Rattus norvegicus

62 known processes

Npr2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

(Aliases: GC-B,NPR-B)

Npr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to endogenous stimulusGO:00714953770.177
positive regulation of developmental processGO:00510942830.123
intracellular signal transductionGO:00355563140.117
Rat
regulation of phosphorus metabolic processGO:00511743490.113
Rat
regulation of signal transductionGO:00099663180.110
cation transportGO:00068123820.108
inorganic ion transmembrane transportGO:00986602290.106
cation transmembrane transportGO:00986552630.103
positive regulation of multicellular organismal processGO:00512403870.100
homeostatic processGO:00425923310.099
regulation of cell proliferationGO:00421273590.096
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.096
Rat
cellular chemical homeostasisGO:00550822470.091
cellular ion homeostasisGO:00068731840.091
metal ion transportGO:00300012890.089
positive regulation of biosynthetic processGO:00098913190.086
Rat
transmembrane transportGO:00550854120.086
cellular homeostasisGO:00197252520.083
organophosphate metabolic processGO:00196373700.078
divalent metal ion transportGO:00708381320.076
single organism catabolic processGO:00447122830.072
cardiovascular system developmentGO:00723581340.064
transcription from rna polymerase ii promoterGO:00063662520.062
catabolic processGO:00090563510.062
inorganic cation transmembrane transportGO:00986622020.060
response to external biotic stimulusGO:00432072210.057
chemical homeostasisGO:00488782920.057
response to oxygen levelsGO:00704822650.057
cation homeostasisGO:00550801950.057
secretionGO:00469033070.056
regulation of phosphate metabolic processGO:00192203490.056
Rat
circulatory system developmentGO:00723591340.054
cellular cation homeostasisGO:00300031800.054
positive regulation of phosphate metabolic processGO:00459372620.054
Rat
blood vessel developmentGO:0001568690.053
response to other organismGO:00517072200.053
neuron projection developmentGO:00311752730.052
positive regulation of cell proliferationGO:00082842490.051
divalent inorganic cation homeostasisGO:00725071650.051
regulation of rna biosynthetic processGO:20011413810.051
immune system processGO:00023762040.050
regulation of rna metabolic processGO:00512523910.050
cellular catabolic processGO:00442482950.049
regulation of transcription dna templatedGO:00063553740.049
cellular metal ion homeostasisGO:00068751720.049
cell projection organizationGO:00300303020.049
rna biosynthetic processGO:00327743800.048
positive regulation of cytosolic calcium ion concentrationGO:00072041220.048
central nervous system developmentGO:00074173110.047
multi organism reproductive processGO:00447032620.047
Mouse
neuron differentiationGO:00301823680.046
single organism biosynthetic processGO:00447113420.046
small molecule biosynthetic processGO:00442831240.046
g protein coupled receptor signaling pathwayGO:00071862420.046
calcium ion homeostasisGO:00550741620.045
nucleotide metabolic processGO:00091172790.045
nucleic acid templated transcriptionGO:00976593790.045
sensory perceptionGO:00076001010.042
Worm
positive regulation of gene expressionGO:00106282440.042
divalent inorganic cation transportGO:00725111340.042
response to carbohydrateGO:00097431830.041
positive regulation of cell differentiationGO:00455972170.041
regulation of catalytic activityGO:00507903040.041
cellular divalent inorganic cation homeostasisGO:00725031620.041
metal ion homeostasisGO:00550651860.040
response to hypoxiaGO:00016662310.040
monovalent inorganic cation transportGO:00156721720.040
carbohydrate derivative metabolic processGO:19011353460.039
nucleobase containing small molecule metabolic processGO:00550863160.039
anatomical structure morphogenesisGO:00096532980.039
organic substance catabolic processGO:19015753160.038
transcription dna templatedGO:00063513770.038
ion homeostasisGO:00508012120.038
response to growth factorGO:00708481890.038
mesoderm developmentGO:000749820.038
brain developmentGO:00074202470.038
alcohol metabolic processGO:0006066770.037
organophosphate catabolic processGO:00464341480.037
ion transmembrane transportGO:00342203650.037
positive regulation of macromolecule biosynthetic processGO:00105572470.037
rna metabolic processGO:00160704060.037
response to monosaccharideGO:00342841590.036
positive regulation of cellular component movementGO:00512721020.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
regulation of protein phosphorylationGO:00019321830.035
regulation of cellular component movementGO:00512701500.035
neuron developmentGO:00486662860.035
cellular response to lipidGO:00713962010.035
response to inorganic substanceGO:00100353770.034
regulation of cell migrationGO:00303341280.033
response to fatty acidGO:0070542650.033
response to glucoseGO:00097491360.033
angiogenesisGO:0001525530.033
regulation of hydrolase activityGO:00513361430.032
oxidation reduction processGO:00551143040.032
embryo developmentGO:0009790490.032
nucleoside phosphate metabolic processGO:00067532830.032
regulation of cellular localizationGO:00603412630.032
anatomical structure formation involved in morphogenesisGO:0048646830.032
regulation of anatomical structure morphogenesisGO:00226031410.031
organonitrogen compound biosynthetic processGO:19015661670.031
head developmentGO:00603222470.031
regulation of membrane potentialGO:00423911100.031
positive regulation of cell communicationGO:00106472710.031
positive regulation of transcription dna templatedGO:00458931970.031
ras protein signal transductionGO:0007265290.031
cellular lipid metabolic processGO:00442552080.031
positive regulation of nitrogen compound metabolic processGO:00511733340.031
Rat
vesicle mediated transportGO:00161921810.031
negative regulation of cellular metabolic processGO:00313242810.031
positive regulation of rna metabolic processGO:00512542030.030
secretion by cellGO:00329402480.030
response to ketoneGO:19016541820.030
organic acid metabolic processGO:00060822920.030
negative regulation of multicellular organismal processGO:00512412030.030
Mouse
regulation of cell projection organizationGO:00313441750.030
regulation of cell differentiationGO:00455953200.030
Mouse
macromolecule localizationGO:00330362520.030
organic hydroxy compound metabolic processGO:19016151150.030
Rat
regulation of multicellular organismal developmentGO:20000263760.029
heart processGO:0003015570.029
learning or memoryGO:0007611900.029
regulation of organ formationGO:000315620.028
single organism reproductive processGO:00447022970.028
Mouse
circulatory system processGO:00030131830.028
response to metal ionGO:00100382530.028
cellular response to hormone stimulusGO:00328702470.028
embryonic appendage morphogenesisGO:003511340.028
cellular component movementGO:00069282480.028
regulation of phosphorylationGO:00423252480.028
potassium ion transportGO:0006813970.028
cellular calcium ion homeostasisGO:00068741600.028
positive regulation of cell migrationGO:0030335960.027
tissue developmentGO:00098882520.027
lipid metabolic processGO:00066292830.027
purine ribonucleotide metabolic processGO:00091502270.027
cytosolic calcium ion homeostasisGO:00514801400.027
immune responseGO:00069551040.027
cellular amine metabolic processGO:0044106380.027
regulation of cell motilityGO:20001451310.027
cellular amino acid metabolic processGO:00065201070.026
muscle system processGO:00030121150.026
response to biotic stimulusGO:00096072260.026
positive regulation of cellular component organizationGO:00511302000.026
multicellular organism reproductionGO:00325042330.026
Mouse
regulation of nervous system developmentGO:00519602640.026
organophosphate biosynthetic processGO:00904071430.025
protein oligomerizationGO:00512591910.025
positive regulation of neurogenesisGO:00507691650.025
regulation of system processGO:00440572080.025
multicellular organismal reproductive processGO:00486092330.025
Mouse
cell cell signalingGO:00072673350.025
negative regulation of cell communicationGO:00106481580.025
purine nucleotide metabolic processGO:00061632290.025
neurological system processGO:00508772190.025
Worm
carboxylic acid metabolic processGO:00197522890.025
cell migrationGO:00164771970.025
muscle cell proliferationGO:0033002840.024
Rat
neuron projection morphogenesisGO:00488121220.024
positive regulation of cellular biosynthetic processGO:00313282950.024
Rat
regulation of protein metabolic processGO:00512462890.024
response to corticosteroidGO:00319602350.024
regulation of ion transmembrane transporter activityGO:0032412480.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
single organism organelle organizationGO:19025891800.024
vasculogenesisGO:000157030.024
localization of cellGO:00516742020.024
regulation of neuron differentiationGO:00456642080.024
positive regulation of nervous system developmentGO:00519621780.024
regulation of neurogenesisGO:00507672470.023
negative regulation of metabolic processGO:00098923310.023
protein complex biogenesisGO:00702712630.023
cellular response to growth factor stimulusGO:00713631620.023
enzyme linked receptor protein signaling pathwayGO:00071671160.023
Human
phospholipid metabolic processGO:0006644610.023
small gtpase mediated signal transductionGO:0007264360.023
calcium ion transportGO:00068161310.023
regulation of molecular functionGO:00650093980.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
apoptotic processGO:00069153810.022
response to oxidative stressGO:00069791860.022
regulation of growthGO:00400081050.022
behaviorGO:00076102050.022
Worm
cell motilityGO:00488702020.022
amine metabolic processGO:0009308380.022
regulation of neuron projection developmentGO:00109751610.022
regulation of intracellular signal transductionGO:19025312180.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
regulation of canonical wnt signaling pathwayGO:006082840.022
response to extracellular stimulusGO:00099913800.022
positive regulation of cell motilityGO:2000147970.021
cellular response to oxygen containing compoundGO:19017013860.021
muscle contractionGO:0006936880.021
positive regulation of immune system processGO:0002684900.021
positive regulation of cell projection organizationGO:00313461110.021
ribonucleotide metabolic processGO:00092592310.021
positive regulation of phosphorus metabolic processGO:00105622620.021
Rat
regulation of cellular protein metabolic processGO:00322682670.021
protein heterooligomerizationGO:0051291890.021
blood circulationGO:00080151830.021
macromolecular complex subunit organizationGO:00439333390.021
positive regulation of signalingGO:00230562700.020
proteolysisGO:00065081750.020
membrane organizationGO:0061024940.020
positive regulation of cellular protein metabolic processGO:00322701670.020
positive regulation of response to stimulusGO:00485842850.020
cellular component morphogenesisGO:00329891550.020
nucleoside phosphate biosynthetic processGO:19012931020.020
purine containing compound metabolic processGO:00725212530.020
reproductive processGO:00224143720.020
Mouse
protein phosphorylationGO:00064683450.020
golgi vesicle transportGO:0048193220.020
cell fate determinationGO:000170920.020
response to mechanical stimulusGO:00096121340.020
regulation of blood circulationGO:19035221100.019
reproductionGO:00000032450.019
Mouse
female pregnancyGO:00075651220.019
cell part morphogenesisGO:00329901230.019
regulation of synaptic transmissionGO:00508041410.019
cellular nitrogen compound catabolic processGO:00442701630.019
locomotionGO:00400112370.018
Worm
calcium ion transmembrane transportGO:0070588700.018
receptor mediated endocytosisGO:0006898420.018
multi multicellular organism processGO:00447061380.018
anterior posterior pattern specificationGO:000995210.018
regulation of immune responseGO:0050776550.018
biological adhesionGO:00226101100.018
regulation of cellular amino acid metabolic processGO:000652120.018
response to molecule of bacterial originGO:00022371940.018
negative regulation of transportGO:00510511360.018
negative regulation of innate immune responseGO:004582440.018
regulation of cellular component organizationGO:00511283680.017
synaptic transmissionGO:00072682350.017
heart contractionGO:0060047570.017
response to hyperoxiaGO:0055093450.017
single organism behaviorGO:00447081300.017
Worm
negative regulation of cell deathGO:00605482290.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
response to decreased oxygen levelsGO:00362932370.017
reactive oxygen species metabolic processGO:0072593370.017
negative regulation of signalingGO:00230571570.017
programmed cell deathGO:00125013920.017
forebrain developmentGO:0030900980.017
positive regulation of rna biosynthetic processGO:19026801970.017
heterocycle catabolic processGO:00467001670.017
positive regulation of mapk cascadeGO:0043410920.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
organelle organizationGO:00069962660.017
positive regulation of signal transductionGO:00099671750.017
limb morphogenesisGO:003510840.017
response to woundingGO:00096112540.016
chemotaxisGO:0006935660.016
Worm
taxisGO:0042330670.016
Worm
ribose phosphate metabolic processGO:00196932350.016
negative regulation of signal transductionGO:0009968830.016
positive regulation of phosphorylationGO:00423271770.016
positive regulation of protein modification processGO:00314011420.016
intracellular transportGO:00469071850.016
nitrogen compound transportGO:00717052290.016
macromolecular complex assemblyGO:00650032730.016
vascular process in circulatory systemGO:0003018960.016
glycerolipid metabolic processGO:0046486670.016
organonitrogen compound catabolic processGO:19015651790.016
cell growthGO:00160491040.016
response to glucocorticoidGO:00513842230.016
endocytosisGO:0006897840.016
cellular potassium ion transportGO:0071804720.016
regulation of secretion by cellGO:19035302080.015
tissue regenerationGO:0042246360.015
smooth muscle cell proliferationGO:0048659770.015
Rat
negative regulation of response to stimulusGO:00485851550.015
positive regulation of transportGO:00510502450.015
urogenital system developmentGO:0001655780.015
regulation of cell developmentGO:00602842630.015
Mouse
developmental process involved in reproductionGO:00030061590.015
Mouse
response to acid chemicalGO:00011012220.015
angioblast cell migrationGO:003547610.015
negative regulation of macromolecule metabolic processGO:00106052600.015
protein localizationGO:00081041910.015
positive regulation of immunoglobulin productionGO:000263940.015
oxoacid metabolic processGO:00434362900.015
response to lipopolysaccharideGO:00324961910.015
organic cyclic compound catabolic processGO:19013611750.015
negative regulation of biosynthetic processGO:00098901680.015
cellular macromolecule localizationGO:00707271220.015
rhythmic processGO:00485111560.015
response to peptide hormoneGO:00434342780.015
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.014
regulation of purine nucleotide metabolic processGO:19005421150.014
Rat
positive regulation of neuron differentiationGO:00456661260.014
protein complex subunit organizationGO:00718223020.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
cell projection morphogenesisGO:00488581230.014
bmp signaling pathwayGO:003050940.014
regulation of apoptotic processGO:00429813350.014
response to hexoseGO:00097461440.014
carbohydrate derivative biosynthetic processGO:19011371240.014
defense responseGO:00069521940.014
positive regulation of protein metabolic processGO:00512471780.014
positive regulation of intracellular signal transductionGO:19025331380.014
positive regulation of isotype switchingGO:004583010.014
regulation of immune system processGO:00026821230.014
heart developmentGO:0007507720.014
carbohydrate derivative catabolic processGO:19011361470.014
regulation of cell growthGO:0001558850.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
defense response to gram negative bacteriumGO:005082930.014
regulation of g0 to g1 transitionGO:007031630.014
muscle cell differentiationGO:0042692520.013
positive regulation of molecular functionGO:00440932300.013
positive regulation of cell developmentGO:00107201760.013
mapk cascadeGO:00001651400.013
response to tumor necrosis factorGO:0034612560.013
regulation of blood vessel sizeGO:0050880890.013
regulation of locomotionGO:00400121480.013
glycerophospholipid metabolic processGO:0006650470.013
rho protein signal transductionGO:0007266110.013
regulation of heart contractionGO:0008016480.013
regulation of metal ion transportGO:00109591180.013
regulation of programmed cell deathGO:00430673410.013
single organism carbohydrate metabolic processGO:00447231180.013
response to calcium ionGO:0051592590.013
organic hydroxy compound biosynthetic processGO:1901617510.013
regulation of blood vessel endothelial cell migrationGO:004353540.013
regulation of endothelial cell differentiationGO:004560140.013
regulation of tube sizeGO:0035150890.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
cellular response to organic cyclic compoundGO:00714072020.013
nucleotide catabolic processGO:00091661390.013
regulation of mapk cascadeGO:00434081160.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.013
positive regulation of neuron projection developmentGO:0010976990.013
positive regulation of cellular amine metabolic processGO:003324030.013
dendrite developmentGO:0016358720.013
glycogen metabolic processGO:0005977230.012
neural crest cell developmentGO:001403220.012
negative regulation of neurogenesisGO:0050768780.012
positive regulation of immune responseGO:0050778420.012
positive regulation of cellular component biogenesisGO:0044089550.012
positive regulation of secretionGO:00510471400.012
response to nutrient levelsGO:00316673700.012
vasculature developmentGO:0001944700.012
potassium ion transmembrane transportGO:0071805710.012
signal transduction by phosphorylationGO:00230141440.012
sexual reproductionGO:00199531480.012
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
negative regulation of cell proliferationGO:00082851190.012
Rat
axis specificationGO:000979840.012
cardiac chamber developmentGO:000320510.012
detection of stimulusGO:0051606240.012
response to bacteriumGO:00096172000.012
carbohydrate homeostasisGO:0033500750.012
cellular response to nitrogen compoundGO:19016992100.012
memoryGO:0007613540.012
regulation of cellular amine metabolic processGO:003323880.012
embryonic limb morphogenesisGO:003032640.012
protein tetramerizationGO:0051262380.012
second messenger mediated signalingGO:0019932510.012
cellular response to tumor necrosis factorGO:0071356460.012
regulation of ion transmembrane transportGO:00347651210.012
cell proliferation in forebrainGO:002184630.011
nucleobase containing compound catabolic processGO:00346551520.011
protein complex assemblyGO:00064612630.011
cellular component biogenesisGO:00440853680.011
regulation of phagocytosis engulfmentGO:006009940.011
cardiac ventricle developmentGO:000323110.011
positive regulation of hydrolase activityGO:0051345860.011
somatic stem cell maintenanceGO:003501920.011
cognitionGO:0050890920.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
stem cell divisionGO:001714540.011
regulation of cell morphogenesisGO:0022604770.011
detection of chemical stimulusGO:0009593100.011
response to cytokineGO:00340972150.011
Human
purine nucleotide biosynthetic processGO:0006164830.011
positive regulation of endothelial cell differentiationGO:004560320.011
regulation of cellular ketone metabolic processGO:0010565270.011
reproductive structure developmentGO:00486081280.011
sex differentiationGO:00075481130.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
positive regulation of catalytic activityGO:00430851840.011
response to radiationGO:00093141370.011
negative regulation of apoptotic processGO:00430661810.011
cell type specific apoptotic processGO:00972851340.011
response to estrogenGO:00436272320.011
response to alkaloidGO:00432791320.011
reproductive system developmentGO:00614581280.011
cytoplasmic transportGO:00164821150.011
membrane depolarizationGO:0051899320.010
response to organophosphorusGO:00466831020.010
regulation of catabolic processGO:00098941130.010
inner ear receptor cell differentiationGO:006011320.010
reactive oxygen species biosynthetic processGO:190340980.010
gamete generationGO:00072761240.010
Mouse
negative regulation of programmed cell deathGO:00430691830.010
sensory perception of bitter tasteGO:005091340.010
negative regulation of molecular functionGO:00440921330.010
gastrulationGO:000736920.010
striated muscle contractionGO:0006941440.010
organ senescenceGO:001026020.010
cyclic nucleotide metabolic processGO:0009187800.010
muscle structure developmentGO:0061061870.010

Npr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.020
Human
disease of anatomical entityDOID:700.020
Human
cardiovascular system diseaseDOID:128700.016
gastrointestinal system diseaseDOID:7700.013
nervous system diseaseDOID:86300.012