Rattus norvegicus

192 known processes

Serpinf1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

(Aliases: Pedf,Dmrs91)

Serpinf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue developmentGO:00098882520.249
homeostatic processGO:00425923310.153
apoptotic processGO:00069153810.140
cellular lipid metabolic processGO:00442552080.137
lipid metabolic processGO:00066292830.116
regulation of programmed cell deathGO:00430673410.107
cellular response to hormone stimulusGO:00328702470.087
bmp signaling pathwayGO:003050940.086
reproductive processGO:00224143720.085
oxoacid metabolic processGO:00434362900.080
hormone metabolic processGO:0042445690.080
cellular response to endogenous stimulusGO:00714953770.079
cardiovascular system developmentGO:00723581340.078
Human
programmed cell deathGO:00125013920.070
response to peptide hormoneGO:00434342780.065
response to glucocorticoidGO:00513842230.064
circulatory system developmentGO:00723591340.064
Human
cellular catabolic processGO:00442482950.063
regenerationGO:00310991630.063
regulation of apoptotic processGO:00429813350.062
negative regulation of cell deathGO:00605482290.061
developmental growthGO:00485891000.058
regulation of hormone levelsGO:00108171870.056
regulation of fat cell differentiationGO:004559830.055
positive regulation of multicellular organismal processGO:00512403870.055
positive regulation of developmental processGO:00510942830.054
cell growthGO:00160491040.054
response to oxygen levelsGO:00704822650.053
response to corticosteroidGO:00319602350.053
multi multicellular organism processGO:00447061380.052
positive regulation of transportGO:00510502450.052
response to extracellular stimulusGO:00099913800.052
growthGO:00400071650.050
response to peptideGO:19016522920.050
chemical homeostasisGO:00488782920.050
regulation of cell proliferationGO:00421273590.049
heart morphogenesisGO:000300730.048
regulation of multicellular organismal developmentGO:20000263760.048
positive regulation of cell proliferationGO:00082842490.048
response to fluorideGO:190261730.047
cellular response to peptide hormone stimulusGO:00713751200.046
positive regulation of cell deathGO:00109421840.045
organ morphogenesisGO:0009887750.045
monosaccharide metabolic processGO:0005996610.045
cellular amino acid metabolic processGO:00065201070.044
response to toxic substanceGO:00096361330.043
negative regulation of programmed cell deathGO:00430691830.042
response to nutrient levelsGO:00316673700.042
vasculature developmentGO:0001944700.042
Human
positive regulation of apoptotic processGO:00430651540.042
macromolecule localizationGO:00330362520.042
rna biosynthetic processGO:00327743800.042
regulation of nervous system developmentGO:00519602640.040
response to inorganic substanceGO:00100353770.040
negative regulation of multicellular organismal processGO:00512412030.039
regulation of neuron deathGO:19012141150.039
multi organism reproductive processGO:00447032620.039
carbohydrate derivative metabolic processGO:19011353460.038
catabolic processGO:00090563510.037
cellular response to organic cyclic compoundGO:00714072020.037
regulation of cell motilityGO:20001451310.037
cellular component assemblyGO:00226073600.036
protein oligomerizationGO:00512591910.036
positive regulation of secretionGO:00510471400.036
secretionGO:00469033070.036
behaviorGO:00076102050.035
regulation of cellular component organizationGO:00511283680.035
cellular amine metabolic processGO:0044106380.035
organic acid metabolic processGO:00060822920.035
ossificationGO:0001503700.035
liver developmentGO:0001889900.034
metal ion transportGO:00300012890.034
response to biotic stimulusGO:00096072260.034
regulation of anatomical structure morphogenesisGO:00226031410.034
Human
cell type specific apoptotic processGO:00972851340.033
positive regulation of cell communicationGO:00106472710.033
transcription dna templatedGO:00063513770.033
cellular modified amino acid metabolic processGO:0006575610.033
negative regulation of apoptotic processGO:00430661810.033
response to alkaloidGO:00432791320.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
inflammatory responseGO:00069541500.032
signal transduction by phosphorylationGO:00230141440.032
single organism catabolic processGO:00447122830.031
carbohydrate metabolic processGO:00059751300.031
response to radiationGO:00093141370.031
intracellular signal transductionGO:00355563140.031
multicellular organismal reproductive processGO:00486092330.031
positive regulation of programmed cell deathGO:00430681570.031
amine metabolic processGO:0009308380.030
response to estrogenGO:00436272320.030
wound healingGO:00420601220.029
Rat
regulation of rna metabolic processGO:00512523910.029
rna metabolic processGO:00160704060.029
response to molecule of bacterial originGO:00022371940.029
multicellular organism reproductionGO:00325042330.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.029
isoprenoid metabolic processGO:0006720450.029
terpenoid metabolic processGO:0006721370.029
gland developmentGO:00487321550.029
organonitrogen compound biosynthetic processGO:19015661670.028
jak stat cascadeGO:0007259260.028
response to estradiolGO:00323551640.028
nucleobase containing small molecule metabolic processGO:00550863160.028
regulation of growthGO:00400081050.028
small gtpase mediated signal transductionGO:0007264360.027
cellular response to growth factor stimulusGO:00713631620.027
reproductionGO:00000032450.027
positive regulation of biosynthetic processGO:00098913190.027
regulation of cell developmentGO:00602842630.027
proteolysisGO:00065081750.026
Rat
regulation of response to external stimulusGO:00321011060.026
response to acid chemicalGO:00011012220.026
response to ethanolGO:00454711620.025
carboxylic acid catabolic processGO:0046395490.025
cell migrationGO:00164771970.025
positive regulation of nervous system developmentGO:00519621780.025
response to insulinGO:00328681330.025
cellular amino acid biosynthetic processGO:0008652320.025
response to external biotic stimulusGO:00432072210.025
immune system processGO:00023762040.025
response to other organismGO:00517072200.024
transmembrane transportGO:00550854120.024
regulation of signal transductionGO:00099663180.024
secretion by cellGO:00329402480.024
calcium ion transportGO:00068161310.024
response to lipopolysaccharideGO:00324961910.024
cellular hormone metabolic processGO:0034754490.024
response to hypoxiaGO:00016662310.024
cellular response to stressGO:00335542690.023
response to dexamethasoneGO:0071548490.023
regulation of cell differentiationGO:00455953200.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
blood circulationGO:00080151830.023
female pregnancyGO:00075651220.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
angiogenesisGO:0001525530.022
Human
cellular response to mechanical stimulusGO:0071260480.022
multicellular organism growthGO:003526410.022
response to decreased oxygen levelsGO:00362932370.022
small molecule catabolic processGO:0044282590.022
regulation of ion transportGO:00432692450.022
protein complex biogenesisGO:00702712630.022
sexual reproductionGO:00199531480.022
cellular response to peptideGO:19016531330.021
prostate gland epithelium morphogenesisGO:006074020.021
immune responseGO:00069551040.021
cation transmembrane transportGO:00986552630.021
transcription from rna polymerase ii promoterGO:00063662520.021
cellular component biogenesisGO:00440853680.021
urogenital system developmentGO:0001655780.021
divalent inorganic cation transportGO:00725111340.021
positive regulation of cell projection organizationGO:00313461110.021
organic substance catabolic processGO:19015753160.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
positive regulation of macromolecule biosynthetic processGO:00105572470.021
organic hydroxy compound metabolic processGO:19016151150.021
protein complex assemblyGO:00064612630.020
cellular response to organonitrogen compoundGO:00714171970.020
response to glucoseGO:00097491360.020
neuron deathGO:00709971270.020
positive regulation of cell differentiationGO:00455972170.020
hexose metabolic processGO:0019318580.020
cellular biogenic amine metabolic processGO:0006576300.020
regulation of molecular functionGO:00650093980.020
Rat
ethanolamine containing compound metabolic processGO:0042439140.020
heterocycle catabolic processGO:00467001670.019
regulation of cell projection organizationGO:00313441750.019
prostate gland morphogenesisGO:006051220.019
macromolecular complex assemblyGO:00650032730.019
alcohol metabolic processGO:0006066770.019
single organism reproductive processGO:00447022970.019
divalent metal ion transportGO:00708381320.019
regulation of nucleic acid templated transcriptionGO:19035063800.019
gamete generationGO:00072761240.019
regulation of catalytic activityGO:00507903040.019
Rat
response to bacteriumGO:00096172000.019
connective tissue developmentGO:0061448330.019
response to activityGO:0014823730.019
agingGO:00075682410.018
sulfur compound metabolic processGO:0006790700.018
ras protein signal transductionGO:0007265290.018
regulation of secretionGO:00510462240.018
positive regulation of intracellular signal transductionGO:19025331380.018
eye morphogenesisGO:004859240.018
muscle structure developmentGO:0061061870.018
positive regulation of cellular biosynthetic processGO:00313282950.018
positive regulation of neuron differentiationGO:00456661260.017
negative regulation of cellular metabolic processGO:00313242810.017
Rat
regulation of neurogenesisGO:00507672470.017
regulation of secretion by cellGO:19035302080.017
positive regulation of catalytic activityGO:00430851840.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.017
anatomical structure morphogenesisGO:00096532980.017
Human
neuron differentiationGO:00301823680.017
cognitionGO:0050890920.017
regulation of cellular amine metabolic processGO:003323880.017
negative regulation of response to stimulusGO:00485851550.017
regulation of neuron projection developmentGO:00109751610.017
enzyme linked receptor protein signaling pathwayGO:00071671160.017
regulation of cell growthGO:0001558850.017
cellular response to nitrogen compoundGO:19016992100.017
cellular chemical homeostasisGO:00550822470.017
cofactor metabolic processGO:0051186950.017
regulation of bmp signaling pathwayGO:003051020.017
head developmentGO:00603222470.017
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.017
nucleoside phosphate metabolic processGO:00067532830.016
muscle tissue developmentGO:0060537580.016
cellular homeostasisGO:00197252520.016
ion transmembrane transportGO:00342203650.016
monocarboxylic acid transportGO:0015718520.016
formation of primary germ layerGO:000170410.016
negative regulation of biosynthetic processGO:00098901680.016
positive regulation of rna biosynthetic processGO:19026801970.016
positive regulation of molecular functionGO:00440932300.016
organonitrogen compound catabolic processGO:19015651790.016
positive regulation of fat cell differentiationGO:004560020.016
response to hexoseGO:00097461440.016
chromosome segregationGO:000705920.016
regulation of locomotionGO:00400121480.016
positive regulation of transcription dna templatedGO:00458931970.016
positive regulation of growthGO:0045927550.016
response to oxidative stressGO:00069791860.016
positive regulation of cellular component movementGO:00512721020.016
organic cyclic compound catabolic processGO:19013611750.016
cellular cation homeostasisGO:00300031800.016
defense responseGO:00069521940.016
macromolecular complex subunit organizationGO:00439333390.016
response to transforming growth factor betaGO:0071559460.015
renal system developmentGO:0072001670.015
negative regulation of gene expressionGO:00106291990.015
organophosphate metabolic processGO:00196373700.015
positive regulation of signalingGO:00230562700.015
development of primary sexual characteristicsGO:00451371070.015
circulatory system processGO:00030131830.015
spermatogenesisGO:0007283990.015
phospholipid metabolic processGO:0006644610.015
response to cytokineGO:00340972150.015
cellular component movementGO:00069282480.015
regulation of cellular ketone metabolic processGO:0010565270.015
positive regulation of cellular amine metabolic processGO:003324030.015
insulin like growth factor receptor signaling pathwayGO:004800930.015
protein localizationGO:00081041910.015
positive regulation of cellular component organizationGO:00511302000.015
cellular response to oxygen containing compoundGO:19017013860.015
nucleotide metabolic processGO:00091172790.015
retinal metabolic processGO:004257430.015
response to nutrientGO:00075842480.015
g protein coupled receptor signaling pathwayGO:00071862420.015
carbohydrate derivative biosynthetic processGO:19011371240.015
response to ketoneGO:19016541820.015
protein heterooligomerizationGO:0051291890.014
epithelial cell proliferationGO:0050673540.014
establishment of protein localizationGO:00451841410.014
negative regulation of cell communicationGO:00106481580.014
gonad developmentGO:00084061040.014
sulfur compound biosynthetic processGO:0044272190.014
anion transportGO:00068201780.014
nitrogen compound transportGO:00717052290.014
positive regulation of secretion by cellGO:19035321280.014
neuron developmentGO:00486662860.014
negative regulation of metabolic processGO:00098923310.014
glial cell differentiationGO:0010001650.014
lipid localizationGO:0010876620.014
single organism biosynthetic processGO:00447113420.014
positive regulation of neuron projection developmentGO:0010976990.014
central nervous system developmentGO:00074173110.014
single organism carbohydrate metabolic processGO:00447231180.014
protein complex subunit organizationGO:00718223020.014
regulation of synaptic transmissionGO:00508041410.014
positive regulation of gene expressionGO:00106282440.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
Human
positive regulation of ion transportGO:0043270940.014
response to starvationGO:0042594590.013
protein transportGO:00150311320.013
cellular component morphogenesisGO:00329891550.013
organic acid catabolic processGO:0016054490.013
carboxylic acid metabolic processGO:00197522890.013
embryonic skeletal system developmentGO:004870630.013
negative regulation of signalingGO:00230571570.013
cellular response to insulin stimulusGO:0032869810.013
lipid biosynthetic processGO:00086101280.013
purine nucleotide metabolic processGO:00061632290.013
purine containing compound metabolic processGO:00725212530.013
monocarboxylic acid metabolic processGO:00327871520.013
glycosyl compound metabolic processGO:19016571820.013
regulation of cellular localizationGO:00603412630.013
nucleic acid templated transcriptionGO:00976593790.013
protein homooligomerizationGO:0051260910.013
regulation of neuron differentiationGO:00456642080.013
response to reactive oxygen speciesGO:00003021200.013
negative regulation of macromolecule metabolic processGO:00106052600.012
glycosaminoglycan biosynthetic processGO:000602440.012
positive regulation of cell developmentGO:00107201760.012
regulation of intracellular signal transductionGO:19025312180.012
purine nucleoside metabolic processGO:00422781690.012
regulation of hydrolase activityGO:00513361430.012
Rat
positive regulation of immune system processGO:0002684900.012
regulation of transcription dna templatedGO:00063553740.012
regulation of jak stat cascadeGO:0046425210.012
cellular response to transforming growth factor beta stimulusGO:0071560410.012
response to monosaccharideGO:00342841590.012
glucose metabolic processGO:0006006520.012
cellular response to external stimulusGO:00714961180.012
vascular process in circulatory systemGO:0003018960.012
cellular response to alcoholGO:0097306870.012
cardiac chamber developmentGO:000320510.012
regulation of phosphate metabolic processGO:00192203490.012
rho protein signal transductionGO:0007266110.012
rhythmic processGO:00485111560.012
response to campGO:0051591910.012
cerebellar granule cell precursor proliferationGO:002193010.012
limb morphogenesisGO:003510840.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126910.012
tube developmentGO:0035295890.011
protein phosphorylationGO:00064683450.011
regulation of rna biosynthetic processGO:20011413810.011
cell proliferation in external granule layerGO:002192410.011
ribose phosphate metabolic processGO:00196932350.011
nucleoside metabolic processGO:00091161790.011
synaptic transmissionGO:00072682350.011
hepaticobiliary system developmentGO:0061008900.011
positive regulation of cytokine productionGO:0001819420.011
reproductive system developmentGO:00614581280.011
regulation of immunoglobulin secretionGO:005102310.011
cation transportGO:00068123820.011
adult locomotory behaviorGO:000834440.011
positive regulation of protein metabolic processGO:00512471780.011
organic acid biosynthetic processGO:0016053830.011
male gamete generationGO:0048232990.011
muscle cell proliferationGO:0033002840.011
learning or memoryGO:0007611900.011
axis specificationGO:000979840.011
regulation of cellular amino acid metabolic processGO:000652120.011
locomotionGO:00400112370.011
glycerolipid metabolic processGO:0046486670.011
organic acid transportGO:00158491160.011
organ growthGO:0035265240.011
regulation of phosphorus metabolic processGO:00511743490.011
positive regulation of hydrolase activityGO:0051345860.011
negative regulation of cellular biosynthetic processGO:00313271610.011
organ regenerationGO:00311001010.011
positive regulation of neurogenesisGO:00507691650.011
neuron apoptotic processGO:0051402880.011
organic anion transportGO:00157111320.010
cell cell signalingGO:00072673350.010
cellular response to corticosteroid stimulusGO:0071384690.010
regulation of response to stressGO:00801341260.010
negative regulation of neuron deathGO:1901215690.010
cellular response to hexose stimulusGO:0071331650.010
response to electrical stimulusGO:0051602560.010
cellular metal ion homeostasisGO:00068751720.010
regulation of cell migrationGO:00303341280.010
inorganic ion transmembrane transportGO:00986602290.010
glucose homeostasisGO:0042593750.010
organic hydroxy compound transportGO:0015850770.010
negative regulation of response to biotic stimulusGO:000283240.010
transmission of nerve impulseGO:0019226420.010
smooth muscle cell proliferationGO:0048659770.010
cellular response to abiotic stimulusGO:0071214850.010
cellular response to nutrient levelsGO:0031669600.010
multicellular organismal signalingGO:0035637440.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
response to organophosphorusGO:00466831020.010
organelle organizationGO:00069962660.010
mapk cascadeGO:00001651400.010
regulation of immune system processGO:00026821230.010
cellular response to extracellular stimulusGO:0031668730.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.010

Serpinf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.046
Human
disease of anatomical entityDOID:700.046
Human
connective tissue diseaseDOID:6500.046
Human
bone development diseaseDOID:008000600.039
Human
bone diseaseDOID:008000100.039
Human
disease of metabolismDOID:001466700.029
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.012
muscular diseaseDOID:008000000.011