Rattus norvegicus

51 known processes

Cdc42bpa

CDC42 binding protein kinase alpha

(Aliases: Pk428,Mrck)

Cdc42bpa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.241
regulation of transcription dna templatedGO:00063553740.155
protein phosphorylationGO:00064683450.138
transcription dna templatedGO:00063513770.131
rna metabolic processGO:00160704060.130
cell migrationGO:00164771970.120
positive regulation of cellular component organizationGO:00511302000.107
programmed cell deathGO:00125013920.098
nucleic acid templated transcriptionGO:00976593790.098
regulation of protein phosphorylationGO:00019321830.090
regulation of phosphate metabolic processGO:00192203490.084
regulation of multicellular organismal developmentGO:20000263760.084
anatomical structure morphogenesisGO:00096532980.083
transcription from rna polymerase ii promoterGO:00063662520.083
regulation of phosphorus metabolic processGO:00511743490.080
regulation of transcription from rna polymerase ii promoterGO:00063572340.079
positive regulation of nitrogen compound metabolic processGO:00511733340.076
cellular component movementGO:00069282480.076
regulation of signal transductionGO:00099663180.075
rna biosynthetic processGO:00327743800.075
cellular component biogenesisGO:00440853680.074
Fly
apoptotic processGO:00069153810.074
neuron developmentGO:00486662860.073
Fly
regulation of cellular component organizationGO:00511283680.070
Fly
regulation of apoptotic processGO:00429813350.070
cell projection organizationGO:00300303020.070
negative regulation of gene expressionGO:00106291990.067
regulation of catalytic activityGO:00507903040.067
negative regulation of metabolic processGO:00098923310.067
regulation of rna biosynthetic processGO:20011413810.067
regulation of cellular protein metabolic processGO:00322682670.062
regulation of molecular functionGO:00650093980.059
single organism reproductive processGO:00447022970.058
regulation of nucleic acid templated transcriptionGO:19035063800.058
regulation of protein metabolic processGO:00512462890.056
regulation of cell morphogenesis involved in differentiationGO:0010769720.056
organelle organizationGO:00069962660.055
vesicle mediated transportGO:00161921810.054
regulation of synaptic growth at neuromuscular junctionGO:000858210.051
regulation of neuron differentiationGO:00456642080.050
organic substance catabolic processGO:19015753160.049
localization of cellGO:00516742020.049
cell motilityGO:00488702020.049
neuron differentiationGO:00301823680.049
Fly
tissue developmentGO:00098882520.049
response to nutrient levelsGO:00316673700.048
reproductionGO:00000032450.048
multicellular organism reproductionGO:00325042330.047
multi organism reproductive processGO:00447032620.047
brain developmentGO:00074202470.047
regulation of dendrite developmentGO:0050773590.046
mesoderm developmentGO:000749820.046
single organism catabolic processGO:00447122830.046
catabolic processGO:00090563510.045
head developmentGO:00603222470.044
multicellular organismal reproductive processGO:00486092330.044
positive regulation of nucleobase containing compound metabolic processGO:00459353190.043
regulation of rna metabolic processGO:00512523910.042
negative regulation of cell proliferationGO:00082851190.042
central nervous system developmentGO:00074173110.042
cell morphogenesis involved in neuron differentiationGO:00486671060.041
regulation of anatomical structure morphogenesisGO:00226031410.041
regulation of cell developmentGO:00602842630.040
synaptic transmissionGO:00072682350.039
neuron projection developmentGO:00311752730.039
positive regulation of gene expressionGO:00106282440.039
small gtpase mediated signal transductionGO:0007264360.039
cell morphogenesisGO:00009021420.039
positive regulation of signalingGO:00230562700.039
cellular component assemblyGO:00226073600.038
Fly
reproductive processGO:00224143720.038
cellular catabolic processGO:00442482950.037
negative regulation of signalingGO:00230571570.037
positive regulation of biosynthetic processGO:00098913190.037
secretionGO:00469033070.037
regulation of phosphorylationGO:00423252480.037
regulation of protein modification processGO:00313991940.037
macromolecular complex assemblyGO:00650032730.036
Fly
response to hypoxiaGO:00016662310.036
gastrulationGO:000736920.036
regulation of programmed cell deathGO:00430673410.035
positive regulation of transportGO:00510502450.035
negative regulation of cellular metabolic processGO:00313242810.035
cellular component morphogenesisGO:00329891550.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
positive regulation of cellular biosynthetic processGO:00313282950.035
nucleoside triphosphate catabolic processGO:00091431230.035
positive regulation of cell communicationGO:00106472710.034
cell type specific apoptotic processGO:00972851340.034
negative regulation of multicellular organismal processGO:00512412030.034
response to decreased oxygen levelsGO:00362932370.033
cellular response to stressGO:00335542690.033
neuron apoptotic processGO:0051402880.032
response to extracellular stimulusGO:00099913800.032
ras protein signal transductionGO:0007265290.032
Rat
locomotionGO:00400112370.032
regulation of neuron projection developmentGO:00109751610.032
regulation of cell differentiationGO:00455953200.032
regulation of cellular amino acid metabolic processGO:000652120.032
axonogenesisGO:0007409710.031
cell projection morphogenesisGO:00488581230.031
positive regulation of rna biosynthetic processGO:19026801970.031
aromatic compound catabolic processGO:00194391680.031
negative regulation of response to stimulusGO:00485851550.031
regulation of cellular amine metabolic processGO:003323880.031
organophosphate metabolic processGO:00196373700.031
regulation of nervous system developmentGO:00519602640.030
regulation of cellular ketone metabolic processGO:0010565270.030
response to oxygen levelsGO:00704822650.030
negative regulation of programmed cell deathGO:00430691830.030
negative regulation of cell communicationGO:00106481580.030
positive regulation of response to stimulusGO:00485842850.029
cellular amino acid metabolic processGO:00065201070.029
positive regulation of signal transductionGO:00099671750.029
nucleotide catabolic processGO:00091661390.029
sexual reproductionGO:00199531480.029
circulatory system developmentGO:00723591340.029
cell part morphogenesisGO:00329901230.028
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
signal releaseGO:00230611450.028
nucleobase containing small molecule metabolic processGO:00550863160.028
anterior posterior pattern specificationGO:000995210.028
negative regulation of molecular functionGO:00440921330.028
regulation of neurogenesisGO:00507672470.027
nucleobase containing compound catabolic processGO:00346551520.027
carbohydrate derivative catabolic processGO:19011361470.027
cation homeostasisGO:00550801950.027
cellular nitrogen compound catabolic processGO:00442701630.027
macromolecular complex subunit organizationGO:00439333390.027
Fly
positive regulation of transcription dna templatedGO:00458931970.027
regulation of intracellular signal transductionGO:19025312180.027
cellular amine metabolic processGO:0044106380.027
positive regulation of neurogenesisGO:00507691650.026
vesicle localizationGO:0051648330.026
purine nucleotide catabolic processGO:00061951360.026
embryonic skeletal system morphogenesisGO:004870430.026
vasculature developmentGO:0001944700.025
cellular ketone metabolic processGO:0042180510.025
nucleoside phosphate catabolic processGO:19012921400.025
ribonucleotide catabolic processGO:00092611360.025
organophosphate catabolic processGO:00464341480.025
negative regulation of developmental processGO:00510931250.025
embryonic skeletal system developmentGO:004870630.025
organelle localizationGO:0051640550.025
Mouse
regulation of cell projection organizationGO:00313441750.025
actin filament based processGO:0030029860.025
male mating behaviorGO:006017930.024
negative regulation of cellular biosynthetic processGO:00313271610.024
regulation of kinase activityGO:00435491170.024
secretion by cellGO:00329402480.024
negative regulation of apoptotic processGO:00430661810.024
positive regulation of nervous system developmentGO:00519621780.024
ribose phosphate metabolic processGO:00196932350.024
positive regulation of cellular amine metabolic processGO:003324030.024
synaptic growth at neuromuscular junctionGO:005112410.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
regulation of small gtpase mediated signal transductionGO:0051056480.023
organic cyclic compound catabolic processGO:19013611750.023
heterocycle catabolic processGO:00467001670.023
positive regulation of programmed cell deathGO:00430681570.023
amine metabolic processGO:0009308380.023
establishment of vesicle localizationGO:0051650310.023
regulation of protein kinase activityGO:00458591050.023
negative regulation of cell deathGO:00605482290.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.022
formation of primary germ layerGO:000170410.022
response to growth factorGO:00708481890.022
vasculogenesisGO:000157030.022
reproductive system developmentGO:00614581280.022
regulation of neuron apoptotic processGO:0043523830.022
nucleotide metabolic processGO:00091172790.022
epithelium developmentGO:0060429960.022
positive regulation of cellular protein metabolic processGO:00322701670.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
growthGO:00400071650.021
negative regulation of macromolecule metabolic processGO:00106052600.021
response to nutrientGO:00075842480.021
axon developmentGO:0061564960.021
positive regulation of molecular functionGO:00440932300.021
negative regulation of catalytic activityGO:00430861030.021
positive regulation of developmental processGO:00510942830.021
carbohydrate derivative metabolic processGO:19011353460.021
macromolecule localizationGO:00330362520.021
axis specificationGO:000979840.021
negative regulation of macromolecule biosynthetic processGO:00105581480.020
positive regulation of neuron projection developmentGO:0010976990.020
regulation of cellular catabolic processGO:00313291010.020
gland developmentGO:00487321550.020
dendrite morphogenesisGO:0048813430.020
positive regulation of apoptotic processGO:00430651540.020
regulation of cell proliferationGO:00421273590.020
protein autophosphorylationGO:0046777660.020
cytoskeleton organizationGO:00070101110.020
positive regulation of cell developmentGO:00107201760.020
positive regulation of rna metabolic processGO:00512542030.020
negative regulation of rna biosynthetic processGO:19026791180.020
nucleoside metabolic processGO:00091161790.020
cellular response to oxygen containing compoundGO:19017013860.020
positive regulation of cell differentiationGO:00455972170.019
regulation of cell morphogenesisGO:0022604770.019
cellular response to growth factor stimulusGO:00713631620.019
synaptic vesicle endocytosisGO:004848840.019
negative regulation of protein metabolic processGO:00512481140.019
nucleoside triphosphate metabolic processGO:00091411440.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
purine nucleoside metabolic processGO:00422781690.019
glycosyl compound catabolic processGO:19016581260.019
response to metal ionGO:00100382530.019
bmp signaling pathwayGO:003050940.019
response to woundingGO:00096112540.019
purine containing compound metabolic processGO:00725212530.019
neural crest cell developmentGO:001403220.019
single organism cellular localizationGO:19025801020.018
cytoskeleton dependent cytokinesisGO:006164020.018
negative regulation of rna metabolic processGO:00512531230.018
single organism membrane organizationGO:0044802740.018
regulation of secretion by cellGO:19035302080.018
negative regulation of biosynthetic processGO:00098901680.018
negative regulation of cellular protein metabolic processGO:00322691060.018
positive regulation of phosphate metabolic processGO:00459372620.017
inorganic cation transmembrane transportGO:00986622020.017
organic acid metabolic processGO:00060822920.017
positive regulation of neuron differentiationGO:00456661260.017
proteolysisGO:00065081750.017
developmental growthGO:00485891000.017
adult locomotory behaviorGO:000834440.017
peptidyl amino acid modificationGO:00181931260.017
neuron deathGO:00709971270.017
blood vessel morphogenesisGO:0048514580.017
purine containing compound catabolic processGO:00725231380.017
positive regulation of cell proliferationGO:00082842490.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
regulation of transferase activityGO:00513381230.017
embryo developmentGO:0009790490.017
response to hydrogen peroxideGO:0042542890.017
synaptic vesicle transportGO:0048489230.017
regulation of neuron deathGO:19012141150.017
single organism organelle organizationGO:19025891800.016
response to estrogenGO:00436272320.016
positive regulation of protein phosphorylationGO:00019341350.016
nitrogen compound transportGO:00717052290.016
tube formationGO:003514830.016
synaptic vesicle localizationGO:0097479240.016
cell cell signalingGO:00072673350.016
protein complex subunit organizationGO:00718223020.016
Fly
neuron projection morphogenesisGO:00488121220.016
cardiovascular system developmentGO:00723581340.016
rhythmic processGO:00485111560.016
regulation of secretionGO:00510462240.016
divalent inorganic cation homeostasisGO:00725071650.016
homeostatic processGO:00425923310.016
regulation of hydrolase activityGO:00513361430.016
response to acid chemicalGO:00011012220.016
dendrite developmentGO:0016358720.016
positive regulation of cell projection organizationGO:00313461110.016
purine ribonucleotide catabolic processGO:00091541360.016
regulation of dendrite morphogenesisGO:0048814330.016
positive regulation of cell deathGO:00109421840.016
positive regulation of phosphorus metabolic processGO:00105622620.016
microtubule organizing center organizationGO:003102310.015
negative regulation of signal transductionGO:0009968830.015
epithelial cell differentiationGO:0030855710.015
neural crest cell differentiationGO:001403320.015
protein oligomerizationGO:00512591910.015
regulation of synaptic transmissionGO:00508041410.015
gamete generationGO:00072761240.015
negative regulation of transcription dna templatedGO:00458921160.015
developmental process involved in reproductionGO:00030061590.015
spermatogenesisGO:0007283990.015
development of primary sexual characteristicsGO:00451371070.015
response to biotic stimulusGO:00096072260.015
protein complex assemblyGO:00064612630.015
Fly
regulation of cellular localizationGO:00603412630.015
transmission of nerve impulseGO:0019226420.015
neuronal action potentialGO:0019228350.015
regulation of peptide hormone secretionGO:0090276800.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
morphogenesis of embryonic epitheliumGO:001633130.015
cellular homeostasisGO:00197252520.015
peptidyl serine phosphorylationGO:0018105330.015
mesoderm morphogenesisGO:004833210.015
nucleoside catabolic processGO:00091641260.015
cell adhesionGO:00071551100.015
cellular chemical homeostasisGO:00550822470.014
response to peptideGO:19016522920.014
purine ribonucleotide metabolic processGO:00091502270.014
ion transmembrane transportGO:00342203650.014
cell morphogenesis involved in differentiationGO:00009041190.014
cellular response to reactive oxygen speciesGO:0034614550.014
multicellular organismal signalingGO:0035637440.014
cellular cation homeostasisGO:00300031800.014
rho protein signal transductionGO:0007266110.014
Rat
cell growthGO:00160491040.014
regulation of response to stressGO:00801341260.014
regulation of mapk cascadeGO:00434081160.014
camera type eye developmentGO:0043010480.014
regulation of cellular component biogenesisGO:0044087860.014
Fly
membrane organizationGO:0061024940.014
positive regulation of multicellular organismal processGO:00512403870.014
mitotic spindle organizationGO:000705220.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
regulation of vesicle mediated transportGO:0060627810.014
gonad developmentGO:00084061040.013
developmental growth involved in morphogenesisGO:0060560330.013
response to glucoseGO:00097491360.013
eye morphogenesisGO:004859240.013
eye developmentGO:0001654500.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
establishment of tissue polarityGO:000716420.013
positive regulation of protein metabolic processGO:00512471780.013
organ morphogenesisGO:0009887750.013
cation transportGO:00068123820.013
response to monosaccharideGO:00342841590.013
protein complex biogenesisGO:00702712630.013
Fly
insulin secretionGO:0030073690.013
axon cargo transportGO:000808810.013
response to external biotic stimulusGO:00432072210.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
hormone secretionGO:00468791150.013
reproductive structure developmentGO:00486081280.013
regulation of bmp signaling pathwayGO:003051020.013
regulation of hormone levelsGO:00108171870.013
cellular macromolecular complex assemblyGO:0034622580.013
Fly
establishment of organelle localizationGO:0051656370.013
Mouse
axis elongationGO:000340120.013
glycosyl compound metabolic processGO:19016571820.013
positive regulation of focal adhesion assemblyGO:005189420.013
spindle organizationGO:000705120.013
actin cytoskeleton organizationGO:0030036730.013
purine nucleoside catabolic processGO:00061521240.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.013
regulation of axonogenesisGO:0050770370.013
positive regulation of intracellular signal transductionGO:19025331380.013
cellular response to organic cyclic compoundGO:00714072020.013
response to oxidative stressGO:00069791860.012
purine ribonucleoside catabolic processGO:00461301240.012
response to hexoseGO:00097461440.012
response to peptide hormoneGO:00434342780.012
metal ion homeostasisGO:00550651860.012
cellular response to nitrogen compoundGO:19016992100.012
positive regulation of phosphorylationGO:00423271770.012
cellular metal ion homeostasisGO:00068751720.012
male gamete generationGO:0048232990.012
tube developmentGO:0035295890.012
purine ribonucleoside metabolic processGO:00461281680.012
blood vessel developmentGO:0001568690.012
single organism biosynthetic processGO:00447113420.012
response to inorganic substanceGO:00100353770.012
cellular response to endogenous stimulusGO:00714953770.012
response to carbohydrateGO:00097431830.012
cell cycleGO:00070491010.012
regulation of canonical wnt signaling pathwayGO:006082840.012
hormone transportGO:00099141210.012
heart morphogenesisGO:000300730.012
wound healingGO:00420601220.012
ribonucleoside metabolic processGO:00091191740.012
carboxylic acid metabolic processGO:00197522890.012
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.012
action potentialGO:0001508540.012
ribonucleoside catabolic processGO:00424541260.012
lipid modificationGO:0030258520.012
forebrain developmentGO:0030900980.012
positive regulation of catalytic activityGO:00430851840.012
regulation of epithelial cell differentiationGO:0030856120.012
germ cell migrationGO:000835410.012
chemical homeostasisGO:00488782920.012
circadian rhythmGO:0007623880.012
peptide hormone secretionGO:0030072840.012
embryonic pattern specificationGO:000988010.012
cellular macromolecule localizationGO:00707271220.011
regulation of cell motilityGO:20001451310.011
actin filament based movementGO:0030048160.011
regulation of cell cycleGO:0051726730.011
regulation of cell migrationGO:00303341280.011
purine nucleotide metabolic processGO:00061632290.011
neuromuscular synaptic transmissionGO:000727420.011
negative regulation of neuron apoptotic processGO:0043524450.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
glandular epithelial cell differentiationGO:000206740.011
positive regulation of transferase activityGO:0051347810.011
muscle structure developmentGO:0061061870.011
intracellular transportGO:00469071850.011
mapk cascadeGO:00001651400.011
regulation of growthGO:00400081050.011
cell cycle checkpointGO:000007520.011
cellular response to oxygen levelsGO:0071453600.011
neurotransmitter secretionGO:0007269330.011
response to alkaloidGO:00432791320.011
dna integrity checkpointGO:003157020.011
mesoderm formationGO:000170710.011
positive regulation of protein modification processGO:00314011420.011
behaviorGO:00076102050.011
regulation of insulin secretionGO:0050796650.011
centrosome organizationGO:005129710.011
cytokinetic processGO:003250610.011
oxoacid metabolic processGO:00434362900.011
regulation of synaptic plasticityGO:0048167700.011
regulation of catabolic processGO:00098941130.011
nucleoside phosphate metabolic processGO:00067532830.011
cardiac conductionGO:006133720.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
peptidyl serine modificationGO:0018209340.010
immune responseGO:00069551040.010
transforming growth factor beta receptor complex assemblyGO:000718120.010
sex differentiationGO:00075481130.010
positive regulation of mapk cascadeGO:0043410920.010
agingGO:00075682410.010
response to vitaminGO:00332731310.010
inorganic ion transmembrane transportGO:00986602290.010
endocytosisGO:0006897840.010
circulatory system processGO:00030131830.010
neuromuscular processGO:005090520.010
negative regulation of heart growthGO:006111730.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
response to other organismGO:00517072200.010
circadian regulation of gene expressionGO:003292230.010
reactive oxygen species biosynthetic processGO:190340980.010
organonitrogen compound catabolic processGO:19015651790.010

Cdc42bpa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.047
cancerDOID:16200.034
organ system cancerDOID:005068600.034
disease of cellular proliferationDOID:1456600.034
disease of metabolismDOID:001466700.014
gastrointestinal system cancerDOID:311900.013
central nervous system diseaseDOID:33100.012
inherited metabolic disorderDOID:65500.012
neuromuscular diseaseDOID:44000.011
neuropathyDOID:87000.011