Rattus norvegicus

85 known processes

Pink1

PTEN induced putative kinase 1

(Aliases: MGC189438)

Pink1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.250
carboxylic acid metabolic processGO:00197522890.227
organic acid metabolic processGO:00060822920.217
cellular lipid catabolic processGO:0044242370.169
catabolic processGO:00090563510.138
organic substance catabolic processGO:19015753160.137
negative regulation of cellular metabolic processGO:00313242810.120
lipid metabolic processGO:00066292830.119
acetyl coa biosynthetic processGO:000608560.118
cofactor metabolic processGO:0051186950.105
cellular ketone metabolic processGO:0042180510.098
regulation of cellular ketone metabolic processGO:0010565270.095
regulation of protein metabolic processGO:00512462890.091
response to nutrient levelsGO:00316673700.091
intracellular signal transductionGO:00355563140.088
negative regulation of macromolecule metabolic processGO:00106052600.085
cellular response to endogenous stimulusGO:00714953770.081
cellular catabolic processGO:00442482950.079
regulation of coenzyme metabolic processGO:005119610.079
coenzyme biosynthetic processGO:0009108220.075
regulation of phosphorylationGO:00423252480.075
protein complex subunit organizationGO:00718223020.074
positive regulation of multicellular organismal processGO:00512403870.074
coenzyme metabolic processGO:0006732860.070
apoptotic processGO:00069153810.068
single organism catabolic processGO:00447122830.068
negative regulation of nitrogen compound metabolic processGO:00511721610.067
transcription dna templatedGO:00063513770.067
response to oxidative stressGO:00069791860.064
cellular amino acid metabolic processGO:00065201070.063
negative regulation of phosphorus metabolic processGO:0010563800.061
cellular response to organonitrogen compoundGO:00714171970.060
negative regulation of gene expressionGO:00106291990.060
protein complex biogenesisGO:00702712630.057
protein homooligomerizationGO:0051260910.055
negative regulation of biosynthetic processGO:00098901680.054
regulation of protein modification processGO:00313991940.054
regulation of rna metabolic processGO:00512523910.053
regulation of rna biosynthetic processGO:20011413810.053
negative regulation of cellular biosynthetic processGO:00313271610.052
regulation of proteasomal protein catabolic processGO:006113640.052
neuron differentiationGO:00301823680.052
negative regulation of multicellular organismal processGO:00512412030.052
cellular carbohydrate metabolic processGO:0044262720.051
rna metabolic processGO:00160704060.050
positive regulation of neurogenesisGO:00507691650.049
neurological system processGO:00508772190.048
macromolecular complex assemblyGO:00650032730.048
protein phosphorylationGO:00064683450.047
macromolecular complex subunit organizationGO:00439333390.047
cellular component assemblyGO:00226073600.047
carbohydrate metabolic processGO:00059751300.046
regulation of cell proliferationGO:00421273590.046
regulation of lipid metabolic processGO:0019216680.044
protein complex assemblyGO:00064612630.044
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.043
cellular lipid metabolic processGO:00442552080.043
positive regulation of nucleic acid templated transcriptionGO:19035081970.042
positive regulation of rna metabolic processGO:00512542030.042
response to extracellular stimulusGO:00099913800.041
regulation of cell differentiationGO:00455953200.041
regulation of nucleic acid templated transcriptionGO:19035063800.041
cellular component biogenesisGO:00440853680.040
cellular response to extracellular stimulusGO:0031668730.040
chromosome segregationGO:000705920.040
thioester biosynthetic processGO:003538470.039
amine metabolic processGO:0009308380.039
cellular amine metabolic processGO:0044106380.039
anatomical structure morphogenesisGO:00096532980.038
negative regulation of phosphate metabolic processGO:0045936800.038
positive regulation of signalingGO:00230562700.038
transcription from rna polymerase ii promoterGO:00063662520.038
central nervous system developmentGO:00074173110.038
regulation of multicellular organismal developmentGO:20000263760.037
regulation of cellular amine metabolic processGO:003323880.037
regulation of apoptotic processGO:00429813350.037
small molecule catabolic processGO:0044282590.036
cellular response to stressGO:00335542690.036
negative regulation of signalingGO:00230571570.035
negative regulation of metabolic processGO:00098923310.035
single organism biosynthetic processGO:00447113420.034
multicellular organism reproductionGO:00325042330.034
regulation of signal transductionGO:00099663180.034
positive regulation of cell communicationGO:00106472710.034
regulation of transcription dna templatedGO:00063553740.034
positive regulation of signal transductionGO:00099671750.034
negative regulation of cell proliferationGO:00082851190.034
acetyl coa biosynthetic process from pyruvateGO:000608650.034
single organism carbohydrate metabolic processGO:00447231180.033
cellular response to oxygen containing compoundGO:19017013860.032
rna biosynthetic processGO:00327743800.031
transmission of nerve impulseGO:0019226420.031
regulation of catabolic processGO:00098941130.031
negative regulation of cellular protein metabolic processGO:00322691060.031
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
behaviorGO:00076102050.030
neuron developmentGO:00486662860.029
cation homeostasisGO:00550801950.029
positive regulation of cell developmentGO:00107201760.029
ion homeostasisGO:00508012120.029
negative regulation of rna biosynthetic processGO:19026791180.029
multi organism reproductive processGO:00447032620.029
carboxylic acid biosynthetic processGO:0046394830.028
acetyl coa metabolic processGO:0006084170.028
positive regulation of developmental processGO:00510942830.028
positive regulation of gene expressionGO:00106282440.028
cellular response to acid chemicalGO:0071229750.028
negative regulation of rna metabolic processGO:00512531230.028
regulation of phosphate metabolic processGO:00192203490.028
reproductionGO:00000032450.028
negative regulation of erk1 and erk2 cascadeGO:007037390.028
programmed cell deathGO:00125013920.027
oxidation reduction processGO:00551143040.027
nucleic acid templated transcriptionGO:00976593790.027
reproductive processGO:00224143720.027
regulation of intracellular signal transductionGO:19025312180.027
positive regulation of nervous system developmentGO:00519621780.027
brain developmentGO:00074202470.027
cellular response to lipidGO:00713962010.026
signal transduction by phosphorylationGO:00230141440.026
positive regulation of cellular protein metabolic processGO:00322701670.026
positive regulation of protein modification processGO:00314011420.026
positive regulation of molecular functionGO:00440932300.026
positive regulation of neuron differentiationGO:00456661260.026
sulfur compound metabolic processGO:0006790700.026
response to other organismGO:00517072200.026
positive regulation of biosynthetic processGO:00098913190.025
regulation of nervous system developmentGO:00519602640.025
negative regulation of transcription dna templatedGO:00458921160.025
regulation of cellular catabolic processGO:00313291010.025
regulation of cellular amino acid metabolic processGO:000652120.025
positive regulation of protein metabolic processGO:00512471780.025
fatty acid oxidationGO:0019395290.025
cofactor biosynthetic processGO:0051188280.025
acyl coa metabolic processGO:0006637280.024
cation transportGO:00068123820.024
negative regulation of mapk cascadeGO:0043409200.023
regulation of gluconeogenesisGO:000611140.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
negative regulation of programmed cell deathGO:00430691830.022
organonitrogen compound biosynthetic processGO:19015661670.022
signal releaseGO:00230611450.022
multicellular organismal reproductive processGO:00486092330.022
nucleobase containing small molecule metabolic processGO:00550863160.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
organelle organizationGO:00069962660.022
negative regulation of response to stimulusGO:00485851550.022
hexose metabolic processGO:0019318580.022
carbohydrate derivative metabolic processGO:19011353460.022
positive regulation of cellular component organizationGO:00511302000.022
response to peptideGO:19016522920.022
tissue developmentGO:00098882520.021
organic acid biosynthetic processGO:0016053830.021
nitrogen compound transportGO:00717052290.021
neuron projection developmentGO:00311752730.021
response to inorganic substanceGO:00100353770.021
regulation of neuron differentiationGO:00456642080.021
lipid modificationGO:0030258520.021
regulation of protein kinase activityGO:00458591050.021
developmental process involved in reproductionGO:00030061590.021
regulation of mapk cascadeGO:00434081160.021
inorganic cation transmembrane transportGO:00986622020.020
antral ovarian follicle growthGO:000154730.020
muscle contractionGO:0006936880.020
positive regulation of cellular biosynthetic processGO:00313282950.020
organic hydroxy compound metabolic processGO:19016151150.020
positive regulation of rna biosynthetic processGO:19026801970.020
response to peptide hormoneGO:00434342780.020
cellular response to hormone stimulusGO:00328702470.020
alcohol metabolic processGO:0006066770.020
positive regulation of apoptotic processGO:00430651540.020
protein tetramerizationGO:0051262380.020
regulation of ion transportGO:00432692450.019
negative regulation of innate immune responseGO:004582440.019
chemical homeostasisGO:00488782920.019
positive regulation of proteasomal protein catabolic processGO:190180030.019
ion transmembrane transportGO:00342203650.019
protein catabolic processGO:0030163300.019
cellular homeostasisGO:00197252520.019
positive regulation of programmed cell deathGO:00430681570.019
hormone transportGO:00099141210.019
regulation of response to stressGO:00801341260.019
regulation of neuron deathGO:19012141150.019
mitotic spindle organizationGO:000705220.019
purine containing compound metabolic processGO:00725212530.018
sulfur compound biosynthetic processGO:0044272190.018
cellular calcium ion homeostasisGO:00068741600.018
hormone secretionGO:00468791150.018
single organism reproductive processGO:00447022970.018
regulation of transferase activityGO:00513381230.018
response to ketoneGO:19016541820.018
monocarboxylic acid metabolic processGO:00327871520.018
cellular response to nutrient levelsGO:0031669600.018
glycosyl compound metabolic processGO:19016571820.018
organophosphate metabolic processGO:00196373700.018
regulation of kinase activityGO:00435491170.018
regulation of molecular functionGO:00650093980.018
response to oxygen levelsGO:00704822650.018
forebrain developmentGO:0030900980.017
head developmentGO:00603222470.017
acyl coa biosynthetic processGO:007161670.017
negative regulation of signal transductionGO:0009968830.017
monosaccharide metabolic processGO:0005996610.017
positive regulation of transcription dna templatedGO:00458931970.017
regulation of neurogenesisGO:00507672470.017
calcium ion homeostasisGO:00550741620.017
cell projection organizationGO:00300303020.017
cytoskeleton organizationGO:00070101110.017
organic acid catabolic processGO:0016054490.017
spindle organizationGO:000705120.017
maintenance of locationGO:0051235170.017
homeostatic processGO:00425923310.017
smooth muscle cell proliferationGO:0048659770.016
response to nutrientGO:00075842480.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
fatty acid beta oxidationGO:0006635220.016
action potentialGO:0001508540.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
regulation of system processGO:00440572080.016
blood circulationGO:00080151830.016
response to ethanolGO:00454711620.016
response to organophosphorusGO:00466831020.016
positive regulation of phosphorylationGO:00423271770.016
regulation of cellular protein metabolic processGO:00322682670.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
gamete generationGO:00072761240.016
cellular response to growth factor stimulusGO:00713631620.015
intracellular transportGO:00469071850.015
cellular response to external stimulusGO:00714961180.015
cellular response to nutrientGO:0031670300.015
positive regulation of protein phosphorylationGO:00019341350.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
cytokine productionGO:0001816610.015
positive regulation of response to stimulusGO:00485842850.015
regulation of protein catabolic processGO:0042176160.015
positive regulation of cell differentiationGO:00455972170.015
regulation of phosphorus metabolic processGO:00511743490.015
regulation of neuron projection developmentGO:00109751610.014
macromolecule localizationGO:00330362520.014
learning or memoryGO:0007611900.014
regulation of cell maturationGO:190342930.014
positive regulation of lipid catabolic processGO:005099640.014
regulation of cellular component biogenesisGO:0044087860.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
calcium ion transportGO:00068161310.014
muscle structure developmentGO:0061061870.014
cognitionGO:0050890920.014
cytosolic calcium ion homeostasisGO:00514801400.014
insulin secretionGO:0030073690.014
positive regulation of hormone secretionGO:0046887650.014
fatty acid metabolic processGO:0006631990.014
response to metal ionGO:00100382530.014
positive regulation of neuron projection developmentGO:0010976990.014
nucleoside phosphate biosynthetic processGO:19012931020.014
cellular response to nitrogen compoundGO:19016992100.014
cellular amino acid catabolic processGO:0009063210.014
response to temperature stimulusGO:0009266940.014
triglyceride metabolic processGO:0006641210.014
negative regulation of apoptotic processGO:00430661810.014
divalent inorganic cation homeostasisGO:00725071650.014
cellular component morphogenesisGO:00329891550.014
glycerolipid metabolic processGO:0046486670.014
cellular response to peptide hormone stimulusGO:00713751200.013
regulation of cytokine productionGO:0001817560.013
kidney developmentGO:0001822670.013
regulation of protein phosphorylationGO:00019321830.013
cell cell signalingGO:00072673350.013
sexual reproductionGO:00199531480.013
muscle system processGO:00030121150.013
regulation of erk1 and erk2 cascadeGO:0070372410.013
positive regulation of cell projection organizationGO:00313461110.013
regulation of cell developmentGO:00602842630.013
positive regulation of intracellular signal transductionGO:19025331380.013
proteolysisGO:00065081750.013
glucose metabolic processGO:0006006520.013
negative regulation of protein phosphorylationGO:0001933440.013
regulation of protein serine threonine kinase activityGO:0071900640.013
metal ion transportGO:00300012890.013
regulation of programmed cell deathGO:00430673410.013
microtubule based processGO:0007017360.013
positive regulation of cellular catabolic processGO:0031331710.013
protein oligomerizationGO:00512591910.013
positive regulation of cellular amine metabolic processGO:003324030.013
carbohydrate derivative biosynthetic processGO:19011371240.012
amide transportGO:00428861050.012
reproductive system developmentGO:00614581280.012
cell morphogenesis involved in differentiationGO:00009041190.012
regulation of metal ion transportGO:00109591180.012
negative regulation of intracellular signal transductionGO:1902532380.012
negative regulation of response to biotic stimulusGO:000283240.012
acetate ester biosynthetic processGO:190062020.012
response to estradiolGO:00323551640.012
regulation of transmembrane transportGO:00347621220.012
secretionGO:00469033070.012
positive regulation of catabolic processGO:0009896780.012
cellular macromolecule localizationGO:00707271220.012
cellular response to insulin stimulusGO:0032869810.012
defense responseGO:00069521940.012
peptide transportGO:0015833970.012
purine nucleoside metabolic processGO:00422781690.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
regulation of cellular component organizationGO:00511283680.012
dendrite morphogenesisGO:0048813430.012
regulation of smooth muscle cell proliferationGO:0048660750.012
negative regulation of molecular functionGO:00440921330.012
gastrulationGO:000736920.012
regulation of peptide hormone secretionGO:0090276800.012
negative regulation of cellular amine metabolic processGO:003323930.012
inorganic ion transmembrane transportGO:00986602290.012
erk1 and erk2 cascadeGO:0070371480.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
metal ion homeostasisGO:00550651860.011
peptidyl amino acid modificationGO:00181931260.011
response to alkaloidGO:00432791320.011
monocarboxylic acid biosynthetic processGO:0072330480.011
response to toxic substanceGO:00096361330.011
reproductive structure developmentGO:00486081280.011
monocarboxylic acid transportGO:0015718520.011
cell morphogenesisGO:00009021420.011
neuron deathGO:00709971270.011
regulation of anatomical structure sizeGO:00900661350.011
small gtpase mediated signal transductionGO:0007264360.011
cellular response to organic cyclic compoundGO:00714072020.011
secretion by cellGO:00329402480.011
eye morphogenesisGO:004859240.011
positive regulation of phosphorus metabolic processGO:00105622620.011
negative regulation of protein metabolic processGO:00512481140.011
cellular chemical homeostasisGO:00550822470.011
regulation of calcium ion transmembrane transportGO:1903169180.011
reactive oxygen species metabolic processGO:0072593370.011
cellular metal ion homeostasisGO:00068751720.011
meiotic cell cycle processGO:190304630.011
regulation of homeostatic processGO:00328441010.011
axis specificationGO:000979840.011
single organism behaviorGO:00447081300.011
cytoplasmic transportGO:00164821150.011
response to antibioticGO:0046677390.010
dendrite developmentGO:0016358720.010
regulation of hormone levelsGO:00108171870.010
rna localizationGO:000640340.010
positive regulation of cell deathGO:00109421840.010
regulation of map kinase activityGO:0043405530.010
regulation of cell projection organizationGO:00313441750.010
circulatory system processGO:00030131830.010
gland developmentGO:00487321550.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
cell projection morphogenesisGO:00488581230.010
mapk cascadeGO:00001651400.010
peptide secretionGO:0002790860.010
negative regulation of catalytic activityGO:00430861030.010

Pink1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.083
disease of metabolismDOID:001466700.083
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
central nervous system diseaseDOID:33100.015
carbohydrate metabolic disorderDOID:297800.014