Rattus norvegicus

54 known processes

Sqstm1

sequestosome 1

(Aliases: Osi,ZIP3,ZIP)

Sqstm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrient levelsGO:00316673700.312
Human
catabolic processGO:00090563510.263
Human
response to extracellular stimulusGO:00099913800.250
Human
protein complex assemblyGO:00064612630.209
response to nutrientGO:00075842480.163
carboxylic acid metabolic processGO:00197522890.148
tissue developmentGO:00098882520.146
protein complex subunit organizationGO:00718223020.138
regulation of stress activated protein kinase signaling cascadeGO:0070302230.133
cellular response to oxygen containing compoundGO:19017013860.133
nucleic acid templated transcriptionGO:00976593790.122
protein transportGO:00150311320.108
cellular response to stressGO:00335542690.106
Human
immune system processGO:00023762040.098
protein localizationGO:00081041910.097
positive regulation of response to stimulusGO:00485842850.096
Human
cellular component biogenesisGO:00440853680.093
response to purine containing compoundGO:00140741260.089
single organism catabolic processGO:00447122830.088
Human
programmed cell deathGO:00125013920.085
negative regulation of programmed cell deathGO:00430691830.084
anatomical structure morphogenesisGO:00096532980.081
negative regulation of cell deathGO:00605482290.081
cell type specific apoptotic processGO:00972851340.080
cellular amino acid metabolic processGO:00065201070.080
positive regulation of phosphate metabolic processGO:00459372620.080
oxoacid metabolic processGO:00434362900.079
cellular response to nitrogen compoundGO:19016992100.078
reproductive processGO:00224143720.077
organic substance catabolic processGO:19015753160.077
proteolysisGO:00065081750.076
regulation of secretionGO:00510462240.074
regulation of phosphorus metabolic processGO:00511743490.073
cellular catabolic processGO:00442482950.072
Human
macromolecular complex assemblyGO:00650032730.070
protein complex biogenesisGO:00702712630.068
regulation of cell proliferationGO:00421273590.067
positive regulation of signalingGO:00230562700.066
negative regulation of apoptotic processGO:00430661810.064
single organism reproductive processGO:00447022970.062
cellular response to endogenous stimulusGO:00714953770.061
response to peptide hormoneGO:00434342780.061
regulation of molecular functionGO:00650093980.060
regulation of protein metabolic processGO:00512462890.060
cellular response to organonitrogen compoundGO:00714171970.059
macromolecule localizationGO:00330362520.058
regulation of catalytic activityGO:00507903040.058
apoptotic processGO:00069153810.057
protein heterooligomerizationGO:0051291890.056
cellular response to peptide hormone stimulusGO:00713751200.056
regulation of phosphorylationGO:00423252480.055
stress activated mapk cascadeGO:0051403350.055
regulation of cellular response to stressGO:0080135490.054
Human
regulation of programmed cell deathGO:00430673410.054
signal transduction by phosphorylationGO:00230141440.054
oxidation reduction processGO:00551143040.054
response to other organismGO:00517072200.052
positive regulation of developmental processGO:00510942830.052
defense responseGO:00069521940.052
positive regulation of cellular biosynthetic processGO:00313282950.051
positive regulation of phosphorus metabolic processGO:00105622620.051
reactive oxygen species metabolic processGO:0072593370.050
regulation of response to stressGO:00801341260.050
Human
cellular component assemblyGO:00226073600.049
stress activated protein kinase signaling cascadeGO:0031098370.049
positive regulation of protein phosphorylationGO:00019341350.049
neuron deathGO:00709971270.048
positive regulation of cellular protein metabolic processGO:00322701670.048
rna biosynthetic processGO:00327743800.047
regulation of apoptotic processGO:00429813350.046
central nervous system developmentGO:00074173110.046
regulation of rna biosynthetic processGO:20011413810.046
response to cytokineGO:00340972150.046
response to growth factorGO:00708481890.045
regulation of secretion by cellGO:19035302080.045
positive regulation of gene expressionGO:00106282440.045
cellular response to peptideGO:19016531330.045
cellular ketone metabolic processGO:0042180510.044
organic acid metabolic processGO:00060822920.043
establishment of protein localizationGO:00451841410.043
positive regulation of multicellular organismal processGO:00512403870.043
protein oligomerizationGO:00512591910.043
regulation of intracellular signal transductionGO:19025312180.043
Human
cellular component movementGO:00069282480.043
cellular response to cytokine stimulusGO:00713451270.043
response to oxygen levelsGO:00704822650.042
regulation of rna metabolic processGO:00512523910.042
secretion by cellGO:00329402480.042
cell motilityGO:00488702020.042
cellular response to hormone stimulusGO:00328702470.042
response to glucocorticoidGO:00513842230.042
response to corticosteroidGO:00319602350.042
neurological system processGO:00508772190.041
mapk cascadeGO:00001651400.041
intracellular signal transductionGO:00355563140.041
Human
immune responseGO:00069551040.041
positive regulation of cell communicationGO:00106472710.041
Human
response to organophosphorusGO:00466831020.041
positive regulation of signal transductionGO:00099671750.041
gland developmentGO:00487321550.040
single organism intracellular transportGO:19025821660.040
regenerationGO:00310991630.039
tissue remodelingGO:0048771400.038
cytokine productionGO:0001816610.038
transcription from rna polymerase ii promoterGO:00063662520.038
response to decreased oxygen levelsGO:00362932370.038
response to hypoxiaGO:00016662310.038
positive regulation of mapk cascadeGO:0043410920.037
regulation of transcription dna templatedGO:00063553740.037
secretionGO:00469033070.036
positive regulation of protein metabolic processGO:00512471780.036
cellular macromolecule localizationGO:00707271220.036
regulation of phosphate metabolic processGO:00192203490.035
regulation of nervous system developmentGO:00519602640.035
negative regulation of neuron apoptotic processGO:0043524450.035
negative regulation of metabolic processGO:00098923310.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
response to inorganic substanceGO:00100353770.034
regulation of cellular protein metabolic processGO:00322682670.034
epithelium developmentGO:0060429960.034
cell morphogenesis involved in differentiationGO:00009041190.034
ribonucleotide metabolic processGO:00092592310.034
macromolecular complex subunit organizationGO:00439333390.034
cellular modified amino acid metabolic processGO:0006575610.033
positive regulation of cellular amino acid metabolic processGO:004576410.033
cation transportGO:00068123820.033
cellular response to extracellular stimulusGO:0031668730.032
Human
multi organism reproductive processGO:00447032620.032
response to starvationGO:0042594590.032
Human
negative regulation of macromolecule metabolic processGO:00106052600.032
membrane organizationGO:0061024940.031
regulation of anatomical structure morphogenesisGO:00226031410.031
hepaticobiliary system developmentGO:0061008900.031
positive regulation of nervous system developmentGO:00519621780.030
regulation of kinase activityGO:00435491170.030
regulation of growthGO:00400081050.030
rna metabolic processGO:00160704060.029
chemical homeostasisGO:00488782920.029
multicellular organism growthGO:003526410.029
response to biotic stimulusGO:00096072260.029
regulation of cellular amine metabolic processGO:003323880.029
regulation of neuron deathGO:19012141150.029
regulation of anatomical structure sizeGO:00900661350.029
response to molecule of bacterial originGO:00022371940.029
regulation of transferase activityGO:00513381230.028
positive regulation of transcription dna templatedGO:00458931970.028
transcription dna templatedGO:00063513770.028
negative regulation of signalingGO:00230571570.028
lymphocyte activationGO:0046649430.028
regulation of cellular amino acid metabolic processGO:000652120.028
regulation of neuron differentiationGO:00456642080.028
positive regulation of catalytic activityGO:00430851840.028
gonad developmentGO:00084061040.027
organophosphate metabolic processGO:00196373700.027
positive regulation of cellular component organizationGO:00511302000.027
positive regulation of molecular functionGO:00440932300.027
regulation of stress activated mapk cascadeGO:0032872230.027
regulation of signal transductionGO:00099663180.027
Human
cellular protein localizationGO:00346131220.027
response to lead ionGO:0010288330.027
regulation of cellular component organizationGO:00511283680.027
positive regulation of cellular amine metabolic processGO:003324030.027
amine metabolic processGO:0009308380.027
response to bacteriumGO:00096172000.027
regulation of protein transportGO:0051223680.026
multicellular organismal reproductive processGO:00486092330.026
regulation of response to external stimulusGO:00321011060.026
Human
agingGO:00075682410.026
carbohydrate metabolic processGO:00059751300.026
regulation of protein localizationGO:0032880810.025
cellular response to growth factor stimulusGO:00713631620.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
regulation of immune responseGO:0050776550.025
regulation of neuron apoptotic processGO:0043523830.025
behaviorGO:00076102050.024
response to carbohydrateGO:00097431830.024
positive regulation of cell proliferationGO:00082842490.024
response to monosaccharideGO:00342841590.024
regulation of cell projection organizationGO:00313441750.024
response to woundingGO:00096112540.024
regulation of multicellular organismal developmentGO:20000263760.024
carbohydrate derivative metabolic processGO:19011353460.024
cell cell signalingGO:00072673350.024
metal ion transportGO:00300012890.023
single organism biosynthetic processGO:00447113420.023
alpha amino acid metabolic processGO:1901605710.023
response to peptideGO:19016522920.023
cellular response to organic cyclic compoundGO:00714072020.023
regulation of protein phosphorylationGO:00019321830.023
gamete generationGO:00072761240.023
positive regulation of phosphorylationGO:00423271770.023
positive regulation of biosynthetic processGO:00098913190.022
regulation of establishment of protein localizationGO:0070201690.022
single organism carbohydrate metabolic processGO:00447231180.022
reproductive system developmentGO:00614581280.022
t helper 1 type immune responseGO:004208810.022
regulation of protein modification processGO:00313991940.022
response to insulinGO:00328681330.022
negative regulation of multicellular organismal processGO:00512412030.022
response to metal ionGO:00100382530.022
response to external biotic stimulusGO:00432072210.022
negative regulation of cell proliferationGO:00082851190.022
positive regulation of cell differentiationGO:00455972170.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
liver developmentGO:0001889900.021
response to estrogenGO:00436272320.021
regulation of map kinase activityGO:0043405530.021
negative regulation of gene expressionGO:00106291990.021
reproductive structure developmentGO:00486081280.021
cardiovascular system developmentGO:00723581340.021
response to vitaminGO:00332731310.021
neuron apoptotic processGO:0051402880.021
response to ethanolGO:00454711620.021
regulation of tube sizeGO:0035150890.021
regulation of immune system processGO:00026821230.021
small molecule biosynthetic processGO:00442831240.021
regulation of blood vessel sizeGO:0050880890.021
generation of precursor metabolites and energyGO:0006091620.021
heart developmentGO:0007507720.021
response to toxic substanceGO:00096361330.021
developmental process involved in reproductionGO:00030061590.021
regulation of cell differentiationGO:00455953200.021
cellular response to external stimulusGO:00714961180.020
Human
multicellular organism reproductionGO:00325042330.020
cell migrationGO:00164771970.020
anatomical structure formation involved in morphogenesisGO:0048646830.020
cellular chemical homeostasisGO:00550822470.020
regulation of cellular localizationGO:00603412630.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
muscle cell proliferationGO:0033002840.020
female pregnancyGO:00075651220.020
cellular amide metabolic processGO:0043603440.020
circadian rhythmGO:0007623880.020
positive regulation of immune responseGO:0050778420.020
development of primary sexual characteristicsGO:00451371070.020
negative regulation of cellular metabolic processGO:00313242810.020
localization of cellGO:00516742020.020
cellular response to insulin stimulusGO:0032869810.020
regulation of hormone levelsGO:00108171870.019
immune system developmentGO:0002520410.019
organelle organizationGO:00069962660.019
protein phosphorylationGO:00064683450.019
positive regulation of cell projection organizationGO:00313461110.019
hematopoietic or lymphoid organ developmentGO:0048534360.019
head developmentGO:00603222470.019
growthGO:00400071650.019
regulation of mapk cascadeGO:00434081160.019
response to acid chemicalGO:00011012220.019
cellular amine metabolic processGO:0044106380.019
vascular process in circulatory systemGO:0003018960.019
response to temperature stimulusGO:0009266940.019
cellular component morphogenesisGO:00329891550.018
sodium ion transportGO:0006814820.018
autophagic cell deathGO:004810240.018
tube developmentGO:0035295890.018
response to mechanical stimulusGO:00096121340.018
reproductionGO:00000032450.018
single organism membrane organizationGO:0044802740.018
sexual reproductionGO:00199531480.018
positive regulation of protein modification processGO:00314011420.018
innate immune responseGO:0045087350.018
negative regulation of cellular component organizationGO:0051129830.018
eye developmentGO:0001654500.018
positive regulation of rna biosynthetic processGO:19026801970.018
hemopoiesisGO:0030097340.018
nucleoside phosphate metabolic processGO:00067532830.018
glycosyl compound metabolic processGO:19016571820.018
cell projection organizationGO:00300303020.018
glycogen metabolic processGO:0005977230.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
macroautophagyGO:001623640.017
Human
regulation of neuron projection developmentGO:00109751610.017
cellular homeostasisGO:00197252520.017
negative regulation of cell differentiationGO:0045596990.017
cellular response to nutrient levelsGO:0031669600.017
Human
nucleotide metabolic processGO:00091172790.017
heterocycle catabolic processGO:00467001670.017
response to oxidative stressGO:00069791860.017
organ regenerationGO:00311001010.017
male gamete generationGO:0048232990.017
negative regulation of response to stimulusGO:00485851550.017
positive regulation of transferase activityGO:0051347810.017
monovalent inorganic cation transportGO:00156721720.017
positive regulation of transportGO:00510502450.017
intracellular transportGO:00469071850.016
regulation of catabolic processGO:00098941130.016
Human
positive regulation of programmed cell deathGO:00430681570.016
cell projection morphogenesisGO:00488581230.016
regulation of cellular ketone metabolic processGO:0010565270.016
lipid metabolic processGO:00066292830.016
response to ketoneGO:19016541820.016
response to interleukin 1GO:0070555550.016
chemosensory behaviorGO:000763520.016
peptide metabolic processGO:0006518320.016
negative regulation of neuron deathGO:1901215690.016
gastrulationGO:000736920.016
response to hexoseGO:00097461440.016
regulation of t cell activationGO:0050863230.016
macromolecule catabolic processGO:0009057580.016
protein processingGO:0016485680.016
cellular lipid metabolic processGO:00442552080.016
immune effector processGO:0002252530.016
regulation of proteasomal protein catabolic processGO:006113640.015
regulation of protein maturationGO:1903317500.015
positive regulation of protein serine threonine kinase activityGO:0071902520.015
glucan metabolic processGO:0044042230.015
muscle structure developmentGO:0061061870.015
regulation of synaptic plasticityGO:0048167700.015
cellular response to molecule of bacterial originGO:0071219560.015
regulation of blood pressureGO:0008217830.015
positive regulation of neuron differentiationGO:00456661260.015
muscle system processGO:00030121150.015
carboxylic acid biosynthetic processGO:0046394830.015
cell cycleGO:00070491010.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
regulation of membrane potentialGO:00423911100.015
cellular amino acid biosynthetic processGO:0008652320.015
metal ion homeostasisGO:00550651860.015
positive regulation of response to external stimulusGO:0032103510.015
Human
positive regulation of immune system processGO:0002684900.015
ion homeostasisGO:00508012120.015
cellular carbohydrate metabolic processGO:0044262720.015
vesicle mediated transportGO:00161921810.015
protein maturationGO:0051604680.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
single organism organelle organizationGO:19025891800.014
heart morphogenesisGO:000300730.014
cofactor metabolic processGO:0051186950.014
regulation of synaptic transmissionGO:00508041410.014
negative regulation of protein metabolic processGO:00512481140.014
antigen receptor mediated signaling pathwayGO:005085110.014
negative regulation of catalytic activityGO:00430861030.014
developmental growthGO:00485891000.014
positive regulation of rna metabolic processGO:00512542030.014
sulfur compound metabolic processGO:0006790700.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
positive regulation of cell developmentGO:00107201760.014
nucleobase containing small molecule metabolic processGO:00550863160.014
cellular response to oxidative stressGO:0034599760.014
amide transportGO:00428861050.014
sensory organ developmentGO:0007423740.014
pteridine containing compound metabolic processGO:0042558140.014
nitrogen compound transportGO:00717052290.014
activation of protein kinase activityGO:0032147470.014
actin filament based processGO:0030029860.014
jnk cascadeGO:0007254280.014
positive regulation of growthGO:0045927550.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
small gtpase mediated signal transductionGO:0007264360.014
regulation of cell growthGO:0001558850.014
neuron developmentGO:00486662860.014
regulation of body fluid levelsGO:0050878900.014
regulation of dendrite developmentGO:0050773590.014
cellular response to biotic stimulusGO:0071216590.014
response to glucoseGO:00097491360.013
action potentialGO:0001508540.013
energy reserve metabolic processGO:0006112250.013
response to campGO:0051591910.013
positive regulation of apoptotic processGO:00430651540.013
reactive nitrogen species metabolic processGO:200105710.013
reactive oxygen species biosynthetic processGO:190340980.013
organic acid biosynthetic processGO:0016053830.013
negative regulation of proteolysisGO:0045861410.013
camera type eye developmentGO:0043010480.013
cytokine mediated signaling pathwayGO:0019221430.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
negative regulation of signal transductionGO:0009968830.013
ribonucleoside catabolic processGO:00424541260.013
mesoderm developmentGO:000749820.013
circulatory system developmentGO:00723591340.013
regulation of cellular component sizeGO:0032535510.013
cell growthGO:00160491040.013
regulation of cell morphogenesisGO:0022604770.013
coenzyme metabolic processGO:0006732860.013
aromatic compound catabolic processGO:00194391680.013
negative regulation of developmental processGO:00510931250.012
response to lipopolysaccharideGO:00324961910.012
regulation of cell cycleGO:0051726730.012
cellular response to reactive oxygen speciesGO:0034614550.012
purine ribonucleoside metabolic processGO:00461281680.012
transmission of nerve impulseGO:0019226420.012
brain developmentGO:00074202470.012
cellular macromolecular complex assemblyGO:0034622580.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
negative regulation of cellular biosynthetic processGO:00313271610.012
protein localization to organelleGO:0033365570.012
negative regulation of molecular functionGO:00440921330.012
embryonic pattern specificationGO:000988010.012
response to activityGO:0014823730.012
purine containing compound metabolic processGO:00725212530.012
response to corticosteroneGO:0051412400.012
autophagyGO:0006914190.012
Human
regulation of cd4 positive alpha beta t cell activationGO:200051410.012
asymmetric stem cell divisionGO:009872220.012
positive regulation of protein kinase activityGO:0045860730.012
sex differentiationGO:00075481130.012
lymphocyte mediated immunityGO:0002449140.012
intracellular protein transportGO:0006886790.012
neuronal action potentialGO:0019228350.012
regulation of protein secretionGO:0050708280.012
negative regulation of protein maturationGO:1903318470.012
positive regulation of jnk cascadeGO:0046330130.012
cation transmembrane transportGO:00986552630.012
gliogenesisGO:0042063930.012
regulation of cytokine biosynthetic processGO:004203530.012
leukocyte activationGO:0045321760.012
negative regulation of transcription dna templatedGO:00458921160.012
blood circulationGO:00080151830.012
anterior posterior pattern specificationGO:000995210.012
homeostatic processGO:00425923310.012
protein homooligomerizationGO:0051260910.012
regulation of protein kinase activityGO:00458591050.012
protein modification by small protein conjugationGO:0032446310.012
negative regulation of cellular protein metabolic processGO:00322691060.012
polysaccharide metabolic processGO:0005976250.012
regulation of protein processingGO:0070613500.012
regulation of adaptive immune responseGO:000281980.012
regulation of cellular catabolic processGO:00313291010.012
Human
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
regulation of actin filament based processGO:0032970420.011
purine nucleotide metabolic processGO:00061632290.011
wound healingGO:00420601220.011
ras protein signal transductionGO:0007265290.011
locomotionGO:00400112370.011
negative regulation of cell cycle phase transitionGO:190198840.011
cell activationGO:0001775970.011
negative regulation of innate immune responseGO:004582440.011
sensory perceptionGO:00076001010.011
hematopoietic progenitor cell differentiationGO:000224420.011
negative regulation of phosphate metabolic processGO:0045936800.011
nucleobase containing compound catabolic processGO:00346551520.011
angiogenesisGO:0001525530.011
blood vessel morphogenesisGO:0048514580.011
positive regulation of t cell mediated immunityGO:000271140.011
leukocyte differentiationGO:0002521300.011
regulation of system processGO:00440572080.011
multicellular organismal signalingGO:0035637440.011
negative regulation of cell communicationGO:00106481580.011
positive regulation of neurogenesisGO:00507691650.011
energy derivation by oxidation of organic compoundsGO:0015980460.011
response to tumor necrosis factorGO:0034612560.011
synaptic transmissionGO:00072682350.011
male sex differentiationGO:0046661640.011
hormone metabolic processGO:0042445690.011
regulation of defense responseGO:0031347680.011
nucleoside metabolic processGO:00091161790.011
inflammatory responseGO:00069541500.011
circulatory system processGO:00030131830.011
cellular polysaccharide metabolic processGO:0044264230.011
regulation of proteolysisGO:0030162660.011
alpha amino acid biosynthetic processGO:1901607230.011
nucleocytoplasmic transportGO:0006913480.011
blood vessel developmentGO:0001568690.011
negative regulation of protein processingGO:0010955470.011
regulation of cytokine productionGO:0001817560.010
positive regulation of secretionGO:00510471400.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
multicellular organismal homeostasisGO:0048871490.010
cation homeostasisGO:00550801950.010
peptide biosynthetic processGO:004304330.010
regulation of cell motilityGO:20001451310.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
organic cyclic compound catabolic processGO:19013611750.010
protein ubiquitinationGO:0016567280.010
positive regulation of neuron projection developmentGO:0010976990.010
peptidyl amino acid modificationGO:00181931260.010
negative regulation of phosphorus metabolic processGO:0010563800.010
synaptic growth at neuromuscular junctionGO:005112410.010
protein localization to nucleusGO:0034504390.010
regulation of immune effector processGO:0002697320.010

Sqstm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.030
disease of anatomical entityDOID:700.019
Human
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.013
inherited metabolic disorderDOID:65500.012