| apoptotic process | GO:0006915 | 381 | 0.330 | |
| regulation of nitric oxide synthase activity | GO:0050999 | 8 | 0.199 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.189 | |
| organelle organization | GO:0006996 | 266 | 0.189 | |
| regulation of high voltage gated calcium channel activity | GO:1901841 | 3 | 0.166 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.158 | |
| divalent inorganic cation transport | GO:0072511 | 134 | 0.154 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.149 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.146 | |
| metal ion transport | GO:0030001 | 289 | 0.134 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.130 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.123 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.121 | |
| cellular component assembly | GO:0022607 | 360 | 0.120 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.111 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.106 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.102 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.089 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.086 | |
| mitochondrion organization | GO:0007005 | 35 | 0.085 | |
| single organism catabolic process | GO:0044712 | 283 | 0.084 | |
| transmembrane transport | GO:0055085 | 412 | 0.084 | |
| response to metal ion | GO:0010038 | 253 | 0.082 | |
| intracellular transport | GO:0046907 | 185 | 0.080 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.080 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.077 | |
| cation transport | GO:0006812 | 382 | 0.074 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.073 | |
| cellular response to stress | GO:0033554 | 269 | 0.073 | |
| regulation of molecular function | GO:0065009 | 398 | 0.072 | |
| positive regulation of nitric oxide synthase activity | GO:0051000 | 5 | 0.069 | |
| calcium ion transport | GO:0006816 | 131 | 0.069 | |
| cell cycle | GO:0007049 | 101 | 0.067 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.061 | |
| programmed cell death | GO:0012501 | 392 | 0.061 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.060 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.060 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.058 | |
| response to inorganic substance | GO:0010035 | 377 | 0.058 | |
| homeostatic process | GO:0042592 | 331 | 0.057 | |
| proteolysis | GO:0006508 | 175 | 0.057 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.056 | |
| response to hypoxia | GO:0001666 | 231 | 0.055 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.055 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.055 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.054 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.054 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.053 | |
| regulation of organelle organization | GO:0033043 | 80 | 0.051 | |
| rna metabolic process | GO:0016070 | 406 | 0.050 | |
| response to peptide | GO:1901652 | 292 | 0.048 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 3 | 0.047 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.047 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 140 | 0.046 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.046 | |
| single organism cellular localization | GO:1902580 | 102 | 0.045 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.045 | |
| regulation of transporter activity | GO:0032409 | 50 | 0.045 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.044 | |
| ribonucleotide biosynthetic process | GO:0009260 | 85 | 0.044 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.044 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.043 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.042 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.041 | |
| cellular homeostasis | GO:0019725 | 252 | 0.041 | |
| response to ethanol | GO:0045471 | 162 | 0.041 | |
| response to insulin | GO:0032868 | 133 | 0.040 | |
| regulation of ion transmembrane transport | GO:0034765 | 121 | 0.040 | |
| nucleotide biosynthetic process | GO:0009165 | 98 | 0.040 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.040 | |
| activation of adenylate cyclase activity | GO:0007190 | 7 | 0.040 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.039 | |
| catabolic process | GO:0009056 | 351 | 0.039 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.038 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.038 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.037 | |
| macromolecule catabolic process | GO:0009057 | 58 | 0.036 | |
| protein transport | GO:0015031 | 132 | 0.035 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.035 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.035 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.034 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.034 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 4 | 0.034 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.034 | |
| response to corticosteroid | GO:0031960 | 235 | 0.033 | |
| positive regulation of oxidoreductase activity | GO:0051353 | 7 | 0.033 | |
| neuron differentiation | GO:0030182 | 368 | 0.032 | |
| inorganic cation transmembrane transport | GO:0098662 | 202 | 0.031 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.031 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.031 | |
| positive regulation of monooxygenase activity | GO:0032770 | 5 | 0.031 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.031 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.030 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.030 | |
| actin filament based process | GO:0030029 | 86 | 0.030 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.030 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.030 | |
| dephosphorylation | GO:0016311 | 98 | 0.029 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.029 | |
| reproductive process | GO:0022414 | 372 | 0.029 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.029 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.029 | |
| monosaccharide metabolic process | GO:0005996 | 61 | 0.028 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.028 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.028 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.028 | |
| behavioral response to ethanol | GO:0048149 | 1 | 0.028 | |
| establishment of protein localization | GO:0045184 | 141 | 0.028 | |
| regulation of cyclase activity | GO:0031279 | 21 | 0.027 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.027 | |
| regulation of transmembrane transport | GO:0034762 | 122 | 0.027 | |
| secretion by cell | GO:0032940 | 248 | 0.027 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.027 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.027 | |
| cell redox homeostasis | GO:0045454 | 1 | 0.026 | |
| regulation of ryanodine sensitive calcium release channel activity | GO:0060314 | 5 | 0.026 | |
| response to nutrient levels | GO:0031667 | 370 | 0.026 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.026 | |
| positive regulation of lyase activity | GO:0051349 | 15 | 0.026 | |
| response to other organism | GO:0051707 | 220 | 0.025 | |
| cellular protein localization | GO:0034613 | 122 | 0.025 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.025 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.025 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.025 | |
| transcription dna templated | GO:0006351 | 377 | 0.025 | |
| ribonucleotide catabolic process | GO:0009261 | 136 | 0.025 | |
| mitochondrial calcium ion transport | GO:0006851 | 2 | 0.024 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.024 | |
| positive regulation of cyclase activity | GO:0031281 | 15 | 0.024 | |
| intracellular protein transport | GO:0006886 | 79 | 0.024 | |
| purine nucleoside catabolic process | GO:0006152 | 124 | 0.024 | |
| regulation of mitochondrion organization | GO:0010821 | 7 | 0.023 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.023 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.023 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.023 | |
| reproductive system development | GO:0061458 | 128 | 0.023 | |
| nucleotide catabolic process | GO:0009166 | 139 | 0.023 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.023 | |
| apoptotic mitochondrial changes | GO:0008637 | 10 | 0.023 | |
| positive regulation of transport | GO:0051050 | 245 | 0.023 | |
| calcium ion transmembrane transport | GO:0070588 | 70 | 0.022 | |
| central nervous system development | GO:0007417 | 311 | 0.022 | |
| immune system process | GO:0002376 | 204 | 0.022 | |
| secretion | GO:0046903 | 307 | 0.022 | |
| eye development | GO:0001654 | 50 | 0.022 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.022 | |
| behavior | GO:0007610 | 205 | 0.022 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.022 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.021 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.021 | |
| macromolecule localization | GO:0033036 | 252 | 0.021 | |
| apoptotic signaling pathway | GO:0097190 | 27 | 0.021 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 84 | 0.021 | |
| head development | GO:0060322 | 247 | 0.021 | |
| response to biotic stimulus | GO:0009607 | 226 | 0.020 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 120 | 0.020 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.020 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.020 | |
| protein localization | GO:0008104 | 191 | 0.020 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.020 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 119 | 0.020 | |
| purine ribonucleotide catabolic process | GO:0009154 | 136 | 0.020 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.020 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.020 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 48 | 0.019 | |
| histone methylation | GO:0016571 | 3 | 0.019 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.019 | |
| regulation of monooxygenase activity | GO:0032768 | 8 | 0.019 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.019 | |
| response to cytokine | GO:0034097 | 215 | 0.019 | |
| cellular response to external stimulus | GO:0071496 | 118 | 0.019 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 48 | 0.019 | |
| neuron development | GO:0048666 | 286 | 0.019 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.019 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.018 | |
| response to ketone | GO:1901654 | 182 | 0.018 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 56 | 0.018 | |
| protein heterooligomerization | GO:0051291 | 89 | 0.018 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 1 | 0.018 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.018 | |
| regulation of protein targeting | GO:1903533 | 28 | 0.018 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.018 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.018 | |
| regulation of metal ion transport | GO:0010959 | 118 | 0.017 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.017 | |
| sexual reproduction | GO:0019953 | 148 | 0.017 | |
| single organism organelle organization | GO:1902589 | 180 | 0.017 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.017 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.017 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.017 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.017 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.017 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.017 | |
| nucleoside catabolic process | GO:0009164 | 126 | 0.017 | |
| regulation of calcium ion transmembrane transport | GO:1903169 | 18 | 0.017 | |
| regulation of intracellular transport | GO:0032386 | 65 | 0.017 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.017 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.016 | |
| cellular catabolic process | GO:0044248 | 295 | 0.016 | |
| locomotion | GO:0040011 | 237 | 0.016 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.016 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.016 | |
| response to activity | GO:0014823 | 73 | 0.016 | |
| regulation of cation channel activity | GO:2001257 | 23 | 0.016 | |
| regulation of ion transport | GO:0043269 | 245 | 0.016 | |
| mitochondrial transport | GO:0006839 | 19 | 0.016 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 55 | 0.016 | |
| glycerolipid metabolic process | GO:0046486 | 67 | 0.016 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.016 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.016 | |
| regulation of lyase activity | GO:0051339 | 22 | 0.015 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.015 | |
| gamete generation | GO:0007276 | 124 | 0.015 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.015 | |
| camp metabolic process | GO:0046058 | 63 | 0.015 | |
| protein complex assembly | GO:0006461 | 263 | 0.015 | |
| protein phosphorylation | GO:0006468 | 345 | 0.015 | |
| response to mineralocorticoid | GO:0051385 | 49 | 0.015 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.015 | |
| regulation of adenylate cyclase activity | GO:0045761 | 18 | 0.015 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.015 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.015 | |
| response to oxidative stress | GO:0006979 | 186 | 0.015 | |
| cellular response to extracellular stimulus | GO:0031668 | 73 | 0.015 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.015 | |
| response to amine | GO:0014075 | 46 | 0.015 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.015 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.015 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.014 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.014 | |
| purine containing compound biosynthetic process | GO:0072522 | 85 | 0.014 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 102 | 0.014 | |
| single organism reproductive process | GO:0044702 | 297 | 0.014 | |
| phosphatidylinositol dephosphorylation | GO:0046856 | 4 | 0.014 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 122 | 0.014 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 84 | 0.014 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.014 | |
| negative regulation of developmental process | GO:0051093 | 125 | 0.014 | |
| regulation of protein localization | GO:0032880 | 81 | 0.014 | |
| regulation of growth | GO:0040008 | 105 | 0.014 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.014 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.013 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.013 | |
| brain development | GO:0007420 | 247 | 0.013 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 55 | 0.013 | |
| blood circulation | GO:0008015 | 183 | 0.013 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.013 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.013 | |
| regulation of immune system process | GO:0002682 | 123 | 0.013 | |
| regulation of locomotion | GO:0040012 | 148 | 0.013 | |
| cellular component movement | GO:0006928 | 248 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.013 | |
| cardiac muscle cell contraction | GO:0086003 | 10 | 0.013 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.013 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.013 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.013 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 122 | 0.013 | |
| regulation of transmembrane transporter activity | GO:0022898 | 49 | 0.012 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.012 | |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.012 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.012 | |
| regulation of calcium ion transmembrane transporter activity | GO:1901019 | 17 | 0.012 | |
| purine nucleotide biosynthetic process | GO:0006164 | 83 | 0.012 | |
| anterior posterior pattern specification | GO:0009952 | 1 | 0.012 | |
| cellular response to starvation | GO:0009267 | 27 | 0.012 | |
| synaptic transmission | GO:0007268 | 235 | 0.012 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 123 | 0.012 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.012 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 141 | 0.012 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.012 | |
| response to alkaloid | GO:0043279 | 132 | 0.012 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.011 | |
| autophagic cell death | GO:0048102 | 4 | 0.011 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.011 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.011 | |
| atp catabolic process | GO:0006200 | 54 | 0.011 | |
| monovalent inorganic cation transport | GO:0015672 | 172 | 0.011 | |
| defense response | GO:0006952 | 194 | 0.011 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.011 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 28 | 0.011 | |
| cell cycle phase transition | GO:0044770 | 21 | 0.011 | |
| endomembrane system organization | GO:0010256 | 48 | 0.011 | |
| hormone secretion | GO:0046879 | 115 | 0.011 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.011 | |
| chromosome organization | GO:0051276 | 36 | 0.011 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.011 | |
| organ formation | GO:0048645 | 3 | 0.011 | |
| nucleic acid transport | GO:0050657 | 3 | 0.010 | |
| regulation of cellular component biogenesis | GO:0044087 | 86 | 0.010 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.010 | |
| atp metabolic process | GO:0046034 | 72 | 0.010 | |
| positive regulation of cyclic nucleotide biosynthetic process | GO:0030804 | 34 | 0.010 | |
| negative regulation of growth | GO:0045926 | 37 | 0.010 | |
