IMP: Integrative Multi-species Prediction

Rattus norvegicus

99 known processes

Nfkbia

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

(Aliases: RL/IF-1)

Entrez: 25493
Ensembl: ENSRNOG00000007390
RGD: 3171
UniProtKB: Q63746

Process Predictions
Disease Predictions

Nfkbia biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular response to stress	GO:0033554	269	0.627	Fly
rna biosynthetic process	GO:0032774	380	0.550	Human Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.546
regulation of nucleic acid templated transcription	GO:1903506	380	0.486	Human Mouse
rna metabolic process	GO:0016070	406	0.448	Human Mouse
regulation of rna metabolic process	GO:0051252	391	0.446	Human Mouse
regulation of rna biosynthetic process	GO:2001141	381	0.433	Human Mouse
transcription from rna polymerase ii promoter	GO:0006366	252	0.426	Human
regulation of cell proliferation	GO:0042127	359	0.417	Mouse
negative regulation of cellular metabolic process	GO:0031324	281	0.375
oxoacid metabolic process	GO:0043436	290	0.324
transcription dna templated	GO:0006351	377	0.315	Human Mouse
negative regulation of metabolic process	GO:0009892	331	0.310
negative regulation of biosynthetic process	GO:0009890	168	0.306
regulation of transcription dna templated	GO:0006355	374	0.300	Human Mouse
negative regulation of macromolecule metabolic process	GO:0010605	260	0.277
negative regulation of signaling	GO:0023057	157	0.276
organic acid metabolic process	GO:0006082	292	0.245
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.225	Human Mouse
cellular amino acid metabolic process	GO:0006520	107	0.222
apoptotic process	GO:0006915	381	0.218
neuron death	GO:0070997	127	0.212
regulation of apoptotic process	GO:0042981	335	0.211
cellular ketone metabolic process	GO:0042180	51	0.211
positive regulation of rna metabolic process	GO:0051254	203	0.207	Human Mouse
programmed cell death	GO:0012501	392	0.207
cellular response to hormone stimulus	GO:0032870	247	0.205
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.199	Human Mouse Fly
regulation of interleukin 6 production	GO:0032675	12	0.183
amine metabolic process	GO:0009308	38	0.181
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.176	Human
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.167
organic substance catabolic process	GO:1901575	316	0.160
peptidyl amino acid modification	GO:0018193	126	0.155
positive regulation of multicellular organismal process	GO:0051240	387	0.148
carboxylic acid metabolic process	GO:0019752	289	0.145
cellular response to oxygen containing compound	GO:1901701	386	0.145	Mouse
response to nutrient levels	GO:0031667	370	0.145
nucleic acid templated transcription	GO:0097659	379	0.144	Human Mouse
response to external biotic stimulus	GO:0043207	221	0.141	Mouse Fly
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.139	Human
regulation of cellular protein metabolic process	GO:0032268	267	0.138	Human
cellular catabolic process	GO:0044248	295	0.138
regulation of gene expression epigenetic	GO:0040029	10	0.137
negative regulation of response to stimulus	GO:0048585	155	0.134
reproductive process	GO:0022414	372	0.133	Fly
negative regulation of molecular function	GO:0044092	133	0.131	Human
positive regulation of gene expression	GO:0010628	244	0.127	Human Mouse
negative regulation of cell death	GO:0060548	229	0.126
negative regulation of apoptotic process	GO:0043066	181	0.126
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.125	Human Mouse
regulation of signal transduction	GO:0009966	318	0.124
negative regulation of phosphorus metabolic process	GO:0010563	80	0.121
intracellular signal transduction	GO:0035556	314	0.116
catabolic process	GO:0009056	351	0.113
response to peptide	GO:1901652	292	0.111	Mouse
regulation of cellular amine metabolic process	GO:0033238	8	0.111
regulation of protein metabolic process	GO:0051246	289	0.109	Human
positive regulation of biosynthetic process	GO:0009891	319	0.107	Human Mouse Fly
neuron differentiation	GO:0030182	368	0.104
peptidyl tyrosine modification	GO:0018212	72	0.103
regulation of cellular ketone metabolic process	GO:0010565	27	0.101
cation transport	GO:0006812	382	0.101	Rat
regulation of protein modification process	GO:0031399	194	0.099
negative regulation of rna biosynthetic process	GO:1902679	118	0.098
cellular amine metabolic process	GO:0044106	38	0.095
regulation of cellular component organization	GO:0051128	368	0.094
monovalent inorganic cation transport	GO:0015672	172	0.094
single organism biosynthetic process	GO:0044711	342	0.089
response to bacterium	GO:0009617	200	0.084	Mouse
defense response	GO:0006952	194	0.083	Mouse Fly
regulation of phosphorylation	GO:0042325	248	0.083
negative regulation of cellular protein metabolic process	GO:0032269	106	0.082
aging	GO:0007568	241	0.082
cellular response to organonitrogen compound	GO:0071417	197	0.082
regulation of metal ion transport	GO:0010959	118	0.080
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.080
carbohydrate derivative metabolic process	GO:1901135	346	0.079
positive regulation of transcription dna templated	GO:0045893	197	0.077	Human Mouse
response to extracellular stimulus	GO:0009991	380	0.075
protein autophosphorylation	GO:0046777	66	0.074
cytokine production	GO:0001816	61	0.073
regulation of molecular function	GO:0065009	398	0.071	Human
regulation of catalytic activity	GO:0050790	304	0.071
anatomical structure morphogenesis	GO:0009653	298	0.071	Fly
response to peptide hormone	GO:0043434	278	0.070
negative regulation of protein metabolic process	GO:0051248	114	0.070
regulation of mrna 3 end processing	GO:0031440	1	0.069
negative regulation of transcription dna templated	GO:0045892	116	0.069
protein phosphorylation	GO:0006468	345	0.068
regulation of intracellular signal transduction	GO:1902531	218	0.066
cellular response to nitrogen compound	GO:1901699	210	0.066
nucleobase containing compound catabolic process	GO:0034655	152	0.066
heterocycle catabolic process	GO:0046700	167	0.066
negative regulation of signal transduction	GO:0009968	83	0.065
regulation of cellular amino acid metabolic process	GO:0006521	2	0.065
homeostatic process	GO:0042592	331	0.064
multicellular organism reproduction	GO:0032504	233	0.064	Fly
osteoblast differentiation	GO:0001649	26	0.062
dna metabolic process	GO:0006259	96	0.061
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.060
positive regulation of cellular biosynthetic process	GO:0031328	295	0.060	Human Mouse Fly
negative regulation of cellular biosynthetic process	GO:0031327	161	0.059
negative regulation of protein modification process	GO:0031400	52	0.059
response to radiation	GO:0009314	137	0.058
chemical homeostasis	GO:0048878	292	0.058
regulation of cell differentiation	GO:0045595	320	0.058	Human Mouse
ribonucleotide metabolic process	GO:0009259	231	0.057
organophosphate metabolic process	GO:0019637	370	0.055
cellular nitrogen compound catabolic process	GO:0044270	163	0.055
cellular response to molecule of bacterial origin	GO:0071219	56	0.055	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.054
regulation of p38mapk cascade	GO:1900744	1	0.054
gland development	GO:0048732	155	0.053
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.053
cellular chemical homeostasis	GO:0055082	247	0.053
cellular response to oxidative stress	GO:0034599	76	0.051
multi organism reproductive process	GO:0044703	262	0.051	Fly
negative regulation of gene expression	GO:0010629	199	0.051
mrna stabilization	GO:0048255	2	0.051
metal ion transport	GO:0030001	289	0.049
negative regulation of protein phosphorylation	GO:0001933	44	0.048
positive regulation of cell development	GO:0010720	176	0.047
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.046
regulation of neuron death	GO:1901214	115	0.046
macromolecular complex subunit organization	GO:0043933	339	0.045
mrna 3 end processing	GO:0031124	1	0.045
nucleoside phosphate metabolic process	GO:0006753	283	0.045
regulation of cytokine production	GO:0001817	56	0.045
nucleoside metabolic process	GO:0009116	179	0.044
cellular response to organic cyclic compound	GO:0071407	202	0.044
regulation of cellular catabolic process	GO:0031329	101	0.044
response to oxidative stress	GO:0006979	186	0.043
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.043
regulation of catabolic process	GO:0009894	113	0.043
positive regulation of nervous system development	GO:0051962	178	0.042
positive regulation of cellular component organization	GO:0051130	200	0.041
cellular response to cytokine stimulus	GO:0071345	127	0.041
tumor necrosis factor production	GO:0032640	13	0.040
purine nucleotide catabolic process	GO:0006195	136	0.040
neurological system process	GO:0050877	219	0.039
cellular homeostasis	GO:0019725	252	0.038
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.038
intracellular transport	GO:0046907	185	0.037
head development	GO:0060322	247	0.037
positive regulation of catalytic activity	GO:0043085	184	0.037
circulatory system process	GO:0003013	183	0.037
purine ribonucleotide metabolic process	GO:0009150	227	0.037
positive regulation of neurogenesis	GO:0050769	165	0.036
positive regulation of rna biosynthetic process	GO:1902680	197	0.036	Human Mouse
positive regulation of developmental process	GO:0051094	283	0.036
cation homeostasis	GO:0055080	195	0.035
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.035
single organism reproductive process	GO:0044702	297	0.035	Fly
organonitrogen compound biosynthetic process	GO:1901566	167	0.034	Fly
regulation of protein localization	GO:0032880	81	0.034
negative regulation of developmental process	GO:0051093	125	0.034	Human Mouse
negative regulation of cytokine production	GO:0001818	16	0.034
negative regulation of programmed cell death	GO:0043069	183	0.034
regulation of neuron projection development	GO:0010975	161	0.034
cellular ion homeostasis	GO:0006873	184	0.034
ribose phosphate metabolic process	GO:0019693	235	0.033
positive regulation of signaling	GO:0023056	270	0.033
negative regulation of rna metabolic process	GO:0051253	123	0.033
posttranscriptional regulation of gene expression	GO:0010608	37	0.032
inflammatory response	GO:0006954	150	0.032
response to inorganic substance	GO:0010035	377	0.032
central nervous system development	GO:0007417	311	0.032
regulation of protein kinase activity	GO:0045859	105	0.032
negative regulation of multicellular organismal process	GO:0051241	203	0.032	Mouse
regulation of ion transport	GO:0043269	245	0.031
response to nutrient	GO:0007584	248	0.031
cellular response to acid chemical	GO:0071229	75	0.031
regulation of growth	GO:0040008	105	0.031
dna methylation or demethylation	GO:0044728	8	0.031
erythrocyte differentiation	GO:0030218	1	0.031
nitrogen compound transport	GO:0071705	229	0.030
negative regulation of phosphate metabolic process	GO:0045936	80	0.030
multicellular organism growth	GO:0035264	1	0.030
protein complex subunit organization	GO:0071822	302	0.030
regulation of programmed cell death	GO:0043067	341	0.030
negative regulation of protein kinase activity	GO:0006469	23	0.030
nucleotide metabolic process	GO:0009117	279	0.030
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.029
positive regulation of mrna metabolic process	GO:1903313	4	0.029
organic anion transport	GO:0015711	132	0.029	Rat
response to molecule of bacterial origin	GO:0002237	194	0.029	Mouse
aromatic compound catabolic process	GO:0019439	168	0.029
positive regulation of cell projection organization	GO:0031346	111	0.029
negative regulation of neuron death	GO:1901215	69	0.028
cellular macromolecule catabolic process	GO:0044265	29	0.028
purine containing compound catabolic process	GO:0072523	138	0.028
protein localization	GO:0008104	191	0.028
regulation of multicellular organismal development	GO:2000026	376	0.028	Mouse
organelle organization	GO:0006996	266	0.027
cellular component biogenesis	GO:0044085	368	0.026
amide transport	GO:0042886	105	0.026
purine nucleotide metabolic process	GO:0006163	229	0.026
response to decreased oxygen levels	GO:0036293	237	0.025
regulation of sodium ion transport	GO:0002028	21	0.025
protein complex biogenesis	GO:0070271	263	0.025
regulation of hydrolase activity	GO:0051336	143	0.025
response to other organism	GO:0051707	220	0.025	Mouse Fly
positive regulation of cellular amine metabolic process	GO:0033240	3	0.025
negative regulation of neuron apoptotic process	GO:0043524	45	0.024
sodium ion transport	GO:0006814	82	0.024
positive regulation of cell differentiation	GO:0045597	217	0.024
nucleobase containing small molecule metabolic process	GO:0055086	316	0.024
cytoskeleton organization	GO:0007010	111	0.024
positive regulation of cell proliferation	GO:0008284	249	0.024
rna stabilization	GO:0043489	2	0.024
regulation of neurogenesis	GO:0050767	247	0.024
nucleoside triphosphate catabolic process	GO:0009143	123	0.024
macromolecule localization	GO:0033036	252	0.024
negative regulation of cell proliferation	GO:0008285	119	0.024
anion transport	GO:0006820	178	0.023	Rat
cellular cation homeostasis	GO:0030003	180	0.023
regulation of phosphorus metabolic process	GO:0051174	349	0.023
inactivation of mapk activity	GO:0000188	2	0.023
ion homeostasis	GO:0050801	212	0.023
macromolecule catabolic process	GO:0009057	58	0.023
membrane organization	GO:0061024	94	0.023
positive regulation of neuron projection development	GO:0010976	99	0.023
response to insulin	GO:0032868	133	0.022
single organism intracellular transport	GO:1902582	166	0.022
lipid storage	GO:0019915	1	0.022	Human
negative regulation of collagen biosynthetic process	GO:0032966	4	0.022
nucleoside catabolic process	GO:0009164	126	0.022
nucleoside phosphate catabolic process	GO:1901292	140	0.022
positive regulation of ion transport	GO:0043270	94	0.022
carbohydrate derivative catabolic process	GO:1901136	147	0.022
cellular response to insulin stimulus	GO:0032869	81	0.022
single organism catabolic process	GO:0044712	283	0.022
maintenance of location	GO:0051235	17	0.022
negative regulation of catalytic activity	GO:0043086	103	0.022
brain development	GO:0007420	247	0.022
cell type specific apoptotic process	GO:0097285	134	0.022
regulation of cellular response to stress	GO:0080135	49	0.021
neuron projection development	GO:0031175	273	0.021
organic cyclic compound catabolic process	GO:1901361	175	0.021
regulation of osteoblast differentiation	GO:0045667	14	0.021
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.021
cellular metal ion homeostasis	GO:0006875	172	0.021
regulation of phosphate metabolic process	GO:0019220	349	0.021
cellular response to endogenous stimulus	GO:0071495	377	0.021
behavior	GO:0007610	205	0.020
atp metabolic process	GO:0046034	72	0.020
vasculature development	GO:0001944	70	0.020
rna catabolic process	GO:0006401	3	0.020
positive regulation of catabolic process	GO:0009896	78	0.020
mrna processing	GO:0006397	14	0.020
regulation of cell projection organization	GO:0031344	175	0.020
cytokine mediated signaling pathway	GO:0019221	43	0.020
cellular response to peptide	GO:1901653	133	0.020
response to cytokine	GO:0034097	215	0.020
mammary gland epithelium development	GO:0061180	1	0.020
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019
regulation of neuron differentiation	GO:0045664	208	0.019
cellular sodium ion homeostasis	GO:0006883	4	0.019
regulation of cell morphogenesis	GO:0022604	77	0.019
cytoplasmic transport	GO:0016482	115	0.019
regulation of cell development	GO:0060284	263	0.019
regulation of dendrite development	GO:0050773	59	0.019
cellular protein localization	GO:0034613	122	0.019
positive regulation of mrna catabolic process	GO:0061014	2	0.019
lipid biosynthetic process	GO:0008610	128	0.019
cell projection organization	GO:0030030	302	0.019
regulation of mrna stability	GO:0043488	3	0.019
response to ethanol	GO:0045471	162	0.019
single organism organelle organization	GO:1902589	180	0.018
epithelium development	GO:0060429	96	0.018	Fly
positive regulation of cell death	GO:0010942	184	0.018
proteolysis	GO:0006508	175	0.018
macromolecular complex assembly	GO:0065003	273	0.018
regulation of organelle organization	GO:0033043	80	0.018
memory	GO:0007613	54	0.018
response to growth factor	GO:0070848	189	0.018
negative regulation of cell communication	GO:0010648	158	0.018
epithelial cell differentiation	GO:0030855	71	0.018	Fly
regulation of dna metabolic process	GO:0051052	60	0.017
negative regulation of cell differentiation	GO:0045596	99	0.017	Human Mouse
metal ion homeostasis	GO:0055065	186	0.017
cellular response to steroid hormone stimulus	GO:0071383	93	0.017
regulation of microtubule polymerization or depolymerization	GO:0031110	12	0.017
biological adhesion	GO:0022610	110	0.017
peptidyl tyrosine phosphorylation	GO:0018108	72	0.017
negative regulation of immune system process	GO:0002683	39	0.017	Mouse
regulation of fat cell differentiation	GO:0045598	3	0.017
neuron development	GO:0048666	286	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.017
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.017
negative regulation of innate immune response	GO:0045824	4	0.016
regulation of protein phosphorylation	GO:0001932	183	0.016
negative regulation of transport	GO:0051051	136	0.016
regulation of tumor necrosis factor production	GO:0032680	13	0.016
negative regulation of cellular amine metabolic process	GO:0033239	3	0.016
tumor necrosis factor superfamily cytokine production	GO:0071706	13	0.016
ras protein signal transduction	GO:0007265	29	0.016
cellular response to follicle stimulating hormone stimulus	GO:0071372	13	0.016
regulation of lipid biosynthetic process	GO:0046890	38	0.016
response to reactive oxygen species	GO:0000302	120	0.016
positive regulation of cellular catabolic process	GO:0031331	71	0.016
transmembrane transport	GO:0055085	412	0.016
purine ribonucleoside metabolic process	GO:0046128	168	0.016
regulation of cell growth	GO:0001558	85	0.016
purine containing compound biosynthetic process	GO:0072522	85	0.016
cellular response to tumor necrosis factor	GO:0071356	46	0.016
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.016
reproduction	GO:0000003	245	0.016	Fly
response to metal ion	GO:0010038	253	0.015
negative regulation of ion transport	GO:0043271	51	0.015
regulation of microtubule cytoskeleton organization	GO:0070507	14	0.015
regulation of nervous system development	GO:0051960	264	0.015
response to biotic stimulus	GO:0009607	226	0.015	Mouse Fly
tube development	GO:0035295	89	0.015
positive regulation of neuron differentiation	GO:0045666	126	0.015
response to amine	GO:0014075	46	0.015
nucleoside monophosphate metabolic process	GO:0009123	93	0.015
organophosphate biosynthetic process	GO:0090407	143	0.015
response to tumor necrosis factor	GO:0034612	56	0.015
cellular response to lipid	GO:0071396	201	0.015	Mouse
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	13	0.015
multicellular organismal reproductive process	GO:0048609	233	0.015	Fly
calcium ion transport	GO:0006816	131	0.015
cellular macromolecule localization	GO:0070727	122	0.015
regulation of rna stability	GO:0043487	3	0.015
nucleotide catabolic process	GO:0009166	139	0.014
reactive oxygen species metabolic process	GO:0072593	37	0.014
glycosyl compound metabolic process	GO:1901657	182	0.014
sexual reproduction	GO:0019953	148	0.014	Fly
response to oxygen levels	GO:0070482	265	0.014
growth	GO:0040007	165	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
peptidyl serine phosphorylation	GO:0018105	33	0.014
nucleoside triphosphate metabolic process	GO:0009141	144	0.014
divalent metal ion transport	GO:0070838	132	0.014
negative regulation of tor signaling	GO:0032007	2	0.014
heart process	GO:0003015	57	0.014
positive regulation of hydrolase activity	GO:0051345	86	0.014
cellular response to dna damage stimulus	GO:0006974	19	0.014	Fly
cellular response to hydrogen peroxide	GO:0070301	42	0.014
cellular component movement	GO:0006928	248	0.014
response to carbohydrate	GO:0009743	183	0.014
negative regulation of cellular component organization	GO:0051129	83	0.014
regulation of peptidase activity	GO:0052547	55	0.013
gtp catabolic process	GO:0006184	71	0.013
positive regulation of phosphate metabolic process	GO:0045937	262	0.013
single organism membrane organization	GO:0044802	74	0.013
cell adhesion	GO:0007155	110	0.013
regulation of protein complex assembly	GO:0043254	33	0.013
regulation of stress activated mapk cascade	GO:0032872	23	0.013
reactive oxygen species biosynthetic process	GO:1903409	8	0.013
cellular response to peptide hormone stimulus	GO:0071375	120	0.013
hormone mediated signaling pathway	GO:0009755	23	0.013
small gtpase mediated signal transduction	GO:0007264	36	0.013
response to light stimulus	GO:0009416	52	0.013
regulation of protein transport	GO:0051223	68	0.013
sphingolipid biosynthetic process	GO:0030148	4	0.013
response to axon injury	GO:0048678	59	0.013
developmental process involved in reproduction	GO:0003006	159	0.013	Fly
positive regulation of molecular function	GO:0044093	230	0.013
cellular component assembly	GO:0022607	360	0.013
regulation of nucleotide metabolic process	GO:0006140	117	0.013
hepaticobiliary system development	GO:0061008	90	0.013
dna modification	GO:0006304	12	0.013
guanosine containing compound catabolic process	GO:1901069	71	0.013
interleukin 6 production	GO:0032635	12	0.013
cellular response to glucocorticoid stimulus	GO:0071385	68	0.013
carbohydrate derivative biosynthetic process	GO:1901137	124	0.013
regulation of transferase activity	GO:0051338	123	0.013
negative regulation of transferase activity	GO:0051348	29	0.013
p38mapk cascade	GO:0038066	1	0.012
ribose phosphate biosynthetic process	GO:0046390	87	0.012
steroid metabolic process	GO:0008202	73	0.012
protein import into nucleus	GO:0006606	35	0.012
regulation of cellular localization	GO:0060341	263	0.012
carboxylic acid transport	GO:0046942	115	0.012	Rat
positive regulation of neuron apoptotic process	GO:0043525	33	0.012
spermatogenesis	GO:0007283	99	0.012
organonitrogen compound catabolic process	GO:1901565	179	0.012
regulation of secretion	GO:0051046	224	0.012
response to estradiol	GO:0032355	164	0.012
nucleocytoplasmic transport	GO:0006913	48	0.012
response to mineralocorticoid	GO:0051385	49	0.012
embryo development	GO:0009790	49	0.012
regulation of neuron apoptotic process	GO:0043523	83	0.012
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.012
response to dexamethasone	GO:0071548	49	0.012
positive regulation of mesenchymal cell proliferation	GO:0002053	4	0.012
neuron apoptotic process	GO:0051402	88	0.012
embryonic pattern specification	GO:0009880	1	0.012
response to transition metal nanoparticle	GO:1990267	122	0.012
purine ribonucleotide catabolic process	GO:0009154	136	0.012
regulation of microtubule based process	GO:0032886	14	0.012
positive regulation of g0 to g1 transition	GO:0070318	2	0.012
purine containing compound metabolic process	GO:0072521	253	0.012
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	1	0.012
activation of cysteine type endopeptidase activity	GO:0097202	4	0.012
divalent inorganic cation transport	GO:0072511	134	0.011
regulation of peptidyl tyrosine phosphorylation	GO:0050730	32	0.011
response to acid chemical	GO:0001101	222	0.011
potassium ion transport	GO:0006813	97	0.011
ribonucleoside metabolic process	GO:0009119	174	0.011
protein transport	GO:0015031	132	0.011
divalent inorganic cation homeostasis	GO:0072507	165	0.011
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	3	0.011
cell growth	GO:0016049	104	0.011
glucose metabolic process	GO:0006006	52	0.011
positive regulation of nucleoside metabolic process	GO:0045979	55	0.011
g protein coupled receptor signaling pathway	GO:0007186	242	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
regulation of defense response	GO:0031347	68	0.011	Mouse Fly
wound healing	GO:0042060	122	0.011
cytokine biosynthetic process	GO:0042089	3	0.011
positive regulation of phosphorylation	GO:0042327	177	0.011
response to lipopolysaccharide	GO:0032496	191	0.011	Mouse
positive regulation of cellular protein metabolic process	GO:0032270	167	0.011	Human
ion transmembrane transport	GO:0034220	365	0.011
nucleoside phosphate biosynthetic process	GO:1901293	102	0.011
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.011
reproductive structure development	GO:0048608	128	0.011
regulation of anatomical structure size	GO:0090066	135	0.010
mammary gland development	GO:0030879	38	0.010
organophosphate catabolic process	GO:0046434	148	0.010
photoperiodism	GO:0009648	4	0.010
cellular response to carbohydrate stimulus	GO:0071322	72	0.010
regulation of purine nucleotide metabolic process	GO:1900542	115	0.010
response to vitamin	GO:0033273	131	0.010
secretion	GO:0046903	307	0.010
reactive nitrogen species metabolic process	GO:2001057	1	0.010
regulation of dna methylation	GO:0044030	6	0.010
positive regulation of cell growth	GO:0030307	44	0.010
response to amino acid	GO:0043200	75	0.010
cytosolic calcium ion homeostasis	GO:0051480	140	0.010
multicellular organismal signaling	GO:0035637	44	0.010

Nfkbia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.027
cancer	DOID:162	0.021
organ system cancer	DOID:0050686	0.014
nervous system disease	DOID:863	0.013
disease of anatomical entity	DOID:7	0.013
disease of metabolism	DOID:0014667	0.012

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