Rattus norvegicus

68 known processes

Gpx4

glutathione peroxidase 4

(Aliases: gpx-4,Phgpx,snGpx)

Gpx4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to oxidative stressGO:00069791860.485
catabolic processGO:00090563510.446
response to inorganic substanceGO:00100353770.341
response to extracellular stimulusGO:00099913800.340
regulation of neuron differentiationGO:00456642080.252
regulation of cell developmentGO:00602842630.242
response to cytokineGO:00340972150.241
behaviorGO:00076102050.239
single organism reproductive processGO:00447022970.238
Mouse
cellular amide metabolic processGO:0043603440.236
glutathione metabolic processGO:0006749150.234
reproductive processGO:00224143720.232
Mouse
cellular calcium ion homeostasisGO:00068741600.205
agingGO:00075682410.203
lipid metabolic processGO:00066292830.196
regulation of neurogenesisGO:00507672470.185
regulation of cellular component movementGO:00512701500.178
positive regulation of cellular biosynthetic processGO:00313282950.176
response to metal ionGO:00100382530.175
organic acid metabolic processGO:00060822920.175
response to hydrogen peroxideGO:0042542890.158
cellular catabolic processGO:00442482950.157
response to glucocorticoidGO:00513842230.148
cellular response to oxidative stressGO:0034599760.148
apoptotic processGO:00069153810.146
developmental process involved in reproductionGO:00030061590.144
positive regulation of cell communicationGO:00106472710.140
cation transportGO:00068123820.137
regulation of nervous system developmentGO:00519602640.132
regulation of cell differentiationGO:00455953200.132
single organism catabolic processGO:00447122830.129
programmed cell deathGO:00125013920.129
multicellular organismal reproductive processGO:00486092330.127
Mouse
metal ion transportGO:00300012890.123
multi organism reproductive processGO:00447032620.123
Mouse
cell cell signalingGO:00072673350.120
response to corticosteroidGO:00319602350.120
carboxylic acid metabolic processGO:00197522890.120
regulation of synaptic transmissionGO:00508041410.117
positive regulation of response to stimulusGO:00485842850.115
protein phosphorylationGO:00064683450.115
response to nutrientGO:00075842480.110
cell cycle checkpointGO:000007520.109
regulation of ion transportGO:00432692450.107
cation homeostasisGO:00550801950.106
cellular response to reactive oxygen speciesGO:0034614550.104
response to toxic substanceGO:00096361330.102
neuron differentiationGO:00301823680.101
macromolecular complex subunit organizationGO:00439333390.099
Mouse
cellular response to stressGO:00335542690.098
organonitrogen compound biosynthetic processGO:19015661670.096
response to reactive oxygen speciesGO:00003021200.096
single organism intracellular transportGO:19025821660.095
response to woundingGO:00096112540.091
cell projection organizationGO:00300303020.091
regulation of cellular component organizationGO:00511283680.090
negative regulation of cell deathGO:00605482290.090
organic substance catabolic processGO:19015753160.089
response to other organismGO:00517072200.088
cellular response to nitrogen compoundGO:19016992100.087
response to biotic stimulusGO:00096072260.087
cellular response to endogenous stimulusGO:00714953770.086
brain developmentGO:00074202470.086
tetrapyrrole metabolic processGO:0033013110.084
central nervous system developmentGO:00074173110.083
regulation of protein phosphorylationGO:00019321830.081
cytoskeleton organizationGO:00070101110.080
reproductionGO:00000032450.080
Mouse
gonad developmentGO:00084061040.079
regulation of protein modification processGO:00313991940.078
response to estrogenGO:00436272320.078
reproductive structure developmentGO:00486081280.075
response to nutrient levelsGO:00316673700.075
regulation of phosphorylationGO:00423252480.073
cellular cation homeostasisGO:00300031800.073
response to peptide hormoneGO:00434342780.072
regulation of phosphate metabolic processGO:00192203490.072
intracellular signal transductionGO:00355563140.072
monovalent inorganic cation transportGO:00156721720.071
regulation of cell projection organizationGO:00313441750.071
regulation of molecular functionGO:00650093980.069
positive regulation of neuron differentiationGO:00456661260.068
ion homeostasisGO:00508012120.068
response to peptideGO:19016522920.068
regulation of phosphorus metabolic processGO:00511743490.068
calcium ion homeostasisGO:00550741620.067
synaptic transmissionGO:00072682350.067
cellular divalent inorganic cation homeostasisGO:00725031620.065
cellular response to oxygen containing compoundGO:19017013860.063
positive regulation of multicellular organismal processGO:00512403870.063
female pregnancyGO:00075651220.062
sexual reproductionGO:00199531480.061
Mouse
regulation of hormone levelsGO:00108171870.060
blood circulationGO:00080151830.059
circulatory system processGO:00030131830.059
positive regulation of neurogenesisGO:00507691650.058
regulation of multicellular organismal developmentGO:20000263760.058
neuron developmentGO:00486662860.057
regulation of neuron projection developmentGO:00109751610.057
organelle organizationGO:00069962660.056
Mouse
neuron projection developmentGO:00311752730.056
positive regulation of developmental processGO:00510942830.055
stress activated protein kinase signaling cascadeGO:0031098370.055
regulation of signal transductionGO:00099663180.055
positive regulation of nucleobase containing compound metabolic processGO:00459353190.054
localization of cellGO:00516742020.054
cellular amino acid metabolic processGO:00065201070.054
regulation of programmed cell deathGO:00430673410.052
positive regulation of phosphate metabolic processGO:00459372620.052
regulation of protein metabolic processGO:00512462890.052
positive regulation of phosphorylationGO:00423271770.051
head developmentGO:00603222470.050
cellular component biogenesisGO:00440853680.049
cellular modified amino acid metabolic processGO:0006575610.049
gamete generationGO:00072761240.049
Mouse
response to transition metal nanoparticleGO:19902671220.048
cell cycleGO:00070491010.048
positive regulation of phosphorus metabolic processGO:00105622620.047
regulation of metal ion transportGO:00109591180.047
metal ion homeostasisGO:00550651860.047
multicellular organism reproductionGO:00325042330.047
Mouse
positive regulation of neuron projection developmentGO:0010976990.045
response to molecule of bacterial originGO:00022371940.045
peptide biosynthetic processGO:004304330.045
response to decreased oxygen levelsGO:00362932370.045
response to heatGO:0009408600.044
negative regulation of metabolic processGO:00098923310.044
positive regulation of protein modification processGO:00314011420.044
cellular chemical homeostasisGO:00550822470.044
response to hypoxiaGO:00016662310.044
positive regulation of signalingGO:00230562700.044
response to mechanical stimulusGO:00096121340.043
protein complex assemblyGO:00064612630.043
locomotionGO:00400112370.043
positive regulation of cell migrationGO:0030335960.043
purine nucleotide biosynthetic processGO:0006164830.043
cellular response to organic cyclic compoundGO:00714072020.043
response to estradiolGO:00323551640.042
cellular component movementGO:00069282480.042
negative regulation of phosphorus metabolic processGO:0010563800.042
positive regulation of cell differentiationGO:00455972170.041
eye developmentGO:0001654500.041
cellular response to growth factor stimulusGO:00713631620.041
signal transduction by phosphorylationGO:00230141440.041
anatomical structure morphogenesisGO:00096532980.041
sex differentiationGO:00075481130.041
positive regulation of biosynthetic processGO:00098913190.041
sensory organ developmentGO:0007423740.040
positive regulation of signal transductionGO:00099671750.040
norepinephrine metabolic processGO:004241530.039
negative regulation of cell proliferationGO:00082851190.039
cellular ion homeostasisGO:00068731840.039
cell motilityGO:00488702020.039
negative regulation of multicellular organismal processGO:00512412030.038
positive regulation of cellular component organizationGO:00511302000.038
negative regulation of cellular component organizationGO:0051129830.038
positive regulation of nitrogen compound metabolic processGO:00511733340.037
macromolecular complex assemblyGO:00650032730.037
response to bacteriumGO:00096172000.037
carbohydrate metabolic processGO:00059751300.037
response to axon injuryGO:0048678590.037
nucleoside phosphate biosynthetic processGO:19012931020.037
cellular component assemblyGO:00226073600.036
response to growth factorGO:00708481890.036
peptide metabolic processGO:0006518320.036
tissue developmentGO:00098882520.036
nucleotide biosynthetic processGO:0009165980.036
intracellular transportGO:00469071850.036
reproductive system developmentGO:00614581280.035
positive regulation of kinase activityGO:0033674770.035
negative regulation of cell communicationGO:00106481580.035
gliogenesisGO:0042063930.035
multi multicellular organism processGO:00447061380.035
regulation of cell motilityGO:20001451310.034
organophosphate biosynthetic processGO:00904071430.033
regulation of cell proliferationGO:00421273590.033
cellular metal ion homeostasisGO:00068751720.033
response to organophosphorusGO:00466831020.033
single organism carbohydrate metabolic processGO:00447231180.032
peptidyl amino acid modificationGO:00181931260.032
negative regulation of signalingGO:00230571570.032
positive regulation of purine nucleotide biosynthetic processGO:1900373360.032
positive regulation of nervous system developmentGO:00519621780.032
cellular response to cytokine stimulusGO:00713451270.032
embryo implantationGO:0007566150.031
positive regulation of transportGO:00510502450.031
negative regulation of cell differentiationGO:0045596990.031
pyruvate metabolic processGO:0006090270.030
cell type specific apoptotic processGO:00972851340.030
response to external biotic stimulusGO:00432072210.030
sulfur compound metabolic processGO:0006790700.030
response to ketoneGO:19016541820.030
protein complex subunit organizationGO:00718223020.030
positive regulation of cell projection organizationGO:00313461110.029
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044130.029
positive regulation of cellular protein metabolic processGO:00322701670.029
rna metabolic processGO:00160704060.029
cell migrationGO:00164771970.029
positive regulation of protein phosphorylationGO:00019341350.029
regulation of system processGO:00440572080.029
cytosolic calcium ion homeostasisGO:00514801400.029
response to vitaminGO:00332731310.029
negative regulation of protein metabolic processGO:00512481140.029
muscle contractionGO:0006936880.028
positive regulation of rna metabolic processGO:00512542030.028
single organism biosynthetic processGO:00447113420.028
positive regulation of intracellular signal transductionGO:19025331380.028
mapk cascadeGO:00001651400.028
cellular response to lipidGO:00713962010.028
negative regulation of neurogenesisGO:0050768780.027
response to purine containing compoundGO:00140741260.027
regulation of organelle organizationGO:0033043800.027
regulation of locomotionGO:00400121480.027
single organism organelle organizationGO:19025891800.027
positive regulation of protein metabolic processGO:00512471780.026
regulation of cell migrationGO:00303341280.026
regulation of mapk cascadeGO:00434081160.026
cellular ketone metabolic processGO:0042180510.026
response to antibioticGO:0046677390.026
muscle system processGO:00030121150.026
cell growthGO:00160491040.025
tube developmentGO:0035295890.025
brain renin angiotensin systemGO:000203530.025
purine ribonucleotide biosynthetic processGO:0009152810.025
drinking behaviorGO:0042756110.024
axis specificationGO:000979840.024
response to radiationGO:00093141370.024
regulation of anatomical structure sizeGO:00900661350.024
ribose phosphate biosynthetic processGO:0046390870.024
positive regulation of ion transportGO:0043270940.024
secretion by cellGO:00329402480.023
regulation of catalytic activityGO:00507903040.023
response to acid chemicalGO:00011012220.023
synaptic growth at neuromuscular junctionGO:005112410.023
cellular response to external stimulusGO:00714961180.023
cellular response to organonitrogen compoundGO:00714171970.023
carbohydrate derivative biosynthetic processGO:19011371240.023
cellular component morphogenesisGO:00329891550.022
regulation of intracellular signal transductionGO:19025312180.022
regulation of calcium ion transportGO:0051924770.022
negative regulation of programmed cell deathGO:00430691830.022
regulation of catabolic processGO:00098941130.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
response to amino acidGO:0043200750.022
regulation of response to stressGO:00801341260.022
cell adhesionGO:00071551100.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.022
defense responseGO:00069521940.022
divalent inorganic cation homeostasisGO:00725071650.021
transcription from rna polymerase ii promoterGO:00063662520.021
calcium ion transportGO:00068161310.021
pigment biosynthetic processGO:004614840.021
response to menaquinoneGO:003257210.021
cellular response to ketoneGO:1901655510.021
regulation of systemic arterial blood pressureGO:0003073300.021
feeding behaviorGO:0007631530.020
negative regulation of macromolecule metabolic processGO:00106052600.020
negative regulation of response to stimulusGO:00485851550.020
positive regulation of secretion by cellGO:19035321280.020
male sex differentiationGO:0046661640.020
nitrogen compound transportGO:00717052290.020
enzyme linked receptor protein signaling pathwayGO:00071671160.020
transcription dna templatedGO:00063513770.020
negative regulation of cellular metabolic processGO:00313242810.020
regulation of defense responseGO:0031347680.020
oxoacid metabolic processGO:00434362900.020
positive regulation of cell developmentGO:00107201760.020
cell morphogenesisGO:00009021420.020
transmembrane transportGO:00550854120.020
response to cadmium ionGO:0046686350.020
homeostatic processGO:00425923310.020
rhythmic processGO:00485111560.019
single organism cellular localizationGO:19025801020.019
maternal process involved in female pregnancyGO:0060135380.019
negative regulation of cell cycle phase transitionGO:190198840.019
protein autophosphorylationGO:0046777660.019
negative regulation of protein phosphorylationGO:0001933440.018
regulation of microtubule cytoskeleton organizationGO:0070507140.018
regulation of cellular protein metabolic processGO:00322682670.018
organic cyclic compound catabolic processGO:19013611750.018
proteolysisGO:00065081750.018
protein complex biogenesisGO:00702712630.018
cellular response to lipopolysaccharideGO:0071222550.018
nucleobase containing small molecule metabolic processGO:00550863160.018
positive regulation of cellular component movementGO:00512721020.018
positive regulation of glycolytic processGO:004582150.018
hair cycleGO:004263330.018
cell cycle processGO:0022402570.018
regulation of carbohydrate catabolic processGO:0043470140.018
regulation of synaptic plasticityGO:0048167700.018
positive regulation of cellular amine metabolic processGO:003324030.018
regulation of camp biosynthetic processGO:0030817380.018
organophosphate catabolic processGO:00464341480.017
regulation of cellular ketone metabolic processGO:0010565270.017
porphyrin containing compound metabolic processGO:000677880.017
spermatogenesisGO:0007283990.017
Mouse
neuron apoptotic processGO:0051402880.017
regulation of cellular catabolic processGO:00313291010.017
regulation of cell cycleGO:0051726730.017
purine containing compound biosynthetic processGO:0072522850.017
regulation of protein kinase activityGO:00458591050.017
regulation of response to external stimulusGO:00321011060.017
cytoplasmic transportGO:00164821150.017
organic anion transportGO:00157111320.017
multicellular organismal homeostasisGO:0048871490.017
regulation of glycolytic processGO:000611070.016
growthGO:00400071650.016
immune system processGO:00023762040.016
positive regulation of locomotionGO:00400171020.016
positive regulation of cell proliferationGO:00082842490.016
amine metabolic processGO:0009308380.016
porphyrin containing compound biosynthetic processGO:000677960.016
carboxylic acid transportGO:00469421150.016
macromolecule localizationGO:00330362520.016
response to lipopolysaccharideGO:00324961910.016
cellular response to hormone stimulusGO:00328702470.016
dna metabolic processGO:0006259960.016
protein localizationGO:00081041910.016
regulation of neurotransmitter levelsGO:0001505420.016
cofactor biosynthetic processGO:0051188280.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
macromolecule catabolic processGO:0009057580.015
negative regulation of cell developmentGO:0010721820.015
synaptic vesicle transportGO:0048489230.015
regulation of cellular localizationGO:00603412630.015
mitotic cell cycleGO:0000278490.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
forebrain developmentGO:0030900980.015
protein transportGO:00150311320.015
molting cycle processGO:002240420.015
regulation of cellular amino acid metabolic processGO:000652120.015
heme biosynthetic processGO:000678340.015
regulation of apoptotic processGO:00429813350.015
nucleoside phosphate metabolic processGO:00067532830.015
positive regulation of cell motilityGO:2000147970.015
fibroblast growth factor receptor signaling pathwayGO:000854380.015
cellular response to hydrogen peroxideGO:0070301420.015
development of primary sexual characteristicsGO:00451371070.015
response to oxygen levelsGO:00704822650.015
response to ammonium ionGO:0060359710.015
organic hydroxy compound metabolic processGO:19016151150.014
response to alkaloidGO:00432791320.014
negative regulation of secretionGO:0051048820.014
pteridine containing compound metabolic processGO:0042558140.014
response to insulinGO:00328681330.014
regulation of dna metabolic processGO:0051052600.014
response to aluminum ionGO:0010044100.014
ribose phosphate metabolic processGO:00196932350.014
telencephalon developmentGO:0021537620.014
cellular response to metal ionGO:0071248550.014
negative regulation of catalytic activityGO:00430861030.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
carbohydrate derivative metabolic processGO:19011353460.014
hormone metabolic processGO:0042445690.014
necroptotic processGO:007026620.014
reactive nitrogen species metabolic processGO:200105710.014
sorbitol biosynthetic processGO:000606110.014
regulation of muscle contractionGO:0006937530.014
organic acid transportGO:00158491160.013
positive regulation of synaptic transmissionGO:0050806620.013
positive regulation of camp mediated signalingGO:004395020.013
apoptotic signaling pathwayGO:0097190270.013
nucleoside metabolic processGO:00091161790.013
embryo developmentGO:0009790490.013
divalent metal ion transportGO:00708381320.013
mitotic spindle organizationGO:000705220.013
small gtpase mediated signal transductionGO:0007264360.013
monocarboxylic acid metabolic processGO:00327871520.013
negative regulation of mapk cascadeGO:0043409200.013
negative regulation of apoptotic processGO:00430661810.013
negative regulation of signal transductionGO:0009968830.013
response to starvationGO:0042594590.013
male gamete generationGO:0048232990.013
Mouse
vascular process in circulatory systemGO:0003018960.013
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
negative regulation of cellular protein metabolic processGO:00322691060.012
anion transportGO:00068201780.012
cellular response to extracellular stimulusGO:0031668730.012
hair follicle developmentGO:000194220.012
regulation of nucleotide metabolic processGO:00061401170.012
neuron deathGO:00709971270.012
cofactor metabolic processGO:0051186950.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
macroautophagyGO:001623640.012
regulation of purine nucleotide biosynthetic processGO:1900371460.012
positive regulation of molecular functionGO:00440932300.012
positive regulation of gene expressionGO:00106282440.012
regulation of necroptotic processGO:006054420.012
positive regulation of immune responseGO:0050778420.012
response to mercury ionGO:0046689150.012
heart morphogenesisGO:000300730.012
immune responseGO:00069551040.012
glial cell differentiationGO:0010001650.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
defense response to gram negative bacteriumGO:005082930.012
fatty acid metabolic processGO:0006631990.012
glycosyl compound metabolic processGO:19016571820.012
negative regulation of molecular functionGO:00440921330.011
response to electrical stimulusGO:0051602560.011
hair cycle processGO:002240520.011
positive regulation of organelle organizationGO:0010638480.011
sensory perceptionGO:00076001010.011
microtubule based processGO:0007017360.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
chemical homeostasisGO:00488782920.011
neurological system processGO:00508772190.011
microtubule cytoskeleton organizationGO:0000226250.011
secretionGO:00469033070.011
positive regulation of catalytic activityGO:00430851840.011
regulation of response to woundingGO:1903034690.011
epithelium developmentGO:0060429960.011
action potentialGO:0001508540.011
positive regulation of transferase activityGO:0051347810.011
cellular macromolecule localizationGO:00707271220.011
cellular homeostasisGO:00197252520.011
regulation of smooth muscle cell migrationGO:0014910360.011
defense response to gram positive bacteriumGO:005083020.011
protein oligomerizationGO:00512591910.011
regulation of cellular amine metabolic processGO:003323880.011
negative regulation of protein modification processGO:0031400520.011
cellular response to drugGO:0035690300.011
synaptic vesicle endocytosisGO:004848840.011
cellular response to hypoxiaGO:0071456510.011
limbic system developmentGO:0021761380.011
dna integrity checkpointGO:003157020.010
regulation of transcription dna templatedGO:00063553740.010
response to interleukin 1GO:0070555550.010
adult locomotory behaviorGO:000834440.010
axon developmentGO:0061564960.010
cellular response to abiotic stimulusGO:0071214850.010
molting cycleGO:004230330.010
camp biosynthetic processGO:0006171470.010
anterior posterior pattern specificationGO:000995210.010
embryonic pattern specificationGO:000988010.010
cyclic nucleotide biosynthetic processGO:0009190630.010
membrane organizationGO:0061024940.010
cellular response to inorganic substanceGO:0071241650.010
positive regulation of smooth muscle cell migrationGO:0014911270.010
regulation of anatomical structure morphogenesisGO:00226031410.010
negative regulation of transportGO:00510511360.010
monosaccharide metabolic processGO:0005996610.010

Gpx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011