| cellular macromolecule catabolic process | GO:0044265 | 29 | 0.273 | |
| protein refolding | GO:0042026 | 3 | 0.253 | Human |
| rna metabolic process | GO:0016070 | 406 | 0.233 | |
| macromolecule catabolic process | GO:0009057 | 58 | 0.213 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.213 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.201 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.199 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.170 | |
| cellular component assembly | GO:0022607 | 360 | 0.169 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.163 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 14 | 0.147 | |
| modification dependent protein catabolic process | GO:0019941 | 14 | 0.131 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.123 | |
| protein localization | GO:0008104 | 191 | 0.120 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.111 | |
| protein ubiquitination | GO:0016567 | 28 | 0.106 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.098 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.096 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.092 | |
| protein transport | GO:0015031 | 132 | 0.083 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.082 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.081 | |
| regulation of protein transport | GO:0051223 | 68 | 0.080 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.080 | |
| programmed cell death | GO:0012501 | 392 | 0.074 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 1 | 0.072 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.072 | |
| transcription dna templated | GO:0006351 | 377 | 0.071 | |
| protein catabolic process | GO:0030163 | 30 | 0.070 | |
| intracellular transport | GO:0046907 | 185 | 0.069 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 19 | 0.069 | |
| organelle organization | GO:0006996 | 266 | 0.068 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.068 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.067 | |
| positive regulation of transport | GO:0051050 | 245 | 0.066 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.064 | |
| macromolecule localization | GO:0033036 | 252 | 0.063 | |
| cardiovascular system development | GO:0072358 | 134 | 0.062 | |
| myosin filament assembly | GO:0031034 | 1 | 0.058 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.058 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 7 | 0.057 | |
| catabolic process | GO:0009056 | 351 | 0.056 | |
| nucleocytoplasmic transport | GO:0006913 | 48 | 0.055 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.052 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.051 | |
| cellular macromolecular complex assembly | GO:0034622 | 58 | 0.050 | |
| cellular response to stress | GO:0033554 | 269 | 0.050 | |
| cellular protein complex assembly | GO:0043623 | 44 | 0.050 | |
| single organism organelle organization | GO:1902589 | 180 | 0.048 | |
| positive regulation of protein transport | GO:0051222 | 41 | 0.047 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.045 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.045 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.044 | |
| protein complex assembly | GO:0006461 | 263 | 0.043 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 4 | 0.043 | |
| cellular response to organic cyclic compound | GO:0071407 | 202 | 0.042 | |
| regulation of protein import into nucleus | GO:0042306 | 24 | 0.040 | |
| reproductive process | GO:0022414 | 372 | 0.038 | |
| microtubule organizing center organization | GO:0031023 | 1 | 0.038 | |
| proteolysis | GO:0006508 | 175 | 0.038 | |
| dna metabolic process | GO:0006259 | 96 | 0.037 | Human |
| apoptotic process | GO:0006915 | 381 | 0.036 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.035 | |
| regulation of establishment of protein localization | GO:0070201 | 69 | 0.035 | |
| single organism reproductive process | GO:0044702 | 297 | 0.035 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.034 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.034 | |
| cellular protein catabolic process | GO:0044257 | 19 | 0.033 | |
| reproduction | GO:0000003 | 245 | 0.033 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.033 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.032 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.032 | |
| homeostatic process | GO:0042592 | 331 | 0.032 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.032 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.031 | |
| cellular catabolic process | GO:0044248 | 295 | 0.031 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.030 | |
| response to growth factor | GO:0070848 | 189 | 0.029 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 28 | 0.028 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.028 | |
| establishment of protein localization | GO:0045184 | 141 | 0.027 | |
| response to heat | GO:0009408 | 60 | 0.027 | |
| spindle organization | GO:0007051 | 2 | 0.027 | |
| regulation of protein targeting | GO:1903533 | 28 | 0.026 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.026 | |
| regulation of protein localization | GO:0032880 | 81 | 0.026 | |
| regulation of response to stress | GO:0080134 | 126 | 0.026 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.025 | |
| dna replication | GO:0006260 | 37 | 0.025 | Human |
| circulatory system process | GO:0003013 | 183 | 0.025 | |
| actin filament based process | GO:0030029 | 86 | 0.025 | |
| organelle assembly | GO:0070925 | 22 | 0.025 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.024 | |
| single organism cellular localization | GO:1902580 | 102 | 0.024 | |
| mitotic spindle organization | GO:0007052 | 2 | 0.024 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 14 | 0.024 | |
| regulation of striated muscle contraction | GO:0006942 | 21 | 0.023 | |
| muscle system process | GO:0003012 | 115 | 0.023 | |
| actin cytoskeleton organization | GO:0030036 | 73 | 0.023 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.023 | |
| cellular protein localization | GO:0034613 | 122 | 0.023 | |
| regulation of secretion | GO:0051046 | 224 | 0.022 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.022 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.022 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.022 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.022 | |
| positive regulation of dna metabolic process | GO:0051054 | 39 | 0.022 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.022 | |
| trna metabolic process | GO:0006399 | 4 | 0.022 | |
| sexual reproduction | GO:0019953 | 148 | 0.022 | |
| ncrna processing | GO:0034470 | 3 | 0.022 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.021 | |
| regulation of intracellular transport | GO:0032386 | 65 | 0.021 | |
| cellular response to dna damage stimulus | GO:0006974 | 19 | 0.020 | |
| regulation of protein catabolic process | GO:0042176 | 16 | 0.020 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.020 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.020 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 80 | 0.020 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 141 | 0.019 | |
| somatic diversification of immunoglobulins involved in immune response | GO:0002208 | 1 | 0.019 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.018 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 3 | 0.018 | |
| regulation of dna metabolic process | GO:0051052 | 60 | 0.018 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 45 | 0.017 | |
| centrosome organization | GO:0051297 | 1 | 0.017 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.017 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.017 | |
| response to oxidative stress | GO:0006979 | 186 | 0.017 | |
| proteasomal protein catabolic process | GO:0010498 | 8 | 0.017 | |
| nuclear transport | GO:0051169 | 49 | 0.017 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.017 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.016 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.016 | |
| endocytosis | GO:0006897 | 84 | 0.016 | |
| neuron death | GO:0070997 | 127 | 0.016 | |
| regulation of cell projection organization | GO:0031344 | 175 | 0.016 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.016 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.016 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 17 | 0.016 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.016 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.016 | |
| negative regulation of neuron death | GO:1901215 | 69 | 0.015 | |
| response to inorganic substance | GO:0010035 | 377 | 0.015 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.015 | |
| regulation of neuron apoptotic process | GO:0043523 | 83 | 0.015 | |
| immunoglobulin mediated immune response | GO:0016064 | 4 | 0.015 | |
| protein localization to organelle | GO:0033365 | 57 | 0.015 | |
| ribonucleoprotein complex biogenesis | GO:0022613 | 10 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 101 | 0.015 | |
| cellular homeostasis | GO:0019725 | 252 | 0.015 | |
| receptor mediated endocytosis | GO:0006898 | 42 | 0.014 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.014 | |
| regulation of intracellular protein transport | GO:0033157 | 34 | 0.014 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.014 | |
| positive regulation of neuron differentiation | GO:0045666 | 126 | 0.014 | |
| cell type specific apoptotic process | GO:0097285 | 134 | 0.014 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.014 | |
| protein localization to nucleus | GO:0034504 | 39 | 0.014 | |
| male gamete generation | GO:0048232 | 99 | 0.014 | |
| ossification | GO:0001503 | 70 | 0.014 | |
| gamete generation | GO:0007276 | 124 | 0.014 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.014 | |
| blood circulation | GO:0008015 | 183 | 0.014 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.014 | |
| regulation of cytoplasmic transport | GO:1903649 | 54 | 0.014 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 4 | 0.014 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.014 | |
| localization of cell | GO:0051674 | 202 | 0.014 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.013 | |
| positive regulation of cell differentiation | GO:0045597 | 217 | 0.013 | |
| response to oxygen levels | GO:0070482 | 265 | 0.013 | |
| transmembrane transport | GO:0055085 | 412 | 0.013 | |
| rna localization | GO:0006403 | 4 | 0.013 | |
| positive regulation of cell projection organization | GO:0031346 | 111 | 0.013 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.013 | |
| nucleosome organization | GO:0034728 | 1 | 0.013 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.013 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 55 | 0.012 | |
| response to metal ion | GO:0010038 | 253 | 0.012 | |
| regulation of interferon gamma production | GO:0032649 | 3 | 0.012 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.012 | |
| cell cycle process | GO:0022402 | 57 | 0.012 | |
| reactive nitrogen species metabolic process | GO:2001057 | 1 | 0.012 | |
| response to hypoxia | GO:0001666 | 231 | 0.012 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 32 | 0.012 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.012 | |
| anterior posterior pattern specification | GO:0009952 | 1 | 0.012 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.012 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.012 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 3 | 0.012 | |
| response to estrogen | GO:0043627 | 232 | 0.012 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.012 | |
| microtubule based process | GO:0007017 | 36 | 0.012 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 26 | 0.011 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 83 | 0.011 | |
| protein modification by small protein conjugation | GO:0032446 | 31 | 0.011 | |
| toxin transport | GO:1901998 | 3 | 0.011 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 35 | 0.011 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.011 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.011 | |
| signal release | GO:0023061 | 145 | 0.011 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 5 | 0.011 | |
| regulation of neuron death | GO:1901214 | 115 | 0.011 | |
| cell motility | GO:0048870 | 202 | 0.011 | |
| male mating behavior | GO:0060179 | 3 | 0.011 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.011 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.010 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.010 | |
| b cell activation involved in immune response | GO:0002312 | 1 | 0.010 | |
| regulation of cardiac muscle contraction | GO:0055117 | 17 | 0.010 | |
| regulation of molecular function | GO:0065009 | 398 | 0.010 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 80 | 0.010 | |
| tissue development | GO:0009888 | 252 | 0.010 | |
| cellular response to cytokine stimulus | GO:0071345 | 127 | 0.010 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 75 | 0.010 | |
| cell cell signaling | GO:0007267 | 335 | 0.010 | |
| chemosensory behavior | GO:0007635 | 2 | 0.010 | |
| triglyceride homeostasis | GO:0070328 | 2 | 0.010 | |