Rattus norvegicus

0 known processes

Pde6a

phosphodiesterase 6A, cGMP-specific, rod, alpha

Pde6a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.088
response to nutrientGO:00075842480.077
macromolecule localizationGO:00330362520.069
Rat
response to nutrient levelsGO:00316673700.067
tissue developmentGO:00098882520.065
Rat
response to inorganic substanceGO:00100353770.063
intracellular signal transductionGO:00355563140.060
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.057
reproductive processGO:00224143720.055
response to decreased oxygen levelsGO:00362932370.054
Rat
rna metabolic processGO:00160704060.053
cellular lipid metabolic processGO:00442552080.051
response to oxygen levelsGO:00704822650.050
Rat
agingGO:00075682410.049
regulation of rna metabolic processGO:00512523910.048
multicellular organismal reproductive processGO:00486092330.047
homeostatic processGO:00425923310.046
Human
cellular response to oxygen containing compoundGO:19017013860.046
ion homeostasisGO:00508012120.046
Human
divalent inorganic cation homeostasisGO:00725071650.045
Human
anatomical structure morphogenesisGO:00096532980.043
positive regulation of molecular functionGO:00440932300.043
response to metal ionGO:00100382530.043
regulation of blood circulationGO:19035221100.042
Rat
response to hypoxiaGO:00016662310.042
Rat
negative regulation of cellular metabolic processGO:00313242810.041
Rat
regulation of secretion by cellGO:19035302080.040
cellular response to stressGO:00335542690.039
regulation of transcription dna templatedGO:00063553740.038
lipid metabolic processGO:00066292830.038
amine metabolic processGO:0009308380.038
organelle organizationGO:00069962660.037
Rat
response to extracellular stimulusGO:00099913800.036
cellular metal ion homeostasisGO:00068751720.036
Human
cellular component assemblyGO:00226073600.036
sodium ion transportGO:0006814820.036
circulatory system processGO:00030131830.036
Rat
epithelial cell differentiationGO:0030855710.036
Rat
ion transmembrane transportGO:00342203650.035
response to corticosteroidGO:00319602350.035
organophosphate metabolic processGO:00196373700.035
Human Rat
chemical homeostasisGO:00488782920.035
Human
regulation of molecular functionGO:00650093980.033
single organism reproductive processGO:00447022970.033
oxoacid metabolic processGO:00434362900.033
cellular ion homeostasisGO:00068731840.033
Human
developmental process involved in reproductionGO:00030061590.032
response to estrogenGO:00436272320.032
multicellular organism reproductionGO:00325042330.032
cellular response to lipidGO:00713962010.032
single organism biosynthetic processGO:00447113420.032
Rat
cellular calcium ion homeostasisGO:00068741600.032
Human
multi organism reproductive processGO:00447032620.031
negative regulation of gene expressionGO:00106291990.031
anion transportGO:00068201780.031
metal ion homeostasisGO:00550651860.030
Human
development of primary sexual characteristicsGO:00451371070.030
sexual reproductionGO:00199531480.030
regulation of cell proliferationGO:00421273590.030
regulation of signal transductionGO:00099663180.030
cellular component morphogenesisGO:00329891550.029
regulation of nucleic acid templated transcriptionGO:19035063800.029
transcription dna templatedGO:00063513770.029
nucleic acid templated transcriptionGO:00976593790.029
positive regulation of cellular biosynthetic processGO:00313282950.028
response to glucocorticoidGO:00513842230.028
rna biosynthetic processGO:00327743800.028
reproductionGO:00000032450.028
single organism intracellular transportGO:19025821660.028
Rat
metal ion transportGO:00300012890.028
carboxylic acid metabolic processGO:00197522890.028
programmed cell deathGO:00125013920.027
Rat
inorganic ion transmembrane transportGO:00986602290.027
cellular divalent inorganic cation homeostasisGO:00725031620.027
Human
cellular chemical homeostasisGO:00550822470.027
Human
organic acid metabolic processGO:00060822920.027
macromolecular complex subunit organizationGO:00439333390.027
negative regulation of metabolic processGO:00098923310.026
Rat
response to radiationGO:00093141370.026
negative regulation of biosynthetic processGO:00098901680.026
Rat
response to peptideGO:19016522920.026
cellular amino acid metabolic processGO:00065201070.026
regulation of cellular localizationGO:00603412630.026
reproductive structure developmentGO:00486081280.026
regulation of protein metabolic processGO:00512462890.026
blood circulationGO:00080151830.026
Rat
cellular amine metabolic processGO:0044106380.025
calcium ion homeostasisGO:00550741620.025
Human
negative regulation of nitrogen compound metabolic processGO:00511721610.025
Rat
positive regulation of biosynthetic processGO:00098913190.025
protein phosphorylationGO:00064683450.025
apoptotic processGO:00069153810.025
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.025
intracellular transportGO:00469071850.025
Rat
gonad developmentGO:00084061040.024
regulation of protein phosphorylationGO:00019321830.024
positive regulation of response to stimulusGO:00485842850.024
Rat
regulation of programmed cell deathGO:00430673410.024
Rat
cation homeostasisGO:00550801950.024
Human
negative regulation of macromolecule metabolic processGO:00106052600.024
negative regulation of programmed cell deathGO:00430691830.024
response to woundingGO:00096112540.024
Rat
epithelium developmentGO:0060429960.024
Rat
reproductive system developmentGO:00614581280.024
response to toxic substanceGO:00096361330.023
carbohydrate derivative metabolic processGO:19011353460.023
Human Rat
regulation of secretionGO:00510462240.023
regulation of cell differentiationGO:00455953200.023
positive regulation of gene expressionGO:00106282440.023
positive regulation of signalingGO:00230562700.023
response to biotic stimulusGO:00096072260.023
Rat
response to vitaminGO:00332731310.023
regulation of cellular protein metabolic processGO:00322682670.022
cellular component biogenesisGO:00440853680.022
negative regulation of cell deathGO:00605482290.022
response to cytokineGO:00340972150.022
cellular response to organic cyclic compoundGO:00714072020.022
positive regulation of cell communicationGO:00106472710.022
cellular homeostasisGO:00197252520.022
Human
protein transportGO:00150311320.021
Rat
regulation of apoptotic processGO:00429813350.021
Rat
regulation of catalytic activityGO:00507903040.021
regulation of system processGO:00440572080.021
Rat
positive regulation of phosphorus metabolic processGO:00105622620.021
cellular cation homeostasisGO:00300031800.021
Human
protein localizationGO:00081041910.021
Rat
macromolecular complex assemblyGO:00650032730.021
regulation of cellular component movementGO:00512701500.021
regulation of blood vessel sizeGO:0050880890.020
Rat
regulation of phosphorus metabolic processGO:00511743490.020
Rat
heart morphogenesisGO:000300730.020
cellular component movementGO:00069282480.020
gamete generationGO:00072761240.020
positive regulation of cellular protein metabolic processGO:00322701670.020
transcription from rna polymerase ii promoterGO:00063662520.020
purine ribonucleotide metabolic processGO:00091502270.020
Human Rat
central nervous system developmentGO:00074173110.020
regulation of cellular ketone metabolic processGO:0010565270.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
secretionGO:00469033070.020
cation transportGO:00068123820.019
positive regulation of protein metabolic processGO:00512471780.019
nitrogen compound transportGO:00717052290.019
positive regulation of rna biosynthetic processGO:19026801970.019
regulation of cellular amino acid metabolic processGO:000652120.019
axis specificationGO:000979840.019
response to growth factorGO:00708481890.019
single organism organelle organizationGO:19025891800.019
negative regulation of apoptotic processGO:00430661810.019
protein complex assemblyGO:00064612630.019
positive regulation of synaptic transmissionGO:0050806620.019
inorganic cation transmembrane transportGO:00986622020.019
regulation of cellular component organizationGO:00511283680.019
response to reactive oxygen speciesGO:00003021200.019
response to peptide hormoneGO:00434342780.019
response to transition metal nanoparticleGO:19902671220.018
positive regulation of catalytic activityGO:00430851840.018
response to other organismGO:00517072200.018
Rat
regulation of phosphate metabolic processGO:00192203490.018
Rat
positive regulation of protein modification processGO:00314011420.018
cellular protein localizationGO:00346131220.018
Rat
neuron differentiationGO:00301823680.018
positive regulation of multicellular organismal processGO:00512403870.018
Rat
brain developmentGO:00074202470.018
regulation of nucleotide metabolic processGO:00061401170.018
Rat
cellular response to oxidative stressGO:0034599760.018
regulation of rna biosynthetic processGO:20011413810.018
positive regulation of rna metabolic processGO:00512542030.017
cellular response to nitrogen compoundGO:19016992100.017
negative regulation of rna biosynthetic processGO:19026791180.017
regulation of cellular amine metabolic processGO:003323880.017
monovalent inorganic cation transportGO:00156721720.017
ribose phosphate metabolic processGO:00196932350.017
Human Rat
protein complex biogenesisGO:00702712630.017
cellular response to abiotic stimulusGO:0071214850.017
cellular response to external stimulusGO:00714961180.017
g protein coupled receptor signaling pathwayGO:00071862420.017
positive regulation of cellular component organizationGO:00511302000.017
positive regulation of secretion by cellGO:19035321280.017
regulation of multicellular organismal developmentGO:20000263760.017
protein oligomerizationGO:00512591910.017
lipid transportGO:0006869610.017
neurological system processGO:00508772190.017
Rat
sodium ion transmembrane transportGO:0035725670.016
transmission of nerve impulseGO:0019226420.016
regulation of hormone levelsGO:00108171870.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
Rat
vesicle mediated transportGO:00161921810.016
regulation of protein modification processGO:00313991940.016
response to oxidative stressGO:00069791860.016
male sex differentiationGO:0046661640.016
synaptic transmissionGO:00072682350.016
sex differentiationGO:00075481130.016
neuron projection developmentGO:00311752730.016
cellular response to endogenous stimulusGO:00714953770.016
positive regulation of transportGO:00510502450.016
positive regulation of cell deathGO:00109421840.015
Rat
eye morphogenesisGO:004859240.015
cellular response to growth factor stimulusGO:00713631620.015
dephosphorylationGO:0016311980.015
regulation of cell migrationGO:00303341280.015
purine containing compound biosynthetic processGO:0072522850.015
Rat
cation transmembrane transportGO:00986552630.015
response to ketoneGO:19016541820.015
Rat
response to ethanolGO:00454711620.015
muscle cell proliferationGO:0033002840.015
secretion by cellGO:00329402480.015
neuronal action potentialGO:0019228350.015
positive regulation of cell proliferationGO:00082842490.015
regulation of cell developmentGO:00602842630.015
spermatogenesisGO:0007283990.015
positive regulation of cellular amine metabolic processGO:003324030.015
regulation of anatomical structure sizeGO:00900661350.015
Rat
cyclic nucleotide metabolic processGO:0009187800.015
Rat
response to amino acidGO:0043200750.015
cellular response to organonitrogen compoundGO:00714171970.015
urogenital system developmentGO:0001655780.014
positive regulation of developmental processGO:00510942830.014
regulation of body fluid levelsGO:0050878900.014
hormone transportGO:00099141210.014
hormone secretionGO:00468791150.014
male gamete generationGO:0048232990.014
cell projection organizationGO:00300303020.014
negative regulation of cell communicationGO:00106481580.014
membrane organizationGO:0061024940.014
positive regulation of cell migrationGO:0030335960.014
sensory organ developmentGO:0007423740.014
reactive oxygen species metabolic processGO:0072593370.013
cell morphogenesisGO:00009021420.013
multicellular organismal signalingGO:0035637440.013
gland developmentGO:00487321550.013
monocarboxylic acid transportGO:0015718520.013
positive regulation of transcription dna templatedGO:00458931970.013
cellular response to steroid hormone stimulusGO:0071383930.013
negative regulation of response to stimulusGO:00485851550.013
male gonad developmentGO:0008584590.013
nucleotide biosynthetic processGO:0009165980.013
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
neuron developmentGO:00486662860.013
negative regulation of organ growthGO:004662130.013
camp biosynthetic processGO:0006171470.013
Rat
action potentialGO:0001508540.013
negative regulation of secretionGO:0051048820.013
organic acid biosynthetic processGO:0016053830.013
signal releaseGO:00230611450.013
regulation of peptide transportGO:0090087870.013
regulation of response to stressGO:00801341260.013
Rat
camera type eye morphogenesisGO:004859320.013
negative regulation of cellular protein metabolic processGO:00322691060.013
cellular catabolic processGO:00442482950.013
Rat
divalent inorganic cation transportGO:00725111340.013
positive regulation of secretionGO:00510471400.013
olfactory behaviorGO:004204820.013
single organism membrane organizationGO:0044802740.013
regulation of establishment of protein localizationGO:0070201690.012
signal transduction by phosphorylationGO:00230141440.012
organic anion transportGO:00157111320.012
carbohydrate derivative biosynthetic processGO:19011371240.012
Rat
response to acid chemicalGO:00011012220.012
gliogenesisGO:0042063930.012
circulatory system developmentGO:00723591340.012
actin filament based processGO:0030029860.012
protein homooligomerizationGO:0051260910.012
nucleotide metabolic processGO:00091172790.012
Human Rat
organ regenerationGO:00311001010.012
establishment of protein localizationGO:00451841410.012
Rat
cellular ketone metabolic processGO:0042180510.012
response to lipopolysaccharideGO:00324961910.012
Rat
cellular response to cytokine stimulusGO:00713451270.012
cardiovascular system developmentGO:00723581340.012
response to interleukin 1GO:0070555550.012
positive regulation of cellular component movementGO:00512721020.012
purine nucleotide metabolic processGO:00061632290.012
Human Rat
organic hydroxy compound metabolic processGO:19016151150.012
positive regulation of phosphate metabolic processGO:00459372620.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
purine nucleotide biosynthetic processGO:0006164830.012
Rat
negative regulation of catalytic activityGO:00430861030.012
cell cell signalingGO:00072673350.012
nucleobase containing small molecule metabolic processGO:00550863160.012
Human Rat
purine ribonucleotide biosynthetic processGO:0009152810.012
Rat
adult locomotory behaviorGO:000834440.012
organic hydroxy compound transportGO:0015850770.012
cellular hormone metabolic processGO:0034754490.012
response to hydrogen peroxideGO:0042542890.012
regulation of membrane potentialGO:00423911100.012
multi multicellular organism processGO:00447061380.011
regulation of phosphorylationGO:00423252480.011
cyclic purine nucleotide metabolic processGO:0052652620.011
Rat
negative regulation of protein metabolic processGO:00512481140.011
peptide transportGO:0015833970.011
female pregnancyGO:00075651220.011
heart contractionGO:0060047570.011
Rat
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
localization of cellGO:00516742020.011
response to zinc ionGO:0010043390.011
regulation of smooth muscle cell proliferationGO:0048660750.011
camera type eye developmentGO:0043010480.011
proteolysisGO:00065081750.011
phototransduction visible lightGO:000760320.011
regulation of ion transportGO:00432692450.011
regulation of intracellular signal transductionGO:19025312180.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
cellular response to peptideGO:19016531330.011
chemosensory behaviorGO:000763520.011
cell type specific apoptotic processGO:00972851340.011
response to alkaloidGO:00432791320.011
nucleoside phosphate metabolic processGO:00067532830.011
Human Rat
response to external biotic stimulusGO:00432072210.011
Rat
monocarboxylic acid metabolic processGO:00327871520.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
positive regulation of phosphorylationGO:00423271770.011
cellular response to alcoholGO:0097306870.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
response to glucoseGO:00097491360.011
regulation of protein kinase activityGO:00458591050.011
single organism behaviorGO:00447081300.011
Rat
meiotic cell cycle processGO:190304630.011
organophosphate biosynthetic processGO:00904071430.011
Rat
response to fatty acidGO:0070542650.011
organ morphogenesisGO:0009887750.011
peptide secretionGO:0002790860.011
small gtpase mediated signal transductionGO:0007264360.011
response to carbohydrateGO:00097431830.011
retina morphogenesis in camera type eyeGO:006004210.011
positive regulation of signal transductionGO:00099671750.011
lipid localizationGO:0010876620.011
response to mechanical stimulusGO:00096121340.010
detection of visible lightGO:000958430.010
regulation of peptide secretionGO:0002791820.010
positive regulation of cell differentiationGO:00455972170.010
bmp signaling pathwayGO:003050940.010
regulation of cell motilityGO:20001451310.010
purine containing compound metabolic processGO:00725212530.010
Human Rat
sequestering of metal ionGO:005123890.010
lipid biosynthetic processGO:00086101280.010
response to monosaccharideGO:00342841590.010
anterior posterior pattern specificationGO:000995210.010
glial cell differentiationGO:0010001650.010
regulation of metal ion transportGO:00109591180.010
regulation of protein localizationGO:0032880810.010
alcohol metabolic processGO:0006066770.010
negative regulation of signalingGO:00230571570.010
chromosome segregationGO:000705920.010
regulation of mrna splicing via spliceosomeGO:004802430.010

Pde6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.074
Human
sensory system diseaseDOID:005015500.074
Human
nervous system diseaseDOID:86300.074
Human
eye and adnexa diseaseDOID:149200.074
Human
eye diseaseDOID:561400.035
Human
retinal diseaseDOID:567900.028
Human
retinal degenerationDOID:846600.026
Human
retinitis pigmentosaDOID:1058400.026
Human
musculoskeletal system diseaseDOID:1700.018