006109410.028
biological adhesionGO:00226101100.028
regulation of peptide transportGO:0090087870.028
single organism organelle organizationGO:19025891800.028
response to fatty acidGO:0070542650.027
insulin like growth factor receptor signaling pathwayGO:004800930.027
purine ribonucleoside catabolic processGO:00461301240.027
negative regulation of smooth muscle cell proliferationGO:0048662210.027
organophosphate catabolic processGO:00464341480.027
regulation of protein phosphorylationGO:00019321830.027
cellular response to hormone stimulusGO:00328702470.027
amide transportGO:00428861050.027
regulation of adenylate cyclase activityGO:0045761180.027
energy reserve metabolic processGO:0006112250.027
organelle organizationGO:00069962660.027
protein homooligomerizationGO:0051260910.027
antibiotic transportGO:004289120.027
cognitionGO:0050890920.026
inorganic ion transmembrane transportGO:00986602290.026
skeletal muscle tissue developmentGO:0007519310.026
signal transduction by phosphorylationGO:00230141440.026
regulation of neuron deathGO:19012141150.026
peptide secretionGO:0002790860.026
regulation of vasodilationGO:0042312360.026
peptide hormone secretionGO:0030072840.026
cellular protein localizationGO:00346131220.026
organic anion transportGO:00157111320.026
cardiocyte differentiationGO:0035051220.026
immune system developmentGO:0002520410.026
heart processGO:0003015570.026
monosaccharide metabolic processGO:0005996610.025
circadian rhythmGO:0007623880.025
regulation of myeloid cell differentiationGO:0045637120.025
phenol containing compound biosynthetic processGO:004618990.025
response to amineGO:0014075460.025
purine containing compound metabolic processGO:00725212530.025
urogenital system developmentGO:0001655780.025
anatomical structure formation involved in morphogenesisGO:0048646830.025
vasoconstrictionGO:0042310540.025
regulation of phosphate metabolic processGO:00192203490.025
cellular response to acid chemicalGO:0071229750.025
action potentialGO:0001508540.025
positive regulation of homeostatic processGO:0032846490.025
regulation of fat cell differentiationGO:004559830.025
glycolytic processGO:0006096170.025
response to interleukin 6GO:0070741130.025
bile acid and bile salt transportGO:0015721120.025
tube developmentGO:0035295890.025
multicellular organism growthGO:003526410.024
nucleobase containing compound catabolic processGO:00346551520.024
ribose phosphate biosynthetic processGO:0046390870.024
negative regulation of cellular metabolic processGO:00313242810.024
pyridine containing compound metabolic processGO:0072524320.024
regulation of ion homeostasisGO:2000021630.024
rna biosynthetic processGO:00327743800.024
response to oxidative stressGO:00069791860.024
response to heatGO:0009408600.024
small molecule biosynthetic processGO:00442831240.023
positive regulation of nervous system developmentGO:00519621780.023
response to calcium ionGO:0051592590.023
purine nucleotide biosynthetic processGO:0006164830.023
negative regulation of synaptic transmission dopaminergicGO:003222740.023
positive regulation of nitrogen compound metabolic processGO:00511733340.023
regulation of transcription dna templatedGO:00063553740.023
carboxylic acid transportGO:00469421150.023
purine ribonucleoside metabolic processGO:00461281680.023
single organism reproductive processGO:00447022970.022
coenzyme metabolic processGO:0006732860.022
positive regulation of rna biosynthetic processGO:19026801970.022
response to monoamineGO:0071867170.022
inorganic cation transmembrane transportGO:00986622020.022
positive regulation of rna metabolic processGO:00512542030.022
cellular response to nitrogen compoundGO:19016992100.022
positive regulation of neuron differentiationGO:00456661260.022
regulation of vasculature developmentGO:1901342440.022
lateral ventricle developmentGO:002167010.022
acute inflammatory responseGO:0002526580.022
peptidyl tyrosine modificationGO:0018212720.022
positive regulation of renal sodium excretionGO:0035815100.022
protein tetramerizationGO:0051262380.022
renal system developmentGO:0072001670.021
sulfur compound transportGO:007234880.021
neuron deathGO:00709971270.021
regulation of peptide secretionGO:0002791820.021
reproductionGO:00000032450.021
regulation of nucleotide metabolic processGO:00061401170.021
cyclic purine nucleotide metabolic processGO:0052652620.021
regulation of cellular component biogenesisGO:0044087860.021
purine containing compound biosynthetic processGO:0072522850.020
exogenous drug catabolic processGO:004273810.020
negative regulation of ion transportGO:0043271510.020
heterocycle catabolic processGO:00467001670.020
regulation of molecular functionGO:00650093980.020
detection of external stimulusGO:0009581130.020
cardiac muscle cell developmentGO:0055013160.020
ribonucleoside triphosphate catabolic processGO:00092031220.020
positive regulation of phosphate metabolic processGO:00459372620.020
nucleoside metabolic processGO:00091161790.020
response to osmotic stressGO:0006970420.020
sensory perception of mechanical stimulusGO:0050954170.020
positive regulation of cell developmentGO:00107201760.020
cellular response to transforming growth factor beta stimulusGO:0071560410.019
glial cell differentiationGO:0010001650.019
negative regulation of acute inflammatory responseGO:000267440.019
sensory organ developmentGO:0007423740.019
hormone metabolic processGO:0042445690.019
negative regulation of secretionGO:0051048820.019
steroid biosynthetic processGO:0006694480.019
peptide transportGO:0015833970.019
sequestering of metal ionGO:005123890.019
activation of jak2 kinase activityGO:004297720.018
mechanoreceptor differentiationGO:004249020.018
regulation of anatomical structure morphogenesisGO:00226031410.018

Igfals disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060
nervous system diseaseDOID:86300.060
hypothyroidismDOID:145900.045
thyroid gland diseaseDOID:5000.045
congenital hypothyroidismDOID:005032800.045
endocrine system diseaseDOID:2800.045
disease of metabolismDOID:001466700.027
cardiovascular system diseaseDOID:128700.024
sensory system diseaseDOID:005015500.022