Rattus norvegicus

0 known processes

Mapk6

mitogen-activated protein kinase 6

(Aliases: ERK3,MGC124957)

Mapk6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203650.252
rna biosynthetic processGO:00327743800.231
inorganic ion transmembrane transportGO:00986602290.193
positive regulation of cellular component movementGO:00512721020.188
metal ion transportGO:00300012890.175
cellular response to stressGO:00335542690.174
positive regulation of gene expressionGO:00106282440.162
nucleic acid templated transcriptionGO:00976593790.156
regulation of transcription dna templatedGO:00063553740.153
cation transmembrane transportGO:00986552630.153
positive regulation of cell deathGO:00109421840.150
cation transportGO:00068123820.150
agingGO:00075682410.145
regulation of cell differentiationGO:00455953200.145
transcription dna templatedGO:00063513770.144
regulation of nucleic acid templated transcriptionGO:19035063800.137
oxoacid metabolic processGO:00434362900.134
regulation of catalytic activityGO:00507903040.132
response to biotic stimulusGO:00096072260.127
positive regulation of cell migrationGO:0030335960.125
transcription from rna polymerase ii promoterGO:00063662520.120
blood vessel developmentGO:0001568690.117
regulation of cell proliferationGO:00421273590.116
intracellular signal transductionGO:00355563140.115
Mouse
positive regulation of transcription dna templatedGO:00458931970.114
apoptotic processGO:00069153810.112
response to hypoxiaGO:00016662310.112
regulation of phosphorus metabolic processGO:00511743490.110
response to nutrientGO:00075842480.110
positive regulation of developmental processGO:00510942830.106
transmembrane transportGO:00550854120.105
positive regulation of cell differentiationGO:00455972170.105
ras protein signal transductionGO:0007265290.105
carboxylic acid metabolic processGO:00197522890.103
regulation of rna metabolic processGO:00512523910.101
response to radiationGO:00093141370.100
response to metal ionGO:00100382530.100
response to inorganic substanceGO:00100353770.099
regulation of stress activated protein kinase signaling cascadeGO:0070302230.099
inorganic cation transmembrane transportGO:00986622020.098
regulation of rna biosynthetic processGO:20011413810.096
mesoderm developmentGO:000749820.095
response to nutrient levelsGO:00316673700.094
carbohydrate derivative metabolic processGO:19011353460.094
protein oligomerizationGO:00512591910.093
nitrogen compound transportGO:00717052290.093
inflammatory responseGO:00069541500.092
response to oxygen levelsGO:00704822650.090
tissue developmentGO:00098882520.088
protein heterooligomerizationGO:0051291890.088
mapk cascadeGO:00001651400.085
Mouse
sodium ion transportGO:0006814820.084
regulation of mapk cascadeGO:00434081160.082
positive regulation of response to stimulusGO:00485842850.079
regulation of cellular response to stressGO:0080135490.079
positive regulation of cell motilityGO:2000147970.078
cellular response to endogenous stimulusGO:00714953770.078
regulation of intracellular signal transductionGO:19025312180.077
regulation of molecular functionGO:00650093980.076
enzyme linked receptor protein signaling pathwayGO:00071671160.075
peptide transportGO:0015833970.075
organonitrogen compound biosynthetic processGO:19015661670.074
anion transmembrane transportGO:0098656770.074
defense responseGO:00069521940.073
signal transduction by phosphorylationGO:00230141440.073
Mouse
positive regulation of biosynthetic processGO:00098913190.070
cellular response to abiotic stimulusGO:0071214850.070
organic acid metabolic processGO:00060822920.069
macromolecule localizationGO:00330362520.069
cellular response to hormone stimulusGO:00328702470.064
reproductive processGO:00224143720.063
response to corticosteroidGO:00319602350.063
cell migrationGO:00164771970.062
response to decreased oxygen levelsGO:00362932370.062
cellular response to peptideGO:19016531330.061
growthGO:00400071650.061
cell motilityGO:00488702020.060
response to transition metal nanoparticleGO:19902671220.060
protein complex biogenesisGO:00702712630.060
positive regulation of rna biosynthetic processGO:19026801970.060
rhythmic processGO:00485111560.059
cellular amine metabolic processGO:0044106380.059
positive regulation of signalingGO:00230562700.058
cellular response to alcoholGO:0097306870.058
regulation of programmed cell deathGO:00430673410.058
regulation of cell motilityGO:20001451310.058
macromolecular complex assemblyGO:00650032730.057
negative regulation of metabolic processGO:00098923310.057
response to glucocorticoidGO:00513842230.057
cellular amino acid metabolic processGO:00065201070.056
programmed cell deathGO:00125013920.056
response to monosaccharideGO:00342841590.054
response to estrogenGO:00436272320.054
gastrulationGO:000736920.053
catabolic processGO:00090563510.053
neuron differentiationGO:00301823680.053
regulation of multicellular organismal developmentGO:20000263760.052
neuron projection developmentGO:00311752730.052
response to carbohydrateGO:00097431830.052
positive regulation of programmed cell deathGO:00430681570.051
sodium ion transmembrane transportGO:0035725670.051
monovalent inorganic cation transportGO:00156721720.051
response to ethanolGO:00454711620.051
regulation of phosphorylationGO:00423252480.051
neuron apoptotic processGO:0051402880.051
protein complex subunit organizationGO:00718223020.051
positive regulation of cell communicationGO:00106472710.050
positive regulation of mapk cascadeGO:0043410920.050
single organism reproductive processGO:00447022970.049
positive regulation of macromolecule biosynthetic processGO:00105572470.048
positive regulation of cellular biosynthetic processGO:00313282950.048
intracellular transportGO:00469071850.048
positive regulation of nucleic acid templated transcriptionGO:19035081970.048
response to peptideGO:19016522920.048
regulation of protein metabolic processGO:00512462890.047
sulfur compound metabolic processGO:0006790700.047
cellular response to oxygen containing compoundGO:19017013860.047
cellular response to organic cyclic compoundGO:00714072020.047
regulation of transcription from rna polymerase ii promoterGO:00063572340.047
dephosphorylationGO:0016311980.046
response to external biotic stimulusGO:00432072210.046
positive regulation of locomotionGO:00400171020.045
regulation of phosphate metabolic processGO:00192203490.045
positive regulation of apoptotic processGO:00430651540.045
proteolysisGO:00065081750.045
regulation of cellular ketone metabolic processGO:0010565270.044
protein targeting to nucleusGO:0044744350.043
cellular response to nitrogen compoundGO:19016992100.043
response to woundingGO:00096112540.043
cell cycle checkpointGO:000007520.043
positive regulation of cell developmentGO:00107201760.043
regulation of peptide transportGO:0090087870.043
positive regulation of protein metabolic processGO:00512471780.043
gland developmentGO:00487321550.043
macromolecular complex subunit organizationGO:00439333390.042
locomotionGO:00400112370.042
amide transportGO:00428861050.042
cellular chemical homeostasisGO:00550822470.042
cell cell signalingGO:00072673350.042
nucleobase containing small molecule metabolic processGO:00550863160.041
regulation of apoptotic processGO:00429813350.041
protein dephosphorylationGO:0006470380.040
cell growthGO:00160491040.039
cellular response to insulin stimulusGO:0032869810.039
positive regulation of rna metabolic processGO:00512542030.039
regulation of map kinase activityGO:0043405530.039
response to extracellular stimulusGO:00099913800.039
regulation of stress activated mapk cascadeGO:0032872230.039
epithelium developmentGO:0060429960.039
vasculature developmentGO:0001944700.039
cell projection organizationGO:00300303020.039
multi organism reproductive processGO:00447032620.038
regulation of signal transductionGO:00099663180.038
positive regulation of phosphorus metabolic processGO:00105622620.038
positive regulation of signal transductionGO:00099671750.038
neuron deathGO:00709971270.038
organonitrogen compound catabolic processGO:19015651790.038
nucleotide metabolic processGO:00091172790.037
cellular ketone metabolic processGO:0042180510.037
regulation of locomotionGO:00400121480.037
organic substance catabolic processGO:19015753160.037
amine metabolic processGO:0009308380.036
circulatory system processGO:00030131830.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
negative regulation of programmed cell deathGO:00430691830.036
synaptic transmissionGO:00072682350.036
sexual reproductionGO:00199531480.035
cellular catabolic processGO:00442482950.035
organophosphate metabolic processGO:00196373700.035
protein complex assemblyGO:00064612630.035
alpha amino acid metabolic processGO:1901605710.035
cellular response to cytokine stimulusGO:00713451270.034
response to estradiolGO:00323551640.034
response to manganese ionGO:0010042130.034
protein localization to organelleGO:0033365570.034
regulation of transcription elongation from rna polymerase ii promoterGO:003424340.034
regulation of cellular amine metabolic processGO:003323880.034
nucleocytoplasmic transportGO:0006913480.034
multicellular organism reproductionGO:00325042330.033
response to acid chemicalGO:00011012220.033
nuclear importGO:0051170350.033
ribonucleotide metabolic processGO:00092592310.033
multicellular organism growthGO:003526410.033
organic hydroxy compound metabolic processGO:19016151150.033
cellular response to peptide hormone stimulusGO:00713751200.032
positive regulation of intracellular signal transductionGO:19025331380.032
neuron developmentGO:00486662860.032
ribose phosphate metabolic processGO:00196932350.032
positive regulation of transportGO:00510502450.032
embryonic pattern specificationGO:000988010.032
regulation of cellular amino acid metabolic processGO:000652120.032
negative regulation of apoptotic processGO:00430661810.031
response to hexoseGO:00097461440.031
negative regulation of cell deathGO:00605482290.031
cell type specific apoptotic processGO:00972851340.031
stress activated protein kinase signaling cascadeGO:0031098370.031
regulation of cell cycleGO:0051726730.031
guanosine containing compound metabolic processGO:1901068740.031
regulation of tube sizeGO:0035150890.031
chromosome segregationGO:000705920.031
g protein coupled receptor signaling pathwayGO:00071862420.031
regulation of ion transportGO:00432692450.031
small gtpase mediated signal transductionGO:0007264360.030
response to alkaloidGO:00432791320.030
coenzyme metabolic processGO:0006732860.030
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.030
cellular component morphogenesisGO:00329891550.030
negative regulation of cell communicationGO:00106481580.030
purine containing compound catabolic processGO:00725231380.030
response to lipopolysaccharideGO:00324961910.030
regulation of homotypic cell cell adhesionGO:003411040.030
divalent metal ion transportGO:00708381320.030
response to ketoneGO:19016541820.030
cellular component movementGO:00069282480.029
hormone transportGO:00099141210.029
cellular modified amino acid biosynthetic processGO:0042398180.029
tissue morphogenesisGO:0048729220.029
regulation of cellular localizationGO:00603412630.029
ion homeostasisGO:00508012120.029
positive regulation of cell proliferationGO:00082842490.029
response to toxic substanceGO:00096361330.029
regulation of transferase activityGO:00513381230.029
purine ribonucleotide catabolic processGO:00091541360.029
positive regulation of protein serine threonine kinase activityGO:0071902520.029
cellular response to organonitrogen compoundGO:00714171970.028
negative regulation of macromolecule metabolic processGO:00106052600.028
chemical homeostasisGO:00488782920.028
negative regulation of biosynthetic processGO:00098901680.028
cofactor biosynthetic processGO:0051188280.028
response to peptide hormoneGO:00434342780.028
establishment of protein localizationGO:00451841410.028
reactive oxygen species metabolic processGO:0072593370.028
negative regulation of cell cycle phase transitionGO:190198840.028
purine nucleoside metabolic processGO:00422781690.028
reproductionGO:00000032450.028
divalent inorganic cation transportGO:00725111340.028
regulation of protein import into nucleusGO:0042306240.027
protein importGO:0017038370.027
response to vitaminGO:00332731310.027
regulation of cellular component movementGO:00512701500.027
anatomical structure morphogenesisGO:00096532980.027
regulation of protein phosphorylationGO:00019321830.027
positive regulation of nitrogen compound metabolic processGO:00511733340.027
circulatory system developmentGO:00723591340.027
blood circulationGO:00080151830.027
developmental process involved in reproductionGO:00030061590.027
purine ribonucleoside metabolic processGO:00461281680.027
positive regulation of map kinase activityGO:0043406460.027
negative regulation of cellular metabolic processGO:00313242810.026
multicellular organismal reproductive processGO:00486092330.026
cellular protein localizationGO:00346131220.026
nucleoside catabolic processGO:00091641260.026
regulation of response to external stimulusGO:00321011060.026
cardiac ventricle developmentGO:000323110.026
negative regulation of cellular biosynthetic processGO:00313271610.026
rna metabolic processGO:00160704060.026
negative regulation of transportGO:00510511360.026
positive regulation of protein phosphorylationGO:00019341350.025
regulation of hormone secretionGO:00468831060.025
regulation of response to woundingGO:1903034690.025
asymmetric stem cell divisionGO:009872220.025
regulation of anatomical structure sizeGO:00900661350.025
ribonucleoside metabolic processGO:00091191740.025
regulation of response to stressGO:00801341260.025
cellular homeostasisGO:00197252520.025
regulation of blood circulationGO:19035221100.025
response to growth factorGO:00708481890.025
positive regulation of cell projection organizationGO:00313461110.025
regulation of insulin secretionGO:0050796650.025
anion transportGO:00068201780.024
positive regulation of protein kinase activityGO:0045860730.024
single organism biosynthetic processGO:00447113420.024
mitotic cell cycleGO:0000278490.024
regulation of neuron projection developmentGO:00109751610.024
reproductive structure developmentGO:00486081280.024
cofactor metabolic processGO:0051186950.024
negative regulation of macromolecule biosynthetic processGO:00105581480.024
purine containing compound metabolic processGO:00725212530.024
axis specificationGO:000979840.024
cellular response to external stimulusGO:00714961180.023
urogenital system developmentGO:0001655780.023
axon developmentGO:0061564960.023
brain developmentGO:00074202470.023
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296830.023
digestive tract developmentGO:0048565390.023
anterior posterior pattern specificationGO:000995210.023
protein catabolic processGO:0030163300.023
vascular process in circulatory systemGO:0003018960.023
homeostatic processGO:00425923310.023
embryonic axis specificationGO:000057810.023
ribonucleotide catabolic processGO:00092611360.023
negative regulation of transcription dna templatedGO:00458921160.023
cardiovascular system developmentGO:00723581340.023
organelle inheritanceGO:004830820.023
positive regulation of phosphorylationGO:00423271770.023
nucleoside triphosphate metabolic processGO:00091411440.023
regulation of proteolysisGO:0030162660.023
negative regulation of signalingGO:00230571570.022
carbohydrate derivative catabolic processGO:19011361470.022
neuron projection morphogenesisGO:00488121220.022
cellular metal ion homeostasisGO:00068751720.022
negative regulation of molecular functionGO:00440921330.022
nucleobase containing compound catabolic processGO:00346551520.022
response to light stimulusGO:0009416520.022
single organism catabolic processGO:00447122830.022
negative regulation of multicellular organismal processGO:00512412030.022
positive regulation of nervous system developmentGO:00519621780.022
wound healingGO:00420601220.022
cellular nitrogen compound catabolic processGO:00442701630.022
monocarboxylic acid metabolic processGO:00327871520.021
positive regulation of protein modification processGO:00314011420.021
positive regulation of cellular protein metabolic processGO:00322701670.021
regulation of neuron deathGO:19012141150.021
regulation of nucleocytoplasmic transportGO:0046822280.021
response to other organismGO:00517072200.021
somatic stem cell divisionGO:004810320.021
positive regulation of neuron deathGO:1901216430.021
dna metabolic processGO:0006259960.021
positive regulation of cellular amine metabolic processGO:003324030.021
p38mapk cascadeGO:003806610.021
blood vessel morphogenesisGO:0048514580.021
response to glucoseGO:00097491360.021
cellular response to lipidGO:00713962010.021
negative regulation of signal transductionGO:0009968830.021
negative regulation of mitotic cell cycle phase transitionGO:190199130.021
reactive oxygen species biosynthetic processGO:190340980.021
regulation of peptide secretionGO:0002791820.021
regulation of neurogenesisGO:00507672470.020
purine ribonucleoside catabolic processGO:00461301240.020
single organism nuclear importGO:1902593350.020
positive regulation of molecular functionGO:00440932300.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
cellular macromolecule localizationGO:00707271220.020
glycosyl compound metabolic processGO:19016571820.020
cellular cation homeostasisGO:00300031800.020
nucleoside phosphate metabolic processGO:00067532830.020
regulation of nucleotide metabolic processGO:00061401170.020
cellular component biogenesisGO:00440853680.020
response to osmotic stressGO:0006970420.020
central nervous system developmentGO:00074173110.020
regulation of blood vessel sizeGO:0050880890.020
regulation of metal ion transportGO:00109591180.020
organic cyclic compound catabolic processGO:19013611750.020
neuron neuron synaptic transmissionGO:0007270600.019
neural precursor cell proliferationGO:0061351230.019
melanosome localizationGO:003240010.019
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
cellular amino acid biosynthetic processGO:0008652320.019
protein transportGO:00150311320.019
muscle cell proliferationGO:0033002840.019
regulation of secretionGO:00510462240.019
regulation of nitric oxide synthase activityGO:005099980.019
regulation of peptide hormone secretionGO:0090276800.019
regulation of neuron apoptotic processGO:0043523830.019
cellular response to growth factor stimulusGO:00713631620.019
bmp signaling pathwayGO:003050940.019
calcium ion transportGO:00068161310.019
response to insulinGO:00328681330.019
stress activated mapk cascadeGO:0051403350.019
regulation of cell developmentGO:00602842630.019
regulation of reactive oxygen species metabolic processGO:2000377260.019
mast cell migrationGO:009753140.019
response to ammonium ionGO:0060359710.019
regulation of protein localizationGO:0032880810.019
regulation of synaptic transmissionGO:00508041410.018
regulation of protein targetingGO:1903533280.018
response to transforming growth factor betaGO:0071559460.018
regulation of secretion by cellGO:19035302080.018
activation of cysteine type endopeptidase activityGO:009720240.018
response to cytokineGO:00340972150.018
cation homeostasisGO:00550801950.018
mesoderm formationGO:000170710.018
secretionGO:00469033070.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
tube morphogenesisGO:0035239230.018
positive regulation of neuron differentiationGO:00456661260.018
chlorinated hydrocarbon metabolic processGO:004219640.018
sex differentiationGO:00075481130.018
head developmentGO:00603222470.018
positive regulation of phosphate metabolic processGO:00459372620.018
protein phosphorylationGO:00064683450.017
Mouse
regulation of hydrolase activityGO:00513361430.017
regulation of ion transmembrane transportGO:00347651210.017
neurological system processGO:00508772190.017
signal releaseGO:00230611450.017
cell projection morphogenesisGO:00488581230.017
positive regulation of kinase activityGO:0033674770.017
organic anion transportGO:00157111320.017
gonad developmentGO:00084061040.017
smad protein complex assemblyGO:000718310.017
regulation of cytokine productionGO:0001817560.017
cell cycleGO:00070491010.017
ribonucleoside catabolic processGO:00424541260.017
single organism cellular localizationGO:19025801020.017
regulation of oxidoreductase activityGO:0051341110.017
protein localizationGO:00081041910.017
regulation of protein kinase activityGO:00458591050.017
establishment of protein localization to organelleGO:0072594440.017
response to oxidative stressGO:00069791860.017
cellular modified amino acid metabolic processGO:0006575610.017
positive regulation of multicellular organismal processGO:00512403870.017
regulation of transmembrane transportGO:00347621220.017
positive regulation of catalytic activityGO:00430851840.017
glucose homeostasisGO:0042593750.017
purine nucleoside catabolic processGO:00061521240.017
macromolecule catabolic processGO:0009057580.017
regulation of purine nucleotide metabolic processGO:19005421150.017
regulation of vascular smooth muscle contractionGO:000305630.017
positive regulation of transferase activityGO:0051347810.017
cyclic nucleotide metabolic processGO:0009187800.017
response to organophosphorusGO:00466831020.016
cell fate determinationGO:000170920.016
metal ion homeostasisGO:00550651860.016
regulation of cell projection organizationGO:00313441750.016
response to axon injuryGO:0048678590.016
protein autophosphorylationGO:0046777660.016
positive regulation of erk1 and erk2 cascadeGO:0070374290.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
heterocycle catabolic processGO:00467001670.016
response to temperature stimulusGO:0009266940.016
angiogenesisGO:0001525530.016
positive regulation of cellular component organizationGO:00511302000.016
carboxylic acid transportGO:00469421150.016
nucleoside metabolic processGO:00091161790.016
regulation of kinase activityGO:00435491170.016
cellular response to metal ionGO:0071248550.016
gtp catabolic processGO:0006184710.015
nuclear transportGO:0051169490.015
regulation of cell migrationGO:00303341280.015
protein import into nucleusGO:0006606350.015
biological adhesionGO:00226101100.015
positive regulation of cellular catabolic processGO:0031331710.015
regulation of hormone levelsGO:00108171870.015
response to molecule of bacterial originGO:00022371940.015
cytoplasmic transportGO:00164821150.015
cell morphogenesisGO:00009021420.015
epithelial cell differentiationGO:0030855710.015
purine nucleotide catabolic processGO:00061951360.015
microtubule based processGO:0007017360.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
sulfur compound biosynthetic processGO:0044272190.015
positive regulation of neuron projection developmentGO:0010976990.015
protein modification by small protein conjugation or removalGO:0070647350.015
lipid metabolic processGO:00066292830.015
small molecule biosynthetic processGO:00442831240.015
erk1 and erk2 cascadeGO:0070371480.015
divalent inorganic cation homeostasisGO:00725071650.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
nucleoside phosphate catabolic processGO:19012921400.015
eye developmentGO:0001654500.015
positive regulation of neurogenesisGO:00507691650.015
regulation of protein modification processGO:00313991940.015
mitotic cell cycle processGO:1903047350.015
immune system processGO:00023762040.014
vesicle mediated transportGO:00161921810.014
organic acid biosynthetic processGO:0016053830.014
negative regulation of ion transportGO:0043271510.014
positive regulation of catabolic processGO:0009896780.014
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.014
dna integrity checkpointGO:003157020.014
muscle system processGO:00030121150.014
negative regulation of catalytic activityGO:00430861030.014
negative regulation of cell proliferationGO:00082851190.014
adult locomotory behaviorGO:000834440.014
protein sumoylationGO:001692540.014
regulation of p38mapk cascadeGO:190074410.014
guanosine containing compound catabolic processGO:1901069710.014
response to retinoic acidGO:0032526630.014
neuronal stem cell divisionGO:003644510.014
embryonic placenta developmentGO:000189210.014
single organism intracellular transportGO:19025821660.014
cellular response to inorganic substanceGO:0071241650.014
regulation of anion transportGO:0044070430.014
negative regulation of response to stimulusGO:00485851550.014
golgi organizationGO:0007030170.014
neural crest cell developmentGO:001403220.014
cytoskeleton organizationGO:00070101110.013
keratinocyte differentiationGO:003021620.013
purine ribonucleotide metabolic processGO:00091502270.013
autophagyGO:0006914190.013
muscle contractionGO:0006936880.013
cell part morphogenesisGO:00329901230.013
gtp metabolic processGO:0046039720.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
carbohydrate homeostasisGO:0033500750.013
spermatogenesisGO:0007283990.013
positive regulation of hydrolase activityGO:0051345860.013

Mapk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
musculoskeletal system diseaseDOID:1700.017
organ system cancerDOID:005068600.015