Rattus norvegicus

100 known processes

Bak1

BCL2-antagonist/killer 1

(Aliases: MGC108627)

Bak1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of fc receptor mediated stimulatory signaling pathwayGO:006036830.321
myeloid leukocyte activationGO:0002274360.200
positive regulation of rna metabolic processGO:00512542030.157
regulation of secretionGO:00510462240.154
nucleic acid templated transcriptionGO:00976593790.138
anatomical structure morphogenesisGO:00096532980.130
cellular response to oxygen containing compoundGO:19017013860.126
response to cytokineGO:00340972150.120
Rat
response to other organismGO:00517072200.119
response to oxidative stressGO:00069791860.119
cell junction organizationGO:0034330210.116
response to corticosteroidGO:00319602350.113
Rat
intracellular transportGO:00469071850.108
Human
positive regulation of cell communicationGO:00106472710.103
regulation of immune responseGO:0050776550.102
response to heatGO:0009408600.099
Rat
regulation of phosphate metabolic processGO:00192203490.096
positive regulation of nucleobase containing compound metabolic processGO:00459353190.093
leukocyte activationGO:0045321760.091
response to hydrogen peroxideGO:0042542890.090
immune system processGO:00023762040.088
neuron projection developmentGO:00311752730.087
transcription from rna polymerase ii promoterGO:00063662520.086
fc receptor mediated stimulatory signaling pathwayGO:000243130.085
regulation of apoptotic processGO:00429813350.080
regulation of cellular localizationGO:00603412630.080
positive regulation of platelet derived growth factor receptor signaling pathwayGO:001064110.077
brain developmentGO:00074202470.076
response to peptide hormoneGO:00434342780.076
Rat
signal transduction by phosphorylationGO:00230141440.076
response to carbohydrateGO:00097431830.075
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.074
biological adhesionGO:00226101100.072
macromolecular complex subunit organizationGO:00439333390.070
regulation of signal transductionGO:00099663180.070
programmed cell deathGO:00125013920.070
positive regulation of mitochondrion organizationGO:001082240.069
cell cell signalingGO:00072673350.069
regulation of neurogenesisGO:00507672470.069
immune responseGO:00069551040.068
positive regulation of nitrogen compound metabolic processGO:00511733340.066
positive regulation of cellular component organizationGO:00511302000.065
positive regulation of signalingGO:00230562700.065
response to monosaccharideGO:00342841590.065
Rat
positive regulation of release of cytochrome c from mitochondriaGO:009020030.064
negative regulation of nitrogen compound metabolic processGO:00511721610.063
response to external biotic stimulusGO:00432072210.060
negative regulation of programmed cell deathGO:00430691830.059
Rat
regulation of secretion by cellGO:19035302080.059
response to biotic stimulusGO:00096072260.059
positive regulation of multicellular organismal processGO:00512403870.058
positive regulation of isotype switchingGO:004583010.058
negative regulation of apoptotic processGO:00430661810.057
Rat
regulation of rna metabolic processGO:00512523910.057
synaptic growth at neuromuscular junctionGO:005112410.057
negative regulation of signalingGO:00230571570.056
regulation of programmed cell deathGO:00430673410.054
regulation of cellular amine metabolic processGO:003323880.053
transcription dna templatedGO:00063513770.053
neuron apoptotic processGO:0051402880.053
negative regulation of response to stimulusGO:00485851550.053
developmental process involved in reproductionGO:00030061590.052
Rat
cell cell junction organizationGO:0045216200.052
regulation of cellular component organizationGO:00511283680.050
regulation of phosphorylationGO:00423252480.050
cellular amino acid metabolic processGO:00065201070.048
organic substance catabolic processGO:19015753160.048
b cell activation involved in immune responseGO:000231210.048
cell cycle checkpointGO:000007520.048
apoptotic processGO:00069153810.048
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.047
single organism carbohydrate metabolic processGO:00447231180.047
positive regulation of rna biosynthetic processGO:19026801970.047
positive regulation of response to stimulusGO:00485842850.047
negative regulation of cellular metabolic processGO:00313242810.047
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.046
regulation of cellular amino acid metabolic processGO:000652120.046
transmembrane transportGO:00550854120.046
Human
positive regulation of biosynthetic processGO:00098913190.045
regulation of phosphorus metabolic processGO:00511743490.044
secretionGO:00469033070.044
negative regulation of cell communicationGO:00106481580.044
monovalent inorganic cation transportGO:00156721720.043
negative regulation of cell deathGO:00605482290.043
Rat
positive regulation of transferase activityGO:0051347810.043
regulation of transcription dna templatedGO:00063553740.043
regulation of vesicle mediated transportGO:0060627810.042
central nervous system developmentGO:00074173110.042
positive regulation of immune system processGO:0002684900.042
cellular ion homeostasisGO:00068731840.042
positive regulation of phosphate metabolic processGO:00459372620.041
single organism cellular localizationGO:19025801020.041
ion homeostasisGO:00508012120.041
cellular response to organonitrogen compoundGO:00714171970.041
defense responseGO:00069521940.040
regulation of cell developmentGO:00602842630.040
cytosolic calcium ion homeostasisGO:00514801400.040
chemical homeostasisGO:00488782920.040
head developmentGO:00603222470.039
negative regulation of developmental processGO:00510931250.039
regulation of cell cycleGO:0051726730.039
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.039
positive regulation of cell deathGO:00109421840.039
protein phosphorylationGO:00064683450.038
response to toxic substanceGO:00096361330.038
regulation of rna biosynthetic processGO:20011413810.038
cellular component movementGO:00069282480.038
positive regulation of cellular amine metabolic processGO:003324030.037
positive regulation of protein phosphorylationGO:00019341350.037
regulation of cell differentiationGO:00455953200.037
tissue remodelingGO:0048771400.037
regulation of mapk cascadeGO:00434081160.037
negative regulation of rna metabolic processGO:00512531230.037
cell adhesionGO:00071551100.037
regulation of intracellular signal transductionGO:19025312180.037
regulation of membrane potentialGO:00423911100.037
Human
response to nutrient levelsGO:00316673700.036
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.036
cell projection morphogenesisGO:00488581230.036
single organism intracellular transportGO:19025821660.036
Human
membrane organizationGO:0061024940.036
Human Rat
single organism membrane organizationGO:0044802740.036
Human Rat
regulation of protein transportGO:0051223680.035
neuron differentiationGO:00301823680.034
cytokine productionGO:0001816610.033
positive regulation of immune responseGO:0050778420.033
regulation of nervous system developmentGO:00519602640.033
intracellular signal transductionGO:00355563140.033
olfactory learningGO:000835510.033
cell cycle processGO:0022402570.033
positive regulation of programmed cell deathGO:00430681570.033
positive regulation of secretion by cellGO:19035321280.033
chemosensory behaviorGO:000763520.032
positive regulation of secretionGO:00510471400.032
positive regulation of signal transductionGO:00099671750.032
regulation of protein metabolic processGO:00512462890.032
Human Rat
regulation of neuron differentiationGO:00456642080.032
protein complex assemblyGO:00064612630.032
response to reactive oxygen speciesGO:00003021200.032
response to hypoxiaGO:00016662310.032
Rat
cellular response to endogenous stimulusGO:00714953770.032
positive regulation of mapk cascadeGO:0043410920.031
neuronal action potentialGO:0019228350.031
protein complex subunit organizationGO:00718223020.031
cytoplasmic transportGO:00164821150.031
mast cell activationGO:0045576150.030
positive regulation of phosphorus metabolic processGO:00105622620.030
cellular cation homeostasisGO:00300031800.030
response to nutrientGO:00075842480.030
Rat
vesicle mediated transportGO:00161921810.030
sequestering of metal ionGO:005123890.030
catabolic processGO:00090563510.030
positive regulation of nervous system developmentGO:00519621780.030
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.030
cell part morphogenesisGO:00329901230.029
lymphocyte homeostasisGO:000226020.029
positive regulation of kinase activityGO:0033674770.029
response to oxygen levelsGO:00704822650.029
Rat
gland developmentGO:00487321550.029
cellular chemical homeostasisGO:00550822470.029
positive regulation of transcription dna templatedGO:00458931970.029
regulation of protein kinase activityGO:00458591050.029
rna metabolic processGO:00160704060.029
cellular calcium ion homeostasisGO:00068741600.029
sequestering of calcium ionGO:005120880.028
positive regulation of fc receptor mediated stimulatory signaling pathwayGO:006036910.028
response to inorganic substanceGO:00100353770.028
organ regenerationGO:00311001010.028
chromatin assembly or disassemblyGO:000633310.028
regulation of transferase activityGO:00513381230.028
cellular divalent inorganic cation homeostasisGO:00725031620.028
secretion by cellGO:00329402480.028
regulation of protein phosphorylationGO:00019321830.027
divalent inorganic cation homeostasisGO:00725071650.027
receptor metabolic processGO:0043112180.027
cellular component assemblyGO:00226073600.027
carbohydrate metabolic processGO:00059751300.027
positive regulation of cytosolic calcium ion concentrationGO:00072041220.027
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.026
myeloid leukocyte differentiationGO:0002573200.026
regulation of molecular functionGO:00650093980.026
Human Rat
regulation of immune system processGO:00026821230.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
cell activationGO:0001775970.026
regulation of mitochondrion organizationGO:001082170.026
positive regulation of cellular amino acid metabolic processGO:004576410.026
protein complex biogenesisGO:00702712630.026
negative regulation of transcription dna templatedGO:00458921160.026
signal releaseGO:00230611450.026
olfactory behaviorGO:004204820.025
reproductionGO:00000032450.025
Rat
immunoglobulin mediated immune responseGO:001606440.025
macromolecule localizationGO:00330362520.025
cellular metal ion homeostasisGO:00068751720.025
positive regulation of immunoglobulin productionGO:000263940.025
amine metabolic processGO:0009308380.025
positive regulation of gene expressionGO:00106282440.025
endomembrane system organizationGO:0010256480.024
response to axon injuryGO:0048678590.024
regulation of kinase activityGO:00435491170.024
positive regulation of cell differentiationGO:00455972170.024
regulation of organelle organizationGO:0033043800.023
response to extracellular stimulusGO:00099913800.023
Rat
cytoskeleton organizationGO:00070101110.023
neuron developmentGO:00486662860.023
response to decreased oxygen levelsGO:00362932370.023
Rat
cellular response to insulin stimulusGO:0032869810.023
regulation of protein localizationGO:0032880810.023
response to peptideGO:19016522920.023
Rat
t cell homeostasisGO:004302920.023
cellular response to peptide hormone stimulusGO:00713751200.023
macromolecular complex assemblyGO:00650032730.023
response to amino acidGO:0043200750.022
Rat
cellular catabolic processGO:00442482950.022
regulation of ion transportGO:00432692450.022
metal ion homeostasisGO:00550651860.022
tube developmentGO:0035295890.022
synapse organizationGO:0050808460.022
cation transportGO:00068123820.022
rhythmic processGO:00485111560.022
Rat
response to woundingGO:00096112540.022
regulation of cytokine productionGO:0001817560.021
multicellular organismal reproductive processGO:00486092330.021
Rat
anion transmembrane transportGO:0098656770.021
leukocyte activation involved in immune responseGO:0002366160.021
negative regulation of nucleic acid templated transcriptionGO:19035071170.021
protein transportGO:00150311320.021
regulation of leukocyte activationGO:0002694450.021
response to lipopolysaccharideGO:00324961910.021
positive regulation of gtpase activityGO:0043547470.021
reactive nitrogen species metabolic processGO:200105710.021
negative regulation of macromolecule metabolic processGO:00106052600.021
developmental growthGO:00485891000.021
response to mechanical stimulusGO:00096121340.021
Human
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
negative regulation of signal transductionGO:0009968830.021
positive regulation of protein kinase activityGO:0045860730.021
cellular component biogenesisGO:00440853680.021
positive regulation of protein modification processGO:00314011420.020
cell morphogenesisGO:00009021420.020
response to glucocorticoidGO:00513842230.020
Rat
mammary gland developmentGO:0030879380.020
positive regulation of cellular biosynthetic processGO:00313282950.020
purine ribonucleoside triphosphate metabolic processGO:00092051400.020
positive regulation of molecular functionGO:00440932300.020
Human
peptidyl serine modificationGO:0018209340.020
regulation of cellular component movementGO:00512701500.020
regulation of system processGO:00440572080.020
negative regulation of cellular biosynthetic processGO:00313271610.020
hormone secretionGO:00468791150.020
cellular carbohydrate metabolic processGO:0044262720.020
regulation of catalytic activityGO:00507903040.020
Human Rat
response to ketoneGO:19016541820.020
Rat
homeostatic processGO:00425923310.020
positive regulation of protein serine threonine kinase activityGO:0071902520.020
calcium ion homeostasisGO:00550741620.020
response to metal ionGO:00100382530.019
Rat
negative regulation of homeostatic processGO:0032845470.019
embryonic neurocranium morphogenesisGO:004870220.019
cell projection organizationGO:00300303020.019
response to molecule of fungal originGO:000223830.019
cellular response to cytokine stimulusGO:00713451270.019
positive regulation of cell proliferationGO:00082842490.019
localization of cellGO:00516742020.019
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.019
cellular response to stressGO:00335542690.019
Human
oxoacid metabolic processGO:00434362900.019
negative regulation of gene expressionGO:00106291990.019
response to hexoseGO:00097461440.019
regulation of cytoskeleton organizationGO:0051493490.019
positive regulation of intracellular signal transductionGO:19025331380.019
endocytosisGO:0006897840.018
nitrogen compound transportGO:00717052290.018
response to molecule of bacterial originGO:00022371940.018
regulation of isotype switchingGO:004519110.018
neuron projection morphogenesisGO:00488121220.018
negative regulation of mitotic cell cycle phase transitionGO:190199130.018
regulation of cell proliferationGO:00421273590.018
regulation of locomotionGO:00400121480.018
regulation of cell morphogenesisGO:0022604770.018
positive regulation of protein metabolic processGO:00512471780.018
Human
immune effector processGO:0002252530.018
dna metabolic processGO:0006259960.018
regulation of response to stressGO:00801341260.018
Human
small gtpase mediated signal transductionGO:0007264360.017
negative regulation of metabolic processGO:00098923310.017
cellular response to hormone stimulusGO:00328702470.017
organonitrogen compound biosynthetic processGO:19015661670.017
cellular amine metabolic processGO:0044106380.017
cellular response to growth factor stimulusGO:00713631620.017
tissue developmentGO:00098882520.017
organophosphate metabolic processGO:00196373700.017
metal ion transportGO:00300012890.017
single organism reproductive processGO:00447022970.017
Rat
positive regulation of lipid kinase activityGO:009021820.017
response to alkaloidGO:00432791320.017
Rat
axis specificationGO:000979840.017
mammary gland morphogenesisGO:006044360.016
regulation of synaptic transmissionGO:00508041410.016
regulation of neuron projection developmentGO:00109751610.016
agingGO:00075682410.016
positive regulation of neurogenesisGO:00507691650.016
cell cell junction assemblyGO:000704370.016
regulation of skeletal muscle tissue growthGO:004863130.016
mapk cascadeGO:00001651400.016
regulation of hormone levelsGO:00108171870.016
negative regulation of rna biosynthetic processGO:19026791180.016
regulation of cell motilityGO:20001451310.016
negative regulation of cell cycle phase transitionGO:190198840.016
salivary gland developmentGO:000743130.016
regulation of endocytosisGO:0030100420.016
carbohydrate derivative metabolic processGO:19011353460.016
transmission of nerve impulseGO:0019226420.016
heart morphogenesisGO:000300730.016
cell type specific apoptotic processGO:00972851340.016
Rat
somatic recombination of immunoglobulin gene segmentsGO:001644710.016
mitotic cell cycle checkpointGO:000709310.016
positive regulation of apoptotic processGO:00430651540.016
cellular response to peptideGO:19016531330.015
negative regulation of biosynthetic processGO:00098901680.015
female pregnancyGO:00075651220.015
cell migrationGO:00164771970.015
regulation of establishment of protein localizationGO:0070201690.015
regulation of defense responseGO:0031347680.015
single organism catabolic processGO:00447122830.015
cation homeostasisGO:00550801950.015
regulation of intracellular transportGO:0032386650.015
positive regulation of cell developmentGO:00107201760.015
regenerationGO:00310991630.015
cell morphogenesis involved in differentiationGO:00009041190.015
response to purine containing compoundGO:00140741260.015
Rat
regulation of mast cell activationGO:003300390.015
aromatic compound catabolic processGO:00194391680.015
craniofacial suture morphogenesisGO:009709440.015
regulation of map kinase activityGO:0043405530.015
exocytosisGO:0006887600.015
regulation of neuron apoptotic processGO:0043523830.015
positive regulation of map kinase activityGO:0043406460.015
regulation of protein modification processGO:00313991940.015
response to growth factorGO:00708481890.015
response to ethanolGO:00454711620.014
negative regulation of transportGO:00510511360.014
positive regulation of cytokine productionGO:0001819420.014
regulation of cellular protein metabolic processGO:00322682670.014
Human Rat
cellular response to extracellular stimulusGO:0031668730.014
regulation of protein complex assemblyGO:0043254330.014
nucleotide metabolic processGO:00091172790.014
alpha beta t cell differentiationGO:004663220.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
positive regulation of transportGO:00510502450.014
regulation of metal ion transportGO:00109591180.014
cell activation involved in immune responseGO:0002263160.014
nucleobase containing small molecule metabolic processGO:00550863160.014
actin filament based processGO:0030029860.014
immune response regulating signaling pathwayGO:0002764190.014
embryonic skeletal system morphogenesisGO:004870430.014
cellular homeostasisGO:00197252520.014
glial cell apoptotic processGO:003434980.013
Rat
inflammatory responseGO:00069541500.013
activation of immune responseGO:0002253260.013
positive regulation of phosphorylationGO:00423271770.013
proteolysisGO:00065081750.013
Human Rat
regulation of dendrite morphogenesisGO:0048814330.013
carboxylic acid metabolic processGO:00197522890.013
regulation of cellular component biogenesisGO:0044087860.013
regulation of protein oligomerizationGO:003245920.013
rna biosynthetic processGO:00327743800.013
alternative mrna splicing via spliceosomeGO:000038040.013
single organismal cell cell adhesionGO:0016337420.013
regulation of erk1 and erk2 cascadeGO:0070372410.013
embryonic skeletal system developmentGO:004870630.013
histamine secretion involved in inflammatory responseGO:000244130.013
leukocyte mediated immunityGO:0002443280.013
single organism behaviorGO:00447081300.013
organonitrogen compound catabolic processGO:19015651790.013
ras protein signal transductionGO:0007265290.012
dna packagingGO:000632340.012
organic anion transportGO:00157111320.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
establishment of protein localizationGO:00451841410.012
positive regulation of cellular protein metabolic processGO:00322701670.012
Human
platelet aggregationGO:007052740.012
regulation of protein secretionGO:0050708280.012
smad protein complex assemblyGO:000718310.012
regulation of anatomical structure morphogenesisGO:00226031410.012
receptor mediated endocytosisGO:0006898420.012
release of sequestered calcium ion into cytosolGO:0051209250.012
embryonic pattern specificationGO:000988010.012
response to corticosteroneGO:0051412400.012
Rat
reproductive system developmentGO:00614581280.012
Rat
cellular protein localizationGO:00346131220.012
sex differentiationGO:00075481130.012
Rat
negative regulation of cell matrix adhesionGO:000195330.012
organelle organizationGO:00069962660.012
negative regulation of catalytic activityGO:00430861030.012
Rat
lipid metabolic processGO:00066292830.012
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.012
protein localizationGO:00081041910.012
negative regulation of skeletal muscle tissue developmentGO:004864230.012
formation of primary germ layerGO:000170410.012
protein autophosphorylationGO:0046777660.012
organelle localizationGO:0051640550.012
purine containing compound catabolic processGO:00725231380.012
divalent inorganic cation transportGO:00725111340.012
golgi vesicle transportGO:0048193220.012
protein secretionGO:0009306340.012
digestive tract developmentGO:0048565390.012
response to radiationGO:00093141370.012
positive regulation of cellular component movementGO:00512721020.012
ensheathment of neuronsGO:0007272400.011
nucleoside phosphate metabolic processGO:00067532830.011
regulation of growthGO:00400081050.011
reactive oxygen species metabolic processGO:0072593370.011
cellular macromolecular complex assemblyGO:0034622580.011
response to glucoseGO:00097491360.011
regulation of dendrite developmentGO:0050773590.011
inorganic ion transmembrane transportGO:00986602290.011
ribonucleotide catabolic processGO:00092611360.011
regulation of cell projection organizationGO:00313441750.011
g protein coupled receptor signaling pathwayGO:00071862420.011
nucleoside metabolic processGO:00091161790.011
negative regulation of phosphorylationGO:0042326570.011
histamine secretion by mast cellGO:000255330.011
cellular response to nitrogen compoundGO:19016992100.011
thyroid gland developmentGO:003087810.011
anion transportGO:00068201780.011
regulation of carbohydrate metabolic processGO:0006109410.011
chromosome organizationGO:0051276360.011
response to bacteriumGO:00096172000.011
epidermal growth factor receptor signaling pathwayGO:0007173230.011
amide transportGO:00428861050.011
maintenance of locationGO:0051235170.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
response to acid chemicalGO:00011012220.011
Rat
organophosphate catabolic processGO:00464341480.011
cell motilityGO:00488702020.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123950.011
purine ribonucleoside catabolic processGO:00461301240.011
regulation of proteasomal protein catabolic processGO:006113640.010
regulation of cellular ketone metabolic processGO:0010565270.010
cell matrix adhesionGO:0007160190.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.010
response to progesteroneGO:0032570480.010
dna integrity checkpointGO:003157020.010
erbb signaling pathwayGO:0038127230.010
lymphocyte activation involved in immune responseGO:000228530.010
response to ammonium ionGO:0060359710.010
Rat
synaptic transmissionGO:00072682350.010
regulation of neuron deathGO:19012141150.010
regulation of protein serine threonine kinase activityGO:0071900640.010
response to electrical stimulusGO:0051602560.010
Rat
cell substrate adhesionGO:0031589290.010
organic cyclic compound catabolic processGO:19013611750.010
dna recombinationGO:000631030.010

Bak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
intestinal cancerDOID:1015500.030
gastrointestinal system cancerDOID:311900.030
colon cancerDOID:21900.030
organ system cancerDOID:005068600.030
disease of cellular proliferationDOID:1456600.030
colorectal cancerDOID:925600.030
large intestine cancerDOID:567200.030
cancerDOID:16200.030
nervous system diseaseDOID:86300.019
disease of anatomical entityDOID:700.019
sensory system diseaseDOID:005015500.013
colon carcinomaDOID:152000.011