Rattus norvegicus

0 known processes

Klk4

kallikrein-related peptidase 4

(Aliases: Emsp1)

Klk4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.044
positive regulation of nitrogen compound metabolic processGO:00511733340.043
rna biosynthetic processGO:00327743800.042
regulation of cell proliferationGO:00421273590.042
neuron differentiationGO:00301823680.040
Rat
intracellular signal transductionGO:00355563140.039
oxoacid metabolic processGO:00434362900.039
response to oxygen levelsGO:00704822650.039
regulation of apoptotic processGO:00429813350.039
programmed cell deathGO:00125013920.038
regulation of phosphorus metabolic processGO:00511743490.038
homeostatic processGO:00425923310.038
cellular response to oxygen containing compoundGO:19017013860.038
transmembrane transportGO:00550854120.038
regulation of cell differentiationGO:00455953200.038
Rat
positive regulation of multicellular organismal processGO:00512403870.037
Rat
regulation of rna biosynthetic processGO:20011413810.037
response to extracellular stimulusGO:00099913800.037
Rat
organic acid metabolic processGO:00060822920.037
positive regulation of cell proliferationGO:00082842490.037
ion transmembrane transportGO:00342203650.037
apoptotic processGO:00069153810.036
rna metabolic processGO:00160704060.036
transcription dna templatedGO:00063513770.036
single organism reproductive processGO:00447022970.036
response to nutrient levelsGO:00316673700.035
Rat
reproductive processGO:00224143720.035
regulation of phosphate metabolic processGO:00192203490.035
nucleic acid templated transcriptionGO:00976593790.034
negative regulation of metabolic processGO:00098923310.034
cellular component biogenesisGO:00440853680.034
regulation of rna metabolic processGO:00512523910.034
response to inorganic substanceGO:00100353770.034
cellular response to endogenous stimulusGO:00714953770.034
regulation of catalytic activityGO:00507903040.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
response to peptideGO:19016522920.033
positive regulation of biosynthetic processGO:00098913190.033
regulation of programmed cell deathGO:00430673410.033
response to acid chemicalGO:00011012220.033
regulation of nucleic acid templated transcriptionGO:19035063800.033
regulation of protein metabolic processGO:00512462890.032
cation transportGO:00068123820.032
cellular ketone metabolic processGO:0042180510.032
carbohydrate derivative metabolic processGO:19011353460.032
regulation of multicellular organismal developmentGO:20000263760.032
Rat
regulation of cellular protein metabolic processGO:00322682670.031
cellular component assemblyGO:00226073600.031
chemical homeostasisGO:00488782920.031
regulation of transcription dna templatedGO:00063553740.031
regulation of cellular ketone metabolic processGO:0010565270.031
single organism biosynthetic processGO:00447113420.031
cellular amine metabolic processGO:0044106380.031
cellular homeostasisGO:00197252520.030
central nervous system developmentGO:00074173110.030
positive regulation of cellular biosynthetic processGO:00313282950.030
cellular response to stressGO:00335542690.030
organophosphate metabolic processGO:00196373700.029
regulation of cellular amino acid metabolic processGO:000652120.029
carboxylic acid metabolic processGO:00197522890.029
amine metabolic processGO:0009308380.029
regulation of cellular amine metabolic processGO:003323880.029
response to decreased oxygen levelsGO:00362932370.029
cell projection organizationGO:00300303020.029
Rat
regulation of cellular component organizationGO:00511283680.029
Rat
response to metal ionGO:00100382530.029
regulation of system processGO:00440572080.028
Rat
cellular amino acid metabolic processGO:00065201070.028
neuron projection developmentGO:00311752730.028
Rat
regulation of signal transductionGO:00099663180.028
cellular response to nitrogen compoundGO:19016992100.028
nucleobase containing small molecule metabolic processGO:00550863160.028
cellular chemical homeostasisGO:00550822470.028
negative regulation of cellular metabolic processGO:00313242810.028
regulation of cell developmentGO:00602842630.027
Rat
multicellular organism reproductionGO:00325042330.027
multi organism reproductive processGO:00447032620.027
secretionGO:00469033070.027
response to ketoneGO:19016541820.027
positive regulation of phosphate metabolic processGO:00459372620.027
protein phosphorylationGO:00064683450.027
catabolic processGO:00090563510.027
rhythmic processGO:00485111560.026
positive regulation of response to stimulusGO:00485842850.026
positive regulation of phosphorus metabolic processGO:00105622620.026
regulation of nervous system developmentGO:00519602640.026
Rat
positive regulation of molecular functionGO:00440932300.026
response to peptide hormoneGO:00434342780.026
response to hypoxiaGO:00016662310.026
agingGO:00075682410.026
positive regulation of developmental processGO:00510942830.026
nucleoside phosphate metabolic processGO:00067532830.026
negative regulation of cell deathGO:00605482290.026
response to woundingGO:00096112540.026
negative regulation of macromolecule metabolic processGO:00106052600.026
protein complex subunit organizationGO:00718223020.025
positive regulation of cell differentiationGO:00455972170.025
anatomical structure morphogenesisGO:00096532980.025
Human
cellular component movementGO:00069282480.025
neuron developmentGO:00486662860.025
Rat
lipid metabolic processGO:00066292830.025
positive regulation of catalytic activityGO:00430851840.025
transcription from rna polymerase ii promoterGO:00063662520.025
tissue developmentGO:00098882520.025
regulation of neurogenesisGO:00507672470.024
Rat
macromolecular complex assemblyGO:00650032730.024
negative regulation of apoptotic processGO:00430661810.024
nucleotide metabolic processGO:00091172790.024
macromolecular complex subunit organizationGO:00439333390.024
multicellular organismal reproductive processGO:00486092330.024
metal ion transportGO:00300012890.024
reproductionGO:00000032450.024
positive regulation of transportGO:00510502450.024
blood circulationGO:00080151830.024
Rat
response to carbohydrateGO:00097431830.024
brain developmentGO:00074202470.024
protein complex assemblyGO:00064612630.024
positive regulation of cell communicationGO:00106472710.024
purine nucleotide metabolic processGO:00061632290.024
positive regulation of gene expressionGO:00106282440.024
cellular response to organonitrogen compoundGO:00714171970.024
regulation of neuron differentiationGO:00456642080.024
Rat
head developmentGO:00603222470.024
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
g protein coupled receptor signaling pathwayGO:00071862420.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
purine ribonucleotide metabolic processGO:00091502270.023
cellular response to organic cyclic compoundGO:00714072020.023
single organism catabolic processGO:00447122830.023
response to estrogenGO:00436272320.023
cellular catabolic processGO:00442482950.023
ribose phosphate metabolic processGO:00196932350.023
regulation of protein modification processGO:00313991940.023
response to corticosteroidGO:00319602350.023
organelle organizationGO:00069962660.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
regulation of phosphorylationGO:00423252480.023
protein complex biogenesisGO:00702712630.023
cellular response to hormone stimulusGO:00328702470.022
positive regulation of cell deathGO:00109421840.022
nitrogen compound transportGO:00717052290.022
purine containing compound metabolic processGO:00725212530.022
response to growth factorGO:00708481890.022
localization of cellGO:00516742020.022
negative regulation of programmed cell deathGO:00430691830.022
ribonucleotide metabolic processGO:00092592310.022
response to oxidative stressGO:00069791860.022
muscle system processGO:00030121150.021
positive regulation of transcription dna templatedGO:00458931970.021
small gtpase mediated signal transductionGO:0007264360.021
positive regulation of rna biosynthetic processGO:19026801970.021
cellular metal ion homeostasisGO:00068751720.021
positive regulation of signalingGO:00230562700.021
positive regulation of rna metabolic processGO:00512542030.021
regulation of locomotionGO:00400121480.021
organic substance catabolic processGO:19015753160.021
regulation of intracellular signal transductionGO:19025312180.021
regulation of cellular localizationGO:00603412630.021
positive regulation of programmed cell deathGO:00430681570.021
ion homeostasisGO:00508012120.021
negative regulation of gene expressionGO:00106291990.021
response to monosaccharideGO:00342841590.020
regulation of protein phosphorylationGO:00019321830.020
cellular response to lipidGO:00713962010.020
locomotionGO:00400112370.020
cation homeostasisGO:00550801950.020
cation transmembrane transportGO:00986552630.020
positive regulation of protein metabolic processGO:00512471780.020
positive regulation of cellular protein metabolic processGO:00322701670.020
positive regulation of cellular component organizationGO:00511302000.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
cell migrationGO:00164771970.020
response to glucocorticoidGO:00513842230.020
neurological system processGO:00508772190.020
regulation of membrane potentialGO:00423911100.020
secretion by cellGO:00329402480.020
response to nutrientGO:00075842480.020
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.019
metal ion homeostasisGO:00550651860.019
response to biotic stimulusGO:00096072260.019
regulation of cell projection organizationGO:00313441750.019
Rat
ras protein signal transductionGO:0007265290.019
cellular ion homeostasisGO:00068731840.019
growthGO:00400071650.019
regulation of secretionGO:00510462240.019
cellular response to growth factor stimulusGO:00713631620.019
anion transportGO:00068201780.019
defense responseGO:00069521940.018
calcium ion homeostasisGO:00550741620.018
regulation of cellular component movementGO:00512701500.018
single organism organelle organizationGO:19025891800.018
negative regulation of multicellular organismal processGO:00512412030.018
synaptic transmissionGO:00072682350.018
regulation of secretion by cellGO:19035302080.018
positive regulation of cellular amine metabolic processGO:003324030.018
divalent inorganic cation homeostasisGO:00725071650.018
cellular cation homeostasisGO:00300031800.018
negative regulation of cell communicationGO:00106481580.018
regulation of cell migrationGO:00303341280.018
regulation of ion transportGO:00432692450.018
macromolecule localizationGO:00330362520.018
positive regulation of protein modification processGO:00314011420.018
response to ethanolGO:00454711620.018
inorganic ion transmembrane transportGO:00986602290.018
cellular calcium ion homeostasisGO:00068741600.018
response to cytokineGO:00340972150.017
cell cell signalingGO:00072673350.017
anterior posterior pattern specificationGO:000995210.017
positive regulation of phosphorylationGO:00423271770.017
positive regulation of apoptotic processGO:00430651540.017
regulation of hydrolase activityGO:00513361430.017
positive regulation of cell developmentGO:00107201760.017
muscle contractionGO:0006936880.017
nucleoside metabolic processGO:00091161790.017
response to alkaloidGO:00432791320.017
Rat
monovalent inorganic cation transportGO:00156721720.017
response to external biotic stimulusGO:00432072210.017
response to bacteriumGO:00096172000.017
multi multicellular organism processGO:00447061380.017
proteolysisGO:00065081750.017
Rat
heart morphogenesisGO:000300730.017
organic cyclic compound catabolic processGO:19013611750.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
response to hexoseGO:00097461440.017
negative regulation of rna biosynthetic processGO:19026791180.017
cell motilityGO:00488702020.017
behaviorGO:00076102050.017
response to glucoseGO:00097491360.017
response to estradiolGO:00323551640.017
positive regulation of signal transductionGO:00099671750.017
response to radiationGO:00093141370.017
negative regulation of biosynthetic processGO:00098901680.017
positive regulation of nervous system developmentGO:00519621780.017
sexual reproductionGO:00199531480.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
regulation of neuron projection developmentGO:00109751610.017
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.016
positive regulation of secretionGO:00510471400.016
protein oligomerizationGO:00512591910.016
glycosyl compound metabolic processGO:19016571820.016
ribonucleoside metabolic processGO:00091191740.016
response to molecule of bacterial originGO:00022371940.016
response to lipopolysaccharideGO:00324961910.016
response to other organismGO:00517072200.016
female pregnancyGO:00075651220.016
cellular response to peptideGO:19016531330.016
organic acid transportGO:00158491160.016
immune system processGO:00023762040.016
regulation of cell motilityGO:20001451310.016
organic anion transportGO:00157111320.016
monocarboxylic acid metabolic processGO:00327871520.016
regenerationGO:00310991630.016
axis specificationGO:000979840.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
positive regulation of neurogenesisGO:00507691650.015
circulatory system processGO:00030131830.015
Rat
regulation of purine nucleotide metabolic processGO:19005421150.015
positive regulation of protein phosphorylationGO:00019341350.015
organonitrogen compound catabolic processGO:19015651790.015
negative regulation of signalingGO:00230571570.015
response to vitaminGO:00332731310.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
organophosphate biosynthetic processGO:00904071430.015
negative regulation of cellular biosynthetic processGO:00313271610.015
regulation of anatomical structure sizeGO:00900661350.015
Rat
response to reactive oxygen speciesGO:00003021200.015
gastrulationGO:000736920.015
purine ribonucleoside metabolic processGO:00461281680.015
developmental process involved in reproductionGO:00030061590.015
regulation of hormone levelsGO:00108171870.015
negative regulation of transportGO:00510511360.015
cytosolic calcium ion homeostasisGO:00514801400.015
response to mechanical stimulusGO:00096121340.015
cardiovascular system developmentGO:00723581340.015
positive regulation of intracellular signal transductionGO:19025331380.015
regulation of response to stressGO:00801341260.014
cellular lipid metabolic processGO:00442552080.014
regulation of anatomical structure morphogenesisGO:00226031410.014
heterocycle catabolic processGO:00467001670.014
positive regulation of cellular component movementGO:00512721020.014
inflammatory responseGO:00069541500.014
nucleobase containing compound catabolic processGO:00346551520.014
cellular nitrogen compound catabolic processGO:00442701630.014
inorganic cation transmembrane transportGO:00986622020.014
divalent metal ion transportGO:00708381320.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
regulation of synaptic transmissionGO:00508041410.014
reproductive structure developmentGO:00486081280.014
response to toxic substanceGO:00096361330.014
regulation of muscle system processGO:0090257790.014
organonitrogen compound biosynthetic processGO:19015661670.014
forebrain developmentGO:0030900980.014
cellular component morphogenesisGO:00329891550.014
regulation of transferase activityGO:00513381230.014
negative regulation of developmental processGO:00510931250.013
calcium ion transportGO:00068161310.013
cellular response to peptide hormone stimulusGO:00713751200.013
lipid biosynthetic processGO:00086101280.013
wound healingGO:00420601220.013
negative regulation of transcription dna templatedGO:00458921160.013
chromosome segregationGO:000705920.013
cell growthGO:00160491040.013
response to purine containing compoundGO:00140741260.013
Rat
reproductive system developmentGO:00614581280.013
regulation of kinase activityGO:00435491170.013
circulatory system developmentGO:00723591340.013
small molecule biosynthetic processGO:00442831240.013
purine ribonucleotide catabolic processGO:00091541360.013
carbohydrate derivative catabolic processGO:19011361470.013
positive regulation of secretion by cellGO:19035321280.013
tube developmentGO:0035295890.013
purine nucleoside metabolic processGO:00422781690.013
regulation of cellular catabolic processGO:00313291010.013
positive regulation of neuron differentiationGO:00456661260.013
regulation of response to external stimulusGO:00321011060.013
carbohydrate derivative biosynthetic processGO:19011371240.013
divalent inorganic cation transportGO:00725111340.013
cellular response to acid chemicalGO:0071229750.013
neuron projection morphogenesisGO:00488121220.013
gland developmentGO:00487321550.013
positive regulation of cell migrationGO:0030335960.013
aromatic compound catabolic processGO:00194391680.013
intracellular transportGO:00469071850.013
positive regulation of nucleotide metabolic processGO:0045981910.013
positive regulation of locomotionGO:00400171020.013
nucleotide catabolic processGO:00091661390.013
peptidyl amino acid modificationGO:00181931260.013
regulation of canonical wnt signaling pathwayGO:006082840.013
regulation of nucleotide metabolic processGO:00061401170.013
cell type specific apoptotic processGO:00972851340.013
purine containing compound catabolic processGO:00725231380.013
positive regulation of cell motilityGO:2000147970.013
cellular response to abiotic stimulusGO:0071214850.013
negative regulation of protein metabolic processGO:00512481140.012
regulation of catabolic processGO:00098941130.012
negative regulation of molecular functionGO:00440921330.012
amide transportGO:00428861050.012
negative regulation of cell differentiationGO:0045596990.012
cytoskeleton organizationGO:00070101110.012
cell part morphogenesisGO:00329901230.012
ribonucleotide catabolic processGO:00092611360.012
cellular response to external stimulusGO:00714961180.012
nucleotide biosynthetic processGO:0009165980.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
cell morphogenesis involved in differentiationGO:00009041190.012
carboxylic acid transportGO:00469421150.012
cell morphogenesisGO:00009021420.012
nucleoside phosphate biosynthetic processGO:19012931020.012
regulation of protein kinase activityGO:00458591050.012
gamete generationGO:00072761240.012
organophosphate catabolic processGO:00464341480.012
response to transition metal nanoparticleGO:19902671220.012
negative regulation of response to stimulusGO:00485851550.012
embryonic pattern specificationGO:000988010.012
action potentialGO:0001508540.012
establishment of tissue polarityGO:000716420.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
oxidation reduction processGO:00551143040.012
positive regulation of cell projection organizationGO:00313461110.012
protein localizationGO:00081041910.012
circadian rhythmGO:0007623880.012
regulation of metal ion transportGO:00109591180.012
single organism intracellular transportGO:19025821660.012
regulation of mapk cascadeGO:00434081160.012
single organism carbohydrate metabolic processGO:00447231180.012
positive regulation of ion transportGO:0043270940.012
positive regulation of hydrolase activityGO:0051345860.012
transmission of nerve impulseGO:0019226420.012
response to insulinGO:00328681330.012
purine nucleotide catabolic processGO:00061951360.012
carbohydrate metabolic processGO:00059751300.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
nucleoside catabolic processGO:00091641260.012
cell projection morphogenesisGO:00488581230.012
hormone secretionGO:00468791150.012
sex differentiationGO:00075481130.012
signal transduction by phosphorylationGO:00230141440.012
nucleoside triphosphate metabolic processGO:00091411440.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
developmental growthGO:00485891000.011
regulation of immune system processGO:00026821230.011
hormone transportGO:00099141210.011
single organism behaviorGO:00447081300.011
cellular response to cytokine stimulusGO:00713451270.011
reactive oxygen species metabolic processGO:0072593370.011
non canonical wnt signaling pathwayGO:003556730.011
negative regulation of rna metabolic processGO:00512531230.011
negative regulation of cell proliferationGO:00082851190.011
cell adhesionGO:00071551100.011
gonad developmentGO:00084061040.011
heart contractionGO:0060047570.011
mapk cascadeGO:00001651400.011
positive regulation of transferase activityGO:0051347810.011
peptide transportGO:0015833970.011
cell activationGO:0001775970.011
regulation of tube sizeGO:0035150890.011
Rat
sensory perceptionGO:00076001010.011
signal releaseGO:00230611450.011
nucleoside phosphate catabolic processGO:19012921400.011
potassium ion transportGO:0006813970.011
negative regulation of cellular protein metabolic processGO:00322691060.011
regulation of blood circulationGO:19035221100.011
Rat
regulation of growthGO:00400081050.011
development of primary sexual characteristicsGO:00451371070.011
cyclic nucleotide metabolic processGO:0009187800.011
muscle cell proliferationGO:0033002840.011
neuronal action potentialGO:0019228350.011
ossificationGO:0001503700.011
negative regulation of cellular component organizationGO:0051129830.011
mesoderm developmentGO:000749820.011
cellular response to alcoholGO:0097306870.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
negative regulation of catalytic activityGO:00430861030.011
purine containing compound biosynthetic processGO:0072522850.011
ribonucleotide biosynthetic processGO:0009260850.011
dephosphorylationGO:0016311980.011
bmp signaling pathwayGO:003050940.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
hepaticobiliary system developmentGO:0061008900.011
purine nucleotide biosynthetic processGO:0006164830.011
morphogenesis of a polarized epitheliumGO:000173810.011
positive regulation of immune system processGO:0002684900.011
regulation of homeostatic processGO:00328441010.011
appendage morphogenesisGO:003510740.011
spermatogenesisGO:0007283990.011
ovulation cycleGO:0042698670.011
gliogenesisGO:0042063930.011
cellular response to steroid hormone stimulusGO:0071383930.011
peptide secretionGO:0002790860.010
organic hydroxy compound metabolic processGO:19016151150.010
nucleoside triphosphate catabolic processGO:00091431230.010
cytoplasmic transportGO:00164821150.010
carbohydrate homeostasisGO:0033500750.010
liver developmentGO:0001889900.010
rho protein signal transductionGO:0007266110.010
lipid storageGO:001991510.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
sequestering of metal ionGO:005123890.010
eye morphogenesisGO:004859240.010
regulation of body fluid levelsGO:0050878900.010
regulation of neuron deathGO:19012141150.010
positive regulation of protein kinase activityGO:0045860730.010
actin filament based processGO:0030029860.010
response to hydrogen peroxideGO:0042542890.010
regulation of smooth muscle cell proliferationGO:0048660750.010
fatty acid metabolic processGO:0006631990.010
positive regulation of kinase activityGO:0033674770.010
chemosensory behaviorGO:000763520.010
heart processGO:0003015570.010
purine nucleoside catabolic processGO:00061521240.010
organ regenerationGO:00311001010.010
reactive nitrogen species metabolic processGO:200105710.010
positive regulation of neuron projection developmentGO:0010976990.010
cell cycleGO:00070491010.010
regulation of peptide transportGO:0090087870.010
salivary gland developmentGO:000743130.010
organ formationGO:004864530.010
reactive oxygen species biosynthetic processGO:190340980.010

Klk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
Human
sensory system diseaseDOID:005015500.022
musculoskeletal system diseaseDOID:1700.019
disease of metabolismDOID:001466700.016
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.015
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.011
retinal diseaseDOID:567900.011
central nervous system diseaseDOID:33100.010