Rattus norvegicus

33 known processes

Pdhb

pyruvate dehydrogenase (lipoamide) beta

(Aliases: MGC94149)

Pdhb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
acetyl coa biosynthetic process from pyruvateGO:000608650.747
atp synthesis coupled electron transportGO:004277320.714
sulfur compound biosynthetic processGO:0044272190.638
oxidative phosphorylationGO:000611940.570
purine ribonucleoside triphosphate metabolic processGO:00092051400.437
glycosyl compound metabolic processGO:19016571820.353
hydrogen peroxide metabolic processGO:0042743130.330
electron transport chainGO:002290050.316
single organism biosynthetic processGO:00447113420.288
oxidation reduction processGO:00551143040.267
organic acid metabolic processGO:00060822920.256
acyl coa biosynthetic processGO:007161670.219
cofactor biosynthetic processGO:0051188280.213
ribonucleoside triphosphate metabolic processGO:00091991410.200
pyruvate metabolic processGO:0006090270.189
atp metabolic processGO:0046034720.187
thioester metabolic processGO:0035383280.187
nucleoside monophosphate metabolic processGO:0009123930.184
organophosphate metabolic processGO:00196373700.181
energy derivation by oxidation of organic compoundsGO:0015980460.176
mitochondrial atp synthesis coupled electron transportGO:004277520.176
generation of precursor metabolites and energyGO:0006091620.146
purine nucleoside triphosphate metabolic processGO:00091441410.124
ribonucleoside metabolic processGO:00091191740.123
purine ribonucleotide metabolic processGO:00091502270.123
dicarboxylic acid metabolic processGO:0043648420.118
purine nucleotide metabolic processGO:00061632290.116
purine containing compound metabolic processGO:00725212530.116
cellular glucan metabolic processGO:0006073230.113
carboxylic acid metabolic processGO:00197522890.113
nucleoside phosphate metabolic processGO:00067532830.106
nucleobase containing small molecule metabolic processGO:00550863160.099
nucleotide metabolic processGO:00091172790.097
carbohydrate derivative metabolic processGO:19011353460.096
ribonucleoside monophosphate metabolic processGO:0009161880.087
purine nucleoside metabolic processGO:00422781690.087
coenzyme biosynthetic processGO:0009108220.080
oxoacid metabolic processGO:00434362900.077
nucleoside triphosphate metabolic processGO:00091411440.077
purine ribonucleoside monophosphate metabolic processGO:0009167840.068
ribonucleotide metabolic processGO:00092592310.068
purine ribonucleoside metabolic processGO:00461281680.063
coenzyme metabolic processGO:0006732860.063
purine nucleoside monophosphate metabolic processGO:0009126840.056
acyl coa metabolic processGO:0006637280.055
dephosphorylationGO:0016311980.055
ribose phosphate metabolic processGO:00196932350.048
cellular respirationGO:0045333210.047
glycogen metabolic processGO:0005977230.045
aerobic respirationGO:0009060130.044
single organism catabolic processGO:00447122830.041
polysaccharide metabolic processGO:0005976250.041
nucleoside metabolic processGO:00091161790.041
regulation of proteasomal protein catabolic processGO:006113640.039
response to nutrientGO:00075842480.037
sulfur compound metabolic processGO:0006790700.034
negative regulation of hydrogen peroxide biosynthetic processGO:001073020.033
malate metabolic processGO:000610850.032
response to nutrient levelsGO:00316673700.032
ion transmembrane transportGO:00342203650.031
oxidoreduction coenzyme metabolic processGO:0006733310.029
response to oxidative stressGO:00069791860.027
catabolic processGO:00090563510.027
regulation of apoptotic processGO:00429813350.026
regulation of catabolic processGO:00098941130.026
apoptotic processGO:00069153810.025
response to extracellular stimulusGO:00099913800.025
transmembrane transportGO:00550854120.024
nitrogen compound transportGO:00717052290.024
programmed cell deathGO:00125013920.023
reactive oxygen species metabolic processGO:0072593370.022
cellular catabolic processGO:00442482950.022
negative regulation of metabolic processGO:00098923310.022
cellular ketone metabolic processGO:0042180510.022
regulation of transcription dna templatedGO:00063553740.021
organic substance catabolic processGO:19015753160.021
chemosensory behaviorGO:000763520.021
aromatic compound catabolic processGO:00194391680.021
tricarboxylic acid cycleGO:0006099110.021
regulation of cell proliferationGO:00421273590.021
sleepGO:0030431300.020
regulation of programmed cell deathGO:00430673410.020
purine nucleoside biosynthetic processGO:0042451210.019
negative regulation of cellular metabolic processGO:00313242810.018
regulation of peptide transportGO:0090087870.018
regulation of protein metabolic processGO:00512462890.018
protein complex subunit organizationGO:00718223020.018
Fly
cellular amine metabolic processGO:0044106380.017
nucleoside phosphate catabolic processGO:19012921400.017
organic cyclic compound catabolic processGO:19013611750.017
regulation of molecular functionGO:00650093980.017
lipid biosynthetic processGO:00086101280.017
spindle organizationGO:000705120.017
regulation of phosphate metabolic processGO:00192203490.017
intracellular transportGO:00469071850.017
energy reserve metabolic processGO:0006112250.016
meiotic cell cycle processGO:190304630.016
positive regulation of protein metabolic processGO:00512471780.016
negative regulation of hydrogen peroxide metabolic processGO:001072720.016
negative regulation of chromosome organizationGO:200125110.016
response to external biotic stimulusGO:00432072210.016
anatomical structure morphogenesisGO:00096532980.016
regulation of intracellular signal transductionGO:19025312180.015
positive regulation of cell proliferationGO:00082842490.015
protein localization to chromosome centromeric regionGO:007145910.015
cellular polysaccharide metabolic processGO:0044264230.015
organelle organizationGO:00069962660.015
Fly
regulation of catalytic activityGO:00507903040.015
regulation of hydrogen peroxide metabolic processGO:001031030.014
anion transportGO:00068201780.014
multi organism reproductive processGO:00447032620.014
sexual reproductionGO:00199531480.014
neuron developmentGO:00486662860.014
protein localizationGO:00081041910.014
lipid storageGO:001991510.014
progesterone biosynthetic processGO:000670130.014
regulation of apoptotic signaling pathwayGO:2001233130.014
response to other organismGO:00517072200.014
regulation of cellular amino acid metabolic processGO:000652120.013
regulation of peptide secretionGO:0002791820.013
ras protein signal transductionGO:0007265290.013
negative regulation of macromolecule metabolic processGO:00106052600.013
central nervous system developmentGO:00074173110.013
negative regulation of gene expressionGO:00106291990.013
cellular amino acid metabolic processGO:00065201070.013
postsynaptic density protein 95 clusteringGO:009711920.013
cell projection morphogenesisGO:00488581230.013
glycosyl compound catabolic processGO:19016581260.013
macroautophagyGO:001623640.013
negative regulation of protein modification by small protein conjugation or removalGO:190332140.012
negative regulation of cellular component organizationGO:0051129830.012
organonitrogen compound catabolic processGO:19015651790.012
organophosphate biosynthetic processGO:00904071430.012
epithelium developmentGO:0060429960.012
proteolysisGO:00065081750.012
alpha amino acid metabolic processGO:1901605710.012
anterior posterior pattern specificationGO:000995210.012
pyridine containing compound metabolic processGO:0072524320.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
amine metabolic processGO:0009308380.012
response to activityGO:0014823730.012
positive regulation of peptide hormone secretionGO:0090277500.012
metaphase anaphase transition of cell cycleGO:004478410.012
peptide hormone secretionGO:0030072840.012
single organism reproductive processGO:00447022970.012
cell redox homeostasisGO:004545410.011
mitotic spindle organizationGO:000705220.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cellular macromolecule localizationGO:00707271220.011
maintenance of locationGO:0051235170.011
cellular carbohydrate metabolic processGO:0044262720.011
multicellular organism reproductionGO:00325042330.011
macromolecule localizationGO:00330362520.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
negative regulation of protein maturationGO:1903318470.011
positive regulation of transportGO:00510502450.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.010
cilium morphogenesisGO:006027120.010
regulation of cellular component organizationGO:00511283680.010
brain developmentGO:00074202470.010
regulation of cellular localizationGO:00603412630.010
neuron projection morphogenesisGO:00488121220.010
homeostatic processGO:00425923310.010
purine nucleobase metabolic processGO:000614440.010
positive regulation of nitrogen compound metabolic processGO:00511733340.010
pyridine nucleotide metabolic processGO:0019362280.010
cellular response to growth factor stimulusGO:00713631620.010
anion transmembrane transportGO:0098656770.010
developmental process involved in reproductionGO:00030061590.010
chromatin organizationGO:0006325340.010
regulation of gluconeogenesisGO:000611140.010

Pdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
eye and adnexa diseaseDOID:149200.015
retinal diseaseDOID:567900.015
eye diseaseDOID:561400.015
sensory system diseaseDOID:005015500.015
nervous system diseaseDOID:86300.015
inherited metabolic disorderDOID:65500.015
organic acidemiaDOID:006015900.015
disease of metabolismDOID:001466700.015
amino acid metabolic disorderDOID:925200.015