IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Znf746

zinc finger protein 746

(Aliases: RGD1306209,Zfp746)

RGD: 1306209
Ensembl: ENSRNOG00000007064
Entrez: 312303
UniProtKB: F1LSG4

Process Predictions
Disease Predictions

Znf746 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cellular localization	GO:0060341	263	0.193
regulation of secretion	GO:0051046	224	0.127
regulation of rna metabolic process	GO:0051252	391	0.121	Mouse
cellular ketone metabolic process	GO:0042180	51	0.106
cellular metal ion homeostasis	GO:0006875	172	0.104
oxoacid metabolic process	GO:0043436	290	0.100
negative regulation of macromolecule metabolic process	GO:0010605	260	0.085	Mouse
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.083
regulation of rna biosynthetic process	GO:2001141	381	0.081	Mouse
regulation of nucleic acid templated transcription	GO:1903506	380	0.080	Mouse
regulation of phosphorus metabolic process	GO:0051174	349	0.074
organic acid metabolic process	GO:0006082	292	0.072
organophosphate metabolic process	GO:0019637	370	0.072
positive regulation of signaling	GO:0023056	270	0.068
nucleic acid templated transcription	GO:0097659	379	0.067	Mouse
protein phosphorylation	GO:0006468	345	0.064
regulation of cellular component organization	GO:0051128	368	0.060
single organism biosynthetic process	GO:0044711	342	0.060
cellular amino acid metabolic process	GO:0006520	107	0.060
lipid metabolic process	GO:0006629	283	0.059
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.059
regulation of multicellular organismal development	GO:2000026	376	0.058
regulation of phosphate metabolic process	GO:0019220	349	0.058
neuron projection development	GO:0031175	273	0.057
regulation of secretion by cell	GO:1903530	208	0.057
regulation of protein metabolic process	GO:0051246	289	0.056
regulation of phosphorylation	GO:0042325	248	0.056
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.055	Mouse
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.054	Mouse
regulation of molecular function	GO:0065009	398	0.054
metal ion transport	GO:0030001	289	0.054
divalent inorganic cation transport	GO:0072511	134	0.054
carboxylic acid metabolic process	GO:0019752	289	0.054
positive regulation of secretion by cell	GO:1903532	128	0.053
protein heterooligomerization	GO:0051291	89	0.052
regulation of hormone levels	GO:0010817	187	0.052
regulation of cellular amine metabolic process	GO:0033238	8	0.051
positive regulation of transport	GO:0051050	245	0.050
transcription dna templated	GO:0006351	377	0.048	Mouse
amine metabolic process	GO:0009308	38	0.048
regulation of cellular protein metabolic process	GO:0032268	267	0.047
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.046
regulation of nervous system development	GO:0051960	264	0.046
regulation of cell proliferation	GO:0042127	359	0.046
lipid biosynthetic process	GO:0008610	128	0.045
cytosolic calcium ion homeostasis	GO:0051480	140	0.045
negative regulation of metabolic process	GO:0009892	331	0.044	Mouse
neuron differentiation	GO:0030182	368	0.044
regulation of cellular ketone metabolic process	GO:0010565	27	0.044
positive regulation of phosphorylation	GO:0042327	177	0.043
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.043	Mouse
neuron development	GO:0048666	286	0.043
nucleobase containing small molecule metabolic process	GO:0055086	316	0.042
secretion by cell	GO:0032940	248	0.042
divalent metal ion transport	GO:0070838	132	0.042
tissue development	GO:0009888	252	0.041
cellular ion homeostasis	GO:0006873	184	0.041
cellular amine metabolic process	GO:0044106	38	0.041
carbohydrate derivative metabolic process	GO:1901135	346	0.041
cellular response to organonitrogen compound	GO:0071417	197	0.040
calcium ion homeostasis	GO:0055074	162	0.039
central nervous system development	GO:0007417	311	0.039
negative regulation of response to stimulus	GO:0048585	155	0.039
cellular calcium ion homeostasis	GO:0006874	160	0.038
regulation of signal transduction	GO:0009966	318	0.038
single organism reproductive process	GO:0044702	297	0.037
regulation of blood pressure	GO:0008217	83	0.037
intracellular signal transduction	GO:0035556	314	0.037
regulation of hormone secretion	GO:0046883	106	0.037
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.036
purine ribonucleotide metabolic process	GO:0009150	227	0.036
single organism intracellular transport	GO:1902582	166	0.036
cation transport	GO:0006812	382	0.035
response to nutrient levels	GO:0031667	370	0.035
negative regulation of cellular metabolic process	GO:0031324	281	0.035	Mouse
cellular response to lipid	GO:0071396	201	0.034
regulation of cellular amino acid metabolic process	GO:0006521	2	0.034
positive regulation of secretion	GO:0051047	140	0.034
cation homeostasis	GO:0055080	195	0.034
ion homeostasis	GO:0050801	212	0.034
intracellular transport	GO:0046907	185	0.033
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.033	Mouse
regulation of transferase activity	GO:0051338	123	0.032
cellular response to oxygen containing compound	GO:1901701	386	0.032
chemical homeostasis	GO:0048878	292	0.032
regulation of neuron differentiation	GO:0045664	208	0.032
cellular chemical homeostasis	GO:0055082	247	0.032
regulation of protein modification process	GO:0031399	194	0.032
secretion	GO:0046903	307	0.032
protein complex assembly	GO:0006461	263	0.031
regulation of cell differentiation	GO:0045595	320	0.031
rna metabolic process	GO:0016070	406	0.031	Mouse
small molecule biosynthetic process	GO:0044283	124	0.031
positive regulation of cell proliferation	GO:0008284	249	0.030
positive regulation of multicellular organismal process	GO:0051240	387	0.030
rna biosynthetic process	GO:0032774	380	0.030	Mouse
positive regulation of phosphorus metabolic process	GO:0010562	262	0.029
regulation of transcription dna templated	GO:0006355	374	0.029	Mouse
macromolecule localization	GO:0033036	252	0.028
positive regulation of gene expression	GO:0010628	244	0.028
positive regulation of cell communication	GO:0010647	271	0.028
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.028	Mouse
regulation of cell development	GO:0060284	263	0.028
positive regulation of phosphate metabolic process	GO:0045937	262	0.028
amide transport	GO:0042886	105	0.028
response to extracellular stimulus	GO:0009991	380	0.027
regulation of protein phosphorylation	GO:0001932	183	0.027
purine containing compound metabolic process	GO:0072521	253	0.027
response to estrogen	GO:0043627	232	0.027
cellular lipid metabolic process	GO:0044255	208	0.027
negative regulation of multicellular organismal process	GO:0051241	203	0.027
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.027
divalent inorganic cation homeostasis	GO:0072507	165	0.027
steroid metabolic process	GO:0008202	73	0.026
regulation of neurogenesis	GO:0050767	247	0.026
regulation of response to external stimulus	GO:0032101	106	0.026
regulation of protein kinase activity	GO:0045859	105	0.026
cellular component morphogenesis	GO:0032989	155	0.026
protein complex subunit organization	GO:0071822	302	0.026
multicellular organismal reproductive process	GO:0048609	233	0.026
organophosphate biosynthetic process	GO:0090407	143	0.026
positive regulation of signal transduction	GO:0009967	175	0.026
organonitrogen compound biosynthetic process	GO:1901566	167	0.025
protein complex biogenesis	GO:0070271	263	0.025
hormone secretion	GO:0046879	115	0.025
nucleoside phosphate biosynthetic process	GO:1901293	102	0.024
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.024
reproductive structure development	GO:0048608	128	0.024
developmental process involved in reproduction	GO:0003006	159	0.024
response to inorganic substance	GO:0010035	377	0.024
mapk cascade	GO:0000165	140	0.024
negative regulation of transcription dna templated	GO:0045892	116	0.024	Mouse
homeostatic process	GO:0042592	331	0.024
positive regulation of peptide secretion	GO:0002793	52	0.024
cellular component assembly	GO:0022607	360	0.024
regulation of intracellular signal transduction	GO:1902531	218	0.023
regulation of peptide secretion	GO:0002791	82	0.023
cellular cation homeostasis	GO:0030003	180	0.023
cell projection organization	GO:0030030	302	0.023
reproductive process	GO:0022414	372	0.023
transcription from rna polymerase ii promoter	GO:0006366	252	0.023	Mouse
regulation of kinase activity	GO:0043549	117	0.023
metal ion homeostasis	GO:0055065	186	0.022
nucleotide metabolic process	GO:0009117	279	0.022
signal release	GO:0023061	145	0.022
positive regulation of rna biosynthetic process	GO:1902680	197	0.022
neuron projection morphogenesis	GO:0048812	122	0.022
regulation of cell projection organization	GO:0031344	175	0.022
regulation of peptide hormone secretion	GO:0090276	80	0.022
hormone transport	GO:0009914	121	0.022
protein transport	GO:0015031	132	0.022
regulation of catalytic activity	GO:0050790	304	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.022
peptide secretion	GO:0002790	86	0.021
reproduction	GO:0000003	245	0.021
positive regulation of response to stimulus	GO:0048584	285	0.021
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.021
negative regulation of signal transduction	GO:0009968	83	0.021
head development	GO:0060322	247	0.021
phosphatidylinositol dephosphorylation	GO:0046856	4	0.021
regulation of peptide transport	GO:0090087	87	0.021
cellular protein localization	GO:0034613	122	0.020
anatomical structure morphogenesis	GO:0009653	298	0.020
negative regulation of cellular biosynthetic process	GO:0031327	161	0.020	Mouse
eye morphogenesis	GO:0048592	4	0.020
organic hydroxy compound biosynthetic process	GO:1901617	51	0.020
defense response	GO:0006952	194	0.020
protein localization	GO:0008104	191	0.020
asymmetric protein localization	GO:0008105	2	0.020
cellular homeostasis	GO:0019725	252	0.020
peptide hormone secretion	GO:0030072	84	0.020
negative regulation of biosynthetic process	GO:0009890	168	0.020	Mouse
response to calcium ion	GO:0051592	59	0.019
cellular response to growth factor stimulus	GO:0071363	162	0.019
positive regulation of peptide hormone secretion	GO:0090277	50	0.019
positive regulation of biosynthetic process	GO:0009891	319	0.019
growth	GO:0040007	165	0.019
catabolic process	GO:0009056	351	0.019
negative regulation of molecular function	GO:0044092	133	0.019
inflammatory response	GO:0006954	150	0.019
positive regulation of developmental process	GO:0051094	283	0.019
nucleoside phosphate metabolic process	GO:0006753	283	0.019
regulation of neuron projection development	GO:0010975	161	0.018
response to growth factor	GO:0070848	189	0.018
cellular response to endogenous stimulus	GO:0071495	377	0.018
axis specification	GO:0009798	4	0.018
response to wounding	GO:0009611	254	0.018
positive regulation of cellular biosynthetic process	GO:0031328	295	0.018
positive regulation of intracellular signal transduction	GO:1902533	138	0.018
peptidyl tyrosine phosphorylation	GO:0018108	72	0.018
positive regulation of neurogenesis	GO:0050769	165	0.018
organelle organization	GO:0006996	266	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.018
purine nucleotide metabolic process	GO:0006163	229	0.017
regulation of ion transport	GO:0043269	245	0.017
ion transmembrane transport	GO:0034220	365	0.017
embryonic pattern specification	GO:0009880	1	0.017
positive regulation of cellular amine metabolic process	GO:0033240	3	0.017
carbohydrate derivative biosynthetic process	GO:1901137	124	0.017
ribose phosphate metabolic process	GO:0019693	235	0.017
ras protein signal transduction	GO:0007265	29	0.017
positive regulation of transcription dna templated	GO:0045893	197	0.017
gland development	GO:0048732	155	0.017
response to glucose	GO:0009749	136	0.017
regulation of protein localization	GO:0032880	81	0.017
positive regulation of protein phosphorylation	GO:0001934	135	0.017
alpha amino acid metabolic process	GO:1901605	71	0.016
response to metal ion	GO:0010038	253	0.016
regulation of mapk cascade	GO:0043408	116	0.016
reproductive system development	GO:0061458	128	0.016
positive regulation of cell development	GO:0010720	176	0.016
negative regulation of transport	GO:0051051	136	0.016
development of primary female sexual characteristics	GO:0046545	56	0.016
positive regulation of molecular function	GO:0044093	230	0.016
camera type eye morphogenesis	GO:0048593	2	0.016
cell morphogenesis involved in differentiation	GO:0000904	119	0.016
steroid biosynthetic process	GO:0006694	48	0.016
positive regulation of catalytic activity	GO:0043085	184	0.016
response to peptide hormone	GO:0043434	278	0.015
signal transduction by phosphorylation	GO:0023014	144	0.015
regulation of establishment of protein localization	GO:0070201	69	0.015
response to ketone	GO:1901654	182	0.015
female sex differentiation	GO:0046660	59	0.015
response to vitamin	GO:0033273	131	0.015
response to decreased oxygen levels	GO:0036293	237	0.015
response to oxygen levels	GO:0070482	265	0.015
proteolysis	GO:0006508	175	0.015
response to hexose	GO:0009746	144	0.015
muscle structure development	GO:0061061	87	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.015	Mouse
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.015
cellular response to alcohol	GO:0097306	87	0.015
cellular catabolic process	GO:0044248	295	0.015
negative regulation of protein metabolic process	GO:0051248	114	0.014
dna metabolic process	GO:0006259	96	0.014
regulation of metal ion transport	GO:0010959	118	0.014
cyclic nucleotide metabolic process	GO:0009187	80	0.014
muscle cell proliferation	GO:0033002	84	0.014
positive regulation of cellular protein metabolic process	GO:0032270	167	0.014
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.014
cell morphogenesis	GO:0000902	142	0.014
positive regulation of rna metabolic process	GO:0051254	203	0.014
regulation of lipid metabolic process	GO:0019216	68	0.014
regulation of smooth muscle cell proliferation	GO:0048660	75	0.014
macromolecular complex assembly	GO:0065003	273	0.014
glycerolipid metabolic process	GO:0046486	67	0.014
programmed cell death	GO:0012501	392	0.014
regulation of programmed cell death	GO:0043067	341	0.014
detection of calcium ion	GO:0005513	1	0.014
cellular response to hormone stimulus	GO:0032870	247	0.013
single organism behavior	GO:0044708	130	0.013
cell projection morphogenesis	GO:0048858	123	0.013
negative regulation of response to external stimulus	GO:0032102	37	0.013
aging	GO:0007568	241	0.013
organic substance catabolic process	GO:1901575	316	0.013
wound healing	GO:0042060	122	0.013
vesicle mediated transport	GO:0016192	181	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.013
purine nucleotide biosynthetic process	GO:0006164	83	0.013
negative regulation of cell communication	GO:0010648	158	0.013
positive regulation of protein metabolic process	GO:0051247	178	0.013
brain development	GO:0007420	247	0.013
transmembrane transport	GO:0055085	412	0.013
regulation of calcium ion transport	GO:0051924	77	0.013
sex differentiation	GO:0007548	113	0.013
response to peptide	GO:1901652	292	0.013
blood circulation	GO:0008015	183	0.013
response to insulin	GO:0032868	133	0.013
monocarboxylic acid metabolic process	GO:0032787	152	0.013
regulation of insulin secretion	GO:0050796	65	0.012
negative regulation of signaling	GO:0023057	157	0.012
positive regulation of cell differentiation	GO:0045597	217	0.012
alcohol metabolic process	GO:0006066	77	0.012
cytoplasmic transport	GO:0016482	115	0.012
hormone mediated signaling pathway	GO:0009755	23	0.012
regulation of protein transport	GO:0051223	68	0.012
negative regulation of catalytic activity	GO:0043086	103	0.012
centrosome organization	GO:0051297	1	0.012
multi organism reproductive process	GO:0044703	262	0.012
single organism catabolic process	GO:0044712	283	0.012
oxidation reduction process	GO:0055114	304	0.012
camp metabolic process	GO:0046058	63	0.012
regulation of intracellular transport	GO:0032386	65	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.012
regulation of cell growth	GO:0001558	85	0.012
multicellular organism growth	GO:0035264	1	0.012
negative regulation of cellular component organization	GO:0051129	83	0.012
positive regulation of protein modification process	GO:0031401	142	0.011
insulin secretion	GO:0030073	69	0.011
single organism organelle organization	GO:1902589	180	0.011
response to dexamethasone	GO:0071548	49	0.011
gonad development	GO:0008406	104	0.011
regulation of membrane potential	GO:0042391	110	0.011
response to acid chemical	GO:0001101	222	0.011
cell activation	GO:0001775	97	0.011
cell motility	GO:0048870	202	0.011
cellular response to peptide	GO:1901653	133	0.011
peptidyl amino acid modification	GO:0018193	126	0.011
phospholipid metabolic process	GO:0006644	61	0.011
negative regulation of cell development	GO:0010721	82	0.011
response to cytokine	GO:0034097	215	0.011
positive regulation of transferase activity	GO:0051347	81	0.011
development of primary sexual characteristics	GO:0045137	107	0.011
cellular macromolecule localization	GO:0070727	122	0.011
ribonucleoside metabolic process	GO:0009119	174	0.011
glucose homeostasis	GO:0042593	75	0.011
spindle organization	GO:0007051	2	0.011
g protein coupled receptor signaling pathway	GO:0007186	242	0.011
gastrulation	GO:0007369	2	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
ribonucleotide biosynthetic process	GO:0009260	85	0.011
regulation of nucleocytoplasmic transport	GO:0046822	28	0.011
regulation of mrna splicing via spliceosome	GO:0048024	3	0.011
calcium ion transport	GO:0006816	131	0.011
cellular component movement	GO:0006928	248	0.011
positive regulation of ion transport	GO:0043270	94	0.011
salivary gland development	GO:0007431	3	0.010
response to amine	GO:0014075	46	0.010
positive regulation of nucleotide metabolic process	GO:0045981	91	0.010
response to oxidative stress	GO:0006979	186	0.010
protein oligomerization	GO:0051259	191	0.010
macromolecular complex subunit organization	GO:0043933	339	0.010
ribose phosphate biosynthetic process	GO:0046390	87	0.010
establishment of protein localization	GO:0045184	141	0.010
retina morphogenesis in camera type eye	GO:0060042	1	0.010
inorganic ion transmembrane transport	GO:0098660	229	0.010
cell cell signaling	GO:0007267	335	0.010
phasic smooth muscle contraction	GO:0014821	3	0.010
positive regulation of amine transport	GO:0051954	26	0.010
protein localization to organelle	GO:0033365	57	0.010
regulation of anatomical structure size	GO:0090066	135	0.010
positive regulation of nervous system development	GO:0051962	178	0.010

Znf746 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.016
disease of anatomical entity	DOID:7	0.016
nervous system disease	DOID:863	0.014
sensory system disease	DOID:0050155	0.014
eye disease	DOID:5614	0.014
eye and adnexa disease	DOID:1492	0.014
retinal disease	DOID:5679	0.013
disease of cellular proliferation	DOID:14566	0.012

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