Rattus norvegicus

230 known processes

Rapgef2

Rap guanine nucleotide exchange factor (GEF) 2

Rapgef2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of intracellular signal transductionGO:19025312180.131
positive regulation of multicellular organismal processGO:00512403870.126
regulation of signal transductionGO:00099663180.122
regulation of cellular component organizationGO:00511283680.094
learning or memoryGO:0007611900.090
neurological system processGO:00508772190.080
positive regulation of developmental processGO:00510942830.079
central nervous system developmentGO:00074173110.079
regulation of locomotionGO:00400121480.078
Rat
brain developmentGO:00074202470.078
behaviorGO:00076102050.076
positive regulation of cell differentiationGO:00455972170.073
programmed cell deathGO:00125013920.069
Human
regulation of programmed cell deathGO:00430673410.065
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353190.064
regulation of cell developmentGO:00602842630.062
positive regulation of response to stimulusGO:00485842850.060
head developmentGO:00603222470.060
amine metabolic processGO:0009308380.058
cell projection organizationGO:00300303020.057
regulation of transcription from rna polymerase ii promoterGO:00063572340.056
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.055
single organism behaviorGO:00447081300.055
intracellular signal transductionGO:00355563140.051
regulation of transcription dna templatedGO:00063553740.050
vesicle mediated transportGO:00161921810.048
secretion by cellGO:00329402480.048
nucleoside phosphate metabolic processGO:00067532830.048
phosphatidylinositol dephosphorylationGO:004685640.047
cellular ion homeostasisGO:00068731840.047
single organism intracellular transportGO:19025821660.047
protein import into nucleusGO:0006606350.045
positive regulation of gene expressionGO:00106282440.044
response to metal ionGO:00100382530.043
positive regulation of biosynthetic processGO:00098913190.043
nucleic acid templated transcriptionGO:00976593790.043
regulation of apoptotic processGO:00429813350.043
Human
negative regulation of signalingGO:00230571570.042
Rat
regulation of protein metabolic processGO:00512462890.042
regulation of nervous system developmentGO:00519602640.042
divalent metal ion transportGO:00708381320.042
response to cytokineGO:00340972150.041
forebrain developmentGO:0030900980.040
oxoacid metabolic processGO:00434362900.040
cellular response to stressGO:00335542690.040
positive regulation of signalingGO:00230562700.040
regulation of multicellular organismal developmentGO:20000263760.040
cellular chemical homeostasisGO:00550822470.039
positive regulation of cytosolic calcium ion concentrationGO:00072041220.039
adult locomotory behaviorGO:000834440.039
response to carbohydrateGO:00097431830.039
positive regulation of cellular biosynthetic processGO:00313282950.038
positive regulation of nitrogen compound metabolic processGO:00511733340.038
cellular component morphogenesisGO:00329891550.038
Human
cellular protein localizationGO:00346131220.038
cellular lipid metabolic processGO:00442552080.037
divalent inorganic cation homeostasisGO:00725071650.037
reproductive processGO:00224143720.037
secretionGO:00469033070.037
carboxylic acid metabolic processGO:00197522890.036
cellular response to oxygen containing compoundGO:19017013860.036
Human
ion homeostasisGO:00508012120.036
cellular divalent inorganic cation homeostasisGO:00725031620.036
regulation of phosphorylationGO:00423252480.035
transcription dna templatedGO:00063513770.035
organic acid metabolic processGO:00060822920.034
positive regulation of endocytosisGO:0045807280.034
catabolic processGO:00090563510.034
cellular calcium ion homeostasisGO:00068741600.033
regulation of molecular functionGO:00650093980.033
nitrogen compound transportGO:00717052290.032
dephosphorylationGO:0016311980.032
cation homeostasisGO:00550801950.032
cellular catabolic processGO:00442482950.032
single organism cellular localizationGO:19025801020.032
cellular component movementGO:00069282480.032
Rat
response to acid chemicalGO:00011012220.032
organophosphate metabolic processGO:00196373700.032
rna metabolic processGO:00160704060.031
cellular amine metabolic processGO:0044106380.031
regulation of cellular amine metabolic processGO:003323880.031
memoryGO:0007613540.030
ribonucleotide metabolic processGO:00092592310.030
cognitionGO:0050890920.030
single organism biosynthetic processGO:00447113420.030
negative regulation of transportGO:00510511360.030
regulation of phosphorus metabolic processGO:00511743490.030
enzyme linked receptor protein signaling pathwayGO:00071671160.030
cellular homeostasisGO:00197252520.029
cellular response to growth factor stimulusGO:00713631620.029
regulation of cellular ketone metabolic processGO:0010565270.029
locomotionGO:00400112370.029
Rat
calcium ion homeostasisGO:00550741620.028
homeostatic processGO:00425923310.028
response to oxygen levelsGO:00704822650.028
cellular cation homeostasisGO:00300031800.028
response to extracellular stimulusGO:00099913800.028
organophosphate catabolic processGO:00464341480.028
regulation of nucleic acid templated transcriptionGO:19035063800.028
negative regulation of cell communicationGO:00106481580.028
Rat
regulation of neuron deathGO:19012141150.028
positive regulation of neurogenesisGO:00507691650.028
purine containing compound metabolic processGO:00725212530.027
limbic system developmentGO:0021761380.027
positive regulation of nervous system developmentGO:00519621780.027
cellular response to endogenous stimulusGO:00714953770.027
regulation of rna metabolic processGO:00512523910.027
response to calcium ionGO:0051592590.027
protein modification by small protein conjugationGO:0032446310.027
cation transportGO:00068123820.027
neuron developmentGO:00486662860.027
multicellular organism growthGO:003526410.027
response to nutrient levelsGO:00316673700.026
positive regulation of transportGO:00510502450.026
regulation of protein phosphorylationGO:00019321830.026
insulin like growth factor receptor signaling pathwayGO:004800930.026
positive regulation of phosphate metabolic processGO:00459372620.026
glycosyl compound catabolic processGO:19016581260.026
negative regulation of cell deathGO:00605482290.026
transmembrane transportGO:00550854120.026
tissue developmentGO:00098882520.026
Human
negative regulation of apoptotic processGO:00430661810.026
inorganic cation transmembrane transportGO:00986622020.025
regulation of cellular amino acid metabolic processGO:000652120.025
positive regulation of cell developmentGO:00107201760.025
rhythmic processGO:00485111560.025
apoptotic processGO:00069153810.025
Human
single organism nuclear importGO:1902593350.025
regulation of cellular protein metabolic processGO:00322682670.025
membrane organizationGO:0061024940.024
response to interleukin 15GO:007067240.024
positive regulation of cellular amine metabolic processGO:003324030.024
metal ion homeostasisGO:00550651860.024
regulation of secretion by cellGO:19035302080.024
lipid metabolic processGO:00066292830.024
response to peptide hormoneGO:00434342780.024
positive regulation of rna biosynthetic processGO:19026801970.024
learningGO:0007612330.024
cytosolic calcium ion homeostasisGO:00514801400.024
rna biosynthetic processGO:00327743800.023
response to inorganic substanceGO:00100353770.023
cellular component assemblyGO:00226073600.023
Human
purine ribonucleotide metabolic processGO:00091502270.023
cellular response to hormone stimulusGO:00328702470.023
receptor mediated endocytosisGO:0006898420.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
proteolysisGO:00065081750.022
positive regulation of growthGO:0045927550.022
divalent inorganic cation transportGO:00725111340.022
muscle structure developmentGO:0061061870.022
calcium ion transportGO:00068161310.022
positive regulation of neuron differentiationGO:00456661260.022
carbohydrate derivative metabolic processGO:19011353460.022
single organism catabolic processGO:00447122830.021
inorganic ion transmembrane transportGO:00986602290.021
aromatic compound catabolic processGO:00194391680.021
positive regulation of signal transductionGO:00099671750.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
cellular amino acid metabolic processGO:00065201070.021
nucleobase containing small molecule metabolic processGO:00550863160.021
regulation of membrane potentialGO:00423911100.020
cell part morphogenesisGO:00329901230.020
Human
regulation of vesicle mediated transportGO:0060627810.020
cellular response to cytokine stimulusGO:00713451270.020
cell cell signalingGO:00072673350.020
positive regulation of cellular component organizationGO:00511302000.020
positive regulation of cell projection organizationGO:00313461110.020
regulation of rna biosynthetic processGO:20011413810.020
positive regulation of rna metabolic processGO:00512542030.020
action potentialGO:0001508540.020
carbohydrate derivative biosynthetic processGO:19011371240.020
positive regulation of molecular functionGO:00440932300.020
cellular response to interleukin 15GO:007135030.020
neuron differentiationGO:00301823680.020
purine nucleotide metabolic processGO:00061632290.020
alcohol metabolic processGO:0006066770.020
organelle organizationGO:00069962660.020
purine containing compound catabolic processGO:00725231380.020
transmission of nerve impulseGO:0019226420.020
response to reactive oxygen speciesGO:00003021200.019
protein transportGO:00150311320.019
negative regulation of programmed cell deathGO:00430691830.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
ras protein signal transductionGO:0007265290.019
Human
glycosyl compound metabolic processGO:19016571820.019
nucleobase containing compound catabolic processGO:00346551520.019
positive regulation of protein metabolic processGO:00512471780.019
negative regulation of response to stimulusGO:00485851550.019
positive regulation of locomotionGO:00400171020.019
Rat
regulation of homeostatic processGO:00328441010.019
chemical homeostasisGO:00488782920.019
interleukin 12 productionGO:003261530.019
protein complex subunit organizationGO:00718223020.019
macromolecular complex subunit organizationGO:00439333390.019
striated muscle tissue developmentGO:0014706580.018
positive regulation of calcium ion dependent exocytosisGO:004595660.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
synapse organizationGO:0050808460.018
cellular ketone metabolic processGO:0042180510.018
positive regulation of hormone secretionGO:0046887650.018
cellular response to extracellular stimulusGO:0031668730.018
telencephalon developmentGO:0021537620.018
regulation of cell morphogenesisGO:0022604770.018
Human
neuronal action potentialGO:0019228350.018
response to growth factorGO:00708481890.017
motor neuron axon guidanceGO:000804510.017
regulation of canonical wnt signaling pathwayGO:006082840.017
ion transmembrane transportGO:00342203650.017
response to estrogenGO:00436272320.017
cellular protein complex assemblyGO:0043623440.017
multicellular organismal signalingGO:0035637440.017
negative regulation of signal transductionGO:0009968830.017
regulation of purine nucleotide metabolic processGO:19005421150.017
muscle tissue developmentGO:0060537580.017
cellular response to external stimulusGO:00714961180.017
axon guidanceGO:0007411240.017
cation transmembrane transportGO:00986552630.017
regulation of cellular component movementGO:00512701500.017
Rat
response to bacteriumGO:00096172000.017
growthGO:00400071650.017
positive regulation of neuron projection developmentGO:0010976990.016
developmental growthGO:00485891000.016
intracellular protein transportGO:0006886790.016
negative regulation of macromolecule metabolic processGO:00106052600.016
cellular response to organic cyclic compoundGO:00714072020.016
Human
signal releaseGO:00230611450.016
regulation of cellular extravasationGO:000269120.016
carbohydrate homeostasisGO:0033500750.016
organic substance catabolic processGO:19015753160.016
arp2 3 complex mediated actin nucleationGO:003431420.016
regulation of transferase activityGO:00513381230.016
protein complex assemblyGO:00064612630.015
response to glucoseGO:00097491360.015
regulation of protein modification processGO:00313991940.015
multi organism reproductive processGO:00447032620.015
positive regulation of hydrolase activityGO:0051345860.015
response to hydrogen peroxideGO:0042542890.015
synaptic transmissionGO:00072682350.015
regulation of peptide transportGO:0090087870.015
single organism organelle organizationGO:19025891800.015
pallium developmentGO:0021543420.015
response to external biotic stimulusGO:00432072210.015
protein ubiquitinationGO:0016567280.015
response to decreased oxygen levelsGO:00362932370.015
cytokine mediated signaling pathwayGO:0019221430.015
response to oxidative stressGO:00069791860.015
cellular macromolecule localizationGO:00707271220.015
purine ribonucleotide catabolic processGO:00091541360.015
taxisGO:0042330670.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
regulation of ion transportGO:00432692450.014
heterocycle catabolic processGO:00467001670.014
positive regulation of cellular protein metabolic processGO:00322701670.014
regulation of protein kinase a signalingGO:001073860.014
multi multicellular organism processGO:00447061380.014
response to ketoneGO:19016541820.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
organic hydroxy compound metabolic processGO:19016151150.014
regulation of anatomical structure sizeGO:00900661350.014
anterior posterior pattern specificationGO:000995210.014
cellular component biogenesisGO:00440853680.014
Human
macromolecular complex assemblyGO:00650032730.014
circulatory system developmentGO:00723591340.014
Rat
regenerationGO:00310991630.014
female pregnancyGO:00075651220.014
protein localizationGO:00081041910.014
regulation of immune system processGO:00026821230.014
response to hypoxiaGO:00016662310.014
glutamate receptor signaling pathwayGO:0007215430.014
regulation of cell cycleGO:0051726730.013
glycerophospholipid metabolic processGO:0006650470.013
regulation of neurogenesisGO:00507672470.013
muscle organ developmentGO:0007517500.013
protein complex biogenesisGO:00702712630.013
polyol metabolic processGO:0019751200.013
cell growthGO:00160491040.013
establishment of vesicle localizationGO:0051650310.013
regulation of cell motilityGO:20001451310.013
Rat
regulation of cell differentiationGO:00455953200.013
small molecule biosynthetic processGO:00442831240.013
g protein coupled acetylcholine receptor signaling pathwayGO:000721350.013
response to interleukin 1GO:0070555550.013
macromolecule localizationGO:00330362520.013
positive regulation of transcription dna templatedGO:00458931970.013
negative regulation of neuron deathGO:1901215690.013
ribonucleoside catabolic processGO:00424541260.013
cellular response to nitrogen compoundGO:19016992100.013
Human
positive regulation of cellular component movementGO:00512721020.013
Rat
muscle cell differentiationGO:0042692520.013
response to corticosteroidGO:00319602350.013
nucleoside phosphate catabolic processGO:19012921400.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.013
organonitrogen compound catabolic processGO:19015651790.013
negative regulation of cellular metabolic processGO:00313242810.013
establishment of protein localizationGO:00451841410.013
regulation of neuron apoptotic processGO:0043523830.013
organophosphate biosynthetic processGO:00904071430.012
cellular response to oxidative stressGO:0034599760.012
calcineurin nfat signaling cascadeGO:003317330.012
regulation of hormone secretionGO:00468831060.012
response to hexoseGO:00097461440.012
nucleotide metabolic processGO:00091172790.012
regulation of response to stressGO:00801341260.012
nucleotide catabolic processGO:00091661390.012
calcium ion transmembrane transportGO:0070588700.012
regulation of leukocyte migrationGO:0002685240.012
positive regulation of epithelial cell migrationGO:0010634130.012
response to glucocorticoidGO:00513842230.012
regulation of calcium ion transportGO:0051924770.012
synaptic vesicle primingGO:001608240.012
regulation of hormone levelsGO:00108171870.012
intracellular transportGO:00469071850.012
reproductionGO:00000032450.012
negative regulation of secretionGO:0051048820.012
fertilizationGO:000956630.012
neuron projection developmentGO:00311752730.012
negative regulation of secretion by cellGO:1903531720.012
cellular nitrogen compound catabolic processGO:00442701630.012
actin cytoskeleton organizationGO:0030036730.012
glycerolipid metabolic processGO:0046486670.012
sequestering of calcium ionGO:005120880.011
regulation of glycoprotein biosynthetic processGO:001055960.011
neurotrophin trk receptor signaling pathwayGO:0048011100.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
skeletal muscle tissue developmentGO:0007519310.011
regulation of phosphate metabolic processGO:00192203490.011
regulation of growthGO:00400081050.011
positive regulation of cell migrationGO:0030335960.011
Rat
glucose homeostasisGO:0042593750.011
muscle system processGO:00030121150.011
anion transportGO:00068201780.011
regulation of endocytosisGO:0030100420.011
regulation of cell proliferationGO:00421273590.011
Human
response to ethanolGO:00454711620.011
purine ribonucleoside metabolic processGO:00461281680.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
negative regulation of gene expressionGO:00106291990.011
endocytosisGO:0006897840.011
cell projection morphogenesisGO:00488581230.011
Human
regulation of protein targetingGO:1903533280.011
nucleoside triphosphate catabolic processGO:00091431230.011
positive regulation of cell communicationGO:00106472710.011
protein phosphorylationGO:00064683450.011
metal ion transportGO:00300012890.011
positive regulation of catalytic activityGO:00430851840.011
response to nutrientGO:00075842480.011
neuron projection morphogenesisGO:00488121220.011
Human
regulation of cellular component biogenesisGO:0044087860.011
Human
neuron apoptotic processGO:0051402880.011
axonogenesisGO:0007409710.011
regulation of cell growthGO:0001558850.011
cellular response to monosaccharide stimulusGO:0071326670.011
ribonucleoside metabolic processGO:00091191740.011
positive regulation of cell deathGO:00109421840.011
Human
regulation of kinase activityGO:00435491170.011
regulation of catalytic activityGO:00507903040.011
negative regulation of cellular component organizationGO:0051129830.010
Human
interleukin 1 mediated signaling pathwayGO:007049820.010
cell morphogenesis involved in differentiationGO:00009041190.010
Human
positive regulation of apoptotic processGO:00430651540.010
Human
single fertilizationGO:000733830.010
innate immune responseGO:0045087350.010
response to other organismGO:00517072200.010
ribose phosphate metabolic processGO:00196932350.010
organic cyclic compound catabolic processGO:19013611750.010
phospholipid metabolic processGO:0006644610.010
agingGO:00075682410.010
cell type specific apoptotic processGO:00972851340.010
Human
peptide secretionGO:0002790860.010
protein oligomerizationGO:00512591910.010
organic hydroxy compound biosynthetic processGO:1901617510.010
monovalent inorganic cation transportGO:00156721720.010
regulation of cellular localizationGO:00603412630.010
positive regulation of amine transportGO:0051954260.010
cell morphogenesisGO:00009021420.010
Human
gland developmentGO:00487321550.010
regulation of peptide hormone secretionGO:0090276800.010
regulation of mitotic sister chromatid separationGO:001096510.010
peptide transportGO:0015833970.010
negative regulation of viral processGO:004852540.010

Rapgef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.145
disease of anatomical entityDOID:700.145
central nervous system diseaseDOID:33100.120
brain diseaseDOID:93600.120
epilepsy syndromeDOID:182600.046
electroclinical syndromeDOID:005070100.030
parkinson s diseaseDOID:1433000.014
neurodegenerative diseaseDOID:128900.014
synucleinopathyDOID:005089000.014
neonatal period electroclinical syndromeDOID:005070200.010
ohtahara syndromeDOID:005070900.010