Rattus norvegicus

153 known processes

Arhgef15

Rho guanine nucleotide exchange factor (GEF) 15

Arhgef15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell motilityGO:00488702020.193
circulatory system developmentGO:00723591340.155
positive regulation of nucleobase containing compound metabolic processGO:00459353190.145
angiogenesisGO:0001525530.141
blood vessel developmentGO:0001568690.132
vasculature developmentGO:0001944700.125
cardiovascular system developmentGO:00723581340.124
regulation of cellular component movementGO:00512701500.099
blood vessel morphogenesisGO:0048514580.096
reproductive processGO:00224143720.096
negative regulation of cell deathGO:00605482290.093
cell migrationGO:00164771970.087
cellular component movementGO:00069282480.085
intracellular signal transductionGO:00355563140.082
regulation of programmed cell deathGO:00430673410.082
organophosphate metabolic processGO:00196373700.079
response to extracellular stimulusGO:00099913800.078
positive regulation of biosynthetic processGO:00098913190.076
positive regulation of regulatory t cell differentiationGO:004559120.075
single organism reproductive processGO:00447022970.074
regulation of locomotionGO:00400121480.070
response to oxygen levelsGO:00704822650.068
regulation of multicellular organismal developmentGO:20000263760.067
negative regulation of multicellular organismal processGO:00512412030.066
regulation of cell proliferationGO:00421273590.064
positive regulation of multicellular organismal processGO:00512403870.063
response to hypoxiaGO:00016662310.062
oxoacid metabolic processGO:00434362900.062
single organism biosynthetic processGO:00447113420.062
multicellular organism reproductionGO:00325042330.061
circulatory system processGO:00030131830.061
response to nutrientGO:00075842480.060
response to decreased oxygen levelsGO:00362932370.060
single organism catabolic processGO:00447122830.059
defense responseGO:00069521940.059
reproductive system developmentGO:00614581280.057
negative regulation of cellular biosynthetic processGO:00313271610.056
transcription dna templatedGO:00063513770.056
nucleoside phosphate metabolic processGO:00067532830.056
anatomical structure morphogenesisGO:00096532980.055
purine nucleotide metabolic processGO:00061632290.055
programmed cell deathGO:00125013920.052
positive regulation of cellular component movementGO:00512721020.052
developmental process involved in reproductionGO:00030061590.052
localization of cellGO:00516742020.051
anatomical structure formation involved in morphogenesisGO:0048646830.051
blood circulationGO:00080151830.050
positive regulation of nitrogen compound metabolic processGO:00511733340.049
regulation of apoptotic processGO:00429813350.049
regulation of cell motilityGO:20001451310.048
response to purine containing compoundGO:00140741260.048
organic substance catabolic processGO:19015753160.048
positive regulation of cell differentiationGO:00455972170.048
response to organophosphorusGO:00466831020.048
positive regulation of cellular biosynthetic processGO:00313282950.047
regulation of signal transductionGO:00099663180.047
reproductive structure developmentGO:00486081280.047
metal ion homeostasisGO:00550651860.047
cellular component assemblyGO:00226073600.046
regulation of cell migrationGO:00303341280.046
response to nutrient levelsGO:00316673700.046
regulation of nucleic acid templated transcriptionGO:19035063800.045
nucleobase containing small molecule metabolic processGO:00550863160.045
regulation of catalytic activityGO:00507903040.044
positive regulation of phosphorus metabolic processGO:00105622620.043
regulation of intracellular signal transductionGO:19025312180.043
organ morphogenesisGO:0009887750.043
positive regulation of macromolecule biosynthetic processGO:00105572470.042
positive regulation of developmental processGO:00510942830.042
multicellular organismal reproductive processGO:00486092330.042
carbohydrate derivative metabolic processGO:19011353460.041
regulation of molecular functionGO:00650093980.041
cellular ion homeostasisGO:00068731840.041
negative regulation of metabolic processGO:00098923310.041
protein complex biogenesisGO:00702712630.041
response to inorganic substanceGO:00100353770.041
carboxylic acid metabolic processGO:00197522890.041
apoptotic processGO:00069153810.040
cellular amino acid metabolic processGO:00065201070.040
rna biosynthetic processGO:00327743800.040
muscle system processGO:00030121150.039
chemical homeostasisGO:00488782920.039
positive regulation of cell motilityGO:2000147970.039
ribose phosphate metabolic processGO:00196932350.039
positive regulation of transcription dna templatedGO:00458931970.038
nucleoside metabolic processGO:00091161790.038
macromolecular complex assemblyGO:00650032730.038
negative regulation of cellular metabolic processGO:00313242810.038
negative regulation of apoptotic processGO:00430661810.038
negative regulation of macromolecule metabolic processGO:00106052600.038
homeostatic processGO:00425923310.038
enzyme linked receptor protein signaling pathwayGO:00071671160.037
innate immune responseGO:0045087350.037
negative regulation of programmed cell deathGO:00430691830.037
cellular response to endogenous stimulusGO:00714953770.037
positive regulation of cell proliferationGO:00082842490.037
macromolecular complex subunit organizationGO:00439333390.036
transcription from rna polymerase ii promoterGO:00063662520.036
negative regulation of macromolecule biosynthetic processGO:00105581480.036
reproductionGO:00000032450.036
lipid metabolic processGO:00066292830.036
skeletal system developmentGO:0001501410.036
neurological system processGO:00508772190.036
reactive oxygen species biosynthetic processGO:190340980.036
catabolic processGO:00090563510.036
cellular component biogenesisGO:00440853680.035
tube developmentGO:0035295890.035
cellular metal ion homeostasisGO:00068751720.035
regulation of cell differentiationGO:00455953200.034
organic acid metabolic processGO:00060822920.034
tissue developmentGO:00098882520.034
positive regulation of gene expressionGO:00106282440.034
development of primary sexual characteristicsGO:00451371070.033
regulation of nucleotide metabolic processGO:00061401170.033
response to growth factorGO:00708481890.033
cellular homeostasisGO:00197252520.033
cellular response to hormone stimulusGO:00328702470.033
calcium ion homeostasisGO:00550741620.033
regulation of ion transportGO:00432692450.033
gland developmentGO:00487321550.033
behaviorGO:00076102050.032
regulation of phosphate metabolic processGO:00192203490.032
multi multicellular organism processGO:00447061380.032
regulation of canonical wnt signaling pathwayGO:006082840.032
locomotionGO:00400112370.032
female pregnancyGO:00075651220.031
multi organism reproductive processGO:00447032620.031
cellular response to lipidGO:00713962010.031
rhythmic processGO:00485111560.031
negative regulation of nucleic acid templated transcriptionGO:19035071170.031
cellular response to stressGO:00335542690.031
regulation of system processGO:00440572080.031
response to acid chemicalGO:00011012220.031
cellular amine metabolic processGO:0044106380.031
regulation of regulatory t cell differentiationGO:004558920.031
cytosolic calcium ion homeostasisGO:00514801400.030
organonitrogen compound biosynthetic processGO:19015661670.030
cell projection organizationGO:00300303020.030
cellular catabolic processGO:00442482950.030
positive regulation of response to stimulusGO:00485842850.030
protein complex subunit organizationGO:00718223020.030
cation homeostasisGO:00550801950.030
cellular cation homeostasisGO:00300031800.030
glycosyl compound metabolic processGO:19016571820.030
regulation of rna metabolic processGO:00512523910.030
gonad developmentGO:00084061040.030
response to vitaminGO:00332731310.029
positive regulation of locomotionGO:00400171020.029
positive regulation of nervous system developmentGO:00519621780.029
oxidation reduction processGO:00551143040.028
rna metabolic processGO:00160704060.028
small gtpase mediated signal transductionGO:0007264360.028
positive regulation of phosphate metabolic processGO:00459372620.028
regulation of neurogenesisGO:00507672470.028
ribonucleoside metabolic processGO:00091191740.028
cellular response to oxygen containing compoundGO:19017013860.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.027
reactive nitrogen species metabolic processGO:200105710.027
regulation of angiogenesisGO:0045765390.027
protein oligomerizationGO:00512591910.027
regulation of immunoglobulin mediated immune responseGO:000288920.027
brain developmentGO:00074202470.027
neuron deathGO:00709971270.027
cellular response to organic cyclic compoundGO:00714072020.027
organophosphate biosynthetic processGO:00904071430.026
purine containing compound metabolic processGO:00725212530.026
sex differentiationGO:00075481130.026
regulation of immune system processGO:00026821230.026
cellular chemical homeostasisGO:00550822470.026
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.026
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
positive regulation of purine nucleotide metabolic processGO:1900544910.025
regulation of catabolic processGO:00098941130.025
response to monosaccharideGO:00342841590.025
divalent inorganic cation transportGO:00725111340.025
response to peptideGO:19016522920.025
positive regulation of cell migrationGO:0030335960.025
central nervous system developmentGO:00074173110.025
macromolecule localizationGO:00330362520.025
ras protein signal transductionGO:0007265290.025
growthGO:00400071650.025
regulation of reactive oxygen species biosynthetic processGO:190342650.025
regulation of cellular protein metabolic processGO:00322682670.025
regulation of hydrolase activityGO:00513361430.025
vasculogenesisGO:000157030.025
response to mechanical stimulusGO:00096121340.024
positive regulation of cellular component organizationGO:00511302000.024
divalent inorganic cation homeostasisGO:00725071650.024
positive regulation of protein metabolic processGO:00512471780.024
negative regulation of biosynthetic processGO:00098901680.024
positive regulation of rna metabolic processGO:00512542030.024
muscle cell proliferationGO:0033002840.024
amine metabolic processGO:0009308380.024
regulation of phosphorus metabolic processGO:00511743490.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.024
regulation of anatomical structure sizeGO:00900661350.024
response to estrogenGO:00436272320.024
protein phosphorylationGO:00064683450.024
smooth muscle cell proliferationGO:0048659770.024
cellular response to growth factor stimulusGO:00713631620.024
regulation of purine nucleotide metabolic processGO:19005421150.024
response to cytokineGO:00340972150.024
negative regulation of cell proliferationGO:00082851190.024
regulation of transcription dna templatedGO:00063553740.024
regulation of anatomical structure morphogenesisGO:00226031410.024
g protein coupled receptor signaling pathwayGO:00071862420.024
regulation of nervous system developmentGO:00519602640.024
response to campGO:0051591910.023
positive regulation of signalingGO:00230562700.023
response to carbohydrateGO:00097431830.023
regulation of cellular catabolic processGO:00313291010.023
purine ribonucleotide metabolic processGO:00091502270.023
multicellular organism growthGO:003526410.023
nucleotide metabolic processGO:00091172790.023
single organism intracellular transportGO:19025821660.023
sexual reproductionGO:00199531480.023
positive regulation of nucleotide metabolic processGO:0045981910.023
cellular divalent inorganic cation homeostasisGO:00725031620.023
metal ion transportGO:00300012890.023
heterocycle catabolic processGO:00467001670.023
response to oxidative stressGO:00069791860.022
bmp signaling pathwayGO:003050940.022
regulation of cell developmentGO:00602842630.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
regulation of cellular amino acid metabolic processGO:000652120.022
protein localizationGO:00081041910.022
regulation of growthGO:00400081050.022
regulation of cellular component organizationGO:00511283680.022
cellular ketone metabolic processGO:0042180510.022
purine ribonucleoside metabolic processGO:00461281680.022
hair cell differentiationGO:003531520.022
positive regulation of neurogenesisGO:00507691650.022
nucleic acid templated transcriptionGO:00976593790.022
regulation of transcription regulatory region dna bindingGO:200067740.021
negative regulation of signalingGO:00230571570.021
reactive oxygen species metabolic processGO:0072593370.021
ribonucleotide metabolic processGO:00092592310.021
response to other organismGO:00517072200.021
vascular endothelial growth factor receptor signaling pathwayGO:004801080.021
immune system processGO:00023762040.021
regulation of membrane potentialGO:00423911100.021
noradrenergic neuron differentiationGO:000335710.021
nucleoside triphosphate catabolic processGO:00091431230.021
nucleoside catabolic processGO:00091641260.021
gastrulationGO:000736920.021
regulation of smooth muscle cell proliferationGO:0048660750.021
sensory organ developmentGO:0007423740.021
bone developmentGO:0060348250.021
single organism organelle organizationGO:19025891800.021
purine nucleoside triphosphate catabolic processGO:00091461220.020
negative regulation of rna biosynthetic processGO:19026791180.020
neuron projection developmentGO:00311752730.020
positive regulation of cytosolic calcium ion concentrationGO:00072041220.020
cellular calcium ion homeostasisGO:00068741600.020
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.020
positive regulation of intracellular signal transductionGO:19025331380.020
regulation of defense responseGO:0031347680.020
regulation of cellular amine metabolic processGO:003323880.020
regulation of cellular ketone metabolic processGO:0010565270.020
immunoglobulin mediated immune responseGO:001606440.020
protein complex assemblyGO:00064612630.020
response to peptide hormoneGO:00434342780.020
negative regulation of innate immune responseGO:004582440.020
negative regulation of developmental processGO:00510931250.020
negative regulation of molecular functionGO:00440921330.020
ion transmembrane transportGO:00342203650.020
neuron differentiationGO:00301823680.020
organonitrogen compound catabolic processGO:19015651790.020
regenerationGO:00310991630.020
positive regulation of rna biosynthetic processGO:19026801970.019
cellular lipid metabolic processGO:00442552080.019
negative regulation of gene expressionGO:00106291990.019
organic hydroxy compound metabolic processGO:19016151150.019
intracellular transportGO:00469071850.019
nucleoside triphosphate metabolic processGO:00091411440.019
organelle organizationGO:00069962660.019
regulation of rna biosynthetic processGO:20011413810.019
carbohydrate derivative catabolic processGO:19011361470.019
negative regulation of response to stimulusGO:00485851550.019
purine containing compound catabolic processGO:00725231380.019
organ regenerationGO:00311001010.019
negative regulation of rna metabolic processGO:00512531230.019
head developmentGO:00603222470.019
response to ketoneGO:19016541820.018
negative regulation of transportGO:00510511360.018
peptidyl amino acid modificationGO:00181931260.018
response to metal ionGO:00100382530.018
inflammatory responseGO:00069541500.018
regulation of reactive oxygen species metabolic processGO:2000377260.018
positive regulation of immune system processGO:0002684900.018
regulation of b cell mediated immunityGO:000271220.018
regulation of vasculature developmentGO:1901342440.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
cellular response to external stimulusGO:00714961180.018
developmental growthGO:00485891000.017
glycosyl compound catabolic processGO:19016581260.017
cell activationGO:0001775970.017
carbohydrate derivative biosynthetic processGO:19011371240.017
response to lipopolysaccharideGO:00324961910.017
positive regulation of cell communicationGO:00106472710.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
ossificationGO:0001503700.017
cellular nitrogen compound catabolic processGO:00442701630.017
kidney developmentGO:0001822670.017
positive regulation of endothelial cell migrationGO:001059540.017
positive regulation of catalytic activityGO:00430851840.017
positive regulation of immunoglobulin mediated immune responseGO:000289120.017
sensory perceptionGO:00076001010.017
response to biotic stimulusGO:00096072260.017
cellular response to cytokine stimulusGO:00713451270.017
negative regulation of transcription regulatory region dna bindingGO:200067820.017
gamete generationGO:00072761240.017
cyclic nucleotide metabolic processGO:0009187800.017
ion homeostasisGO:00508012120.017
regulation of neuron deathGO:19012141150.016
positive regulation of humoral immune responseGO:000292220.016
purine nucleotide catabolic processGO:00061951360.016
heart morphogenesisGO:000300730.016
nucleobase containing compound catabolic processGO:00346551520.016
cellular component morphogenesisGO:00329891550.016
regulation of rho gtpase activityGO:0032319170.016
muscle structure developmentGO:0061061870.016
renal system developmentGO:0072001670.015
negative regulation of growthGO:0045926370.015
positive regulation of alpha beta t cell activationGO:004663520.015
transmembrane transportGO:00550854120.015
positive regulation of signal transductionGO:00099671750.015
regulation of neuron differentiationGO:00456642080.015
positive regulation of cell developmentGO:00107201760.015
response to reactive oxygen speciesGO:00003021200.015
positive regulation of molecular functionGO:00440932300.015
cell adhesionGO:00071551100.015
myeloid leukocyte differentiationGO:0002573200.015
biological adhesionGO:00226101100.015
response to glucocorticoidGO:00513842230.015
cation transportGO:00068123820.015
positive regulation of angiogenesisGO:0045766280.015
positive regulation of neuron differentiationGO:00456661260.015
positive regulation of phosphorylationGO:00423271770.015
regulation of alpha beta t cell activationGO:004663420.015
purine ribonucleotide biosynthetic processGO:0009152810.015
response to radiationGO:00093141370.015
negative regulation of canonical wnt signaling pathwayGO:009009040.015
cytoplasmic transportGO:00164821150.015
positive regulation of phagocytosis engulfmentGO:006010040.015
cell cell signalingGO:00072673350.015
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.015
neuron developmentGO:00486662860.014
positive regulation of cell projection organizationGO:00313461110.014
cyclic nucleotide biosynthetic processGO:0009190630.014
organic cyclic compound catabolic processGO:19013611750.014
positive regulation of protein modification processGO:00314011420.014
response to hexoseGO:00097461440.014
vascular process in circulatory systemGO:0003018960.014
nucleotide biosynthetic processGO:0009165980.014
nucleoside phosphate biosynthetic processGO:19012931020.014
regulation of muscle system processGO:0090257790.014
purine nucleoside catabolic processGO:00061521240.014
leukocyte activationGO:0045321760.014
inner ear receptor cell differentiationGO:006011320.014
lipid catabolic processGO:0016042460.014
regulation of blood pressureGO:0008217830.014
cellular response to nitrogen compoundGO:19016992100.014
axis specificationGO:000979840.014
actin filament based processGO:0030029860.014
calcium ion transportGO:00068161310.014
male sex differentiationGO:0046661640.014
response to activityGO:0014823730.014
regulation of response to stressGO:00801341260.014
nucleotide catabolic processGO:00091661390.014
cell morphogenesis involved in differentiationGO:00009041190.014
guanosine containing compound metabolic processGO:1901068740.014
cell substrate adhesionGO:0031589290.014
digestive system developmentGO:0055123410.014
nucleoside phosphate catabolic processGO:19012921400.014
negative regulation of cell differentiationGO:0045596990.014
ribonucleoside catabolic processGO:00424541260.014
positive regulation of cellular amine metabolic processGO:003324030.014
regulation of protein phosphorylationGO:00019321830.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
heart contractionGO:0060047570.013
oligopeptide transportGO:000685740.013
purine ribonucleoside catabolic processGO:00461301240.013
regulation of cell projection organizationGO:00313441750.013
response to estradiolGO:00323551640.013
rho protein signal transductionGO:0007266110.013
membrane organizationGO:0061024940.013
regulation of homeostatic processGO:00328441010.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
agingGO:00075682410.013
protein homooligomerizationGO:0051260910.013
ribonucleotide biosynthetic processGO:0009260850.013
dna metabolic processGO:0006259960.013
single organism membrane organizationGO:0044802740.013
secretionGO:00469033070.013
ameboidal type cell migrationGO:0001667260.013
response to molecule of bacterial originGO:00022371940.013
purine nucleoside metabolic processGO:00422781690.013
cyclic purine nucleotide metabolic processGO:0052652620.013
positive regulation of cd4 positive alpha beta t cell activationGO:200051610.013
ribonucleotide catabolic processGO:00092611360.013
regulation of protein metabolic processGO:00512462890.013
purine nucleotide biosynthetic processGO:0006164830.013
purine containing compound biosynthetic processGO:0072522850.013
nitrogen compound transportGO:00717052290.013
alpha beta t cell differentiationGO:004663220.013
cellular protein localizationGO:00346131220.013
positive regulation of natural killer cell mediated immunityGO:000271720.013
regulation of cell growthGO:0001558850.013
cellular response to organonitrogen compoundGO:00714171970.012
positive regulation of ion transportGO:0043270940.012
immune responseGO:00069551040.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
development of primary male sexual characteristicsGO:0046546590.012
guanosine containing compound catabolic processGO:1901069710.012
positive regulation of b cell mediated immunityGO:000271420.012
regulation of epithelial cell proliferationGO:0050678490.012
regulation of protein modification processGO:00313991940.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
cell chemotaxisGO:0060326310.012
lipid storageGO:001991510.012
camp biosynthetic processGO:0006171470.012
embryo developmentGO:0009790490.012
mesoderm developmentGO:000749820.012
embryonic pattern specificationGO:000988010.012
salivary gland developmentGO:000743130.012
artery developmentGO:006084030.012
protein autophosphorylationGO:0046777660.012
cellular macromolecule localizationGO:00707271220.012
epithelium developmentGO:0060429960.012
regulation of transferase activityGO:00513381230.012
cell growthGO:00160491040.012
cell morphogenesisGO:00009021420.012
regulation of cd4 positive alpha beta t cell activationGO:200051410.011
circadian rhythmGO:0007623880.011
positive regulation of transportGO:00510502450.011
temperature homeostasisGO:0001659170.011
male gonad developmentGO:0008584590.011
divalent metal ion transportGO:00708381320.011
response to ammonium ionGO:0060359710.011
multicellular organismal homeostasisGO:0048871490.011
negative regulation of immune system processGO:0002683390.011
response to bacteriumGO:00096172000.011
negative regulation of cell communicationGO:00106481580.011
positive regulation of protein phosphorylationGO:00019341350.011
t cell homeostasisGO:004302920.011
phospholipid metabolic processGO:0006644610.011
lymphocyte homeostasisGO:000226020.011
regulation of blood circulationGO:19035221100.011
actin cytoskeleton organizationGO:0030036730.011
gtp catabolic processGO:0006184710.011
regulation of ras gtpase activityGO:0032318320.011
synaptic transmissionGO:00072682350.011
response to tumor necrosis factorGO:0034612560.011
anterior posterior pattern specificationGO:000995210.011
cellular response to abiotic stimulusGO:0071214850.011
regulation of phosphorylationGO:00423252480.011
ovulation cycleGO:0042698670.011
endochondral bone morphogenesisGO:006035070.011
hepaticobiliary system developmentGO:0061008900.011
proteolysisGO:00065081750.011
intracellular protein transportGO:0006886790.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
cellular response to alcoholGO:0097306870.011
regulation of phagocytosis engulfmentGO:006009940.011
taxisGO:0042330670.011
female gonad developmentGO:0008585530.011
positive regulation of nucleoside metabolic processGO:0045979550.011
formation of primary germ layerGO:000170410.011
response to external biotic stimulusGO:00432072210.011
positive regulation of programmed cell deathGO:00430681570.011
regulation of intracellular transportGO:0032386650.011
cation transmembrane transportGO:00986552630.011
negative regulation of transcription dna templatedGO:00458921160.011
eye morphogenesisGO:004859240.011
regulation of phosphatidylinositol 3 kinase signalingGO:0014066140.011
regulation of tube sizeGO:0035150890.011
regulation of fat cell differentiationGO:004559830.011
response to ionizing radiationGO:0010212590.011
cellular response to mechanical stimulusGO:0071260480.011
coronary vasculature morphogenesisGO:006097730.011
cd4 positive alpha beta t cell differentiationGO:004336710.011
positive regulation of homeostatic processGO:0032846490.011
cellular response to steroid hormone stimulusGO:0071383930.011

Arhgef15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
disease of metabolismDOID:001466700.016
hypertensionDOID:1076300.012
essential hypertensionDOID:1082500.012
cardiovascular system diseaseDOID:128700.012
vascular diseaseDOID:17800.012
artery diseaseDOID:005082800.012
musculoskeletal system diseaseDOID:1700.011
inherited metabolic disorderDOID:65500.011