Rattus norvegicus

37 known processes

Cdkn1b

cyclin-dependent kinase inhibitor 1B

(Aliases: p27,P27KIP1,Kip1,Cdki1b,CDKN4)

Cdkn1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nucleic acid templated transcriptionGO:19035063800.212
positive regulation of cellular biosynthetic processGO:00313282950.165
transcription dna templatedGO:00063513770.152
rna biosynthetic processGO:00327743800.150
nucleic acid templated transcriptionGO:00976593790.142
rna metabolic processGO:00160704060.121
positive regulation of biosynthetic processGO:00098913190.118
positive regulation of macromolecule biosynthetic processGO:00105572470.115
regulation of rna metabolic processGO:00512523910.112
cellular response to oxygen containing compoundGO:19017013860.112
positive regulation of nucleobase containing compound metabolic processGO:00459353190.104
positive regulation of nitrogen compound metabolic processGO:00511733340.104
negative regulation of metabolic processGO:00098923310.104
regulation of transcription dna templatedGO:00063553740.103
regulation of phosphate metabolic processGO:00192203490.096
cellular component biogenesisGO:00440853680.096
positive regulation of rna biosynthetic processGO:19026801970.088
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.087
negative regulation of rna metabolic processGO:00512531230.087
transcription from rna polymerase ii promoterGO:00063662520.086
regulation of rna biosynthetic processGO:20011413810.086
regulation of cellular protein metabolic processGO:00322682670.081
negative regulation of macromolecule metabolic processGO:00106052600.079
response to metal ionGO:00100382530.078
regulation of transcription from rna polymerase ii promoterGO:00063572340.078
cellular response to stressGO:00335542690.077
negative regulation of biosynthetic processGO:00098901680.077
regulation of cell differentiationGO:00455953200.077
response to inorganic substanceGO:00100353770.077
negative regulation of gene expressionGO:00106291990.074
regulation of cell proliferationGO:00421273590.072
positive regulation of gene expressionGO:00106282440.072
cellular amino acid metabolic processGO:00065201070.072
negative regulation of cellular metabolic processGO:00313242810.071
positive regulation of transcription dna templatedGO:00458931970.071
cellular component movementGO:00069282480.069
negative regulation of macromolecule biosynthetic processGO:00105581480.068
regulation of molecular functionGO:00650093980.067
oxoacid metabolic processGO:00434362900.067
single organism biosynthetic processGO:00447113420.066
positive regulation of rna metabolic processGO:00512542030.064
cell migrationGO:00164771970.061
organic acid metabolic processGO:00060822920.060
regulation of phosphorylationGO:00423252480.060
cellular component assemblyGO:00226073600.059
positive regulation of multicellular organismal processGO:00512403870.057
response to extracellular stimulusGO:00099913800.056
negative regulation of nitrogen compound metabolic processGO:00511721610.054
cell projection organizationGO:00300303020.053
neuron projection developmentGO:00311752730.053
carboxylic acid metabolic processGO:00197522890.053
positive regulation of nucleic acid templated transcriptionGO:19035081970.052
regulation of apoptotic processGO:00429813350.052
regulation of multicellular organismal developmentGO:20000263760.051
regulation of protein metabolic processGO:00512462890.051
neuron developmentGO:00486662860.049
negative regulation of nucleic acid templated transcriptionGO:19035071170.048
protein phosphorylationGO:00064683450.048
localization of cellGO:00516742020.048
neuron differentiationGO:00301823680.048
tissue developmentGO:00098882520.046
response to temperature stimulusGO:0009266940.046
response to estradiolGO:00323551640.044
cellular response to endogenous stimulusGO:00714953770.044
positive regulation of phosphate metabolic processGO:00459372620.044
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.044
regulation of cellular component organizationGO:00511283680.044
macromolecular complex subunit organizationGO:00439333390.043
agingGO:00075682410.043
reproductive processGO:00224143720.043
response to monosaccharideGO:00342841590.043
regulation of catalytic activityGO:00507903040.043
intracellular signal transductionGO:00355563140.043
regulation of nervous system developmentGO:00519602640.042
nucleobase containing small molecule metabolic processGO:00550863160.042
organelle organizationGO:00069962660.041
protein complex biogenesisGO:00702712630.041
macromolecular complex assemblyGO:00650032730.041
cellular component morphogenesisGO:00329891550.041
regulation of protein modification processGO:00313991940.040
regulation of phosphorus metabolic processGO:00511743490.040
negative regulation of rna biosynthetic processGO:19026791180.040
protein complex assemblyGO:00064612630.039
secretionGO:00469033070.039
regulation of cell developmentGO:00602842630.039
negative regulation of nucleobase containing compound metabolic processGO:00459341530.039
positive regulation of cellular component organizationGO:00511302000.039
locomotionGO:00400112370.038
regulation of signal transductionGO:00099663180.038
response to nutrient levelsGO:00316673700.038
regulation of cellular localizationGO:00603412630.038
regulation of neuron differentiationGO:00456642080.037
cellular catabolic processGO:00442482950.037
positive regulation of protein metabolic processGO:00512471780.037
programmed cell deathGO:00125013920.037
regulation of programmed cell deathGO:00430673410.036
negative regulation of transcription dna templatedGO:00458921160.036
cell motilityGO:00488702020.036
response to corticosteroidGO:00319602350.036
regulation of neurogenesisGO:00507672470.036
positive regulation of cell proliferationGO:00082842490.036
cellular response to organonitrogen compoundGO:00714171970.036
cellular ketone metabolic processGO:0042180510.036
response to radiationGO:00093141370.036
response to nutrientGO:00075842480.036
positive regulation of developmental processGO:00510942830.035
cellular response to nitrogen compoundGO:19016992100.035
regulation of intracellular signal transductionGO:19025312180.035
response to woundingGO:00096112540.035
defense responseGO:00069521940.034
carbohydrate derivative metabolic processGO:19011353460.034
negative regulation of cellular biosynthetic processGO:00313271610.033
positive regulation of cell differentiationGO:00455972170.033
organophosphate metabolic processGO:00196373700.033
response to carbohydrateGO:00097431830.033
response to external biotic stimulusGO:00432072210.033
intracellular transportGO:00469071850.033
negative regulation of multicellular organismal processGO:00512412030.033
anatomical structure morphogenesisGO:00096532980.033
response to growth factorGO:00708481890.033
response to biotic stimulusGO:00096072260.032
protein complex subunit organizationGO:00718223020.032
homeostatic processGO:00425923310.032
positive regulation of molecular functionGO:00440932300.032
single organism organelle organizationGO:19025891800.032
positive regulation of phosphorus metabolic processGO:00105622620.032
nucleotide metabolic processGO:00091172790.031
establishment of protein localizationGO:00451841410.031
response to ketoneGO:19016541820.031
secretion by cellGO:00329402480.031
cellular response to organic cyclic compoundGO:00714072020.031
regulation of protein phosphorylationGO:00019321830.031
central nervous system developmentGO:00074173110.031
anterior posterior pattern specificationGO:000995210.030
apoptotic processGO:00069153810.030
response to peptideGO:19016522920.030
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.030
cellular response to growth factor stimulusGO:00713631620.030
amine metabolic processGO:0009308380.030
response to cytokineGO:00340972150.030
positive regulation of neuron differentiationGO:00456661260.030
positive regulation of cell developmentGO:00107201760.030
response to glucocorticoidGO:00513842230.029
response to estrogenGO:00436272320.029
response to hypoxiaGO:00016662310.029
response to glucoseGO:00097491360.029
nucleoside phosphate metabolic processGO:00067532830.028
brain developmentGO:00074202470.028
cation transportGO:00068123820.028
protein localizationGO:00081041910.028
positive regulation of nervous system developmentGO:00519621780.028
protein oligomerizationGO:00512591910.028
multi organism reproductive processGO:00447032620.028
cellular response to cytokine stimulusGO:00713451270.027
positive regulation of cellular protein metabolic processGO:00322701670.027
regulation of cellular ketone metabolic processGO:0010565270.027
cellular amine metabolic processGO:0044106380.027
lipid metabolic processGO:00066292830.027
head developmentGO:00603222470.027
organic substance catabolic processGO:19015753160.027
purine nucleotide metabolic processGO:00061632290.027
cell cell signalingGO:00072673350.027
negative regulation of cell deathGO:00605482290.027
negative regulation of cell proliferationGO:00082851190.027
response to campGO:0051591910.026
positive regulation of neurogenesisGO:00507691650.026
positive regulation of transportGO:00510502450.026
negative regulation of developmental processGO:00510931250.026
positive regulation of cell deathGO:00109421840.026
multicellular organism reproductionGO:00325042330.026
regulation of secretion by cellGO:19035302080.026
organophosphate biosynthetic processGO:00904071430.026
single organism catabolic processGO:00447122830.026
protein transportGO:00150311320.026
organonitrogen compound catabolic processGO:19015651790.025
regenerationGO:00310991630.025
positive regulation of apoptotic processGO:00430651540.025
cellular response to lipidGO:00713962010.025
regulation of secretionGO:00510462240.025
purine containing compound metabolic processGO:00725212530.025
regulation of cell projection organizationGO:00313441750.025
response to molecule of bacterial originGO:00022371940.024
positive regulation of phosphorylationGO:00423271770.024
response to bacteriumGO:00096172000.024
positive regulation of neuron projection developmentGO:0010976990.024
macromolecule localizationGO:00330362520.024
response to oxidative stressGO:00069791860.024
cellular lipid metabolic processGO:00442552080.024
positive regulation of cell projection organizationGO:00313461110.024
catabolic processGO:00090563510.023
response to lipopolysaccharideGO:00324961910.023
transmembrane transportGO:00550854120.023
chemical homeostasisGO:00488782920.023
cellular response to hormone stimulusGO:00328702470.023
regulation of cellular amine metabolic processGO:003323880.023
response to acid chemicalGO:00011012220.023
cellular macromolecule localizationGO:00707271220.023
regulation of mapk cascadeGO:00434081160.023
response to toxic substanceGO:00096361330.023
response to hydrogen peroxideGO:0042542890.023
positive regulation of cell communicationGO:00106472710.023
cellular protein localizationGO:00346131220.022
organonitrogen compound biosynthetic processGO:19015661670.022
response to mechanical stimulusGO:00096121340.022
response to hexoseGO:00097461440.022
negative regulation of protein metabolic processGO:00512481140.022
wound healingGO:00420601220.022
positive regulation of catalytic activityGO:00430851840.022
regulation of system processGO:00440572080.022
positive regulation of programmed cell deathGO:00430681570.022
positive regulation of protein modification processGO:00314011420.022
behaviorGO:00076102050.022
negative regulation of apoptotic processGO:00430661810.022
positive regulation of response to stimulusGO:00485842850.022
regulation of kinase activityGO:00435491170.021
ion transmembrane transportGO:00342203650.021
synaptic transmissionGO:00072682350.021
negative regulation of programmed cell deathGO:00430691830.021
nitrogen compound transportGO:00717052290.021
response to ethanolGO:00454711620.021
multicellular organismal reproductive processGO:00486092330.021
purine ribonucleotide metabolic processGO:00091502270.021
regulation of protein localizationGO:0032880810.021
mapk cascadeGO:00001651400.021
regulation of cell migrationGO:00303341280.021
single organism reproductive processGO:00447022970.021
cellular homeostasisGO:00197252520.021
positive regulation of signalingGO:00230562700.021
lipid biosynthetic processGO:00086101280.020
cell morphogenesisGO:00009021420.020
purine ribonucleoside metabolic processGO:00461281680.020
regulation of protein kinase activityGO:00458591050.020
multi multicellular organism processGO:00447061380.020
regulation of locomotionGO:00400121480.020
intracellular protein transportGO:0006886790.020
regulation of neuron projection developmentGO:00109751610.020
positive regulation of signal transductionGO:00099671750.020
ribonucleotide metabolic processGO:00092592310.020
cellular response to peptideGO:19016531330.020
response to other organismGO:00517072200.019
chemotaxisGO:0006935660.019
ribose phosphate metabolic processGO:00196932350.019
cellular chemical homeostasisGO:00550822470.019
signal transduction by phosphorylationGO:00230141440.019
regulation of cell motilityGO:20001451310.019
response to peptide hormoneGO:00434342780.019
reproductive structure developmentGO:00486081280.019
regulation of cellular amino acid metabolic processGO:000652120.019
response to decreased oxygen levelsGO:00362932370.019
growthGO:00400071650.019
single organism intracellular transportGO:19025821660.019
response to organophosphorusGO:00466831020.019
regulation of transferase activityGO:00513381230.019
regulation of hydrolase activityGO:00513361430.018
proteolysisGO:00065081750.018
regulation of hormone levelsGO:00108171870.018
regulation of cellular component movementGO:00512701500.018
heterocycle catabolic processGO:00467001670.018
positive regulation of intracellular signal transductionGO:19025331380.018
organic cyclic compound catabolic processGO:19013611750.018
response to reactive oxygen speciesGO:00003021200.018
metal ion homeostasisGO:00550651860.018
response to vitaminGO:00332731310.018
organic acid biosynthetic processGO:0016053830.018
tube developmentGO:0035295890.018
epithelium developmentGO:0060429960.018
immune system processGO:00023762040.017
dna metabolic processGO:0006259960.017
nucleotide catabolic processGO:00091661390.017
gland developmentGO:00487321550.017
developmental process involved in reproductionGO:00030061590.017
circulatory system developmentGO:00723591340.017
positive regulation of secretion by cellGO:19035321280.017
peptidyl amino acid modificationGO:00181931260.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
cytoplasmic transportGO:00164821150.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
inflammatory responseGO:00069541500.017
negative regulation of response to stimulusGO:00485851550.016
nucleoside metabolic processGO:00091161790.016
kidney developmentGO:0001822670.016
negative regulation of signalingGO:00230571570.016
urogenital system developmentGO:0001655780.016
cellular nitrogen compound catabolic processGO:00442701630.016
ribonucleoside metabolic processGO:00091191740.016
blood circulationGO:00080151830.016
divalent metal ion transportGO:00708381320.016
negative regulation of cell differentiationGO:0045596990.016
positive regulation of protein phosphorylationGO:00019341350.016
cellular response to peptide hormone stimulusGO:00713751200.016
vesicle mediated transportGO:00161921810.016
embryonic pattern specificationGO:000988010.016
axis specificationGO:000979840.016
divalent inorganic cation transportGO:00725111340.016
cell cycleGO:00070491010.016
cation homeostasisGO:00550801950.015
regulation of immune system processGO:00026821230.015
b cell differentiationGO:003018320.015
regulation of nucleotide metabolic processGO:00061401170.015
response to purine containing compoundGO:00140741260.015
positive regulation of cell migrationGO:0030335960.015
carbohydrate derivative catabolic processGO:19011361470.015
response to tumor necrosis factorGO:0034612560.015
nucleoside phosphate biosynthetic processGO:19012931020.015
axon developmentGO:0061564960.015
response to amino acidGO:0043200750.015
nucleoside phosphate catabolic processGO:19012921400.015
regulation of ion transportGO:00432692450.015
cardiovascular system developmentGO:00723581340.015
metal ion transportGO:00300012890.015
ion homeostasisGO:00508012120.015
reproductionGO:00000032450.015
cellular modified amino acid metabolic processGO:0006575610.015
positive regulation of cellular amine metabolic processGO:003324030.015
rhythmic processGO:00485111560.015
carbohydrate derivative biosynthetic processGO:19011371240.014
calcium ion homeostasisGO:00550741620.014
multicellular organismal signalingGO:0035637440.014
cellular metal ion homeostasisGO:00068751720.014
circulatory system processGO:00030131830.014
negative regulation of signal transductionGO:0009968830.014
dephosphorylationGO:0016311980.014
response to transition metal nanoparticleGO:19902671220.014
cell growthGO:00160491040.014
neurological system processGO:00508772190.014
sexual reproductionGO:00199531480.014
neuronal action potentialGO:0019228350.014
single organism cellular localizationGO:19025801020.014
small gtpase mediated signal transductionGO:0007264360.014
heart morphogenesisGO:000300730.014
carboxylic acid biosynthetic processGO:0046394830.014
membrane organizationGO:0061024940.014
divalent inorganic cation homeostasisGO:00725071650.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
purine ribonucleoside catabolic processGO:00461301240.014
action potentialGO:0001508540.014
cation transmembrane transportGO:00986552630.014
neuron deathGO:00709971270.014
positive regulation of ion transportGO:0043270940.014
cell part morphogenesisGO:00329901230.014
positive regulation of cellular component movementGO:00512721020.014
negative regulation of cellular protein metabolic processGO:00322691060.014
regulation of metal ion transportGO:00109591180.014
cellular cation homeostasisGO:00300031800.014
calcium ion transportGO:00068161310.014
purine containing compound catabolic processGO:00725231380.014
organophosphate catabolic processGO:00464341480.014
regulation of membrane potentialGO:00423911100.014
cell morphogenesis involved in differentiationGO:00009041190.013
negative regulation of phosphorus metabolic processGO:0010563800.013
female pregnancyGO:00075651220.013
negative regulation of phosphate metabolic processGO:0045936800.013
ribonucleotide catabolic processGO:00092611360.013
synaptic growth at neuromuscular junctionGO:005112410.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
ossificationGO:0001503700.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
aromatic compound catabolic processGO:00194391680.013
cellular response to external stimulusGO:00714961180.013
gastrulationGO:000736920.013
meiotic cell cycle processGO:190304630.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
purine nucleotide catabolic processGO:00061951360.013
inorganic cation transmembrane transportGO:00986622020.013
ras protein signal transductionGO:0007265290.013
cytoskeleton organizationGO:00070101110.013
purine nucleoside catabolic processGO:00061521240.013
cognitionGO:0050890920.013
positive regulation of secretionGO:00510471400.013
nucleoside catabolic processGO:00091641260.012
regulation of homeostatic processGO:00328441010.012
organ regenerationGO:00311001010.012
cellular response to oxidative stressGO:0034599760.012
sulfur compound metabolic processGO:0006790700.012
hormone metabolic processGO:0042445690.012
regulation of purine nucleotide metabolic processGO:19005421150.012
hormone transportGO:00099141210.012
organic acid transportGO:00158491160.012
carbohydrate metabolic processGO:00059751300.012
negative regulation of molecular functionGO:00440921330.012
purine nucleoside metabolic processGO:00422781690.012
ribonucleoside catabolic processGO:00424541260.012
response to insulinGO:00328681330.012
protein homooligomerizationGO:0051260910.012
eye morphogenesisGO:004859240.012
negative regulation of transportGO:00510511360.012
cellular amide metabolic processGO:0043603440.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
muscle cell proliferationGO:0033002840.012
negative regulation of cell communicationGO:00106481580.012
regulation of blood circulationGO:19035221100.012
reactive oxygen species biosynthetic processGO:190340980.012
circadian rhythmGO:0007623880.012
muscle structure developmentGO:0061061870.012
regulation of response to stressGO:00801341260.012
positive regulation of cell motilityGO:2000147970.012
gliogenesisGO:0042063930.012
response to axon injuryGO:0048678590.011
cellular calcium ion homeostasisGO:00068741600.011
chemosensory behaviorGO:000763520.011
response to amineGO:0014075460.011
signal releaseGO:00230611450.011
posttranscriptional regulation of gene expressionGO:0010608370.011
small molecule biosynthetic processGO:00442831240.011
negative regulation of nervous system developmentGO:0051961790.011
learning or memoryGO:0007611900.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
monocarboxylic acid metabolic processGO:00327871520.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
nucleotide biosynthetic processGO:0009165980.011
peptide biosynthetic processGO:004304330.011
cellular ion homeostasisGO:00068731840.011
g protein coupled receptor signaling pathwayGO:00071862420.011
positive regulation of locomotionGO:00400171020.011
response to heatGO:0009408600.011
inorganic ion transmembrane transportGO:00986602290.011
hepaticobiliary system developmentGO:0061008900.011
negative regulation of cell cycle phase transitionGO:190198840.011
positive regulation of transferase activityGO:0051347810.011
regulation of ion transmembrane transportGO:00347651210.011
maintenance of locationGO:0051235170.011
regulation of cell cycleGO:0051726730.011
cellular response to alcoholGO:0097306870.011
mitotic cell cycleGO:0000278490.011
hematopoietic progenitor cell differentiationGO:000224420.011
single organism membrane organizationGO:0044802740.011
lipid storageGO:001991510.011
antigen receptor mediated signaling pathwayGO:005085110.011
multicellular organism growthGO:003526410.010
negative regulation of catalytic activityGO:00430861030.010
protein importGO:0017038370.010
oxidation reduction processGO:00551143040.010
negative regulation of secretionGO:0051048820.010
regulation of growthGO:00400081050.010
glycosyl compound catabolic processGO:19016581260.010
cell adhesionGO:00071551100.010
regulation of cellular component biogenesisGO:0044087860.010
response to interleukin 1GO:0070555550.010
activation of cysteine type endopeptidase activityGO:009720240.010
response to retinoic acidGO:0032526630.010
defense response to gram negative bacteriumGO:005082930.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
glycosyl compound metabolic processGO:19016571820.010
response to calcium ionGO:0051592590.010
anion transportGO:00068201780.010
olfactory behaviorGO:004204820.010
spermatogenesisGO:0007283990.010

Cdkn1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
musculoskeletal system diseaseDOID:1700.012
disease of metabolismDOID:001466700.012
central nervous system diseaseDOID:33100.011