Rattus norvegicus

67 known processes

Hprt1

hypoxanthine phosphoribosyltransferase 1

(Aliases: MGC112554,Hgprtase,Hprt)

Hprt1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna metabolic processGO:00512523910.449
cellular response to peptideGO:19016531330.415
regulation of nucleic acid templated transcriptionGO:19035063800.311
inorganic ion transmembrane transportGO:00986602290.308
regulation of transcription dna templatedGO:00063553740.302
apoptotic processGO:00069153810.246
transcription dna templatedGO:00063513770.228
single organism organelle organizationGO:19025891800.220
macromolecular complex assemblyGO:00650032730.209
Human
nucleic acid templated transcriptionGO:00976593790.202
macromolecular complex subunit organizationGO:00439333390.202
Human
regulation of rna biosynthetic processGO:20011413810.197
regulation of programmed cell deathGO:00430673410.193
rna metabolic processGO:00160704060.177
reproductionGO:00000032450.158
organic acid metabolic processGO:00060822920.157
protein complex subunit organizationGO:00718223020.152
Human
actin filament based processGO:0030029860.151
response to insulinGO:00328681330.147
programmed cell deathGO:00125013920.140
regulation of proteasomal protein catabolic processGO:006113640.140
response to nutrient levelsGO:00316673700.136
transcription from rna polymerase ii promoterGO:00063662520.136
response to peptide hormoneGO:00434342780.131
reproductive processGO:00224143720.124
protein complex biogenesisGO:00702712630.121
Human
cellular response to endogenous stimulusGO:00714953770.114
response to peptideGO:19016522920.110
single organism biosynthetic processGO:00447113420.108
Human
protein sumoylationGO:001692540.108
ion transmembrane transportGO:00342203650.105
response to hypoxiaGO:00016662310.104
negative regulation of metabolic processGO:00098923310.104
response to extracellular stimulusGO:00099913800.101
cellular component assemblyGO:00226073600.101
Human
single organism reproductive processGO:00447022970.098
negative regulation of nucleic acid templated transcriptionGO:19035071170.095
cellular component morphogenesisGO:00329891550.093
nucleoside monophosphate metabolic processGO:0009123930.091
Human
organelle organizationGO:00069962660.089
proteasomal protein catabolic processGO:001049880.086
regulation of protein metabolic processGO:00512462890.084
regulation of protein catabolic processGO:0042176160.083
cellular protein catabolic processGO:0044257190.082
response to decreased oxygen levelsGO:00362932370.082
macromolecule catabolic processGO:0009057580.081
regulation of transcription from rna polymerase ii promoterGO:00063572340.080
response to oxygen levelsGO:00704822650.079
regulation of apoptotic processGO:00429813350.073
cation transmembrane transportGO:00986552630.071
regulation of phosphorus metabolic processGO:00511743490.071
actin cytoskeleton organizationGO:0030036730.069
proteolysis involved in cellular protein catabolic processGO:0051603190.069
cellular response to xenobiotic stimulusGO:0071466190.067
negative regulation of cellular biosynthetic processGO:00313271610.066
cellular response to stressGO:00335542690.065
cellular component biogenesisGO:00440853680.064
Human
cell projection morphogenesisGO:00488581230.062
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.062
protein complex assemblyGO:00064612630.062
Human
regulation of transmembrane transportGO:00347621220.061
negative regulation of apoptotic processGO:00430661810.059
sexual reproductionGO:00199531480.057
regulation of cellular component organizationGO:00511283680.057
heart contractionGO:0060047570.057
inorganic cation transmembrane transportGO:00986622020.057
positive regulation of macromolecule biosynthetic processGO:00105572470.056
biological adhesionGO:00226101100.056
organic substance catabolic processGO:19015753160.055
Human
rna biosynthetic processGO:00327743800.055
carboxylic acid metabolic processGO:00197522890.055
regulation of cell proliferationGO:00421273590.055
blood circulationGO:00080151830.054
metal ion transportGO:00300012890.053
er associated ubiquitin dependent protein catabolic processGO:003043310.052
regulation of phosphorylationGO:00423252480.052
oxoacid metabolic processGO:00434362900.049
regulation of response to stressGO:00801341260.048
negative regulation of programmed cell deathGO:00430691830.048
cellular response to insulin stimulusGO:0032869810.047
neuron projection developmentGO:00311752730.047
dna damage response detection of dna damageGO:004276920.047
cellular response to hormone stimulusGO:00328702470.047
regulation of ion transportGO:00432692450.047
protein catabolic processGO:0030163300.047
proteolysisGO:00065081750.047
regulation of cardiac muscle contractionGO:0055117170.046
cellular amino acid metabolic processGO:00065201070.046
neuron developmentGO:00486662860.046
organonitrogen compound biosynthetic processGO:19015661670.046
Human
regenerationGO:00310991630.046
amine metabolic processGO:0009308380.045
Human
neuron apoptotic processGO:0051402880.045
negative regulation of cell deathGO:00605482290.045
heart processGO:0003015570.044
multicellular organism reproductionGO:00325042330.044
regulation of neuron deathGO:19012141150.044
cation transportGO:00068123820.044
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.043
regulation of calcium ion transmembrane transporter activityGO:1901019170.043
cellular catabolic processGO:00442482950.043
Human
protein modification by small protein conjugationGO:0032446310.043
negative regulation of molecular functionGO:00440921330.042
regulation of protein phosphorylationGO:00019321830.042
negative regulation of rna metabolic processGO:00512531230.042
divalent metal ion transportGO:00708381320.042
regulation of cell differentiationGO:00455953200.042
internal peptidyl lysine acetylationGO:001839390.041
mitochondrion organizationGO:0007005350.041
negative regulation of response to stimulusGO:00485851550.041
negative regulation of gene expressionGO:00106291990.041
negative regulation of macromolecule biosynthetic processGO:00105581480.041
modification dependent macromolecule catabolic processGO:0043632140.040
histone methylationGO:001657130.040
anatomical structure morphogenesisGO:00096532980.040
negative regulation of transcription dna templatedGO:00458921160.040
peptidyl amino acid modificationGO:00181931260.039
centrosome organizationGO:005129710.039
nitrogen compound transportGO:00717052290.038
cellular response to oxygen containing compoundGO:19017013860.038
transmembrane transportGO:00550854120.038
positive regulation of proteasomal protein catabolic processGO:190180030.038
synaptic transmissionGO:00072682350.038
regulation of ion transmembrane transportGO:00347651210.037
cell morphogenesisGO:00009021420.036
single organism catabolic processGO:00447122830.036
Human
dephosphorylationGO:0016311980.036
negative regulation of rna biosynthetic processGO:19026791180.036
regulation of protein modification processGO:00313991940.036
positive regulation of biosynthetic processGO:00098913190.036
neuron projection morphogenesisGO:00488121220.036
regulation of blood circulationGO:19035221100.035
cell projection organizationGO:00300303020.035
circulatory system processGO:00030131830.035
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.034
developmental process involved in reproductionGO:00030061590.034
negative regulation of macromolecule metabolic processGO:00106052600.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
response to oxidative stressGO:00069791860.034
endomembrane system organizationGO:0010256480.033
spermatogenesisGO:0007283990.033
somatic stem cell divisionGO:004810320.033
positive regulation of pseudopodium assemblyGO:003127410.033
calcium ion transmembrane transportGO:0070588700.033
regulation of actin filament based processGO:0032970420.033
small molecule biosynthetic processGO:00442831240.032
multicellular organismal reproductive processGO:00486092330.032
oligopeptide transportGO:000685740.032
calcium ion transportGO:00068161310.032
dendrite developmentGO:0016358720.031
response to ethanolGO:00454711620.031
nucleobase containing small molecule metabolic processGO:00550863160.031
positive regulation of protein metabolic processGO:00512471780.030
protein phosphorylationGO:00064683450.030
carbohydrate derivative metabolic processGO:19011353460.030
Human
growthGO:00400071650.030
response to xenobiotic stimulusGO:0009410230.030
positive regulation of cellular biosynthetic processGO:00313282950.029
cellular amine metabolic processGO:0044106380.029
Human
hair follicle developmentGO:000194220.029
dna metabolic processGO:0006259960.028
ribonucleoside metabolic processGO:00091191740.028
Human
embryonic axis specificationGO:000057810.028
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243630.028
pigment biosynthetic processGO:004614840.028
Human
neuron differentiationGO:00301823680.028
protein oligomerizationGO:00512591910.028
Human
regulation of protein transportGO:0051223680.028
embryo developmentGO:0009790490.028
negative regulation of signalingGO:00230571570.028
negative regulation of biosynthetic processGO:00098901680.027
positive regulation of nitrogen compound metabolic processGO:00511733340.027
Human
response to cytokineGO:00340972150.027
synaptic growth at neuromuscular junctionGO:005112410.027
positive regulation of cell projection organizationGO:00313461110.027
neurotransmitter uptakeGO:000150430.027
cytoskeleton organizationGO:00070101110.027
neuron deathGO:00709971270.027
organelle localizationGO:0051640550.026
microtubule organizing center organizationGO:003102310.026
anion transportGO:00068201780.026
protein refoldingGO:004202630.026
cell part morphogenesisGO:00329901230.026
cellular ketone metabolic processGO:0042180510.025
regulation of cellular amine metabolic processGO:003323880.025
Human
divalent inorganic cation transportGO:00725111340.025
nucleosome organizationGO:003472810.025
positive regulation of transportGO:00510502450.025
regulation of molecular functionGO:00650093980.025
regulation of cell morphogenesis involved in differentiationGO:0010769720.025
cellular response to peptide hormone stimulusGO:00713751200.025
glial cell apoptotic processGO:003434980.025
response to metal ionGO:00100382530.025
central nervous system developmentGO:00074173110.025
positive regulation of cell differentiationGO:00455972170.025
catabolic processGO:00090563510.025
Human
positive regulation of cell developmentGO:00107201760.025
positive regulation of response to stimulusGO:00485842850.025
ribonucleotide metabolic processGO:00092592310.024
Human
positive regulation of dna metabolic processGO:0051054390.024
cell morphogenesis involved in differentiationGO:00009041190.024
halogenated hydrocarbon metabolic processGO:004219740.024
gland developmentGO:00487321550.024
negative regulation of cell cycle phase transitionGO:190198840.024
cellular divalent inorganic cation homeostasisGO:00725031620.023
protein homooligomerizationGO:0051260910.023
Human
response to inorganic substanceGO:00100353770.023
positive regulation of developmental processGO:00510942830.023
hair cycle processGO:002240520.023
response to external biotic stimulusGO:00432072210.023
positive regulation of transcription dna templatedGO:00458931970.023
cellular homeostasisGO:00197252520.022
homeostatic processGO:00425923310.022
nucleoside triphosphate metabolic processGO:00091411440.022
gamete generationGO:00072761240.022
positive regulation of cellular amine metabolic processGO:003324030.022
Human
cell fate determinationGO:000170920.022
cell type specific apoptotic processGO:00972851340.022
phospholipid metabolic processGO:0006644610.022
regulation of metalloenzyme activityGO:004855210.022
positive regulation of cellular protein metabolic processGO:00322701670.022
cytosolic calcium ion homeostasisGO:00514801400.022
response to other organismGO:00517072200.022
digestive system developmentGO:0055123410.021
positive regulation of cell proliferationGO:00082842490.021
purine nucleoside catabolic processGO:00061521240.021
Human
pseudopodium organizationGO:003126830.021
regulation of cellular protein metabolic processGO:00322682670.021
male gamete generationGO:0048232990.021
modification dependent protein catabolic processGO:0019941140.021
regulation of proteolysisGO:0030162660.021
multi organism reproductive processGO:00447032620.021
cardiac muscle cell contractionGO:0086003100.020
purine nucleotide metabolic processGO:00061632290.020
Human
regulation of neuron projection developmentGO:00109751610.020
protein modification by small protein conjugation or removalGO:0070647350.020
brain developmentGO:00074202470.020
ribose phosphate metabolic processGO:00196932350.020
Human
regulation of cell growthGO:0001558850.020
positive regulation of cellular component organizationGO:00511302000.020
purine ribonucleotide metabolic processGO:00091502270.020
Human
nucleoside phosphate metabolic processGO:00067532830.020
Human
response to starvationGO:0042594590.020
regulation of neuron apoptotic processGO:0043523830.019
positive regulation of multicellular organismal processGO:00512403870.019
carboxylic acid transportGO:00469421150.019
cellular macromolecule catabolic processGO:0044265290.019
mapk cascadeGO:00001651400.019
cellular response to nitrogen compoundGO:19016992100.019
regulation of heart contractionGO:0008016480.019
cellular macromolecular complex assemblyGO:0034622580.019
chromosome segregationGO:000705920.018
regulation of transporter activityGO:0032409500.018
centrosome cycleGO:000709810.018
protein transportGO:00150311320.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
regulation of striated muscle contractionGO:0006942210.018
regulation of neuron differentiationGO:00456642080.018
negative regulation of transportGO:00510511360.018
cardiac muscle contractionGO:0060048270.018
multi multicellular organism processGO:00447061380.018
locomotionGO:00400112370.018
cellular lipid metabolic processGO:00442552080.018
positive regulation of phosphorylationGO:00423271770.018
regulation of cellular response to stressGO:0080135490.018
cardiovascular system developmentGO:00723581340.018
immune response to tumor cellGO:000241830.017
response to corticosteroidGO:00319602350.017
purine containing compound metabolic processGO:00725212530.017
pigment metabolic processGO:004244070.017
Human
organ regenerationGO:00311001010.017
negative regulation of cellular metabolic processGO:00313242810.017
embryonic pattern specificationGO:000988010.017
cellular response to external stimulusGO:00714961180.017
regulation of intracellular signal transductionGO:19025312180.017
positive regulation of molecular functionGO:00440932300.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
response to woundingGO:00096112540.017
dendrite morphogenesisGO:0048813430.017
regulation of ion transmembrane transporter activityGO:0032412480.017
mitotic spindle organizationGO:000705220.017
response to bacteriumGO:00096172000.017
negative regulation of cell communicationGO:00106481580.017
multicellular organism growthGO:003526410.016
reactive oxygen species biosynthetic processGO:190340980.016
organophosphate metabolic processGO:00196373700.016
Human
cell adhesionGO:00071551100.016
regulation of phosphate metabolic processGO:00192203490.016
autophagic cell deathGO:004810240.016
regulation of protein localizationGO:0032880810.016
gastrulationGO:000736920.016
canonical wnt signaling pathwayGO:006007090.016
glycosyl compound metabolic processGO:19016571820.016
Human
cell growthGO:00160491040.016
protein ubiquitinationGO:0016567280.016
response to lipopolysaccharideGO:00324961910.016
protein localization to membraneGO:0072657360.016
female pregnancyGO:00075651220.016
muscle contractionGO:0006936880.015
posttranscriptional regulation of gene expressionGO:0010608370.015
protein prenylationGO:001834240.015
positive regulation of signalingGO:00230562700.015
cellular response to nutrient levelsGO:0031669600.015
regulation of neurogenesisGO:00507672470.015
nucleotide biosynthetic processGO:0009165980.015
Human
peptide transportGO:0015833970.015
striated muscle contractionGO:0006941440.015
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.015
regulation of cellular component movementGO:00512701500.015
regulation of kinase activityGO:00435491170.015
toxin transportGO:190199830.015
positive regulation of protein kinase activityGO:0045860730.015
negative regulation of cellular component organizationGO:0051129830.015
reproductive structure developmentGO:00486081280.015
intracellular signal transductionGO:00355563140.015
positive regulation of lipid kinase activityGO:009021820.014
tissue developmentGO:00098882520.014
establishment of organelle localizationGO:0051656370.014
cell cell signalingGO:00072673350.014
cellular response to organonitrogen compoundGO:00714171970.014
regulation of peptide transportGO:0090087870.014
asymmetric stem cell divisionGO:009872220.014
chromosome organizationGO:0051276360.014
regulation of nervous system developmentGO:00519602640.014
positive regulation of lamellipodium assemblyGO:001059240.014
circulatory system developmentGO:00723591340.014
regulation of reactive oxygen species biosynthetic processGO:190342650.014
xenobiotic metabolic processGO:0006805190.014
regulation of mapk cascadeGO:00434081160.014
cellular component movementGO:00069282480.014
skin morphogenesisGO:004358920.014
response to alkaloidGO:00432791320.014
positive regulation of transporter activityGO:0032411140.014
positive regulation of calcium ion transmembrane transporter activityGO:190102170.014
inflammatory responseGO:00069541500.014
reactive nitrogen species metabolic processGO:200105710.014
regulation of anatomical structure sizeGO:00900661350.013
response to biotic stimulusGO:00096072260.013
regulation of muscle system processGO:0090257790.013
defense responseGO:00069521940.013
positive regulation of apoptotic processGO:00430651540.013
cellular chemical homeostasisGO:00550822470.013
cellular carbohydrate metabolic processGO:0044262720.013
melanosome localizationGO:003240010.013
regulation of protein kinase activityGO:00458591050.013
molting cycle processGO:002240420.013
positive regulation of ion transportGO:0043270940.013
organic acid biosynthetic processGO:0016053830.013
purine nucleoside metabolic processGO:00422781690.013
Human
histone h3 acetylationGO:004396620.013
positive regulation of transmembrane transportGO:0034764250.013
carboxylic acid biosynthetic processGO:0046394830.013
anterior posterior pattern specificationGO:000995210.013
molting cycleGO:004230330.013
cellular calcium ion homeostasisGO:00068741600.013
organ morphogenesisGO:0009887750.013
organelle assemblyGO:0070925220.013
chromatin organizationGO:0006325340.013
chromatin remodelingGO:000633830.013
negative regulation of cellular protein metabolic processGO:00322691060.013
cellular protein complex assemblyGO:0043623440.012
regulation of system processGO:00440572080.012
positive regulation of phosphorus metabolic processGO:00105622620.012
positive regulation of rna metabolic processGO:00512542030.012
lipid metabolic processGO:00066292830.012
regulation of protein heterodimerization activityGO:004349710.012
regulation of inflammatory responseGO:0050727480.012
response to growth factorGO:00708481890.012
regulation of dna metabolic processGO:0051052600.012
wnt signaling pathwayGO:0016055170.012
chromatin assembly or disassemblyGO:000633310.012
single organism membrane organizationGO:0044802740.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
negative regulation of hydrogen peroxide biosynthetic processGO:001073020.012
regulation of cell projection organizationGO:00313441750.012
cellular response to growth factor stimulusGO:00713631620.012
heart developmentGO:0007507720.012
cellular response to starvationGO:0009267270.012
actin filament organizationGO:0007015420.012
response to nutrientGO:00075842480.012
positive regulation of neuron differentiationGO:00456661260.012
regulation of embryonic developmentGO:004599520.012
agingGO:00075682410.012
positive regulation of calcium transporting atpase activityGO:190189610.011
regulation of protein serine threonine kinase activityGO:0071900640.011
mast cell migrationGO:009753140.011
pseudopodium assemblyGO:003126930.011
palate developmentGO:006002120.011
vesicle localizationGO:0051648330.011
cell cycle checkpointGO:000007520.011
positive regulation of smoothened signaling pathwayGO:004588010.011
negative regulation of reactive oxygen species metabolic processGO:200037870.011
negative regulation of signal transductionGO:0009968830.011
single organism cellular localizationGO:19025801020.011
covalent chromatin modificationGO:0016569300.011
chlorinated hydrocarbon metabolic processGO:004219640.010
regulation of synaptic transmissionGO:00508041410.010
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278730.010
mitotic cell cycle processGO:1903047350.010
purine ribonucleoside metabolic processGO:00461281680.010
Human
muscle structure developmentGO:0061061870.010
nucleoside phosphate biosynthetic processGO:19012931020.010
Human
response to activityGO:0014823730.010
chromatin modificationGO:0016568330.010
head developmentGO:00603222470.010
cellular macromolecule localizationGO:00707271220.010
histone modificationGO:0016570300.010
negative regulation of ion transportGO:0043271510.010
cellular nitrogen compound catabolic processGO:00442701630.010
Human
metal ion homeostasisGO:00550651860.010
positive regulation of protein modification processGO:00314011420.010

Hprt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.071
disease of anatomical entityDOID:700.071
myopathyDOID:42300.030
muscular diseaseDOID:008000000.030
musculoskeletal system diseaseDOID:1700.030
muscular dystrophyDOID:988400.030
muscle tissue diseaseDOID:6600.030
sensory system diseaseDOID:005015500.022
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.015