IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Klc3

kinesin light chain 3

(Aliases: MGC114264,Klct)

Ensembl: ENSRNOG00000018101
RGD: 621432
Entrez: 171549
UniProtKB: Q68G30

Process Predictions
Disease Predictions

Klc3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to acid chemical	GO:0001101	222	0.072
response to metal ion	GO:0010038	253	0.051
cellular response to oxygen containing compound	GO:1901701	386	0.041
response to peptide	GO:1901652	292	0.041
response to peptide hormone	GO:0043434	278	0.041
rna biosynthetic process	GO:0032774	380	0.037
cell projection organization	GO:0030030	302	0.034	Worm
multicellular organismal signaling	GO:0035637	44	0.034
cellular response to insulin stimulus	GO:0032869	81	0.033
cellular response to peptide	GO:1901653	133	0.032
single organism reproductive process	GO:0044702	297	0.031	Fly
response to nutrient	GO:0007584	248	0.031
cellular response to acid chemical	GO:0071229	75	0.031
response to nutrient levels	GO:0031667	370	0.031
transmission of nerve impulse	GO:0019226	42	0.029
negative regulation of signaling	GO:0023057	157	0.029
tissue development	GO:0009888	252	0.029	Fly
neural crest cell differentiation	GO:0014033	2	0.028
multicellular organism reproduction	GO:0032504	233	0.027	Fly
cation transport	GO:0006812	382	0.026
response to inorganic substance	GO:0010035	377	0.026
cellular response to hormone stimulus	GO:0032870	247	0.026
cellular response to endogenous stimulus	GO:0071495	377	0.025
cellular response to nitrogen compound	GO:1901699	210	0.025
cell part morphogenesis	GO:0032990	123	0.025	Worm
response to purine containing compound	GO:0014074	126	0.025
regulation of nervous system development	GO:0051960	264	0.024
cell morphogenesis	GO:0000902	142	0.024	Worm
multi organism reproductive process	GO:0044703	262	0.024	Fly
response to oxidative stress	GO:0006979	186	0.023
protein complex biogenesis	GO:0070271	263	0.023
response to vitamin	GO:0033273	131	0.022
nucleic acid templated transcription	GO:0097659	379	0.022
transcription dna templated	GO:0006351	377	0.022
response to fatty acid	GO:0070542	65	0.021
heart morphogenesis	GO:0003007	3	0.021
regulation of neurogenesis	GO:0050767	247	0.021
response to glucocorticoid	GO:0051384	223	0.020
neuronal action potential	GO:0019228	35	0.020
tube development	GO:0035295	89	0.019
protein complex subunit organization	GO:0071822	302	0.019
cardiac chamber development	GO:0003205	1	0.019
regulation of rna metabolic process	GO:0051252	391	0.019
regulation of ion transport	GO:0043269	245	0.019
cellular response to organonitrogen compound	GO:0071417	197	0.019
cellular response to peptide hormone stimulus	GO:0071375	120	0.019
cellular component biogenesis	GO:0044085	368	0.019
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.018
negative regulation of transcription dna templated	GO:0045892	116	0.018
rna metabolic process	GO:0016070	406	0.018
regulation of nucleic acid templated transcription	GO:1903506	380	0.018
multicellular organismal reproductive process	GO:0048609	233	0.018	Fly
intracellular transport	GO:0046907	185	0.018	Mouse Rat
macromolecular complex assembly	GO:0065003	273	0.018
axis specification	GO:0009798	4	0.017
carbohydrate derivative metabolic process	GO:1901135	346	0.017
epithelial cell differentiation	GO:0030855	71	0.017	Fly
ion transmembrane transport	GO:0034220	365	0.016
epithelium development	GO:0060429	96	0.016	Fly
cilium morphogenesis	GO:0060271	2	0.016
response to camp	GO:0051591	91	0.016
negative regulation of cellular metabolic process	GO:0031324	281	0.016
action potential	GO:0001508	54	0.016
neuron projection development	GO:0031175	273	0.016	Worm
response to corticosteroid	GO:0031960	235	0.015
developmental process involved in reproduction	GO:0003006	159	0.015	Fly
protein complex assembly	GO:0006461	263	0.015
localization of cell	GO:0051674	202	0.015
cellular component assembly	GO:0022607	360	0.015
reproduction	GO:0000003	245	0.015	Worm Fly
positive regulation of cellular component organization	GO:0051130	200	0.014
regulation of cell projection organization	GO:0031344	175	0.014
negative regulation of multicellular organismal process	GO:0051241	203	0.014
brain development	GO:0007420	247	0.014
regulation of rna biosynthetic process	GO:2001141	381	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.014
protein oligomerization	GO:0051259	191	0.014
neuron development	GO:0048666	286	0.014	Worm
cell morphogenesis involved in differentiation	GO:0000904	119	0.014	Worm
transmembrane transport	GO:0055085	412	0.014
organelle organization	GO:0006996	266	0.014	Worm
negative regulation of cell development	GO:0010721	82	0.014
gamete generation	GO:0007276	124	0.014	Fly
cell cycle	GO:0007049	101	0.013	Worm Fly
sensory perception of light stimulus	GO:0050953	3	0.013
gliogenesis	GO:0042063	93	0.013
sex differentiation	GO:0007548	113	0.013
negative regulation of macromolecule metabolic process	GO:0010605	260	0.013
regulation of transcription dna templated	GO:0006355	374	0.013
cation transmembrane transport	GO:0098655	263	0.013
cellular response to organic cyclic compound	GO:0071407	202	0.013
regulation of molecular function	GO:0065009	398	0.013
mitotic spindle organization	GO:0007052	2	0.013
embryonic pattern specification	GO:0009880	1	0.013
positive regulation of nervous system development	GO:0051962	178	0.013
development of primary sexual characteristics	GO:0045137	107	0.013
inorganic ion transmembrane transport	GO:0098660	229	0.013
cell motility	GO:0048870	202	0.013
spindle organization	GO:0007051	2	0.012
single organism organelle organization	GO:1902589	180	0.012	Worm
eye morphogenesis	GO:0048592	4	0.012
cellular component morphogenesis	GO:0032989	155	0.012	Worm Fly
auditory receptor cell differentiation	GO:0042491	2	0.012
central nervous system development	GO:0007417	311	0.012
salivary gland development	GO:0007431	3	0.012
bmp signaling pathway	GO:0030509	4	0.012
regulation of secretion by cell	GO:1903530	208	0.012
negative regulation of gene expression	GO:0010629	199	0.012
response to reactive oxygen species	GO:0000302	120	0.012
neurological system process	GO:0050877	219	0.012
mechanoreceptor differentiation	GO:0042490	2	0.012
regulation of cellular amino acid metabolic process	GO:0006521	2	0.012
negative regulation of cell communication	GO:0010648	158	0.012
amide transport	GO:0042886	105	0.012
negative regulation of cellular component organization	GO:0051129	83	0.012
response to extracellular stimulus	GO:0009991	380	0.011
male sex differentiation	GO:0046661	64	0.011
response to calcium ion	GO:0051592	59	0.011
neuron differentiation	GO:0030182	368	0.011	Worm
growth	GO:0040007	165	0.011	Worm
glial cell differentiation	GO:0010001	65	0.011
lens fiber cell differentiation	GO:0070306	3	0.011
chemical homeostasis	GO:0048878	292	0.011
response to growth factor	GO:0070848	189	0.011
visual perception	GO:0007601	3	0.011
reproductive process	GO:0022414	372	0.011	Fly
response to carbohydrate	GO:0009743	183	0.011
circadian rhythm	GO:0007623	88	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.011
neural crest cell development	GO:0014032	2	0.011
response to oxygen levels	GO:0070482	265	0.011
inner ear receptor cell differentiation	GO:0060113	2	0.010
negative regulation of cell differentiation	GO:0045596	99	0.010
cell migration	GO:0016477	197	0.010
regulation of bmp signaling pathway	GO:0030510	2	0.010
nucleobase containing small molecule metabolic process	GO:0055086	316	0.010
gonad development	GO:0008406	104	0.010
digestive tract development	GO:0048565	39	0.010
anterior posterior pattern specification	GO:0009952	1	0.010
positive regulation of cell projection organization	GO:0031346	111	0.010
reproductive system development	GO:0061458	128	0.010

Klc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
retinal disease	DOID:5679	0.100
eye and adnexa disease	DOID:1492	0.100
eye disease	DOID:5614	0.100
sensory system disease	DOID:0050155	0.100
disease of anatomical entity	DOID:7	0.100
nervous system disease	DOID:863	0.100
retinal degeneration	DOID:8466	0.036
urinary system disease	DOID:18	0.024
kidney disease	DOID:557	0.024
retinitis pigmentosa	DOID:10584	0.021
musculoskeletal system disease	DOID:17	0.013
bone disease	DOID:0080001	0.013
connective tissue disease	DOID:65	0.013
bone development disease	DOID:0080006	0.013

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