IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Atp6v1b1

ATPase, H transporting, lysosomal V1 subunit B1

Ensembl: ENSRNOG00000013573
Entrez: 312488
RGD: 1310619
UniProtKB: D3ZZS8

Process Predictions
Disease Predictions

Atp6v1b1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neuron differentiation	GO:0030182	368	0.192
cation transport	GO:0006812	382	0.131	Human
inorganic cation transmembrane transport	GO:0098662	202	0.102
regulation of cell differentiation	GO:0045595	320	0.099
intracellular signal transduction	GO:0035556	314	0.097
inorganic ion transmembrane transport	GO:0098660	229	0.085
regulation of cellular component organization	GO:0051128	368	0.085
cation transmembrane transport	GO:0098655	263	0.083
neuron development	GO:0048666	286	0.082
cell projection organization	GO:0030030	302	0.082
neuron projection development	GO:0031175	273	0.069
regulation of cell proliferation	GO:0042127	359	0.067
transmembrane transport	GO:0055085	412	0.067
oxoacid metabolic process	GO:0043436	290	0.066
regulation of cell development	GO:0060284	263	0.064
cellular component biogenesis	GO:0044085	368	0.063
cell projection morphogenesis	GO:0048858	123	0.061
regulation of neuron projection development	GO:0010975	161	0.061
sodium ion transport	GO:0006814	82	0.061
ion transmembrane transport	GO:0034220	365	0.060
tissue development	GO:0009888	252	0.058
positive regulation of phosphate metabolic process	GO:0045937	262	0.056
regulation of molecular function	GO:0065009	398	0.056
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.056
regulation of transcription dna templated	GO:0006355	374	0.053
regulation of neurogenesis	GO:0050767	247	0.052
regulation of nucleic acid templated transcription	GO:1903506	380	0.052
cellular response to stress	GO:0033554	269	0.051
cell cell signaling	GO:0007267	335	0.050
response to external biotic stimulus	GO:0043207	221	0.050
macromolecule localization	GO:0033036	252	0.049
anatomical structure morphogenesis	GO:0009653	298	0.048	Human
programmed cell death	GO:0012501	392	0.048
cellular component assembly	GO:0022607	360	0.047
protein localization	GO:0008104	191	0.047
organic acid metabolic process	GO:0006082	292	0.047
carboxylic acid metabolic process	GO:0019752	289	0.046
regulation of phosphate metabolic process	GO:0019220	349	0.045
regulation of phosphorus metabolic process	GO:0051174	349	0.044
positive regulation of cellular component organization	GO:0051130	200	0.044
positive regulation of phosphorus metabolic process	GO:0010562	262	0.044
protein phosphorylation	GO:0006468	345	0.044
organelle organization	GO:0006996	266	0.043
regulation of multicellular organismal development	GO:2000026	376	0.043
cellular component movement	GO:0006928	248	0.042
apoptotic process	GO:0006915	381	0.042
regulation of cellular amine metabolic process	GO:0033238	8	0.042
rna metabolic process	GO:0016070	406	0.042
establishment of protein localization	GO:0045184	141	0.042
response to wounding	GO:0009611	254	0.041
regulation of apoptotic process	GO:0042981	335	0.039
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.039
cell part morphogenesis	GO:0032990	123	0.037
regulation of neuron differentiation	GO:0045664	208	0.037
regulation of phosphorylation	GO:0042325	248	0.037
cellular homeostasis	GO:0019725	252	0.037
regulation of nervous system development	GO:0051960	264	0.037
divalent metal ion transport	GO:0070838	132	0.036
cellular amino acid metabolic process	GO:0006520	107	0.036
regulation of response to stress	GO:0080134	126	0.035
negative regulation of cell death	GO:0060548	229	0.035
response to estradiol	GO:0032355	164	0.034
cellular macromolecule localization	GO:0070727	122	0.034
single organism biosynthetic process	GO:0044711	342	0.034
response to inorganic substance	GO:0010035	377	0.034
reproductive structure development	GO:0048608	128	0.034
single organism reproductive process	GO:0044702	297	0.034
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.034
positive regulation of cellular biosynthetic process	GO:0031328	295	0.033
nucleobase containing small molecule metabolic process	GO:0055086	316	0.033
regulation of rna metabolic process	GO:0051252	391	0.033
homeostatic process	GO:0042592	331	0.033	Human
response to estrogen	GO:0043627	232	0.032
cell morphogenesis involved in differentiation	GO:0000904	119	0.032
regulation of cellular protein metabolic process	GO:0032268	267	0.032
cellular chemical homeostasis	GO:0055082	247	0.032
metal ion transport	GO:0030001	289	0.032
cell morphogenesis	GO:0000902	142	0.032
circulatory system process	GO:0003013	183	0.031
cellular amine metabolic process	GO:0044106	38	0.031
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.031
response to peptide	GO:1901652	292	0.031
regulation of cellular localization	GO:0060341	263	0.030
locomotion	GO:0040011	237	0.030
biological adhesion	GO:0022610	110	0.030
rna biosynthetic process	GO:0032774	380	0.030
regulation of cellular amino acid metabolic process	GO:0006521	2	0.030
amine metabolic process	GO:0009308	38	0.029
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.029
regulation of protein modification process	GO:0031399	194	0.029
intracellular transport	GO:0046907	185	0.029
positive regulation of molecular function	GO:0044093	230	0.029
organic anion transport	GO:0015711	132	0.028
positive regulation of biosynthetic process	GO:0009891	319	0.028
neuron projection morphogenesis	GO:0048812	122	0.028
regulation of protein metabolic process	GO:0051246	289	0.028
regulation of rna biosynthetic process	GO:2001141	381	0.028
positive regulation of cell proliferation	GO:0008284	249	0.027
proteolysis	GO:0006508	175	0.027
dendrite development	GO:0016358	72	0.027
single organism intracellular transport	GO:1902582	166	0.026
response to mechanical stimulus	GO:0009612	134	0.026
positive regulation of transport	GO:0051050	245	0.026
regulation of cell projection organization	GO:0031344	175	0.026
nucleic acid templated transcription	GO:0097659	379	0.026
regulation of catalytic activity	GO:0050790	304	0.026
hormone secretion	GO:0046879	115	0.026
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.026
membrane organization	GO:0061024	94	0.026
brain development	GO:0007420	247	0.026
transcription dna templated	GO:0006351	377	0.025
cellular ketone metabolic process	GO:0042180	51	0.025
single organism cellular localization	GO:1902580	102	0.025
positive regulation of phosphorylation	GO:0042327	177	0.025
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.025
regulation of cell morphogenesis	GO:0022604	77	0.025
negative regulation of macromolecule metabolic process	GO:0010605	260	0.025
anion transport	GO:0006820	178	0.025
negative regulation of metabolic process	GO:0009892	331	0.025
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.024
negative regulation of cellular biosynthetic process	GO:0031327	161	0.024
regulation of signal transduction	GO:0009966	318	0.024
response to nutrient levels	GO:0031667	370	0.024
negative regulation of programmed cell death	GO:0043069	183	0.024
response to other organism	GO:0051707	220	0.024
regulation of intracellular signal transduction	GO:1902531	218	0.024
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.024
reproductive system development	GO:0061458	128	0.023
positive regulation of developmental process	GO:0051094	283	0.023
response to peptide hormone	GO:0043434	278	0.023
cellular response to oxygen containing compound	GO:1901701	386	0.023
reproductive process	GO:0022414	372	0.023
cellular component morphogenesis	GO:0032989	155	0.023
positive regulation of transcription dna templated	GO:0045893	197	0.023
multicellular organism reproduction	GO:0032504	233	0.022
positive regulation of response to stimulus	GO:0048584	285	0.022
protein complex subunit organization	GO:0071822	302	0.022
positive regulation of gene expression	GO:0010628	244	0.022
protein complex assembly	GO:0006461	263	0.022
positive regulation of programmed cell death	GO:0043068	157	0.022
catabolic process	GO:0009056	351	0.022
positive regulation of protein metabolic process	GO:0051247	178	0.022
protein complex biogenesis	GO:0070271	263	0.022
positive regulation of protein modification process	GO:0031401	142	0.022
negative regulation of response to stimulus	GO:0048585	155	0.022
divalent inorganic cation transport	GO:0072511	134	0.022
negative regulation of developmental process	GO:0051093	125	0.021
protein transport	GO:0015031	132	0.021
negative regulation of signaling	GO:0023057	157	0.021
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.021
central nervous system development	GO:0007417	311	0.021
negative regulation of cell differentiation	GO:0045596	99	0.021
response to oxygen levels	GO:0070482	265	0.021
carbohydrate derivative biosynthetic process	GO:1901137	124	0.021
response to nutrient	GO:0007584	248	0.021
calcium ion transmembrane transport	GO:0070588	70	0.021
aromatic compound catabolic process	GO:0019439	168	0.021
neurological system process	GO:0050877	219	0.021	Human
synaptic transmission	GO:0007268	235	0.021
cell type specific apoptotic process	GO:0097285	134	0.021
monovalent inorganic cation transport	GO:0015672	172	0.021	Human
chemical homeostasis	GO:0048878	292	0.021	Human
gonad development	GO:0008406	104	0.020
cellular response to peptide hormone stimulus	GO:0071375	120	0.020
positive regulation of multicellular organismal process	GO:0051240	387	0.020
negative regulation of transcription dna templated	GO:0045892	116	0.020
response to hypoxia	GO:0001666	231	0.020
localization of cell	GO:0051674	202	0.020
positive regulation of cellular amine metabolic process	GO:0033240	3	0.020
positive regulation of signal transduction	GO:0009967	175	0.020
response to biotic stimulus	GO:0009607	226	0.020
regulation of programmed cell death	GO:0043067	341	0.020
cellular response to nitrogen compound	GO:1901699	210	0.020
positive regulation of catalytic activity	GO:0043085	184	0.020
regulation of dendrite development	GO:0050773	59	0.019
s shaped body morphogenesis	GO:0072050	2	0.019
single organism organelle organization	GO:1902589	180	0.019
regulation of anatomical structure size	GO:0090066	135	0.019
regulation of protein phosphorylation	GO:0001932	183	0.019
head development	GO:0060322	247	0.019
positive regulation of cell development	GO:0010720	176	0.019
developmental process involved in reproduction	GO:0003006	159	0.019
regulation of establishment of planar polarity	GO:0090175	2	0.019
negative regulation of apoptotic process	GO:0043066	181	0.019
regulation of cellular ketone metabolic process	GO:0010565	27	0.018
negative regulation of gene expression	GO:0010629	199	0.018
negative regulation of cell communication	GO:0010648	158	0.018
calcium ion transport	GO:0006816	131	0.018
peptidyl amino acid modification	GO:0018193	126	0.018
regulation of establishment of protein localization	GO:0070201	69	0.018
nucleotide metabolic process	GO:0009117	279	0.018
inflammatory response	GO:0006954	150	0.018
response to toxic substance	GO:0009636	133	0.018
positive regulation of rna metabolic process	GO:0051254	203	0.018
positive regulation of cellular protein metabolic process	GO:0032270	167	0.018
regulation of immune system process	GO:0002682	123	0.018
transcription from rna polymerase ii promoter	GO:0006366	252	0.017
cellular nitrogen compound catabolic process	GO:0044270	163	0.017
single organism membrane organization	GO:0044802	74	0.017
response to acid chemical	GO:0001101	222	0.017
response to corticosteroid	GO:0031960	235	0.017
regulation of protein localization	GO:0032880	81	0.017
organophosphate metabolic process	GO:0019637	370	0.017
sex differentiation	GO:0007548	113	0.017
negative regulation of cellular metabolic process	GO:0031324	281	0.017
sensory organ development	GO:0007423	74	0.017	Human
aging	GO:0007568	241	0.017
cell activation	GO:0001775	97	0.017
cell adhesion	GO:0007155	110	0.017
purine containing compound biosynthetic process	GO:0072522	85	0.017
negative regulation of rna metabolic process	GO:0051253	123	0.017
embryo development	GO:0009790	49	0.017	Human
positive regulation of signaling	GO:0023056	270	0.016
axis specification	GO:0009798	4	0.016
liver development	GO:0001889	90	0.016
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.016
purine ribonucleotide metabolic process	GO:0009150	227	0.016
developmental growth	GO:0048589	100	0.016
cellular protein localization	GO:0034613	122	0.016
reproduction	GO:0000003	245	0.016
regulation of blood circulation	GO:1903522	110	0.016
macromolecular complex assembly	GO:0065003	273	0.016
secretion	GO:0046903	307	0.016
response to oxidative stress	GO:0006979	186	0.016
cell cycle	GO:0007049	101	0.016
nucleoside phosphate biosynthetic process	GO:1901293	102	0.016
wnt signaling pathway planar cell polarity pathway	GO:0060071	2	0.016
response to bacterium	GO:0009617	200	0.016
cellular response to lipid	GO:0071396	201	0.016
positive regulation of intracellular signal transduction	GO:1902533	138	0.015
defense response	GO:0006952	194	0.015
cellular response to abiotic stimulus	GO:0071214	85	0.015
negative regulation of signal transduction	GO:0009968	83	0.015
cell migration	GO:0016477	197	0.015
response to molecule of bacterial origin	GO:0002237	194	0.015
ribose phosphate metabolic process	GO:0019693	235	0.015
positive regulation of cell differentiation	GO:0045597	217	0.015
dendrite morphogenesis	GO:0048813	43	0.015
positive regulation of protein phosphorylation	GO:0001934	135	0.015
regulation of stem cell differentiation	GO:2000736	2	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.015
cellular response to reactive oxygen species	GO:0034614	55	0.015
response to vitamin	GO:0033273	131	0.015
growth	GO:0040007	165	0.015
positive regulation of neurogenesis	GO:0050769	165	0.015
organonitrogen compound biosynthetic process	GO:1901566	167	0.015
epithelium development	GO:0060429	96	0.015
macromolecular complex subunit organization	GO:0043933	339	0.015
negative regulation of innate immune response	GO:0045824	4	0.014
cellular response to oxidative stress	GO:0034599	76	0.014
glucose homeostasis	GO:0042593	75	0.014
regulation of cellular response to stress	GO:0080135	49	0.014
positive regulation of cell death	GO:0010942	184	0.014
multicellular organismal reproductive process	GO:0048609	233	0.014
heart morphogenesis	GO:0003007	3	0.014
positive regulation of cell communication	GO:0010647	271	0.014
intracellular protein transport	GO:0006886	79	0.014
immune response	GO:0006955	104	0.014
ribonucleotide biosynthetic process	GO:0009260	85	0.014
peptide transport	GO:0015833	97	0.014
nitrogen compound transport	GO:0071705	229	0.014
response to extracellular stimulus	GO:0009991	380	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.014
male sex differentiation	GO:0046661	64	0.014
morphogenesis of embryonic epithelium	GO:0016331	3	0.014
positive regulation of nervous system development	GO:0051962	178	0.014
blood circulation	GO:0008015	183	0.014
anterior posterior pattern specification	GO:0009952	1	0.014
oxidation reduction process	GO:0055114	304	0.014
cellular response to hormone stimulus	GO:0032870	247	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
response to radiation	GO:0009314	137	0.013
organophosphate biosynthetic process	GO:0090407	143	0.013
establishment of tissue polarity	GO:0007164	2	0.013
positive regulation of rna biosynthetic process	GO:1902680	197	0.013
purine nucleotide biosynthetic process	GO:0006164	83	0.013
ras protein signal transduction	GO:0007265	29	0.013
hematopoietic progenitor cell differentiation	GO:0002244	2	0.013
purine ribonucleotide biosynthetic process	GO:0009152	81	0.013
cytoplasmic transport	GO:0016482	115	0.013
cell motility	GO:0048870	202	0.013
regulation of calcium ion transport	GO:0051924	77	0.013
response to decreased oxygen levels	GO:0036293	237	0.013
cellular response to organonitrogen compound	GO:0071417	197	0.013
comma shaped body morphogenesis	GO:0072049	2	0.013
nucleotide biosynthetic process	GO:0009165	98	0.013
lipid metabolic process	GO:0006629	283	0.013
multicellular organism growth	GO:0035264	1	0.013
peptide hormone secretion	GO:0030072	84	0.013
positive regulation of protein transport	GO:0051222	41	0.013
cellular response to peptide	GO:1901653	133	0.013
mapk cascade	GO:0000165	140	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
positive regulation of protein kinase activity	GO:0045860	73	0.012
carbohydrate derivative metabolic process	GO:1901135	346	0.012
negative regulation of molecular function	GO:0044092	133	0.012
regulation of cell cycle	GO:0051726	73	0.012
peptide metabolic process	GO:0006518	32	0.012
protein autophosphorylation	GO:0046777	66	0.012
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.012
ribose phosphate biosynthetic process	GO:0046390	87	0.012
cellular lipid metabolic process	GO:0044255	208	0.012
regulation of locomotion	GO:0040012	148	0.012
response to metal ion	GO:0010038	253	0.012
cellular response to insulin stimulus	GO:0032869	81	0.012
negative regulation of biosynthetic process	GO:0009890	168	0.012
carboxylic acid transport	GO:0046942	115	0.012
cellular response to organic cyclic compound	GO:0071407	202	0.012
immune system process	GO:0002376	204	0.012
regulation of organelle organization	GO:0033043	80	0.012
regulation of membrane potential	GO:0042391	110	0.012
neuromuscular synaptic transmission	GO:0007274	2	0.012
organic cyclic compound catabolic process	GO:1901361	175	0.012
cellular catabolic process	GO:0044248	295	0.012
response to glucocorticoid	GO:0051384	223	0.012
regulation of metal ion transport	GO:0010959	118	0.012
ribonucleotide metabolic process	GO:0009259	231	0.012
regeneration	GO:0031099	163	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
nucleoside phosphate metabolic process	GO:0006753	283	0.011
carbohydrate homeostasis	GO:0033500	75	0.011
sensory perception	GO:0007600	101	0.011	Human
regulation of system process	GO:0044057	208	0.011
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.011
response to reactive oxygen species	GO:0000302	120	0.011
metestrus	GO:0060210	1	0.011
positive regulation of neuron projection development	GO:0010976	99	0.011
muscle structure development	GO:0061061	87	0.011
sodium ion transmembrane transport	GO:0035725	67	0.011
regulation of transmembrane transport	GO:0034762	122	0.011
signal release	GO:0023061	145	0.011
purine containing compound catabolic process	GO:0072523	138	0.011
regulation of cell adhesion	GO:0030155	52	0.011
regulation of kinase activity	GO:0043549	117	0.011
development of primary sexual characteristics	GO:0045137	107	0.011
regulation of catabolic process	GO:0009894	113	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.011
sequestering of calcium ion	GO:0051208	8	0.011
heterocycle catabolic process	GO:0046700	167	0.011
regulation of homeostatic process	GO:0032844	101	0.011
organic acid transport	GO:0015849	116	0.011
organ regeneration	GO:0031100	101	0.011
smooth muscle cell proliferation	GO:0048659	77	0.010
purine ribonucleoside metabolic process	GO:0046128	168	0.010
non canonical wnt signaling pathway	GO:0035567	3	0.010
negative regulation of catalytic activity	GO:0043086	103	0.010
response to nicotine	GO:0035094	51	0.010
negative regulation of rna biosynthetic process	GO:1902679	118	0.010
response to growth factor	GO:0070848	189	0.010
purine nucleotide metabolic process	GO:0006163	229	0.010
regulation of cellular component biogenesis	GO:0044087	86	0.010
behavior	GO:0007610	205	0.010
negative regulation of cellular protein metabolic process	GO:0032269	106	0.010
cellular response to hypoxia	GO:0071456	51	0.010
single organism behavior	GO:0044708	130	0.010
lipid biosynthetic process	GO:0008610	128	0.010
wound healing	GO:0042060	122	0.010

Atp6v1b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.031
disease of anatomical entity	DOID:7	0.031
sensory system disease	DOID:0050155	0.019
eye disease	DOID:5614	0.016
eye and adnexa disease	DOID:1492	0.016
retinal disease	DOID:5679	0.012
gastrointestinal system disease	DOID:77	0.010

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