Rattus norvegicus

41 known processes

Scn2b

sodium channel, voltage-gated, type II, beta

(Aliases: SCNB2)

Scn2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203650.417
cell cell signalingGO:00072673350.388
neurotransmitter transportGO:0006836420.276
organonitrogen compound catabolic processGO:19015651790.252
nitrogen compound transportGO:00717052290.247
regulation of ion transmembrane transporter activityGO:0032412480.232
Human
regulation of sodium ion transmembrane transporter activityGO:200064940.202
Human
positive regulation of transportGO:00510502450.199
secretionGO:00469033070.198
anatomical structure morphogenesisGO:00096532980.183
regulation of phosphatidylinositol dephosphorylationGO:006030410.158
organic anion transportGO:00157111320.152
regulation of molecular functionGO:00650093980.147
Human
cellular component biogenesisGO:00440853680.146
amino acid transportGO:0006865700.145
carboxylic acid transportGO:00469421150.143
regulation of cellular localizationGO:00603412630.142
secretion by cellGO:00329402480.139
neuron developmentGO:00486662860.139
neuron differentiationGO:00301823680.138
monovalent inorganic cation transportGO:00156721720.137
cellular amino acid metabolic processGO:00065201070.135
transmembrane transportGO:00550854120.133
synaptic transmission glycinergicGO:006001220.123
inorganic ion transmembrane transportGO:00986602290.121
organophosphate metabolic processGO:00196373700.116
regulation of phosphate metabolic processGO:00192203490.116
metal ion transportGO:00300012890.115
cation transportGO:00068123820.106
cell projection organizationGO:00300303020.105
neuron projection developmentGO:00311752730.101
phosphatidylinositol dephosphorylationGO:004685640.097
regulation of phosphorus metabolic processGO:00511743490.097
monocarboxylic acid transportGO:0015718520.096
inorganic cation transmembrane transportGO:00986622020.093
circulatory system processGO:00030131830.090
Human
synaptic vesicle endocytosisGO:004848840.090
cell projection morphogenesisGO:00488581230.087
cation transmembrane transportGO:00986552630.086
organic acid metabolic processGO:00060822920.081
organic acid transportGO:00158491160.081
regulation of cellular component organizationGO:00511283680.080
regulation of neurotransmitter levelsGO:0001505420.075
biological adhesionGO:00226101100.074
carbohydrate derivative metabolic processGO:19011353460.073
blood circulationGO:00080151830.073
Human
hormone transportGO:00099141210.071
signal releaseGO:00230611450.070
regulation of multicellular organismal developmentGO:20000263760.069
rhythmic synaptic transmissionGO:006002410.069
ribonucleoside metabolic processGO:00091191740.067
negative regulation of signalingGO:00230571570.065
negative regulation of transportGO:00510511360.064
anion transportGO:00068201780.064
muscle system processGO:00030121150.063
Human
neurotransmitter secretionGO:0007269330.063
gamma aminobutyric acid secretionGO:001405160.061
cellular component morphogenesisGO:00329891550.061
response to histamineGO:003477630.060
potassium ion transportGO:0006813970.060
protein complex subunit organizationGO:00718223020.058
nucleoside monophosphate metabolic processGO:0009123930.057
macromolecular complex assemblyGO:00650032730.057
cellular protein localizationGO:00346131220.056
g protein coupled receptor signaling pathwayGO:00071862420.056
ribonucleotide metabolic processGO:00092592310.055
amine metabolic processGO:0009308380.054
cellular catabolic processGO:00442482950.052
dicarboxylic acid transportGO:0006835340.051
regulation of cation channel activityGO:2001257230.050
cell part morphogenesisGO:00329901230.050
cell morphogenesisGO:00009021420.049
postsynaptic density protein 95 clusteringGO:009711920.049
neurotransmitter gated ion channel clusteringGO:007257830.049
cell adhesionGO:00071551100.047
cellular macromolecule localizationGO:00707271220.047
regulation of cell projection organizationGO:00313441750.046
gamma aminobutyric acid transportGO:001581280.046
muscle contractionGO:0006936880.046
Human
nucleoside metabolic processGO:00091161790.046
regulation of blood vessel sizeGO:0050880890.046
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.045
regulation of cell differentiationGO:00455953200.045
nucleobase containing small molecule metabolic processGO:00550863160.044
regulation of synaptic vesicle exocytosisGO:200030060.044
alpha amino acid metabolic processGO:1901605710.043
cellular metal ion homeostasisGO:00068751720.043
cell morphogenesis involved in neuron differentiationGO:00486671060.042
calcium ion transportGO:00068161310.042
positive regulation of nitrogen compound metabolic processGO:00511733340.042
purine nucleotide metabolic processGO:00061632290.042
regulation of system processGO:00440572080.041
Human
negative regulation of vesicle fusionGO:003133920.041
negative regulation of cell communicationGO:00106481580.041
positive regulation of sodium ion transmembrane transporter activityGO:200065110.041
organic substance catabolic processGO:19015753160.041
aromatic compound catabolic processGO:00194391680.040
dendrite morphogenesisGO:0048813430.040
regulation of hormone levelsGO:00108171870.040
neuron projection morphogenesisGO:00488121220.039
heart processGO:0003015570.039
Human
single organism biosynthetic processGO:00447113420.038
negative regulation of secretionGO:0051048820.038
cellular amine metabolic processGO:0044106380.037
detection of calcium ionGO:000551310.037
membrane depolarization during action potentialGO:008601010.037
Human
cardiac muscle cell action potentialGO:008600150.037
Human
response to inorganic substanceGO:00100353770.037
regulation of cellular amino acid metabolic processGO:000652120.037
regulation of cardiac muscle contractionGO:0055117170.037
Human
synaptic vesicle exocytosisGO:0016079150.036
response to metal ionGO:00100382530.036
regulation of neurotransmitter secretionGO:0046928190.036
positive regulation of phosphorus metabolic processGO:00105622620.035
purine nucleoside metabolic processGO:00422781690.035
cellular component assemblyGO:00226073600.035
cellular chemical homeostasisGO:00550822470.034
positive regulation of secretionGO:00510471400.034
intracellular signal transductionGO:00355563140.034
organic cyclic compound catabolic processGO:19013611750.034
regulation of lipid metabolic processGO:0019216680.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
positive regulation of ion transportGO:0043270940.034
homeostatic processGO:00425923310.034
Human
protein complex biogenesisGO:00702712630.033
regulation of catalytic activityGO:00507903040.033
single organism catabolic processGO:00447122830.033
positive regulation of molecular functionGO:00440932300.033
single organism cellular localizationGO:19025801020.032
brain developmentGO:00074202470.032
regulation of cellular amine metabolic processGO:003323880.032
nucleoside phosphate metabolic processGO:00067532830.032
ribose phosphate metabolic processGO:00196932350.032
cellular component movementGO:00069282480.031
negative regulation of calcium ion dependent exocytosisGO:004595550.031
peptidyl amino acid modificationGO:00181931260.031
protein complex assemblyGO:00064612630.031
nucleotide metabolic processGO:00091172790.031
synaptic transmissionGO:00072682350.030
alpha amino acid catabolic processGO:1901606200.030
organophosphate biosynthetic processGO:00904071430.030
regulation of actin filament based movementGO:1903115120.030
Human
regulation of nervous system developmentGO:00519602640.030
regulation of neurogenesisGO:00507672470.030
regulation of heart contractionGO:0008016480.030
Human
cellular nitrogen compound catabolic processGO:00442701630.030
small molecule catabolic processGO:0044282590.030
positive regulation of neurogenesisGO:00507691650.030
catabolic processGO:00090563510.029
regulation of potassium ion transportGO:0043266290.029
cell substrate adhesionGO:0031589290.029
multicellular organism reproductionGO:00325042330.029
reproductionGO:00000032450.029
neurological system processGO:00508772190.029
macromolecule localizationGO:00330362520.029
cell communication involved in cardiac conductionGO:008606520.028
regulation of cell developmentGO:00602842630.028
negative regulation of cellular biosynthetic processGO:00313271610.028
regulation of synaptic transmissionGO:00508041410.028
endoplasmic reticulum membrane organizationGO:009015810.028
heart morphogenesisGO:000300730.028
amide transportGO:00428861050.028
single organism reproductive processGO:00447022970.028
cellular response to stressGO:00335542690.028
positive regulation of catalytic activityGO:00430851840.028
positive regulation of cellular biosynthetic processGO:00313282950.027
carboxylic acid metabolic processGO:00197522890.027
glycosyl compound metabolic processGO:19016571820.027
single organism behaviorGO:00447081300.027
anion transmembrane transportGO:0098656770.027
regulation of exocytosisGO:0017157370.027
cellular divalent inorganic cation homeostasisGO:00725031620.027
negative regulation of metabolic processGO:00098923310.026
peptide transportGO:0015833970.026
oxoacid metabolic processGO:00434362900.026
intracellular transportGO:00469071850.026
locomotor rhythmGO:004547510.026
ribonucleoside catabolic processGO:00424541260.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
rna metabolic processGO:00160704060.026
positive regulation of phosphate metabolic processGO:00459372620.026
synaptic growth at neuromuscular junctionGO:005112410.026
ribonucleoside triphosphate metabolic processGO:00091991410.025
vesicle organizationGO:0016050290.025
divalent inorganic cation transportGO:00725111340.025
organelle localizationGO:0051640550.025
positive regulation of cell communicationGO:00106472710.025
receptor localization to synapseGO:009712020.024
ion homeostasisGO:00508012120.024
Human
embryonic pattern specificationGO:000988010.024
membrane organizationGO:0061024940.024
regulation of homeostatic processGO:00328441010.024
Human
neuromuscular synaptic transmissionGO:000727420.024
regulation of gamma aminobutyric acid secretionGO:001405260.024
cardiac muscle cell contractionGO:0086003100.024
organonitrogen compound biosynthetic processGO:19015661670.023
cellular amino acid biosynthetic processGO:0008652320.023
choline transportGO:001587140.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
ribonucleoside monophosphate metabolic processGO:0009161880.023
cardiac muscle contractionGO:0060048270.023
Human
purine nucleoside triphosphate catabolic processGO:00091461220.023
cellular homeostasisGO:00197252520.023
purine ribonucleotide metabolic processGO:00091502270.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
negative regulation of secretion by cellGO:1903531720.023
cellular response to histamineGO:007142030.023
cell junction organizationGO:0034330210.023
cell cell junction organizationGO:0045216200.022
single organism membrane organizationGO:0044802740.022
positive regulation of neuron projection developmentGO:0010976990.022
regulation of cellular protein metabolic processGO:00322682670.022
heterocycle catabolic processGO:00467001670.022
carbohydrate derivative catabolic processGO:19011361470.022
cellular amino acid catabolic processGO:0009063210.022
developmental process involved in reproductionGO:00030061590.022
organelle organizationGO:00069962660.022
exocytosisGO:0006887600.022
negative regulation of exocytosisGO:004592070.022
purine ribonucleoside metabolic processGO:00461281680.022
glutamate receptor signaling pathwayGO:0007215430.021
membrane depolarization during cardiac muscle cell action potentialGO:008601210.021
Human
lipid metabolic processGO:00066292830.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
asymmetric protein localizationGO:000810520.021
regulation of neuron projection developmentGO:00109751610.021
cellular potassium ion transportGO:0071804720.021
positive regulation of signalingGO:00230562700.021
small molecule biosynthetic processGO:00442831240.021
actin mediated cell contractionGO:0070252120.021
lipid modificationGO:0030258520.020
response to estradiolGO:00323551640.020
regulation of protein modification processGO:00313991940.020
organic hydroxy compound transportGO:0015850770.020
ribose phosphate biosynthetic processGO:0046390870.020
sodium ion transmembrane transportGO:0035725670.020
circadian rhythmGO:0007623880.020
response to mechanical stimulusGO:00096121340.020
positive regulation of protein modification processGO:00314011420.020
positive regulation of cellular component organizationGO:00511302000.020
regulation of secretionGO:00510462240.019
regulation of transmembrane transporter activityGO:0022898490.019
Human
nucleoside catabolic processGO:00091641260.019
purine containing compound metabolic processGO:00725212530.019
regulation of phosphorylationGO:00423252480.019
cellular ketone metabolic processGO:0042180510.019
positive regulation of synaptic vesicle exocytosisGO:200030230.019
purine ribonucleoside triphosphate catabolic processGO:00092071220.019
purine nucleotide biosynthetic processGO:0006164830.019
protein oligomerizationGO:00512591910.019
central nervous system developmentGO:00074173110.019
regulation of cyclic nucleotide metabolic processGO:0030799510.019
purine containing compound catabolic processGO:00725231380.019
regulation of calcium ion dependent exocytosisGO:0017158110.018
potassium ion transmembrane transportGO:0071805710.018
purine nucleoside triphosphate metabolic processGO:00091441410.018
regulation of ion transportGO:00432692450.018
protein phosphorylationGO:00064683450.018
positive regulation of intracellular protein transportGO:0090316200.018
regulation of neuron differentiationGO:00456642080.018
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.018
single organism organelle organizationGO:19025891800.018
nucleoside triphosphate catabolic processGO:00091431230.018
cell morphogenesis involved in differentiationGO:00009041190.018
cardiovascular system developmentGO:00723581340.018
actin filament based processGO:0030029860.018
peptide secretionGO:0002790860.018
macromolecular complex subunit organizationGO:00439333390.018
heart developmentGO:0007507720.018
regulation of nucleoside metabolic processGO:0009118660.018
positive regulation of developmental processGO:00510942830.018
regulation of rna biosynthetic processGO:20011413810.017
purine ribonucleoside catabolic processGO:00461301240.017
regulation of intracellular signal transductionGO:19025312180.017
purine ribonucleotide biosynthetic processGO:0009152810.017
regulation of cellular ketone metabolic processGO:0010565270.017
establishment of organelle localizationGO:0051656370.017
regulation of peptide hormone secretionGO:0090276800.017
regulation of saliva secretionGO:004687730.017
vesicle mediated transportGO:00161921810.017
nucleobase containing compound catabolic processGO:00346551520.017
dephosphorylationGO:0016311980.017
serotonin receptor signaling pathwayGO:0007210100.017
tube developmentGO:0035295890.017
phospholipid dephosphorylationGO:004683950.017
regulation of blood circulationGO:19035221100.017
Human
endomembrane system organizationGO:0010256480.016
regulation of secretion by cellGO:19035302080.016
intracellular protein transportGO:0006886790.016
synaptic vesicle transportGO:0048489230.016
regulation of peptide transportGO:0090087870.016
behaviorGO:00076102050.016
thigmotaxisGO:000196610.016
cellular response to abiotic stimulusGO:0071214850.016
multicellular organismal signalingGO:0035637440.016
Human
positive regulation of cell developmentGO:00107201760.016
carbohydrate derivative biosynthetic processGO:19011371240.016
regulation of vesicle mediated transportGO:0060627810.016
cellular modified amino acid metabolic processGO:0006575610.016
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.016
action potentialGO:0001508540.016
Human
organ morphogenesisGO:0009887750.016
purine nucleoside catabolic processGO:00061521240.015
regulation of transporter activityGO:0032409500.015
Human
positive regulation of multicellular organismal processGO:00512403870.015
salivary gland developmentGO:000743130.015
response to radiationGO:00093141370.015
regulation of growthGO:00400081050.015
positive regulation of response to stimulusGO:00485842850.015
nucleoside phosphate biosynthetic processGO:19012931020.015
positive regulation of biosynthetic processGO:00098913190.015
regulation of nucleotide metabolic processGO:00061401170.015
transmission of nerve impulseGO:0019226420.015
organic acid catabolic processGO:0016054490.015
organophosphate catabolic processGO:00464341480.015
second messenger mediated signalingGO:0019932510.014
intestinal absorptionGO:005089230.014
cation homeostasisGO:00550801950.014
epithelial cell proliferationGO:0050673540.014
positive regulation of cellular amine metabolic processGO:003324030.014
cellular ion homeostasisGO:00068731840.014
calcium ion transmembrane transportGO:0070588700.014
calcium ion dependent exocytosis of neurotransmitterGO:004879120.014
locomotionGO:00400112370.014
metal ion homeostasisGO:00550651860.014
cellular lipid metabolic processGO:00442552080.014
response to hexoseGO:00097461440.014
localization of cellGO:00516742020.014
positive regulation of nucleotide metabolic processGO:0045981910.014
endoplasmic reticulum organizationGO:000702910.014
nucleoside phosphate catabolic processGO:19012921400.014
positive regulation of gamma aminobutyric acid secretionGO:001405440.014
hemopoiesisGO:0030097340.014
regulation of dendrite developmentGO:0050773590.014
positive regulation of nervous system developmentGO:00519621780.014
alpha amino acid biosynthetic processGO:1901607230.014
positive regulation of amine transportGO:0051954260.014
l glutamate importGO:005193820.014
multicellular organism growthGO:003526410.014
single organism cell adhesionGO:0098602460.013
gonad developmentGO:00084061040.013
insulin secretionGO:0030073690.013
cytosolic calcium ion homeostasisGO:00514801400.013
cellular response to endogenous stimulusGO:00714953770.013
synaptic vesicle localizationGO:0097479240.013
response to ketoneGO:19016541820.013
reproductive structure developmentGO:00486081280.013
establishment of protein localizationGO:00451841410.013
jak stat cascadeGO:0007259260.013
negative regulation of cell deathGO:00605482290.013
regulation of catabolic processGO:00098941130.013
axis specificationGO:000979840.013
multi organism reproductive processGO:00447032620.013
rna biosynthetic processGO:00327743800.013
regulation of cellular component movementGO:00512701500.013
Human
head developmentGO:00603222470.013
regulation of ion transmembrane transportGO:00347651210.013
dna integrity checkpointGO:003157020.013
cell junction assemblyGO:0034329180.013
g protein coupled acetylcholine receptor signaling pathwayGO:000721350.013
single organism intracellular transportGO:19025821660.013
transcription dna templatedGO:00063513770.013
multicellular organismal reproductive processGO:00486092330.013
cellular cation homeostasisGO:00300031800.013
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.013
response to blue lightGO:000963710.013
gamete generationGO:00072761240.013
response to light stimulusGO:0009416520.013
ovulation cycleGO:0042698670.013
regulation of intracellular transportGO:0032386650.012
calcium mediated signalingGO:0019722230.012
reproductive processGO:00224143720.012
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.012
nucleotide biosynthetic processGO:0009165980.012
regulation of nucleotide biosynthetic processGO:0030808470.012
dendrite developmentGO:0016358720.012
ribonucleotide biosynthetic processGO:0009260850.012
cytoskeleton organizationGO:00070101110.012
regulation of membrane potentialGO:00423911100.012
Human
response to peptideGO:19016522920.012
n methyl d aspartate receptor clusteringGO:009711420.012
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathwayGO:000719650.012
positive regulation of neuron differentiationGO:00456661260.012
calcium ion homeostasisGO:00550741620.012
dicarboxylic acid catabolic processGO:004364910.012
protein homooligomerizationGO:0051260910.012
regulation of anatomical structure morphogenesisGO:00226031410.012
regulation of homotypic cell cell adhesionGO:003411040.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
receptor metabolic processGO:0043112180.012
positive regulation of protein phosphorylationGO:00019341350.012
visual perceptionGO:000760130.012
development of primary sexual characteristicsGO:00451371070.012
regulation of embryonic developmentGO:004599520.012
regulation of striated muscle contractionGO:0006942210.012
Human
glycosyl compound catabolic processGO:19016581260.012
response to electrical stimulusGO:0051602560.012
purine nucleotide catabolic processGO:00061951360.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.012
regulation of metal ion transportGO:00109591180.012
Human
vascular process in circulatory systemGO:0003018960.011
positive regulation of ion transmembrane transporter activityGO:0032414130.011
positive regulation of gene expressionGO:00106282440.011
phospholipid metabolic processGO:0006644610.011
regulation of synaptic vesicle transportGO:190280360.011
negative regulation of phosphate metabolic processGO:0045936800.011
regulation of insulin secretionGO:0050796650.011
heart growthGO:0060419200.011
synaptic vesicle recyclingGO:003646550.011
response to ethanolGO:00454711620.011
purine containing compound biosynthetic processGO:0072522850.011
protein heterooligomerizationGO:0051291890.011
response to carbohydrateGO:00097431830.011
negative regulation of phosphorus metabolic processGO:0010563800.011
establishment of synaptic vesicle localizationGO:0097480230.011
programmed cell deathGO:00125013920.011
cyclic purine nucleotide metabolic processGO:0052652620.011
divalent inorganic cation homeostasisGO:00725071650.011
detection of visible lightGO:000958430.011
negative regulation of cellular metabolic processGO:00313242810.011
gliogenesisGO:0042063930.011
regulation of calcineurin nfat signaling cascadeGO:007088430.011
regulation of purine nucleotide metabolic processGO:19005421150.011
nucleotide catabolic processGO:00091661390.011
endocytosisGO:0006897840.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
negative regulation of response to stimulusGO:00485851550.011
response to organophosphorusGO:00466831020.011
negative regulation of macromolecule metabolic processGO:00106052600.011
male sex differentiationGO:0046661640.010
sarcoplasmic reticulum calcium ion transportGO:007029680.010
cell growthGO:00160491040.010
response to peptide hormoneGO:00434342780.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
calcineurin nfat signaling cascadeGO:003317330.010
mononuclear cell migrationGO:007167430.010
gland developmentGO:00487321550.010
agingGO:00075682410.010
protein transportGO:00150311320.010
regulation of synaptic vesicle recyclingGO:190342110.010
negative regulation of uterine smooth muscle contractionGO:007047320.010
response to external biotic stimulusGO:00432072210.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.010
cell motilityGO:00488702020.010
positive regulation of secretion by cellGO:19035321280.010
regulation of cellular component biogenesisGO:0044087860.010
monoamine transportGO:0015844430.010
glutamine family amino acid metabolic processGO:0009064150.010
receptor clusteringGO:0043113130.010
cyclic nucleotide metabolic processGO:0009187800.010

Scn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.031
cancerDOID:16200.031
organ system cancerDOID:005068600.031
gastrointestinal system cancerDOID:311900.031
epilepsy syndromeDOID:182600.029
disease of anatomical entityDOID:700.029
Human
nervous system diseaseDOID:86300.029
brain diseaseDOID:93600.029
central nervous system diseaseDOID:33100.029
intestinal cancerDOID:1015500.010
colon cancerDOID:21900.010
large intestine cancerDOID:567200.010
colorectal cancerDOID:925600.010
hypertensionDOID:1076300.010
vascular diseaseDOID:17800.010
artery diseaseDOID:005082800.010
cardiovascular system diseaseDOID:128700.010
Human