Rattus norvegicus

99 known processes

Nfkbia

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

(Aliases: RL/IF-1)

Nfkbia biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to stressGO:00335542690.627
Fly
rna biosynthetic processGO:00327743800.550
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511721610.546
regulation of nucleic acid templated transcriptionGO:19035063800.486
Human Mouse
rna metabolic processGO:00160704060.448
Human Mouse
regulation of rna metabolic processGO:00512523910.446
Human Mouse
regulation of rna biosynthetic processGO:20011413810.433
Human Mouse
transcription from rna polymerase ii promoterGO:00063662520.426
Human
regulation of cell proliferationGO:00421273590.417
Mouse
negative regulation of cellular metabolic processGO:00313242810.375
oxoacid metabolic processGO:00434362900.324
transcription dna templatedGO:00063513770.315
Human Mouse
negative regulation of metabolic processGO:00098923310.310
negative regulation of biosynthetic processGO:00098901680.306
regulation of transcription dna templatedGO:00063553740.300
Human Mouse
negative regulation of macromolecule metabolic processGO:00106052600.277
negative regulation of signalingGO:00230571570.276
organic acid metabolic processGO:00060822920.245
positive regulation of nucleobase containing compound metabolic processGO:00459353190.225
Human Mouse
cellular amino acid metabolic processGO:00065201070.222
apoptotic processGO:00069153810.218
neuron deathGO:00709971270.212
regulation of apoptotic processGO:00429813350.211
cellular ketone metabolic processGO:0042180510.211
positive regulation of rna metabolic processGO:00512542030.207
Human Mouse
programmed cell deathGO:00125013920.207
cellular response to hormone stimulusGO:00328702470.205
positive regulation of nitrogen compound metabolic processGO:00511733340.199
Human Mouse Fly
regulation of interleukin 6 productionGO:0032675120.183
amine metabolic processGO:0009308380.181
regulation of transcription from rna polymerase ii promoterGO:00063572340.176
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.167
organic substance catabolic processGO:19015753160.160
peptidyl amino acid modificationGO:00181931260.155
positive regulation of multicellular organismal processGO:00512403870.148
carboxylic acid metabolic processGO:00197522890.145
cellular response to oxygen containing compoundGO:19017013860.145
Mouse
response to nutrient levelsGO:00316673700.145
nucleic acid templated transcriptionGO:00976593790.144
Human Mouse
response to external biotic stimulusGO:00432072210.141
Mouse Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.139
Human
regulation of cellular protein metabolic processGO:00322682670.138
Human
cellular catabolic processGO:00442482950.138
regulation of gene expression epigeneticGO:0040029100.137
negative regulation of response to stimulusGO:00485851550.134
reproductive processGO:00224143720.133
Fly
negative regulation of molecular functionGO:00440921330.131
Human
positive regulation of gene expressionGO:00106282440.127
Human Mouse
negative regulation of cell deathGO:00605482290.126
negative regulation of apoptotic processGO:00430661810.126
positive regulation of nucleic acid templated transcriptionGO:19035081970.125
Human Mouse
regulation of signal transductionGO:00099663180.124
negative regulation of phosphorus metabolic processGO:0010563800.121
intracellular signal transductionGO:00355563140.116
catabolic processGO:00090563510.113
response to peptideGO:19016522920.111
Mouse
regulation of cellular amine metabolic processGO:003323880.111
regulation of protein metabolic processGO:00512462890.109
Human
positive regulation of biosynthetic processGO:00098913190.107
Human Mouse Fly
neuron differentiationGO:00301823680.104
peptidyl tyrosine modificationGO:0018212720.103
regulation of cellular ketone metabolic processGO:0010565270.101
cation transportGO:00068123820.101
Rat
regulation of protein modification processGO:00313991940.099
negative regulation of rna biosynthetic processGO:19026791180.098
cellular amine metabolic processGO:0044106380.095
regulation of cellular component organizationGO:00511283680.094
monovalent inorganic cation transportGO:00156721720.094
single organism biosynthetic processGO:00447113420.089
response to bacteriumGO:00096172000.084
Mouse
defense responseGO:00069521940.083
Mouse Fly
regulation of phosphorylationGO:00423252480.083
negative regulation of cellular protein metabolic processGO:00322691060.082
agingGO:00075682410.082
cellular response to organonitrogen compoundGO:00714171970.082
regulation of metal ion transportGO:00109591180.080
negative regulation of nucleic acid templated transcriptionGO:19035071170.080
carbohydrate derivative metabolic processGO:19011353460.079
positive regulation of transcription dna templatedGO:00458931970.077
Human Mouse
response to extracellular stimulusGO:00099913800.075
protein autophosphorylationGO:0046777660.074
cytokine productionGO:0001816610.073
regulation of molecular functionGO:00650093980.071
Human
regulation of catalytic activityGO:00507903040.071
anatomical structure morphogenesisGO:00096532980.071
Fly
response to peptide hormoneGO:00434342780.070
negative regulation of protein metabolic processGO:00512481140.070
regulation of mrna 3 end processingGO:003144010.069
negative regulation of transcription dna templatedGO:00458921160.069
protein phosphorylationGO:00064683450.068
regulation of intracellular signal transductionGO:19025312180.066
cellular response to nitrogen compoundGO:19016992100.066
nucleobase containing compound catabolic processGO:00346551520.066
heterocycle catabolic processGO:00467001670.066
negative regulation of signal transductionGO:0009968830.065
regulation of cellular amino acid metabolic processGO:000652120.065
homeostatic processGO:00425923310.064
multicellular organism reproductionGO:00325042330.064
Fly
osteoblast differentiationGO:0001649260.062
dna metabolic processGO:0006259960.061
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.060
positive regulation of cellular biosynthetic processGO:00313282950.060
Human Mouse Fly
negative regulation of cellular biosynthetic processGO:00313271610.059
negative regulation of protein modification processGO:0031400520.059
response to radiationGO:00093141370.058
chemical homeostasisGO:00488782920.058
regulation of cell differentiationGO:00455953200.058
Human Mouse
ribonucleotide metabolic processGO:00092592310.057
organophosphate metabolic processGO:00196373700.055
cellular nitrogen compound catabolic processGO:00442701630.055
cellular response to molecule of bacterial originGO:0071219560.055
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769720.054
regulation of p38mapk cascadeGO:190074410.054
gland developmentGO:00487321550.053
negative regulation of nucleobase containing compound metabolic processGO:00459341530.053
cellular chemical homeostasisGO:00550822470.053
cellular response to oxidative stressGO:0034599760.051
multi organism reproductive processGO:00447032620.051
Fly
negative regulation of gene expressionGO:00106291990.051
mrna stabilizationGO:004825520.051
metal ion transportGO:00300012890.049
negative regulation of protein phosphorylationGO:0001933440.048
positive regulation of cell developmentGO:00107201760.047
enzyme linked receptor protein signaling pathwayGO:00071671160.046
regulation of neuron deathGO:19012141150.046
macromolecular complex subunit organizationGO:00439333390.045
mrna 3 end processingGO:003112410.045
nucleoside phosphate metabolic processGO:00067532830.045
regulation of cytokine productionGO:0001817560.045
nucleoside metabolic processGO:00091161790.044
cellular response to organic cyclic compoundGO:00714072020.044
regulation of cellular catabolic processGO:00313291010.044
response to oxidative stressGO:00069791860.043
purine nucleoside triphosphate catabolic processGO:00091461220.043
regulation of catabolic processGO:00098941130.043
positive regulation of nervous system developmentGO:00519621780.042
positive regulation of cellular component organizationGO:00511302000.041
cellular response to cytokine stimulusGO:00713451270.041
tumor necrosis factor productionGO:0032640130.040
purine nucleotide catabolic processGO:00061951360.040
neurological system processGO:00508772190.039
cellular homeostasisGO:00197252520.038
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.038
intracellular transportGO:00469071850.037
head developmentGO:00603222470.037
positive regulation of catalytic activityGO:00430851840.037
circulatory system processGO:00030131830.037
purine ribonucleotide metabolic processGO:00091502270.037
positive regulation of neurogenesisGO:00507691650.036
positive regulation of rna biosynthetic processGO:19026801970.036
Human Mouse
positive regulation of developmental processGO:00510942830.036
cation homeostasisGO:00550801950.035
negative regulation of macromolecule biosynthetic processGO:00105581480.035
single organism reproductive processGO:00447022970.035
Fly
organonitrogen compound biosynthetic processGO:19015661670.034
Fly
regulation of protein localizationGO:0032880810.034
negative regulation of developmental processGO:00510931250.034
Human Mouse
negative regulation of cytokine productionGO:0001818160.034
negative regulation of programmed cell deathGO:00430691830.034
regulation of neuron projection developmentGO:00109751610.034
cellular ion homeostasisGO:00068731840.034
ribose phosphate metabolic processGO:00196932350.033
positive regulation of signalingGO:00230562700.033
negative regulation of rna metabolic processGO:00512531230.033
posttranscriptional regulation of gene expressionGO:0010608370.032
inflammatory responseGO:00069541500.032
response to inorganic substanceGO:00100353770.032
central nervous system developmentGO:00074173110.032
regulation of protein kinase activityGO:00458591050.032
negative regulation of multicellular organismal processGO:00512412030.032
Mouse
regulation of ion transportGO:00432692450.031
response to nutrientGO:00075842480.031
cellular response to acid chemicalGO:0071229750.031
regulation of growthGO:00400081050.031
dna methylation or demethylationGO:004472880.031
erythrocyte differentiationGO:003021810.031
nitrogen compound transportGO:00717052290.030
negative regulation of phosphate metabolic processGO:0045936800.030
multicellular organism growthGO:003526410.030
protein complex subunit organizationGO:00718223020.030
regulation of programmed cell deathGO:00430673410.030
negative regulation of protein kinase activityGO:0006469230.030
nucleotide metabolic processGO:00091172790.030
purine nucleoside triphosphate metabolic processGO:00091441410.029
positive regulation of mrna metabolic processGO:190331340.029
organic anion transportGO:00157111320.029
Rat
response to molecule of bacterial originGO:00022371940.029
Mouse
aromatic compound catabolic processGO:00194391680.029
positive regulation of cell projection organizationGO:00313461110.029
negative regulation of neuron deathGO:1901215690.028
cellular macromolecule catabolic processGO:0044265290.028
purine containing compound catabolic processGO:00725231380.028
protein localizationGO:00081041910.028
regulation of multicellular organismal developmentGO:20000263760.028
Mouse
organelle organizationGO:00069962660.027
cellular component biogenesisGO:00440853680.026
amide transportGO:00428861050.026
purine nucleotide metabolic processGO:00061632290.026
response to decreased oxygen levelsGO:00362932370.025
regulation of sodium ion transportGO:0002028210.025
protein complex biogenesisGO:00702712630.025
regulation of hydrolase activityGO:00513361430.025
response to other organismGO:00517072200.025
Mouse Fly
positive regulation of cellular amine metabolic processGO:003324030.025
negative regulation of neuron apoptotic processGO:0043524450.024
sodium ion transportGO:0006814820.024
positive regulation of cell differentiationGO:00455972170.024
nucleobase containing small molecule metabolic processGO:00550863160.024
cytoskeleton organizationGO:00070101110.024
positive regulation of cell proliferationGO:00082842490.024
rna stabilizationGO:004348920.024
regulation of neurogenesisGO:00507672470.024
nucleoside triphosphate catabolic processGO:00091431230.024
macromolecule localizationGO:00330362520.024
negative regulation of cell proliferationGO:00082851190.024
anion transportGO:00068201780.023
Rat
cellular cation homeostasisGO:00300031800.023
regulation of phosphorus metabolic processGO:00511743490.023
inactivation of mapk activityGO:000018820.023
ion homeostasisGO:00508012120.023
macromolecule catabolic processGO:0009057580.023
membrane organizationGO:0061024940.023
positive regulation of neuron projection developmentGO:0010976990.023
response to insulinGO:00328681330.022
single organism intracellular transportGO:19025821660.022
lipid storageGO:001991510.022
Human
negative regulation of collagen biosynthetic processGO:003296640.022
nucleoside catabolic processGO:00091641260.022
nucleoside phosphate catabolic processGO:19012921400.022
positive regulation of ion transportGO:0043270940.022
carbohydrate derivative catabolic processGO:19011361470.022
cellular response to insulin stimulusGO:0032869810.022
single organism catabolic processGO:00447122830.022
maintenance of locationGO:0051235170.022
negative regulation of catalytic activityGO:00430861030.022
brain developmentGO:00074202470.022
cell type specific apoptotic processGO:00972851340.022
regulation of cellular response to stressGO:0080135490.021
neuron projection developmentGO:00311752730.021
organic cyclic compound catabolic processGO:19013611750.021
regulation of osteoblast differentiationGO:0045667140.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
cellular metal ion homeostasisGO:00068751720.021
regulation of phosphate metabolic processGO:00192203490.021
cellular response to endogenous stimulusGO:00714953770.021
behaviorGO:00076102050.020
atp metabolic processGO:0046034720.020
vasculature developmentGO:0001944700.020
rna catabolic processGO:000640130.020
positive regulation of catabolic processGO:0009896780.020
mrna processingGO:0006397140.020
regulation of cell projection organizationGO:00313441750.020
cytokine mediated signaling pathwayGO:0019221430.020
cellular response to peptideGO:19016531330.020
response to cytokineGO:00340972150.020
mammary gland epithelium developmentGO:006118010.020
positive regulation of phosphorus metabolic processGO:00105622620.019
regulation of neuron differentiationGO:00456642080.019
cellular sodium ion homeostasisGO:000688340.019
regulation of cell morphogenesisGO:0022604770.019
cytoplasmic transportGO:00164821150.019
regulation of cell developmentGO:00602842630.019
regulation of dendrite developmentGO:0050773590.019
cellular protein localizationGO:00346131220.019
positive regulation of mrna catabolic processGO:006101420.019
lipid biosynthetic processGO:00086101280.019
cell projection organizationGO:00300303020.019
regulation of mrna stabilityGO:004348830.019
response to ethanolGO:00454711620.019
single organism organelle organizationGO:19025891800.018
epithelium developmentGO:0060429960.018
Fly
positive regulation of cell deathGO:00109421840.018
proteolysisGO:00065081750.018
macromolecular complex assemblyGO:00650032730.018
regulation of organelle organizationGO:0033043800.018
memoryGO:0007613540.018
response to growth factorGO:00708481890.018
negative regulation of cell communicationGO:00106481580.018
epithelial cell differentiationGO:0030855710.018
Fly
regulation of dna metabolic processGO:0051052600.017
negative regulation of cell differentiationGO:0045596990.017
Human Mouse
metal ion homeostasisGO:00550651860.017
cellular response to steroid hormone stimulusGO:0071383930.017
regulation of microtubule polymerization or depolymerizationGO:0031110120.017
biological adhesionGO:00226101100.017
peptidyl tyrosine phosphorylationGO:0018108720.017
negative regulation of immune system processGO:0002683390.017
Mouse
regulation of fat cell differentiationGO:004559830.017
neuron developmentGO:00486662860.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
negative regulation of innate immune responseGO:004582440.016
regulation of protein phosphorylationGO:00019321830.016
negative regulation of transportGO:00510511360.016
regulation of tumor necrosis factor productionGO:0032680130.016
negative regulation of cellular amine metabolic processGO:003323930.016
tumor necrosis factor superfamily cytokine productionGO:0071706130.016
ras protein signal transductionGO:0007265290.016
cellular response to follicle stimulating hormone stimulusGO:0071372130.016
regulation of lipid biosynthetic processGO:0046890380.016
response to reactive oxygen speciesGO:00003021200.016
positive regulation of cellular catabolic processGO:0031331710.016
transmembrane transportGO:00550854120.016
purine ribonucleoside metabolic processGO:00461281680.016
regulation of cell growthGO:0001558850.016
purine containing compound biosynthetic processGO:0072522850.016
cellular response to tumor necrosis factorGO:0071356460.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
reproductionGO:00000032450.016
Fly
response to metal ionGO:00100382530.015
negative regulation of ion transportGO:0043271510.015
regulation of microtubule cytoskeleton organizationGO:0070507140.015
regulation of nervous system developmentGO:00519602640.015
response to biotic stimulusGO:00096072260.015
Mouse Fly
tube developmentGO:0035295890.015
positive regulation of neuron differentiationGO:00456661260.015
response to amineGO:0014075460.015
nucleoside monophosphate metabolic processGO:0009123930.015
organophosphate biosynthetic processGO:00904071430.015
response to tumor necrosis factorGO:0034612560.015
cellular response to lipidGO:00713962010.015
Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555130.015
multicellular organismal reproductive processGO:00486092330.015
Fly
calcium ion transportGO:00068161310.015
cellular macromolecule localizationGO:00707271220.015
regulation of rna stabilityGO:004348730.015
nucleotide catabolic processGO:00091661390.014
reactive oxygen species metabolic processGO:0072593370.014
glycosyl compound metabolic processGO:19016571820.014
sexual reproductionGO:00199531480.014
Fly
response to oxygen levelsGO:00704822650.014
growthGO:00400071650.014
small molecule biosynthetic processGO:00442831240.014
peptidyl serine phosphorylationGO:0018105330.014
nucleoside triphosphate metabolic processGO:00091411440.014
divalent metal ion transportGO:00708381320.014
negative regulation of tor signalingGO:003200720.014
heart processGO:0003015570.014
positive regulation of hydrolase activityGO:0051345860.014
cellular response to dna damage stimulusGO:0006974190.014
Fly
cellular response to hydrogen peroxideGO:0070301420.014
cellular component movementGO:00069282480.014
response to carbohydrateGO:00097431830.014
negative regulation of cellular component organizationGO:0051129830.014
regulation of peptidase activityGO:0052547550.013
gtp catabolic processGO:0006184710.013
positive regulation of phosphate metabolic processGO:00459372620.013
single organism membrane organizationGO:0044802740.013
cell adhesionGO:00071551100.013
regulation of protein complex assemblyGO:0043254330.013
regulation of stress activated mapk cascadeGO:0032872230.013
reactive oxygen species biosynthetic processGO:190340980.013
cellular response to peptide hormone stimulusGO:00713751200.013
hormone mediated signaling pathwayGO:0009755230.013
small gtpase mediated signal transductionGO:0007264360.013
response to light stimulusGO:0009416520.013
regulation of protein transportGO:0051223680.013
sphingolipid biosynthetic processGO:003014840.013
response to axon injuryGO:0048678590.013
developmental process involved in reproductionGO:00030061590.013
Fly
positive regulation of molecular functionGO:00440932300.013
cellular component assemblyGO:00226073600.013
regulation of nucleotide metabolic processGO:00061401170.013
hepaticobiliary system developmentGO:0061008900.013
dna modificationGO:0006304120.013
guanosine containing compound catabolic processGO:1901069710.013
interleukin 6 productionGO:0032635120.013
cellular response to glucocorticoid stimulusGO:0071385680.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of transferase activityGO:00513381230.013
negative regulation of transferase activityGO:0051348290.013
p38mapk cascadeGO:003806610.012
ribose phosphate biosynthetic processGO:0046390870.012
steroid metabolic processGO:0008202730.012
protein import into nucleusGO:0006606350.012
regulation of cellular localizationGO:00603412630.012
carboxylic acid transportGO:00469421150.012
Rat
positive regulation of neuron apoptotic processGO:0043525330.012
spermatogenesisGO:0007283990.012
organonitrogen compound catabolic processGO:19015651790.012
regulation of secretionGO:00510462240.012
response to estradiolGO:00323551640.012
nucleocytoplasmic transportGO:0006913480.012
response to mineralocorticoidGO:0051385490.012
embryo developmentGO:0009790490.012
regulation of neuron apoptotic processGO:0043523830.012
purine ribonucleoside monophosphate metabolic processGO:0009167840.012
response to dexamethasoneGO:0071548490.012
positive regulation of mesenchymal cell proliferationGO:000205340.012
neuron apoptotic processGO:0051402880.012
embryonic pattern specificationGO:000988010.012
response to transition metal nanoparticleGO:19902671220.012
purine ribonucleotide catabolic processGO:00091541360.012
regulation of microtubule based processGO:0032886140.012
positive regulation of g0 to g1 transitionGO:007031820.012
purine containing compound metabolic processGO:00725212530.012
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.012
activation of cysteine type endopeptidase activityGO:009720240.012
divalent inorganic cation transportGO:00725111340.011
regulation of peptidyl tyrosine phosphorylationGO:0050730320.011
response to acid chemicalGO:00011012220.011
potassium ion transportGO:0006813970.011
ribonucleoside metabolic processGO:00091191740.011
protein transportGO:00150311320.011
divalent inorganic cation homeostasisGO:00725071650.011
negative regulation of epidermal growth factor receptor signaling pathwayGO:004205930.011
cell growthGO:00160491040.011
glucose metabolic processGO:0006006520.011
positive regulation of nucleoside metabolic processGO:0045979550.011
g protein coupled receptor signaling pathwayGO:00071862420.011
positive regulation of intracellular signal transductionGO:19025331380.011
regulation of defense responseGO:0031347680.011
Mouse Fly
wound healingGO:00420601220.011
cytokine biosynthetic processGO:004208930.011
positive regulation of phosphorylationGO:00423271770.011
response to lipopolysaccharideGO:00324961910.011
Mouse
positive regulation of cellular protein metabolic processGO:00322701670.011
Human
ion transmembrane transportGO:00342203650.011
nucleoside phosphate biosynthetic processGO:19012931020.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
reproductive structure developmentGO:00486081280.011
regulation of anatomical structure sizeGO:00900661350.010
mammary gland developmentGO:0030879380.010
organophosphate catabolic processGO:00464341480.010
photoperiodismGO:000964840.010
cellular response to carbohydrate stimulusGO:0071322720.010
regulation of purine nucleotide metabolic processGO:19005421150.010
response to vitaminGO:00332731310.010
secretionGO:00469033070.010
reactive nitrogen species metabolic processGO:200105710.010
regulation of dna methylationGO:004403060.010
positive regulation of cell growthGO:0030307440.010
response to amino acidGO:0043200750.010
cytosolic calcium ion homeostasisGO:00514801400.010
multicellular organismal signalingGO:0035637440.010

Nfkbia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.027
cancerDOID:16200.021
organ system cancerDOID:005068600.014
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
disease of metabolismDOID:001466700.012