Rattus norvegicus

0 known processes

RT1-Da

RT1 class II, locus Da

(Aliases: H2-Ea,RT1-u,MGC112637)

RT1-Da biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000250410.992
Human
cellular response to ammonium ionGO:0071242170.991
antigen processing and presentationGO:001988220.986
Human
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.986
antigen processing and presentation of peptide antigenGO:004800220.983
Human
positive regulation of t cell differentiationGO:004558260.981
immune system processGO:00023762040.963
Human
antigen processing and presentation of exogenous antigenGO:001988410.956
regulation of neutrophil migrationGO:190262260.954
regulation of leukocyte proliferationGO:0070663260.951
negative regulation of lymphocyte activationGO:0051250100.940
regulation of t cell proliferationGO:0042129170.930
regulation of t cell activationGO:0050863230.910
mononuclear cell proliferationGO:0032943290.908
antigen processing and presentation of peptide antigen via mhc class iiGO:000249510.906
Human
immunoglobulin mediated immune responseGO:001606440.900
regulation of mononuclear cell proliferationGO:0032944260.881
t cell differentiationGO:003021790.817
b cell mediated immunityGO:001972440.813
t cell activationGO:0042110290.801
cellular response to organic cyclic compoundGO:00714072020.788
regulation of lymphocyte proliferationGO:0050670260.768
lymphocyte activationGO:0046649430.720
negative regulation of t cell proliferationGO:004213050.713
de novo posttranslational protein foldingGO:005108420.702
antigen processing and presentation of exogenous peptide antigenGO:000247810.686
negative regulation of leukocyte proliferationGO:007066460.672
leukocyte activationGO:0045321760.671
positive regulation of lymphocyte activationGO:0051251250.658
regulation of adaptive immune responseGO:000281980.654
leukocyte proliferationGO:0070661290.650
regulation of cell activationGO:0050865500.647
regulation of antigen processing and presentationGO:000257710.647
lymphocyte proliferationGO:0046651290.629
immune responseGO:00069551040.567
response to glucocorticoidGO:00513842230.514
negative regulation of t cell activationGO:005086870.512
positive regulation of chemokine productionGO:003272240.504
regulation of cell proliferationGO:00421273590.501
positive regulation of lymphocyte proliferationGO:0050671200.498
negative regulation of immune system processGO:0002683390.478
cellular response to morphineGO:007131550.465
leukocyte migrationGO:0050900380.463
t cell proliferationGO:0042098190.461
regulation of secretionGO:00510462240.447
positive regulation of t cell activationGO:0050870170.446
innate immune responseGO:0045087350.429
defense responseGO:00069521940.426
response to interferon gammaGO:0034341200.418
regulation of immune system processGO:00026821230.417
response to cytokineGO:00340972150.392
chaperone mediated protein folding requiring cofactorGO:005108520.382
positive regulation of leukocyte activationGO:0002696300.374
lymphocyte differentiationGO:0030098100.364
programmed cell deathGO:00125013920.360
negative regulation of mononuclear cell proliferationGO:003294560.343
granulocyte chemotaxisGO:0071621150.338
response to fungusGO:000962080.317
positive regulation of cell motilityGO:2000147970.316
positive regulation of leukocyte differentiationGO:1902107130.305
regulation of leukocyte activationGO:0002694450.301
mapk cascadeGO:00001651400.288
cellular amino acid metabolic processGO:00065201070.285
positive regulation of lymphocyte differentiationGO:004562160.277
cell activationGO:0001775970.277
myeloid leukocyte cytokine productionGO:006108210.276
cellular response to endogenous stimulusGO:00714953770.274
negative regulation of leukocyte activationGO:0002695140.269
protein foldingGO:0006457120.268
cellular response to steroid hormone stimulusGO:0071383930.268
positive regulation of cytokine productionGO:0001819420.264
response to symbiontGO:000960810.255
chemotaxisGO:0006935660.249
negative regulation of lymphocyte proliferationGO:005067260.245
cellular response to lipidGO:00713962010.243
interleukin 1 beta secretionGO:005070230.220
positive regulation of multicellular organismal processGO:00512403870.218
response to other organismGO:00517072200.216
cellular response to isoquinoline alkaloidGO:007131760.216
negative regulation of cell activationGO:0050866150.200
regulation of leukocyte differentiationGO:1902105200.190
response to dexamethasoneGO:0071548490.190
immune effector processGO:0002252530.188
regulation of programmed cell deathGO:00430673410.182
positive regulation of neutrophil chemotaxisGO:009002350.176
leukocyte differentiationGO:0002521300.175
positive regulation of immune system processGO:0002684900.173
positive regulation of developmental processGO:00510942830.165
positive regulation of immune responseGO:0050778420.163
de novo protein foldingGO:000645820.163
cellular response to cytokine stimulusGO:00713451270.158
carboxylic acid metabolic processGO:00197522890.157
positive regulation of cell communicationGO:00106472710.156
cellular response to stressGO:00335542690.155
apoptotic processGO:00069153810.153
cellular response to alcoholGO:0097306870.151
macromolecular complex subunit organizationGO:00439333390.150
Human
protein complex biogenesisGO:00702712630.146
Human
negative regulation of multicellular organismal processGO:00512412030.144
macromolecular complex assemblyGO:00650032730.144
Human
regulation of t cell differentiationGO:004558070.144
regulation of leukocyte migrationGO:0002685240.138
lymphocyte mediated immunityGO:0002449140.138
regulation of apoptotic processGO:00429813350.137
regulation of cellular ketone metabolic processGO:0010565270.134
multicellular organismal homeostasisGO:0048871490.133
positive regulation of mononuclear cell proliferationGO:0032946200.132
protein complex subunit organizationGO:00718223020.126
Human
response to biotic stimulusGO:00096072260.124
protein transportGO:00150311320.120
immune system developmentGO:0002520410.119
cellular component biogenesisGO:00440853680.119
Human
positive regulation of cell deathGO:00109421840.115
cellular response to corticosteroid stimulusGO:0071384690.115
leukocyte mediated immunityGO:0002443280.115
response to corticosteroidGO:00319602350.114
regulation of kinase activityGO:00435491170.110
organic acid metabolic processGO:00060822920.109
negative regulation of lymphocyte apoptotic processGO:007022910.108
prostaglandin metabolic processGO:0006693120.107
regulation of protein phosphorylationGO:00019321830.107
positive regulation of cell activationGO:0050867340.104
positive regulation of response to external stimulusGO:0032103510.100
cellular response to nitrogen compoundGO:19016992100.098
negative regulation of apoptotic processGO:00430661810.093
neutrophil chemotaxisGO:0030593110.093
response to isoquinoline alkaloidGO:0014072280.092
positive regulation of leukocyte chemotaxisGO:0002690100.092
fatty acid derivative metabolic processGO:1901568380.091
regulation of alpha beta t cell activationGO:004663420.090
production of molecular mediator of immune responseGO:000244080.089
positive regulation of phosphorylationGO:00423271770.089
cellular response to organonitrogen compoundGO:00714171970.087
negative regulation of cell proliferationGO:00082851190.087
regulation of protein metabolic processGO:00512462890.085
negative regulation of programmed cell deathGO:00430691830.085
regulation of cell differentiationGO:00455953200.084
multicellular organismal reproductive processGO:00486092330.083
t cell selectionGO:004505810.083
positive regulation of cellular component movementGO:00512721020.082
positive regulation of cellular protein metabolic processGO:00322701670.079
response to external biotic stimulusGO:00432072210.078
negative regulation of response to stimulusGO:00485851550.077
regulation of interleukin 1 secretionGO:005070430.076
regulation of cellular amino acid metabolic processGO:000652120.075
regulation of multicellular organismal developmentGO:20000263760.075
lymphocyte homeostasisGO:000226020.074
response to ketoneGO:19016541820.071
lipid biosynthetic processGO:00086101280.070
negative regulation of leukocyte apoptotic processGO:200010740.070
regulation of signal transductionGO:00099663180.070
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282280.070
response to ionizing radiationGO:0010212590.070
cellular ketone metabolic processGO:0042180510.069
negative regulation of cell deathGO:00605482290.068
behaviorGO:00076102050.068
regulation of neutrophil chemotaxisGO:009002250.066
protein phosphorylationGO:00064683450.066
cellular lipid metabolic processGO:00442552080.065
cellular response to external stimulusGO:00714961180.065
cell type specific apoptotic processGO:00972851340.064
regulation of locomotionGO:00400121480.063
regulation of lymphocyte activationGO:0051249340.063
negative regulation of signal transductionGO:0009968830.063
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282460.063
regulation of homeostatic processGO:00328441010.062
cell killingGO:0001906130.062
cellular response to hormone stimulusGO:00328702470.062
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460130.061
response to ammonium ionGO:0060359710.061
adaptive immune responseGO:0002250140.061
positive regulation of cell proliferationGO:00082842490.060
regulation of molecular functionGO:00650093980.060
negative regulation of peptide secretionGO:0002792300.059
icosanoid biosynthetic processGO:0046456180.058
regulation of transferase activityGO:00513381230.058
cellular component assemblyGO:00226073600.057
Human
positive regulation of cellular amino acid metabolic processGO:004576410.057
cellular response to oxygen containing compoundGO:19017013860.056
peptide secretionGO:0002790860.055
organic acid biosynthetic processGO:0016053830.053
regulation of phosphorylationGO:00423252480.053
positive regulation of cell migrationGO:0030335960.052
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.052
positive regulation of neutrophil migrationGO:190262460.052
fatty acid derivative biosynthetic processGO:1901570180.051
icosanoid metabolic processGO:0006690380.051
positive regulation of cellular amine metabolic processGO:003324030.051
homeostatic processGO:00425923310.050
lipid metabolic processGO:00066292830.050
localization of cellGO:00516742020.048
positive regulation of programmed cell deathGO:00430681570.047
central nervous system developmentGO:00074173110.047
hemopoiesisGO:0030097340.047
positive regulation of mapk cascadeGO:0043410920.046
positive regulation of immune effector processGO:0002699190.046
apoptotic signaling pathwayGO:0097190270.045
cellular amine metabolic processGO:0044106380.044
cell cell signalingGO:00072673350.044
monocarboxylic acid biosynthetic processGO:0072330480.043
regulation of cellular amine metabolic processGO:003323880.043
intracellular signal transductionGO:00355563140.043
regulation of b cell mediated immunityGO:000271220.043
signal transduction by phosphorylationGO:00230141440.043
negative regulation of signalingGO:00230571570.043
regulation of cellular component movementGO:00512701500.042
hematopoietic or lymphoid organ developmentGO:0048534360.041
amine metabolic processGO:0009308380.041
positive regulation of apoptotic processGO:00430651540.041
positive regulation of cell differentiationGO:00455972170.040
small molecule biosynthetic processGO:00442831240.040
negative regulation of innate immune responseGO:004582440.039
brain developmentGO:00074202470.038
negative regulation of metabolic processGO:00098923310.037
t cell migrationGO:007267820.037
protein complex assemblyGO:00064612630.036
Human
organelle localizationGO:0051640550.036
negative regulation of lymphocyte differentiationGO:004562020.036
regulation of cellular response to stressGO:0080135490.036
positive regulation of leukocyte migrationGO:0002687210.035
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.035
regulation of apoptotic signaling pathwayGO:2001233130.035
positive regulation of response to stimulusGO:00485842850.035
myeloid leukocyte migrationGO:0097529200.035
amide transportGO:00428861050.035
regulation of lymphocyte differentiationGO:004561980.035
cellular response to glucocorticoid stimulusGO:0071385680.034
regulation of leukocyte chemotaxisGO:0002688120.034
cation homeostasisGO:00550801950.034
sequestering of metal ionGO:005123890.033
positive regulation of behaviorGO:0048520380.033
activation of mapk activityGO:0000187330.032
negative regulation of cell communicationGO:00106481580.032
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.032
response to radiationGO:00093141370.032
cellular response to alkaloidGO:0071312250.031
unsaturated fatty acid metabolic processGO:0033559390.031
fatty acid biosynthetic processGO:0006633330.031
regulation of anatomical structure morphogenesisGO:00226031410.031
neuron differentiationGO:00301823680.031
cellular protein localizationGO:00346131220.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
anterior posterior pattern specificationGO:000995210.030
cellular response to starvationGO:0009267270.030
regulation of peptide secretionGO:0002791820.029
positive regulation of granulocyte chemotaxisGO:007162460.029
multi organism reproductive processGO:00447032620.029
regulation of phosphate metabolic processGO:00192203490.029
positive regulation of t cell migrationGO:200040610.029
response to retinoic acidGO:0032526630.029
positive regulation of chemotaxisGO:0050921230.028
metal ion transportGO:00300012890.028
peptidyl tyrosine modificationGO:0018212720.028
cell morphogenesisGO:00009021420.028
regulation of behaviorGO:0050795610.028
muscle cell differentiationGO:0042692520.028
response to monosaccharideGO:00342841590.027
regulation of response to stressGO:00801341260.027
positive regulation of b cell proliferationGO:003089060.027
response to estradiolGO:00323551640.027
negative regulation of nitrogen compound metabolic processGO:00511721610.026
regulation of secretion by cellGO:19035302080.026
unsaturated fatty acid biosynthetic processGO:0006636210.026
anatomical structure morphogenesisGO:00096532980.026
regulation of b cell proliferationGO:003088860.026
positive regulation of isotype switching to igg isotypesGO:004830410.026
cell projection organizationGO:00300303020.026
positive regulation of fibroblast proliferationGO:0048146150.026
regulation of cell migrationGO:00303341280.025
negative regulation of homeostatic processGO:0032845470.025
negative regulation of cell differentiationGO:0045596990.025
cell motilityGO:00488702020.025
neuron deathGO:00709971270.025
response to inorganic substanceGO:00100353770.025
positive regulation of locomotionGO:00400171020.025
negative regulation of developmental processGO:00510931250.025
red far red light phototransductionGO:000958510.024
regulation of response to external stimulusGO:00321011060.024
positive regulation of map kinase activityGO:0043406460.024
cation transportGO:00068123820.024
carboxylic acid biosynthetic processGO:0046394830.024
cell migrationGO:00164771970.024
regulation of phosphorus metabolic processGO:00511743490.024
positive regulation of transportGO:00510502450.023
taxisGO:0042330670.023
granulocyte migrationGO:0097530160.023
leukocyte apoptotic processGO:007188760.023
response to acid chemicalGO:00011012220.023
regulation of immunoglobulin productionGO:000263740.023
regulation of production of molecular mediator of immune responseGO:000270070.023
positive regulation of molecular functionGO:00440932300.023
positive regulation of phosphorus metabolic processGO:00105622620.022
ear developmentGO:0043583210.022
axon developmentGO:0061564960.022
regulation of cytokine productionGO:0001817560.022
cellular response to dexamethasone stimulusGO:0071549360.021
positive regulation of protein phosphorylationGO:00019341350.021
positive regulation of phosphate metabolic processGO:00459372620.021
establishment of protein localizationGO:00451841410.021
positive regulation of kinase activityGO:0033674770.021
regulation of map kinase activityGO:0043405530.021
response to reactive oxygen speciesGO:00003021200.021
prostaglandin biosynthetic processGO:0001516120.020
leukocyte chemotaxisGO:0030595220.020
positive regulation of adaptive immune responseGO:000282160.020
head developmentGO:00603222470.020
secretionGO:00469033070.020
regulation of immune effector processGO:0002697320.020
signal releaseGO:00230611450.019
regulation of peptide transportGO:0090087870.019
agingGO:00075682410.019
neutrophil migrationGO:1990266120.019
regulation of cellular protein metabolic processGO:00322682670.019
actin filament branchingGO:009013510.019
cellular amide metabolic processGO:0043603440.019
cellular response to acid chemicalGO:0071229750.019
regulation of protein modification processGO:00313991940.019
activation of protein kinase activityGO:0032147470.018
negative regulation of macromolecule metabolic processGO:00106052600.018
proteolysisGO:00065081750.018
organic substance catabolic processGO:19015753160.018
protein maturationGO:0051604680.018
positive regulation of cellular biosynthetic processGO:00313282950.018
mitotic spindle organizationGO:000705220.018
biological adhesionGO:00226101100.018
nitrogen compound transportGO:00717052290.018
urogenital system developmentGO:0001655780.017
response to glucoseGO:00097491360.017
response to toxic substanceGO:00096361330.017
positive regulation of protein modification processGO:00314011420.017
regulation of heart morphogenesisGO:200082620.017
calcium ion homeostasisGO:00550741620.017
positive regulation of immunoglobulin productionGO:000263940.017
response to calcium ionGO:0051592590.017
regulation of erk1 and erk2 cascadeGO:0070372410.017
positive regulation of stress activated mapk cascadeGO:0032874170.017
single organism behaviorGO:00447081300.017
response to growth factorGO:00708481890.016
salivary gland developmentGO:000743130.016
negative regulation of gene expressionGO:00106291990.016
oxoacid metabolic processGO:00434362900.016
single organism cell adhesionGO:0098602460.016
cellular component movementGO:00069282480.016
sleepGO:0030431300.016
positive regulation of t cell mediated cytotoxicityGO:000191640.016
endocytosisGO:0006897840.016
peptide biosynthetic processGO:004304330.016
negative regulation of cellular metabolic processGO:00313242810.016
positive regulation of t cell mediated immunityGO:000271140.015
regulation of granulocyte chemotaxisGO:007162280.015
cellular response to extracellular stimulusGO:0031668730.015
positive regulation of t cell proliferationGO:0042102120.015
chaperone mediated protein foldingGO:006107760.015
b cell activation involved in immune responseGO:000231210.015
cell part morphogenesisGO:00329901230.015
positive regulation of transcription factor import into nucleusGO:004299340.015
tissue developmentGO:00098882520.015
positive regulation of signalingGO:00230562700.015
fibroblast proliferationGO:0048144220.015
regulation of tolerance induction to nonself antigenGO:000265510.015
leukocyte cell cell adhesionGO:000715940.014
regulation of stress activated protein kinase signaling cascadeGO:0070302230.014
purine nucleobase metabolic processGO:000614440.014
regulation of cell motilityGO:20001451310.014
positive regulation of tolerance induction dependent upon immune responseGO:000265410.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
somatic diversification of immunoglobulins involved in immune responseGO:000220810.014
positive regulation of isotype switchingGO:004583010.014
defense response to gram negative bacteriumGO:005082930.014
regulation of proteolysisGO:0030162660.014
circulatory system developmentGO:00723591340.014
transforming growth factor beta1 productionGO:003290520.014
response to extracellular stimulusGO:00099913800.014
prostanoid metabolic processGO:0006692120.014
regulation of neurogenesisGO:00507672470.014
regulation of stress activated mapk cascadeGO:0032872230.013
male sex determinationGO:003023820.013
reactive nitrogen species metabolic processGO:200105710.013
t cell differentiation in thymusGO:003307740.013
negative regulation of cellular biosynthetic processGO:00313271610.013
positive regulation of transferase activityGO:0051347810.013
cellular metal ion homeostasisGO:00068751720.013
protein processingGO:0016485680.013
negative regulation of intracellular signal transductionGO:1902532380.013
kidney developmentGO:0001822670.013
response to hexoseGO:00097461440.013
peptidyl tyrosine phosphorylationGO:0018108720.013
cellular catabolic processGO:00442482950.013
peptide hormone secretionGO:0030072840.013
catabolic processGO:00090563510.013
ras protein signal transductionGO:0007265290.013
fatty acid metabolic processGO:0006631990.013
response to carbohydrateGO:00097431830.013
muscle system processGO:00030121150.013
negative regulation of response to external stimulusGO:0032102370.013
secretion by cellGO:00329402480.013
organ regenerationGO:00311001010.012
response to osmotic stressGO:0006970420.012
autophagic cell deathGO:004810240.012
hematopoietic progenitor cell differentiationGO:000224420.012
positive regulation of homotypic cell cell adhesionGO:003411220.012
regulation of cell developmentGO:00602842630.012
syncytium formationGO:000694940.012
axonogenesisGO:0007409710.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124320.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
maintenance of locationGO:0051235170.012
macrophage chemotaxisGO:004824620.012
cellular homeostasisGO:00197252520.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
negative regulation of secretionGO:0051048820.012
cytoskeleton organizationGO:00070101110.012
axis specificationGO:000979840.012
ribose phosphate metabolic processGO:00196932350.012
positive regulation of intracellular signal transductionGO:19025331380.011
cellular hormone metabolic processGO:0034754490.011
tolerance induction to nonself antigenGO:000246220.011
cellular response to growth factor stimulusGO:00713631620.011
neurological system processGO:00508772190.011
Human
response to purine containing compoundGO:00140741260.011
single organism biosynthetic processGO:00447113420.011
positive regulation of leukocyte mediated immunityGO:0002705130.011
organonitrogen compound biosynthetic processGO:19015661670.011
eye pigment metabolic processGO:004244110.011
secondary metabolic processGO:0019748150.011
regulation of ion transportGO:00432692450.011
spindle organizationGO:000705120.011
dna recombinationGO:000631030.011
regulation of protein kinase activityGO:00458591050.011
negative regulation of rna metabolic processGO:00512531230.011
cellular calcium ion homeostasisGO:00068741600.011
positive regulation of secretionGO:00510471400.011
regulation of immune responseGO:0050776550.011
intracellular protein transportGO:0006886790.011
regulation of peptidase activityGO:0052547550.011
regulation of cellular localizationGO:00603412630.011
toxin transportGO:190199830.011
inflammatory responseGO:00069541500.011
response to metal ionGO:00100382530.011
triglyceride homeostasisGO:007032820.011
carbohydrate derivative metabolic processGO:19011353460.011
regulation of mapk cascadeGO:00434081160.011
t cell receptor signaling pathwayGO:005085210.011
lipid storageGO:001991510.011
regulation of lymphocyte migrationGO:200040110.010
regulation of b cell differentiationGO:004557710.010
dorsal ventral pattern formationGO:000995340.010
insulin secretionGO:0030073690.010
negative regulation of defense responseGO:0031348190.010
cell cycleGO:00070491010.010
negative regulation of transportGO:00510511360.010
sensory organ developmentGO:0007423740.010
regulation of immunoglobulin mediated immune responseGO:000288920.010
cell cell signaling involved in cell fate commitmentGO:004516820.010

RT1-Da disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
congenital hypothyroidismDOID:005032800.012
endocrine system diseaseDOID:2800.012
hypothyroidismDOID:145900.012
thyroid gland diseaseDOID:5000.012