Rattus norvegicus

0 known processes

Map4k2

mitogen activated protein kinase kinase kinase kinase 2

Map4k2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of nitrogen compound metabolic processGO:00511733340.112
response to nutrient levelsGO:00316673700.090
transcription dna templatedGO:00063513770.077
regulation of molecular functionGO:00650093980.076
Human
regulation of protein metabolic processGO:00512462890.070
Human
positive regulation of signalingGO:00230562700.068
Human
chemical homeostasisGO:00488782920.064
response to peptideGO:19016522920.064
regulation of cell differentiationGO:00455953200.062
positive regulation of catalytic activityGO:00430851840.058
Human
rna metabolic processGO:00160704060.058
regulation of rna metabolic processGO:00512523910.057
positive regulation of biosynthetic processGO:00098913190.054
transcription from rna polymerase ii promoterGO:00063662520.052
central nervous system developmentGO:00074173110.052
homeostatic processGO:00425923310.051
positive regulation of rna metabolic processGO:00512542030.047
cation transportGO:00068123820.047
rna biosynthetic processGO:00327743800.045
regulation of cellular localizationGO:00603412630.045
regulation of ion transportGO:00432692450.045
intracellular signal transductionGO:00355563140.044
Human
ion homeostasisGO:00508012120.044
positive regulation of developmental processGO:00510942830.044
reproductive processGO:00224143720.043
response to extracellular stimulusGO:00099913800.042
regulation of catalytic activityGO:00507903040.041
Human
positive regulation of molecular functionGO:00440932300.041
Human
blood circulationGO:00080151830.040
positive regulation of transcription dna templatedGO:00458931970.040
response to glucocorticoidGO:00513842230.040
single organism reproductive processGO:00447022970.039
enzyme linked receptor protein signaling pathwayGO:00071671160.038
vesicle mediated transportGO:00161921810.038
regulation of multicellular organismal developmentGO:20000263760.037
regulation of phosphate metabolic processGO:00192203490.037
Human
tissue developmentGO:00098882520.036
cell cell signalingGO:00072673350.036
regulation of nucleic acid templated transcriptionGO:19035063800.035
positive regulation of cell differentiationGO:00455972170.035
nucleic acid templated transcriptionGO:00976593790.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
positive regulation of cellular protein metabolic processGO:00322701670.034
Human
cellular response to peptide hormone stimulusGO:00713751200.034
brain developmentGO:00074202470.034
neuron differentiationGO:00301823680.034
nitrogen compound transportGO:00717052290.034
regulation of cell proliferationGO:00421273590.033
positive regulation of rna biosynthetic processGO:19026801970.033
regulation of phosphorus metabolic processGO:00511743490.032
Human
positive regulation of gene expressionGO:00106282440.032
positive regulation of neurogenesisGO:00507691650.032
protein phosphorylationGO:00064683450.032
Human
developmental process involved in reproductionGO:00030061590.032
agingGO:00075682410.031
organophosphate metabolic processGO:00196373700.031
amine metabolic processGO:0009308380.031
positive regulation of cell proliferationGO:00082842490.031
positive regulation of multicellular organismal processGO:00512403870.030
response to peptide hormoneGO:00434342780.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
regulation of transcription dna templatedGO:00063553740.029
regulation of response to stressGO:00801341260.028
Human
circulatory system processGO:00030131830.028
response to toxic substanceGO:00096361330.028
positive regulation of protein metabolic processGO:00512471780.028
Human
negative regulation of macromolecule metabolic processGO:00106052600.028
endothelium developmentGO:0003158120.028
response to transition metal nanoparticleGO:19902671220.027
defense responseGO:00069521940.027
programmed cell deathGO:00125013920.027
g protein coupled receptor signaling pathwayGO:00071862420.027
ion transmembrane transportGO:00342203650.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
anatomical structure morphogenesisGO:00096532980.026
multi organism reproductive processGO:00447032620.026
regulation of rna biosynthetic processGO:20011413810.026
response to ketoneGO:19016541820.026
localization of cellGO:00516742020.025
regulation of nervous system developmentGO:00519602640.025
organic acid metabolic processGO:00060822920.025
negative regulation of metabolic processGO:00098923310.025
lipid metabolic processGO:00066292830.024
positive regulation of cellular biosynthetic processGO:00313282950.024
response to oxygen levelsGO:00704822650.024
carbohydrate derivative metabolic processGO:19011353460.024
regulation of cellular protein metabolic processGO:00322682670.024
Human
regenerationGO:00310991630.024
positive regulation of phosphate metabolic processGO:00459372620.023
Human
organelle organizationGO:00069962660.023
positive regulation of response to stimulusGO:00485842850.023
Human
gland developmentGO:00487321550.023
regulation of neurogenesisGO:00507672470.023
regulation of cell developmentGO:00602842630.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
response to biotic stimulusGO:00096072260.022
cellular response to organonitrogen compoundGO:00714171970.022
gamete generationGO:00072761240.022
multicellular organismal reproductive processGO:00486092330.022
nucleobase containing small molecule metabolic processGO:00550863160.022
cell migrationGO:00164771970.021
apoptotic processGO:00069153810.021
regulation of anatomical structure morphogenesisGO:00226031410.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
rhythmic processGO:00485111560.021
regulation of phosphatidylinositol dephosphorylationGO:006030410.021
regulation of hydrolase activityGO:00513361430.021
head developmentGO:00603222470.021
macromolecule localizationGO:00330362520.021
secretion by cellGO:00329402480.021
female pregnancyGO:00075651220.021
cellular response to endogenous stimulusGO:00714953770.020
neuron projection developmentGO:00311752730.020
negative regulation of innate immune responseGO:004582440.020
negative regulation of signalingGO:00230571570.020
regulation of endothelial cell differentiationGO:004560140.020
cellular response to peptideGO:19016531330.020
secretionGO:00469033070.020
cellular response to stressGO:00335542690.019
Human
response to mechanical stimulusGO:00096121340.019
cellular chemical homeostasisGO:00550822470.019
positive regulation of nervous system developmentGO:00519621780.019
negative regulation of cell deathGO:00605482290.019
response to inorganic substanceGO:00100353770.019
positive regulation of cell developmentGO:00107201760.019
metal ion homeostasisGO:00550651860.019
negative regulation of gene expressionGO:00106291990.019
single organism biosynthetic processGO:00447113420.019
regulation of signal transductionGO:00099663180.019
Human
cellular ketone metabolic processGO:0042180510.019
cellular amine metabolic processGO:0044106380.019
response to nutrientGO:00075842480.018
regulation of cell growthGO:0001558850.018
regulation of secretion by cellGO:19035302080.018
regulation of cellular component organizationGO:00511283680.018
reproductionGO:00000032450.018
cellular amino acid metabolic processGO:00065201070.018
organ regenerationGO:00311001010.018
peptide transportGO:0015833970.018
cellular component movementGO:00069282480.018
regulation of kinase activityGO:00435491170.018
Human
intracellular transportGO:00469071850.018
behaviorGO:00076102050.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
regulation of peptide transportGO:0090087870.017
negative regulation of cellular metabolic processGO:00313242810.017
circulatory system developmentGO:00723591340.017
tube developmentGO:0035295890.017
regulation of cellular amino acid metabolic processGO:000652120.017
negative regulation of cell differentiationGO:0045596990.017
negative regulation of multicellular organismal processGO:00512412030.017
response to hexoseGO:00097461440.017
small gtpase mediated signal transductionGO:0007264360.017
embryonic pattern specificationGO:000988010.017
cellular catabolic processGO:00442482950.016
peptide secretionGO:0002790860.016
response to ethanolGO:00454711620.016
cellular component biogenesisGO:00440853680.016
negative regulation of apoptotic processGO:00430661810.016
response to decreased oxygen levelsGO:00362932370.016
organic acid transportGO:00158491160.016
cellular response to nitrogen compoundGO:19016992100.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
ribonucleotide metabolic processGO:00092592310.016
response to cytokineGO:00340972150.016
negative regulation of response to stimulusGO:00485851550.016
oxoacid metabolic processGO:00434362900.016
immune system processGO:00023762040.016
regulation of synaptic transmissionGO:00508041410.016
growthGO:00400071650.016
response to other organismGO:00517072200.016
response to hypoxiaGO:00016662310.016
negative regulation of biosynthetic processGO:00098901680.016
mapk cascadeGO:00001651400.016
Human
single organism behaviorGO:00447081300.015
endothelial cell differentiationGO:004544690.015
regulation of cellular amine metabolic processGO:003323880.015
cell cycleGO:00070491010.015
nucleoside phosphate metabolic processGO:00067532830.015
cellular homeostasisGO:00197252520.015
synaptic transmissionGO:00072682350.015
forebrain developmentGO:0030900980.015
signal releaseGO:00230611450.015
signal transduction by phosphorylationGO:00230141440.015
Human
regulation of anatomical structure sizeGO:00900661350.015
negative regulation of cell communicationGO:00106481580.014
single organism intracellular transportGO:19025821660.014
regulation of neuron deathGO:19012141150.014
kidney developmentGO:0001822670.014
cellular component assemblyGO:00226073600.014
regulation of hormone levelsGO:00108171870.014
urogenital system developmentGO:0001655780.014
amide transportGO:00428861050.014
negative regulation of cellular biosynthetic processGO:00313271610.014
response to bacteriumGO:00096172000.014
neuromuscular synaptic transmissionGO:000727420.014
anion transmembrane transportGO:0098656770.014
regulation of cellular ketone metabolic processGO:0010565270.014
cell cell signaling involved in cell fate commitmentGO:004516820.014
carboxylic acid transportGO:00469421150.014
embryo developmentGO:0009790490.014
negative regulation of transportGO:00510511360.014
locomotionGO:00400112370.013
epithelium developmentGO:0060429960.013
response to alkaloidGO:00432791320.013
multicellular organism reproductionGO:00325042330.013
regulation of system processGO:00440572080.013
positive regulation of cell communicationGO:00106472710.013
Human
negative regulation of natural killer cell mediated immunityGO:000271640.013
cellular response to hormone stimulusGO:00328702470.013
response to woundingGO:00096112540.013
sexual reproductionGO:00199531480.013
heart morphogenesisGO:000300730.013
metal ion transportGO:00300012890.013
calcium ion homeostasisGO:00550741620.013
ras protein signal transductionGO:0007265290.013
carboxylic acid metabolic processGO:00197522890.013
neuron deathGO:00709971270.013
anterior posterior pattern specificationGO:000995210.013
nucleoside metabolic processGO:00091161790.013
positive regulation of phosphorus metabolic processGO:00105622620.013
Human
muscle structure developmentGO:0061061870.013
neuron developmentGO:00486662860.013
single organism organelle organizationGO:19025891800.013
renal system developmentGO:0072001670.013
action potentialGO:0001508540.013
catabolic processGO:00090563510.013
inflammatory responseGO:00069541500.012
ribose phosphate metabolic processGO:00196932350.012
inorganic ion transmembrane transportGO:00986602290.012
negative regulation of neuron deathGO:1901215690.012
axis specificationGO:000979840.012
cell cycle checkpointGO:000007520.012
positive regulation of cellular amine metabolic processGO:003324030.012
cellular component morphogenesisGO:00329891550.012
steroid metabolic processGO:0008202730.012
response to external biotic stimulusGO:00432072210.012
cell morphogenesisGO:00009021420.012
single organism catabolic processGO:00447122830.012
actin filament based processGO:0030029860.012
monovalent inorganic cation transportGO:00156721720.012
muscle cell differentiationGO:0042692520.012
protein localizationGO:00081041910.012
regulation of blood circulationGO:19035221100.012
organic cyclic compound catabolic processGO:19013611750.011
nucleotide metabolic processGO:00091172790.011
cell adhesionGO:00071551100.011
spindle organizationGO:000705120.011
response to estradiolGO:00323551640.011
positive regulation of protein modification processGO:00314011420.011
Human
response to vitaminGO:00332731310.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
cation homeostasisGO:00550801950.011
response to acid chemicalGO:00011012220.011
multi multicellular organism processGO:00447061380.011
cell projection organizationGO:00300303020.011
establishment of tissue polarityGO:000716420.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
regulation of body fluid levelsGO:0050878900.011
purine ribonucleotide metabolic processGO:00091502270.011
chromosome segregationGO:000705920.011
regulation of immune system processGO:00026821230.011
natural killer cell mediated immune response to tumor cellGO:000242310.011
cytoplasmic transportGO:00164821150.011
regulation of neuron differentiationGO:00456642080.011
regulation of notch signaling pathwayGO:000859330.011
regulation of cellular component biogenesisGO:0044087860.011
regulation of intracellular transportGO:0032386650.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
purine nucleoside metabolic processGO:00422781690.011
negative regulation of cellular protein metabolic processGO:00322691060.011
neuronal action potentialGO:0019228350.011
spermatogenesisGO:0007283990.011
cellular ion homeostasisGO:00068731840.011
cellular response to oxygen containing compoundGO:19017013860.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
cellular response to insulin stimulusGO:0032869810.010
response to insulinGO:00328681330.010
negative regulation of programmed cell deathGO:00430691830.010
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.010
embryonic axis specificationGO:000057810.010
positive regulation of nucleotide metabolic processGO:0045981910.010
positive regulation of cellular component organizationGO:00511302000.010
regulation of membrane potentialGO:00423911100.010
multicellular organismal signalingGO:0035637440.010
cardiovascular system developmentGO:00723581340.010
response to monosaccharideGO:00342841590.010
negative regulation of rna metabolic processGO:00512531230.010
positive regulation of neuron differentiationGO:00456661260.010

Map4k2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
kidney diseaseDOID:55700.016
urinary system diseaseDOID:1800.016
disease of anatomical entityDOID:700.016