Rattus norvegicus

0 known processes

Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

(Aliases: RGD1562028)

Map4k5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleic acid templated transcriptionGO:00976593790.185
rna metabolic processGO:00160704060.163
positive regulation of nucleobase containing compound metabolic processGO:00459353190.136
regulation of rna metabolic processGO:00512523910.135
positive regulation of nitrogen compound metabolic processGO:00511733340.118
rna biosynthetic processGO:00327743800.118
transcription dna templatedGO:00063513770.110
apoptotic processGO:00069153810.097
regulation of transcription dna templatedGO:00063553740.091
cellular component biogenesisGO:00440853680.079
regulation of nucleic acid templated transcriptionGO:19035063800.078
regulation of phosphorus metabolic processGO:00511743490.077
positive regulation of nucleic acid templated transcriptionGO:19035081970.074
transcription from rna polymerase ii promoterGO:00063662520.072
localization of cellGO:00516742020.068
macromolecular complex assemblyGO:00650032730.059
regulation of apoptotic processGO:00429813350.059
programmed cell deathGO:00125013920.057
neurological system processGO:00508772190.056
positive regulation of biosynthetic processGO:00098913190.055
regulation of rna biosynthetic processGO:20011413810.052
negative regulation of metabolic processGO:00098923310.052
protein phosphorylationGO:00064683450.051
Human
positive regulation of phosphorylationGO:00423271770.050
positive regulation of rna biosynthetic processGO:19026801970.049
cellular protein localizationGO:00346131220.049
regulation of molecular functionGO:00650093980.048
positive regulation of transcription dna templatedGO:00458931970.048
positive regulation of cellular biosynthetic processGO:00313282950.047
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729610.046
positive regulation of gene expressionGO:00106282440.046
locomotionGO:00400112370.045
cellular ketone metabolic processGO:0042180510.043
single organism reproductive processGO:00447022970.043
regulation of transcription from rna polymerase ii promoterGO:00063572340.041
developmental process involved in reproductionGO:00030061590.039
positive regulation of macromolecule biosynthetic processGO:00105572470.039
positive regulation of molecular functionGO:00440932300.039
negative regulation of cellular biosynthetic processGO:00313271610.038
regulation of cellular ketone metabolic processGO:0010565270.038
protein complex assemblyGO:00064612630.037
organophosphate metabolic processGO:00196373700.037
organic acid metabolic processGO:00060822920.037
oxoacid metabolic processGO:00434362900.037
cellular response to peptideGO:19016531330.037
negative regulation of macromolecule metabolic processGO:00106052600.036
negative regulation of apoptotic processGO:00430661810.036
regulation of signal transductionGO:00099663180.036
positive regulation of catalytic activityGO:00430851840.036
regulation of hormone levelsGO:00108171870.035
cellular response to endogenous stimulusGO:00714953770.035
macromolecular complex subunit organizationGO:00439333390.035
regulation of cellular component organizationGO:00511283680.034
tissue developmentGO:00098882520.034
negative regulation of cellular metabolic processGO:00313242810.034
protein complex biogenesisGO:00702712630.034
cell morphogenesis involved in neuron differentiationGO:00486671060.034
cell motilityGO:00488702020.033
positive regulation of protein metabolic processGO:00512471780.033
regulation of nervous system developmentGO:00519602640.033
positive regulation of rna metabolic processGO:00512542030.033
reproductive system developmentGO:00614581280.033
positive regulation of phosphorus metabolic processGO:00105622620.032
regulation of cell proliferationGO:00421273590.032
carboxylic acid metabolic processGO:00197522890.031
regulation of catalytic activityGO:00507903040.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.031
protein complex subunit organizationGO:00718223020.030
positive regulation of cell proliferationGO:00082842490.030
response to decreased oxygen levelsGO:00362932370.030
single organism cellular localizationGO:19025801020.030
response to extracellular stimulusGO:00099913800.029
response to nutrient levelsGO:00316673700.029
embryonic pattern specificationGO:000988010.029
cellular response to oxygen containing compoundGO:19017013860.029
positive regulation of signalingGO:00230562700.028
reproductive structure developmentGO:00486081280.028
positive regulation of cellular protein metabolic processGO:00322701670.028
cellular response to hormone stimulusGO:00328702470.027
catabolic processGO:00090563510.027
chemical homeostasisGO:00488782920.027
regulation of cellular localizationGO:00603412630.027
regulation of programmed cell deathGO:00430673410.027
negative regulation of cell deathGO:00605482290.027
positive regulation of phosphate metabolic processGO:00459372620.026
negative regulation of biosynthetic processGO:00098901680.026
vesicle mediated transportGO:00161921810.026
amine metabolic processGO:0009308380.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
nucleoside phosphate metabolic processGO:00067532830.026
reproductive processGO:00224143720.025
positive regulation of response to stimulusGO:00485842850.025
intracellular transportGO:00469071850.025
cellular component assemblyGO:00226073600.024
proteolysisGO:00065081750.024
sexual reproductionGO:00199531480.024
cell projection organizationGO:00300303020.024
g protein coupled receptor signaling pathwayGO:00071862420.024
cellular macromolecule localizationGO:00707271220.024
response to radiationGO:00093141370.024
cell migrationGO:00164771970.024
response to oxygen levelsGO:00704822650.023
lipid metabolic processGO:00066292830.023
regulation of secretionGO:00510462240.023
negative regulation of rna biosynthetic processGO:19026791180.023
cell cell signalingGO:00072673350.023
carbohydrate derivative catabolic processGO:19011361470.023
behaviorGO:00076102050.023
multicellular organismal reproductive processGO:00486092330.023
neuron differentiationGO:00301823680.023
secretion by cellGO:00329402480.023
transmembrane transportGO:00550854120.023
positive regulation of cytosolic calcium ion concentrationGO:00072041220.023
secretionGO:00469033070.023
cellular response to luteinizing hormone stimulusGO:007137350.022
dna metabolic processGO:0006259960.022
anatomical structure morphogenesisGO:00096532980.022
regulation of hydrolase activityGO:00513361430.022
response to ionizing radiationGO:0010212590.022
homeostatic processGO:00425923310.022
sex differentiationGO:00075481130.022
multicellular organism reproductionGO:00325042330.021
cell morphogenesis involved in differentiationGO:00009041190.021
regulation of cell developmentGO:00602842630.021
protein oligomerizationGO:00512591910.021
regulation of membrane potentialGO:00423911100.021
mesoderm developmentGO:000749820.021
cellular amino acid metabolic processGO:00065201070.021
positive regulation of protein phosphorylationGO:00019341350.021
regulation of cell differentiationGO:00455953200.021
regulation of cellular amino acid metabolic processGO:000652120.021
negative regulation of response to stimulusGO:00485851550.021
cellular amine metabolic processGO:0044106380.021
cation transportGO:00068123820.021
axis specificationGO:000979840.021
cellular component movementGO:00069282480.021
single organism intracellular transportGO:19025821660.020
purine ribonucleotide metabolic processGO:00091502270.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
non canonical wnt signaling pathwayGO:003556730.020
positive regulation of protein modification processGO:00314011420.020
response to growth factorGO:00708481890.020
response to temperature stimulusGO:0009266940.020
muscle structure developmentGO:0061061870.020
regulation of cellular protein metabolic processGO:00322682670.020
ribonucleotide biosynthetic processGO:0009260850.020
negative regulation of transcription dna templatedGO:00458921160.019
intracellular signal transductionGO:00355563140.019
Human
reproductionGO:00000032450.019
regulation of neuron differentiationGO:00456642080.019
purine containing compound metabolic processGO:00725212530.019
cellular calcium ion homeostasisGO:00068741600.019
regulation of protein metabolic processGO:00512462890.019
growthGO:00400071650.019
organic substance catabolic processGO:19015753160.019
cell projection morphogenesisGO:00488581230.019
macromolecule localizationGO:00330362520.019
regulation of cellular amine metabolic processGO:003323880.019
central nervous system developmentGO:00074173110.019
enzyme linked receptor protein signaling pathwayGO:00071671160.019
organophosphate biosynthetic processGO:00904071430.018
positive regulation of cell developmentGO:00107201760.018
organelle organizationGO:00069962660.018
negative regulation of multicellular organismal processGO:00512412030.018
protein localizationGO:00081041910.018
negative regulation of programmed cell deathGO:00430691830.018
response to peptide hormoneGO:00434342780.018
nucleobase containing small molecule metabolic processGO:00550863160.018
regulation of phosphate metabolic processGO:00192203490.018
cell cycleGO:00070491010.018
regulation of multicellular organismal developmentGO:20000263760.018
response to campGO:0051591910.018
multi organism reproductive processGO:00447032620.018
muscle cell proliferationGO:0033002840.018
cellular component morphogenesisGO:00329891550.018
positive regulation of developmental processGO:00510942830.017
protein heterooligomerizationGO:0051291890.017
positive regulation of cell deathGO:00109421840.017
positive regulation of immune system processGO:0002684900.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
camp biosynthetic processGO:0006171470.017
positive regulation of cell differentiationGO:00455972170.017
purine nucleotide metabolic processGO:00061632290.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
cytokine productionGO:0001816610.017
neuron projection developmentGO:00311752730.017
organ regenerationGO:00311001010.017
positive regulation of cellular amine metabolic processGO:003324030.016
response to peptideGO:19016522920.016
cellular homeostasisGO:00197252520.016
single organism biosynthetic processGO:00447113420.016
regenerationGO:00310991630.016
cell activationGO:0001775970.016
nucleotide metabolic processGO:00091172790.016
carbohydrate derivative metabolic processGO:19011353460.016
gamete generationGO:00072761240.016
ribose phosphate metabolic processGO:00196932350.016
cell morphogenesisGO:00009021420.016
cytoskeleton organizationGO:00070101110.016
positive regulation of transportGO:00510502450.015
regulation of neurogenesisGO:00507672470.015
negative regulation of gene expressionGO:00106291990.015
cellular response to stressGO:00335542690.015
anion transportGO:00068201780.015
cytoplasmic transportGO:00164821150.015
cation homeostasisGO:00550801950.015
response to external biotic stimulusGO:00432072210.015
lipid transportGO:0006869610.015
transmission of nerve impulseGO:0019226420.015
negative regulation of molecular functionGO:00440921330.015
small gtpase mediated signal transductionGO:0007264360.015
cellular response to abiotic stimulusGO:0071214850.015
neuron projection morphogenesisGO:00488121220.015
metal ion transportGO:00300012890.015
gland developmentGO:00487321550.015
positive regulation of ion transportGO:0043270940.015
rhythmic processGO:00485111560.015
organic anion transportGO:00157111320.015
metal ion homeostasisGO:00550651860.015
regulation of cellular component movementGO:00512701500.014
purine nucleotide biosynthetic processGO:0006164830.014
regulation of transferase activityGO:00513381230.014
cyclic nucleotide metabolic processGO:0009187800.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
cellular catabolic processGO:00442482950.014
anterior posterior pattern specificationGO:000995210.014
regulation of nucleotide metabolic processGO:00061401170.014
mapk cascadeGO:00001651400.014
cytosolic calcium ion homeostasisGO:00514801400.014
defense responseGO:00069521940.014
cell type specific apoptotic processGO:00972851340.014
head developmentGO:00603222470.014
cardiovascular system developmentGO:00723581340.014
positive regulation of apoptotic processGO:00430651540.014
cellular ion homeostasisGO:00068731840.014
response to purine containing compoundGO:00140741260.014
negative regulation of signalingGO:00230571570.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
purine ribonucleotide catabolic processGO:00091541360.013
dephosphorylationGO:0016311980.013
regulation of smooth muscle cell proliferationGO:0048660750.013
regulation of neuron projection developmentGO:00109751610.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
brain developmentGO:00074202470.013
cellular response to growth factor stimulusGO:00713631620.013
response to bacteriumGO:00096172000.013
positive regulation of cell communicationGO:00106472710.013
negative regulation of cell communicationGO:00106481580.013
positive regulation of purine nucleotide biosynthetic processGO:1900373360.013
cyclic purine nucleotide metabolic processGO:0052652620.013
potassium ion transportGO:0006813970.013
positive regulation of multicellular organismal processGO:00512403870.013
positive regulation of neuron differentiationGO:00456661260.013
peptidyl amino acid modificationGO:00181931260.013
divalent inorganic cation homeostasisGO:00725071650.013
development of primary sexual characteristicsGO:00451371070.013
positive regulation of neurogenesisGO:00507691650.013
organic acid transportGO:00158491160.013
response to other organismGO:00517072200.012
agingGO:00075682410.012
spindle organizationGO:000705120.012
embryonic axis specificationGO:000057810.012
multicellular organismal signalingGO:0035637440.012
hormone metabolic processGO:0042445690.012
cellular response to organonitrogen compoundGO:00714171970.012
response to mechanical stimulusGO:00096121340.012
positive regulation of secretion by cellGO:19035321280.012
camp metabolic processGO:0046058630.012
cellular chemical homeostasisGO:00550822470.012
response to biotic stimulusGO:00096072260.012
nucleotide biosynthetic processGO:0009165980.012
nucleobase containing compound catabolic processGO:00346551520.012
positive regulation of intracellular signal transductionGO:19025331380.012
regulation of secretion by cellGO:19035302080.012
hexose transportGO:0008645290.012
protein processingGO:0016485680.012
hormone secretionGO:00468791150.012
gonad developmentGO:00084061040.011
intracellular protein transportGO:0006886790.011
cellular response to peptide hormone stimulusGO:00713751200.011
response to gamma radiationGO:0010332240.011
ribonucleotide catabolic processGO:00092611360.011
smooth muscle cell proliferationGO:0048659770.011
neuron developmentGO:00486662860.011
endocytosisGO:0006897840.011
amide transportGO:00428861050.011
regulation of cell motilityGO:20001451310.011
response to acid chemicalGO:00011012220.011
regulation of protein modification processGO:00313991940.011
cell part morphogenesisGO:00329901230.011
negative regulation of protein metabolic processGO:00512481140.011
organonitrogen compound catabolic processGO:19015651790.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of neuron apoptotic processGO:0043523830.011
regulation of kinase activityGO:00435491170.011
positive regulation of camp metabolic processGO:0030816310.011
regulation of phosphorylationGO:00423252480.011
purine ribonucleoside metabolic processGO:00461281680.011
bmp signaling pathwayGO:003050940.011
chromosome segregationGO:000705920.011
positive regulation of cyclic nucleotide metabolic processGO:0030801370.011
response to oxidative stressGO:00069791860.011
regulation of cytoskeleton organizationGO:0051493490.011
protein transportGO:00150311320.011
regulation of cell migrationGO:00303341280.011
calcium ion homeostasisGO:00550741620.011
ion homeostasisGO:00508012120.011
regulation of immune system processGO:00026821230.011
regulation of intracellular signal transductionGO:19025312180.011
hormone transportGO:00099141210.010
regulation of protein phosphorylationGO:00019321830.010
negative regulation of nitrogen compound metabolic processGO:00511721610.010
regulation of system processGO:00440572080.010
axonogenesisGO:0007409710.010
positive regulation of cell motilityGO:2000147970.010
male mating behaviorGO:006017930.010
regulation of peptidase activityGO:0052547550.010
positive regulation of cellular component organizationGO:00511302000.010
positive regulation of programmed cell deathGO:00430681570.010
negative regulation of developmental processGO:00510931250.010
regulation of cyclic nucleotide biosynthetic processGO:0030802450.010
nucleoside phosphate biosynthetic processGO:19012931020.010

Map4k5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
musculoskeletal system diseaseDOID:1700.012
organ system cancerDOID:005068600.010