Rattus norvegicus

43 known processes

Klk6

kallikrein related-peptidase 6

(Aliases: Prss9)

Klk6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to purine containing compoundGO:00140741260.267
response to decreased oxygen levelsGO:00362932370.253
response to corticosteroidGO:00319602350.251
cellular response to lipidGO:00713962010.187
response to oxygen levelsGO:00704822650.184
response to hypoxiaGO:00016662310.171
response to metal ionGO:00100382530.146
acute phase responseGO:0006953200.138
immune system processGO:00023762040.134
response to other organismGO:00517072200.126
defense responseGO:00069521940.105
apoptotic processGO:00069153810.097
cellular response to organonitrogen compoundGO:00714171970.094
response to nutrientGO:00075842480.093
Rat
central nervous system developmentGO:00074173110.090
positive regulation of response to stimulusGO:00485842850.086
Human
protein complex subunit organizationGO:00718223020.075
response to transition metal nanoparticleGO:19902671220.074
regulation of cellular component organizationGO:00511283680.074
glial cell developmentGO:0021782190.073
response to nutrient levelsGO:00316673700.073
Rat
macromolecular complex assemblyGO:00650032730.072
response to estrogenGO:00436272320.071
cellular component movementGO:00069282480.070
protein complex biogenesisGO:00702712630.068
regulation of programmed cell deathGO:00430673410.066
cellular lipid metabolic processGO:00442552080.066
action potentialGO:0001508540.064
gliogenesisGO:0042063930.063
regulation of neurotransmitter levelsGO:0001505420.062
negative regulation of nervous system developmentGO:0051961790.059
response to lipopolysaccharideGO:00324961910.058
negative regulation of cell developmentGO:0010721820.056
negative regulation of apoptotic processGO:00430661810.056
renal system developmentGO:0072001670.055
chemical homeostasisGO:00488782920.054
response to cytokineGO:00340972150.054
catabolic processGO:00090563510.053
intermediate filament bundle assemblyGO:004511010.051
regulation of nervous system developmentGO:00519602640.048
regulation of synaptic plasticityGO:0048167700.048
protein homooligomerizationGO:0051260910.048
response to peptideGO:19016522920.048
response to molecule of bacterial originGO:00022371940.046
response to external biotic stimulusGO:00432072210.046
glial cell differentiationGO:0010001650.045
metal ion transportGO:00300012890.044
macromolecular complex subunit organizationGO:00439333390.043
regulation of locomotionGO:00400121480.043
protein complex assemblyGO:00064612630.042
cellular response to oxygen containing compoundGO:19017013860.042
organic anion transportGO:00157111320.041
cellular component assemblyGO:00226073600.041
hormone metabolic processGO:0042445690.041
dicarboxylic acid transportGO:0006835340.040
circulatory system processGO:00030131830.040
Rat
epithelial cell differentiationGO:0030855710.040
biological adhesionGO:00226101100.040
single organism reproductive processGO:00447022970.039
response to inorganic substanceGO:00100353770.038
multicellular organismal signalingGO:0035637440.036
cell cell signalingGO:00072673350.036
programmed cell deathGO:00125013920.036
positive regulation of cell deathGO:00109421840.036
cellular response to organic cyclic compoundGO:00714072020.036
cellular response to nitrogen compoundGO:19016992100.035
response to retinoic acidGO:0032526630.035
multicellular organismal homeostasisGO:0048871490.035
response to hexoseGO:00097461440.034
muscle contractionGO:0006936880.034
response to toxic substanceGO:00096361330.034
response to peptide hormoneGO:00434342780.033
monovalent inorganic cation transportGO:00156721720.033
regulation of cell developmentGO:00602842630.033
cell motilityGO:00488702020.033
response to acid chemicalGO:00011012220.032
blood circulationGO:00080151830.032
Rat
response to extracellular stimulusGO:00099913800.031
Rat
protein oligomerizationGO:00512591910.031
cellular homeostasisGO:00197252520.031
synaptic transmissionGO:00072682350.030
astrocyte developmentGO:001400240.030
cellular response to extracellular stimulusGO:0031668730.030
positive regulation of catalytic activityGO:00430851840.030
regulation of apoptotic processGO:00429813350.030
protein phosphorylationGO:00064683450.029
glucose homeostasisGO:0042593750.029
actin filament based processGO:0030029860.029
response to bacteriumGO:00096172000.029
neurotransmitter transportGO:0006836420.029
cellular component biogenesisGO:00440853680.029
regulation of system processGO:00440572080.029
Rat
regulation of membrane potentialGO:00423911100.029
brain developmentGO:00074202470.029
regulation of cellular protein metabolic processGO:00322682670.028
amine metabolic processGO:0009308380.028
alcohol metabolic processGO:0006066770.028
head developmentGO:00603222470.028
negative regulation of neurogenesisGO:0050768780.028
neuron projection developmentGO:00311752730.028
neurological system processGO:00508772190.028
heart processGO:0003015570.027
cellular response to cytokine stimulusGO:00713451270.027
regulation of cell differentiationGO:00455953200.027
cellular amine metabolic processGO:0044106380.027
response to radiationGO:00093141370.027
positive regulation of cell communicationGO:00106472710.027
Human
positive regulation of apoptotic processGO:00430651540.027
calcium ion homeostasisGO:00550741620.026
muscle system processGO:00030121150.026
cation transportGO:00068123820.026
organonitrogen compound biosynthetic processGO:19015661670.026
response to carbohydrateGO:00097431830.026
response to fatty acidGO:0070542650.026
response to organophosphorusGO:00466831020.025
regulation of blood circulationGO:19035221100.025
Rat
transmission of nerve impulseGO:0019226420.025
sensory perception of painGO:0019233730.025
cellular cation homeostasisGO:00300031800.025
positive regulation of immune system processGO:0002684900.025
carboxylic acid transportGO:00469421150.025
regulation of synaptic transmissionGO:00508041410.025
cellular catabolic processGO:00442482950.024
response to alkaloidGO:00432791320.024
cellular response to peptideGO:19016531330.024
cellular response to hormone stimulusGO:00328702470.024
positive regulation of developmental processGO:00510942830.024
negative regulation of neuron differentiationGO:0045665620.024
cellular amino acid metabolic processGO:00065201070.024
neuron differentiationGO:00301823680.024
positive regulation of nervous system developmentGO:00519621780.024
negative regulation of cell communicationGO:00106481580.024
neuron developmentGO:00486662860.024
amino acid transmembrane transportGO:0003333330.024
inflammatory responseGO:00069541500.023
immune responseGO:00069551040.023
positive regulation of cell developmentGO:00107201760.023
tissue developmentGO:00098882520.023
astrocyte differentiationGO:0048708190.023
regulation of neural precursor cell proliferationGO:2000177160.023
multi organism reproductive processGO:00447032620.022
cellular response to fluid shear stressGO:007149840.022
saliva secretionGO:004654130.022
response to monosaccharideGO:00342841590.022
cell projection organizationGO:00300303020.022
inorganic cation transmembrane transportGO:00986622020.022
rna biosynthetic processGO:00327743800.022
homeostatic processGO:00425923310.022
sensory perceptionGO:00076001010.022
ion transmembrane transportGO:00342203650.022
cellular response to acid chemicalGO:0071229750.022
transcription dna templatedGO:00063513770.022
neuronal action potentialGO:0019228350.022
response to mercury ionGO:0046689150.021
regulation of cell migrationGO:00303341280.021
response to glucocorticoidGO:00513842230.021
response to zinc ionGO:0010043390.021
anion transportGO:00068201780.021
immune effector processGO:0002252530.021
cardiac muscle cell contractionGO:0086003100.021
lipid biosynthetic processGO:00086101280.021
regulation of anatomical structure sizeGO:00900661350.020
Rat
regulation of secretion by cellGO:19035302080.020
negative regulation of programmed cell deathGO:00430691830.020
signal releaseGO:00230611450.020
cellular chemical homeostasisGO:00550822470.020
single organism behaviorGO:00447081300.020
positive regulation of neurogenesisGO:00507691650.020
positive regulation of cellular protein metabolic processGO:00322701670.020
cellular response to endogenous stimulusGO:00714953770.020
cellular hormone metabolic processGO:0034754490.020
regulation of protein modification processGO:00313991940.020
organic substance catabolic processGO:19015753160.020
regulation of blood vessel sizeGO:0050880890.019
Rat
neurotransmitter uptakeGO:000150430.019
protein localizationGO:00081041910.019
response to tumor necrosis factorGO:0034612560.019
cell migrationGO:00164771970.019
cellular ion homeostasisGO:00068731840.019
intermediate filament cytoskeleton organizationGO:004510430.019
regulation of rna biosynthetic processGO:20011413810.019
agingGO:00075682410.019
regulation of immunoglobulin productionGO:000263740.019
cellular response to external stimulusGO:00714961180.019
cellular response to stressGO:00335542690.019
response to vitaminGO:00332731310.018
regenerationGO:00310991630.018
regulation of heart contractionGO:0008016480.018
neural crest cell differentiationGO:001403320.018
cation homeostasisGO:00550801950.018
positive regulation of response to external stimulusGO:0032103510.018
positive regulation of cell differentiationGO:00455972170.018
epithelium developmentGO:0060429960.018
secretionGO:00469033070.018
multicellular organism reproductionGO:00325042330.018
organic acid transportGO:00158491160.018
positive regulation of smooth muscle cell proliferationGO:0048661510.018
negative regulation of synaptic transmission gabaergicGO:003222960.018
acute inflammatory responseGO:0002526580.017
positive regulation of defense responseGO:0031349370.017
positive regulation of signalingGO:00230562700.017
Human
detection of calcium ionGO:000551310.017
regulation of smooth muscle cell migrationGO:0014910360.017
cellular response to tumor necrosis factorGO:0071356460.017
response to ketoneGO:19016541820.016
cytosolic calcium ion homeostasisGO:00514801400.016
negative regulation of cellular metabolic processGO:00313242810.016
single organism biosynthetic processGO:00447113420.016
regulation of neuron projection developmentGO:00109751610.016
cellular response to retinoic acidGO:0071300270.016
divalent inorganic cation homeostasisGO:00725071650.016
regulation of multicellular organismal developmentGO:20000263760.016
cardiac muscle contractionGO:0060048270.016
regulation of hydrolase activityGO:00513361430.016
regulation of cellular amino acid metabolic processGO:000652120.016
positive regulation of molecular functionGO:00440932300.015
secretion by cellGO:00329402480.015
ion homeostasisGO:00508012120.015
cellular response to peptide hormone stimulusGO:00713751200.015
regulation of cellular amine metabolic processGO:003323880.015
regulation of ion transportGO:00432692450.015
regulation of canonical wnt signaling pathwayGO:006082840.015
negative regulation of signalingGO:00230571570.015
detection of stimulusGO:0051606240.015
smooth muscle contractionGO:0006939370.015
peptidyl amino acid modificationGO:00181931260.015
vesicle mediated transportGO:00161921810.015
regulation of behaviorGO:0050795610.015
female pregnancyGO:00075651220.015
heart contractionGO:0060047570.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
negative regulation of metabolic processGO:00098923310.014
response to cgmpGO:007030530.014
regulation of cell proliferationGO:00421273590.014
anatomical structure homeostasisGO:0060249290.014
positive regulation of myeloid leukocyte differentiationGO:000276370.014
gonad developmentGO:00084061040.014
urinary tract smooth muscle contractionGO:001484840.014
regulation of smooth muscle cell proliferationGO:0048660750.014
regulation of anatomical structure morphogenesisGO:00226031410.014
negative regulation of response to stimulusGO:00485851550.014
intracellular transportGO:00469071850.014
cellular lipid catabolic processGO:0044242370.014
regulation of immune system processGO:00026821230.014
amide transportGO:00428861050.014
positive regulation of programmed cell deathGO:00430681570.014
regulation of neurological system processGO:0031644430.014
cellular response to glucocorticoid stimulusGO:0071385680.014
regulation of neurotransmitter uptakeGO:005158010.014
peristalsisGO:003043220.014
ossificationGO:0001503700.014
t cell migrationGO:007267820.014
reproductive structure developmentGO:00486081280.014
regulation of inflammatory responseGO:0050727480.013
regulation of cellular component movementGO:00512701500.013
gamete generationGO:00072761240.013
cellular calcium ion homeostasisGO:00068741600.013
l glutamate importGO:005193820.013
positive regulation of gamma aminobutyric acid secretionGO:001405440.013
positive regulation of catecholamine secretionGO:0033605130.013
b cell activation involved in immune responseGO:000231210.013
kidney developmentGO:0001822670.013
ribose phosphate biosynthetic processGO:0046390870.013
organic acid metabolic processGO:00060822920.013
regulation of response to external stimulusGO:00321011060.013
carbohydrate derivative biosynthetic processGO:19011371240.013
neuron neuron synaptic transmissionGO:0007270600.013
reproductive processGO:00224143720.013
glycerolipid metabolic processGO:0046486670.013
response to activityGO:0014823730.013
morphogenesis of embryonic epitheliumGO:001633130.013
localization of cellGO:00516742020.013
intermediate filament based processGO:004510330.013
potassium ion transmembrane transportGO:0071805710.013
carboxylic acid metabolic processGO:00197522890.013
regulation of hormone secretionGO:00468831060.013
response to insulinGO:00328681330.013
cellular ketone metabolic processGO:0042180510.013
sensory organ developmentGO:0007423740.012
multicellular organism growthGO:003526410.012
immunoglobulin mediated immune responseGO:001606440.012
cytoskeleton organizationGO:00070101110.012
response to campGO:0051591910.012
carbohydrate derivative metabolic processGO:19011353460.012
regulation of neurogenesisGO:00507672470.012
negative regulation of cell deathGO:00605482290.012
negative regulation of glutamate secretionGO:001405090.012
organ regenerationGO:00311001010.012
cellular response to hexose stimulusGO:0071331650.012
positive regulation of phosphorus metabolic processGO:00105622620.012
sexual reproductionGO:00199531480.012
chemotaxisGO:0006935660.012
negative regulation of multicellular organismal processGO:00512412030.012
regulation of ossificationGO:0030278320.012
positive regulation of cytokine productionGO:0001819420.012
regulation of response to woundingGO:1903034690.012
phospholipid metabolic processGO:0006644610.012
multicellular organismal reproductive processGO:00486092330.012
locomotionGO:00400112370.012
regulation of rna metabolic processGO:00512523910.012
negative regulation of cell differentiationGO:0045596990.012
response to estradiolGO:00323551640.012
positive regulation of cell motilityGO:2000147970.012
actin filament based movementGO:0030048160.012
response to glucoseGO:00097491360.011
regulation of sensory perception of painGO:0051930290.011
sequestering of metal ionGO:005123890.011
positive regulation of inflammatory responseGO:0050729240.011
neural precursor cell proliferationGO:0061351230.011
circadian rhythmGO:0007623880.011
rhythmic behaviorGO:0007622240.011
copulationGO:0007620170.011
g protein coupled receptor signaling pathwayGO:00071862420.011
Human
innate immune responseGO:0045087350.011
cellular response to growth factor stimulusGO:00713631620.011
regulation of muscle contractionGO:0006937530.011
regulation of signal transductionGO:00099663180.011
Human
cell adhesionGO:00071551100.011
oxoacid metabolic processGO:00434362900.011
excretionGO:0007588240.011
cerebellar granule cell precursor proliferationGO:002193010.011
b cell mediated immunityGO:001972440.011
prostate gland epithelium morphogenesisGO:006074020.011
protein kinase c activating g protein coupled receptor signaling pathwayGO:0007205120.011
ensheathment of neuronsGO:0007272400.011
cellular protein complex assemblyGO:0043623440.011
positive regulation of cell projection organizationGO:00313461110.011
cellular response to carbohydrate stimulusGO:0071322720.011
detection of temperature stimulus involved in sensory perception of painGO:005096540.011
multi multicellular organism processGO:00447061380.011
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of cellular biosynthetic processGO:00313282950.011
regulation of molecular functionGO:00650093980.011
intermediate filament organizationGO:004510910.011
cellular amino acid biosynthetic processGO:0008652320.011
regulation of catalytic activityGO:00507903040.011
regulation of muscle system processGO:0090257790.011
positive regulation of multicellular organismal processGO:00512403870.011
Rat
myeloid leukocyte migrationGO:0097529200.011
myelinationGO:0042552390.011
cellular response to monosaccharide stimulusGO:0071326670.011
response to oxidative stressGO:00069791860.011
regulation of hormone levelsGO:00108171870.011
regulation of map kinase activityGO:0043405530.010
defense response to gram negative bacteriumGO:005082930.010
single organism catabolic processGO:00447122830.010
glycerophospholipid metabolic processGO:0006650470.010
membrane organizationGO:0061024940.010
anatomical structure morphogenesisGO:00096532980.010
cellular response to glucose stimulusGO:0071333650.010
positive regulation of organic acid transportGO:0032892220.010
circulatory system developmentGO:00723591340.010
spermatogenesisGO:0007283990.010
response to phGO:0009268270.010
endomembrane system organizationGO:0010256480.010
male gamete generationGO:0048232990.010
hormone transportGO:00099141210.010
regulation of saliva secretionGO:004687730.010
proteolysisGO:00065081750.010
metal ion homeostasisGO:00550651860.010
neural crest cell developmentGO:001403220.010

Klk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.044
eye diseaseDOID:561400.044
disease of anatomical entityDOID:700.044
eye and adnexa diseaseDOID:149200.044
nervous system diseaseDOID:86300.044
retinal diseaseDOID:567900.033
gastrointestinal system diseaseDOID:7700.030
musculoskeletal system diseaseDOID:1700.021
retinal degenerationDOID:846600.019
connective tissue diseaseDOID:6500.012
vascular diseaseDOID:17800.011
cardiovascular system diseaseDOID:128700.011
central nervous system diseaseDOID:33100.010