Rattus norvegicus

15 known processes

S1pr2

sphingosine-1-phosphate receptor 2

(Aliases: H218,Edg5,Gpcr13,snGPCR18,GPCR18)

S1pr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component movementGO:00069282480.766
enzyme linked receptor protein signaling pathwayGO:00071671160.741
cellular response to endogenous stimulusGO:00714953770.716
regulation of secretionGO:00510462240.647
locomotionGO:00400112370.637
positive regulation of locomotionGO:00400171020.550
regulation of cellular localizationGO:00603412630.540
regulation of protein modification processGO:00313991940.528
regulation of cellular component movementGO:00512701500.519
positive regulation of secretionGO:00510471400.505
protein complex biogenesisGO:00702712630.495
response to estrogenGO:00436272320.476
cell motilityGO:00488702020.472
regulation of cell motilityGO:20001451310.472
response to estradiolGO:00323551640.464
regulation of locomotionGO:00400121480.463
response to external biotic stimulusGO:00432072210.461
cell migrationGO:00164771970.460
positive regulation of cell motilityGO:2000147970.455
wound healingGO:00420601220.454
intracellular signal transductionGO:00355563140.447
regulation of phosphate metabolic processGO:00192203490.439
cellular component biogenesisGO:00440853680.436
cell morphogenesisGO:00009021420.425
regulation of cell migrationGO:00303341280.408
regulation of molecular functionGO:00650093980.403
regulation of cellular component organizationGO:00511283680.403
anatomical structure morphogenesisGO:00096532980.402
response to cytokineGO:00340972150.400
single organism biosynthetic processGO:00447113420.398
positive regulation of cellular component movementGO:00512721020.397
response to oxygen levelsGO:00704822650.397
positive regulation of cell migrationGO:0030335960.386
defense responseGO:00069521940.384
positive regulation of phosphate metabolic processGO:00459372620.378
regulation of cell proliferationGO:00421273590.378
response to corticosteroidGO:00319602350.375
response to woundingGO:00096112540.372
tissue developmentGO:00098882520.370
positive regulation of response to stimulusGO:00485842850.347
protein complex assemblyGO:00064612630.343
response to biotic stimulusGO:00096072260.343
cellular cation homeostasisGO:00300031800.340
regulation of transcription dna templatedGO:00063553740.338
response to glucocorticoidGO:00513842230.338
regulation of intracellular signal transductionGO:19025312180.336
regulation of signal transductionGO:00099663180.335
positive regulation of signal transductionGO:00099671750.335
positive regulation of transportGO:00510502450.333
cellular component morphogenesisGO:00329891550.332
regulation of phosphorus metabolic processGO:00511743490.321
response to bacteriumGO:00096172000.316
macromolecule localizationGO:00330362520.316
macromolecular complex assemblyGO:00650032730.306
regulation of body fluid levelsGO:0050878900.306
cellular component assemblyGO:00226073600.300
cell projection morphogenesisGO:00488581230.297
macromolecular complex subunit organizationGO:00439333390.296
inflammatory responseGO:00069541500.295
regulation of response to stressGO:00801341260.295
lipid metabolic processGO:00066292830.294
carbohydrate derivative metabolic processGO:19011353460.289
cell cell signalingGO:00072673350.287
response to inorganic substanceGO:00100353770.286
response to other organismGO:00517072200.284
positive regulation of phosphorus metabolic processGO:00105622620.282
negative regulation of multicellular organismal processGO:00512412030.280
localization of cellGO:00516742020.277
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.275
regulation of anatomical structure morphogenesisGO:00226031410.274
protein phosphorylationGO:00064683450.273
positive regulation of protein metabolic processGO:00512471780.272
transcription dna templatedGO:00063513770.272
cellular ion homeostasisGO:00068731840.271
cell projection organizationGO:00300303020.270
mapk cascadeGO:00001651400.268
regulation of apoptotic processGO:00429813350.264
regulation of protein metabolic processGO:00512462890.262
cation homeostasisGO:00550801950.258
response to growth factorGO:00708481890.258
positive regulation of cellular protein metabolic processGO:00322701670.257
protein complex subunit organizationGO:00718223020.256
positive regulation of biosynthetic processGO:00098913190.256
response to peptideGO:19016522920.256
response to peptide hormoneGO:00434342780.252
protein secretionGO:0009306340.251
regulation of phosphorylationGO:00423252480.250
organophosphate catabolic processGO:00464341480.245
monovalent inorganic cation transportGO:00156721720.244
cation transportGO:00068123820.242
response to ionizing radiationGO:0010212590.239
response to hypoxiaGO:00016662310.237
cellular response to stressGO:00335542690.232
protein oligomerizationGO:00512591910.229
cellular calcium ion homeostasisGO:00068741600.228
secretion by cellGO:00329402480.225
regulation of secretion by cellGO:19035302080.215
response to heatGO:0009408600.213
negative regulation of metabolic processGO:00098923310.212
reproductive processGO:00224143720.212
growthGO:00400071650.209
neuron projection developmentGO:00311752730.209
cellular metal ion homeostasisGO:00068751720.207
cytosolic calcium ion homeostasisGO:00514801400.207
cytokine productionGO:0001816610.204
nucleic acid templated transcriptionGO:00976593790.201
positive regulation of signalingGO:00230562700.195
homeostatic processGO:00425923310.195
regulation of response to woundingGO:1903034690.188
secretionGO:00469033070.186
rna metabolic processGO:00160704060.185
digestive system developmentGO:0055123410.182
positive regulation of cell proliferationGO:00082842490.181
regulation of immune system processGO:00026821230.181
g protein coupled receptor signaling pathwayGO:00071862420.181
regulation of catalytic activityGO:00507903040.180
positive regulation of protein modification processGO:00314011420.180
response to molecule of bacterial originGO:00022371940.179
positive regulation of nitrogen compound metabolic processGO:00511733340.177
calcium ion homeostasisGO:00550741620.177
positive regulation of cellular biosynthetic processGO:00313282950.176
muscle system processGO:00030121150.176
neuron projection morphogenesisGO:00488121220.175
regenerationGO:00310991630.174
reproductive system developmentGO:00614581280.173
positive regulation of protein phosphorylationGO:00019341350.173
metal ion homeostasisGO:00550651860.173
response to ketoneGO:19016541820.172
signal transduction by phosphorylationGO:00230141440.170
regulation of multicellular organismal developmentGO:20000263760.169
positive regulation of gene expressionGO:00106282440.167
positive regulation of immune system processGO:0002684900.167
metal ion transportGO:00300012890.166
regulation of cellular protein metabolic processGO:00322682670.164
nucleoside metabolic processGO:00091161790.161
cellular chemical homeostasisGO:00550822470.161
cellular homeostasisGO:00197252520.154
tissue remodelingGO:0048771400.152
positive regulation of phosphorylationGO:00423271770.152
organic substance catabolic processGO:19015753160.150
positive regulation of secretion by cellGO:19035321280.148
anatomical structure formation involved in morphogenesisGO:0048646830.146
regulation of protein phosphorylationGO:00019321830.146
single organism reproductive processGO:00447022970.146
negative regulation of macromolecule metabolic processGO:00106052600.144
regulation of nucleic acid templated transcriptionGO:19035063800.144
organonitrogen compound catabolic processGO:19015651790.143
gland developmentGO:00487321550.143
response to oxidative stressGO:00069791860.142
catabolic processGO:00090563510.140
organophosphate metabolic processGO:00196373700.139
nucleoside phosphate catabolic processGO:19012921400.138
immune responseGO:00069551040.138
chemical homeostasisGO:00488782920.138
multi organism reproductive processGO:00447032620.137
rna biosynthetic processGO:00327743800.137
positive regulation of multicellular organismal processGO:00512403870.136
positive regulation of transferase activityGO:0051347810.134
ion transmembrane transportGO:00342203650.134
neuron differentiationGO:00301823680.134
positive regulation of cytosolic calcium ion concentrationGO:00072041220.134
regulation of growthGO:00400081050.133
cell activationGO:0001775970.131
vascular process in circulatory systemGO:0003018960.130
negative regulation of cell deathGO:00605482290.130
cellular response to oxygen containing compoundGO:19017013860.130
negative regulation of biosynthetic processGO:00098901680.129
positive regulation of protein transportGO:0051222410.125
regulation of protein secretionGO:0050708280.124
renal system developmentGO:0072001670.124
cellular response to lipopolysaccharideGO:0071222550.122
cellular response to hormone stimulusGO:00328702470.122
cellular response to nitrogen compoundGO:19016992100.121
immune system processGO:00023762040.121
response to lipopolysaccharideGO:00324961910.119
regulation of cytokine productionGO:0001817560.119
negative regulation of apoptotic processGO:00430661810.117
cellular response to organic cyclic compoundGO:00714072020.117
neuron developmentGO:00486662860.117
ion homeostasisGO:00508012120.115
cellular response to organonitrogen compoundGO:00714171970.113
regulation of blood vessel sizeGO:0050880890.113
circulatory system processGO:00030131830.113
carboxylic acid metabolic processGO:00197522890.112
regulation of homeostatic processGO:00328441010.112
peptidyl tyrosine phosphorylationGO:0018108720.112
cellular response to peptideGO:19016531330.111
positive regulation of intracellular signal transductionGO:19025331380.111
regulation of glomerular filtrationGO:000309390.110
tissue regenerationGO:0042246360.109
purine ribonucleotide metabolic processGO:00091502270.107
reproductive structure developmentGO:00486081280.107
regulation of inflammatory responseGO:0050727480.107
cardiovascular system developmentGO:00723581340.106
nitrogen compound transportGO:00717052290.104
purine nucleotide catabolic processGO:00061951360.103
purine nucleotide metabolic processGO:00061632290.100
cellular divalent inorganic cation homeostasisGO:00725031620.099
regulation of blood pressureGO:0008217830.098
regulation of protein localizationGO:0032880810.098
cell growthGO:00160491040.098
response to hydrogen peroxideGO:0042542890.097
cellular response to external stimulusGO:00714961180.096
cell adhesionGO:00071551100.096
divalent inorganic cation homeostasisGO:00725071650.096
response to fluid shear stressGO:0034405160.096
ribonucleotide metabolic processGO:00092592310.096
cell type specific apoptotic processGO:00972851340.095
response to testosteroneGO:0033574550.095
single organism catabolic processGO:00447122830.094
cytokine mediated signaling pathwayGO:0019221430.094
protein heterooligomerizationGO:0051291890.093
positive regulation of interleukin 1 beta secretionGO:005071830.090
response to insulinGO:00328681330.090
regulation of cell growthGO:0001558850.089
regulation of rna biosynthetic processGO:20011413810.089
regulation of mapk cascadeGO:00434081160.088
response to mineralocorticoidGO:0051385490.088
nucleobase containing small molecule metabolic processGO:00550863160.088
renal system processGO:0003014400.088
coagulationGO:0050817280.087
programmed cell deathGO:00125013920.087
cell projection assemblyGO:0030031210.087
nucleoside phosphate metabolic processGO:00067532830.086
kidney morphogenesisGO:0060993130.086
heterotypic cell cell adhesionGO:003411320.085
urogenital system developmentGO:0001655780.084
positive regulation of developmental processGO:00510942830.083
ribonucleoside metabolic processGO:00091191740.083
interleukin 1 beta secretionGO:005070230.083
organelle organizationGO:00069962660.082
oxoacid metabolic processGO:00434362900.082
protein localizationGO:00081041910.081
regulation of ion transportGO:00432692450.081
organic acid metabolic processGO:00060822920.081
circulatory system developmentGO:00723591340.081
glycosyl compound metabolic processGO:19016571820.080
positive regulation of cellular amino acid metabolic processGO:004576410.080
head developmentGO:00603222470.080
biological adhesionGO:00226101100.080
positive regulation of catalytic activityGO:00430851840.080
purine ribonucleoside triphosphate metabolic processGO:00092051400.079
regulation of protein kinase activityGO:00458591050.079
mitotic spindle organizationGO:000705220.079
positive regulation of cell communicationGO:00106472710.078
multicellular organismal reproductive processGO:00486092330.078
multicellular organismal homeostasisGO:0048871490.077
positive regulation of macromolecule biosynthetic processGO:00105572470.077
response to acid chemicalGO:00011012220.077
regulation of protein transportGO:0051223680.076
purine containing compound metabolic processGO:00725212530.076
positive regulation of nucleobase containing compound metabolic processGO:00459353190.076
reproductionGO:00000032450.076
response to reactive oxygen speciesGO:00003021200.075
peptidyl amino acid modificationGO:00181931260.075
response to radiationGO:00093141370.075
regulation of response to external stimulusGO:00321011060.074
positive regulation of nervous system developmentGO:00519621780.074
purine ribonucleoside metabolic processGO:00461281680.074
cellular lipid metabolic processGO:00442552080.073
positive regulation of cellular component organizationGO:00511302000.073
regulation of cellular response to stressGO:0080135490.072
agingGO:00075682410.072
positive regulation of kinase activityGO:0033674770.071
response to extracellular stimulusGO:00099913800.071
erk1 and erk2 cascadeGO:0070371480.071
response to interleukin 1GO:0070555550.071
cellular response to growth factor stimulusGO:00713631620.071
peptidyl tyrosine modificationGO:0018212720.070
regulation of anatomical structure sizeGO:00900661350.070
negative regulation of phosphate metabolic processGO:0045936800.070
response to alkaloidGO:00432791320.070
blood circulationGO:00080151830.070
interleukin 1 secretionGO:005070130.069
regulation of immune responseGO:0050776550.069
muscle contractionGO:0006936880.069
regulation of cell adhesionGO:0030155520.069
regulation of circadian sleep wake cycleGO:0042749180.069
positive regulation of protein serine threonine kinase activityGO:0071902520.069
cell morphogenesis involved in neuron differentiationGO:00486671060.068
cell cycle processGO:0022402570.068
regulation of defense responseGO:0031347680.068
muscle structure developmentGO:0061061870.068
multicellular organism reproductionGO:00325042330.067
regulation of interleukin 1 secretionGO:005070430.067
response to metal ionGO:00100382530.066
negative regulation of cellular metabolic processGO:00313242810.066
organonitrogen compound biosynthetic processGO:19015661670.065
ribonucleoside triphosphate catabolic processGO:00092031220.065
response to dexamethasoneGO:0071548490.065
positive regulation of nucleic acid templated transcriptionGO:19035081970.065
response to purine containing compoundGO:00140741260.065
regulation of metal ion transportGO:00109591180.065
renal filtrationGO:0097205100.064
regulation of system processGO:00440572080.063
negative regulation of nucleobase containing compound metabolic processGO:00459341530.063
cellular response to cytokine stimulusGO:00713451270.063
regulation of vesicle mediated transportGO:0060627810.063
response to mechanical stimulusGO:00096121340.062
negative regulation of cell proliferationGO:00082851190.062
sensory perception of painGO:0019233730.062
positive regulation of cytokine secretionGO:005071590.062
regulation of transferase activityGO:00513381230.061
response to retinoic acidGO:0032526630.061
brain developmentGO:00074202470.061
amine metabolic processGO:0009308380.061
regulation of hydrolase activityGO:00513361430.061
purine ribonucleoside catabolic processGO:00461301240.060
positive regulation of rna biosynthetic processGO:19026801970.060
guanosine containing compound metabolic processGO:1901068740.060
positive regulation of cell differentiationGO:00455972170.060
purine nucleoside metabolic processGO:00422781690.059
positive regulation of immune responseGO:0050778420.059
protein transportGO:00150311320.058
ribose phosphate metabolic processGO:00196932350.058
response to hyperoxiaGO:0055093450.058
response to amino acidGO:0043200750.058
monocarboxylic acid metabolic processGO:00327871520.058
nucleotide catabolic processGO:00091661390.058
regulation of rna metabolic processGO:00512523910.057
regulation of stem cell differentiationGO:200073620.057
regulation of interleukin 1 beta secretionGO:005070630.056
leukocyte homeostasisGO:000177670.056
glomerular filtrationGO:0003094100.056
positive regulation of smooth muscle cell migrationGO:0014911270.056
organ morphogenesisGO:0009887750.056
muscle tissue developmentGO:0060537580.056
regulation of programmed cell deathGO:00430673410.056
purine containing compound catabolic processGO:00725231380.056
apoptotic processGO:00069153810.056
blood vessel morphogenesisGO:0048514580.055
regulation of leukocyte migrationGO:0002685240.055
regulation of cellular amino acid metabolic processGO:000652120.055
sexual reproductionGO:00199531480.055
regulation of muscle system processGO:0090257790.055
developmental growthGO:00485891000.055
action potentialGO:0001508540.055
cellular response to peptide hormone stimulusGO:00713751200.054
regulation of catabolic processGO:00098941130.054
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.054
negative regulation of macromolecule biosynthetic processGO:00105581480.054
cellular catabolic processGO:00442482950.054
neuronal action potentialGO:0019228350.054
blood vessel developmentGO:0001568690.054
cardiac chamber developmentGO:000320510.054
nucleoside triphosphate metabolic processGO:00091411440.053
cellular response to insulin stimulusGO:0032869810.053
negative regulation of transportGO:00510511360.053
embryonic skeletal system developmentGO:004870630.052
regulation of map kinase activityGO:0043405530.052
neurological system processGO:00508772190.052
response to transforming growth factor betaGO:0071559460.052
response to decreased oxygen levelsGO:00362932370.052
regulation of circadian sleep wake cycle sleepGO:0045187180.052
cellular amine metabolic processGO:0044106380.052
response to gamma radiationGO:0010332240.052
nucleotide metabolic processGO:00091172790.052
regulation of cellular catabolic processGO:00313291010.052
positive regulation of behaviorGO:0048520380.052
cell part morphogenesisGO:00329901230.051
lipid biosynthetic processGO:00086101280.051
regulation of neuron deathGO:19012141150.051
carbohydrate derivative catabolic processGO:19011361470.051
response to increased oxygen levelsGO:0036296450.051
phospholipid metabolic processGO:0006644610.051
central nervous system developmentGO:00074173110.051
embryonic appendage morphogenesisGO:003511340.051
positive regulation of hydrolase activityGO:0051345860.051
nucleoside triphosphate catabolic processGO:00091431230.050
negative regulation of cellular biosynthetic processGO:00313271610.050
rhythmic processGO:00485111560.050
protein kinase c activating g protein coupled receptor signaling pathwayGO:0007205120.049
hormone transportGO:00099141210.049
regulation of membrane potentialGO:00423911100.049
axon developmentGO:0061564960.049
single organism cell adhesionGO:0098602460.048
regulation of hormone levelsGO:00108171870.048
cytoskeleton organizationGO:00070101110.048
development of primary sexual characteristicsGO:00451371070.048
vasculature developmentGO:0001944700.048
establishment of protein localizationGO:00451841410.048
ribonucleoside catabolic processGO:00424541260.047
regulation of lipid metabolic processGO:0019216680.047
regulation of nucleotide metabolic processGO:00061401170.047
regulation of cellular ketone metabolic processGO:0010565270.047
limb morphogenesisGO:003510840.047
negative regulation of signal transductionGO:0009968830.047
small gtpase mediated signal transductionGO:0007264360.046
membrane organizationGO:0061024940.046
glycosyl compound catabolic processGO:19016581260.046
calcium ion transportGO:00068161310.045
positive regulation of molecular functionGO:00440932300.045
anion transportGO:00068201780.045
positive regulation of cellular amine metabolic processGO:003324030.045
transmembrane transportGO:00550854120.045
cation transmembrane transportGO:00986552630.045
cellular response to lipidGO:00713962010.045
response to tumor necrosis factorGO:0034612560.045
response to campGO:0051591910.045
cellular response to fluid shear stressGO:007149840.044
cytokine secretionGO:0050663150.044
negative regulation of programmed cell deathGO:00430691830.044
neuron deathGO:00709971270.044
tube morphogenesisGO:0035239230.044
regulation of endocytosisGO:0030100420.044
cell cell junction organizationGO:0045216200.044
embryonic cranial skeleton morphogenesisGO:004870120.044
regulation of cell activationGO:0050865500.043
negative regulation of gene expressionGO:00106291990.043
hormone secretionGO:00468791150.043
hepatocyte differentiationGO:007036580.043
regulation of dna metabolic processGO:0051052600.043
neural crest cell differentiationGO:001403320.043
regulation of establishment of protein localizationGO:0070201690.043
regulation of fc receptor mediated stimulatory signaling pathwayGO:006036830.042
purine nucleoside triphosphate metabolic processGO:00091441410.042
eye morphogenesisGO:004859240.042
nucleobase containing compound catabolic processGO:00346551520.042
cellular response to interleukin 1GO:0071347370.042
single organism cellular localizationGO:19025801020.042
potassium ion transportGO:0006813970.042
response to nutrient levelsGO:00316673700.041
positive regulation of inflammatory responseGO:0050729240.041
ribonucleotide catabolic processGO:00092611360.041
negative regulation of neuron apoptotic processGO:0043524450.041
purine nucleoside triphosphate catabolic processGO:00091461220.041
cellular response to transforming growth factor beta stimulusGO:0071560410.041
response to temperature stimulusGO:0009266940.041
myeloid leukocyte activationGO:0002274360.041
positive regulation of mesenchymal cell proliferationGO:000205340.041
cellular ketone metabolic processGO:0042180510.041
positive regulation of leukocyte migrationGO:0002687210.040
transforming growth factor beta receptor signaling pathwayGO:0007179180.040
regulation of cellular amine metabolic processGO:003323880.040
regulation of cellular component biogenesisGO:0044087860.040
embryonic pattern specificationGO:000988010.040
intracellular transportGO:00469071850.039
gastrulationGO:000736920.039
regulation of cell differentiationGO:00455953200.039
smooth muscle cell proliferationGO:0048659770.039
single organism organelle organizationGO:19025891800.039
response to glucoseGO:00097491360.039
positive regulation of mapk cascadeGO:0043410920.039
regulation of protein serine threonine kinase activityGO:0071900640.039
response to toxic substanceGO:00096361330.038
sex differentiationGO:00075481130.038
positive regulation of cell projection organizationGO:00313461110.038
aromatic compound catabolic processGO:00194391680.037
regulation of blood circulationGO:19035221100.037
regulation of canonical wnt signaling pathwayGO:006082840.037
protein targetingGO:0006605610.036
anterior posterior pattern specificationGO:000995210.036
purine nucleoside catabolic processGO:00061521240.036
cellular response to mechanical stimulusGO:0071260480.036
skeletal system developmentGO:0001501410.036
female gonad developmentGO:0008585530.036
organic anion transportGO:00157111320.036
cellular amino acid metabolic processGO:00065201070.036
positive regulation of map kinase activityGO:0043406460.036
response to transition metal nanoparticleGO:19902671220.035
ensheathment of neuronsGO:0007272400.035
organophosphate biosynthetic processGO:00904071430.035
negative regulation of phosphorus metabolic processGO:0010563800.035
regulation of tight junction assemblyGO:200081020.035
dna metabolic processGO:0006259960.035
cognitionGO:0050890920.035
gonad developmentGO:00084061040.035
endocytosisGO:0006897840.034
regulation of kinase activityGO:00435491170.034
muscle cell proliferationGO:0033002840.034
single organism intracellular transportGO:19025821660.034
positive regulation of response to external stimulusGO:0032103510.034
developmental process involved in reproductionGO:00030061590.034
cellular protein localizationGO:00346131220.034
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.033
renal sodium excretionGO:0035812200.033
response to vitamin dGO:0033280340.033
embryonic skeletal system morphogenesisGO:004870430.033
regulation of behaviorGO:0050795610.033
organic acid transportGO:00158491160.033
regulation of heterotypic cell cell adhesionGO:003411420.032
synaptic transmissionGO:00072682350.032
regulation of epithelial cell proliferationGO:0050678490.032
circadian rhythmGO:0007623880.032
leukocyte activationGO:0045321760.032
positive regulation of cellular component biogenesisGO:0044089550.032
positive regulation of cell adhesionGO:0045785300.032
positive regulation of protein kinase activityGO:0045860730.032
female sex differentiationGO:0046660590.032

S1pr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system cancerDOID:311900.105
organ system cancerDOID:005068600.105
disease of cellular proliferationDOID:1456600.105
cancerDOID:16200.105
disease of anatomical entityDOID:700.068
nervous system diseaseDOID:86300.068
musculoskeletal system diseaseDOID:1700.032