Rattus norvegicus

35 known processes

Sbk1

SH3-binding domain kinase 1

(Aliases: Sbk)

Sbk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.485
growthGO:00400071650.406
regulation of nucleic acid templated transcriptionGO:19035063800.400
rna biosynthetic processGO:00327743800.351
nucleic acid templated transcriptionGO:00976593790.341
transcription from rna polymerase ii promoterGO:00063662520.285
regulation of transcription dna templatedGO:00063553740.261
regulation of rna biosynthetic processGO:20011413810.248
response to corticosteroidGO:00319602350.245
cellular response to stressGO:00335542690.215
positive regulation of gene expressionGO:00106282440.196
regulation of transcription from rna polymerase ii promoterGO:00063572340.160
cellular response to peptideGO:19016531330.159
positive regulation of rna metabolic processGO:00512542030.155
regulation of rna metabolic processGO:00512523910.155
rna metabolic processGO:00160704060.153
positive regulation of nucleobase containing compound metabolic processGO:00459353190.150
axon developmentGO:0061564960.146
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.145
response to starvationGO:0042594590.142
positive regulation of nucleic acid templated transcriptionGO:19035081970.141
regulation of apoptotic processGO:00429813350.140
positive regulation of rna biosynthetic processGO:19026801970.139
single organism organelle organizationGO:19025891800.137
negative regulation of apoptotic processGO:00430661810.126
positive regulation of macromolecule biosynthetic processGO:00105572470.121
intracellular signal transductionGO:00355563140.120
programmed cell deathGO:00125013920.112
positive regulation of cellular biosynthetic processGO:00313282950.109
glial cell differentiationGO:0010001650.108
organelle organizationGO:00069962660.106
response to peptide hormoneGO:00434342780.104
positive regulation of cell differentiationGO:00455972170.100
regulation of catalytic activityGO:00507903040.095
purine nucleoside metabolic processGO:00422781690.095
cellular catabolic processGO:00442482950.094
negative regulation of cellular component organizationGO:0051129830.093
regulation of lipid metabolic processGO:0019216680.093
sensory organ developmentGO:0007423740.090
single organism catabolic processGO:00447122830.088
anion transportGO:00068201780.086
positive regulation of biosynthetic processGO:00098913190.086
positive regulation of transcription dna templatedGO:00458931970.086
regulation of programmed cell deathGO:00430673410.085
apoptotic processGO:00069153810.084
central nervous system developmentGO:00074173110.084
anatomical structure morphogenesisGO:00096532980.082
positive regulation of nitrogen compound metabolic processGO:00511733340.081
cell cell signalingGO:00072673350.079
membrane organizationGO:0061024940.077
purine nucleotide metabolic processGO:00061632290.076
gland developmentGO:00487321550.076
regulation of protein modification processGO:00313991940.076
negative regulation of metabolic processGO:00098923310.075
response to oxygen levelsGO:00704822650.074
response to extracellular stimulusGO:00099913800.074
negative regulation of signalingGO:00230571570.074
ribose phosphate metabolic processGO:00196932350.072
carbohydrate metabolic processGO:00059751300.071
regulation of cell cycleGO:0051726730.071
digestive system developmentGO:0055123410.070
regulation of protein metabolic processGO:00512462890.070
cellular response to insulin stimulusGO:0032869810.069
regulation of phosphorus metabolic processGO:00511743490.069
response to hypoxiaGO:00016662310.068
organic acid metabolic processGO:00060822920.068
positive regulation of nervous system developmentGO:00519621780.067
response to heatGO:0009408600.067
negative regulation of signal transductionGO:0009968830.066
regulation of cellular protein metabolic processGO:00322682670.065
oxidation reduction processGO:00551143040.064
positive regulation of cell communicationGO:00106472710.064
response to estrogenGO:00436272320.063
positive regulation of response to stimulusGO:00485842850.063
gliogenesisGO:0042063930.062
response to inorganic substanceGO:00100353770.062
reproductionGO:00000032450.059
reproductive structure developmentGO:00486081280.058
carbohydrate derivative metabolic processGO:19011353460.057
nucleocytoplasmic transportGO:0006913480.057
cellular response to peptide hormone stimulusGO:00713751200.056
establishment of protein localization to organelleGO:0072594440.056
cellular ketone metabolic processGO:0042180510.056
positive regulation of multicellular organismal processGO:00512403870.056
neuron deathGO:00709971270.055
positive regulation of signal transductionGO:00099671750.055
nucleobase containing small molecule metabolic processGO:00550863160.054
negative regulation of macromolecule metabolic processGO:00106052600.054
protein autophosphorylationGO:0046777660.054
epithelium developmentGO:0060429960.053
response to metal ionGO:00100382530.053
negative regulation of cell deathGO:00605482290.053
developmental growthGO:00485891000.053
brain developmentGO:00074202470.053
ribonucleotide metabolic processGO:00092592310.053
gastrulationGO:000736920.051
cellular response to hormone stimulusGO:00328702470.051
regulation of intracellular signal transductionGO:19025312180.051
response to nutrient levelsGO:00316673700.051
regulation of phosphate metabolic processGO:00192203490.051
regulation of cellular response to stressGO:0080135490.051
cellular response to oxygen containing compoundGO:19017013860.050
intracellular transportGO:00469071850.050
multicellular organism growthGO:003526410.050
regulation of signal transductionGO:00099663180.050
multicellular organism reproductionGO:00325042330.050
neuron differentiationGO:00301823680.049
cell type specific apoptotic processGO:00972851340.049
positive regulation of programmed cell deathGO:00430681570.049
response to peptideGO:19016522920.048
protein phosphorylationGO:00064683450.048
heart developmentGO:0007507720.048
single organism intracellular transportGO:19025821660.048
head developmentGO:00603222470.048
response to carbohydrateGO:00097431830.047
action potentialGO:0001508540.047
positive regulation of neurogenesisGO:00507691650.047
ribonucleoside metabolic processGO:00091191740.047
single organism carbohydrate metabolic processGO:00447231180.046
response to decreased oxygen levelsGO:00362932370.045
lipid metabolic processGO:00066292830.045
regulation of phosphorylationGO:00423252480.045
regulation of transferase activityGO:00513381230.045
positive regulation of developmental processGO:00510942830.045
reproductive processGO:00224143720.045
regulation of cell differentiationGO:00455953200.045
negative regulation of cellular metabolic processGO:00313242810.044
tissue developmentGO:00098882520.044
multicellular organismal reproductive processGO:00486092330.044
negative regulation of cell communicationGO:00106481580.044
amine metabolic processGO:0009308380.044
regulation of molecular functionGO:00650093980.044
purine ribonucleotide metabolic processGO:00091502270.044
regulation of nucleotide metabolic processGO:00061401170.043
cellular amino acid metabolic processGO:00065201070.042
mapk cascadeGO:00001651400.042
peptidyl tyrosine modificationGO:0018212720.042
regulation of cellular amino acid metabolic processGO:000652120.039
purine containing compound metabolic processGO:00725212530.039
positive regulation of apoptotic processGO:00430651540.038
nuclear transportGO:0051169490.038
regulation of cellular ketone metabolic processGO:0010565270.038
maintenance of locationGO:0051235170.038
negative regulation of biosynthetic processGO:00098901680.038
oxoacid metabolic processGO:00434362900.038
positive regulation of cellular protein metabolic processGO:00322701670.038
regulation of cell proliferationGO:00421273590.037
single organism nuclear importGO:1902593350.037
b cell differentiationGO:003018320.037
regulation of map kinase activityGO:0043405530.037
cellular response to organonitrogen compoundGO:00714171970.037
cellular lipid metabolic processGO:00442552080.037
tube developmentGO:0035295890.036
regulation of cell motilityGO:20001451310.036
signal transduction by phosphorylationGO:00230141440.036
peptidyl amino acid modificationGO:00181931260.035
cellular component morphogenesisGO:00329891550.035
cardiac chamber developmentGO:000320510.035
hexose metabolic processGO:0019318580.035
cell morphogenesis involved in neuron differentiationGO:00486671060.035
organophosphate metabolic processGO:00196373700.035
response to cytokineGO:00340972150.035
cellular component biogenesisGO:00440853680.035
microvillus assemblyGO:003003320.034
negative regulation of gene expressionGO:00106291990.034
ensheathment of neuronsGO:0007272400.033
cellular protein localizationGO:00346131220.033
single organism reproductive processGO:00447022970.033
single organism biosynthetic processGO:00447113420.033
positive regulation of cellular component organizationGO:00511302000.033
neurological system processGO:00508772190.033
negative regulation of protein metabolic processGO:00512481140.032
regulation of growthGO:00400081050.032
response to alkaloidGO:00432791320.032
cellular component assemblyGO:00226073600.032
negative regulation of phosphorus metabolic processGO:0010563800.032
negative regulation of heart growthGO:006111730.032
negative regulation of nitrogen compound metabolic processGO:00511721610.032
regenerationGO:00310991630.031
neuron apoptotic processGO:0051402880.031
regulation of cell morphogenesisGO:0022604770.031
negative regulation of nucleobase containing compound metabolic processGO:00459341530.031
response to oxidative stressGO:00069791860.031
regulation of mapk cascadeGO:00434081160.031
cellular response to nitrogen compoundGO:19016992100.031
peptidyl tyrosine phosphorylationGO:0018108720.031
organic substance catabolic processGO:19015753160.030
regulation of nucleocytoplasmic transportGO:0046822280.030
positive regulation of signalingGO:00230562700.030
regulation of membrane potentialGO:00423911100.030
agingGO:00075682410.030
catabolic processGO:00090563510.030
cellular amine metabolic processGO:0044106380.029
reproductive system developmentGO:00614581280.029
localization of cellGO:00516742020.029
multicellular organismal signalingGO:0035637440.029
actin cytoskeleton organizationGO:0030036730.029
nucleoside phosphate metabolic processGO:00067532830.029
regulation of neuron apoptotic processGO:0043523830.029
protein importGO:0017038370.029
protein import into nucleusGO:0006606350.029
glycerolipid metabolic processGO:0046486670.029
negative regulation of response to stimulusGO:00485851550.029
lipid storageGO:001991510.028
anterior posterior pattern specificationGO:000995210.028
neuron projection developmentGO:00311752730.028
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.028
macromolecule localizationGO:00330362520.028
actin filament based processGO:0030029860.027
negative regulation of programmed cell deathGO:00430691830.027
axon ensheathmentGO:0008366400.027
organ regenerationGO:00311001010.027
response to ethanolGO:00454711620.027
gland morphogenesisGO:0022612120.027
positive regulation of cell proliferationGO:00082842490.027
cell matrix adhesionGO:0007160190.026
nucleotide metabolic processGO:00091172790.026
response to campGO:0051591910.026
response to glucocorticoidGO:00513842230.026
reactive oxygen species metabolic processGO:0072593370.026
regulation of protein phosphorylationGO:00019321830.025
muscle structure developmentGO:0061061870.025
protein targeting to nucleusGO:0044744350.025
regulation of neurogenesisGO:00507672470.025
positive regulation of nucleoside metabolic processGO:0045979550.024
regulation of cell growthGO:0001558850.024
glycosyl compound metabolic processGO:19016571820.024
regulation of protein kinase activityGO:00458591050.024
stem cell differentiationGO:0048863160.024
response to insulinGO:00328681330.024
negative regulation of cellular protein metabolic processGO:00322691060.024
cellular response to abiotic stimulusGO:0071214850.024
positive regulation of phosphorylationGO:00423271770.024
regulation of cell developmentGO:00602842630.024
stress activated mapk cascadeGO:0051403350.024
enzyme linked receptor protein signaling pathwayGO:00071671160.024
negative regulation of cellular biosynthetic processGO:00313271610.024
cell cycle checkpointGO:000007520.023
nucleobase containing compound catabolic processGO:00346551520.023
positive regulation of catalytic activityGO:00430851840.023
positive regulation of mitochondrion organizationGO:001082240.023
cell cycleGO:00070491010.023
positive regulation of protein modification processGO:00314011420.023
sexual reproductionGO:00199531480.023
negative regulation of mitotic cell cycle phase transitionGO:190199130.023
sex differentiationGO:00075481130.022
multi organism reproductive processGO:00447032620.022
heart morphogenesisGO:000300730.022
cellular response to extracellular stimulusGO:0031668730.022
cell projection organizationGO:00300303020.022
organ morphogenesisGO:0009887750.022
positive regulation of cell developmentGO:00107201760.022
transmission of nerve impulseGO:0019226420.022
cytoplasmic transportGO:00164821150.022
developmental process involved in reproductionGO:00030061590.022
regulation of kinase activityGO:00435491170.022
spinal cord developmentGO:0021510270.022
negative regulation of phosphate metabolic processGO:0045936800.022
regulation of neuron deathGO:19012141150.022
negative regulation of metanephros developmentGO:007221720.021
regulation of bmp signaling pathwayGO:003051020.021
cell growthGO:00160491040.021
negative regulation of protein phosphorylationGO:0001933440.021
protein oligomerizationGO:00512591910.021
negative regulation of neuron apoptotic processGO:0043524450.021
cellular carbohydrate metabolic processGO:0044262720.021
regulation of cellular component biogenesisGO:0044087860.021
cellular macromolecule localizationGO:00707271220.021
positive regulation of growthGO:0045927550.020
regulation of sequence specific dna binding transcription factor activityGO:0051090350.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
intracellular receptor signaling pathwayGO:0030522350.020
cell communication involved in cardiac conductionGO:008606520.020
regulation of cellular localizationGO:00603412630.020
ribonucleotide catabolic processGO:00092611360.020
regulation of multicellular organismal developmentGO:20000263760.020
protein modification by small protein conjugation or removalGO:0070647350.020
insulin secretionGO:0030073690.020
carboxylic acid metabolic processGO:00197522890.020
heterocycle catabolic processGO:00467001670.020
gamete generationGO:00072761240.020
positive regulation of neuron differentiationGO:00456661260.020
monosaccharide metabolic processGO:0005996610.020
macromolecular complex subunit organizationGO:00439333390.020
neuronal action potentialGO:0019228350.020
nuclear importGO:0051170350.020
organonitrogen compound catabolic processGO:19015651790.020
response to transition metal nanoparticleGO:19902671220.019
male sex differentiationGO:0046661640.019
regulation of g2 m transition of mitotic cell cycleGO:001038940.019
chemosensory behaviorGO:000763520.019
establishment of organelle localizationGO:0051656370.019
regulation of cell projection organizationGO:00313441750.019
positive regulation of cell deathGO:00109421840.019
activation of protein kinase b activityGO:003214830.019
purine nucleoside monophosphate biosynthetic processGO:0009127200.019
regulation of cellular amine metabolic processGO:003323880.019
myelinationGO:0042552390.019
hematopoietic or lymphoid organ developmentGO:0048534360.019
response to temperature stimulusGO:0009266940.019
positive regulation of protein metabolic processGO:00512471780.019
cellular component movementGO:00069282480.019
positive regulation of phosphorus metabolic processGO:00105622620.019
rhythmic processGO:00485111560.019
cellular response to endogenous stimulusGO:00714953770.019
negative regulation of transportGO:00510511360.019
carbohydrate derivative catabolic processGO:19011361470.018
regulation of hydrolase activityGO:00513361430.018
single organism membrane organizationGO:0044802740.018
regulation of nervous system developmentGO:00519602640.018
protein tetramerizationGO:0051262380.018
regulation of dna metabolic processGO:0051052600.018
synaptic growth at neuromuscular junctionGO:005112410.018
glucose metabolic processGO:0006006520.018
cellular nitrogen compound catabolic processGO:00442701630.018
telencephalon developmentGO:0021537620.018
cytoskeleton organizationGO:00070101110.018
response to external biotic stimulusGO:00432072210.018
regulation of cellular carbohydrate metabolic processGO:0010675390.018
purine nucleoside triphosphate metabolic processGO:00091441410.018
response to reactive oxygen speciesGO:00003021200.018
hematopoietic progenitor cell differentiationGO:000224420.018
mesoderm developmentGO:000749820.017
negative regulation of rna metabolic processGO:00512531230.017
protein localizationGO:00081041910.017
spindle organizationGO:000705120.017
negative regulation of developmental processGO:00510931250.017
intracellular protein transportGO:0006886790.017
proteolysisGO:00065081750.017
positive regulation of cell projection organizationGO:00313461110.017
negative regulation of multicellular organismal processGO:00512412030.017
negative regulation of transcription dna templatedGO:00458921160.017
t cell homeostasisGO:004302920.017
negative regulation of rna biosynthetic processGO:19026791180.017
salivary gland developmentGO:000743130.017
macroautophagyGO:001623640.017
purine ribonucleoside metabolic processGO:00461281680.017
energy derivation by oxidation of organic compoundsGO:0015980460.017
regulation of catabolic processGO:00098941130.017
negative regulation of mapk cascadeGO:0043409200.017
cellular response to oxygen levelsGO:0071453600.016
protein targetingGO:0006605610.016
negative regulation of neuron deathGO:1901215690.016
dna metabolic processGO:0006259960.016
lymphoid progenitor cell differentiationGO:000232020.016
negative regulation of cell cycle phase transitionGO:190198840.016
protein localization to nucleusGO:0034504390.016
negative regulation of phosphorylationGO:0042326570.016
inorganic ion transmembrane transportGO:00986602290.016
response to axon injuryGO:0048678590.016
monocarboxylic acid metabolic processGO:00327871520.016
regulation of response to stressGO:00801341260.016
cell morphogenesisGO:00009021420.016
aromatic compound catabolic processGO:00194391680.016
dephosphorylationGO:0016311980.016
protein modification by small protein conjugationGO:0032446310.015
cell part morphogenesisGO:00329901230.015
organelle localizationGO:0051640550.015
cell motilityGO:00488702020.015
negative regulation of molecular functionGO:00440921330.015
cell adhesionGO:00071551100.015
embryonic pattern specificationGO:000988010.015
homeostatic processGO:00425923310.015
regulation of locomotionGO:00400121480.015
gonad developmentGO:00084061040.015
cellular response to oxidative stressGO:0034599760.015
response to bacteriumGO:00096172000.015
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
regulation of cellular component organizationGO:00511283680.015
immune effector processGO:0002252530.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
cellular response to vitamin eGO:007130630.015
cell migrationGO:00164771970.015
sulfur compound metabolic processGO:0006790700.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
detection of calcium ionGO:000551310.015
response to growth factorGO:00708481890.015
developmental maturationGO:0021700250.015
thyroid gland developmentGO:003087810.015
nucleoside metabolic processGO:00091161790.015
cytokine mediated signaling pathwayGO:0019221430.015
nucleotide catabolic processGO:00091661390.015
formation of primary germ layerGO:000170410.014
negative regulation of transferase activityGO:0051348290.014
regulation of cellular component movementGO:00512701500.014
response to ammonium ionGO:0060359710.014
lymphocyte homeostasisGO:000226020.014
circadian rhythmGO:0007623880.014
immune system developmentGO:0002520410.014
positive regulation of cellular amine metabolic processGO:003324030.014
positive regulation of molecular functionGO:00440932300.014
cellular response to cytokine stimulusGO:00713451270.014
detection of chemical stimulusGO:0009593100.014
organic cyclic compound catabolic processGO:19013611750.014
cellular response to corticosteroid stimulusGO:0071384690.014
response to nutrientGO:00075842480.014
muscle system processGO:00030121150.014
phosphatidylinositol dephosphorylationGO:004685640.014
regulation of vesicle mediated transportGO:0060627810.014
cellular response to external stimulusGO:00714961180.014
epithelial cell differentiationGO:0030855710.014
immune system processGO:00023762040.014
lymphocyte activationGO:0046649430.014
hair cell differentiationGO:003531520.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
positive regulation of mapk cascadeGO:0043410920.014
endocardial cushion developmentGO:000319710.014
negative regulation of nervous system developmentGO:0051961790.014
mitotic spindle organizationGO:000705220.014
negative regulation of collateral sproutingGO:004867120.014
regulation of mitotic sister chromatid separationGO:001096510.014
glycosyl compound catabolic processGO:19016581260.013
positive regulation of intracellular signal transductionGO:19025331380.013
embryo developmentGO:0009790490.013
regulation of metanephros developmentGO:007221540.013
negative regulation of intracellular signal transductionGO:1902532380.013
response to acid chemicalGO:00011012220.013
cellular response to starvationGO:0009267270.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
palate developmentGO:006002120.013
insulin receptor signaling pathwayGO:0008286240.013
dendrite developmentGO:0016358720.013
male gonad developmentGO:0008584590.013
tissue regenerationGO:0042246360.013
forebrain developmentGO:0030900980.013
development of primary male sexual characteristicsGO:0046546590.013
circulatory system developmentGO:00723591340.013
response to amineGO:0014075460.013
regulation of protein serine threonine kinase activityGO:0071900640.013
hair follicle developmentGO:000194220.013
response to light stimulusGO:0009416520.013
response to vitaminGO:00332731310.013
leukocyte activationGO:0045321760.013
development of primary sexual characteristicsGO:00451371070.013
regulation of protein targetingGO:1903533280.013
cell cycle processGO:0022402570.013
negative regulation of catalytic activityGO:00430861030.012
regulation of phosphatidylinositol dephosphorylationGO:006030410.012
purine nucleotide catabolic processGO:00061951360.012
negative regulation of protein modification processGO:0031400520.012
response to ketoneGO:19016541820.012
response to biotic stimulusGO:00096072260.012
regulation of hormone levelsGO:00108171870.012
secretionGO:00469033070.012
metal ion transportGO:00300012890.012
negative regulation of growthGO:0045926370.012
digestive tract developmentGO:0048565390.012
negative regulation of cell differentiationGO:0045596990.012
regulation of protein maturationGO:1903317500.012
hexose transportGO:0008645290.012
regulation of immune system processGO:00026821230.012
organ formationGO:004864530.012
regulation of cellular catabolic processGO:00313291010.012
negative regulation of cell developmentGO:0010721820.012
mitotic sister chromatid separationGO:005130610.012
regulation of carbohydrate metabolic processGO:0006109410.012
cation transportGO:00068123820.012
vesicle localizationGO:0051648330.012
cell differentiation involved in kidney developmentGO:006100540.012
activation of protein kinase activityGO:0032147470.012
regulation of developmental growthGO:0048638450.012
response to glucoseGO:00097491360.012
regulation of purine nucleotide metabolic processGO:19005421150.012
defecationGO:003042110.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
regulation of epithelial to mesenchymal transitionGO:001071720.012
purine ribonucleotide catabolic processGO:00091541360.012
neuromuscular synaptic transmissionGO:000727420.012
behavioral response to ethanolGO:004814910.012
regulation of microvillus organizationGO:003253010.012
behaviorGO:00076102050.012
positive regulation of map kinase activityGO:0043406460.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
carbohydrate biosynthetic processGO:0016051420.012
vesicle mediated transportGO:00161921810.011
negative regulation of secretion by cellGO:1903531720.011
erythrocyte differentiationGO:003021810.011
regulation of immune responseGO:0050776550.011
response to dexamethasoneGO:0071548490.011
ion transmembrane transportGO:00342203650.011
regulation of insulin secretionGO:0050796650.011
regulation of defecationGO:200029210.011
olfactory learningGO:000835510.011
nucleoside triphosphate metabolic processGO:00091411440.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
female sex differentiationGO:0046660590.011
protein complex assemblyGO:00064612630.011
positive regulation of neuron projection developmentGO:0010976990.011
response to other organismGO:00517072200.011

Sbk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.037
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
central nervous system diseaseDOID:33100.019