Rattus norvegicus

177 known processes

Cyp1a1

cytochrome P450, family 1, subfamily a, polypeptide 1

(Aliases: P450DX,Cypc45c,P1-450,P-450MC,AHH,AHRR,P450-C,CYP1,CP11,Cyp45c)

Cyp1a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
linoleic acid metabolic processGO:004365140.850
exogenous drug catabolic processGO:004273810.736
carboxylic acid metabolic processGO:00197522890.653
response to peptideGO:19016522920.576
Rat
halogenated hydrocarbon metabolic processGO:004219740.514
response to xenobiotic stimulusGO:0009410230.485
calcitriol biosynthetic process from calciolGO:003637820.479
alkaloid metabolic processGO:000982030.478
drug catabolic processGO:004273710.473
drug metabolic processGO:0017144110.436
Human
reproductive processGO:00224143720.419
monocarboxylic acid metabolic processGO:00327871520.417
chlorinated hydrocarbon metabolic processGO:004219640.411
arachidonic acid metabolic processGO:0019369200.407
oxoacid metabolic processGO:00434362900.372
response to corticosteroidGO:00319602350.370
response to peptide hormoneGO:00434342780.314
Rat
fatty acid metabolic processGO:0006631990.302
response to estradiolGO:00323551640.302
organic anion transportGO:00157111320.282
coumarin metabolic processGO:000980450.280
response to biotic stimulusGO:00096072260.265
cellular response to hormone stimulusGO:00328702470.246
Rat
lipid metabolic processGO:00066292830.225
secondary alcohol metabolic processGO:190265220.213
cellular response to xenobiotic stimulusGO:0071466190.207
multi organism reproductive processGO:00447032620.206
cellular lipid metabolic processGO:00442552080.189
lauric acid metabolic processGO:004825240.183
cellular response to organonitrogen compoundGO:00714171970.171
Rat
response to insulinGO:00328681330.170
organic hydroxy compound metabolic processGO:19016151150.164
Rat
xenobiotic metabolic processGO:0006805190.162
organic acid metabolic processGO:00060822920.161
long chain fatty acid metabolic processGO:0001676320.158
nicotine metabolic processGO:001893310.151
cellular response to endogenous stimulusGO:00714953770.145
Rat
response to glucocorticoidGO:00513842230.137
isoprenoid metabolic processGO:0006720450.136
cellular hormone metabolic processGO:0034754490.136
response to acid chemicalGO:00011012220.128
Rat
steroid metabolic processGO:0008202730.127
Rat
response to organophosphorusGO:00466831020.124
Rat
trichloroethylene metabolic processGO:001897910.120
cellular amino acid metabolic processGO:00065201070.118
multicellular organism reproductionGO:00325042330.114
single organism reproductive processGO:00447022970.110
response to estrogenGO:00436272320.104
epoxygenase p450 pathwayGO:001937310.102
agingGO:00075682410.101
vitamin d3 metabolic processGO:007064020.098
acylglycerol metabolic processGO:0006639210.097
response to nutrientGO:00075842480.094
unsaturated fatty acid metabolic processGO:0033559390.089
icosanoid metabolic processGO:0006690380.087
anion transportGO:00068201780.086
naphthalene metabolic processGO:001893120.084
fat soluble vitamin biosynthetic processGO:004236220.084
female pregnancyGO:00075651220.082
response to ethanolGO:00454711620.080
response to ddtGO:004668010.078
response to ketoneGO:19016541820.077
cellular catabolic processGO:00442482950.073
amino acid transportGO:0006865700.071
vitamin d metabolic processGO:004235940.070
regulation of lipid metabolic processGO:0019216680.069
Rat
growthGO:00400071650.069
response to metal ionGO:00100382530.067
biphenyl catabolic processGO:007098020.066
response to extracellular stimulusGO:00099913800.065
multi multicellular organism processGO:00447061380.065
response to nutrient levelsGO:00316673700.064
cellular response to oxygen containing compoundGO:19017013860.063
Rat
4 chlorobiphenyl metabolic processGO:001888010.060
reproductive structure developmentGO:00486081280.059
Rat
fluorene metabolic processGO:001891710.057
carboxylic acid transportGO:00469421150.057
negative regulation of innate immune responseGO:004582440.057
response to bacteriumGO:00096172000.056
vitamin d biosynthetic processGO:004236820.056
response to purine containing compoundGO:00140741260.055
Rat
response to inorganic substanceGO:00100353770.053
cellular alcohol biosynthetic processGO:004410820.053
tube developmentGO:0035295890.053
single organism biosynthetic processGO:00447113420.052
carboxylic acid biosynthetic processGO:0046394830.052
lipid localizationGO:0010876620.050
organ growthGO:0035265240.048
developmental process involved in reproductionGO:00030061590.048
Rat
xenobiotic catabolic processGO:004217870.048
lipid biosynthetic processGO:00086101280.047
regulation of growthGO:00400081050.046
reproductionGO:00000032450.046
terpenoid metabolic processGO:0006721370.044
small molecule biosynthetic processGO:00442831240.044
response to cesium ionGO:001016420.044
diterpenoid metabolic processGO:0016101330.044
monocarboxylic acid transportGO:0015718520.043
multicellular organismal reproductive processGO:00486092330.043
sexual reproductionGO:00199531480.043
Rat
development of primary sexual characteristicsGO:00451371070.043
Rat
organic acid transportGO:00158491160.042
naphthalene containing compound metabolic processGO:009042020.041
muscle structure developmentGO:0061061870.041
gland developmentGO:00487321550.041
response to sulfur dioxideGO:001047730.040
cation transmembrane transportGO:00986552630.040
organic hydroxy compound biosynthetic processGO:1901617510.040
anatomical structure morphogenesisGO:00096532980.040
regulation of multicellular organismal developmentGO:20000263760.040
catabolic processGO:00090563510.040
phenol containing compound metabolic processGO:0018958300.038
Rat
cellular response to stressGO:00335542690.037
vitamin biosynthetic processGO:000911030.037
neuron projection developmentGO:00311752730.036
brain developmentGO:00074202470.036
Rat
response to lipopolysaccharideGO:00324961910.035
intracellular signal transductionGO:00355563140.034
response to fungicideGO:0060992200.034
Rat
positive regulation of signalingGO:00230562700.034
fatty acid derivative metabolic processGO:1901568380.034
regulation of hormone levelsGO:00108171870.034
circulatory system processGO:00030131830.034
positive regulation of biosynthetic processGO:00098913190.033
Rat
regulation of intracellular signal transductionGO:19025312180.033
regulation of cellular amino acid metabolic processGO:000652120.033
reproductive system developmentGO:00614581280.032
Rat
glycerolipid metabolic processGO:0046486670.032
negative regulation of macromolecule metabolic processGO:00106052600.032
positive regulation of cell communicationGO:00106472710.032
response to oxidative stressGO:00069791860.032
response to nicotineGO:0035094510.032
enzyme linked receptor protein signaling pathwayGO:00071671160.032
single organism behaviorGO:00447081300.031
regulation of molecular functionGO:00650093980.031
response to other organismGO:00517072200.031
response to reactive oxygen speciesGO:00003021200.031
response to campGO:0051591910.030
Rat
tetrahydrofolate metabolic processGO:004665390.030
oxidation reduction processGO:00551143040.029
organic acid biosynthetic processGO:0016053830.029
developmental inductionGO:003112820.029
positive regulation of molecular functionGO:00440932300.028
negative regulation of protein metabolic processGO:00512481140.028
lipid transportGO:0006869610.028
folic acid containing compound metabolic processGO:0006760100.028
regulation of cellular catabolic processGO:00313291010.028
toxin catabolic processGO:000940710.027
regulation of cell growthGO:0001558850.027
rna biosynthetic processGO:00327743800.027
regulation of rna biosynthetic processGO:20011413810.027
developmental growthGO:00485891000.026
alcohol metabolic processGO:0006066770.026
cell growthGO:00160491040.026
regulation of phosphorylationGO:00423252480.026
ovulation cycleGO:0042698670.026
cellular response to organic cyclic compoundGO:00714072020.026
Human Zebrafish
cellular response to peptideGO:19016531330.026
Rat
regulation of developmental growthGO:0048638450.026
regulation of cellular ketone metabolic processGO:0010565270.026
negative regulation of collagen biosynthetic processGO:003296640.025
hepaticobiliary system developmentGO:0061008900.025
rhythmic processGO:00485111560.025
phenylpropanoid catabolic processGO:004627130.025
membrane organizationGO:0061024940.025
regulation of fat cell proliferationGO:007034410.025
sex differentiationGO:00075481130.024
Rat
regulation of phosphate metabolic processGO:00192203490.024
response to radiationGO:00093141370.023
Rat
regulation of blood circulationGO:19035221100.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
blood circulationGO:00080151830.022
neutral lipid metabolic processGO:0006638210.022
regulation of cellular protein metabolic processGO:00322682670.022
triglyceride metabolic processGO:0006641210.022
organic hydroxy compound transportGO:0015850770.022
transmembrane transportGO:00550854120.022
regulation of neuron deathGO:19012141150.022
development of primary female sexual characteristicsGO:0046545560.022
regulation of cellular component organizationGO:00511283680.022
organophosphate metabolic processGO:00196373700.022
positive regulation of nitrogen compound metabolic processGO:00511733340.022
organonitrogen compound biosynthetic processGO:19015661670.022
phenylpropanoid metabolic processGO:000969850.022
positive regulation of multicellular organismal processGO:00512403870.022
4 nitrophenol metabolic processGO:001896010.021
fat cell proliferationGO:007034120.021
coumarin catabolic processGO:004622630.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
cellular response to glucocorticoid stimulusGO:0071385680.021
cellular modified amino acid metabolic processGO:0006575610.021
cellular response to growth factor stimulusGO:00713631620.021
female gonad developmentGO:0008585530.020
positive regulation of catalytic activityGO:00430851840.020
epithelium developmentGO:0060429960.020
response to amino acidGO:0043200750.020
response to growth factorGO:00708481890.020
bile acid and bile salt transportGO:0015721120.020
response to toxic substanceGO:00096361330.020
response to transition metal nanoparticleGO:19902671220.019
skeletal muscle cell differentiationGO:003591420.019
regulation of sodium ion transmembrane transporter activityGO:200064940.019
negative regulation of organ growthGO:004662130.019
regulation of neurogenesisGO:00507672470.019
response to external biotic stimulusGO:00432072210.019
regulation of cell proliferationGO:00421273590.019
multicellular organism growthGO:003526410.019
cell projection organizationGO:00300303020.019
response to alkaloidGO:00432791320.019
response to woundingGO:00096112540.019
response to fibroblast growth factorGO:0071774290.019
regulation of system processGO:00440572080.019
small gtpase mediated signal transductionGO:0007264360.019
cellular ketone metabolic processGO:0042180510.018
Rat
negative regulation of cardiac muscle tissue developmentGO:005502630.018
positive regulation of behavioral fear responseGO:200098730.018
positive regulation of phosphorus metabolic processGO:00105622620.018
female sex differentiationGO:0046660590.018
cellular amine metabolic processGO:0044106380.018
cell communication by chemical couplingGO:001064320.018
response to gonadotropinGO:0034698340.018
Rat
regulation of signal transductionGO:00099663180.018
organ inductionGO:000175910.018
neuron developmentGO:00486662860.018
response to vitaminGO:00332731310.018
cellular response to steroid hormone stimulusGO:0071383930.018
single organism catabolic processGO:00447122830.017
negative regulation of metabolic processGO:00098923310.017
insecticide metabolic processGO:001714340.017
benzene containing compound metabolic processGO:0042537220.017
Rat
cellular response to vitamin eGO:007130630.017
hormone catabolic processGO:004244720.017
secondary metabolite catabolic processGO:009048710.017
sterol homeostasisGO:005509230.017
regulation of transcription dna templatedGO:00063553740.017
male gonad developmentGO:0008584590.017
Rat
regulation of catabolic processGO:00098941130.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
response to ionizing radiationGO:0010212590.017
Rat
acid secretionGO:0046717480.017
regulation of transferase activityGO:00513381230.017
regulation of cellular amine metabolic processGO:003323880.017
cellular component movementGO:00069282480.017
ion transmembrane transportGO:00342203650.017
pyridine containing compound metabolic processGO:0072524320.017
inorganic cation transmembrane transportGO:00986622020.016
positive regulation of growthGO:0045927550.016
response to corticosteroneGO:0051412400.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
rna metabolic processGO:00160704060.016
drug transmembrane transportGO:0006855130.016
response to carbohydrateGO:00097431830.016
regulation of protein metabolic processGO:00512462890.016
coronary vasculature morphogenesisGO:006097730.016
regulation of body fluid levelsGO:0050878900.016
cholesterol homeostasisGO:004263230.016
central nervous system developmentGO:00074173110.015
Rat
amide transportGO:00428861050.015
neuron deathGO:00709971270.015
nucleic acid templated transcriptionGO:00976593790.015
positive regulation of response to stimulusGO:00485842850.015
alcohol biosynthetic processGO:0046165380.015
positive regulation of nucleobase containing compound metabolic processGO:00459353190.015
gonad developmentGO:00084061040.015
Rat
cellular response to alcoholGO:0097306870.015
regulation of blood pressureGO:0008217830.015
amine metabolic processGO:0009308380.015
Mouse
response to transforming growth factor betaGO:0071559460.015
negative regulation of cell communicationGO:00106481580.015
negative regulation of molecular functionGO:00440921330.015
regulation of cell developmentGO:00602842630.015
positive regulation of phosphate metabolic processGO:00459372620.014
neuromuscular processGO:005090520.014
cellular response to corticosteroid stimulusGO:0071384690.014
cellular response to oxidative stressGO:0034599760.014
nucleobase containing small molecule metabolic processGO:00550863160.014
negative regulation of cellular biosynthetic processGO:00313271610.014
neuron differentiationGO:00301823680.014
gamete generationGO:00072761240.014
Rat
c21 steroid hormone metabolic processGO:0008207140.014
Rat
regulation of rna metabolic processGO:00512523910.014
regulation of cell differentiationGO:00455953200.014
peptide biosynthetic processGO:004304330.014
negative regulation of catalytic activityGO:00430861030.014
positive regulation of cell proliferationGO:00082842490.014
cellular response to peptide hormone stimulusGO:00713751200.014
Rat
regulation of cell projection organizationGO:00313441750.014
regulation of cytokine biosynthetic processGO:004203530.014
secretionGO:00469033070.014
lipid storageGO:001991510.014
regulation of nervous system developmentGO:00519602640.014
negative regulation of cell proliferationGO:00082851190.014
positive regulation of secretion by cellGO:19035321280.014
neurological system processGO:00508772190.014
positive regulation of fat cell proliferationGO:007034610.014
positive regulation of developmental processGO:00510942830.013
response to retinoic acidGO:0032526630.013
Rat
transcription from rna polymerase ii promoterGO:00063662520.013
sulfationGO:005192320.013
negative regulation of biosynthetic processGO:00098901680.013
digestive tract developmentGO:0048565390.013
grooming behaviorGO:000762540.013
regulation of neuron differentiationGO:00456642080.013
regulation of vascular smooth muscle contractionGO:000305630.013
progesterone biosynthetic processGO:000670130.013
positive regulation of cellular amine metabolic processGO:003324030.013
transcription dna templatedGO:00063513770.013
tissue developmentGO:00098882520.012
regulation of phosphorus metabolic processGO:00511743490.012
macromolecular complex assemblyGO:00650032730.012
ras protein signal transductionGO:0007265290.012
programmed cell deathGO:00125013920.012
negative regulation of cell developmentGO:0010721820.012
positive regulation of cellular biosynthetic processGO:00313282950.012
Rat
regenerationGO:00310991630.012
response to vitamin aGO:0033189360.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
negative regulation of cellular metabolic processGO:00313242810.012
negative regulation of cardiac muscle tissue growthGO:005502230.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
regulation of brown fat cell proliferationGO:007034710.012
positive regulation of brown fat cell proliferationGO:007034910.012
behavioral response to ethanolGO:004814910.012
regulation of tube sizeGO:0035150890.012
cellular modified amino acid biosynthetic processGO:0042398180.012
negative regulation of intracellular signal transductionGO:1902532380.012
cardiac muscle tissue growthGO:0055017200.012
organophosphate biosynthetic processGO:00904071430.012
defense response to gram negative bacteriumGO:005082930.012
regulation of organ formationGO:000315620.012
dephosphorylationGO:0016311980.012
vascular process in circulatory systemGO:0003018960.012
response to monosaccharideGO:00342841590.011
regulation of catalytic activityGO:00507903040.011
cytokine biosynthetic processGO:004208930.011
response to lithium ionGO:0010226280.011
secondary metabolic processGO:0019748150.011
negative regulation of multicellular organismal processGO:00512412030.011
striated muscle tissue developmentGO:0014706580.011
alpha amino acid metabolic processGO:1901605710.011
positive regulation of phagocytosis engulfmentGO:006010040.011
cellular response to campGO:0071320260.011
positive regulation of cell differentiationGO:00455972170.011
specification of organ identityGO:001009220.011
response to cytokineGO:00340972150.011
Rat
proteolysisGO:00065081750.011
regulation of cellular extravasationGO:000269120.011
organ formationGO:004864530.011
brown fat cell proliferationGO:007034220.011
embryo developmentGO:0009790490.011
cellular amino acid biosynthetic processGO:0008652320.011
cardiac muscle tissue developmentGO:0048738260.011
sodium ion transmembrane transportGO:0035725670.011
negative regulation of cell cycle phase transitionGO:190198840.011
toxin metabolic processGO:000940490.011
cellular response to nitrogen compoundGO:19016992100.011
Rat
cellular response to extracellular stimulusGO:0031668730.011
cell cell signaling involved in cell fate commitmentGO:004516820.010
response to cadmium ionGO:0046686350.010
heart developmentGO:0007507720.010
regulation of fat cell differentiationGO:004559830.010
carbohydrate catabolic processGO:0016052400.010
positive regulation of renin secretion into blood streamGO:190013510.010
cellular homeostasisGO:00197252520.010
response to hexoseGO:00097461440.010
cellular response to nutrient levelsGO:0031669600.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
positive regulation of lipid metabolic processGO:0045834330.010
Rat

Cyp1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
artery diseaseDOID:005082800.078
vascular diseaseDOID:17800.078
disease of anatomical entityDOID:700.078
essential hypertensionDOID:1082500.078
cardiovascular system diseaseDOID:128700.078
hypertensionDOID:1076300.078
nervous system diseaseDOID:86300.013
disease of metabolismDOID:001466700.013
congenital adrenal hyperplasiaDOID:005081100.013
lipid metabolism disorderDOID:314600.013
inherited metabolic disorderDOID:65500.013
steroid inherited metabolic disorderDOID:170100.013