Rattus norvegicus

22 known processes

Il12b

interleukin 12B

(Aliases: Il12)

Il12b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex subunit organizationGO:00439333390.684
response to estrogenGO:00436272320.643
regulation of transcription dna templatedGO:00063553740.602
cell cell signalingGO:00072673350.580
positive regulation of response to stimulusGO:00485842850.495
positive regulation of multicellular organismal processGO:00512403870.451
cellular component biogenesisGO:00440853680.449
response to estradiolGO:00323551640.404
homeostatic processGO:00425923310.403
reproductive processGO:00224143720.396
behaviorGO:00076102050.395
protein complex assemblyGO:00064612630.385
regulation of secretionGO:00510462240.384
cation transportGO:00068123820.384
head developmentGO:00603222470.378
positive regulation of cell communicationGO:00106472710.375
g protein coupled receptor signaling pathwayGO:00071862420.354
response to metal ionGO:00100382530.350
response to woundingGO:00096112540.337
regulation of cell proliferationGO:00421273590.337
regulation of multicellular organismal developmentGO:20000263760.318
regulation of hormone secretionGO:00468831060.306
regulation of response to external stimulusGO:00321011060.302
nucleic acid templated transcriptionGO:00976593790.284
positive regulation of transportGO:00510502450.281
regulation of behaviorGO:0050795610.277
secretionGO:00469033070.273
cellular response to lipidGO:00713962010.267
multi organism reproductive processGO:00447032620.266
central nervous system developmentGO:00074173110.254
multi multicellular organism processGO:00447061380.246
regulation of response to stressGO:00801341260.245
transcription dna templatedGO:00063513770.241
regulation of locomotionGO:00400121480.239
regulation of signal transductionGO:00099663180.236
regulation of nucleic acid templated transcriptionGO:19035063800.235
multicellular organism reproductionGO:00325042330.234
response to lipopolysaccharideGO:00324961910.234
locomotionGO:00400112370.234
chemical homeostasisGO:00488782920.230
positive regulation of developmental processGO:00510942830.230
anatomical structure morphogenesisGO:00096532980.225
response to ethanolGO:00454711620.221
negative regulation of cellular biosynthetic processGO:00313271610.219
negative regulation of multicellular organismal processGO:00512412030.218
cellular component assemblyGO:00226073600.214
apoptotic processGO:00069153810.208
response to inorganic substanceGO:00100353770.199
gland developmentGO:00487321550.198
macromolecule localizationGO:00330362520.195
regulation of apoptotic processGO:00429813350.191
cardiovascular system developmentGO:00723581340.188
transmembrane transportGO:00550854120.186
regulation of programmed cell deathGO:00430673410.185
regulation of cell developmentGO:00602842630.183
hormone transportGO:00099141210.180
regulation of intracellular signal transductionGO:19025312180.178
negative regulation of macromolecule metabolic processGO:00106052600.177
negative regulation of nucleobase containing compound metabolic processGO:00459341530.176
protein complex biogenesisGO:00702712630.172
positive regulation of signalingGO:00230562700.171
anion transportGO:00068201780.170
hormone secretionGO:00468791150.169
brain developmentGO:00074202470.167
negative regulation of metabolic processGO:00098923310.166
blood circulationGO:00080151830.165
secretion by cellGO:00329402480.160
regulation of cellular localizationGO:00603412630.157
multicellular organismal reproductive processGO:00486092330.153
protein complex subunit organizationGO:00718223020.152
response to acid chemicalGO:00011012220.151
single organism reproductive processGO:00447022970.151
regulation of cell differentiationGO:00455953200.150
cellular component movementGO:00069282480.149
macromolecular complex assemblyGO:00650032730.148
transcription from rna polymerase ii promoterGO:00063662520.140
regulation of rna metabolic processGO:00512523910.139
cellular chemical homeostasisGO:00550822470.138
ion transmembrane transportGO:00342203650.133
agingGO:00075682410.129
negative regulation of cell differentiationGO:0045596990.129
positive regulation of macromolecule biosynthetic processGO:00105572470.126
positive regulation of gene expressionGO:00106282440.124
circulatory system processGO:00030131830.124
negative regulation of developmental processGO:00510931250.121
rna metabolic processGO:00160704060.121
regulation of transcription from rna polymerase ii promoterGO:00063572340.121
positive regulation of secretionGO:00510471400.120
reproductive system developmentGO:00614581280.120
organic anion transportGO:00157111320.119
positive regulation of cell migrationGO:0030335960.119
response to transition metal nanoparticleGO:19902671220.119
circulatory system developmentGO:00723591340.116
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.116
wound healingGO:00420601220.116
female gonad developmentGO:0008585530.113
response to carbohydrateGO:00097431830.112
cellular cation homeostasisGO:00300031800.112
negative regulation of programmed cell deathGO:00430691830.111
lipid localizationGO:0010876620.110
response to oxidative stressGO:00069791860.109
reproductionGO:00000032450.108
signal releaseGO:00230611450.107
positive regulation of cellular component movementGO:00512721020.107
leukocyte activationGO:0045321760.105
regulation of cellular component organizationGO:00511283680.104
organ morphogenesisGO:0009887750.104
negative regulation of biosynthetic processGO:00098901680.103
cellular calcium ion homeostasisGO:00068741600.103
negative regulation of cell communicationGO:00106481580.102
regulation of cellular component movementGO:00512701500.101
response to other organismGO:00517072200.100
regulation of nervous system developmentGO:00519602640.098
regulation of system processGO:00440572080.097
cellular response to stressGO:00335542690.096
positive regulation of rna metabolic processGO:00512542030.096
regulation of neurogenesisGO:00507672470.095
negative regulation of transcription dna templatedGO:00458921160.093
positive regulation of cell differentiationGO:00455972170.092
response to hypoxiaGO:00016662310.091
positive regulation of biosynthetic processGO:00098913190.090
positive regulation of nervous system developmentGO:00519621780.089
negative regulation of cellular metabolic processGO:00313242810.087
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010060.086
negative regulation of response to stimulusGO:00485851550.085
positive regulation of nucleobase containing compound metabolic processGO:00459353190.085
carboxylic acid transportGO:00469421150.085
oxoacid metabolic processGO:00434362900.085
positive regulation of cell proliferationGO:00082842490.084
regulation of response to woundingGO:1903034690.084
positive regulation of protein metabolic processGO:00512471780.083
positive regulation of nitrogen compound metabolic processGO:00511733340.083
response to nutrientGO:00075842480.083
negative regulation of transportGO:00510511360.083
negative regulation of gene expressionGO:00106291990.082
regulation of wound healingGO:0061041140.082
negative regulation of nucleic acid templated transcriptionGO:19035071170.082
negative regulation of cell deathGO:00605482290.082
programmed cell deathGO:00125013920.081
positive regulation of neurogenesisGO:00507691650.081
epithelial cell differentiationGO:0030855710.081
negative regulation of nitrogen compound metabolic processGO:00511721610.080
regulation of ion transportGO:00432692450.079
response to bacteriumGO:00096172000.079
single organism behaviorGO:00447081300.078
telencephalon developmentGO:0021537620.077
cellular response to nitrogen compoundGO:19016992100.077
positive regulation of locomotionGO:00400171020.077
organic acid metabolic processGO:00060822920.077
response to growth factorGO:00708481890.076
cellular metal ion homeostasisGO:00068751720.075
cellular homeostasisGO:00197252520.075
regulation of membrane potentialGO:00423911100.074
anterior posterior pattern specificationGO:000995210.074
regulation of neuron differentiationGO:00456642080.073
cellular response to lipopolysaccharideGO:0071222550.073
memoryGO:0007613540.072
response to oxygen levelsGO:00704822650.071
response to external biotic stimulusGO:00432072210.071
negative regulation of response to external stimulusGO:0032102370.071
regulation of rna biosynthetic processGO:20011413810.071
response to toxic substanceGO:00096361330.070
carboxylic acid metabolic processGO:00197522890.070
development of primary female sexual characteristicsGO:0046545560.070
neurological system processGO:00508772190.069
positive regulation of nucleic acid templated transcriptionGO:19035081970.067
neuron differentiationGO:00301823680.066
regulation of hormone levelsGO:00108171870.065
regulation of peptide hormone secretionGO:0090276800.065
anatomical structure formation involved in morphogenesisGO:0048646830.065
catabolic processGO:00090563510.065
negative regulation of macromolecule biosynthetic processGO:00105581480.065
response to molecule of bacterial originGO:00022371940.065
response to ketoneGO:19016541820.064
negative regulation of apoptotic processGO:00430661810.064
tissue developmentGO:00098882520.064
regulation of secretion by cellGO:19035302080.064
negative regulation of wound healingGO:006104580.063
vesicle mediated transportGO:00161921810.063
positive regulation of cellular biosynthetic processGO:00313282950.063
response to biotic stimulusGO:00096072260.063
cognitionGO:0050890920.063
monovalent inorganic cation transportGO:00156721720.062
positive regulation of signal transductionGO:00099671750.062
learning or memoryGO:0007611900.061
cell motilityGO:00488702020.061
divalent metal ion transportGO:00708381320.061
positive regulation of cell motilityGO:2000147970.061
regulation of cellular ketone metabolic processGO:0010565270.061
organelle organizationGO:00069962660.060
lipid metabolic processGO:00066292830.060
divalent inorganic cation homeostasisGO:00725071650.060
localization of cellGO:00516742020.060
response to decreased oxygen levelsGO:00362932370.059
negative regulation of rna biosynthetic processGO:19026791180.059
cytoskeleton organizationGO:00070101110.058
developmental process involved in reproductionGO:00030061590.058
response to ionizing radiationGO:0010212590.058
negative regulation of cell proliferationGO:00082851190.058
organic hydroxy compound metabolic processGO:19016151150.058
positive regulation of intracellular signal transductionGO:19025331380.058
response to peptide hormoneGO:00434342780.055
regulation of anatomical structure morphogenesisGO:00226031410.055
regulation of cell migrationGO:00303341280.055
regulation of immune system processGO:00026821230.055
regulation of body fluid levelsGO:0050878900.054
sexual reproductionGO:00199531480.054
metal ion transportGO:00300012890.054
acute inflammatory responseGO:0002526580.054
regenerationGO:00310991630.052
positive regulation of cellular component organizationGO:00511302000.052
nitrogen compound transportGO:00717052290.052
response to alkaloidGO:00432791320.052
response to glucocorticoidGO:00513842230.051
positive regulation of leukocyte migrationGO:0002687210.051
reproductive structure developmentGO:00486081280.050
mapk cascadeGO:00001651400.050
organonitrogen compound biosynthetic processGO:19015661670.050
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.050
positive regulation of rna biosynthetic processGO:19026801970.050
positive regulation of cytosolic calcium ion concentrationGO:00072041220.050
negative regulation of cell developmentGO:0010721820.049
cytosolic calcium ion homeostasisGO:00514801400.049
cation transmembrane transportGO:00986552630.049
purine ribonucleoside triphosphate metabolic processGO:00092051400.048
cellular amine metabolic processGO:0044106380.048
cellular lipid metabolic processGO:00442552080.048
ion homeostasisGO:00508012120.048
axon developmentGO:0061564960.048
rna biosynthetic processGO:00327743800.048
cell projection organizationGO:00300303020.047
macromolecule catabolic processGO:0009057580.047
neuropeptide signaling pathwayGO:0007218290.047
positive regulation of immune system processGO:0002684900.046
positive regulation of hormone secretionGO:0046887650.045
inflammatory responseGO:00069541500.045
regulation of calcium ion transportGO:0051924770.045
positive regulation of neuron differentiationGO:00456661260.044
cell type specific apoptotic processGO:00972851340.044
organophosphate metabolic processGO:00196373700.044
positive regulation of ion transportGO:0043270940.043
calcium ion homeostasisGO:00550741620.043
intracellular signal transductionGO:00355563140.043
response to reactive oxygen speciesGO:00003021200.043
positive regulation of cell deathGO:00109421840.043
cell migrationGO:00164771970.043
neuron developmentGO:00486662860.043
negative regulation of signalingGO:00230571570.042
peptide hormone secretionGO:0030072840.042
response to peptideGO:19016522920.042
limbic system developmentGO:0021761380.042
pallium developmentGO:0021543420.042
glycerolipid metabolic processGO:0046486670.042
protein heterooligomerizationGO:0051291890.042
monocarboxylic acid transportGO:0015718520.041
positive regulation of cell developmentGO:00107201760.041
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.041
positive regulation of programmed cell deathGO:00430681570.041
response to extracellular stimulusGO:00099913800.041
cellular response to growth factor stimulusGO:00713631620.041
cellular response to hormone stimulusGO:00328702470.040
female pregnancyGO:00075651220.040
synaptic transmissionGO:00072682350.040
sex differentiationGO:00075481130.040
regulation of transmembrane transportGO:00347621220.040
negative regulation of rna metabolic processGO:00512531230.040
response to nutrient levelsGO:00316673700.040
regulation of smooth muscle cell proliferationGO:0048660750.039
positive regulation of cell projection organizationGO:00313461110.039
glycosyl compound metabolic processGO:19016571820.039
peptide metabolic processGO:0006518320.039
s shaped body morphogenesisGO:007205020.038
peptide transportGO:0015833970.038
small gtpase mediated signal transductionGO:0007264360.038
regulation of cell motilityGO:20001451310.038
cellular divalent inorganic cation homeostasisGO:00725031620.038
embryo developmentGO:0009790490.038
cellular modified amino acid metabolic processGO:0006575610.038
positive regulation of secretion by cellGO:19035321280.038
sensory organ developmentGO:0007423740.038
regulation of cellular amine metabolic processGO:003323880.037
regulation of phosphorus metabolic processGO:00511743490.037
neuron projection developmentGO:00311752730.037
cellular amide metabolic processGO:0043603440.037
protein transportGO:00150311320.037
response to glucoseGO:00097491360.036
cellular response to organic cyclic compoundGO:00714072020.036
organic acid transportGO:00158491160.036
positive regulation of catalytic activityGO:00430851840.036
calcium ion transportGO:00068161310.036
eye developmentGO:0001654500.036
regulation of systemic arterial blood pressureGO:0003073300.036
positive regulation of phosphate metabolic processGO:00459372620.035
immune system processGO:00023762040.035
alcohol metabolic processGO:0006066770.035
amide transportGO:00428861050.035
regulation of protein metabolic processGO:00512462890.035
cellular catabolic processGO:00442482950.035
organic substance catabolic processGO:19015753160.035
positive regulation of blood circulationGO:1903524650.035
purine nucleoside triphosphate metabolic processGO:00091441410.034
regulation of acute inflammatory responseGO:0002673230.034
cation homeostasisGO:00550801950.034
neuromuscular processGO:005090520.034
protein oligomerizationGO:00512591910.034
metal ion homeostasisGO:00550651860.033
cell morphogenesis involved in differentiationGO:00009041190.033
cellular response to oxidative stressGO:0034599760.033
synapse assemblyGO:0007416290.033
response to radiationGO:00093141370.033
positive regulation of response to woundingGO:1903036340.032
urinary bladder smooth muscle contractionGO:001483240.032
ribonucleoside metabolic processGO:00091191740.032
response to monosaccharideGO:00342841590.032
positive regulation of phosphorylationGO:00423271770.032
purine containing compound metabolic processGO:00725212530.031
maintenance of locationGO:0051235170.031
regulation of ion transmembrane transportGO:00347651210.031
regulation of molecular functionGO:00650093980.030
regulation of peptide transportGO:0090087870.030
cellular ketone metabolic processGO:0042180510.030
positive regulation of phosphorus metabolic processGO:00105622620.030
regulation of neuron projection developmentGO:00109751610.030
heart developmentGO:0007507720.030
positive regulation of cellular protein metabolic processGO:00322701670.029
protein localizationGO:00081041910.029
negative regulation of chronic inflammatory responseGO:000267720.029
gliogenesisGO:0042063930.029
cellular response to oxygen containing compoundGO:19017013860.029
negative regulation of signal transductionGO:0009968830.029
positive regulation of peptide secretionGO:0002793520.029
purine nucleoside metabolic processGO:00422781690.028
positive regulation of defense responseGO:0031349370.028
cellular response to metal ionGO:0071248550.028
regulation of mapk cascadeGO:00434081160.028
regulation of blood pressureGO:0008217830.028
action potentialGO:0001508540.028
nucleotide metabolic processGO:00091172790.028
actin cytoskeleton organizationGO:0030036730.028
cellular response to endogenous stimulusGO:00714953770.027
cellular ion homeostasisGO:00068731840.027
positive regulation of synaptic transmissionGO:0050806620.027
regulation of protein localizationGO:0032880810.027
protein secretionGO:0009306340.027
positive regulation of nucleoside metabolic processGO:0045979550.027
regulation of reactive oxygen species metabolic processGO:2000377260.026
immune responseGO:00069551040.026
blood vessel developmentGO:0001568690.026
regulation of synaptic plasticityGO:0048167700.026
negative regulation of nervous system developmentGO:0051961790.026
chronic inflammatory responseGO:0002544160.026
positive regulation of cellular amino acid metabolic processGO:004576410.026
muscle cell proliferationGO:0033002840.026
cell activationGO:0001775970.026
forebrain developmentGO:0030900980.025
hepaticobiliary system developmentGO:0061008900.025
cellular response to steroid hormone stimulusGO:0071383930.025
renal system processGO:0003014400.025
actin filament based processGO:0030029860.025
response to calcium ionGO:0051592590.025
response to interleukin 1GO:0070555550.025
cell morphogenesis involved in neuron differentiationGO:00486671060.025
ras protein signal transductionGO:0007265290.024
divalent inorganic cation transportGO:00725111340.024
reactive oxygen species metabolic processGO:0072593370.024
cellular response to acid chemicalGO:0071229750.024
urinary tract smooth muscle contractionGO:001484840.023
response to fatty acidGO:0070542650.023
glial cell differentiationGO:0010001650.023
anion transmembrane transportGO:0098656770.023
regulation of bmp signaling pathwayGO:003051020.023
regulation of cell activationGO:0050865500.023
single organism cellular localizationGO:19025801020.023
positive regulation of transcription dna templatedGO:00458931970.023
growthGO:00400071650.023
liver developmentGO:0001889900.023
regulation of cellular component biogenesisGO:0044087860.023
multicellular organismal homeostasisGO:0048871490.022
cell projection morphogenesisGO:00488581230.022
regulation of growthGO:00400081050.022
amine metabolic processGO:0009308380.022
tube developmentGO:0035295890.022
hippocampus developmentGO:0021766300.022
vasoconstrictionGO:0042310540.022
immune system developmentGO:0002520410.022
positive regulation of protein phosphorylationGO:00019341350.022
nucleoside triphosphate metabolic processGO:00091411440.022
establishment of protein localizationGO:00451841410.021
regulation of cell projection organizationGO:00313441750.021
regulation of cellular protein metabolic processGO:00322682670.021
regulation of neural precursor cell proliferationGO:2000177160.021
regulation of phosphorylationGO:00423252480.021
hematopoietic or lymphoid organ developmentGO:0048534360.021
positive regulation of protein modification processGO:00314011420.021
purine ribonucleotide metabolic processGO:00091502270.021
carbohydrate derivative catabolic processGO:19011361470.021
response to painGO:0048265110.021
single organism catabolic processGO:00447122830.021
lipid biosynthetic processGO:00086101280.021
dna metabolic processGO:0006259960.021
cellular response to hexose stimulusGO:0071331650.021
regulation of peptide secretionGO:0002791820.021
regulation of anatomical structure sizeGO:00900661350.021
organonitrogen compound catabolic processGO:19015651790.020
ossificationGO:0001503700.020
regulation of cellular amino acid metabolic processGO:000652120.020
regulation of cell cycleGO:0051726730.020
fatty acid transportGO:0015908250.020
response to campGO:0051591910.020
development of primary sexual characteristicsGO:00451371070.020
cellular response to reactive oxygen speciesGO:0034614550.020
bmp signaling pathwayGO:003050940.020
positive regulation of mapk cascadeGO:0043410920.020
cellular amino acid metabolic processGO:00065201070.020
oxidation reduction processGO:00551143040.020
response to organophosphorusGO:00466831020.020
sequestering of metal ionGO:005123890.019
ovulation cycleGO:0042698670.019
sensory perception of light stimulusGO:005095330.019
glucose homeostasisGO:0042593750.019
cell fate commitment involved in pattern specificationGO:006058120.019
response to amino acidGO:0043200750.019
negative regulation of uterine smooth muscle contractionGO:007047320.019
regulation of leukocyte activationGO:0002694450.019
vascular process in circulatory systemGO:0003018960.019
ribonucleotide catabolic processGO:00092611360.019
negative regulation of secretionGO:0051048820.019
response to corticosteroidGO:00319602350.019
regulation of muscle tissue developmentGO:1901861250.019
regulation of metal ion transportGO:00109591180.018
regulation of organelle organizationGO:0033043800.018
nucleotide biosynthetic processGO:0009165980.018
regulation of cell adhesionGO:0030155520.018
regulation of synaptic transmissionGO:00508041410.018
cellular response to molecule of bacterial originGO:0071219560.018
acid secretionGO:0046717480.018
positive regulation of peptide hormone secretionGO:0090277500.018
negative regulation of secretion by cellGO:1903531720.018
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.018
nucleoside metabolic processGO:00091161790.018
negative regulation of ion transportGO:0043271510.018
ethanolamine containing compound metabolic processGO:0042439140.018
response to ammonium ionGO:0060359710.018
response to nicotineGO:0035094510.018
response to hexoseGO:00097461440.018
regulation of tube sizeGO:0035150890.018
regulation of cell morphogenesis involved in differentiationGO:0010769720.018
female sex differentiationGO:0046660590.018
mesoderm developmentGO:000749820.018
single organism organelle organizationGO:19025891800.018
defense responseGO:00069521940.018
sensory perception of painGO:0019233730.018
cellular response to corticosteroid stimulusGO:0071384690.017
organophosphate catabolic processGO:00464341480.017
positive regulation of erk1 and erk2 cascadeGO:0070374290.017
cellular nitrogen compound catabolic processGO:00442701630.017
cell cycleGO:00070491010.017
positive regulation of apoptotic processGO:00430651540.017
rhythmic processGO:00485111560.017
axis specificationGO:000979840.017
biological adhesionGO:00226101100.017
response to purine containing compoundGO:00140741260.017
carbohydrate derivative biosynthetic processGO:19011371240.017
regulation of protein modification processGO:00313991940.017
positive regulation of cytokine productionGO:0001819420.017
embryonic pattern specificationGO:000988010.017
camera type eye developmentGO:0043010480.017
ribose phosphate metabolic processGO:00196932350.017
organic hydroxy compound biosynthetic processGO:1901617510.017
regulation of developmental growthGO:0048638450.017
positive regulation of behaviorGO:0048520380.017
gamete generationGO:00072761240.016
regulation of reactive oxygen species biosynthetic processGO:190342650.016
regulation of protein transportGO:0051223680.016
ovulation cycle processGO:0022602500.016
negative regulation of cardiac muscle tissue developmentGO:005502630.016
response to axon injuryGO:0048678590.016
regulation of catabolic processGO:00098941130.016
angiogenesisGO:0001525530.016
heterocycle catabolic processGO:00467001670.016
regulation of cytokine productionGO:0001817560.016
body fluid secretionGO:0007589410.016
smooth muscle cell proliferationGO:0048659770.016
long term synaptic potentiationGO:0060291210.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
tolerance induction dependent upon immune responseGO:000246120.015
carbohydrate derivative metabolic processGO:19011353460.015
renal system developmentGO:0072001670.015
negative regulation of molecular functionGO:00440921330.015
cell adhesionGO:00071551100.015
regulation of cyclic nucleotide metabolic processGO:0030799510.015
muscle cell differentiationGO:0042692520.015

Il12b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.025
steroid inherited metabolic disorderDOID:170100.024
lipid metabolism disorderDOID:314600.024
inherited metabolic disorderDOID:65500.024
congenital adrenal hyperplasiaDOID:005081100.024
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016