IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Ghitm

growth hormone inducible transmembrane protein

(Aliases: MGC94737,MICS1)

Entrez: 290596
Ensembl: ENSRNOG00000013961
RGD: 1359301
UniProtKB: Q5XIA8

Process Predictions
Disease Predictions

Ghitm biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular respiration	GO:0045333	21	0.252
oxidation reduction process	GO:0055114	304	0.188
energy derivation by oxidation of organic compounds	GO:0015980	46	0.183
cofactor metabolic process	GO:0051186	95	0.170
cellular response to stress	GO:0033554	269	0.158
catabolic process	GO:0009056	351	0.156
aging	GO:0007568	241	0.135
dicarboxylic acid metabolic process	GO:0043648	42	0.125
programmed cell death	GO:0012501	392	0.124
nucleoside phosphate metabolic process	GO:0006753	283	0.116
aerobic respiration	GO:0009060	13	0.100
response to other organism	GO:0051707	220	0.090
response to oxidative stress	GO:0006979	186	0.090
homeostatic process	GO:0042592	331	0.085
regulation of apoptotic process	GO:0042981	335	0.083
generation of precursor metabolites and energy	GO:0006091	62	0.082
organophosphate metabolic process	GO:0019637	370	0.081
oxoacid metabolic process	GO:0043436	290	0.080
reproduction	GO:0000003	245	0.080
nucleobase containing small molecule metabolic process	GO:0055086	316	0.079
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.074
apoptotic process	GO:0006915	381	0.064
carboxylic acid metabolic process	GO:0019752	289	0.063
response to inorganic substance	GO:0010035	377	0.059
regulation of programmed cell death	GO:0043067	341	0.059
ion transmembrane transport	GO:0034220	365	0.054
nucleoside monophosphate metabolic process	GO:0009123	93	0.052
regulation of molecular function	GO:0065009	398	0.051
response to hydrogen peroxide	GO:0042542	89	0.050
negative regulation of programmed cell death	GO:0043069	183	0.048
nucleotide metabolic process	GO:0009117	279	0.048
response to reactive oxygen species	GO:0000302	120	0.046
cellular catabolic process	GO:0044248	295	0.046
nitrogen compound transport	GO:0071705	229	0.046
single organism reproductive process	GO:0044702	297	0.045
cellular homeostasis	GO:0019725	252	0.043
purine nucleoside metabolic process	GO:0042278	169	0.042
reproductive process	GO:0022414	372	0.041
cellular response to oxidative stress	GO:0034599	76	0.041
negative regulation of signaling	GO:0023057	157	0.040
organic acid metabolic process	GO:0006082	292	0.039
regulation of cellular component organization	GO:0051128	368	0.038
multicellular organism reproduction	GO:0032504	233	0.038
hydrogen peroxide metabolic process	GO:0042743	13	0.038
cation transport	GO:0006812	382	0.038
regulation of protein metabolic process	GO:0051246	289	0.038
negative regulation of cell death	GO:0060548	229	0.036
ribose phosphate metabolic process	GO:0019693	235	0.036
purine ribonucleoside metabolic process	GO:0046128	168	0.036
organelle organization	GO:0006996	266	0.035
positive regulation of molecular function	GO:0044093	230	0.035
single organism biosynthetic process	GO:0044711	342	0.034
purine containing compound metabolic process	GO:0072521	253	0.034
transmembrane transport	GO:0055085	412	0.034
citrate metabolic process	GO:0006101	3	0.033
carbohydrate derivative metabolic process	GO:1901135	346	0.033
multi organism reproductive process	GO:0044703	262	0.032
response to biotic stimulus	GO:0009607	226	0.031
proteolysis	GO:0006508	175	0.030
metal ion transport	GO:0030001	289	0.030
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	7	0.029
response to nutrient levels	GO:0031667	370	0.029
negative regulation of apoptotic process	GO:0043066	181	0.029
cellular response to reactive oxygen species	GO:0034614	55	0.029
mitochondrion organization	GO:0007005	35	0.028
multicellular organismal reproductive process	GO:0048609	233	0.028
growth	GO:0040007	165	0.028
tricarboxylic acid metabolic process	GO:0072350	10	0.027
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.027
cellular chemical homeostasis	GO:0055082	247	0.027
negative regulation of protein metabolic process	GO:0051248	114	0.027
reactive oxygen species metabolic process	GO:0072593	37	0.027
negative regulation of signal transduction	GO:0009968	83	0.027
ion homeostasis	GO:0050801	212	0.026
autophagy	GO:0006914	19	0.026
mitochondrial calcium ion transport	GO:0006851	2	0.026
organonitrogen compound catabolic process	GO:1901565	179	0.025
response to decreased oxygen levels	GO:0036293	237	0.025
regulation of membrane potential	GO:0042391	110	0.024
chemical homeostasis	GO:0048878	292	0.024
response to external biotic stimulus	GO:0043207	221	0.024
multicellular organismal homeostasis	GO:0048871	49	0.024
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.024
heme biosynthetic process	GO:0006783	4	0.023
response to interleukin 1	GO:0070555	55	0.023
response to antibiotic	GO:0046677	39	0.023
spindle organization	GO:0007051	2	0.022
regulation of nucleic acid templated transcription	GO:1903506	380	0.022
response to oxygen levels	GO:0070482	265	0.022
cation homeostasis	GO:0055080	195	0.021
macromolecular complex assembly	GO:0065003	273	0.021
anatomical structure morphogenesis	GO:0009653	298	0.021
glycosyl compound metabolic process	GO:1901657	182	0.021
regulation of hydrolase activity	GO:0051336	143	0.021
negative regulation of cell communication	GO:0010648	158	0.021
macromolecule catabolic process	GO:0009057	58	0.020
l glutamate import	GO:0051938	2	0.020
regulation of phosphate metabolic process	GO:0019220	349	0.020
sulfur compound metabolic process	GO:0006790	70	0.020
positive regulation of multicellular organismal process	GO:0051240	387	0.019
cellular response to oxygen containing compound	GO:1901701	386	0.019
regulation of rna biosynthetic process	GO:2001141	381	0.018
cation transmembrane transport	GO:0098655	263	0.018
cellular nitrogen compound catabolic process	GO:0044270	163	0.018
cellular cation homeostasis	GO:0030003	180	0.018
pigment biosynthetic process	GO:0046148	4	0.018
negative regulation of cellular protein metabolic process	GO:0032269	106	0.017
thioester metabolic process	GO:0035383	28	0.017
organic cyclic compound catabolic process	GO:1901361	175	0.017
regulation of transcription dna templated	GO:0006355	374	0.017
cellular amino acid metabolic process	GO:0006520	107	0.017
response to toxic substance	GO:0009636	133	0.017
response to hypoxia	GO:0001666	231	0.016
rna biosynthetic process	GO:0032774	380	0.016
sexual reproduction	GO:0019953	148	0.016
negative regulation of phosphorus metabolic process	GO:0010563	80	0.016
response to estrogen	GO:0043627	232	0.016
protein complex assembly	GO:0006461	263	0.016
regulation of growth	GO:0040008	105	0.016
nucleocytoplasmic transport	GO:0006913	48	0.016
cellular component biogenesis	GO:0044085	368	0.016
regulation of cellular protein metabolic process	GO:0032268	267	0.016
regulation of catalytic activity	GO:0050790	304	0.016
negative regulation of cellular component organization	GO:0051129	83	0.016
purine containing compound catabolic process	GO:0072523	138	0.016
modification dependent protein catabolic process	GO:0019941	14	0.015
tricarboxylic acid cycle	GO:0006099	11	0.015
multi multicellular organism process	GO:0044706	138	0.015
brain development	GO:0007420	247	0.015
metal ion homeostasis	GO:0055065	186	0.015
reactive nitrogen species metabolic process	GO:2001057	1	0.015
positive regulation of biosynthetic process	GO:0009891	319	0.015
divalent metal ion transport	GO:0070838	132	0.015
positive regulation of apoptotic process	GO:0043065	154	0.015
response to wounding	GO:0009611	254	0.015
single organism catabolic process	GO:0044712	283	0.015
response to cytokine	GO:0034097	215	0.015
toxin transport	GO:1901998	3	0.014
rna metabolic process	GO:0016070	406	0.014
nucleoside metabolic process	GO:0009116	179	0.014
single organism intracellular transport	GO:1902582	166	0.014
intracellular transport	GO:0046907	185	0.014
cellular response to superoxide	GO:0071451	6	0.014
gamete generation	GO:0007276	124	0.014
purine ribonucleotide metabolic process	GO:0009150	227	0.014
cell redox homeostasis	GO:0045454	1	0.014
calcium ion transport	GO:0006816	131	0.014
acyl coa metabolic process	GO:0006637	28	0.014
purine nucleotide metabolic process	GO:0006163	229	0.014
cellular ion homeostasis	GO:0006873	184	0.014
protein processing	GO:0016485	68	0.013
negative regulation of cellular metabolic process	GO:0031324	281	0.013
nucleic acid transport	GO:0050657	3	0.013
protein homooligomerization	GO:0051260	91	0.013
regulation of cell proliferation	GO:0042127	359	0.013
microtubule based process	GO:0007017	36	0.013
regulation of response to stress	GO:0080134	126	0.012
negative regulation of molecular function	GO:0044092	133	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
cellular metal ion homeostasis	GO:0006875	172	0.012
ribonucleoside metabolic process	GO:0009119	174	0.012
neurotransmitter uptake	GO:0001504	3	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.012
sperm egg recognition	GO:0035036	1	0.012
ribonucleotide metabolic process	GO:0009259	231	0.012
protein maturation	GO:0051604	68	0.012
regulation of kinase activity	GO:0043549	117	0.012
mitotic spindle organization	GO:0007052	2	0.012
macromolecule localization	GO:0033036	252	0.012
cytoplasmic transport	GO:0016482	115	0.012
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.012
hematopoietic progenitor cell differentiation	GO:0002244	2	0.012
regulation of transferase activity	GO:0051338	123	0.011
male gamete generation	GO:0048232	99	0.011
protein transport	GO:0015031	132	0.011
nicotinamide nucleotide metabolic process	GO:0046496	28	0.011
immune system process	GO:0002376	204	0.011
negative regulation of protein maturation	GO:1903318	47	0.011
atp metabolic process	GO:0046034	72	0.011
cellular macromolecule localization	GO:0070727	122	0.011
response to extracellular stimulus	GO:0009991	380	0.011
amine metabolic process	GO:0009308	38	0.011
transcription dna templated	GO:0006351	377	0.011
apoptotic signaling pathway	GO:0097190	27	0.011
positive regulation of protein modification process	GO:0031401	142	0.011
central nervous system development	GO:0007417	311	0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043154	17	0.011
cellular component assembly	GO:0022607	360	0.011
organic substance catabolic process	GO:1901575	316	0.011
response to cold	GO:0009409	29	0.011
response to vitamin	GO:0033273	131	0.011
monovalent inorganic cation transport	GO:0015672	172	0.011
alpha amino acid metabolic process	GO:1901605	71	0.011
lipid storage	GO:0019915	1	0.010
cellular amine metabolic process	GO:0044106	38	0.010
positive regulation of phosphorus metabolic process	GO:0010562	262	0.010
single organism organelle organization	GO:1902589	180	0.010
reproductive structure development	GO:0048608	128	0.010
negative regulation of macromolecule metabolic process	GO:0010605	260	0.010
regulation of multicellular organismal development	GO:2000026	376	0.010
organophosphate catabolic process	GO:0046434	148	0.010
regulation of intracellular signal transduction	GO:1902531	218	0.010

Ghitm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.060
nervous system disease	DOID:863	0.060
central nervous system disease	DOID:331	0.016

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