IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

RT1-DOa

RT1 class II, locus DOa

(Aliases: H2-Oa)

RGD: 3477
Ensembl: ENSRNOG00000026762
Entrez: 24984
UniProtKB: Q6MGB0

Process Predictions
Disease Predictions

RT1-DOa biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cell cell signaling	GO:0007267	335	0.356
regulation of cell proliferation	GO:0042127	359	0.214
protein phosphorylation	GO:0006468	345	0.207
response to extracellular stimulus	GO:0009991	380	0.202
positive regulation of multicellular organismal process	GO:0051240	387	0.200
heart morphogenesis	GO:0003007	3	0.199
regulation of molecular function	GO:0065009	398	0.192
chemical homeostasis	GO:0048878	292	0.145
positive regulation of rna biosynthetic process	GO:1902680	197	0.140
mesoderm development	GO:0007498	2	0.134
neuron projection guidance	GO:0097485	24	0.131
axon guidance	GO:0007411	24	0.127
head development	GO:0060322	247	0.126
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.126
negative regulation of cell proliferation	GO:0008285	119	0.125
regulation of phosphorus metabolic process	GO:0051174	349	0.117
response to hexose	GO:0009746	144	0.110
regulation of rna biosynthetic process	GO:2001141	381	0.104
response to wounding	GO:0009611	254	0.101
organonitrogen compound biosynthetic process	GO:1901566	167	0.101
muscle system process	GO:0003012	115	0.099
regulation of rna metabolic process	GO:0051252	391	0.098
regulation of hormone secretion	GO:0046883	106	0.095
regulation of system process	GO:0044057	208	0.093
development of primary sexual characteristics	GO:0045137	107	0.091
positive regulation of phosphate metabolic process	GO:0045937	262	0.089
chemotaxis	GO:0006935	66	0.088
positive regulation of lipid kinase activity	GO:0090218	2	0.087
myelination	GO:0042552	39	0.087
positive regulation of cellular biosynthetic process	GO:0031328	295	0.084
phasic smooth muscle contraction	GO:0014821	3	0.082
regulation of amine transport	GO:0051952	54	0.080
response to peptide	GO:1901652	292	0.075
central nervous system development	GO:0007417	311	0.073
metal ion homeostasis	GO:0055065	186	0.072
embryonic skeletal system development	GO:0048706	3	0.071
positive regulation of phosphorus metabolic process	GO:0010562	262	0.070
rna biosynthetic process	GO:0032774	380	0.070
lymphoid progenitor cell differentiation	GO:0002320	2	0.069
positive regulation of phosphatidylinositol 3 kinase activity	GO:0043552	2	0.068
cellular response to oxygen containing compound	GO:1901701	386	0.067
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.066
muscle contraction	GO:0006936	88	0.066
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.065
rna metabolic process	GO:0016070	406	0.064
response to inorganic substance	GO:0010035	377	0.063
response to nutrient levels	GO:0031667	370	0.063
heart valve morphogenesis	GO:0003179	1	0.061
circadian rhythm	GO:0007623	88	0.061
learning or memory	GO:0007611	90	0.060
regulation of muscle system process	GO:0090257	79	0.060
cellular protein localization	GO:0034613	122	0.060
neurological system process	GO:0050877	219	0.059
response to alkaloid	GO:0043279	132	0.058
gonad development	GO:0008406	104	0.057
regulation of muscle contraction	GO:0006937	53	0.057
response to carbohydrate	GO:0009743	183	0.056
homeostatic process	GO:0042592	331	0.056
transcription from rna polymerase ii promoter	GO:0006366	252	0.056
response to retinoic acid	GO:0032526	63	0.055
purine ribonucleotide metabolic process	GO:0009150	227	0.053
axon development	GO:0061564	96	0.053
carbohydrate metabolic process	GO:0005975	130	0.052
sensory perception	GO:0007600	101	0.051
reproductive process	GO:0022414	372	0.051
positive regulation of cell communication	GO:0010647	271	0.051
regulation of phosphate metabolic process	GO:0019220	349	0.051
mesoderm formation	GO:0001707	1	0.050
behavior	GO:0007610	205	0.050
brain development	GO:0007420	247	0.050
carbohydrate derivative metabolic process	GO:1901135	346	0.050
regulation of lipid kinase activity	GO:0043550	7	0.049
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	51	0.049
tissue development	GO:0009888	252	0.049
positive regulation of response to stimulus	GO:0048584	285	0.049
cellular component movement	GO:0006928	248	0.049
reproductive system development	GO:0061458	128	0.048
cell migration	GO:0016477	197	0.048
cellular lipid metabolic process	GO:0044255	208	0.047
positive regulation of cell differentiation	GO:0045597	217	0.047
nephric duct development	GO:0072176	1	0.047
cation transport	GO:0006812	382	0.047
regulation of cellular amino acid metabolic process	GO:0006521	2	0.047
macromolecule localization	GO:0033036	252	0.046
striated muscle tissue development	GO:0014706	58	0.046
gastrulation	GO:0007369	2	0.046
response to monosaccharide	GO:0034284	159	0.046
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.045
smooth muscle contraction	GO:0006939	37	0.045
single organism biosynthetic process	GO:0044711	342	0.044
g protein coupled receptor signaling pathway	GO:0007186	242	0.044
nucleic acid templated transcription	GO:0097659	379	0.043
cell morphogenesis involved in differentiation	GO:0000904	119	0.043
immune system process	GO:0002376	204	0.042	Human
cation homeostasis	GO:0055080	195	0.042
cellular homeostasis	GO:0019725	252	0.042
synaptic transmission	GO:0007268	235	0.042
cardiac ventricle development	GO:0003231	1	0.041
organophosphate biosynthetic process	GO:0090407	143	0.041
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.041
cellular component biogenesis	GO:0044085	368	0.041
response to growth factor	GO:0070848	189	0.041
transcription dna templated	GO:0006351	377	0.041
mesonephros development	GO:0001823	14	0.040
growth	GO:0040007	165	0.040
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.040
positive regulation of hormone secretion	GO:0046887	65	0.040
positive regulation of biosynthetic process	GO:0009891	319	0.039
taxis	GO:0042330	67	0.039
intracellular signal transduction	GO:0035556	314	0.039
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.039
response to cocaine	GO:0042220	39	0.038
organ formation	GO:0048645	3	0.038
ureteric bud development	GO:0001657	14	0.038
response to metal ion	GO:0010038	253	0.038
single organism membrane organization	GO:0044802	74	0.037
positive regulation of rna metabolic process	GO:0051254	203	0.037
dopamine secretion	GO:0014046	15	0.037
nucleotide metabolic process	GO:0009117	279	0.036
carbohydrate homeostasis	GO:0033500	75	0.036
circulatory system process	GO:0003013	183	0.036
protein complex biogenesis	GO:0070271	263	0.035
response to ammonium ion	GO:0060359	71	0.035
nitrogen compound transport	GO:0071705	229	0.034
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.034
macromolecular complex subunit organization	GO:0043933	339	0.034
forebrain development	GO:0030900	98	0.034
multi organism reproductive process	GO:0044703	262	0.034
regulation of multicellular organismal development	GO:2000026	376	0.034
ion homeostasis	GO:0050801	212	0.033
behavioral response to nicotine	GO:0035095	2	0.033
potassium ion transmembrane transport	GO:0071805	71	0.033
macromolecular complex assembly	GO:0065003	273	0.033
positive regulation of transcription dna templated	GO:0045893	197	0.033
secretion	GO:0046903	307	0.033
heart development	GO:0007507	72	0.033
regulation of peptide transport	GO:0090087	87	0.033
cellular component assembly	GO:0022607	360	0.033
cyclic nucleotide metabolic process	GO:0009187	80	0.033
regulation of nucleic acid templated transcription	GO:1903506	380	0.033
regulation of synaptic transmission	GO:0050804	141	0.032
cellular ion homeostasis	GO:0006873	184	0.032
formation of primary germ layer	GO:0001704	1	0.032
multicellular organism reproduction	GO:0032504	233	0.032
positive regulation of gene expression	GO:0010628	244	0.032
positive regulation of developmental process	GO:0051094	283	0.032
regulation of hormone levels	GO:0010817	187	0.032
positive regulation of phosphorylation	GO:0042327	177	0.032
vascular process in circulatory system	GO:0003018	96	0.032
response to peptide hormone	GO:0043434	278	0.032
purine nucleotide metabolic process	GO:0006163	229	0.031
regulation of catecholamine secretion	GO:0050433	32	0.031
axonogenesis	GO:0007409	71	0.031
regulation of cellular ketone metabolic process	GO:0010565	27	0.030
cytoskeleton organization	GO:0007010	111	0.030
negative regulation of neuron differentiation	GO:0045665	62	0.030
establishment of protein localization	GO:0045184	141	0.030
anatomical structure morphogenesis	GO:0009653	298	0.030
regulation of blood circulation	GO:1903522	110	0.030
protein localization	GO:0008104	191	0.030
cell part morphogenesis	GO:0032990	123	0.030
mesonephric tubule development	GO:0072164	14	0.030
divalent metal ion transport	GO:0070838	132	0.029
nucleoside phosphate metabolic process	GO:0006753	283	0.029
organic hydroxy compound transport	GO:0015850	77	0.029
divalent inorganic cation homeostasis	GO:0072507	165	0.029
negative regulation of neuron death	GO:1901215	69	0.029
cellular amine metabolic process	GO:0044106	38	0.029
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029
positive regulation of secretion by cell	GO:1903532	128	0.029
feeding behavior	GO:0007631	53	0.029
protein oligomerization	GO:0051259	191	0.029
action potential	GO:0001508	54	0.029
regulation of secretion by cell	GO:1903530	208	0.028
negative regulation of amine transport	GO:0051953	24	0.028
gliogenesis	GO:0042063	93	0.028
striated muscle contraction	GO:0006941	44	0.028
regulation of transferase activity	GO:0051338	123	0.028
oxoacid metabolic process	GO:0043436	290	0.028
cellular macromolecule localization	GO:0070727	122	0.028
positive regulation of amine transport	GO:0051954	26	0.028
ribonucleotide metabolic process	GO:0009259	231	0.027
catabolic process	GO:0009056	351	0.027
reproduction	GO:0000003	245	0.027
regulation of fat cell differentiation	GO:0045598	3	0.027
apoptotic process	GO:0006915	381	0.027
regulation of peptide hormone secretion	GO:0090276	80	0.027
synaptic transmission cholinergic	GO:0007271	11	0.027
cell projection organization	GO:0030030	302	0.027
response to corticosteroid	GO:0031960	235	0.027
neuron development	GO:0048666	286	0.027
inorganic cation transmembrane transport	GO:0098662	202	0.027
response to estradiol	GO:0032355	164	0.027
negative regulation of cellular metabolic process	GO:0031324	281	0.026
positive regulation of protein metabolic process	GO:0051247	178	0.026
response to glucose	GO:0009749	136	0.026
cell motility	GO:0048870	202	0.026
digestive tract mesoderm development	GO:0007502	1	0.026
response to ethanol	GO:0045471	162	0.026
regulation of developmental growth	GO:0048638	45	0.026
regulation of secretion	GO:0051046	224	0.026
negative regulation of neurogenesis	GO:0050768	78	0.026
response to acid chemical	GO:0001101	222	0.026
multicellular organismal reproductive process	GO:0048609	233	0.026
smooth muscle cell proliferation	GO:0048659	77	0.025
purine ribonucleotide biosynthetic process	GO:0009152	81	0.025
cellular response to endogenous stimulus	GO:0071495	377	0.025
positive regulation of immune response	GO:0050778	42	0.025
s shaped body morphogenesis	GO:0072050	2	0.025
telencephalon development	GO:0021537	62	0.025
neuron apoptotic process	GO:0051402	88	0.025
response to vitamin	GO:0033273	131	0.025
muscle cell proliferation	GO:0033002	84	0.025
negative regulation of programmed cell death	GO:0043069	183	0.024
catecholamine secretion	GO:0050432	33	0.024
regulation of tolerance induction dependent upon immune response	GO:0002652	1	0.024
peptide hormone secretion	GO:0030072	84	0.024
amide transport	GO:0042886	105	0.024
single organism reproductive process	GO:0044702	297	0.024
multi multicellular organism process	GO:0044706	138	0.024
cellular response to acid chemical	GO:0071229	75	0.024
ion transmembrane transport	GO:0034220	365	0.023
potassium ion transport	GO:0006813	97	0.023
protein complex subunit organization	GO:0071822	302	0.023
regulation of kinase activity	GO:0043549	117	0.023
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.023
cellular response to organic cyclic compound	GO:0071407	202	0.023
eye morphogenesis	GO:0048592	4	0.023
organophosphate metabolic process	GO:0019637	370	0.023
cellular response to hormone stimulus	GO:0032870	247	0.023
glucose homeostasis	GO:0042593	75	0.023
phospholipid metabolic process	GO:0006644	61	0.022
positive regulation of molecular function	GO:0044093	230	0.022
negative regulation of nervous system development	GO:0051961	79	0.022
hematopoietic progenitor cell differentiation	GO:0002244	2	0.022
regulation of cell differentiation	GO:0045595	320	0.022
developmental process involved in reproduction	GO:0003006	159	0.022
cellular component morphogenesis	GO:0032989	155	0.022
hormone transport	GO:0009914	121	0.022
development of primary female sexual characteristics	GO:0046545	56	0.022
microvillus assembly	GO:0030033	2	0.022
developmental growth	GO:0048589	100	0.022
glial cell differentiation	GO:0010001	65	0.022
cardiac chamber development	GO:0003205	1	0.022
positive regulation of signaling	GO:0023056	270	0.022
rhythmic process	GO:0048511	156	0.022
single organism behavior	GO:0044708	130	0.022
cell communication by chemical coupling	GO:0010643	2	0.021
cell fate determination	GO:0001709	2	0.021
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.021
regulation of membrane potential	GO:0042391	110	0.021
single organism carbohydrate metabolic process	GO:0044723	118	0.021
catecholamine transport	GO:0051937	37	0.021
heart contraction	GO:0060047	57	0.021
regulation of protein metabolic process	GO:0051246	289	0.021
regulation of immune system process	GO:0002682	123	0.021	Human
negative regulation of cellular biosynthetic process	GO:0031327	161	0.021
response to nutrient	GO:0007584	248	0.021
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	3	0.021
cellular chemical homeostasis	GO:0055082	247	0.021
cellular response to organonitrogen compound	GO:0071417	197	0.021
negative regulation of cell development	GO:0010721	82	0.021
negative regulation of transport	GO:0051051	136	0.021
nucleoside phosphate biosynthetic process	GO:1901293	102	0.021
positive regulation of peptide hormone secretion	GO:0090277	50	0.020
hair follicle development	GO:0001942	2	0.020
regulation of ion transport	GO:0043269	245	0.020
sexual reproduction	GO:0019953	148	0.020
mesenchymal to epithelial transition	GO:0060231	3	0.020
negative regulation of osteoblast differentiation	GO:0045668	2	0.020
regulation of apoptotic process	GO:0042981	335	0.020
neurotransmitter uptake	GO:0001504	3	0.020
reproductive structure development	GO:0048608	128	0.020
cell projection morphogenesis	GO:0048858	123	0.020
negative regulation of biosynthetic process	GO:0009890	168	0.020
immune response	GO:0006955	104	0.020
programmed cell death	GO:0012501	392	0.020
regulation of neuronal synaptic plasticity	GO:0048168	31	0.019
chemosensory behavior	GO:0007635	2	0.019
cellular response to oxygen levels	GO:0071453	60	0.019
regulation of growth	GO:0040008	105	0.019
hair cycle process	GO:0022405	2	0.019
regulation of peptide secretion	GO:0002791	82	0.019
positive regulation of cellular component organization	GO:0051130	200	0.019
mesoderm morphogenesis	GO:0048332	1	0.019
regulation of blood pressure	GO:0008217	83	0.019
cellular response to stress	GO:0033554	269	0.019
neuron projection development	GO:0031175	273	0.019
regulation of calcium ion transport	GO:0051924	77	0.019
single organism catabolic process	GO:0044712	283	0.019
protein complex assembly	GO:0006461	263	0.018
vesicle mediated transport	GO:0016192	181	0.018
muscle structure development	GO:0061061	87	0.018
ventricular cardiac muscle cell action potential	GO:0086005	2	0.018
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.018
tolerance induction to nonself antigen	GO:0002462	2	0.018
negative regulation of protein metabolic process	GO:0051248	114	0.018
multicellular organism growth	GO:0035264	1	0.018
thyroid gland development	GO:0030878	1	0.018
negative regulation of secretion	GO:0051048	82	0.018
g protein coupled purinergic receptor signaling pathway	GO:0035588	8	0.018
positive regulation of cell proliferation	GO:0008284	249	0.018
regulation of catalytic activity	GO:0050790	304	0.018
negative regulation of rna metabolic process	GO:0051253	123	0.017
negative regulation of signaling	GO:0023057	157	0.017
cellular catabolic process	GO:0044248	295	0.017
positive regulation of secretion	GO:0051047	140	0.017
regulation of anatomical structure size	GO:0090066	135	0.017
membrane organization	GO:0061024	94	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.017
localization of cell	GO:0051674	202	0.017
positive regulation of cellular protein metabolic process	GO:0032270	167	0.017
metal ion transport	GO:0030001	289	0.017
regulation of nervous system development	GO:0051960	264	0.017
multicellular organismal signaling	GO:0035637	44	0.017
response to zinc ion	GO:0010043	39	0.017
locomotion	GO:0040011	237	0.017
cellular response to vitamin e	GO:0071306	3	0.017
cellular metal ion homeostasis	GO:0006875	172	0.017
immune system development	GO:0002520	41	0.017
organ morphogenesis	GO:0009887	75	0.017
positive regulation of cell motility	GO:2000147	97	0.017
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.017
metanephric glomerulus development	GO:0072224	3	0.017
response to estrogen	GO:0043627	232	0.017
positive regulation of peptide secretion	GO:0002793	52	0.017
male sex differentiation	GO:0046661	64	0.017
cellular response to nitrogen compound	GO:1901699	210	0.017
cellular response to insulin stimulus	GO:0032869	81	0.017
defense response	GO:0006952	194	0.017
sex differentiation	GO:0007548	113	0.016
neuron death	GO:0070997	127	0.016
nucleotide biosynthetic process	GO:0009165	98	0.016
regulation of cell development	GO:0060284	263	0.016
regulation of insulin secretion	GO:0050796	65	0.016
organelle organization	GO:0006996	266	0.016
carbohydrate derivative biosynthetic process	GO:1901137	124	0.016
protein heterooligomerization	GO:0051291	89	0.016
regulation of transporter activity	GO:0032409	50	0.016
cellular calcium ion homeostasis	GO:0006874	160	0.016
transmission of nerve impulse	GO:0019226	42	0.016
negative regulation of developmental process	GO:0051093	125	0.016
positive regulation of lipid metabolic process	GO:0045834	33	0.016
olfactory behavior	GO:0042048	2	0.016
kidney morphogenesis	GO:0060993	13	0.016
cell adhesion	GO:0007155	110	0.016
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.016
response to insulin	GO:0032868	133	0.016
comma shaped body morphogenesis	GO:0072049	2	0.016
regulation of epithelial cell differentiation	GO:0030856	12	0.016
regulation of protein phosphorylation	GO:0001932	183	0.016
signal release	GO:0023061	145	0.016
grooming behavior	GO:0007625	4	0.015
hair cycle	GO:0042633	3	0.015
positive regulation of intracellular signal transduction	GO:1902533	138	0.015
negative regulation of neuron apoptotic process	GO:0043524	45	0.015
peptide biosynthetic process	GO:0043043	3	0.015
regulation of embryonic development	GO:0045995	2	0.015
inflammatory response	GO:0006954	150	0.015
actin filament based process	GO:0030029	86	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
amine metabolic process	GO:0009308	38	0.015
regulation of cellular amine metabolic process	GO:0033238	8	0.015
regulation of cellular component organization	GO:0051128	368	0.015
cardiac muscle tissue development	GO:0048738	26	0.015
negative regulation of secretion by cell	GO:1903531	72	0.015
response to nicotine	GO:0035094	51	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.015
cardiac muscle tissue morphogenesis	GO:0055008	1	0.015
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.015
regulation of blood vessel size	GO:0050880	89	0.015
skeletal muscle cell differentiation	GO:0035914	2	0.015
regulation of response to wounding	GO:1903034	69	0.014
positive regulation of transport	GO:0051050	245	0.014
positive regulation of kinase activity	GO:0033674	77	0.014
positive regulation of catalytic activity	GO:0043085	184	0.014
neuron projection morphogenesis	GO:0048812	122	0.014
negative regulation of cell differentiation	GO:0045596	99	0.014
neuron fate commitment	GO:0048663	4	0.014
calcium ion transport	GO:0006816	131	0.014
response to calcium ion	GO:0051592	59	0.014
insulin secretion	GO:0030073	69	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
response to heat	GO:0009408	60	0.014
sympathetic nervous system development	GO:0048485	1	0.014
wound healing	GO:0042060	122	0.014
regulation of camp biosynthetic process	GO:0030817	38	0.014
intracellular transport	GO:0046907	185	0.014
ovulation cycle	GO:0042698	67	0.014
positive regulation of mapk cascade	GO:0043410	92	0.014
epithelial tube formation	GO:0072175	3	0.014
aging	GO:0007568	241	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.014
sensory perception of pain	GO:0019233	73	0.014
inorganic ion transmembrane transport	GO:0098660	229	0.014
response to oxidative stress	GO:0006979	186	0.014
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.014
response to transition metal nanoparticle	GO:1990267	122	0.014
ossification	GO:0001503	70	0.014
regulation of cell cycle	GO:0051726	73	0.014
glycosaminoglycan biosynthetic process	GO:0006024	4	0.014
regulation of nucleotide metabolic process	GO:0006140	117	0.014
positive regulation of protein modification process	GO:0031401	142	0.014
regulation of catabolic process	GO:0009894	113	0.013
oxidation reduction process	GO:0055114	304	0.013
ribose phosphate metabolic process	GO:0019693	235	0.013
negative regulation of apoptotic process	GO:0043066	181	0.013
positive regulation of cellular amine metabolic process	GO:0033240	3	0.013
positive regulation of protein kinase activity	GO:0045860	73	0.013
negative regulation of response to stimulus	GO:0048585	155	0.013
regulation of transcription dna templated	GO:0006355	374	0.013
regulation of cellular localization	GO:0060341	263	0.013
negative regulation of signal transduction in absence of ligand	GO:1901099	3	0.013
regulation of phosphorylation	GO:0042325	248	0.013
cellular response to carbohydrate stimulus	GO:0071322	72	0.013
cellular response to hexose stimulus	GO:0071331	65	0.013
cation transmembrane transport	GO:0098655	263	0.013
protein autophosphorylation	GO:0046777	66	0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.013
negative regulation of molecular function	GO:0044092	133	0.013
spinal cord development	GO:0021510	27	0.013
ensheathment of neurons	GO:0007272	40	0.013
regulation of purine nucleotide metabolic process	GO:1900542	115	0.013
mapk cascade	GO:0000165	140	0.013
adenylate cyclase inhibiting g protein coupled receptor signaling pathway	GO:0007193	19	0.013
cell cycle	GO:0007049	101	0.013
molting cycle process	GO:0022404	2	0.013
glycerolipid metabolic process	GO:0046486	67	0.013
bmp signaling pathway	GO:0030509	4	0.013
gamete generation	GO:0007276	124	0.013
epithelium development	GO:0060429	96	0.013
regulation of neuron apoptotic process	GO:0043523	83	0.013
cellular response to lipid	GO:0071396	201	0.013
heart process	GO:0003015	57	0.013
intracellular protein transport	GO:0006886	79	0.013
ribose phosphate biosynthetic process	GO:0046390	87	0.013
tube development	GO:0035295	89	0.013
nephron tubule formation	GO:0072079	2	0.013
regulation of heart contraction	GO:0008016	48	0.013
tube formation	GO:0035148	3	0.013
regulation of neurogenesis	GO:0050767	247	0.013
negative regulation of rna biosynthetic process	GO:1902679	118	0.013
positive regulation of release of cytochrome c from mitochondria	GO:0090200	3	0.012
calcium ion homeostasis	GO:0055074	162	0.012
positive regulation of transferase activity	GO:0051347	81	0.012
cellular response to growth factor stimulus	GO:0071363	162	0.012
spindle organization	GO:0007051	2	0.012
embryonic epithelial tube formation	GO:0001838	3	0.012
transmembrane transport	GO:0055085	412	0.012
learning	GO:0007612	33	0.012
blood circulation	GO:0008015	183	0.012
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.012
peptide secretion	GO:0002790	86	0.012
adult behavior	GO:0030534	16	0.012
organic hydroxy compound metabolic process	GO:1901615	115	0.012
neuronal action potential	GO:0019228	35	0.012
neuron differentiation	GO:0030182	368	0.012
regulation of transmembrane transporter activity	GO:0022898	49	0.012
anatomical structure maturation	GO:0071695	2	0.012
response to lithium ion	GO:0010226	28	0.012
cardiac muscle cell contraction	GO:0086003	10	0.012
divalent inorganic cation transport	GO:0072511	134	0.012
regulation of response to stress	GO:0080134	126	0.012
regulation of cell growth	GO:0001558	85	0.012
regulation of neuron death	GO:1901214	115	0.012
acute inflammatory response	GO:0002526	58	0.012
muscle cell differentiation	GO:0042692	52	0.012
cellular ketone metabolic process	GO:0042180	51	0.012
negative regulation of innate immune response	GO:0045824	4	0.012
cellular amino acid metabolic process	GO:0006520	107	0.012
immune effector process	GO:0002252	53	0.012
mitotic spindle organization	GO:0007052	2	0.012
cellular amide metabolic process	GO:0043603	44	0.012
lipid storage	GO:0019915	1	0.012
cellular response to peptide	GO:1901653	133	0.012
negative regulation of multicellular organismal metabolic process	GO:0044252	4	0.012
negative regulation of cell communication	GO:0010648	158	0.011
peptide transport	GO:0015833	97	0.011
regulation of metal ion transport	GO:0010959	118	0.011
morphogenesis of embryonic epithelium	GO:0016331	3	0.011
branching morphogenesis of an epithelial tube	GO:0048754	14	0.011
regulation of cellular component movement	GO:0051270	150	0.011
positive regulation of platelet derived growth factor receptor signaling pathway	GO:0010641	1	0.011
purine ribonucleoside monophosphate catabolic process	GO:0009169	55	0.011
endocrine process	GO:0050886	32	0.011
cyclic nucleotide biosynthetic process	GO:0009190	63	0.011
palate development	GO:0060021	2	0.011
neuromuscular process	GO:0050905	2	0.011
maintenance of location	GO:0051235	17	0.011
monoamine transport	GO:0015844	43	0.011

RT1-DOa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
gastrointestinal system disease	DOID:77	0.067
disease of anatomical entity	DOID:7	0.067
nervous system disease	DOID:863	0.051
sensory system disease	DOID:0050155	0.015
central nervous system disease	DOID:331	0.014
brain disease	DOID:936	0.014

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