Rattus norvegicus

0 known processes

RT1-DMb

RT1 class II, locus DMb

(Aliases: RT1.Mb,RT1.DMb)

RT1-DMb biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neutrophil migrationGO:190262260.948
antigen processing and presentation of peptide antigen via mhc class iiGO:000249510.927
Mouse
antigen processing and presentation of peptide antigenGO:004800220.811
Mouse
negative regulation of t cell activationGO:005086870.809
regulation of t cell activationGO:0050863230.709
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000250410.706
Mouse
regulation of t cell proliferationGO:0042129170.616
negative regulation of lymphocyte activationGO:0051250100.591
leukocyte apoptotic processGO:007188760.569
negative regulation of mononuclear cell proliferationGO:003294560.560
negative regulation of lymphocyte proliferationGO:005067260.548
innate immune responseGO:0045087350.530
regulation of mononuclear cell proliferationGO:0032944260.502
positive regulation of neutrophil chemotaxisGO:009002350.485
positive regulation of lymphocyte differentiationGO:004562160.433
mononuclear cell proliferationGO:0032943290.382
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.353
Mouse
t cell proliferationGO:0042098190.341
antigen processing and presentationGO:001988220.329
Mouse
defense responseGO:00069521940.326
cellular component biogenesisGO:00440853680.320
negative regulation of leukocyte proliferationGO:007066460.309
cellular component assemblyGO:00226073600.305
de novo protein foldingGO:000645820.291
Mouse
immune system processGO:00023762040.287
Mouse
negative regulation of cell activationGO:0050866150.287
cellular response to ammonium ionGO:0071242170.277
positive regulation of lymphocyte proliferationGO:0050671200.263
protein complex subunit organizationGO:00718223020.263
macromolecular complex assemblyGO:00650032730.258
negative regulation of leukocyte apoptotic processGO:200010740.250
t cell activationGO:0042110290.243
icosanoid metabolic processGO:0006690380.240
regulation of cell activationGO:0050865500.238
negative regulation of t cell proliferationGO:004213050.238
macromolecular complex subunit organizationGO:00439333390.228
negative regulation of immune system processGO:0002683390.224
cellular macromolecular complex assemblyGO:0034622580.217
immunoglobulin mediated immune responseGO:001606440.216
b cell mediated immunityGO:001972440.210
protein complex biogenesisGO:00702712630.181
negative regulation of leukocyte activationGO:0002695140.170
cellular response to endogenous stimulusGO:00714953770.169
cellular lipid metabolic processGO:00442552080.159
chaperone mediated protein folding requiring cofactorGO:005108520.158
Mouse
protein complex assemblyGO:00064612630.153
positive regulation of t cell differentiationGO:004558260.150
regulation of protein phosphorylationGO:00019321830.143
negative regulation of apoptotic processGO:00430661810.142
leukocyte activationGO:0045321760.139
lymphocyte homeostasisGO:000226020.137
single organism organelle organizationGO:19025891800.135
cellular response to nitrogen compoundGO:19016992100.135
response to fungusGO:000962080.133
programmed cell deathGO:00125013920.127
intracellular signal transductionGO:00355563140.125
regulation of leukocyte proliferationGO:0070663260.124
regulation of phosphorylationGO:00423252480.120
chemotaxisGO:0006935660.120
regulation of leukocyte activationGO:0002694450.118
regulation of lymphocyte proliferationGO:0050670260.116
regulation of cell proliferationGO:00421273590.112
carboxylic acid biosynthetic processGO:0046394830.109
actin filament based processGO:0030029860.106
cation transportGO:00068123820.103
organic acid biosynthetic processGO:0016053830.102
cellular response to organonitrogen compoundGO:00714171970.100
vesicle mediated transportGO:00161921810.100
granulocyte chemotaxisGO:0071621150.096
regulation of homotypic cell cell adhesionGO:003411040.094
leukocyte proliferationGO:0070661290.092
cellular response to peptide hormone stimulusGO:00713751200.091
regulation of leukocyte apoptotic processGO:200010650.090
lymphocyte proliferationGO:0046651290.089
regulation of immune system processGO:00026821230.088
cellular response to stressGO:00335542690.088
cellular protein complex assemblyGO:0043623440.088
cell activationGO:0001775970.086
carboxylic acid metabolic processGO:00197522890.079
lipid metabolic processGO:00066292830.078
antigen processing and presentation of exogenous antigenGO:001988410.075
Mouse
cellular response to organic cyclic compoundGO:00714072020.074
regulation of phosphorus metabolic processGO:00511743490.074
secretion by cellGO:00329402480.073
regulation of kinase activityGO:00435491170.071
negative regulation of response to stimulusGO:00485851550.070
cellular ketone metabolic processGO:0042180510.068
localization of cellGO:00516742020.066
response to glucocorticoidGO:00513842230.066
protein phosphorylationGO:00064683450.064
negative regulation of signal transductionGO:0009968830.061
positive regulation of lymphocyte activationGO:0051251250.061
de novo posttranslational protein foldingGO:005108420.061
Mouse
nitrogen compound transportGO:00717052290.060
regulation of phosphate metabolic processGO:00192203490.059
cellular amino acid metabolic processGO:00065201070.058
single organism biosynthetic processGO:00447113420.057
immune responseGO:00069551040.057
immune effector processGO:0002252530.056
regulation of adaptive immune responseGO:000281980.056
amide transportGO:00428861050.055
unsaturated fatty acid biosynthetic processGO:0006636210.055
taxisGO:0042330670.055
regulation of apoptotic processGO:00429813350.055
positive regulation of cellular protein metabolic processGO:00322701670.055
positive regulation of cell communicationGO:00106472710.055
metal ion transportGO:00300012890.055
signal transduction by phosphorylationGO:00230141440.054
homeostasis of number of cellsGO:0048872100.054
apoptotic processGO:00069153810.054
regulation of programmed cell deathGO:00430673410.054
brain developmentGO:00074202470.054
divalent inorganic cation homeostasisGO:00725071650.052
positive regulation of phosphorylationGO:00423271770.052
positive regulation of chemokine productionGO:003272240.052
positive regulation of multicellular organismal processGO:00512403870.052
response to dexamethasoneGO:0071548490.052
negative regulation of neurogenesisGO:0050768780.051
response to interferon gammaGO:0034341200.051
single organism intracellular transportGO:19025821660.051
cell migrationGO:00164771970.050
leukocyte differentiationGO:0002521300.050
establishment of organelle localizationGO:0051656370.050
signal releaseGO:00230611450.050
regulation of cellular amino acid metabolic processGO:000652120.050
organelle organizationGO:00069962660.048
cell type specific apoptotic processGO:00972851340.048
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.048
regulation of homeostatic processGO:00328441010.045
positive regulation of cell motilityGO:2000147970.045
negative regulation of phosphate metabolic processGO:0045936800.045
cognitionGO:0050890920.045
positive regulation of phosphate metabolic processGO:00459372620.044
response to corticosteroidGO:00319602350.044
positive regulation of cellular amino acid metabolic processGO:004576410.044
lymphocyte activationGO:0046649430.043
hormone transportGO:00099141210.043
negative regulation of protein metabolic processGO:00512481140.043
cell projection organizationGO:00300303020.042
cellular component movementGO:00069282480.042
neuron projection developmentGO:00311752730.042
regulation of ion transportGO:00432692450.042
behaviorGO:00076102050.041
regulation of molecular functionGO:00650093980.041
single organism catabolic processGO:00447122830.041
regulation of peptide transportGO:0090087870.041
actin filament bundle assemblyGO:0051017190.040
central nervous system developmentGO:00074173110.040
regulation of erk1 and erk2 cascadeGO:0070372410.040
regulation of peptide secretionGO:0002791820.039
peptidyl tyrosine modificationGO:0018212720.039
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.039
regulation of secretion by cellGO:19035302080.038
locomotionGO:00400112370.038
cytoskeleton organizationGO:00070101110.037
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000282280.037
response to ketoneGO:19016541820.037
neurological system processGO:00508772190.037
positive regulation of antigen processing and presentationGO:000257910.036
regulation of cellular amine metabolic processGO:003323880.036
mapk cascadeGO:00001651400.036
nucleobase containing small molecule metabolic processGO:00550863160.036
regulation of cellular ketone metabolic processGO:0010565270.036
regulation of protein modification processGO:00313991940.035
regulation of cellular component biogenesisGO:0044087860.035
cellular amine metabolic processGO:0044106380.035
positive regulation of immune system processGO:0002684900.035
organelle localizationGO:0051640550.035
negative regulation of actin nucleationGO:005112610.034
negative regulation of cell communicationGO:00106481580.034
positive regulation of cell migrationGO:0030335960.034
negative regulation of phosphorus metabolic processGO:0010563800.034
peptide secretionGO:0002790860.034
positive regulation of leukocyte activationGO:0002696300.033
positive regulation of cellular amine metabolic processGO:003324030.033
regulation of cell differentiationGO:00455953200.033
olfactory learningGO:000835510.032
agingGO:00075682410.032
neuron apoptotic processGO:0051402880.032
regulation of transferase activityGO:00513381230.032
negative regulation of programmed cell deathGO:00430691830.032
positive regulation of kinase activityGO:0033674770.032
negative regulation of cell differentiationGO:0045596990.032
regulation of protein kinase activityGO:00458591050.031
positive regulation of protein phosphorylationGO:00019341350.031
positive regulation of transportGO:00510502450.031
regulation of cellular component organizationGO:00511283680.031
mitotic spindle organizationGO:000705220.031
neuron differentiationGO:00301823680.031
fatty acid derivative metabolic processGO:1901568380.031
prostaglandin metabolic processGO:0006693120.031
regulation of locomotionGO:00400121480.030
carbohydrate derivative catabolic processGO:19011361470.030
regulation of multicellular organismal developmentGO:20000263760.030
divalent metal ion transportGO:00708381320.030
arp2 3 complex mediated actin nucleationGO:003431420.029
regulation of cell developmentGO:00602842630.029
regulation of hormone levelsGO:00108171870.029
regulation of membrane potentialGO:00423911100.029
organic substance catabolic processGO:19015753160.029
regulation of system processGO:00440572080.028
endocytosisGO:0006897840.028
regulation of arp2 3 complex mediated actin nucleationGO:003431520.028
single organism cellular localizationGO:19025801020.028
negative regulation of homeostatic processGO:0032845470.028
secretionGO:00469033070.027
regulation of secretionGO:00510462240.027
regulation of synapse structure and activityGO:0050803210.027
biological adhesionGO:00226101100.027
positive regulation of cellular component biogenesisGO:0044089550.027
regulation of cellular localizationGO:00603412630.027
positive regulation of cell proliferationGO:00082842490.027
cellular response to oxygen containing compoundGO:19017013860.027
response to extracellular stimulusGO:00099913800.027
actin filament bundle organizationGO:0061572190.026
actin polymerization or depolymerizationGO:0008154140.026
leukocyte chemotaxisGO:0030595220.026
positive regulation of cellular component organizationGO:00511302000.026
lipid biosynthetic processGO:00086101280.026
negative regulation of peptide secretionGO:0002792300.026
regulation of neutrophil chemotaxisGO:009002250.026
intracellular transportGO:00469071850.026
positive regulation of catalytic activityGO:00430851840.026
response to toxic substanceGO:00096361330.026
exocytosisGO:0006887600.025
negative regulation of cell deathGO:00605482290.025
actin cytoskeleton organizationGO:0030036730.025
cell cell signalingGO:00072673350.025
axis specificationGO:000979840.025
negative regulation of cell proliferationGO:00082851190.025
positive regulation of molecular functionGO:00440932300.025
negative regulation of signalingGO:00230571570.025
cellular catabolic processGO:00442482950.025
ras protein signal transductionGO:0007265290.025
microtubule based processGO:0007017360.025
leukocyte mediated immunityGO:0002443280.025
fatty acid metabolic processGO:0006631990.025
negative regulation of metabolic processGO:00098923310.025
establishment of protein localizationGO:00451841410.024
organonitrogen compound catabolic processGO:19015651790.024
positive regulation of hydrolase activityGO:0051345860.024
stress activated mapk cascadeGO:0051403350.024
small molecule biosynthetic processGO:00442831240.024
regulation of cell migrationGO:00303341280.024
regulation of catalytic activityGO:00507903040.024
hemopoiesisGO:0030097340.024
positive regulation of protein kinase activityGO:0045860730.024
positive regulation of response to stimulusGO:00485842850.024
regulation of vesicle mediated transportGO:0060627810.023
regulation of actin filament based processGO:0032970420.023
positive regulation of protein metabolic processGO:00512471780.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
antigen processing and presentation of exogenous peptide antigenGO:000247810.023
Mouse
negative regulation of biosynthetic processGO:00098901680.023
regulation of lymphocyte activationGO:0051249340.022
nucleoside catabolic processGO:00091641260.022
neuron developmentGO:00486662860.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
regulation of antigen processing and presentationGO:000257710.022
spindle organizationGO:000705120.022
positive regulation of immunoglobulin productionGO:000263940.022
axon developmentGO:0061564960.022
monovalent inorganic cation transportGO:00156721720.022
organic cyclic compound catabolic processGO:19013611750.022
ribonucleotide metabolic processGO:00092592310.021
negative regulation of intracellular signal transductionGO:1902532380.021
response to campGO:0051591910.021
oxoacid metabolic processGO:00434362900.021
t cell differentiationGO:003021790.021
negative regulation of macromolecule metabolic processGO:00106052600.021
muscle system processGO:00030121150.021
sequestering of metal ionGO:005123890.021
head developmentGO:00603222470.021
regulation of b cell mediated immunityGO:000271220.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
activation of mapk activityGO:0000187330.020
embryonic pattern specificationGO:000988010.020
cell part morphogenesisGO:00329901230.020
positive regulation of peptide hormone secretionGO:0090277500.020
gtp metabolic processGO:0046039720.020
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.019
embryonic axis specificationGO:000057810.019
peptide transportGO:0015833970.019
response to cytokineGO:00340972150.019
regulation of protein metabolic processGO:00512462890.019
positive regulation of locomotionGO:00400171020.019
cytoplasmic transportGO:00164821150.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
purine ribonucleoside metabolic processGO:00461281680.019
response to osmotic stressGO:0006970420.019
hematopoietic progenitor cell differentiationGO:000224420.019
oxidation reduction processGO:00551143040.019
gtp catabolic processGO:0006184710.019
positive regulation of signalingGO:00230562700.019
purine ribonucleotide metabolic processGO:00091502270.018
positive regulation of cell differentiationGO:00455972170.018
regulation of lipid metabolic processGO:0019216680.018
cellular homeostasisGO:00197252520.018
regulation of immune responseGO:0050776550.018
negative regulation of nervous system developmentGO:0051961790.018
cytokine productionGO:0001816610.018
negative regulation of protein modification processGO:0031400520.018
myeloid leukocyte migrationGO:0097529200.017
macromolecule localizationGO:00330362520.017
cellular response to external stimulusGO:00714961180.017
negative regulation of transportGO:00510511360.017
cation homeostasisGO:00550801950.017
negative regulation of multicellular organismal processGO:00512412030.017
nucleoside triphosphate catabolic processGO:00091431230.017
regulation of cellular protein metabolic processGO:00322682670.017
regulation of intracellular transportGO:0032386650.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460130.017
positive regulation of reactive oxygen species metabolic processGO:2000379160.017
positive regulation of mapk cascadeGO:0043410920.017
negative regulation of phosphorylationGO:0042326570.017
guanosine containing compound metabolic processGO:1901068740.016
regulation of cellular response to stressGO:0080135490.016
regulation of metal ion transportGO:00109591180.016
catabolic processGO:00090563510.016
negative regulation of lymphocyte differentiationGO:004562020.016
regulation of cellular component movementGO:00512701500.016
olfactory behaviorGO:004204820.016
cellular macromolecule localizationGO:00707271220.016
organic acid metabolic processGO:00060822920.016
lymphocyte mediated immunityGO:0002449140.016
cellular response to hormone stimulusGO:00328702470.016
regulation of smooth muscle cell proliferationGO:0048660750.016
regulation of mapk cascadeGO:00434081160.016
cell morphogenesis involved in differentiationGO:00009041190.016
organophosphate catabolic processGO:00464341480.016
regulation of nervous system developmentGO:00519602640.016
t cell selectionGO:004505810.016
cellular response to starvationGO:0009267270.016
cell morphogenesisGO:00009021420.016
negative regulation of protein phosphorylationGO:0001933440.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
regulation of cytokine productionGO:0001817560.016
maintenance of locationGO:0051235170.016
salivary gland developmentGO:000743130.016
homeostatic processGO:00425923310.016
response to peptideGO:19016522920.016
purine containing compound catabolic processGO:00725231380.016
regulation of calcium ion transportGO:0051924770.015
production of molecular mediator of immune responseGO:000244080.015
reactive oxygen species metabolic processGO:0072593370.015
granulocyte migrationGO:0097530160.015
multicellular organismal reproductive processGO:00486092330.015
regulation of hormone secretionGO:00468831060.015
regulation of immunoglobulin mediated immune responseGO:000288920.015
positive regulation of protein modification processGO:00314011420.015
myeloid leukocyte cytokine productionGO:006108210.015
cellular response to insulin stimulusGO:0032869810.015
ribose phosphate metabolic processGO:00196932350.015
reactive oxygen species biosynthetic processGO:190340980.015
positive regulation of phosphorus metabolic processGO:00105622620.014
reproductionGO:00000032450.014
negative regulation of cellular protein metabolic processGO:00322691060.014
cell junction maintenanceGO:003433110.014
response to vitaminGO:00332731310.014
rna metabolic processGO:00160704060.014
organ regenerationGO:00311001010.014
inorganic anion transportGO:0015698410.014
divalent inorganic cation transportGO:00725111340.014
positive regulation of immune effector processGO:0002699190.014
response to axon injuryGO:0048678590.014
regulation of cell cell adhesionGO:0022407140.014
reactive nitrogen species metabolic processGO:200105710.014
fatty acid biosynthetic processGO:0006633330.013
membrane fusionGO:0061025260.013
phagocytosisGO:0006909170.013
cell motilityGO:00488702020.013
actin filament organizationGO:0007015420.013
anterior posterior pattern specificationGO:000995210.013
cellular calcium ion homeostasisGO:00068741600.013
positive regulation of signal transductionGO:00099671750.013
positive regulation of apoptotic processGO:00430651540.013
defense response to gram positive bacteriumGO:005083020.013
actin nucleationGO:004501020.013
purine ribonucleotide catabolic processGO:00091541360.013
platelet aggregationGO:007052740.013
cellular response to cytokine stimulusGO:00713451270.013
defense response to gram negative bacteriumGO:005082930.013
response to decreased oxygen levelsGO:00362932370.013
lymphocyte differentiationGO:0030098100.013
carbohydrate metabolic processGO:00059751300.013
calcium ion homeostasisGO:00550741620.013
positive regulation of hormone secretionGO:0046887650.013
calcium ion transportGO:00068161310.013
response to hydrogen peroxideGO:0042542890.012
single organism cell adhesionGO:0098602460.012
positive regulation of intracellular protein transportGO:0090316200.012
positive regulation of developmental processGO:00510942830.012
nucleotide metabolic processGO:00091172790.012
proximal distal pattern formationGO:000995410.012
rho protein signal transductionGO:0007266110.012
response to growth factorGO:00708481890.012
response to inorganic substanceGO:00100353770.012
immune system developmentGO:0002520410.012
triglyceride homeostasisGO:007032820.012
adherens junction maintenanceGO:003433410.012
transcription dna templatedGO:00063513770.012
regulation of release of sequestered calcium ion into cytosolGO:0051279180.012
regulation of neuron projection developmentGO:00109751610.012
regulation of leukocyte migrationGO:0002685240.012
negative regulation of cellular metabolic processGO:00313242810.012
positive regulation of leukocyte proliferationGO:0070665200.012
nucleotide catabolic processGO:00091661390.012
chemical homeostasisGO:00488782920.012
positive regulation of granulocyte chemotaxisGO:007162460.012
regulation of signal transductionGO:00099663180.012
actin filament depolymerizationGO:003004230.012
negative regulation of lymphocyte apoptotic processGO:007022910.012
regulation of anatomical structure sizeGO:00900661350.012
protein heterooligomerizationGO:0051291890.012
proteolysis involved in cellular protein catabolic processGO:0051603190.012
regulation of intracellular signal transductionGO:19025312180.011
positive regulation of organelle organizationGO:0010638480.011
regulation of cell projection organizationGO:00313441750.011
response to insulinGO:00328681330.011
monocarboxylic acid metabolic processGO:00327871520.011
peptidyl tyrosine phosphorylationGO:0018108720.011
negative regulation of gene expressionGO:00106291990.011
positive regulation of cell deathGO:00109421840.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
hormone secretionGO:00468791150.011
positive regulation of gene expressionGO:00106282440.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
positive regulation of programmed cell deathGO:00430681570.011
axonogenesisGO:0007409710.011
cell cycleGO:00070491010.011
carbohydrate derivative metabolic processGO:19011353460.011
chemosensory behaviorGO:000763520.011
single organism behaviorGO:00447081300.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
amine metabolic processGO:0009308380.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
regulation of leukocyte differentiationGO:1902105200.011
nucleic acid templated transcriptionGO:00976593790.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
response to peptide hormoneGO:00434342780.011
regulation of erythrocyte aggregationGO:003411810.011
purine containing compound metabolic processGO:00725212530.011
cellular response to abiotic stimulusGO:0071214850.011
positive regulation of cell activationGO:0050867340.011
cellular response to lipidGO:00713962010.011
alcohol metabolic processGO:0006066770.010
cell chemotaxisGO:0060326310.010
phospholipid metabolic processGO:0006644610.010
positive regulation of t cell proliferationGO:0042102120.010
cellular chemical homeostasisGO:00550822470.010
protein transportGO:00150311320.010
lipid storageGO:001991510.010
antibiotic transportGO:004289120.010
leukocyte homeostasisGO:000177670.010
microtubule organizing center organizationGO:003102310.010
mitotic cell cycleGO:0000278490.010

RT1-DMb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
primary immunodeficiency diseaseDOID:61200.018
immune system diseaseDOID:291400.018