Rattus norvegicus

0 known processes

Trex2

three prime repair exonuclease 2

(Aliases: RGD1562245)

Trex2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cell communicationGO:00106472710.130
response to inorganic substanceGO:00100353770.122
regulation of phosphate metabolic processGO:00192203490.116
cellular component biogenesisGO:00440853680.096
response to acid chemicalGO:00011012220.093
regulation of cell proliferationGO:00421273590.093
wound healingGO:00420601220.083
single organism reproductive processGO:00447022970.081
positive regulation of cell proliferationGO:00082842490.080
response to glucocorticoidGO:00513842230.078
response to extracellular stimulusGO:00099913800.070
regulation of cell differentiationGO:00455953200.065
regulation of apoptotic processGO:00429813350.064
signal transduction by phosphorylationGO:00230141440.063
macromolecular complex subunit organizationGO:00439333390.060
regulation of system processGO:00440572080.058
regulation of molecular functionGO:00650093980.058
response to oxygen levelsGO:00704822650.058
response to nutrient levelsGO:00316673700.057
regulation of programmed cell deathGO:00430673410.057
intracellular signal transductionGO:00355563140.056
positive regulation of developmental processGO:00510942830.054
anatomical structure morphogenesisGO:00096532980.054
cellular response to oxygen containing compoundGO:19017013860.053
reproductive processGO:00224143720.050
tissue developmentGO:00098882520.049
metal ion transportGO:00300012890.049
sensory perceptionGO:00076001010.048
response to carbohydrateGO:00097431830.047
neurological system processGO:00508772190.042
circulatory system processGO:00030131830.042
cellular component assemblyGO:00226073600.041
tongue morphogenesisGO:004358730.041
negative regulation of transportGO:00510511360.041
cellular response to lipidGO:00713962010.041
regulation of protein localizationGO:0032880810.041
response to estrogenGO:00436272320.040
regulation of intracellular signal transductionGO:19025312180.040
regulation of protein metabolic processGO:00512462890.040
positive regulation of phosphorylationGO:00423271770.039
response to nutrientGO:00075842480.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
response to estradiolGO:00323551640.038
small molecule biosynthetic processGO:00442831240.038
response to hexoseGO:00097461440.038
agingGO:00075682410.038
amine metabolic processGO:0009308380.037
rhythmic processGO:00485111560.037
neuron projection developmentGO:00311752730.037
positive regulation of multicellular organismal processGO:00512403870.037
negative regulation of apoptotic processGO:00430661810.036
multicellular organismal reproductive processGO:00486092330.036
regulation of phosphorylationGO:00423252480.036
cellular amine metabolic processGO:0044106380.036
response to woundingGO:00096112540.036
response to corticosteroidGO:00319602350.036
developmental process involved in reproductionGO:00030061590.036
positive regulation of molecular functionGO:00440932300.036
positive regulation of signalingGO:00230562700.035
macromolecular complex assemblyGO:00650032730.035
response to oxidative stressGO:00069791860.035
regulation of catalytic activityGO:00507903040.035
wnt signaling pathway planar cell polarity pathwayGO:006007120.035
negative regulation of cell proliferationGO:00082851190.035
regulation of phosphorus metabolic processGO:00511743490.035
response to decreased oxygen levelsGO:00362932370.033
negative regulation of macromolecule metabolic processGO:00106052600.033
cellular response to stressGO:00335542690.032
regulation of signal transductionGO:00099663180.032
protein complex biogenesisGO:00702712630.032
negative regulation of programmed cell deathGO:00430691830.032
multicellular organism reproductionGO:00325042330.032
positive regulation of phosphate metabolic processGO:00459372620.032
regulation of cellular component organizationGO:00511283680.031
negative regulation of cell communicationGO:00106481580.030
cellular response to steroid hormone stimulusGO:0071383930.030
cellular response to organic cyclic compoundGO:00714072020.030
positive regulation of phosphorus metabolic processGO:00105622620.029
positive regulation of catalytic activityGO:00430851840.029
protein localizationGO:00081041910.029
positive regulation of macromolecule biosynthetic processGO:00105572470.029
ion transmembrane transportGO:00342203650.029
negative regulation of gene expressionGO:00106291990.029
positive regulation of protein phosphorylationGO:00019341350.028
ion homeostasisGO:00508012120.028
head developmentGO:00603222470.028
protein complex subunit organizationGO:00718223020.028
homeostatic processGO:00425923310.028
cellular ketone metabolic processGO:0042180510.028
inorganic ion transmembrane transportGO:00986602290.028
regulation of protein phosphorylationGO:00019321830.028
enzyme linked receptor protein signaling pathwayGO:00071671160.028
circulatory system developmentGO:00723591340.028
blood circulationGO:00080151830.028
monovalent inorganic cation transportGO:00156721720.027
positive regulation of gene expressionGO:00106282440.027
regulation of multicellular organismal developmentGO:20000263760.026
regulation of cellular localizationGO:00603412630.026
reproductive system developmentGO:00614581280.026
cell projection organizationGO:00300303020.026
regulation of establishment of planar polarityGO:009017520.026
regulation of cellular protein metabolic processGO:00322682670.026
positive regulation of response to stimulusGO:00485842850.026
secretionGO:00469033070.026
reproductive structure developmentGO:00486081280.026
organic acid metabolic processGO:00060822920.026
multi organism reproductive processGO:00447032620.026
ribonucleoside metabolic processGO:00091191740.026
positive regulation of transportGO:00510502450.025
fibrinolysisGO:004273020.025
carboxylic acid biosynthetic processGO:0046394830.025
neuron differentiationGO:00301823680.025
protein complex assemblyGO:00064612630.025
carboxylic acid metabolic processGO:00197522890.025
chemical homeostasisGO:00488782920.025
response to retinoic acidGO:0032526630.025
cellular response to glucocorticoid stimulusGO:0071385680.025
response to growth factorGO:00708481890.025
regulation of protein modification processGO:00313991940.025
establishment of tissue polarityGO:000716420.025
regulation of cellular amino acid metabolic processGO:000652120.025
cellular chemical homeostasisGO:00550822470.025
programmed cell deathGO:00125013920.024
cation transportGO:00068123820.024
negative regulation of cell deathGO:00605482290.024
ribose phosphate metabolic processGO:00196932350.024
rna metabolic processGO:00160704060.024
protein oligomerizationGO:00512591910.024
single organism catabolic processGO:00447122830.024
ovulation cycle processGO:0022602500.023
regulation of cellular amine metabolic processGO:003323880.023
regulation of anatomical structure sizeGO:00900661350.023
alcohol metabolic processGO:0006066770.023
heart processGO:0003015570.023
regulation of ion transportGO:00432692450.023
single organism biosynthetic processGO:00447113420.022
cellular response to acid chemicalGO:0071229750.022
response to glucoseGO:00097491360.022
brain developmentGO:00074202470.022
regulation of neuron projection developmentGO:00109751610.022
positive regulation of cell deathGO:00109421840.022
regulation of mapk cascadeGO:00434081160.022
developmental growthGO:00485891000.022
response to metal ionGO:00100382530.022
response to ketoneGO:19016541820.022
cellular nitrogen compound catabolic processGO:00442701630.022
Human
synaptic transmissionGO:00072682350.022
blood vessel developmentGO:0001568690.022
nucleotide metabolic processGO:00091172790.022
proteolysisGO:00065081750.021
response to reactive oxygen speciesGO:00003021200.021
negative regulation of metabolic processGO:00098923310.021
positive regulation of programmed cell deathGO:00430681570.021
kidney developmentGO:0001822670.021
cytosolic calcium ion homeostasisGO:00514801400.021
apoptotic processGO:00069153810.021
cellular response to endogenous stimulusGO:00714953770.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
reproductionGO:00000032450.021
nucleoside phosphate metabolic processGO:00067532830.021
response to monosaccharideGO:00342841590.020
cell cell signalingGO:00072673350.020
regulation of anatomical structure morphogenesisGO:00226031410.020
regulation of cellular ketone metabolic processGO:0010565270.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
vascular process in circulatory systemGO:0003018960.020
organ regenerationGO:00311001010.020
positive regulation of cellular biosynthetic processGO:00313282950.020
muscle system processGO:00030121150.020
regulation of hydrolase activityGO:00513361430.020
action potentialGO:0001508540.020
regulation of rna biosynthetic processGO:20011413810.019
urogenital system developmentGO:0001655780.019
heart morphogenesisGO:000300730.019
vasoconstrictionGO:0042310540.019
nucleobase containing small molecule metabolic processGO:00550863160.019
regulation of kinase activityGO:00435491170.019
ribonucleotide metabolic processGO:00092592310.019
hormone secretionGO:00468791150.019
regulation of protein kinase activityGO:00458591050.019
positive regulation of protein metabolic processGO:00512471780.019
sexual reproductionGO:00199531480.019
positive regulation of biosynthetic processGO:00098913190.019
cellular response to nitrogen compoundGO:19016992100.019
negative regulation of protein metabolic processGO:00512481140.019
regulation of neuron differentiationGO:00456642080.019
cardiovascular system developmentGO:00723581340.019
organophosphate catabolic processGO:00464341480.019
cellular calcium ion homeostasisGO:00068741600.019
negative regulation of cellular metabolic processGO:00313242810.018
negative regulation of signalingGO:00230571570.018
ovulation cycleGO:0042698670.018
response to peptideGO:19016522920.018
regulation of transferase activityGO:00513381230.018
divalent inorganic cation homeostasisGO:00725071650.018
carbohydrate derivative metabolic processGO:19011353460.018
embryonic hindlimb morphogenesisGO:003511620.018
organonitrogen compound catabolic processGO:19015651790.018
regulation of nervous system developmentGO:00519602640.018
smooth muscle cell proliferationGO:0048659770.018
purine containing compound metabolic processGO:00725212530.018
regulation of secretion by cellGO:19035302080.018
glycosyl compound metabolic processGO:19016571820.018
neuron developmentGO:00486662860.018
response to hypoxiaGO:00016662310.018
cellular response to hormone stimulusGO:00328702470.018
gland developmentGO:00487321550.018
positive regulation of apoptotic processGO:00430651540.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
actin filament based processGO:0030029860.018
cellular response to peptideGO:19016531330.017
organophosphate metabolic processGO:00196373700.017
immune system processGO:00023762040.017
ras protein signal transductionGO:0007265290.017
metestrusGO:006021010.017
regulation of cell projection organizationGO:00313441750.017
regulation of neurogenesisGO:00507672470.017
response to vitaminGO:00332731310.017
secretion by cellGO:00329402480.017
heart contractionGO:0060047570.017
positive regulation of signal transductionGO:00099671750.017
epithelial cell differentiationGO:0030855710.017
response to alkaloidGO:00432791320.017
regulation of smooth muscle cell proliferationGO:0048660750.017
epithelium developmentGO:0060429960.017
cellular amino acid metabolic processGO:00065201070.017
gamete generationGO:00072761240.017
regulation of blood vessel sizeGO:0050880890.017
cellular catabolic processGO:00442482950.017
Human
organic substance catabolic processGO:19015753160.017
Human
cytoskeleton organizationGO:00070101110.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
macromolecule localizationGO:00330362520.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
regulation of membrane potentialGO:00423911100.017
positive regulation of ion transportGO:0043270940.016
regulation of sodium ion transmembrane transporter activityGO:200064940.016
negative regulation of molecular functionGO:00440921330.016
ribonucleoside catabolic processGO:00424541260.016
positive regulation of cellular amine metabolic processGO:003324030.016
epithelial cell proliferationGO:0050673540.016
purine ribonucleotide metabolic processGO:00091502270.016
positive regulation of smooth muscle cell proliferationGO:0048661510.016
growthGO:00400071650.016
nucleobase containing compound catabolic processGO:00346551520.016
Human
single organism organelle organizationGO:19025891800.016
small gtpase mediated signal transductionGO:0007264360.016
regulation of ion transmembrane transporter activityGO:0032412480.016
positive regulation of cellular amino acid metabolic processGO:004576410.015
purine ribonucleoside metabolic processGO:00461281680.015
sex differentiationGO:00075481130.015
organelle organizationGO:00069962660.015
purine ribonucleotide catabolic processGO:00091541360.015
purine nucleotide metabolic processGO:00061632290.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
regulation of transcription dna templatedGO:00063553740.015
non canonical wnt signaling pathwayGO:003556730.015
spermatogenesisGO:0007283990.015
positive regulation of mapk cascadeGO:0043410920.015
organic cyclic compound catabolic processGO:19013611750.015
Human
regulation of metal ion transportGO:00109591180.015
gastrulationGO:000736920.015
positive regulation of protein modification processGO:00314011420.015
response to peptide hormoneGO:00434342780.015
negative regulation of developmental processGO:00510931250.015
positive regulation of rna biosynthetic processGO:19026801970.014
oxoacid metabolic processGO:00434362900.014
transcription from rna polymerase ii promoterGO:00063662520.014
monocarboxylic acid biosynthetic processGO:0072330480.014
behaviorGO:00076102050.014
regulation of plasminogen activationGO:001075520.014
establishment of protein localizationGO:00451841410.014
organic hydroxy compound metabolic processGO:19016151150.014
cellular homeostasisGO:00197252520.014
purine nucleoside metabolic processGO:00422781690.014
regulation of cell developmentGO:00602842630.014
cellular response to corticosteroid stimulusGO:0071384690.014
axis specificationGO:000979840.014
inorganic cation transmembrane transportGO:00986622020.014
mapk cascadeGO:00001651400.014
actin cytoskeleton organizationGO:0030036730.013
regulation of blood pressureGO:0008217830.013
hematopoietic progenitor cell differentiationGO:000224420.013
regulation of vasoconstrictionGO:0019229440.013
rna biosynthetic processGO:00327743800.013
regulation of blood circulationGO:19035221100.013
single organism intracellular transportGO:19025821660.013
mesoderm developmentGO:000749820.013
neuronal action potentialGO:0019228350.013
glucose homeostasisGO:0042593750.013
regulation of rna metabolic processGO:00512523910.013
gonad developmentGO:00084061040.013
insulin like growth factor receptor signaling pathwayGO:004800930.013
regulation of transporter activityGO:0032409500.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
regulation of epithelial cell proliferationGO:0050678490.013
metal ion homeostasisGO:00550651860.013
regulation of cell cycleGO:0051726730.013
regulation of transmembrane transportGO:00347621220.013
cellular response to alcoholGO:0097306870.013
negative regulation of cellular protein metabolic processGO:00322691060.013
vasculature developmentGO:0001944700.013
calcium ion homeostasisGO:00550741620.012
regulation of ion transmembrane transportGO:00347651210.012
regulation of body fluid levelsGO:0050878900.012
nucleoside metabolic processGO:00091161790.012
positive regulation of nervous system developmentGO:00519621780.012
establishment of planar polarityGO:000173610.012
development of primary sexual characteristicsGO:00451371070.012
positive regulation of blood coagulationGO:003019440.012
negative regulation of ion transportGO:0043271510.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
negative regulation of fibrinolysisGO:005191820.012
nucleic acid templated transcriptionGO:00976593790.012
positive regulation of neuron differentiationGO:00456661260.012
response to molecule of bacterial originGO:00022371940.012
positive regulation of cellular protein metabolic processGO:00322701670.012
lipid metabolic processGO:00066292830.012
regulation of cell projection sizeGO:003253610.012
cellular metal ion homeostasisGO:00068751720.012
positive regulation of cell projection organizationGO:00313461110.012
organophosphate biosynthetic processGO:00904071430.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
central nervous system developmentGO:00074173110.011
organic acid biosynthetic processGO:0016053830.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
cellular response to growth factor stimulusGO:00713631620.011
muscle contractionGO:0006936880.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
negative regulation of multicellular organismal processGO:00512412030.011
positive regulation of transferase activityGO:0051347810.011
muscle cell proliferationGO:0033002840.011
cellular response to oxidative stressGO:0034599760.011
cation transmembrane transportGO:00986552630.011
cellular response to metal ionGO:0071248550.011
negative regulation of cell differentiationGO:0045596990.011
protein transportGO:00150311320.011
negative regulation of biosynthetic processGO:00098901680.011
negative regulation of cellular biosynthetic processGO:00313271610.011
response to transition metal nanoparticleGO:19902671220.011
cellular ion homeostasisGO:00068731840.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
positive regulation of rna metabolic processGO:00512542030.011
morphogenesis of a polarized epitheliumGO:000173810.011
cellular component morphogenesisGO:00329891550.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
cellular cation homeostasisGO:00300031800.011
cytoplasmic transportGO:00164821150.011
cellular lipid metabolic processGO:00442552080.011
glycosyl compound catabolic processGO:19016581260.011
liver developmentGO:0001889900.011
male gamete generationGO:0048232990.011
regulation of secretionGO:00510462240.010
nucleoside triphosphate catabolic processGO:00091431230.010
regulation of nucleotide metabolic processGO:00061401170.010
cation homeostasisGO:00550801950.010
regulation of cell motilityGO:20001451310.010
catabolic processGO:00090563510.010
Human
ribonucleoside triphosphate metabolic processGO:00091991410.010
fatty acid biosynthetic processGO:0006633330.010
regulation of tube sizeGO:0035150890.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
regulation of muscle system processGO:0090257790.010
positive regulation of cellular component organizationGO:00511302000.010
positive regulation of intracellular signal transductionGO:19025331380.010
plasminogen activationGO:003163920.010
protein phosphorylationGO:00064683450.010
response to nicotineGO:0035094510.010
forebrain developmentGO:0030900980.010
regulation of homeostatic processGO:00328441010.010

Trex2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
musculoskeletal system diseaseDOID:1700.012
nervous system diseaseDOID:86300.010